BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens] (934 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens] 1879 0.0 gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens] 1850 0.0 gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens] 1848 0.0 gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens] 362 1e-99 gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens] 349 8e-96 gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens] 329 6e-90 gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens] 329 6e-90 gi|116536089 phosphodiesterase 11A isoform 2 [Homo sapiens] 320 5e-87 gi|116536083 phosphodiesterase 11A isoform 1 [Homo sapiens] 303 5e-82 gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens] 288 2e-77 gi|61744432 phosphodiesterase 5A isoform 3 [Homo sapiens] 288 2e-77 gi|61744430 phosphodiesterase 5A isoform 2 [Homo sapiens] 288 2e-77 gi|223718037 phosphodiesterase 6B isoform 2 [Homo sapiens] 283 4e-76 gi|105990537 phosphodiesterase 6B isoform 1 [Homo sapiens] 282 1e-75 gi|157364939 phosphodiesterase 6C [Homo sapiens] 259 1e-68 gi|170650674 phosphodiesterase 6A [Homo sapiens] 256 9e-68 gi|223718019 phosphodiesterase 6B isoform 3 [Homo sapiens] 249 8e-66 gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens] 156 7e-38 gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens] 156 7e-38 gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens] 156 7e-38 gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens] 156 7e-38 gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens] 156 7e-38 gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens] 156 7e-38 gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens] 156 7e-38 gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens] 156 7e-38 gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens] 156 7e-38 gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens] 156 7e-38 gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens] 156 7e-38 gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens] 156 7e-38 gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens] 156 7e-38 >gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens] Length = 934 Score = 1879 bits (4867), Expect = 0.0 Identities = 934/934 (100%), Positives = 934/934 (100%) Query: 1 MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAV 60 MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAV Sbjct: 1 MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAV 60 Query: 61 KEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDL 120 KEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDL Sbjct: 61 KEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDL 120 Query: 121 PGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVA 180 PGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVA Sbjct: 121 PGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVA 180 Query: 181 LRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQL 240 LRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQL Sbjct: 181 LRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQL 240 Query: 241 KVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQ 300 KVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQ Sbjct: 241 KVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQ 300 Query: 301 LKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQ 360 LKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQ Sbjct: 301 LKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQ 360 Query: 361 HCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNA 420 HCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNA Sbjct: 361 HCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNA 420 Query: 421 EICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLF 480 EICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLF Sbjct: 421 EICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLF 480 Query: 481 YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGIS 540 YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGIS Sbjct: 481 YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGIS 540 Query: 541 IAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTP 600 IAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTP Sbjct: 541 IAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTP 600 Query: 601 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHF 660 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHF Sbjct: 601 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHF 660 Query: 661 CYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVME 720 CYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVME Sbjct: 661 CYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVME 720 Query: 721 RHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG 780 RHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG Sbjct: 721 RHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG 780 Query: 781 YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEM 840 YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEM Sbjct: 781 YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEM 840 Query: 841 MDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL 900 MDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL Sbjct: 841 MDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL 900 Query: 901 PSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE 934 PSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE Sbjct: 901 PSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE 934 >gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens] Length = 932 Score = 1850 bits (4791), Expect = 0.0 Identities = 918/918 (100%), Positives = 918/918 (100%) Query: 17 RRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYT 76 RRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYT Sbjct: 15 RRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYT 74 Query: 77 YLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDT 136 YLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDT Sbjct: 75 YLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDT 134 Query: 137 QVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAP 196 QVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAP Sbjct: 135 QVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAP 194 Query: 197 RAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCC 256 RAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCC Sbjct: 195 RAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCC 254 Query: 257 LLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSML 316 LLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSML Sbjct: 255 LLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSML 314 Query: 317 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 376 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF Sbjct: 315 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 374 Query: 377 QKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAK 436 QKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAK Sbjct: 375 QKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAK 434 Query: 437 VFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNIL 496 VFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNIL Sbjct: 435 VFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNIL 494 Query: 497 CFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYR 556 CFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYR Sbjct: 495 CFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYR 554 Query: 557 SHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSML 