Search of human proteins with 21614525

Search of human proteins with 21614525

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21614525 glypican 4 [Homo sapiens]
         (556 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21614525 glypican 4 [Homo sapiens]                                1131   0.0  
gi|5031719 glypican 6 precursor [Homo sapiens]                        722   0.0  
gi|167001141 glypican 1 precursor [Homo sapiens]                      471   e-133
gi|22749459 glypican 2 [Homo sapiens]                                 400   e-111
gi|4758464 glypican 5 [Homo sapiens]                                  201   1e-51
gi|4758462 glypican 3 [Homo sapiens]                                  169   8e-42
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]                     35   0.18 
gi|31083351 Sec6 protein [Homo sapiens]                                33   0.69 
gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo...    32   1.5  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    32   2.0  
gi|124244056 family with sequence similarity 123B [Homo sapiens]       30   5.8  
gi|209862861 hypothetical protein LOC9840 [Homo sapiens]               30   5.8  
gi|149363704 hypothetical protein LOC9840 [Homo sapiens]               30   5.8  
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    29   9.9  
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    29   9.9  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    29   9.9  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    29   9.9  
gi|110347437 latent transforming growth factor beta binding prot...    29   9.9  
gi|110347412 latent transforming growth factor beta binding prot...    29   9.9  
gi|110347431 latent transforming growth factor beta binding prot...    29   9.9  

>gi|21614525 glypican 4 [Homo sapiens]
          Length = 556

 Score = 1131 bits (2926), Expect = 0.0
 Identities = 556/556 (100%), Positives = 556/556 (100%)

Query: 1   MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKIC 60
           MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKIC
Sbjct: 1   MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKIC 60

Query: 61  PQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSL 120
           PQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSL
Sbjct: 61  PQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSL 120

Query: 121 NDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQY 180
           NDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQY
Sbjct: 121 NDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQY 180

Query: 181 HFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNP 240
           HFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNP
Sbjct: 181 HFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNP 240

Query: 241 TAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAE 300
           TAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAE
Sbjct: 241 TAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAE 300

Query: 301 RLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESA 360
           RLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESA
Sbjct: 301 RLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESA 360

Query: 361 FSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNE 420
           FSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNE
Sbjct: 361 FSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNE 420

Query: 421 DDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYN 480
           DDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYN
Sbjct: 421 DDCWNGKGKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYN 480

Query: 481 GNDVDFFDISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEKADSAGVRPGAQAYL 540
           GNDVDFFDISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEKADSAGVRPGAQAYL
Sbjct: 481 GNDVDFFDISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEKADSAGVRPGAQAYL 540

Query: 541 LTVFCILFLVMQREWR 556
           LTVFCILFLVMQREWR
Sbjct: 541 LTVFCILFLVMQREWR 556


>gi|5031719 glypican 6 precursor [Homo sapiens]
          Length = 555

 Score =  722 bits (1864), Expect = 0.0
 Identities = 352/546 (64%), Positives = 433/546 (79%), Gaps = 3/546 (0%)

Query: 9   LLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCCS 68
           +L  L +L +    A++K++SC EVR+ Y +KGF+  D P  EI G+HL+ICPQ  TCC+
Sbjct: 9   ILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCT 68

Query: 69  QEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTY 128
            EME+K S QSK +F+++V E  + ++  F SR+KKFDEFF+ELLENAEKSLNDMFV+TY
Sbjct: 69  TEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTY 128

Query: 129 GHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLE 188
           G LYMQNSE+F+DLF ELKRYY  GNVNLEEMLNDFWARLLERMF+L+N QYHF+++YLE
Sbjct: 129 GMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLE 188

Query: 189 CVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHAL 248
           CVSKYT+QLKPFGDVPRKLK+QVTRAF+AARTF QGL V  +V ++VS V+PT  C  AL
Sbjct: 189 CVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRAL 248

Query: 249 LKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNI 308
           +KM+YC +CRGL TV+PC NYC N+M+GCLANQ DLD EWN FIDAML+VAERLEGPFNI
Sbjct: 249 MKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNI 308

Query: 309 ESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPH 368
           ESVMDPIDVKIS+AIMNMQ+NS+QVS KVFQGCG PKP PA R +RS  E+ F+ RFRP+
Sbjct: 309 ESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPEN-FNTRFRPY 367

Query: 369 HPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKG 428
           +PEERPTTAAGTSLDRLVTD+KEKLK +KK WS+LP  +C DE + AG  NE++CWNG  
Sbjct: 368 NPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHS 427

