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Search of human proteins with 22027486
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22027486 RASD family, member 2 [Homo sapiens]
(266 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027486 RASD family, member 2 [Homo sapiens] 536 e-153
gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] 343 1e-94
gi|21703367 Di-Ras2 [Homo sapiens] 137 1e-32
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 136 2e-32
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 119 2e-27
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 118 6e-27
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 117 1e-26
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 115 3e-26
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 114 7e-26
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 114 7e-26
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 112 3e-25
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 112 3e-25
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 111 7e-25
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 109 2e-24
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 108 4e-24
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 108 4e-24
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 108 6e-24
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 107 8e-24
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 105 4e-23
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 105 4e-23
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 103 1e-22
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 100 1e-21
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 96 2e-20
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 96 4e-20
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 96 4e-20
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 94 9e-20
gi|4759012 RAB9A, member RAS oncogene family [Homo sapiens] 85 6e-17
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 85 7e-17
gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 84 1e-16
gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 84 1e-16
>gi|22027486 RASD family, member 2 [Homo sapiens]
Length = 266
Score = 536 bits (1382), Expect = e-153
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 60
MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY
Sbjct: 1 MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 60
Query: 61 NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK 120
NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK
Sbjct: 61 NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK 120
Query: 121 SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD 180
SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD
Sbjct: 121 SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD 180
Query: 181 EMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSV 240
EMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSV
Sbjct: 181 EMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSV 240
Query: 241 NSDLKYIKAKVLREGQARERDKCTIQ 266
NSDLKYIKAKVLREGQARERDKCTIQ
Sbjct: 241 NSDLKYIKAKVLREGQARERDKCTIQ 266
>gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens]
Length = 281
Score = 343 bits (879), Expect = 1e-94
Identities = 171/276 (61%), Positives = 216/276 (78%), Gaps = 12/276 (4%)
Query: 1 MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 60
M+K + + LS+PAKN YRMV+LG+S+VGK++IVSRFL GRFED YTPTIEDFHRK Y
Sbjct: 6 MIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFY 65
Query: 61 NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK 120
+IRG++YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+ K
Sbjct: 66 SIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTK 125
Query: 121 SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTNV 179
SCLKNKTKE ++P+VICGNK D + R+V E E LV D + CAYFE+SAKKN+++
Sbjct: 126 SCLKNKTKENVDVPLVICGNKGDR-DFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSL 184
Query: 180 DEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEM----------DAYG 229
D+MF LF+MAKLP EMSP LHRK+SVQY D H + +++ DA+G
Sbjct: 185 DQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFG 244
Query: 230 MVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTI 265
+V+PFARRPSV+SDL YI+ K QA+++++C I
Sbjct: 245 IVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVI 280
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 137 bits (344), Expect = 1e-32
Identities = 75/174 (43%), Positives = 109/174 (62%), Gaps = 9/174 (5%)
Query: 18 NSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGN 77
N YR+ V GA VGKSS+V RF+ G F + Y PT+ED +R+V + + L I DT+G+
Sbjct: 6 NDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGS 65
Query: 78 HPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVI 137
H FPAM+RLSI G FILV+S+ +R+S +E+K + +QI E+K + +P+++
Sbjct: 66 HQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKG-------DVESIPIML 118
