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Search of human proteins with 215276987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 436 e-123
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens] 416 e-116
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 386 e-108
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens] 386 e-108
gi|113417526 PREDICTED: similar to glutathione S-transferase alp... 260 6e-70
gi|169169045 PREDICTED: similar to glutathione S-transferase alp... 259 2e-69
gi|113418092 PREDICTED: similar to glutathione S-transferase alp... 259 2e-69
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens] 258 4e-69
gi|4504183 glutathione transferase [Homo sapiens] 84 1e-16
gi|7657457 prostaglandin-D synthase [Homo sapiens] 71 8e-13
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens] 68 5e-12
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens] 67 2e-11
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi... 63 2e-10
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens] 59 3e-09
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens] 59 4e-09
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens] 55 5e-08
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens] 52 4e-07
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens] 46 3e-05
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens] 46 3e-05
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens] 43 2e-04
gi|118600975 syntaxin binding protein 3 [Homo sapiens] 30 1.6
gi|15011844 selenophosphate synthetase 2 [Homo sapiens] 30 1.6
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept... 29 3.7
gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi... 29 3.7
gi|24797148 selenophosphate synthetase 1 [Homo sapiens] 29 3.7
gi|7656971 phosphonoformate immuno-associated protein 5 isoform ... 29 3.7
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] 28 6.2
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 28 6.2
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 28 6.2
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 28 6.2
>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
Length = 222
Score = 436 bits (1122), Expect = e-123
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
Length = 222
Score = 416 bits (1068), Expect = e-116
Identities = 211/222 (95%), Positives = 215/222 (96%)
Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMILLLP PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120
Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 386 bits (992), Expect = e-108
Identities = 197/222 (88%), Positives = 208/222 (93%)
Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI
Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120
Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
+ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL
Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222
>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
Length = 222
Score = 386 bits (992), Expect = e-108
Identities = 197/222 (88%), Positives = 206/222 (92%)
Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MAEKPKLHYSN RG MESIRWLLAAAGVE EEKF++SAEDLDKLRNDG L+FQQVPMVEI
Sbjct: 1 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
DGMKLVQTRAILNYIASKYNLYGKD+KE+ALIDMY EGI DL EMILLL QPEE+DAK
Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK 120
Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
AL++EK KNRYFPAFEKVLKSH QDYLVGNKLS ADIHLVEL YYVEELDSSLISSFPL
Sbjct: 121 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222
LKALKTRISNLPTVKKFLQPGS RKPPMDEKSLEE+RKIFRF
Sbjct: 181 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF 222
>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 260 bits (665), Expect = 6e-70
Identities = 142/210 (67%), Positives = 162/210 (77%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYIASKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIK 65
Query: 88 EKA---------LIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEK 138
E+A +DMYIEG A L E +L PEE+DAKLALI+E T + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221
PTVKKFLQPGS RK P+D K L+E+ KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 227
Score = 259 bits (661), Expect = 2e-69
Identities = 141/209 (67%), Positives = 161/209 (77%), Gaps = 16/209 (7%)
Query: 29 EFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKE 88
E E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYI SKYNL GKDIKE
Sbjct: 18 ESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKE 77
Query: 89 KA---------LIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKV 139
+A +DMYIEG A L E +L PEE+DAKLALI+E T + YFP FE V
