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Search of human proteins with 22091454
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens] 439 e-124
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 416 e-116
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 395 e-110
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens] 393 e-110
gi|113417526 PREDICTED: similar to glutathione S-transferase alp... 266 1e-71
gi|169169045 PREDICTED: similar to glutathione S-transferase alp... 265 3e-71
gi|113418092 PREDICTED: similar to glutathione S-transferase alp... 265 3e-71
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens] 254 5e-68
gi|4504183 glutathione transferase [Homo sapiens] 86 3e-17
gi|7657457 prostaglandin-D synthase [Homo sapiens] 69 4e-12
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens] 63 2e-10
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens] 63 2e-10
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi... 60 2e-09
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens] 56 3e-08
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens] 55 6e-08
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens] 51 9e-07
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens] 50 2e-06
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens] 49 4e-06
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens] 45 4e-05
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens] 43 2e-04
gi|24797148 selenophosphate synthetase 1 [Homo sapiens] 30 2.1
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] 29 2.8
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 29 2.8
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 29 2.8
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 29 2.8
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 29 2.8
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 29 2.8
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept... 29 3.7
gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi... 29 3.7
gi|44955921 ELK3 protein [Homo sapiens] 29 3.7
>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
Length = 222
Score = 439 bits (1129), Expect = e-124
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
Query: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
Length = 222
Score = 416 bits (1068), Expect = e-116
Identities = 211/222 (95%), Positives = 215/222 (96%)
Query: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMILLLP PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
Query: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 395 bits (1015), Expect = e-110
Identities = 201/222 (90%), Positives = 208/222 (93%)
Query: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI
Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMILLLP+C PEEKDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
Query: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
+ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
Length = 222
Score = 393 bits (1009), Expect = e-110
Identities = 200/222 (90%), Positives = 207/222 (93%)
Query: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHY NARG MES RWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMY EGI DL EMILLL +C PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
Query: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
AL+KEKIKNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEEARKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 266 bits (680), Expect = 1e-71
Identities = 146/210 (69%), Positives = 163/210 (77%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYIASKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65
Query: 88 ERA---------LIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEK 138
ERA +DMYIEG A L E +L + PPEEKDAKLALIKE + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPMDEKSLEEARKIFR 221
PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 227
Score = 265 bits (676), Expect = 3e-71
Identities = 145/209 (69%), Positives = 162/209 (77%), Gaps = 16/209 (7%)
Query: 29 EFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKE 88
E E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYI SKYNL GKDIKE
Sbjct: 18 ESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKE 77
Query: 89 RA---------LIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKV 139
RA +DMYIEG A L E +L + PPEEKDAKLALIKE + YFP FE V
Sbjct: 78 RAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETV 137
Query: 140 LKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNLP 192
LKSH QDYL+GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS LP
Sbjct: 138 LKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLP 197
Query: 193 TVKKFLQPGSPRKPPMDEKSLEEARKIFR 221
TVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 198 TVKKFLQPGSLRKLPIDAKGLQEATKIFK 226
>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 265 bits (676), Expect = 3e-71
Identities = 145/210 (69%), Positives = 162/210 (77%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYI SKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65
Query: 88 ERA---------LIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEK 138
ERA +DMYIEG A L E +L + PPEEKDAKLALIKE + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPMDEKSLEEARKIFR 221
PTVKKFLQPGS RK P+D K L+EA KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
Length = 222
Score = 254 bits (648), Expect = 5e-68
Identities = 119/221 (53%), Positives = 170/221 (76%)