Query: 138 CGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAK 191
GNK D R+V ++EAE L + CA+ E SAK N NV E+F L ++ K
Sbjct: 119 VGNKCDESP-SREVQSSEAEAL-ARTWKCAFMETSAKLNHNVKELFQELLNLEK 170
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 136 bits (343), Expect = 2e-32
Identities = 76/172 (44%), Positives = 111/172 (64%), Gaps = 10/172 (5%)
Query: 18 NSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGN 77
N YR+VV GA VGKSS+V RF+ G F D Y PTIED +R+V + + L I DT+G+
Sbjct: 6 NDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGS 65
Query: 78 HPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVI 137
H FPAM+RLSI G FILVFS+ +++S +E+ + K I+++K ++ ++P+++
Sbjct: 66 HQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVE-------DIPVML 118
Query: 138 CGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSM 189
GNK D E R+V T EA+ V+ + CA+ E SAK N NV E+F L ++
Sbjct: 119 VGNKCD--ETQREVDTREAQ-AVAQEWKCAFMETSAKMNYNVKELFQELLTL 167
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 119 bits (299), Expect = 2e-27
Identities = 70/169 (41%), Positives = 100/169 (59%), Gaps = 10/169 (5%)
Query: 15 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDT 74
P ++++VV+G VGKS++ +F+ F Y PTIED + K+ ++ G +LDILDT
Sbjct: 25 PPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDT 84
Query: 75 SGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELP 134
+G F AMR + G F+LVF++++R+SF+EV +L QIL V K+ + P
Sbjct: 85 AGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRV--------KDRDDFP 136
Query: 135 MVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
+V+ GNK D E RQVP +EA + AYFE SAK NVDE F
Sbjct: 137 VVLVGNKADL-ESQRQVPRSEASAF-GASHHVAYFEASAKLRLNVDEAF 183
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 118 bits (295), Expect = 6e-27
Identities = 68/164 (41%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEK--------VPVILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
NK D E R+V ++E L + C + E SAK T VDE+F
Sbjct: 116 NKVDL-ESEREVSSSEGRALAE-EWGCPFMETSAKSKTMVDELF 157
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 117 bits (293), Expect = 1e-26
Identities = 68/165 (41%), Positives = 100/165 (60%), Gaps = 12/165 (7%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F +MR L I G FILV+SL N++SF ++K ++ QI+ V K +PM++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRV--------KRYERVPMILVG 115
Query: 140 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
NK D GE R+V E + L + +C + E SAK +VDE+F
Sbjct: 116 NKVDLEGE--REVSYGEGKALAE-EWSCPFMETSAKNKASVDELF 157
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 115 bits (289), Expect = 3e-26
Identities = 67/164 (40%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEK--------VPLILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
NK D E R+V ++E L + C + E SAK + VDE+F
Sbjct: 116 NKVDL-EPEREVMSSEGRALAQ-EWGCPFMETSAKSKSMVDELF 157
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 7e-26
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTDDVPMILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 7e-26
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTDDVPMILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 112 bits (280), Expect = 3e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 112 bits (280), Expect = 3e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 111 bits (277), Expect = 7e-25
Identities = 69/170 (40%), Positives = 95/170 (55%), Gaps = 10/170 (5%)
Query: 17 KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSG 76
+ YR+VV+G VGKS++ +F+ F Y PTIED + K I +LDILDT+G
Sbjct: 12 QEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAG 71
Query: 77 NHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMV 136
F AMR + TG+ F+LVFS+ +R SF+E+ + Q+QIL V K+ E PM+
Sbjct: 72 QEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRV--------KDRDEFPMI 123
Query: 137 ICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
+ GNK D RQV E + L + Y E SAK NVD+ F+ L
Sbjct: 124 LIGNKADLDHQ-RQVTQEEGQQL-ARQLKVTYMEASAKIRMNVDQAFHEL 171
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 109 bits (273), Expect = 2e-24
Identities = 63/167 (37%), Positives = 98/167 (58%), Gaps = 11/167 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF+++ ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI--------KRVKDSEDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D R V T +A+ L + + E SAK VD+ FY L
Sbjct: 116 NKCDLPS--RTVDTKQAQDL-ARSYGIPFIETSAKTRQGVDDAFYTL 159
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 108 bits (271), Expect = 4e-24
Identities = 62/167 (37%), Positives = 99/167 (59%), Gaps = 11/167 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF+++ + ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--------KRVKDSDDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D R V + +A+ L + Y E SAK V++ FY L
Sbjct: 116 NKCDLA--ARTVESRQAQDL-ARSYGIPYIETSAKTRQGVEDAFYTL 159
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 108 bits (271), Expect = 4e-24