616 SHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSML Sbjct: 555 SHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSML 614 Query: 617 QDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLED 676 QDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLED Sbjct: 615 QDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLED 674 Query: 677 IEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGC 736 IEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGC Sbjct: 675 IEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGC 734 Query: 737 NIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLL 796 NIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLL Sbjct: 735 NIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLL 794 Query: 797 MTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFM 856 MTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFM Sbjct: 795 MTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFM 854 Query: 857 EHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVP 916 EHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVP Sbjct: 855 EHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVP 914 Query: 917 DLDGTRAPINGCCSLDAE 934 DLDGTRAPINGCCSLDAE Sbjct: 915 DLDGTRAPINGCCSLDAE 932 >gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens] Length = 941 Score = 1848 bits (4786), Expect = 0.0 Identities = 917/917 (100%), Positives = 917/917 (100%) Query: 18 RGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTY 77 RGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTY Sbjct: 25 RGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTY 84 Query: 78 LLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQ 137 LLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQ Sbjct: 85 LLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQ 144 Query: 138 VLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPR 197 VLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPR Sbjct: 145 VLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPR 204 Query: 198 AVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCL 257 AVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCL Sbjct: 205 AVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCL 264 Query: 258 LLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLG 317 LLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLG Sbjct: 265 LLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLG 324 Query: 318 CELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQ 377 CELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQ Sbjct: 325 CELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQ 384 Query: 378 KEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKV 437 KEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKV Sbjct: 385 KEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKV 444 Query: 438 FDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILC 497 FDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILC Sbjct: 445 FDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILC 504 Query: 498 FPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRS 557 FPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRS Sbjct: 505 FPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRS 564 Query: 558 HLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQ 617 HLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQ Sbjct: 565 HLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQ 624 Query: 618 DMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDI 677 DMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDI Sbjct: 625 DMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDI 684 Query: 678 EIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCN 737 EIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCN Sbjct: 685 EIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCN 744 Query: 738 IFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLM 797 IFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLM Sbjct: 745 IFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLM 804 Query: 798 TSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFME 857 TSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFME Sbjct: 805 TSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFME 864 Query: 858 HIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPD 917 HIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPD Sbjct: 865 HIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPD 924 Query: 918 LDGTRAPINGCCSLDAE 934 LDGTRAPINGCCSLDAE Sbjct: 925 LDGTRAPINGCCSLDAE 941 >gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens] Length = 933 Score = 362 bits (928), Expect = 1e-99 Identities = 229/722 (31%), Positives = 368/722 (50%), Gaps = 64/722 (8%) Query: 232 DLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGC--- 288 DLD +SL K+L ++ A RC L LV + K + K PL C Sbjct: 215 DLDLTSLSYKILIFVCLMVDADRCSLFLV--EGAAAGKKTLVSKFFDVHAGTPLLPCSST 272 Query: 289 --------------LGQVVEDKKSIQLKDLTSEDV--QQLQSMLGCELQAMLCVPVISRA 332 +G V E +++ + D + ++ + G + +++LC+P+ S + Sbjct: 273 ENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRS-S 331 Query: 333 TDQVVALACAFNKL-EGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQ 391 +++ +A A NK+ EG FT++DE V+Q + +++ F +K +ALL+ Sbjct: 332 DGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLE 391 Query: 392 VAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIR 451 V +LF D+ ++++I+ A+ L E CSV LL+ E F +S+E+ Sbjct: 392 VVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFT------KSFELM 445 Query: 452 IPA-----------------------DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDST 488 P + IA VA+TG +NI DAY P F D + Sbjct: 446 SPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQIS 505 Query: 489 GFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYK 548 GF R++LC PI N N ++IGVA+++N+++G F D+ L AF I+CG+ I ++++Y Sbjct: 506 GFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYD 565 Query: 549 KVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAI---DSNFASFTYTPRSLPE 605 +V ++ + +A +++ YH S E K I V+ + D +F F SL Sbjct: 566 QVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDF-----SLDV 620 Query: 606 DDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLY 665 D A L M ++ + +KID TL R+ L V+K YR YHNW HAF+V + + Sbjct: 621 DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAML 680 Query: 666 KNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFA 725 + L ++EI A+ + C+CHDLDHRGTNN+FQ S S LA LY + + +E HHF Sbjct: 681 TTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFN 739 Query: 726 QAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRN 784 A+ IL + G NIF + S K+Y ++ L++ ILATDL + + ++ G YD N Sbjct: 740 HAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWN 799 Query: 785 NKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR 843 K H + +LMT+CDL TK W+ +R++AEL+ EFF QGD E+ + P + DR Sbjct: 800 IKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDR 859 Query: 844 -EKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPS 902 K +P LQ+ +++ I MP+Y+ L + K + + VA+NR W ++ K + S Sbjct: 860 NRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTAS 919 Query: 903 NN 904 ++ Sbjct: 920 SS 921 >gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens] Length = 683 Score = 349 bits (895), Expect = 8e-96 Identities = 210/639 (32%), Positives = 340/639 (53%), Gaps = 45/639 (7%) Query: 296 KKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKL-EGDLFTDE 354 ++ + KD D ++ + G + +++LC+P+ S + +++ +A A NK+ EG FT++ Sbjct: 48 QRQTKTKDRRFND--EIDKLTGYKTKSLLCMPIRS-SDGEIIGVAQAINKIPEGAPFTED 104 