Guide to the Human Genome
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Search of human proteins with 21361507

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]
         (165 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]                   335   8e-93
gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]                   261   3e-70
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          67   9e-12
gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens]            62   3e-10
gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]              62   3e-10
gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens]              41   5e-04
gi|95113651 glutaredoxin 3 [Homo sapiens]                              34   0.066
gi|42516576 glutaredoxin 5 [Homo sapiens]                              31   0.43 
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]          29   1.6  
gi|50592994 thioredoxin [Homo sapiens]                                 28   3.6  
gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens]          28   3.6  
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s...    28   3.6  
gi|108860692 prolyl endopeptidase-like isoform D [Homo sapiens]        28   4.7  
gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens]     27   6.2  
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]     27   6.2  
gi|46275837 CCR4-NOT transcription complex, subunit 1 isoform b ...    27   8.0  
gi|42716275 CCR4-NOT transcription complex, subunit 1 isoform a ...    27   8.0  
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi...    27   8.0  
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi...    27   8.0  
gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapi...    27   8.0  

>gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]
          Length = 165

 Score =  335 bits (860), Expect = 8e-93
 Identities = 165/165 (100%), Positives = 165/165 (100%)

Query: 1   MNPRDKQVSRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQ 60
           MNPRDKQVSRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQ
Sbjct: 1   MNPRDKQVSRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQ 60

Query: 61  IQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGER 120
           IQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGER
Sbjct: 61  IQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGER 120

Query: 121 TVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ 165
           TVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ
Sbjct: 121 TVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ 165


>gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]
          Length = 164

 Score =  261 bits (666), Expect = 3e-70
 Identities = 128/137 (93%), Positives = 131/137 (95%)

Query: 29  SGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF 88
           +G+ G   +AA  MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF
Sbjct: 28  AGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF 87

Query: 89  HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL 148
           HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL
Sbjct: 88  HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL 147

Query: 149 PLVHQCYLKKSKRKEFQ 165
           PLVHQCYLKKSKRKEFQ
Sbjct: 148 PLVHQCYLKKSKRKEFQ 164


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 5/124 (4%)

Query: 33  GRTRSAARRMESNT----SSSLENLATAPVNQI-QETISDNCVVIFSKTSCSYCTMAKKL 87
           GR RSA       T     +   + ATA    + Q  I  + VVIFS+++C+ CT  KKL
Sbjct: 26  GRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKL 85

Query: 88  FHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKL 147
           F  + V Y V+ELD  E G   +  L ++  E  +P +FV    IGG   T + ++EG+L
Sbjct: 86  FKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRL 145

Query: 148 LPLV 151
             L+
Sbjct: 146 QKLL 149


>gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens]
          Length = 106

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 70  VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 126
           VV+F K +C YC  A+++   + +     + V++    + N+ QD L ++TG RTVPR+F
Sbjct: 15  VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74

Query: 127 VNGTFIGGATDTHRLHKEGKLLPLVHQ 153
           +    IGG +D   L + G+LL  + Q
Sbjct: 75  IGKDCIGGCSDLVSLQQSGELLTRLKQ 101


>gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]
          Length = 106

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 70  VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 126
           VV+F K +C YC  A+++   + +     + V++    + N+ QD L ++TG RTVPR+F
Sbjct: 15  VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74

Query: 127 VNGTFIGGATDTHRLHKEGKLLPLVHQ 153
           +    IGG +D   L + G+LL  + Q
Sbjct: 75  IGKDCIGGCSDLVSLQQSGELLTRLKQ 101


>gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens]
          Length = 290

 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/110 (21%), Positives = 56/110 (50%), Gaps = 7/110 (6%)

Query: 45  NTSSSLENLATAPVNQIQETISDNCVVIFS------KTSCSYCTMAKKLFHDMNVNYKVV 98
           +   +L N  T  + Q    +  + VVI++      +T+   C + +K+F +  V ++  
Sbjct: 114 SAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEK 173

Query: 99  ELDLL-EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKL 147
            + L  EYG +  +   +++   ++P +F++G ++GGA     +++ G+L
Sbjct: 174 NIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGEL 223


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 33.9 bits (76), Expect = 0.066
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 75  KTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGG 134
           +  C +     ++ +   V Y+    D+LE   + +  L   +   T P+++V G  +GG
Sbjct: 258 EAKCGFSKQILEILNSTGVEYET--FDILE-DEEVRQGLKAYSNWPTYPQLYVKGELVGG 314

Query: 135 ATDTHRLHKEGKLLPLV 151
                 L + G+LLP++
Sbjct: 315 LDIVKELKENGELLPIL 331


>gi|42516576 glutaredoxin 5 [Homo sapiens]
          Length = 157

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 10/28 (35%), Positives = 20/28 (71%)

Query: 121 TVPRIFVNGTFIGGATDTHRLHKEGKLL 148
           T+P++++NG F+GG     ++H+ G L+
Sbjct: 108 TIPQVYLNGEFVGGCDILLQMHQNGDLV 135