Query: 429 KSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFD 488
           K+RYL  +  +GL NQ NNPEV VD ++PD  I +QIMALRVMT+K+KNAYNGNDV+F D
Sbjct: 428 KARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQD 487

Query: 489 ISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEK-ADSAGVRPGAQAYLLTVFCIL 547
            SDESSG GSGSGC    CP+EF++  T+      + +  DS+  + G      ++ CI+
Sbjct: 488 TSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLSWSLTCIV 547

Query: 548 FLVMQR 553
            L +QR
Sbjct: 548 -LALQR 552


>gi|167001141 glypican 1 precursor [Homo sapiens]
          Length = 558

 Score =  471 bits (1212), Expect = e-133
 Identities = 242/559 (43%), Positives = 355/559 (63%), Gaps = 21/559 (3%)

Query: 9   LLCTLAVLSAALLAAEL-KSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCC 67
           LLC  A L A        KS+SC EVR++Y +KGF+ +D P  EI+G+HL+ICPQG TCC
Sbjct: 10  LLCAAAALVACARGDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCC 69

Query: 68  SQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKT 127
           + EMEE  + +S  + ++ + +    LQA+ A++ + FD+ F+ LL ++E++L   F   
Sbjct: 70  TSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGA 129

Query: 128 YGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYL 187
           +G LY QN+  F+DL+ EL+ YY   N++LEE L +FWARLLER+F+ ++ Q    D+YL
Sbjct: 130 FGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYL 189

Query: 188 ECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHA 247
           +C+ K  E L+PFG+ PR+L+L+ TRAFVAAR+F QGL VA DVV KV+ V    +C+ A
Sbjct: 190 DCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRA 249

Query: 248 LLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFN 307
           ++K++YC+HC G+   +PC +YC N+++GCLANQ DLD EW N +D+M+++ ++  G   
Sbjct: 250 VMKLVYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSG 309

Query: 308 IESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRP 367
           +ESV+  +   +++AI  +QDN   ++ KV QGCG PK  P G            A    
Sbjct: 310 VESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRRGKLA---- 365

Query: 368 HHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGK 427
             P ERP +    +L++LV++ K +L+  + FW SLP  +C+ E+MA    ++D CWNG 
Sbjct: 366 --PRERPPSG---TLEKLVSEAKAQLRDVQDFWISLPGTLCS-EKMALSTASDDRCWNGM 419

Query: 428 GKSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFF 487
            + RYL  V G+GLANQ NNPEV+VD +KPD+ I +QIM L++MT+++++AYNGNDVDF 
Sbjct: 420 ARGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYNGNDVDFQ 479

Query: 488 DISDESSGEGSGSGCEYQQCPSEFDYNATD------HA--GKSANE-KADSAGVRPGAQA 538
           D SD+ SG GSG GC    C  +    ++       HA  G S  E +  SA   P    
Sbjct: 480 DASDDGSGSGSGDGCLDDLCSRKVSRKSSSSRTPLTHALPGLSEQEGQKTSAASCPQPPT 539

Query: 539 YLLTVFCILFLVMQR-EWR 556
           +LL +   L L + R  WR
Sbjct: 540 FLLPLLLFLALTVARPRWR 558


>gi|22749459 glypican 2 [Homo sapiens]
          Length = 579

 Score =  400 bits (1028), Expect = e-111
 Identities = 201/478 (42%), Positives = 305/478 (63%), Gaps = 6/478 (1%)

Query: 27  SKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSV 86
           ++SC+E R++  ++G++ N  P   I+G+HL++CPQ  TCCS E E++   +++  F+ +
Sbjct: 29  TRSCAETRQVLGARGYSLNLIPPALISGEHLRVCPQEYTCCSSETEQRLIRETEATFRGL 88

Query: 87  VSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVEL 146
           V +  + L    A+R++KFDEFF E+L  A+ SL  +F  +YG LY Q++ +F  LF  L
Sbjct: 89  VEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRL 148

Query: 147 KRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTE----QLKPFGD 202
           + +Y      L++ L DFWA+LLER+F L++ QY F  +YL C+S+        L+PFGD
Sbjct: 149 RDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGSLQPFGD 208

Query: 203 VPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVT 262
            PR+L+LQ+TR  VAAR F QGL    +VVS+   V  +  C+ AL+++I C  CRG+ +
Sbjct: 209 SPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPLCRGVPS 268

Query: 263 VKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDA 322
           + PC  +C N++RGCL+++G L+ +W N++D +L++A++L+GPF+ E   + I VKIS+ 
Sbjct: 269 LMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGLLILADKLQGPFSFELTAESIGVKISEG 327

Query: 323 IMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSL 382
           +M +Q+NS +VS +VFQ CGPP P+PA               +     EERPTTAAGT+L
Sbjct: 328 LMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTTAAGTNL 387