Query: 355 DEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEA 414 DE V+Q + +++ F +K +ALL+V +LF D+ ++++I+ A Sbjct: 105 DEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRA 164 Query: 415 RNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPA-------------------- 454 + L E CSV LL+ E F +S+E+ P Sbjct: 165 QTLLKCERCSVLLLEDIESPVVKFT------KSFELMSPKCSADAENSFKESMEKSSYSD 218 Query: 455 ---DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVA 511 + IA VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA Sbjct: 219 WLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVA 278 Query: 512 ELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVS 571 +++N+++G F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S Sbjct: 279 QVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCS 338 Query: 572 DDEYTKLLHDGIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKID 628 E K I V+ + D +F F SL D A L M ++ + +KID Sbjct: 339 KAEVDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKID 393 Query: 629 CPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMC 688 TL R+ L V+K YR YHNW HAF+V + + + L ++EI A+ + C+C Sbjct: 394 YETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLC 453 Query: 689 HDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 748 HDLDHRGTNN+FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y Sbjct: 454 HDLDHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYS 512 Query: 749 RMLDLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTK 807 ++ L++ ILATDL + + ++ G YD N K H + +LMT+CDL TK Sbjct: 513 DLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTK 572 Query: 808 GWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYK 865 W+ +R++AEL+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ Sbjct: 573 PWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQ 632 Query: 866 LLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 904 L + K + + VA+NR W ++ K + S++ Sbjct: 633 ALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS 671 >gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens] Length = 779 Score = 329 bits (844), Expect = 6e-90 Identities = 208/622 (33%), Positives = 330/622 (53%), Gaps = 43/622 (6%) Query: 292 VVEDKKSIQLKDLTSEDVQQLQSML--GCELQAMLCVPVISRATDQVVALACAFNKLEGD 349 V + +K++ ++D+ ++ + L G +Q++LC+P+++ D ++ + + + Sbjct: 155 VAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGD-LIGILELYRHWGKE 213 Query: 350 LFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQE 409 F + V + S + + K LL V+K F ++ + LL+ Sbjct: 214 AFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEH 273 Query: 410 IITEARNLSNAEICSVFLLDQN--ELVAKVFD------GGVVDDESYEIRIPADQGIAGH 461 I+ A+NL NA+ C++F +D EL + +FD G V ++ EIR ++GIAG Sbjct: 274 IMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ 333 Query: 462 VATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPW 521 VA TG++LNIPDAYA P F R VD TG+ TRNILC PI + VIGV ++VNKI+G Sbjct: 334 VARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-SVIGVVQMVNKISGSA 392 Query: 522 FSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHD 581 FSK DE+ F+++C +++ + +Y ++ ++ + E + YH + +E+ L+ Sbjct: 393 FSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLM-- 450 Query: 582 GIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDM---NFINNYKIDCPT------- 631 FT R E + + ++M F+ C T Sbjct: 451 -------------QFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEK 497 Query: 632 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 691 L RF + VKK YR PYHNW HA +V+H Y + +N D+E L I+C+CHDL Sbjct: 498 LCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNH--TLFTDLERKGLLIACLCHDL 555 Query: 692 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 751 DHRG +NS+ LAALYS+ S ME+HHF+Q ++IL G NIF S +Y+++L Sbjct: 556 DHRGFSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVL 613 Query: 752 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 810 +++R I+ATDLA + K L++M + G + NN+ H ++ L+MT+CDL TK W Sbjct: 614 EIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWP 673 Query: 811 TTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKA-YIPELQISFMEHIAMPIYKLLQD 869 T+ A IY EF+++GD K +G +P+ MMDR+K +P+ Q+ F +A+P Y L Sbjct: 674 VTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQ 733 Query: 870 LFPKAAELYERVASNREHWTKV 891 + P L + N W KV Sbjct: 734 ILPPTEPLLKACRDNLSQWEKV 755 Score = 40.0 bits (92), Expect = 0.010 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Query: 453 PADQG--IAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGV 510 P QG ++ +VA + + L + D F RG +G R +++LC PI ++IG+ Sbjct: 144 PITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGI 203 Query: 511 AELVNKINGPWFSKFDEDLATAFSIYCGISI 541 EL F +++ATA + ++I Sbjct: 204 LELYRHWGKEAFCLSHQEVATANLAWASVAI 234 >gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens] Length = 789 Score = 329 bits (844), Expect = 6e-90 Identities = 208/622 (33%), Positives = 330/622 (53%), Gaps = 43/622 (6%) Query: 292 VVEDKKSIQLKDLTSEDVQQLQSML--GCELQAMLCVPVISRATDQVVALACAFNKLEGD 349 V + +K++ ++D+ ++ + L G +Q++LC+P+++ D ++ + + + Sbjct: 165 VAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGD-LIGILELYRHWGKE 223 Query: 350 LFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQE 409 F + V + S + + K LL V+K F ++ + LL+ Sbjct: 224 AFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEH 283 Query: 410 IITEARNLSNAEICSVFLLDQN--ELVAKVFD------GGVVDDESYEIRIPADQGIAGH 461 I+ A+NL NA+ C++F +D EL + +FD G V ++ EIR ++GIAG Sbjct: 284 IMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ 343 Query: 462 VATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPW 521 VA TG++LNIPDAYA P F R VD TG+ TRNILC PI + VIGV ++VNKI+G Sbjct: 344 VARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-SVIGVVQMVNKISGSA 402 Query: 522 FSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHD 581 FSK DE+ F+++C +++ + +Y ++ ++ + E + YH + +E+ L+ Sbjct: 403 FSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLM-- 460 Query: 582 GIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDM---NFINNYKIDCPT------- 631 FT R E + + ++M F+ C T Sbjct: 461 -------------QFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEK 507 Query: 632 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 691 L RF + VKK YR PYHNW HA +V+H Y + +N D+E L I+C+CHDL Sbjct: 508 LCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNH--TLFTDLERKGLLIACLCHDL 565 Query: 692 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 751 DHRG +NS+ LAALYS+ S ME+HHF+Q ++IL G NIF S +Y+++L Sbjct: 566 DHRGFSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVL 623 Query: 752 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 810 +++R I+ATDLA + K L++M + G + NN+ H ++ L+MT+CDL TK W Sbjct: 624 EIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWP 683 Query: 811 TTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKA-YIPELQISFMEHIAMPIYKLLQD 869 T+ A IY EF+++GD K +G +P+ MMDR+K +P+ Q+ F +A+P Y L Sbjct: 684 VTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQ 743 Query: 870 LFPKAAELYERVASNREHWTKV 891 + P L + N W KV Sbjct: 744 ILPPTEPLLKACRDNLSQWEKV 765 Score = 40.0 bits (92), Expect = 0.010 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Query: 453 PADQG--IAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGV 510 P QG ++ +VA + + L + D F RG +G R +++LC PI ++IG+ Sbjct: 154 PITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGI 213 Query: 511 AELVNKINGPWFSKFDEDLATAFSIYCGISI 541 EL F +++ATA + ++I Sbjct: 214 LELYRHWGKEAFCLSHQEVATANLAWASVAI 244 >gi|116536089 phosphodiesterase 11A isoform 2 [Homo sapiens] Length = 575 Score = 320 bits (819), Expect = 5e-87 Identities = 190/569 (33%), Positives = 299/569 (52%), Gaps = 41/569 (7%) Query: 365 YTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICS 424 + +++ F +K +ALL+V +LF D+ ++++I+ A+ L E CS Sbjct: 7 FCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCS 66 Query: 425 VFLLDQNELVAKVFDGGVVDDESYEIRIPA-----------------------DQGIAGH 461 V LL+ E F +S+E+ P + IA Sbjct: 67 VLLLEDIESPVVKFT------KSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAEL 120 Query: 462 VATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPW 521 VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA+++N+++G Sbjct: 121 VASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKP 180 Query: 522 FSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHD 581 F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S E K Sbjct: 181 FDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAA 240 Query: 582 GIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLM 638 I V+ + D +F F SL D A L M ++ + +KID TL R+ L Sbjct: 241 NIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLT 295 Query: 639 VKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNN 698 V+K YR YHNW HAF+V + + + L ++EI A+ + C+CHDLDHRGTNN Sbjct: 296 VRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNN 355 Query: 699 SFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDII 758 +FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y ++ L++ I Sbjct: 356 AFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSI 414 Query: 759 LATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAE 817 LATDL + + ++ G YD N K H + +LMT+CDL TK W+ +R++AE Sbjct: 415 LATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAE 474 Query: 818 LIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYKLLQDLFPKAA 875 L+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ L + K Sbjct: 475 LVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLK 534 Query: 876 ELYERVASNREHWTKVSHKFTIRGLPSNN 904 + + VA+NR W ++ K + S++ Sbjct: 535 PMLDSVATNRSKWEELHQKRLLASTASSS 563 Score = 37.0 bits (84), Expect = 0.086 Identities = 34/187 (18%), Positives = 79/187 (42%), Gaps = 24/187 (12%) Query: 218 DRDRKILQLCGELYD--LDASSLQLKVLQYLQQETRASRCCLLLVSE------------D 263 +R R +L++ +L++ D + K++ Q + RC +LL+ + + Sbjct: 26 ERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFE 85 Query: 264 NLQLSCKVIGDKVLGEEV---SFPLTGCLGQVVEDKKSIQLKDLTSEDVQ------QLQS 314 + C + E + S+ + E S L S+ Q + Sbjct: 86 LMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQ 145 Query: 315 MLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTL 374 + G ++++LCVP+ + + Q++ +A N+L+G F D D+ + + + + +T+ Sbjct: 146 ISGFHIRSVLCVPIWN-SNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTI 204 Query: 375 AFQKEQK 381 + + +K Sbjct: 205 MYDQVKK 211 >gi|116536083 phosphodiesterase 11A isoform 1 [Homo sapiens] Length = 489 Score = 303 bits (776), Expect = 5e-82 Identities = 167/456 (36%), Positives = 257/456 (56%), Gaps = 12/456 (2%) Query: 455 DQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELV 514 + IA VA+TG +NI DAY P F D +GF R++LC PI N N ++IGVA+++ Sbjct: 28 NNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVL 87 Query: 515 NKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDE 574 N+++G F D+ L AF I+CG+ I ++++Y +V ++ + +A +++ YH S E Sbjct: 88 NRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAE 147 Query: 575 YTKLLHDGIQPVAAI---DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPT 631 K I V+ + D +F F SL D A L M ++ + +KID T Sbjct: 148 VDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAMITAALRMFMELGMVQKFKIDYET 202 Query: 632 LARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDL 691 L R+ L V+K YR YHNW HAF+V + + + L ++EI A+ + C+CHDL Sbjct: 203 LCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDL 262 Query: 692 DHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRML 751 DHRGTNN+FQ S S LA LY + + +E HHF A+ IL + G NIF + S K+Y ++ Sbjct: 263 DHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLM 321 Query: 752 DLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQHHRLLLCLLMTSCDLSDQTKGWK 810 L++ ILATDL + + ++ G YD N K H + +LMT+CDL TK W+ Sbjct: 322 QLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWE 381 Query: 811 TTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDR-EKAYIPELQISFMEHIAMPIYKLLQ 868 +R++AEL+ EFF QGD E+ + P + DR K +P LQ+ +++ I MP+Y+ L Sbjct: 382 ISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALV 441 Query: 869 DLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 904 + K + + VA+NR W ++ K + S++ Sbjct: 442 KVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS 477 Score = 35.0 bits (79), Expect = 0.33 Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Query: 317 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 376 G ++++LCVP+ + + Q++ +A N+L+G F D D+ + + + + +T+ + Sbjct: 62 GFHIRSVLCVPIWN-SNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMY 120 Query: 377 QKEQK 381 + +K Sbjct: 121 DQVKK 125 >gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens] Length = 875 Score = 288 bits (737), Expect = 2e-77 Identities = 214/718 (29%), Positives = 362/718 (50%), Gaps = 46/718 (6%) Query: 218 DRDRKILQLCGELYD-LDASSLQLKVLQYLQQETRASRCCLLLVSED--NLQLSCKVIGD 274 D+ ++L+L ++ LD ++L K+ ++ A R L LV ED N + + D Sbjct: 147 DQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFD 206 Query: 275 KVLG---EEVSFPLT------GCLGQVVEDKKSIQLKDLTSEDVQ---QLQSMLGCELQA 322 G EEVS G +G V + + +KD ED + ++ + G + Q+ Sbjct: 207 VAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKD-AYEDPRFNAEVDQITGYKTQS 265 Query: 323 MLCVPVISRATDQVVALACAFNKLEGD--LFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQ 380 +LC+P I ++VV +A A NK G+ FT++DE + VL + ++ Sbjct: 266 ILCMP-IKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSL 324 Query: 381 KLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVF 438 Q LL +A +F + V+L++I + + C++F++D++ + + VF Sbjct: 325 LENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVF 384 Query: 439 DGGVVDDESYEIRIPADQGI-------AGHVATTGQILNIPDAYAHPLFYRGVDDSTGFR 491 + E + + A +V T + LNIPD F +++ Sbjct: 385 HMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVN 444 Query: 492 T---RNILCFPIKN-ENQEVIGVAELVNKINGPW-----FSKFDEDLATAFSIYCGISIA 542 R++LC PIKN + +VIGV +LVNK+ F++ DE AF I+CG+ I Sbjct: 445 QQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQ 504 Query: 543 HSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKL--LHDGIQPVAAIDSNFASFTYTP 600 ++ +Y+ V A + + E++ YH +++E +L L + P +A F+++ Sbjct: 505 NTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVP-SAQTLKITDFSFSD 563 Query: 601 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR-DPPYHNWMHAFSVSH 659 L + +T++ + M D+N + N+++ L R+ L VKK YR + YHNW HAF+ + Sbjct: 564 FELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQ 623 Query: 660 FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVM 719 + K ++ N L D+EI AL I+ + HDLDHRG NNS+ S+ LA LY S+M Sbjct: 624 CMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH--SIM 681 Query: 720 ERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHL-RIFKDLQKMAE 778 E HHF Q + ILN+ G I S ++Y+ L +++ ILATDLA ++ R + + + + Sbjct: 682 EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRK 741 Query: 779 VGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLE-KAMGNRP 837 ++ + L L +LMT+CDLS TK W ++IAEL+ EFF QGD E K + P Sbjct: 742 NQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEP 801 Query: 838 MEMMDREKA-YIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHK 894 ++M+REK IP +Q+ F++ I + +Y+ L + L + NR+ W ++ + Sbjct: 802 TDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 859 >gi|61744432 phosphodiesterase 5A isoform 3 [Homo sapiens] Length = 823 Score = 288 bits (737), Expect = 2e-77 