Guide to the Human Genome
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Search of human proteins with 217272890

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217272890 palmitoyl-protein thioesterase 1 isoform 2
precursor [Homo sapiens]
         (203 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precurso...   425   e-119
gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor ...   337   5e-93
gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor...    65   3e-11
gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor...    65   3e-11
gi|30425524 hypothetical protein LOC339669 [Homo sapiens]              30   1.1  
gi|33239440 zinc finger protein, Y-linked isoform 1 [Homo sapiens]     29   2.4  
gi|223717965 zinc finger protein, Y-linked isoform 2 [Homo sapiens]    29   2.4  
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]                   29   2.4  
gi|34147522 chaperone, ABC1 activity of bc1 complex like precurs...    29   2.4  
gi|55953063 SET domain containing 4 isoform c [Homo sapiens]           29   2.4  
gi|13435127 TRAF3-interacting JNK-activating modulator [Homo sap...    29   2.4  
gi|8393013 SET domain containing 4 isoform a [Homo sapiens]            29   2.4  
gi|71061446 zinc finger protein, X-linked [Homo sapiens]               28   7.0  
gi|35493952 ubiquitin protein ligase E3B [Homo sapiens]                28   7.0  
gi|35493959 ubiquitin protein ligase E3B [Homo sapiens]                28   7.0  

>gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precursor
           [Homo sapiens]
          Length = 203

 Score =  425 bits (1092), Expect = e-119
 Identities = 203/203 (100%), Positives = 203/203 (100%)

Query: 1   MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGVFGLPRCPGESSHICDFI 60
           MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGVFGLPRCPGESSHICDFI
Sbjct: 1   MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGVFGLPRCPGESSHICDFI 60

Query: 61  RKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALK 120
           RKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALK
Sbjct: 61  RKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALK 120

Query: 121 KFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFL 180
           KFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFL
Sbjct: 121 KFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFL 180

Query: 181 ATEGDHLQLSEEWFYAHIIPFLG 203
           ATEGDHLQLSEEWFYAHIIPFLG
Sbjct: 181 ATEGDHLQLSEEWFYAHIIPFLG 203


>gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 306

 Score =  337 bits (863), Expect = 5e-93
 Identities = 168/185 (90%), Positives = 171/185 (92%), Gaps = 3/185 (1%)

Query: 22  RALQHLDPPAPLPLVIWHG---MGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV 78
           RA+    P  P+  +I  G    GVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV
Sbjct: 122 RAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV 181

Query: 79  QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS 138
           QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS
Sbjct: 182 QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS 241

Query: 139 EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI 198
           EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI
Sbjct: 242 EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI 301

Query: 199 IPFLG 203
           IPFLG
Sbjct: 302 IPFLG 306



 Score = 97.4 bits (241), Expect = 7e-21
 Identities = 48/77 (62%), Positives = 54/77 (70%), Gaps = 15/77 (19%)

Query: 1  MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGVFGLPRCPGESSHICDFI 60
          MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMG               D  
Sbjct: 1  MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMG---------------DSC 45

Query: 61 RKTLNAGAYSKVVQERL 77
             L+ GA  K+V++++
Sbjct: 46 CNPLSMGAIKKMVEKKI 62


>gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor
           [Homo sapiens]
          Length = 302

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%)

Query: 60  IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLM 117
           +R  L    YS   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN +
Sbjct: 157 MRSNLYRICYSPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFL 215

Query: 118 ALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQ 176
            +   V++   +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G 
Sbjct: 216 RVGHLVLIGGPDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGA 272

Query: 177 LV 178
           +V
Sbjct: 273 IV 274


>gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor
           [Homo sapiens]
          Length = 308

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%)

Query: 60  IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLM 117
           +R  L    YS   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN +
Sbjct: 163 MRSNLYRICYSPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFL 221

Query: 118 ALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQ 176
            +   V++   +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G 
Sbjct: 222 RVGHLVLIGGPDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGA 278

Query: 177 LV 178
           +V
Sbjct: 279 IV 280


>gi|30425524 hypothetical protein LOC339669 [Homo sapiens]
          Length = 195

 Score = 30.4 bits (67), Expect = 1.1
 Identities = 16/55 (29%), Positives = 30/55 (54%), Gaps = 1/55 (1%)

Query: 62  KTLNAGAYSKVVQERLVQ-AEYWHDPIKEDVYRNHSIFLADINQERGINESYKKN 115
           K+L   +Y+  V E+ V+  E+WH    +D+ R H     ++N ++ + E Y +N
Sbjct: 133 KSLMKASYTPEVIEKSVRDLEHWHGRKTDDLGRWHQKNAMNLNLQKALEEKYGEN 187


