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Search of human proteins with 21389385
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
(183 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 369 e-102
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 200 6e-52
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 131 4e-31
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 130 8e-31
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 128 2e-30
gi|21703367 Di-Ras2 [Homo sapiens] 119 1e-27
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 114 4e-26
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 114 4e-26
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 114 4e-26
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 114 4e-26
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 109 2e-24
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 107 4e-24
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 107 4e-24
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 107 6e-24
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 107 6e-24
gi|11967981 RAB17, member RAS oncogene family [Homo sapiens] 106 1e-23
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 106 1e-23
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 105 2e-23
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 104 4e-23
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 103 6e-23
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 103 6e-23
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 103 6e-23
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 102 1e-22
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 99 2e-21
gi|45592963 RAS-like, family 11, member A [Homo sapiens] 98 3e-21
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 97 6e-21
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 96 2e-20
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 94 7e-20
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 94 7e-20
gi|116812567 RAB25 [Homo sapiens] 93 1e-19
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 369 bits (946), Expect = e-102
Identities = 183/183 (100%), Positives = 183/183 (100%)
Query: 1 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD 60
MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
Sbjct: 1 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD 60
Query: 61 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120
TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
Sbjct: 61 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120
Query: 121 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC 180
ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
Sbjct: 121 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC 180
Query: 181 HLM 183
HLM
Sbjct: 181 HLM 183
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 200 bits (508), Expect = 6e-52
Identities = 96/184 (52%), Positives = 135/184 (73%), Gaps = 1/184 (0%)
Query: 1 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD 60
MP + RK+ ILGYR VGK+SL QFVEG+F + YDPT+ENT++K++T+ E+HL LVD
Sbjct: 1 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD 60
Query: 61 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120
TAGQDEYSI P ++ I ++GY+LVYSVTS+ SF+VI+ ++ KL + GK ++P++LVGNK
Sbjct: 61 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
Query: 121 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQ-ERR 179
DL ER + EGK LAESW A F+ESSA+ENQ +F ++I E +++ + Q +
Sbjct: 121 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS 180
Query: 180 CHLM 183
C +M
Sbjct: 181 CSVM 184
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 131 bits (329), Expect = 4e-31
Identities = 64/164 (39%), Positives = 104/164 (63%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R KVV+LG VGK++L QFV G F E YDPT+E+ Y K + + L ++DTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + +I G++LVYS+ + SFQ I+ + ++ +VP++LVGNK DL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
Query: 124 SPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
PEREV + EG+ LA+ WG FME+SA+ + +F ++++++
Sbjct: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 130 bits (326), Expect = 8e-31
Identities = 65/164 (39%), Positives = 103/164 (62%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R KVV+LG VGK++L QFV G F E YDPT+E+ Y K + + L ++DTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + +I G++LVYS+ + SFQ I+ + ++ +VPV+LVGNK DL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
Query: 124 SPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
EREV + EG+ LAE WG FME+SA+ + +F ++++++
Sbjct: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 128 bits (322), Expect = 2e-30
Identities = 68/177 (38%), Positives = 103/177 (58%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R KVV+LG VGK++L QFV G F E YDPT+E+ Y K + + L ++DTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + +I G++LVYS+ + SFQ I+ + ++ RVP++LVGNK DL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL 120
Query: 124 SPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC 180
EREV EGK LAE W FME+SA+ +F ++++++ G E C
Sbjct: 121 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCC 177