Query: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MA +PKLHY N RGRMES RW+LAAAGVEF+E+F+++ E L KL++ +L+FQQVPMVEI
Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY+EG DL E++++ P P+++ +
Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
Query: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
+ + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S+FP
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFR 221
L+ ++SN+PT+K+FL+PGS +KPP DE + IFR
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
>gi|4504183 glutathione transferase [Homo sapiens]
Length = 210
Score = 85.5 bits (210), Expect = 3e-17
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Query: 9 YFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQT 68
YF RGR + R LLA G ++E+ + + E + ++ Q+P + + L Q+
Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66
Query: 69 RAILNYIASKYNLYGKDIKERALIDMYIEGIADLG-EMILLLPVCPPEEKDAKLALIKEK 127
IL ++ LYGKD +E AL+DM +G+ DL + I L+ KD + + +
Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126
Query: 128 IKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALK 185
+K FE +L + G+ ++VG+++S AD +L++LL E L + +FPLL A
Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181
Query: 186 TRISNLPTVKKFL 198
R+S P +K FL
Sbjct: 182 GRLSARPKLKAFL 194
>gi|7657457 prostaglandin-D synthase [Homo sapiens]
Length = 199
Score = 68.6 bits (166), Expect = 4e-12
Identities = 51/200 (25%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 6 KLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65
KL YFN RGR E R++ A +++E+ I+ A D ++++ L F ++P++E+DG+ L
Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDGLTL 61
Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIK 125
Q+ AI Y+ +L G E+ +D ++ + D + P EK +K
Sbjct: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDD------FMSCFPWAEKKQD---VK 112
Query: 126 EKIKNRYF----PAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179
E++ N P + L ++ G+++L+GN ++ AD + + L+ + P
Sbjct: 113 EQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHP 172
Query: 180 LLKALKTRISNLPTVKKFLQ 199
L L+ ++ +P V +++
Sbjct: 173 RLVTLRKKVQAIPAVANWIK 192
>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
Length = 218
Score = 63.2 bits (152), Expect = 2e-10
Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 24/206 (11%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y+N RG S R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L P
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPD---- 119
Query: 119 AKLALIKEKIKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELDSS 173
EK+K Y A ++LK + Q + +G+K++ D ++L + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
Length = 225
Score = 62.8 bits (151), Expect = 2e-10
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 22/224 (9%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59
L Y++ RG + R LL +EEK E D R+ L F +P +
Sbjct: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D ++ L C +
Sbjct: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRL--CYSSD--- 123
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK+K +Y LK + G KL+ D ++L D
Sbjct: 124 -----HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARK 218
+ FP LKA R L + +LQ K P++ K + K
Sbjct: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222
>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
sapiens]
Length = 191
Score = 59.7 bits (143), Expect = 2e-09
Identities = 58/197 (29%), Positives = 91/197 (46%), Gaps = 24/197 (12%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y+N RG S R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L P
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPD---- 119
Query: 119 AKLALIKEKIKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELDSS 173
EK+K Y A ++LK + Q + +G+K++ D ++L + + S
Sbjct: 120 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 173
Query: 174 LISSFPLLKALKTRISN 190
+ +FP LK +R +
Sbjct: 174 CLDAFPNLKDFISRFEH 190
>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
Length = 218
Score = 55.8 bits (133), Expect = 3e-08
Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 22/205 (10%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D M L + PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK+K +Y + LK + + + GNK++ D + ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
Length = 218
Score = 54.7 bits (130), Expect = 6e-08
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D+ + + P
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD----- 119
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK+K Y +++ Q + VG+K++ D ++L + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
Length = 195
Score = 50.8 bits (120), Expect = 9e-07
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 22/193 (11%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D+ + + P
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD----- 119
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK+K Y +++ Q + VG+K++ D ++L + +
Sbjct: 120 -----FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNC 174
Query: 175 ISSFPLLKALKTR 187
+ +FP LK +R
Sbjct: 175 LDAFPNLKDFISR 187
>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
Length = 218
Score = 49.7 bits (117), Expect = 2e-06
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y++ RG + R LL + EK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ + D M L+ P+
Sbjct: 65 DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK+K +Y + LK + + + G+K++ D ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +F LK +R L + +++