>gi|33239440 zinc finger protein, Y-linked isoform 1 [Homo sapiens]
          Length = 801

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 52  ESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES 111
           ES H+CD        G    +V + +V+AE   DP+  D+  +  + +AD   E  I+ S
Sbjct: 139 ESMHVCDI-------GHVEHMVHDSVVEAEIITDPLTSDIV-SEEVLVADCAPEAVIDAS 190


>gi|223717965 zinc finger protein, Y-linked isoform 2 [Homo sapiens]
          Length = 724

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 52  ESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES 111
           ES H+CD        G    +V + +V+AE   DP+  D+  +  + +AD   E  I+ S
Sbjct: 113 ESMHVCDI-------GHVEHMVHDSVVEAEIITDPLTSDIV-SEEVLVADCAPEAVIDAS 164


>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
          Length = 1079

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 150 KETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSE-EWFYAHI 198
           KET+   + S Y+  +  + EM+   QL  LA E  H QLSE E +YA I
Sbjct: 123 KETLKALQVSKYSLQKK-VSEMEQKVQLHLLAKEDYHKQLSEIEKYYATI 171


>gi|34147522 chaperone, ABC1 activity of bc1 complex like precursor
           [Homo sapiens]
          Length = 647

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 64  LNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFV 123
           L  GA ++V ++ L       DP  +      S FL++ N ER +    K    ALK   
Sbjct: 224 LGFGALAEVAKKSLRS----EDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQ 279

Query: 124 MVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLG 167
           M+   +D+ ++P  ++   F R  Q+ + +PL++      + LG
Sbjct: 280 MLSIQDDAFINPHLAKI--FERVRQSADFMPLKQMMKTLNNDLG 321


>gi|55953063 SET domain containing 4 isoform c [Homo sapiens]
          Length = 307

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 12/37 (32%), Positives = 22/37 (59%)

Query: 99  LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 135
           L   ++ RG+NES+K   + L+K++  +   DS + P
Sbjct: 16  LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52


>gi|13435127 TRAF3-interacting JNK-activating modulator [Homo
           sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 14/55 (25%), Positives = 28/55 (50%)

Query: 108 INESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYT 162
           + E+ ++ L+  +K V+++ L  +++   DS W G     + K  +   E  LYT
Sbjct: 181 LKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYT 235


>gi|8393013 SET domain containing 4 isoform a [Homo sapiens]
          Length = 440

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 12/37 (32%), Positives = 22/37 (59%)

Query: 99  LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 135
           L   ++ RG+NES+K   + L+K++  +   DS + P
Sbjct: 16  LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52


>gi|71061446 zinc finger protein, X-linked [Homo sapiens]
          Length = 805

 Score = 27.7 bits (60), Expect = 7.0
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 51  GESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGIN 109
           G+S H+ D +    + G    VV + +V+AE   DP+  DV  +  + +AD   E  I+
Sbjct: 136 GDSIHVSD-VGHVGHVGHVEHVVHDSVVEAEIVTDPLTTDVV-SEEVLVADCASEAVID 192


>gi|35493952 ubiquitin protein ligase E3B [Homo sapiens]
          Length = 1068

 Score = 27.7 bits (60), Expect = 7.0
 Identities = 13/65 (20%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 58  DFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLM 117
           +F+ K L    Y  +V    V   +    + + +  +HS+F + +++   ++  + KNL 
Sbjct: 776 EFVGKMLGKAVYEGIV----VDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLT 831

Query: 118 ALKKF 122
           ++K++
Sbjct: 832 SIKRY 836


>gi|35493959 ubiquitin protein ligase E3B [Homo sapiens]
          Length = 1068

 Score = 27.7 bits (60), Expect = 7.0
 Identities = 13/65 (20%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 58  DFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLM 117
           +F+ K L    Y  +V    V   +    + + +  +HS+F + +++   ++  + KNL 
Sbjct: 776 EFVGKMLGKAVYEGIV----VDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLT 831

Query: 118 ALKKF 122
           ++K++
Sbjct: 832 SIKRY 836


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,916,574
Number of Sequences: 37866
Number of extensions: 340172
Number of successful extensions: 792
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 779
Number of HSP's gapped (non-prelim): 18
length of query: 203
length of database: 18,247,518
effective HSP length: 97
effective length of query: 106
effective length of database: 14,574,516
effective search space: 1544898696
effective search space used: 1544898696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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