Identities = 214/718 (29%), Positives = 362/718 (50%), Gaps = 46/718 (6%) Query: 218 DRDRKILQLCGELYD-LDASSLQLKVLQYLQQETRASRCCLLLVSED--NLQLSCKVIGD 274 D+ ++L+L ++ LD ++L K+ ++ A R L LV ED N + + D Sbjct: 95 DQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFD 154 Query: 275 KVLG---EEVSFPLT------GCLGQVVEDKKSIQLKDLTSEDVQ---QLQSMLGCELQA 322 G EEVS G +G V + + +KD ED + ++ + G + Q+ Sbjct: 155 VAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKD-AYEDPRFNAEVDQITGYKTQS 213 Query: 323 MLCVPVISRATDQVVALACAFNKLEGD--LFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQ 380 +LC+P I ++VV +A A NK G+ FT++DE + VL + ++ Sbjct: 214 ILCMP-IKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSL 272 Query: 381 KLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVF 438 Q LL +A +F + V+L++I + + C++F++D++ + + VF Sbjct: 273 LENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVF 332 Query: 439 DGGVVDDESYEIRIPADQGI-------AGHVATTGQILNIPDAYAHPLFYRGVDDSTGFR 491 + E + + A +V T + LNIPD F +++ Sbjct: 333 HMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVN 392 Query: 492 T---RNILCFPIKN-ENQEVIGVAELVNKINGPW-----FSKFDEDLATAFSIYCGISIA 542 R++LC PIKN + +VIGV +LVNK+ F++ DE AF I+CG+ I Sbjct: 393 QQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQ 452 Query: 543 HSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKL--LHDGIQPVAAIDSNFASFTYTP 600 ++ +Y+ V A + + E++ YH +++E +L L + P +A F+++ Sbjct: 453 NTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVP-SAQTLKITDFSFSD 511 Query: 601 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR-DPPYHNWMHAFSVSH 659 L + +T++ + M D+N + N+++ L R+ L VKK YR + YHNW HAF+ + Sbjct: 512 FELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQ 571 Query: 660 FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVM 719 + K ++ N L D+EI AL I+ + HDLDHRG NNS+ S+ LA LY S+M Sbjct: 572 CMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH--SIM 629 Query: 720 ERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHL-RIFKDLQKMAE 778 E HHF Q + ILN+ G I S ++Y+ L +++ ILATDLA ++ R + + + + Sbjct: 630 EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRK 689 Query: 779 VGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLE-KAMGNRP 837 ++ + L L +LMT+CDLS TK W ++IAEL+ EFF QGD E K + P Sbjct: 690 NQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEP 749 Query: 838 MEMMDREKA-YIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHK 894 ++M+REK IP +Q+ F++ I + +Y+ L + L + NR+ W ++ + Sbjct: 750 TDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 807 >gi|61744430 phosphodiesterase 5A isoform 2 [Homo sapiens] Length = 833 Score = 288 bits (737), Expect = 2e-77 Identities = 214/718 (29%), Positives = 362/718 (50%), Gaps = 46/718 (6%) Query: 218 DRDRKILQLCGELYD-LDASSLQLKVLQYLQQETRASRCCLLLVSED--NLQLSCKVIGD 274 D+ ++L+L ++ LD ++L K+ ++ A R L LV ED N + + D Sbjct: 105 DQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFD 164 Query: 275 KVLG---EEVSFPLT------GCLGQVVEDKKSIQLKDLTSEDVQ---QLQSMLGCELQA 322 G EEVS G +G V + + +KD ED + ++ + G + Q+ Sbjct: 165 VAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKD-AYEDPRFNAEVDQITGYKTQS 223 Query: 323 MLCVPVISRATDQVVALACAFNKLEGD--LFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQ 380 +LC+P I ++VV +A A NK G+ FT++DE + VL + ++ Sbjct: 224 ILCMP-IKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSL 282 Query: 381 KLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVF 438 Q LL +A +F + V+L++I + + C++F++D++ + + VF Sbjct: 283 LENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVF 342 Query: 439 DGGVVDDESYEIRIPADQGI-------AGHVATTGQILNIPDAYAHPLFYRGVDDSTGFR 491 + E + + A +V T + LNIPD F +++ Sbjct: 343 HMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVN 402 Query: 492 T---RNILCFPIKN-ENQEVIGVAELVNKINGPW-----FSKFDEDLATAFSIYCGISIA 542 R++LC PIKN + +VIGV +LVNK+ F++ DE AF I+CG+ I Sbjct: 403 QQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQ 462 Query: 543 HSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKL--LHDGIQPVAAIDSNFASFTYTP 600 ++ +Y+ V A + + E++ YH +++E +L L + P +A F+++ Sbjct: 463 NTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVP-SAQTLKITDFSFSD 521 Query: 601 RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR-DPPYHNWMHAFSVSH 659 L + +T++ + M D+N + N+++ L R+ L VKK YR + YHNW HAF+ + Sbjct: 522 FELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQ 581 Query: 660 FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVM 719 + K ++ N L D+EI AL I+ + HDLDHRG NNS+ S+ LA LY S+M Sbjct: 582 CMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH--SIM 639 Query: 720 ERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHL-RIFKDLQKMAE 778 E HHF Q + ILN+ G I S ++Y+ L +++ ILATDLA ++ R + + + + Sbjct: 640 EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRK 699 Query: 779 VGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLE-KAMGNRP 837 ++ + L L +LMT+CDLS TK W ++IAEL+ EFF QGD E K + P Sbjct: 700 NQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEP 759 Query: 838 MEMMDREKA-YIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHK 894 ++M+REK IP +Q+ F++ I + +Y+ L + L + NR+ W ++ + Sbjct: 760 TDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 817 >gi|223718037 phosphodiesterase 6B isoform 2 [Homo sapiens] Length = 853 Score = 283 bits (725), Expect = 4e-76 Identities = 217/806 (26%), Positives = 375/806 (46%), Gaps = 109/806 (13%) Query: 223 ILQLCGELYD-LDASSLQLKVLQYLQQETRASRCCLLLVSEDN--LQLSCKVIG---DKV 276 +L+L ++ + ++ + KVL+ L +A RC L + + N +L+ ++ D V Sbjct: 59 LLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSV 118 Query: 277 LGE-------EVSFPLT-GCLGQVVEDKKSIQLKDLTS--EDVQQLQSMLGCELQAMLCV 326 L + E+ FPL G +G V + KK + ++D+ + + + ML Sbjct: 119 LEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLAT 178 Query: 327 PVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCEC 386 P+++ VVA+ A NKL G FT EDE V ++ + L + CE Sbjct: 179 PIMNGK--DVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLK---IYHLSYLHNCET 233 Query: 387 ---QALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNE----------- 432 Q LL A +F L D+ + R N E SV LLD + Sbjct: 234 RRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVL 293 Query: 433 ------------------LVAKVFDGGVVDDESYEIRIPADQ--------GIAGHVATTG 466 + KV D + E ++ IP G+ +VA +G Sbjct: 294 MGESQPYSGPRTPDGREIVFYKVIDYILHGKEEIKV-IPTPSADHWALASGLPSYVAESG 352 Query: 467 QILNIPDAYAHPLF--YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK 524 I NI +A A +F G D +G+ +N+L PI N+ +E++GVA N+ +G F + Sbjct: 353 FICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDE 412 Query: 525 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHD--- 581 DE L + + + G S+ ++ Y K+N+ + R +A +M++YH+K DE +L Sbjct: 413 QDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRAR 472 Query: 582 -GIQPVAAIDSNFAS----------------FTYTPRSLPEDDTSMAILSMLQDMNFINN 624 G +P + F ++ E D + M ++ + Sbjct: 473 LGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRK 532 Query: 625 YKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFI 684 ++I L RF + KGYR YHNW H F+V+ + L +L +Y D+E FA+ Sbjct: 533 FQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVT 592 Query: 685 SCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSR 744 + +CHD+DHRGTNN +Q+ S++ LA L+ S S++ERHH +L+ NI+ + +R Sbjct: 593 AGLCHDIDHRGTNNLYQMKSQNPLAKLHGS--SILERHHLEFGKFLLSEETLNIYQNLNR 650 Query: 745 KDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQ-----------HHRLLL 793 + ++ ++ LM I+ATDLA + + QK+ + + +K+ +++ Sbjct: 651 RQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVM 710 Query: 794 CLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDREK-AYIPEL 851 ++MT+CDLS TK W+ K+A L+ EF+ QGDLE+ + +P+ MMDR K A +P+L Sbjct: 711 AMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKL 770 Query: 852 QISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDE 911 Q+ F++ + +YK + +++R+ +NR+ W ++ ++ + +L+ +E Sbjct: 771 QVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAK----VKALEEKEE 826 Query: 912 EYEVPDLDGTR------APINGCCSL 931 E V GT AP + C + Sbjct: 827 EERVAAKKGTEICNGGPAPKSSTCCI 852 Score = 77.4 bits (189), Expect = 6e-14 Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 29/255 (11%) Query: 385 ECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN----ELVAKVFD- 439 E ALL++ +++ ++ V+ + ++ L A+ CS+F+ Q EL ++F Sbjct: 55 ESTALLELVQDMQESINMERVVFK-VLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSV 113 Query: 440 --GGVVDD----ESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTR 493 V++D EI P D G+ GHVA T +++N+ D P F D+ T ++T+ Sbjct: 114 QPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTK 173 Query: 494 NILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEA 553 N+L PI N ++V+ V VNK+NGP+F+ DED+ + + + LY K+ Sbjct: 174 NMLATPIMN-GKDVVAVIMAVNKLNGPFFTSEDEDVFLKY-------LNFATLYLKIYHL 225 Query: 554 QYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRS-LPEDDTSMAI 612 Y + + ++ + +L I+ F YT R+ L + S+ + Sbjct: 226 SYLHNCETRRGQVLLWSANKVFEEL--------TDIERQFHKAFYTVRAYLNCERYSVGL 277 Query: 613 LSMLQDMNFINNYKI 627 L M ++ F + + + Sbjct: 278 LDMTKEKEFFDVWSV 292 >gi|105990537 phosphodiesterase 6B isoform 1 [Homo sapiens] Length = 854 Score = 282 bits (721), Expect = 1e-75 Identities = 208/764 (27%), Positives = 360/764 (47%), Gaps = 99/764 (12%) Query: 223 ILQLCGELYD-LDASSLQLKVLQYLQQETRASRCCLLLVSEDN--LQLSCKVIG---DKV 276 +L+L ++ + ++ + KVL+ L +A RC L + + N +L+ ++ D V Sbjct: 59 LLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSV 118 Query: 277 LGE-------EVSFPLT-GCLGQVVEDKKSIQLKDLTS--EDVQQLQSMLGCELQAMLCV 326 L + E+ FPL G +G V + KK + ++D+ + + + ML Sbjct: 119 LEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLAT 178 Query: 327 PVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCEC 386 P+++ VVA+ A NKL G FT EDE V ++ + L + CE Sbjct: 179 PIMNGK--DVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLK---IYHLSYLHNCET 233 Query: 387 ---QALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNE----------- 432 Q LL A +F L D+ + R N E SV LLD + Sbjct: 234 RRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVL 293 Query: 433 ------------------LVAKVFDGGVVDDESYEIRIPADQ--------GIAGHVATTG 466 + KV D + E ++ IP G+ +VA +G Sbjct: 294 MGESQPYSGPRTPDGREIVFYKVIDYILHGKEEIKV-IPTPSADHWALASGLPSYVAESG 352 Query: 467 QILNIPDAYAHPLF--YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK 524 I NI +A A +F G D +G+ +N+L PI N+ +E++GVA N+ +G F + Sbjct: 353 FICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDE 412 Query: 525 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHD--- 581 DE L + + + G S+ ++ Y K+N+ + R +A +M++YH+K DE +L Sbjct: 413 QDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRAR 472 Query: 582 -GIQPVAAIDSNFAS----------------FTYTPRSLPEDDTSMAILSMLQDMNFINN 624 G +P + F ++ E D + M ++ + Sbjct: 473 LGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRK 532 Query: 625 YKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFI 684 ++I L RF + KGYR YHNW H F+V+ + L +L +Y D+E FA+ Sbjct: 533 FQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVT 592 Query: 685 SCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSR 744 + +CHD+DHRGTNN +Q+ S++ LA L+ S S++ERHH +L+ NI+ + +R Sbjct: 593 AGLCHDIDHRGTNNLYQMKSQNPLAKLHGS--SILERHHLEFGKFLLSEETLNIYQNLNR 650 Query: 745 KDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQ-----------HHRLLL 793 + ++ ++ LM I+ATDLA + + QK+ + + +K+ +++ Sbjct: 651 RQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVM 710 Query: 794 CLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDREK-AYIPEL 851 ++MT+CDLS TK W+ K+A L+ EF+ QGDLE+ + +P+ MMDR K A +P+L Sbjct: 711 AMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKL 770 Query: 852 QISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKF 895 Q+ F++ + +YK + +++R+ +NR+ W ++ ++ Sbjct: 771 QVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEY 814 Score = 77.4 bits (189), Expect = 6e-14 Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 29/255 (11%) Query: 385 ECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN----ELVAKVFD- 439 E ALL++ +++ ++ V+ + ++ L A+ CS+F+ Q EL ++F Sbjct: 55 ESTALLELVQDMQESINMERVVFK-VLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSV 113 Query: 440 --GGVVDD----ESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTR 493 V++D EI P D G+ GHVA T +++N+ D P F D+ T ++T+ Sbjct: 114 QPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTK 173 Query: 494 NILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEA 553 N+L PI N ++V+ V VNK+NGP+F+ DED+ + + + LY K+ Sbjct: 174 NMLATPIMN-GKDVVAVIMAVNKLNGPFFTSEDEDVFLKY-------LNFATLYLKIYHL 225 Query: 554 QYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRS-LPEDDTSMAI 612 Y + + ++ + +L I+ F YT R+ L + S+ + Sbjct: 226 SYLHNCETRRGQVLLWSANKVFEEL--------TDIERQFHKAFYTVRAYLNCERYSVGL 277 Query: 613 LSMLQDMNFINNYKI 627 L M ++ F + + + Sbjct: 278 LDMTKEKEFFDVWSV 292 >gi|157364939 phosphodiesterase 6C [Homo sapiens] Length = 858 Score = 259 bits (661), Expect = 1e-68 Identities = 195/745 (26%), Positives = 342/745 (45%), Gaps = 97/745 (13%) Query: 241 KVLQYLQQETRASRCCLLLVSEDN--LQLSCKVIG--------DKVLG--EEVSFPLT-G 287 + LQ L +A RC + L N +++ +++ D ++G +EV FPL G Sbjct: 82 RALQRLAHLLQADRCSMFLCRSRNGIPEVASRLLDVTPTSKFEDNLVGPDKEVVFPLDIG 141 Query: 288 CLGQVVEDKKSIQLKDL--TSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNK 345 +G KK+ + D+ S + G + +L P++ +V+A+ A NK Sbjct: 142 IVGWAAHTKKTHNVPDVKKNSHFSDFMDKQTGYVTKNLLATPIV--VGKEVLAVIMAVNK 199 Query: 346 LEGDLFTDEDEHVIQHCFHYTSTVLT---STLAFQKEQKLKCECQALLQVAKNLFTHLDD 402 + F+ +DE V ++ S +L ++ + E + Q L+ A +F L D Sbjct: 200 VNASEFSKQDEEVFSKYLNFVSIILRLHHTSYMYNIESR---RSQILMWSANKVFEELTD 256 Query: 403 VSVLLQEIITEARNLSNAEICSVFLLDQNELVA------------------KVFDGGVVD 444 V + + R+ N E S+ LLD + K DG V+ Sbjct: 257 VERQFHKALYTVRSYLNCERYSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREVN 316 Query: 445 ---------DESYEIRI----PADQ-----GIAGHVATTGQILNIPDAYAHPLF--YRGV 484 EI++ PAD G+ +VA G I N+ +A A F +G Sbjct: 317 FYKIIDYILHGKEEIKVIPTPPADHWTLISGLPTYVAENGFICNMMNAPADEYFTFQKGP 376 Query: 485 DDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHS 544 D TG+ +N+L PI N+ ++++GVA N+ +G F + DE + + + G S+ ++ Sbjct: 377 VDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEYITETLTQFLGWSLLNT 436 Query: 545 LLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLH-------------DGIQPVAAIDS 591 Y K+N+ + R +A EM+M K + +E +L + Q VA + Sbjct: 437 DTYDKMNKLENRKDIAQEMLMNQTKATPEEIKSILKFQEKLNVDVIDDCEEKQLVAILKE 496 Query: 592 NFAS--------FTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGY 643 + F ++ L E + + ++N + +K+ L R+ V+KGY Sbjct: 497 DLPDPRSAELYEFRFSDFPLTEHGLIKCGIRLFFEINVVEKFKVPVEVLTRWMYTVRKGY 556 Query: 644 RDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVA 703 R YHNW H F+V + L L Y D+E FA+ + CHD+DHRGTNN +Q+ Sbjct: 557 RAVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMK 616 Query: 704 SKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDL 763 S S LA L+ S S++ERHH + +L NIF + +++ ++ ++ L I+ATDL Sbjct: 617 STSPLARLHGS--SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDL 674 Query: 764 AHHLRIFKDLQKMAE-----------VGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTT 812 A + + QK+ + + Y + +++ ++MT+CDLS TK W+ Sbjct: 675 ALYFKKRTMFQKIVDACEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDLSAITKPWEVQ 734 Query: 813 