Search of human proteins with 216548152

Search of human proteins with 216548152

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|216548152 RNA pseudouridylate synthase domain containing 3
isoform 2 [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|216548152 RNA pseudouridylate synthase domain containing 3 is...   666   0.0  
gi|216548145 RNA pseudouridylate synthase domain containing 3 is...   656   0.0  
gi|221316663 RNA pseudouridylate synthase domain containing 4 is...    91   1e-18
gi|221316667 RNA pseudouridylate synthase domain containing 4 is...    90   3e-18
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]          35   0.095
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              33   0.47 
gi|239755238 PREDICTED: hypothetical protein [Homo sapiens]            30   4.0  
gi|239749762 PREDICTED: hypothetical protein XP_002347151 [Homo ...    30   4.0  
gi|239744021 PREDICTED: hypothetical protein XP_002343019 [Homo ...    30   4.0  
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            30   4.0  
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            30   4.0  
gi|23308689 RNA pseudouridylate synthase domain containing 2 [Ho...    30   4.0  
gi|110227615 echinoderm microtubule associated protein like 3 [H...    30   4.0  
gi|31982906 cingulin-like 1 [Homo sapiens]                             28   8.9  

>gi|216548152 RNA pseudouridylate synthase domain containing 3
           isoform 2 [Homo sapiens]
          Length = 336

 Score =  666 bits (1718), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ 60
           MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ
Sbjct: 1   MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ 60

Query: 61  PFAGLLPKNLSREELVDALRAAVVDRKGKPGELTLFSVLPELSQSLGLREQELQVVRASG 120
           PFAGLLPKNLSREELVDALRAAVVDRKGKPGELTLFSVLPELSQSLGLREQELQVVRASG
Sbjct: 61  PFAGLLPKNLSREELVDALRAAVVDRKGKPGELTLFSVLPELSQSLGLREQELQVVRASG 120

Query: 121 KESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHI 180
           KESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHI
Sbjct: 121 KESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHI 180

Query: 181 DGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQL 240
           DGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQL
Sbjct: 181 DGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQL 240

Query: 241 CPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLH 300
           CPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLH
Sbjct: 241 CPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLH 300

Query: 301 RLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ 336
           RLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ
Sbjct: 301 RLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ 336


>gi|216548145 RNA pseudouridylate synthase domain containing 3
           isoform 1 [Homo sapiens]
          Length = 351

 Score =  656 bits (1692), Expect = 0.0
 Identities = 336/351 (95%), Positives = 336/351 (95%), Gaps = 15/351 (4%)

Query: 1   MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ 60
           MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ
Sbjct: 1   MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQ 60

Query: 61  PFAGLLPKNLSREELVDALRAAVVDRKG---------------KPGELTLFSVLPELSQS 105
           PFAGLLPKNLSREELVDALRAAVVDRKG               KPGELTLFSVLPELSQS
Sbjct: 61  PFAGLLPKNLSREELVDALRAAVVDRKGPLVTLNKPQGLPVTGKPGELTLFSVLPELSQS 120

Query: 106 LGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPA 165
           LGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPA
Sbjct: 121 LGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPA 180

Query: 166 ASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPL 225
           ASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPL
Sbjct: 181 ASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPL 240

Query: 226 TVFSSQLQVHMVLQLCPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHL 285
           TVFSSQLQVHMVLQLCPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHL
Sbjct: 241 TVFSSQLQVHMVLQLCPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHL 300

Query: 286 TPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ 336
           TPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ
Sbjct: 301 TPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ 351


>gi|221316663 RNA pseudouridylate synthase domain containing 4
           isoform a [Homo sapiens]
          Length = 377

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 72/261 (27%), Positives = 126/261 (48%), Gaps = 32/261 (12%)

Query: 88  GKPG-ELTLFSVLPELSQSL-GLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTH 145
           G PG +L +  VLP L++ L G + + L +     KE++G+++L+     A ++Q+ F  
Sbjct: 119 GGPGVQLCITDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELF-- 176

Query: 146 ARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHIDG------VNLTVPVKAPSRKDIL- 198
             R ++    Y A+T  +P  S G +   +  +   G      + L+   +    K +  
Sbjct: 177 --RTRQVVKKYWAITVHVPMPSAGVVDIPIVEKEAQGQQQHHKMTLSPSYRMDDGKMVKV 234