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 119 bits (298), Expect = 1e-27
Identities = 60/158 (37%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
+V + G VGK+SL +FV+G F E Y PTVE+TY ++++ K L + DT G ++
Sbjct: 9 RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQF 68
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTR-VPVVLVGNKADLSPE 126
+ I H ++LVYS+TS S + ++ +Y+++ E G +P++LVGNK D SP
Sbjct: 69 PAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPS 128
Query: 127 REVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVI 164
REVQ+ E + LA +W FME+SA+ N + +F +++
Sbjct: 129 REVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELL 166
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 4e-26
Identities = 65/184 (35%), Positives = 108/184 (58%), Gaps = 4/184 (2%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R K+V+LG VGK++L QFV+G F E YDPT+E++Y K V + + L ++DTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + ++ G+ LVYS+T+ +F ++ L +++ VP++LVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 124 SPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQERR 179
ER V +G+ LA W F+ESSA+ IF ++++I R VE +++
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 CHLM 183
C L+
Sbjct: 181 CLLL 184
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 4e-26
Identities = 65/184 (35%), Positives = 108/184 (58%), Gaps = 4/184 (2%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R K+V+LG VGK++L QFV+G F E YDPT+E++Y K V + + L ++DTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + ++ G+ LVYS+T+ +F ++ L +++ VP++LVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 124 SPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQERR 179
ER V +G+ LA W F+ESSA+ IF ++++I R VE +++
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 CHLM 183
C L+
Sbjct: 181 CLLL 184
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 4e-26
Identities = 65/184 (35%), Positives = 107/184 (58%), Gaps = 4/184 (2%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R K+V+LG VGK++L QFV+G F E YDPT+E++Y K V + + L ++DTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + ++ G+ LVYS+T+ +F ++ L +++ VP++LVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 124 SPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR--- 179
ER V +G+ LA W F+ESSA+ IF ++++I R G+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 180
Query: 180 CHLM 183
C L+
Sbjct: 181 CQLL 184
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 114 bits (286), Expect = 4e-26
Identities = 65/184 (35%), Positives = 107/184 (58%), Gaps = 4/184 (2%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R K+V+LG VGK++L QFV+G F E YDPT+E++Y K V + + L ++DTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
++++ + ++ G+ LVYS+T+ +F ++ L +++ VP++LVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 124 SPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR--- 179
ER V +G+ LA W F+ESSA+ IF ++++I R G+ R+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 180
Query: 180 CHLM 183
C L+
Sbjct: 181 CQLL 184
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 109 bits (272), Expect = 2e-24
Identities = 54/160 (33%), Positives = 93/160 (58%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
KV+++G VGK++L QF+ EF E Y+PT ++Y K V L +E + ++DTAGQ++Y
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
+ + ++ G++ V+S+T + SF +++ VP +LVGNK+DL +R
Sbjct: 76 AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKR 135
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
+V E K AE W ++E+SA+ +F +++EI
Sbjct: 136 QVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREI 175
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 107 bits (268), Expect = 4e-24
Identities = 57/172 (33%), Positives = 101/172 (58%), Gaps = 1/172 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
KV+++G VGK++L QF+ EF E Y+PT ++Y K V L +E + ++DTAGQ++Y
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSF-QVIESLYQKLHEGHGKTRVPVVLVGNKADLSPE 126
+ + ++ G++LV+S+T SF E Q L + ++P+++VGNK+DL
Sbjct: 76 AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEER 135
Query: 127 REVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQER 178
R+V E + AE WG ++E+SA+ +F +++EI + S +++
Sbjct: 136 RQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDK 187
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 107 bits (268), Expect = 4e-24
Identities = 57/168 (33%), Positives = 94/168 (55%)
Query: 5 RYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQ 64
R KVV+LG VGK+++ QF+ +F + +DPT+E+ Y V + + +L ++DTAGQ
Sbjct: 19 REYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQ 78
Query: 65 DEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLS 124
E++ + ++ G G+++ YSVT SFQ + + + +P+VLVGNK DL
Sbjct: 79 AEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLE 138
Query: 125 PEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVEN 172
R+V EG LA+ + F E+SA F +++EI + E+
Sbjct: 139 QFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKES 186
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 107 bits (267), Expect = 6e-24
Identities = 56/160 (35%), Positives = 96/160 (60%), Gaps = 1/160 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF+ I +++ VP+VLVGNK DL P R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