Query: 383 DRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNE-DDCWNGKGKSRYLFAVTGNGL 441
            RLV +++E+L + + FW+ L   VC D RMAA    E   CW G G+ RYL  V G   
Sbjct: 388 HRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPPVVGGSP 447

Query: 442 ANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSG 499
           A Q NNPE++VD S PD+   R+ + LR  T++MK A  G+D+D  D  +++SG G G
Sbjct: 448 AEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASGSGGG 505


>gi|4758464 glypican 5 [Homo sapiens]
          Length = 572

 Score =  201 bits (512), Expect = 1e-51
 Identities = 121/437 (27%), Positives = 225/437 (51%), Gaps = 14/437 (3%)

Query: 28  KSCSEVRRLYVSKGFNK-NDAPLHEINGDHLKIC-PQGSTCCSQEMEEKYSLQSKDDFKS 85
           ++C EVR+L+  +        P     G  L++C  +  TCC+++MEE+Y + ++ D + 
Sbjct: 28  QTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQ 87

Query: 86  VVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVE 145
            +    + L+ + +     F E  + L++ AE   + +F  TY ++ ++ +   ++ F +
Sbjct: 88  FLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTD 147

Query: 146 LKRYYVVGNVNLEEMLNDFWARLLERMFR-LVNSQYHFTD-EYLECVSKYTEQLKPFGDV 203
           +  Y    +VN EE +N F+  L   ++  L+N     +  EY EC+      + PFG++
Sbjct: 148 VGLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSECIRMARRDVSPFGNI 207

Query: 204 PRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTV 263
           P+++  Q+ R+ + +RTF Q L +  +V++    ++ + +C+ ALLKM YC HC+GL   
Sbjct: 208 PQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPHCQGLALT 267

Query: 264 KPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAI 323
           KPC  YC N+MRGCLA+  +L+  W+ +I ++  +++ + G ++I  V+    + ++DA+
Sbjct: 268 KPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIGHVLLNFHLLVNDAV 327

Query: 324 MNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSLD 383
           +    N  ++ ++V + CG P   P      S  +S      +  H  +  T  +  +L 
Sbjct: 328 LQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQS------KEKHGMKTTTRNSEETLA 381

Query: 384 RLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKG-KSRYLFAVTGNGLA 442
               +    L+  + F+  L   +C +E +AA +G    CWNG+     Y   V GNG+ 
Sbjct: 382 NRRKEFINSLRLYRSFYGGLADQLCANE-LAAADGL--PCWNGEDIVKSYTQRVVGNGIK 438

Query: 443 NQGNNPEVQVDTSKPDI 459
            Q  NPEV+V    P I
Sbjct: 439 AQSGNPEVKVKGIDPVI 455


>gi|4758462 glypican 3 [Homo sapiens]
          Length = 580

 Score =  169 bits (427), Expect = 8e-42
 Identities = 129/497 (25%), Positives = 234/497 (47%), Gaps = 42/497 (8%)

Query: 29  SCSEVRRLYVSKGFNKNDAPLHEINGDHLKIC-PQGSTCCSQEMEEKYSLQSKDDFKSVV 87
           +C +VR  +          P   + G  L++C P+G TCCS++MEEKY L ++ + + ++
Sbjct: 34  TCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLL 93

Query: 88  SEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELK 147
                 L+ +       F E F+ ++ +A+   N MF   Y  L  Q  E   + F ++ 
Sbjct: 94  QSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVS 153

Query: 148 RYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYH---FTDEYL---ECVSKYTEQLKPFG 201
            Y +  ++N+++M+N+    L + +F ++ +Q       D  L   EC+      LK FG
Sbjct: 154 LYILGSDINVDDMVNE----LFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFG 209

Query: 202 DVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLV 261
           + P+ +  QV+++    R F Q L +  +V++    +  +  C   L +M YCS+C+GL+
Sbjct: 210 NFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLM 269

Query: 262 TVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISD 321
            VKPC  YC+ +M+GC+A   ++D  W  +I ++  +   +   +++E+V+  +   I D
Sbjct: 270 MVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHD 329

Query: 322 AIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSAR--FRPHHPEERPTTAAG 379
           +I  +Q N+ +++  + + C   +       S    E  F  +   +  H E   T    
Sbjct: 330 SIQYVQKNAGKLTTTIGKLCAHSQQRQYR--SAYYPEDLFIDKKVLKVAHVEHEET---- 383