Query: 199 ---EGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQL-CPVLGDHMYSARVG 254
                 +  ++ ++V+++    ALV+LQP+T    QL+VH+   L CP+LGDH YS    
Sbjct: 235 RRSRNAQVAVTQYQVLSSTLSSALVELQPITGIKHQLRVHLSFGLDCPILGDHKYS---- 290

Query: 255 TVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRLLLPGTRARDTPV 314
                      + N+   Q L    L++L L  S+A  +PLHLH  +L+LP   +    +
Sbjct: 291 -----------DWNRLAPQKLSVGTLKKLGLEQSKARYIPLHLHARQLILPALGSGKEEL 339

Query: 315 ELLAPLPPYFSRTLQCLGLRL 335
            L+  LP +F  +L  L L +
Sbjct: 340 NLVCKLPRFFVHSLHRLRLEM 360


>gi|221316667 RNA pseudouridylate synthase domain containing 4
           isoform b [Homo sapiens]
          Length = 346

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 70/251 (27%), Positives = 122/251 (48%), Gaps = 43/251 (17%)

Query: 88  GKPG-ELTLFSVLPELSQSL-GLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTH 145
           G PG +L +  VLP L++ L G + + L +     KE++G+++L+     A ++Q+ F  
Sbjct: 119 GGPGVQLCITDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELF-- 176

Query: 146 ARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTL 205
             R ++    Y A+T  +P  S G +               +P+       + +  +  +
Sbjct: 177 --RTRQVVKKYWAITVHVPMPSAGVVD--------------IPI-------VEKEAQVAV 213

Query: 206 SHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQL-CPVLGDHMYSARVGTVLGQRFLLP 264
           + ++V+++    ALV+LQP+T    QL+VH+   L CP+LGDH YS              
Sbjct: 214 TQYQVLSSTLSSALVELQPITGIKHQLRVHLSFGLDCPILGDHKYS-------------- 259

Query: 265 AENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYF 324
            + N+   Q L    L++L L  S+A  +PLHLH  +L+LP   +    + L+  LP +F
Sbjct: 260 -DWNRLAPQKLSVGTLKKLGLEQSKARYIPLHLHARQLILPALGSGKEELNLVCKLPRFF 318

Query: 325 SRTLQCLGLRL 335
             +L  L L +
Sbjct: 319 VHSLHRLRLEM 329


>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
          Length = 1236

 Score = 35.0 bits (79), Expect = 0.095
 Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 25/146 (17%)

Query: 200 GVKKTLSHFRVVATGSG-----CALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMYSARVG 254
           G+K  LS     ATGSG     C  +  Q  +  + Q  V + L+   +L D +  +R+G
Sbjct: 109 GLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDML--SRLG 166

Query: 255 TVLGQ------RFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRL-LLPGT 307
             LG         LLP + + P+  V   A+    HL  + +  L + L  H L  LPG 
Sbjct: 167 VPLGAFHASLLHCLLP-QLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGP 225

Query: 308 RARDTPVELLAPLPPYFSRTL-QCLG 332
           R          P  P   RTL QCLG
Sbjct: 226 R---------VPTSPTAIRTLIQCLG 242


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 32.7 bits (73), Expect = 0.47
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 22  WRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQPFAGLLP 67
           WR G G  P  E  G  ++  H   PRG  Q SGP    P+ G++P
Sbjct: 207 WRDGGGRGP-DELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMP 251


>gi|239755238 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 142

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 11  GRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQR-SGPLGDQ 60
           GR ++    SGW R   V  +P  AGFG  A  QR P G+    SG LG Q
Sbjct: 66  GRPLIDVKASGWLRRSPVGALP-GAGFGAHATGQRGPHGATPLFSGSLGLQ 115


>gi|239749762 PREDICTED: hypothetical protein XP_002347151 [Homo
           sapiens]
          Length = 142

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 11  GRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQR-SGPLGDQ 60
           GR ++    SGW R   V  +P  AGFG  A  QR P G+    SG LG Q
Sbjct: 66  GRPLIDVKASGWLRRSPVGALP-GAGFGAHATGQRGPHGATPLFSGSLGLQ 115


>gi|239744021 PREDICTED: hypothetical protein XP_002343019 [Homo
           sapiens]
          Length = 142

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 11  GRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQR-SGPLGDQ 60
           GR ++    SGW R   V  +P  AGFG  A  QR P G+    SG LG Q
Sbjct: 66  GRPLIDVKASGWLRRSPVGALP-GAGFGAHATGQRGPHGATPLFSGSLGLQ 115