V + + LA S+G F+E+SA+ Q + F +++EI
Sbjct: 124 TVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREI 163
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 107 bits (267), Expect = 6e-24
Identities = 57/169 (33%), Positives = 92/169 (54%)
Query: 3 LVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTA 62
L R K+V+LG VGK+++ QF+ F E +DPT+E+ Y + + + +L ++DTA
Sbjct: 18 LSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTA 77
Query: 63 GQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKAD 122
GQ E++ + ++ G+++ YS+T SF + Q ++ PVVLVGNK+D
Sbjct: 78 GQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSD 137
Query: 123 LSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVE 171
L R+V EG LA + F E+SA +F +++EI R E
Sbjct: 138 LKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREIRRKE 186
>gi|11967981 RAB17, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 106 bits (265), Expect = 1e-23
Identities = 70/180 (38%), Positives = 104/180 (57%), Gaps = 10/180 (5%)
Query: 5 RYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTY-SKIVTLGKDEFHLHLVDTAG 63
R K+V+LG VGK+SLA ++V+ +F + PTV + +K+V +G L + DTAG
Sbjct: 18 RVFKLVLLGSGSVGKSSLALRYVKNDF-KSILPTVGCAFFTKVVDVGATSLKLEIWDTAG 76
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSF----QVIESLYQKLHEGHGKTRVPVVLVGN 119
Q++Y + + + G + +LVY +T SF Q ++ L ++LH G V V+LVGN
Sbjct: 77 QEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGE----VLVMLVGN 132
Query: 120 KADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR 179
K DLS EREV EGK+ A+S FME+SA+ N +F V QE+ + + GQ R
Sbjct: 133 KTDLSQEREVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQELLQRSDEEGQALR 192
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 106 bits (264), Expect = 1e-23
Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 1/162 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF+ I +++ VP+VLVGNK DL P R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIAR 169
V + + LA S+G F+E+SA+ Q F +++EI +
Sbjct: 124 TVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRK 165
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 105 bits (263), Expect = 2e-23
Identities = 56/173 (32%), Positives = 100/173 (57%), Gaps = 5/173 (2%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
++V++G VGK++L QF++ F YDPT+E++Y+K + L ++DTAGQ+E+
Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEF 75
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
+ ++ G++LV+SVT SF+ I +++ + P++L+GNKADL +R
Sbjct: 76 GAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQR 135
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC 180
+V EG++LA T+ME+SA+ F ++++ I + QE+ C
Sbjct: 136 QVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKF-----QEQEC 183
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 104 bits (260), Expect = 4e-23
Identities = 56/160 (35%), Positives = 96/160 (60%), Gaps = 1/160 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF I +++ VP+VLVGNK DL P R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
V + +LA+S+G F+E+SA+ Q + F +++EI
Sbjct: 124 TVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 103 bits (258), Expect = 6e-23
Identities = 54/160 (33%), Positives = 98/160 (61%), Gaps = 1/160 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF+ I +++ VP+VLVGNK DL+ R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-AR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
V++ + + LA S+G ++E+SA+ Q + F +++EI
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI 163
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 103 bits (258), Expect = 6e-23
Identities = 54/160 (33%), Positives = 98/160 (61%), Gaps = 1/160 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF+ I +++ VP+VLVGNK DL+ R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-AR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
V++ + + LA S+G ++E+SA+ Q + F +++EI
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI 163
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 103 bits (258), Expect = 6e-23
Identities = 55/158 (34%), Positives = 93/158 (58%), Gaps = 2/158 (1%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
+VV+ G VGK+SL +FV+G F + Y PT+E+TY ++++ K L + DT G ++
Sbjct: 9 RVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQF 68
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTR-VPVVLVGNKADLSPE 126
+ I H ++LV+SVTS S + + +Y+ + + G +PV+LVGNK D +
Sbjct: 69 PAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ETQ 127
Query: 127 REVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVI 164
REV E + +A+ W FME+SA+ N + +F +++
Sbjct: 128 REVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELL 165
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 102 bits (255), Expect = 1e-22
Identities = 51/164 (31%), Positives = 93/164 (56%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L QF++ F YDPT+E++Y+KI ++ L ++DTAGQ+E+
Sbjct: 31 KLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEF 90
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
+ ++ HG++LV+++ SF + L+ ++ + PVVLVGNKADL +R
Sbjct: 91 GAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQR 150