RKIAELIYKEFFSQGDLEK-AMGNRPMEMMDREKA-YIPELQISFMEHIAMPIYKLLQDL 870 ++A ++ EF+ QGDLE+ + +P+ MMDR K +P+LQ+ F++ + +YK Sbjct: 735 SQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTFVYKEFSRF 794 Query: 871 FPKAAELYERVASNREHWTKVSHKF 895 + + + +NR W ++ ++ Sbjct: 795 HKEITPMLSGLQNNRVEWKSLADEY 819 >gi|170650674 phosphodiesterase 6A [Homo sapiens] Length = 860 Score = 256 bits (653), Expect = 9e-68 Identities = 188/717 (26%), Positives = 328/717 (45%), Gaps = 90/717 (12%) Query: 257 LLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-GCLGQVVEDKKSIQLKDLTSED---VQQL 312 L V +D + C V+ D +E+ FPL G +G V KK + + T ED + Sbjct: 112 LFNVHKDAVLEDCLVMPD----QEIVFPLDMGIVGHVAHSKKIANVPN-TEEDEHFCDFV 166 Query: 313 QSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTS 372 + + + +L P+++ VVA+ A NK++G FT DE ++ ++ + ++ Sbjct: 167 DILTEYKTKNILASPIMNGK--DVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMK- 223 Query: 373 TLAFQKEQKLKCEC---QALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLD 429 + CE Q LL +F L D+ + + R N + SV LLD Sbjct: 224 --VYHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLD 281 Query: 430 QNELVA-----------------------------KVFDGGVVDDESYEI--RIPADQ-- 456 + KV D + E ++ P D Sbjct: 282 MTKQKEFFDVWPVLMGEVPPYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWA 341 Query: 457 ---GIAGHVATTGQILNIPDAYAHPLFYRGVD--DSTGFRTRNILCFPIKNENQEVIGVA 511 G+ +VA G I NI +A A F + D +G+ +N+L PI N+ +E++GVA Sbjct: 342 LVSGLPAYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVA 401 Query: 512 ELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVS 571 N+ +G F + DE L + + + G S+ + Y+ +N+ + R + +++ YH+K Sbjct: 402 TFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCD 461 Query: 572 DDEYTKLLHD----GIQPVAAIDSNFAS----------------FTYTPRSLPEDDTSMA 611 ++E K+L G +P + A F ++ L E + Sbjct: 462 NEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKC 521 Query: 612 ILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELT 671 + M ++ ++ + I L RF + KGYR YHNW H F+V + L +L Sbjct: 522 GIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLK 581 Query: 672 NYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAIL 731 Y D+E A+ + CHD+DHRGTNN +Q+ S++ LA L+ S S++ERHH +L Sbjct: 582 RYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGS--SILERHHLEFGKTLL 639 Query: 732 NTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQ---- 787 NIF + +R+ ++ + +M I+ATDLA + + QK+ + ++Q Sbjct: 640 RDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQ 699 Query: 788 -------HHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPME 839 +++ ++MT+CDLS TK W+ ++A L+ EF+ QGDLE+ + P+ Sbjct: 700 YMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIP 759 Query: 840 MMDREKA-YIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKF 895 MMDR KA +P+LQ+ F++ + +YK + + + + +NR+ W ++ ++ Sbjct: 760 MMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEY 816 Score = 67.8 bits (164), Expect = 5e-11 Identities = 81/302 (26%), Positives = 130/302 (43%), Gaps = 57/302 (18%) Query: 345 KLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS 404 KL DL ++ V +H S++ S + F L + Q LQ K +F + + Sbjct: 31 KLISDLLGAKEAAVDFSNYHSPSSMEESEIIFD----LLRDFQENLQTEKCIFNVMKKLC 86 Query: 405 VLLQEIITEARNLSNAEICSVFLLDQN----ELVAKVFD---GGVVDD----ESYEIRIP 453 LLQ A+ S+F+ EL ++F+ V++D EI P Sbjct: 87 FLLQ-----------ADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDQEIVFP 135 Query: 454 ADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAEL 513 D GI GHVA + +I N+P+ F VD T ++T+NIL PI N ++V+ + Sbjct: 136 LDMGIVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILASPIMN-GKDVVAIIMA 194 Query: 514 VNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDD 573 VNK++G F+K DE+ +L K +N A M +YH+ + Sbjct: 195 VNKVDGSHFTKRDEE----------------ILLKYLNFANL------IMKVYHLSYLHN 232 Query: 574 EYTK----LLHDG---IQPVAAIDSNFASFTYTPRS-LPEDDTSMAILSMLQDMNFINNY 625 T+ LL G + + I+ F YT R+ L D S+ +L M + F + + Sbjct: 233 CETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVW 292 Query: 626 KI 627 + Sbjct: 293 PV 294 >gi|223718019 phosphodiesterase 6B isoform 3 [Homo sapiens] Length = 575 Score = 249 bits (636), Expect = 8e-66 Identities = 142/474 (29%), Positives = 251/474 (52%), Gaps = 37/474 (7%) Query: 457 GIAGHVATTGQILNIPDAYAHPLF--YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELV 514 G+ +VA +G I NI +A A +F G D +G+ +N+L PI N+ +E++GVA Sbjct: 64 GLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFY 123 Query: 515 NKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDE 574 N+ +G F + DE L + + + G S+ ++ Y K+N+ + R +A +M++YH+K DE Sbjct: 124 NRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDE 183 Query: 575 YTKLLHD----GIQPVAAIDSNFAS----------------FTYTPRSLPEDDTSMAILS 614 +L G +P + F ++ E D + Sbjct: 184 IQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQ 243 Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M ++ + ++I L RF + KGYR YHNW H F+V+ + L +L +Y Sbjct: 244 MYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYY 303 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 D+E FA+ + +CHD+DHRGTNN +Q+ S++ LA L+ S S++ERHH +L+ Sbjct: 304 TDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGS--SILERHHLEFGKFLLSEE 361 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQ------- 787 NI+ + +R+ ++ ++ LM I+ATDLA + + QK+ + + +K+ Sbjct: 362 TLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLS 421 Query: 788 ----HHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMD 842 +++ ++MT+CDLS TK W+ K+A L+ EF+ QGDLE+ + +P+ MMD Sbjct: 422 LETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMD 481 Query: 843 REK-AYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKF 895 R K A +P+LQ+ F++ + +YK + +++R+ +NR+ W ++ ++ Sbjct: 482 RNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEY 535 Score = 31.2 bits (69), Expect = 4.7 Identities = 14/67 (20%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Query: 317 GCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAF 376 G ++ +L +P++++ +++V +A +N+ +G F ++DE +++ + + +T + Sbjct: 98 GWLIKNVLSMPIVNKK-EEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTY 156 Query: 377 QKEQKLK 383 K KL+ Sbjct: 157 DKMNKLE 163 >gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens] Length = 386 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 71 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 130 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 131 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 189 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 190 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 248 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 249 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 308 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 309 FIKFVLIPMFETVTKLFPMVEEI 331 >gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens] Length = 386 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 71 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 130 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 131 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 189 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 190 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 248 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 249 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 308 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 309 FIKFVLIPMFETVTKLFPMVEEI 331 >gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens] Length = 567 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 252 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 311 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 312 