Identities = 62/167 (37%), Positives = 99/167 (59%), Gaps = 11/167 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF+++ + ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--------KRVKDSDDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D R V + +A+ L + Y E SAK V++ FY L
Sbjct: 116 NKCDLA--ARTVESRQAQDL-ARSYGIPYIETSAKTRQGVEDAFYTL 159
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 108 bits (269), Expect = 6e-24
Identities = 62/167 (37%), Positives = 98/167 (58%), Gaps = 11/167 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF+++ ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI--------KRVKDSEDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D R V T +A+ L + + E SAK V++ FY L
Sbjct: 116 NKCDLPS--RTVDTKQAQDL-ARSYGIPFIETSAKTRQRVEDAFYTL 159
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 107 bits (268), Expect = 8e-24
Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 10/185 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++V+LGA VGKS++ +F++ +F D + PTIED ++ I + LDILDT+G
Sbjct: 21 YKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAE 80
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
F AMR + G+ FI+ +S+ +R+SF E + ++ I +V + E+P+V+ G
Sbjct: 81 FTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQV--------RHTYEIPLVLVG 132
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPA 199
NK D E RQV +TE L ++ + NC +FE SA +D+ F+ L + M
Sbjct: 133 NKIDL-EQFRQV-STEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPSL 190
Query: 200 LHRKI 204
+ +K+
Sbjct: 191 MEKKL 195
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 105 bits (262), Expect = 4e-23
Identities = 62/167 (37%), Positives = 95/167 (56%), Gaps = 11/167 (6%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF ++ ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI--------KRVKDSDDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK D R V T +A L + E SAK V++ FY L
Sbjct: 116 NKCDLP--TRTVDTKQAHELAK-SYGIPFIETSAKTRQGVEDAFYTL 159
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 105 bits (262), Expect = 4e-23
Identities = 62/177 (35%), Positives = 101/177 (57%), Gaps = 10/177 (5%)
Query: 10 CTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQL 69
C+ Y++V+LGA VGKS++ +F++ RF + + PTIED ++ I + L
Sbjct: 12 CSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANL 71
Query: 70 DILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKE 129
DILDT+G F AMR + G+ FI+ +S+ +R SF EV+ ++ I V +
Sbjct: 72 DILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRV--------RR 123
Query: 130 AAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
+ P+V+ GNK+D +L RQV T E L ++ + +C +FE SA +D++F+ L
Sbjct: 124 TDDTPVVLVGNKSDLKQL-RQV-TKEEGLALAREFSCPFFETSAAYRYYIDDVFHAL 178
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 103 bits (258), Expect = 1e-22
Identities = 64/186 (34%), Positives = 103/186 (55%), Gaps = 14/186 (7%)
Query: 1 MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 60
M S G +L++ ++++++G+ VGKS++ +F+ F + Y PT D +RK
Sbjct: 1 MAANKSKGQSSLAL-----HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKV 55
Query: 61 NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK 120
+ G+ Q+DILDT+G + A+R +G+ F+LVFS+ ESF ++QIL VK
Sbjct: 56 VLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVK 115
Query: 121 SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD 180
+ E ++P+++ GNK+D E RQVP EA + Y E SAK NVD
Sbjct: 116 A-------EEDKIPLLVVGNKSDLEER-RQVPVEEARSKAE-EWGVQYVETSAKTRANVD 166
Query: 181 EMFYVL 186
++F+ L
Sbjct: 167 KVFFDL 172
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 100 bits (249), Expect = 1e-21
Identities = 58/155 (37%), Positives = 93/155 (60%), Gaps = 11/155 (7%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ AMR + TG+ F+ VF+++N +SF+++ + ++QI + K++ ++PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--------KRVKDSDDVPMVLVG 115
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAK 174
NK D R V + +A+ L + Y E SAK
Sbjct: 116 NKCDLA--ARTVESRQAQDL-ARSYGIPYIETSAK 147
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 96.3 bits (238), Expect = 2e-20
Identities = 54/174 (31%), Positives = 97/174 (55%), Gaps = 9/174 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
YR+VV+G + VGKS+++ ++ +G F +Y PTIE+ + ++ + L I D+
Sbjct: 38 YRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDG 97
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
A++R I G F+LV+S+ +E+ +E+K + I ++K + P+V+ G
Sbjct: 98 NRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKG------NNLHKFPIVLVG 151
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLP 193
NK+D + R+V + + NCA+ E+SAK + NV E+F++L + K P
Sbjct: 152 NKSD--DTHREVALNDGATCAM-EWNCAFMEISAKTDVNVQELFHMLLNYKKKP 202
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 95.5 bits (236), Expect = 4e-20
Identities = 66/179 (36%), Positives = 96/179 (53%), Gaps = 13/179 (7%)
Query: 11 TLSVPAKN--SYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQ 68
T +VP+ N +Y++VV+G VGKS++ +F F Y PTIED + K I