Sbjct: 78 RAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETV 137
Query: 140 LKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNLP 192
LKSH QDYL+GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS LP
Sbjct: 138 LKSHEQDYLIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLP 197
Query: 193 TVKKFLQPGSPRKPPMDEKSLEESRKIFR 221
TVKKFLQPGS RK P+D K L+E+ KIF+
Sbjct: 198 TVKKFLQPGSLRKLPIDAKGLQEATKIFK 226
>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 259 bits (661), Expect = 2e-69
Identities = 141/210 (67%), Positives = 161/210 (76%), Gaps = 16/210 (7%)
Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIK 87
VE E KF++SA+DL+KLRND MFQQVPMVEIDGMKLVQTRAILNYI SKYNL GKDIK
Sbjct: 6 VESERKFLESAKDLEKLRNDESFMFQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIK 65
Query: 88 EKA---------LIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEK 138
E+A +DMYIEG A L E +L PEE+DAKLALI+E T + YFP FE
Sbjct: 66 ERAPYIWLFLSYRVDMYIEGRAGLSEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFET 125
Query: 139 VLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK-------ALKTRISNL 191
VLKSH QDY +GNKLS+ADIHLV+LLY+VEE DSSLIS+FP+LK ALK RIS L
Sbjct: 126 VLKSHEQDYFIGNKLSQADIHLVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKL 185
Query: 192 PTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221
PTVKKFLQPGS RK P+D K L+E+ KIF+
Sbjct: 186 PTVKKFLQPGSLRKLPIDAKGLQEATKIFK 215
>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
Length = 222
Score = 258 bits (658), Expect = 4e-69
Identities = 120/221 (54%), Positives = 173/221 (78%)
Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60
MA +PKLHY N RGRMES+RW+LAAAGVEF+E+F+++ E L KL++ +L+FQQVPMVEI
Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60
Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120
DGMKLVQTR+IL+YIA K+NL+GK++KE+ LIDMY+EG DL E++++ PF +P++Q +
Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120
Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180
+ + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S+FP
Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180
Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221
L+ ++SN+PT+K+FL+PGS +KPP DE + IFR
Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221
>gi|4504183 glutathione transferase [Homo sapiens]
Length = 210
Score = 84.0 bits (206), Expect = 1e-16
Identities = 59/193 (30%), Positives = 102/193 (52%), Gaps = 9/193 (4%)
Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQT 68
Y +RGR ++R LLA G ++E+ + + E + ++ Q+P + + L Q+
Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66
Query: 69 RAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE-QDAKLALIQEK 127
IL ++ LYGKD +E AL+DM +G+ DL + L ++ E +D + + +
Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126
Query: 128 TKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALK 185
K FE +L + G+ ++VG+++S AD +L++LL E L + +FPLL A
Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181
Query: 186 TRISNLPTVKKFL 198
R+S P +K FL
Sbjct: 182 GRLSARPKLKAFL 194
>gi|7657457 prostaglandin-D synthase [Homo sapiens]
Length = 199
Score = 70.9 bits (172), Expect = 8e-13
Identities = 52/197 (26%), Positives = 105/197 (53%), Gaps = 12/197 (6%)
Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65
KL Y N+RGR E IR++ A +++E+ I+ A D ++++ L F ++P++E+DG+ L
Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDGLTL 61
Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQ 125
Q+ AI Y+ +L G E+ +D ++ L + + P+++ ++QD K +
Sbjct: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD---TLDDFMSCFPWAE-KKQDVKEQMFN 117
Query: 126 E-KTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182
E T N P + L ++ G+++L+GN ++ AD + + L+ + P L
Sbjct: 118 ELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLV 175
Query: 183 ALKTRISNLPTVKKFLQ 199
L+ ++ +P V +++
Sbjct: 176 TLRKKVQAIPAVANWIK 192
>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
Length = 225
Score = 68.2 bits (165), Expect = 5e-12
Identities = 60/224 (26%), Positives = 89/224 (39%), Gaps = 22/224 (9%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59
L Y +IRG +IR LL +EEK E D R+ L F +P +
Sbjct: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+N+ G+ +EK +D+ + D ++ L +S
Sbjct: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD----- 123
Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK K +Y LK + G KL+ D ++L D
Sbjct: 124 -----HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKC 178
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218
+ FP LKA R L + +LQ K P++ K + K
Sbjct: 179 LDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222
>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
Length = 218
Score = 66.6 bits (161), Expect = 2e-11
