Guide to the Human Genome
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Name: MAP3K8 Sequence: fasta or formatted (467aa) NCBI GI: 22035598
Description:

mitogen-activated protein kinase kinase kinase 8

Referenced in:

MAP Kinase Pathways
Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         26           2
 C cysteine            1.7          8           1
 D aspartate           5.8         27           2
 E glutamate           8.1         38           2
 F phenylalanine       2.8         13           1
 G glycine             5.8         27           2
 H histidine           3.0         14           2
 I isoleucine          6.4         30           2
 K lysine              5.6         26           2
 L leucine            11.1         52           3
 M methionine          3.2         15           1
 N asparagine          3.6         17           1
 P proline             6.0         28           2
 Q glutamine           3.4         16           1
 R arginine            5.4         25           1
 S serine              7.9         37           2
 T threonine           4.1         19           1
 V valine              5.4         25           1
 W tryptophan          1.1          5           1
 Y tyrosine            4.1         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase 8 [Ho... 
MST4                  0.129   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.127   serine/threonine kinase 24 isoform b 
STK24                 0.127   serine/threonine kinase 24 isoform a 
STK25                 0.119   serine/threonine kinase 25 
MAP3K14               0.115   mitogen-activated protein kinase kinase kinase 14 [...
MST4                  0.108   serine/threonine protein kinase MST4 isoform 2 [Hom...
MAP3K5                0.105   mitogen-activated protein kinase kinase kinase 5 [Hom...
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 7 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 6 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 5 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 4 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 3 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 2 
TNIK                  0.105   TRAF2 and NCK interacting kinase isoform 1 
MAP3K1                0.102   mitogen-activated protein kinase kinase kinase 1 [H...
MAP4K4                0.101   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.101   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.101   mitogen-activated protein kinase kinase kinase kinas...
MAP4K3                0.100   mitogen-activated protein kinase kinase kinase kinas...
PAK6                  0.100   p21-activated kinase 6 
PAK6                  0.100   p21-activated kinase 6 
PAK6                  0.100   p21-activated kinase 6 
PAK3                  0.100   p21-activated kinase 3 isoform d 
PAK3                  0.100   p21-activated kinase 3 isoform c 
PAK3                  0.100   p21-activated kinase 3 isoform b 
PAK3                  0.100   p21-activated kinase 3 isoform a 
PAK3                  0.100   p21-activated kinase 3 isoform a 
PAK3                  0.100   p21-activated kinase 3 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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