Query: 380 TSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKG-KSRYLFAVTG 438
             L     ++ +KLK    F+S+LP  +C+   +A    N+  CWNG+    RY      
Sbjct: 384 --LSSRRRELIQKLKSFISFYSALPGYICSHSPVAE---NDTLCWNGQELVERYSQKAAR 438

Query: 439 NGLANQGNNPEVQVDTSKPDILILRQIM--------ALRVMTSKMKNAYNGN-DVDFFDI 489
           NG+ NQ N  E+++   +P   ++ QI+         LR M+       + N D + F+ 
Sbjct: 439 NGMKNQFNLHELKMKGPEP---VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFES 495

Query: 490 SDESSGE-----GSGSG 501
            D    E     GSG G
Sbjct: 496 GDCGDDEDECIGGSGDG 512


>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
          Length = 248

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 45/186 (24%), Positives = 76/186 (40%), Gaps = 27/186 (14%)

Query: 86  VVSEQCNHLQAVFASRYKKFDEFFK--ELLENAEKSLNDMFVKTYGHLYMQNSELFKDLF 143
           +V E+ +  Q   A+  +K +E  K  +  E   K + +  +K    + +Q  +L +   
Sbjct: 58  LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117

Query: 144 V---------ELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVS--- 191
           +         E+ R  V+   +LE    +  A L E   R ++ Q    D+ L+C+S   
Sbjct: 118 IAEEADRKYEEVARKLVIIEGDLER--TEERAELAESRCREMDEQIRLMDQNLKCLSAAE 175

Query: 192 --------KYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQ 243
                   KY E++K   D   KLK   TRA  A R+ A+      D+  K+        
Sbjct: 176 EKYSQKEDKYEEEIKILTD---KLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHL 232

Query: 244 CTHALL 249
           CT  +L
Sbjct: 233 CTQRML 238


>gi|31083351 Sec6 protein [Homo sapiens]
          Length = 745

 Score = 33.1 bits (74), Expect = 0.69
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 70  EMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYG 129
           E   + + Q  +D K+ V   C      F SRYK   + +KE  E+     +      Y 
Sbjct: 433 EQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKE--EHLRNRQHPHCYVQYM 490

Query: 130 HLYMQNSELFKDLFVELKRYYVVGNV 155
              + N + FK+  V LKR Y+   V
Sbjct: 491 IAIINNCQTFKESIVSLKRKYLKNEV 516


>gi|20127486 mannose 6 phosphate receptor binding protein 1 [Homo
           sapiens]
          Length = 434

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 10/107 (9%)

Query: 293 DAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRI 352
           +A+L +++ L     +E+V   +D K+ +    +    +  +QK  QG     P P    
Sbjct: 267 EALLQLSQALS---LMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVE 323

Query: 353 SRSISESAFSARFRPHHPEERPT-TAAGTSLDRLVTDVKEKLKQAKK 398
           SR+++       FR    + + T T+ G+S+  L T+VK++++QA++
Sbjct: 324 SRALT------MFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARR 364


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 60/288 (20%), Positives = 113/288 (39%), Gaps = 48/288 (16%)

Query: 86   VVSEQCNHLQAVFASRYKKFDEFFKELL----ENAEK--SLNDMFVKTYGHLY-----MQ 134
            V  E+ + L A+F+S  K+  E  +EL+    E A+K   + D   K   HL+     M+
Sbjct: 2636 VKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMR 2695

Query: 135  N---------SELFKDLFVELKRYYVV---GNVNLEEMLNDFWARLLERMFRLVNSQYHF 182
            N         +EL +DL VE+++  ++    N  L   +  F       M  L NS+ H 
Sbjct: 2696 NETETAEERVAELARDL-VEMEQKLLMVTKENKGLTAQIQSFG----RSMSSLQNSRDHA 2750

Query: 183  TDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTA 242
             +E  E   KY   LK    +  +  L   R  + + T     +   + +S +  +N   
Sbjct: 2751 NEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLN--Q 2808

Query: 243  QCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNF-------IDAM 295
            Q      ++++ S       ++  YN   +  +   + Q + D  WN             
Sbjct: 2809 QLLSKDEQLLHLSS-----QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQ 2863

Query: 296  LMVAERLEGPFNIESVMDPIDVKISD------AIMNMQDNSVQVSQKV 337
               A+    P  ++S+   +    +D       + N+Q   +Q++Q++
Sbjct: 2864 RSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEI 2911


>gi|124244056 family with sequence similarity 123B [Homo sapiens]
          Length = 1135

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 8/89 (8%)

Query: 321  DAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGT 380
            D ++ + + S   S   F     P+  P G I+  I +     R RP HP+ +PT    +
Sbjct: 1050 DVLLPVDEPSCSSSSGGFSPSPLPQAKPVG-ITHGIPQLP---RVRPEHPQPQPTHYGPS 1105