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 25/199 (12%)

Query: 36   GFGTEARHQRQPRGSCQRSGPLGDQPFAGLLPKNLSREELVDALRAAVVDRKGKPGELTL 95
            G G   R   +PR  C     L   P  GLL   LS+                    L+L
Sbjct: 1007 GPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIY--------------SQSTLSL 1052

Query: 96   FSVLPELSQSLGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARR-AQRPTA 154
             +V  E   +LG++        +     SGL+  S  P +  R  +  ++A   A  P  
Sbjct: 1053 STVANEAHNNLGVKRP-----TSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEY 1107

Query: 155  TYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKT-LSHFRVVAT 213
            T   +    P+A   K      L H     L   V  P +  ILE ++K+  +HF ++  
Sbjct: 1108 TGPRLYKE-PSAKSNKFIIHNALSH---CCLAGKVNEPQKNRILEEIEKSKANHFLILFR 1163

Query: 214  GSGCALVQLQPLTVFSSQL 232
             S C    L  L+  + +L
Sbjct: 1164 DSSCQFRALYTLSGETEEL 1182


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 25/199 (12%)

Query: 36   GFGTEARHQRQPRGSCQRSGPLGDQPFAGLLPKNLSREELVDALRAAVVDRKGKPGELTL 95
            G G   R   +PR  C     L   P  GLL   LS+                    L+L
Sbjct: 1034 GPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIY--------------SQSTLSL 1079

Query: 96   FSVLPELSQSLGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARR-AQRPTA 154
             +V  E   +LG++        +     SGL+  S  P +  R  +  ++A   A  P  
Sbjct: 1080 STVANEAHNNLGVKRP-----TSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEY 1134

Query: 155  TYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKT-LSHFRVVAT 213
            T   +    P+A   K      L H     L   V  P +  ILE ++K+  +HF ++  
Sbjct: 1135 TGPRLYKE-PSAKSNKFIIHNALSH---CCLAGKVNEPQKNRILEEIEKSKANHFLILFR 1190

Query: 214  GSGCALVQLQPLTVFSSQL 232
             S C    L  L+  + +L
Sbjct: 1191 DSSCQFRALYTLSGETEEL 1209


>gi|23308689 RNA pseudouridylate synthase domain containing 2 [Homo
           sapiens]
          Length = 545

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 15/168 (8%)

Query: 111 QELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGK 170
           +EL  +    + +SG+++ +   +TA+  ++     R  Q      C V    P      
Sbjct: 265 KELHPLHRLDRLTSGVLMFA---KTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTC 321

Query: 171 IQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSS 230
            +  L + +  GV    P   P      E V + LS+          ++V+ +PLT  + 
Sbjct: 322 KEPILVVSYKVGVCRVDPRGKPC-----ETVFQRLSY------NGQSSVVRCRPLTGRTH 370

Query: 231 QLQVHMVLQLCPVLGDHMY-SARVGTVLGQRFLLPAENNKPQRQVLDE 277
           Q++VH+     P+L D +Y S   G   G+   +P  N +  R ++ E
Sbjct: 371 QIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYIPKTNEELLRDLVAE 418


>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
           sapiens]
          Length = 896

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 17/52 (32%), Positives = 29/52 (55%)

Query: 84  VDRKGKPGELTLFSVLPELSQSLGLREQELQVVRASGKESSGLVLLSSCPQT 135
           +D    PG+      L  LSQ L ++EQE+++V+A+  E+  L+ L   P +
Sbjct: 1   MDGAAGPGDGPAREALQSLSQRLRVQEQEMELVKAALAEALRLLRLQVPPSS 52


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 3/77 (3%)

Query: 57  LGDQPFAGLLPKNLSREELVDALRAAVVDRKG---KPGELTLFSVLPELSQSLGLREQEL 113
           L + P+A   P    ++ L+   +  V+DRK    KP  L  F   PEL Q     + EL
Sbjct: 103 LPENPYAQPSPIRNLKQPLLHEGKNGVLDRKDGSVKPSHLLNFQRHPELLQPYDPEKNEL 162

Query: 114 QVVRASGKESSGLVLLS 130
            +      ES+ L  L+
Sbjct: 163 NLQNHQPSESNWLKTLT 179


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,186,872
Number of Sequences: 37866
Number of extensions: 617447
Number of successful extensions: 1566
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1554
Number of HSP's gapped (non-prelim): 15
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.