Identities = 65/208 (31%), Positives = 98/208 (47%), Gaps = 28/208 (13%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y NIRG SIR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ + E IL F Q
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQ------------IREDILENQFMDSRMQL 111
Query: 119 AKLALIQ--EKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELD 171
AKL EK K Y A ++LK + Q + +G+K++ D ++L + +
Sbjct: 112 AKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFE 171
Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQ 199
S + +FP LK +R L + +++
Sbjct: 172 PSCLDAFPNLKDFISRFEGLEKISAYMK 199
>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
sapiens]
Length = 191
Score = 63.2 bits (152), Expect = 2e-10
Identities = 64/199 (32%), Positives = 94/199 (47%), Gaps = 28/199 (14%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y NIRG SIR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118
IDG K+ Q+ AIL YIA K+NL G+ KE+ + E IL F Q
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQ------------IREDILENQFMDSRMQL 111
Query: 119 AKLALIQ--EKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELD 171
AKL EK K Y A ++LK + Q + +G+K++ D ++L + +
Sbjct: 112 AKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFE 171
Query: 172 SSLISSFPLLKALKTRISN 190
S + +FP LK +R +
Sbjct: 172 PSCLDAFPNLKDFISRFEH 190
>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
Length = 218
Score = 58.9 bits (141), Expect = 3e-09
Identities = 53/201 (26%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+NL G+ +EK +D+ D+ + + +S P+ +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYS-PDFEKL 123
Query: 120 KLALIQE-KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178
K ++E T ++F F + + VG+K++ D ++L + + + +F
Sbjct: 124 KPEYLEELPTMMQHFSQF-----LGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAF 178
Query: 179 PLLKALKTRISNLPTVKKFLQ 199
P LK +R L + +++
Sbjct: 179 PNLKDFISRFEGLEKISAYMK 199
>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
Length = 218
Score = 58.5 bits (140), Expect = 4e-09
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 22/205 (10%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+NL G+ +EK +D+ D M L + PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK K +Y + LK + + + GNK++ D + ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +FP LK +R L + +++
Sbjct: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
Length = 195
Score = 55.1 bits (131), Expect = 5e-08
Identities = 52/189 (27%), Positives = 91/189 (48%), Gaps = 14/189 (7%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+NL G+ +EK +D+ D+ + + +S P+ +
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYS-PDFEKL 123
Query: 120 KLALIQE-KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178
K ++E T ++F F + + VG+K++ D ++L + + + +F
Sbjct: 124 KPEYLEELPTMMQHFSQF-----LGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAF 178
Query: 179 PLLKALKTR 187
P LK +R
Sbjct: 179 PNLKDFISR 187
>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
Length = 218
Score = 52.0 bits (123), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y +IRG +IR LL + EK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+NL G+ +EK +D+ + D M L+ P+
Sbjct: 65 DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMD-NHMELVRLCYDPD---- 119
Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174
EK K +Y + LK + + + G+K++ D ++L +
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKC 174
Query: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199
+ +F LK +R L + +++
Sbjct: 175 LDAFLNLKDFISRFEGLKKISAYMK 199
>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
Length = 181
Score = 45.8 bits (107), Expect = 3e-05
Identities = 48/158 (30%), Positives = 71/158 (44%), Gaps = 22/158 (13%)
Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59
L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P +
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119
K+ Q+ AIL YIA K+NL G+ +EK +D+ D M L + PE
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNK 152
EK K +Y + LK + + + GNK
Sbjct: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK 152
>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
Length = 216
Score = 45.8 bits (107), Expect = 3e-05
Identities = 50/194 (25%), Positives = 92/194 (47%), Gaps = 10/194 (5%)
Query: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPM 57
A KP L YS R +R LA G+++E I +D + + + +QVP
Sbjct: 3 AGKPIL-YSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPT 61
Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQP 114
++IDG+ + Q+ AI+ Y+ L +D K++A + M + IA + + L +
Sbjct: 62 LKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121
Query: 115 EEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174