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVE 171
+V E S + E+SA+ F ++++ + + +
Sbjct: 151 QVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQ 194
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 99.0 bits (245), Expect = 2e-21
Identities = 51/147 (34%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L Q ++ F + YDPT+E++Y K V + + L ++DTAGQ+EY
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY 64
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G++ V+++ + SF+ I +++ VP+VLVGNK DL+ R
Sbjct: 65 SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-AR 123
Query: 128 EVQAVEGKKLAESWGATFMESSARENQ 154
V++ + + LA S+G ++E+SA+ Q
Sbjct: 124 TVESRQAQDLARSYGIPYIETSAKTRQ 150
>gi|45592963 RAS-like, family 11, member A [Homo sapiens]
Length = 242
Score = 98.2 bits (243), Expect = 3e-21
Identities = 58/184 (31%), Positives = 99/184 (53%), Gaps = 8/184 (4%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG---- 63
K+ +LG VGK+++ +F+ F Y+P YS++V + D+ L + DT G
Sbjct: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQI 88
Query: 64 QDEYSILPYSF---IIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK 120
QD + S + G++LVYS+T S+ I LYQ + + H ++ PV++VGNK
Sbjct: 89 QDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNK 148
Query: 121 ADLSPEREVQAVEGKKLAESWGATFMESSAREN-QLTQGIFTKVIQEIARVENSYGQERR 179
DL R+VQ +G +LA G+ F+E S EN + +F + +E++++ G+ RR
Sbjct: 149 GDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGERRR 208
Query: 180 CHLM 183
++
Sbjct: 209 ASII 212
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 97.4 bits (241), Expect = 6e-21
Identities = 55/159 (34%), Positives = 86/159 (54%), Gaps = 3/159 (1%)
Query: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
+R +VV++G VGK++L H++ G F Y PT+ENTY +++ LH+ D+
Sbjct: 35 IRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKS 94
Query: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKL--HEGHGKTRVPVVLVGNKA 121
D L I H +VLVYSVT + + +++ Y+ + +G+ + P+VLVGNK+
Sbjct: 95 GDGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKS 154
Query: 122 DLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIF 160
D REV +G A W FME SA+ + Q +F
Sbjct: 155 D-DTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELF 192
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 95.5 bits (236), Expect = 2e-20
Identities = 63/174 (36%), Positives = 94/174 (54%), Gaps = 4/174 (2%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+ I G VGK++L +F+ F YDPT+E+TY T+ + + ++DTAGQ++
Sbjct: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQED- 66
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
+I + G+VLVY +T SF+ + L L E V ++LVGNKADL R
Sbjct: 67 TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
Query: 128 EVQAVEGKKLAESWGATFMESSA--RENQLTQGIFTKVIQEIARVENSYGQERR 179
+V EG+KLA F E SA E +T+ IF ++ +E+ R G+ RR
Sbjct: 127 QVSTEEGEKLATELACAFYECSACTGEGNITE-IFYELCREVRRRRMVQGKTRR 179
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 94.0 bits (232), Expect = 7e-20
Identities = 52/163 (31%), Positives = 92/163 (56%), Gaps = 3/163 (1%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L QF + F YDPT+E++Y K + L ++DTAGQ+E+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G+++VYSVT SF+ ++ +Q + + P++LV NK DL R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARV 170
++ +GK++A ++E+SA++ L K ++ RV
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLN---VDKAFHDLVRV 174
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 94.0 bits (232), Expect = 7e-20
Identities = 52/163 (31%), Positives = 92/163 (56%), Gaps = 3/163 (1%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAGQDEY 67
K+V++G VGK++L QF + F YDPT+E++Y K + L ++DTAGQ+E+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 68 SILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPER 127
S + ++ G+++VYSVT SF+ ++ +Q + + P++LV NK DL R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 128 EVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARV 170
++ +GK++A ++E+SA++ L K ++ RV
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLN---VDKAFHDLVRV 174
>gi|116812567 RAB25 [Homo sapiens]
Length = 213
Score = 93.2 bits (230), Expect = 1e-19
Identities = 56/161 (34%), Positives = 91/161 (56%), Gaps = 2/161 (1%)
Query: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYS-KIVTLGKDEFHLHLVDTAGQDE 66
KVV++G VGKT+L +F EFS T+ +S + V LG + DTAG +
Sbjct: 14 KVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLER 73
Query: 67 YSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLSPE 126
Y + ++ G G +LV+ +T ++ V+E ++L++ H + + V+LVGNK+DLS
Sbjct: 74 YRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYD-HAEATIVVMLVGNKSDLSQA 132
Query: 127 REVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
REV E + AE+ G F+E+SA ++ + F V++EI
Sbjct: 133 REVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEI 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,359,343
Number of Sequences: 37866
Number of extensions: 254447
Number of successful extensions: 936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 185
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 544
Number of HSP's gapped (non-prelim): 221
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.