Query: 381  SLDRLVTDVKEKLKQAKKFWSSLPSNVCN 409
            SLD      KE+ +Q     +S  S   N
Sbjct: 1106 SLDL----SKERAEQGASLATSYSSTAMN 1130


>gi|209862861 hypothetical protein LOC9840 [Homo sapiens]
          Length = 521

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 5/59 (8%)

Query: 343 PPKPLPAGRISRSISESAFSA--RFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKF 399
           P    P  R+ ++IS+       R RP  P   P      SLD++V +V +K+K+ K+F
Sbjct: 274 PEPQSPRDRLRKAISKMCLYTCPRDRPPPPHNTPKR---NSLDQVVLEVMDKVKEEKQF 329


>gi|149363704 hypothetical protein LOC9840 [Homo sapiens]
          Length = 521

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 5/59 (8%)

Query: 343 PPKPLPAGRISRSISESAFSA--RFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKF 399
           P    P  R+ ++IS+       R RP  P   P      SLD++V +V +K+K+ K+F
Sbjct: 274 PEPQSPRDRLRKAISKMCLYTCPRDRPPPPHNTPKR---NSLDQVVLEVMDKVKEEKQF 329


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 342 GPPKPLPAGRISRSISESAFSARFRPHHPEERPTTA 377
           GPPKP P G ++ + + ++   +  P  P  RP+ A
Sbjct: 279 GPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPA 314


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 29/163 (17%)

Query: 38   VSKGFNKNDAPLHE----INGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSVV------ 87
            V+K   K ++P H+    +N   L +C Q +  C Q  E+    +   D  +VV      
Sbjct: 4125 VNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEK 4184

Query: 88   -SEQCNHLQAVFASRYKKFDEFFKELL------ENAEKSLNDMFVKTYGHLYMQNSELFK 140
             + + ++L    A       E  K+L       + A + L D   K   HL + + EL K
Sbjct: 4185 FTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVK 4244

Query: 141  DLFVEL-----------KRYYVVGNVNLEEMLNDFWARLLERM 172
            +    L           KR   V   NLEE LN   +R  E M
Sbjct: 4245 EQTSHLEQRWFQLEDLIKRKIQVSVTNLEE-LNVVQSRFQELM 4286


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 42/163 (25%), Positives = 63/163 (38%), Gaps = 29/163 (17%)

Query: 38   VSKGFNKNDAPLHE----INGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSVV------ 87
            V+K   K ++P H+    +N   L +C Q +  C Q  E+    +   D  +VV      
Sbjct: 4196 VNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEK 4255

Query: 88   -SEQCNHLQAVFASRYKKFDEFFKELL------ENAEKSLNDMFVKTYGHLYMQNSELFK 140
             + + ++L    A       E  K+L       + A + L D   K   HL + + EL K
Sbjct: 4256 FTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVK 4315

Query: 141  DLFVEL-----------KRYYVVGNVNLEEMLNDFWARLLERM 172
            +    L           KR   V   NLEE LN   +R  E M
Sbjct: 4316 EQTSHLEQRWFQLEDLIKRKIQVSVTNLEE-LNVVQSRFQELM 4357


>gi|110347437 latent transforming growth factor beta binding protein 4
            isoform c [Homo sapiens]
          Length = 1557

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 11/14 (78%), Positives = 11/14 (78%)

Query: 495  GEGSGSGCEYQQCP 508
            GEG GSGC  QQCP
Sbjct: 1144 GEGWGSGCRIQQCP 1157


>gi|110347412 latent transforming growth factor beta binding protein 4
            isoform b [Homo sapiens]
          Length = 1587

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 11/14 (78%), Positives = 11/14 (78%)

Query: 495  GEGSGSGCEYQQCP 508
            GEG GSGC  QQCP
Sbjct: 1174 GEGWGSGCRIQQCP 1187


>gi|110347431 latent transforming growth factor beta binding protein 4
            isoform a [Homo sapiens]
          Length = 1624

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 11/14 (78%), Positives = 11/14 (78%)

Query: 495  GEGSGSGCEYQQCP 508
            GEG GSGC  QQCP
Sbjct: 1211 GEGWGSGCRIQQCP 1224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,473,295
Number of Sequences: 37866
Number of extensions: 916901
Number of successful extensions: 2841
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2811
Number of HSP's gapped (non-prelim): 28
length of query: 556
length of database: 18,247,518
effective HSP length: 107
effective length of query: 449
effective length of database: 14,195,856
effective search space: 6373939344
effective search space used: 6373939344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.