Sbjct: 3 TSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAI 62
Query: 69 LDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTK 128
LD+LDT+G F AMR + TGD F++V+S+ ++ SF+ V R + IL V K
Sbjct: 63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRV--------K 114
Query: 129 EAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAK-KNTNVDEMFYVL 186
+ PM++ NK D L R++ T E ++ N Y E SAK NVD+ F+ L
Sbjct: 115 DRESFPMILVANKVDLMHL-RKI-TREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDL 171
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 95.5 bits (236), Expect = 4e-20
Identities = 66/179 (36%), Positives = 96/179 (53%), Gaps = 13/179 (7%)
Query: 11 TLSVPAKN--SYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQ 68
T +VP+ N +Y++VV+G VGKS++ +F F Y PTIED + K I
Sbjct: 3 TSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAI 62
Query: 69 LDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTK 128
LD+LDT+G F AMR + TGD F++V+S+ ++ SF+ V R + IL V K
Sbjct: 63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRV--------K 114
Query: 129 EAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAK-KNTNVDEMFYVL 186
+ PM++ NK D L R++ T E ++ N Y E SAK NVD+ F+ L
Sbjct: 115 DRESFPMILVANKVDLMHL-RKI-TREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDL 171
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 94.4 bits (233), Expect = 9e-20
Identities = 59/167 (35%), Positives = 92/167 (55%), Gaps = 10/167 (5%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
++++++G+ VGKS++ +F+ F + Y PT D +RK + G+ Q+DILDT+G
Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74
Query: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
+ A+R +G+ F+ VFS+ ESF ++QIL V KE +P ++ G
Sbjct: 75 YAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRV--------KEDENVPFLLVG 126
Query: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 186
NK+D E RQV EA+ N Y E SAK NVD++F+ L
Sbjct: 127 NKSDL-EDKRQVSVEEAKNRAE-QWNVNYVETSAKTRANVDKVFFDL 171
>gi|4759012 RAB9A, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 85.1 bits (209), Expect = 6e-17
Identities = 55/165 (33%), Positives = 84/165 (50%), Gaps = 8/165 (4%)
Query: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIE-DFHRKVYNIRGDMYQLDILDTSGNH 78
+++++LG VGKSS+++R++ +F+ Q TI +F K + G + I DT+G
Sbjct: 8 FKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67
Query: 79 PFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVIC 138
F ++R D +L FS+D+ +SF + +K+ + KE P VI
Sbjct: 68 RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYAD-----VKEPESFPFVIL 122
Query: 139 GNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
GNK D E RQV T EA+ + + YFE SAK TNV F
Sbjct: 123 GNKIDISE--RQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAF 165
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 84.7 bits (208), Expect = 7e-17
Identities = 50/171 (29%), Positives = 93/171 (54%), Gaps = 12/171 (7%)
Query: 14 VPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILD 73
+P S ++ +LG VGKSS+ +F+ G+F D Y PTIE+ K+ + G Y L ++D
Sbjct: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
Query: 74 TSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAEL 133
T+G + + + + +ILV+S+ + +SF+ +K + ++L++ ++
Sbjct: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVG--------KVQI 112
Query: 134 PMVICGNKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
P+++ GNK D H E +V + E ++ N A+ E SAK+N ++F
Sbjct: 113 PIMLVGNKKDLHME---RVISYEEGKALAESWNAAFLESSAKENQTAVDVF 160
>gi|169160721 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/143 (39%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Query: 44 FEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR 103
F Y PT ED + K I +LDILDT+G AMR + TG+ F+LVFS+ +R
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 104 ESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD 163
SF+E+ + Q+QIL V K+ E PM++ GNK D RQV E L +
Sbjct: 80 GSFEEIYKFQRQILRV--------KDRDEFPMILIGNKADLDHQ-RQVTQEEGRQL-ARQ 129
Query: 164 ENCAYFEVSAKKNTNVDEMFYVL 186
Y E SAK NVD+ F+ L
Sbjct: 130 LKVTYMEASAKIRMNVDQAFHEL 152
>gi|169161589 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/143 (39%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Query: 44 FEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR 103
F Y PT ED + K I +LDILDT+G AMR + TG+ F+LVFS+ +R
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 104 ESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD 163
SF+E+ + Q+QIL V K+ E PM++ GNK D RQV E L +
Sbjct: 80 GSFEEIYKFQRQILRV--------KDRDEFPMILIGNKADLDHQ-RQVTQEEGRQL-ARQ 129
Query: 164 ENCAYFEVSAKKNTNVDEMFYVL 186
Y E SAK NVD+ F+ L
Sbjct: 130 LKVTYMEASAKIRMNVDQAFHEL 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,734,479
Number of Sequences: 37866
Number of extensions: 409521
Number of successful extensions: 1481
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 1144
Number of HSP's gapped (non-prelim): 199
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.