++ +L Q F A E++L+S Y VG++++ AD+ LV + E L
Sbjct: 122 VGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180
Query: 175 ISSFPLLKALKTRI 188
+ +P + ++ R+
Sbjct: 181 -TPYPTISSINKRL 193
>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
Length = 161
Score = 42.7 bits (99), Expect = 2e-04
Identities = 36/139 (25%), Positives = 70/139 (50%), Gaps = 5/139 (3%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLL 109
+QVP ++IDG+ + Q+ AI+ Y+ L +D K++A + M + IA + + L
Sbjct: 2 KQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNL 61
Query: 110 PFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEE 169
+ ++ +L Q F A E++L+S Y VG++++ AD+ LV + E
Sbjct: 62 SVLKQVGEEMQLTWAQNAI-TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120
Query: 170 LDSSLISSFPLLKALKTRI 188
L + +P + ++ R+
Sbjct: 121 FKVDL-TPYPTISSINKRL 138
>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
Length = 592
Score = 30.0 bits (66), Expect = 1.6
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)
Query: 80 NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKV 139
N GKD + + D + A L E + S+P + +KLA + EK Y+ EK
Sbjct: 166 NAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKS 225
Query: 140 L---KSHGQDYLVGNKLSRADIHLVELLYYVEELD 171
L K+H Q ++ L EL + D
Sbjct: 226 LIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYD 260
>gi|15011844 selenophosphate synthetase 2 [Homo sapiens]
Length = 448
Score = 30.0 bits (66), Expect = 1.6
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ--PEEQDA 119
G+ LVQT + + G+ L D+Y GI + M++LL SQ EE+
Sbjct: 130 GLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLLSVSQSMSEEERE 189
Query: 120 KLALIQEK 127
K+ + K
Sbjct: 190 KVTPLMVK 197
>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
[Homo sapiens]
Length = 1068
Score = 28.9 bits (63), Expect = 3.7
Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 145 QDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKAL 184
+ YL +KLS+ I LV++L Y + LD+ L+ F L KAL
Sbjct: 620 EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLV-RFLLKKAL 658
>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
sapiens]
Length = 174
Score = 28.9 bits (63), Expect = 3.7
Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRI 188
F A E++L+S Y VG++++ AD+ LV + E L + +P + ++ R+
Sbjct: 97 FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPYPTISSINKRL 151
>gi|24797148 selenophosphate synthetase 1 [Homo sapiens]
Length = 392
Score = 28.9 bits (63), Expect = 3.7
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ---PEEQD 118
G+ LVQT + I + G+ L D+Y G+ + M++LL S E+D
Sbjct: 79 GLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERD 138
Query: 119 AKLALIQEKTKN 130
+ LI + K+
Sbjct: 139 KVMPLIIQGFKD 150
>gi|7656971 phosphonoformate immuno-associated protein 5 isoform 2
[Homo sapiens]
Length = 583
Score = 28.9 bits (63), Expect = 3.7
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 124 IQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIH 159
IQEKT N + P ++ G YL NK+ D+H
Sbjct: 46 IQEKTGNDWVPV--TIIDVRGHSYLQENKIKTTDLH 79
>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
Length = 240
Score = 28.1 bits (61), Expect = 6.2
Identities = 14/48 (29%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKEKALIDMYI 96
++VP ++ L ++ AIL Y+ KY + Y +D++ +A +D Y+
Sbjct: 52 KKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYL 99
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 28.1 bits (61), Expect = 6.2
Identities = 18/73 (24%), Positives = 32/73 (43%)
Query: 13 RGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 657 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 716
Query: 73 NYIASKYNLYGKD 85
+Y S Y Y K+
Sbjct: 717 SYDGSSYTTYMKE 729
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 28.1 bits (61), Expect = 6.2
Identities = 18/73 (24%), Positives = 32/73 (43%)
Query: 13 RGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 579 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 638
Query: 73 NYIASKYNLYGKD 85
+Y S Y Y K+
Sbjct: 639 SYDGSSYTTYMKE 651
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 28.1 bits (61), Expect = 6.2
Identities = 18/73 (24%), Positives = 32/73 (43%)
Query: 13 RGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAIL 72
RG++ LL VE + +K + + + Y++ VE+D +L +L
Sbjct: 599 RGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLL 658
Query: 73 NYIASKYNLYGKD 85
+Y S Y Y K+
Sbjct: 659 SYDGSSYTTYMKE 671
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,654,511
Number of Sequences: 37866
Number of extensions: 293428
Number of successful extensions: 868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 44
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.