Sbjct: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
Length = 216
Score = 48.5 bits (114), Expect = 4e-06
Identities = 49/193 (25%), Positives = 91/193 (47%), Gaps = 8/193 (4%)
Query: 2 AEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMV 58
A KP L+ + R LA G+++E I +D + + + +QVP +
Sbjct: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTL 62
Query: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPE 115
+IDG+ + Q+ AI+ Y+ L +D K+RA + M + IA + + L V
Sbjct: 63 KIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQV 122
Query: 116 EKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175
++ +L + I F A E++L+S Y VG++++ AD+ LV + E L
Sbjct: 123 GEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL- 180
Query: 176 SSFPLLKALKTRI 188
+ +P + ++ R+
Sbjct: 181 TPYPTISSINKRL 193
>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
Length = 161
Score = 45.4 bits (106), Expect = 4e-05
Identities = 38/139 (27%), Positives = 71/139 (51%), Gaps = 5/139 (3%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYIEGIADLGEMILLL 109
+QVP ++IDG+ + Q+ AI+ Y+ L +D K+RA + M + IA + + L
Sbjct: 2 KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61
Query: 110 PVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEE 169
V ++ +L + I F A E++L+S Y VG++++ AD+ LV + E
Sbjct: 62 SVLKQVGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120
Query: 170 LDSSLISSFPLLKALKTRI 188
L + +P + ++ R+
Sbjct: 121 FKVDL-TPYPTISSINKRL 138
>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
Length = 181
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/158 (28%), Positives = 71/158 (44%), Gaps = 22/158 (13%)
Query: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119
K+ Q+ AIL YIA K+NL G+ +E+ +D+ D M L + PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNK 152
EK+K +Y + LK + + + GNK
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK 152
>gi|24797148 selenophosphate synthetase 1 [Homo sapiens]
Length = 392
Score = 29.6 bits (65), Expect = 2.1
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPV---CPPEEKD 118
G+ LVQT + I + G+ L D+Y G+ + M++LL V E+D
Sbjct: 79 GLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERD 138
Query: 119 AKLALIKEKIKN 130
+ LI + K+
Sbjct: 139 KVMPLIIQGFKD 150
>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
Length = 240
Score = 29.3 bits (64), Expect = 2.8
Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKERALIDMYI 96
++VP ++ L ++ AIL Y+ KY + Y +D++ RA +D Y+
Sbjct: 52 KKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYL 99
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 29.3 bits (64), Expect = 2.8
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 13 RGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 657 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 716
Query: 73 NYIASKYNLYGKDIKER 89
+Y S Y Y K+ +R
Sbjct: 717 SYDGSSYTTYMKEEVDR 733
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 29.3 bits (64), Expect = 2.8
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 13 RGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 579 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 638
Query: 73 NYIASKYNLYGKDIKER 89
+Y S Y Y K+ +R
Sbjct: 639 SYDGSSYTTYMKEEVDR 655
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 29.3 bits (64), Expect = 2.8
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 13 RGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 599 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 658
Query: 73 NYIASKYNLYGKDIKER 89
+Y S Y Y K+ +R
Sbjct: 659 SYDGSSYTTYMKEEVDR 675
>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 29.3 bits (64), Expect = 2.8
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 13 RGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 657 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 716
Query: 73 NYIASKYNLYGKDIKER 89
+Y S Y Y K+ +R
Sbjct: 717 SYDGSSYTTYMKEEVDR 733
>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
sapiens]
Length = 2383
Score = 29.3 bits (64), Expect = 2.8
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 13 RGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 694 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 753
Query: 73 NYIASKYNLYGKDIKER 89
+Y S Y Y K+ +R
Sbjct: 754 SYDGSSYTTYMKEEVDR 770
>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
[Homo sapiens]
Length = 1068
Score = 28.9 bits (63), Expect = 3.7
Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 145 QDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKAL 184
+ YL +KLS+ I LV++L Y + LD+ L+ F L KAL
Sbjct: 620 EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLV-RFLLKKAL 658
>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
sapiens]
Length = 174
Score = 28.9 bits (63), Expect = 3.7
Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRI 188
F A E++L+S Y VG++++ AD+ LV + E L + +P + ++ R+
Sbjct: 97 FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPYPTISSINKRL 151
>gi|44955921 ELK3 protein [Homo sapiens]
Length = 407
Score = 28.9 bits (63), Expect = 3.7
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
E + S L SSF + + N P K ++ +PP D +EE R + RF
Sbjct: 136 EYIHSGLYSSFTI-----NSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVRTVIRF 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,875,227
Number of Sequences: 37866
Number of extensions: 302780
Number of successful extensions: 868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 826
Number of HSP's gapped (non-prelim): 36
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.