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 370 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 371 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 429 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 430 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 489 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 490 FIKFVLIPMFETVTKLFPMVEEI 512 >gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens] Length = 552 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 237 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 296 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 297 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 355 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 356 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 414 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 415 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 474 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 475 FIKFVLIPMFETVTKLFPMVEEI 497 >gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens] Length = 526 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 211 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 270 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 271 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 329 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 330 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 388 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 389 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 448 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 449 FIKFVLIPMFETVTKLFPMVEEI 471 >gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens] Length = 376 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 61 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 120 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 121 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 179 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 180 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 238 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 239 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 298 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 299 FIKFVLIPMFETVTKLFPMVEEI 321 >gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens] Length = 386 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 71 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 130 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 131 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 189 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 190 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 248 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 249 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 308 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 309 FIKFVLIPMFETVTKLFPMVEEI 331 >gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens] Length = 491 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 176 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 235 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 236 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 294 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 295 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 353 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 354 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 413 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 414 FIKFVLIPMFETVTKLFPMVEEI 436 >gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens] Length = 459 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 144 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 203 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 204 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 262 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 263 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 321 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 322 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 381 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 382 FIKFVLIPMFETVTKLFPMVEEI 404 >gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens] Length = 376 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 61 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 120 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 121 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 179 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 180 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 238 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 239 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 298 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 299 FIKFVLIPMFETVTKLFPMVEEI 321 >gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens] Length = 433 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 118 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 177 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 178 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 236 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 237 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 295 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 296 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 355 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 356 FIKFVLIPMFETVTKLFPMVEEI 378 >gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens] Length = 507 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 192 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 251 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 252 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 310 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 311 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 369 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 370 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 429 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 430 FIKFVLIPMFETVTKLFPMVEEI 452 >gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens] Length = 386 Score = 156 bits (395), Expect = 7e-38 Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 2/263 (0%) Query: 615 MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL 674 M D+ + ++ I+ TL R+ V YR+ P+HN+ H F V+ Y + L Sbjct: 71 MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF 130 Query: 675 EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH 734 +I L + +CHDLDH G NN++Q+ +++ LA Y ++ S +E HH A A IL Sbjct: 131 SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRY-NDISPLENHHCAVAFQILAEP 189 Query: 735 GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLC 794 CNIF + ++++ M +ILATD+A H I ++ E +D +N++H LL Sbjct: 190 ECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKM 248 Query: 795 LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS 854 +L+ CD+S++ + + + + +E+F Q D EK+ G MDR+K QI Sbjct: 249 ILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIG 308 Query: 855 FMEHIAMPIYKLLQDLFPKAAEL 877 F++ + +P+++ + LFP E+ Sbjct: 309 FIKFVLIPMFETVTKLFPMVEEI 331 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,868,549 Number of Sequences: 37866 Number of extensions: 1531215 Number of successful extensions: 6978 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 6654 Number of HSP's gapped (non-prelim): 142 length of query: 934 length of database: 18,247,518 effective HSP length: 112 effective length of query: 822 effective length of database: 14,006,526 effective search space: 11513364372 effective search space used: 11513364372 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.