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 15/48 (31%), Positives = 25/48 (52%)

Query: 104 EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLV 151
           E G   +  L ++  E  +P +FV    IGG   T + ++EG+L  L+
Sbjct: 4   EDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLL 51


>gi|50592994 thioredoxin [Homo sapiens]
          Length = 105

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 70 VVIFSKTSCSYCTMAKKLFHDMNVNYKVV 98
          VV FS T C  C M K  FH ++  Y  V
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSEKYSNV 52


>gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens]
          Length = 669

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 11/71 (15%)

Query: 35  TRSAARRMESNTSSSLENLATAPVNQIQETISDNCVV-----------IFSKTSCSYCTM 83
           TRS   + +++T  +   L        QE  S +C+            +F+K+ C+ C+ 
Sbjct: 284 TRSIICKKDASTKKANVILPVESSKSFQEFYSTSCLSPCENNWNLKKGVFNKSRCTICSK 343

Query: 84  AKKLFHDMNVN 94
             ++ H+++VN
Sbjct: 344 LAEIRHEVSVN 354


>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
           sapiens]
          Length = 770

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 21/85 (24%), Positives = 35/85 (41%), Gaps = 6/85 (7%)

Query: 21  VALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSY 80
           V+ +    S    R +   R    ++ SS  + + A  NQI +   D C  + + TS S+
Sbjct: 488 VSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVPANTSASF 547

Query: 81  CTMAKKLFHDMNVNYKVVELDLLEY 105
                 L H   V   + + D L+Y
Sbjct: 548 ------LNHKQEVEKLLGKQDRLQY 566


>gi|108860692 prolyl endopeptidase-like isoform D [Homo sapiens]
          Length = 661

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%)

Query: 87  LFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGK 146
           LF  M  N KV++LD+      F+D          +  ++VN   IG A D+ R  K+GK
Sbjct: 339 LFFTMKRNTKVIDLDM------FKDHCVLFLKHSNL--LYVN--VIGLADDSVRSLKDGK 388

Query: 147 LLPL 150
           L+P+
Sbjct: 389 LVPM 392


>gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens]
          Length = 307

 Score = 27.3 bits (59), Expect = 6.2
 Identities = 17/56 (30%), Positives = 27/56 (48%)

Query: 9   SRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQET 64
           +R  P++D Y+ +      +S        +   +  +T SSLENL  AP+   QET
Sbjct: 114 NRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEALPESTDSSLENLPLAPLYPSQET 169


>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
          Length = 778

 Score = 27.3 bits (59), Expect = 6.2
 Identities = 17/56 (30%), Positives = 27/56 (48%)

Query: 9   SRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQET 64
           +R  P++D Y+ +      +S        +   +  +T SSLENL  AP+   QET
Sbjct: 114 NRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEALPESTDSSLENLPLAPLYPSQET 169


>gi|46275837 CCR4-NOT transcription complex, subunit 1 isoform b [Homo
            sapiens]
          Length = 1551

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 80   YCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVP 123
            YC     + H M   + + E   +EYG Q +D   KM G  T P
Sbjct: 971  YCQHLASISHFMQFPHHLQEY--IEYGQQSRDPPVKMQGSITTP 1012


>gi|42716275 CCR4-NOT transcription complex, subunit 1 isoform a [Homo
            sapiens]
          Length = 2376

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 80   YCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVP 123
            YC     + H M   + + E   +EYG Q +D   KM G  T P
Sbjct: 971  YCQHLASISHFMQFPHHLQEY--IEYGQQSRDPPVKMQGSITTP 1012


>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo
           sapiens]
          Length = 1137

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 26  IQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAK 85
           +QR  S    +   +R++  + SS+E  +    N   E+ SD+     ++      +M K
Sbjct: 617 VQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLK 676

Query: 86  KLFHDMNVNYKVVELDLLEY 105
           +       +Y+ +EL+LLE+
Sbjct: 677 RA-----PSYRTLELELLEW 691


>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo
           sapiens]
          Length = 1137

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 26  IQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAK 85
           +QR  S    +   +R++  + SS+E  +    N   E+ SD+     ++      +M K
Sbjct: 617 VQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLK 676

Query: 86  KLFHDMNVNYKVVELDLLEY 105
           +       +Y+ +EL+LLE+
Sbjct: 677 RA-----PSYRTLELELLEW 691


>gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo
           sapiens]
          Length = 717

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 26  IQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAK 85
           +QR  S    +   +R++  + SS+E  +    N   E+ SD+     ++      +M K
Sbjct: 197 VQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLK 256

Query: 86  KLFHDMNVNYKVVELDLLEY 105
           +       +Y+ +EL+LLE+
Sbjct: 257 RA-----PSYRTLELELLEW 271


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.131    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,840,172
Number of Sequences: 37866
Number of extensions: 215524
Number of successful extensions: 567
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 553
Number of HSP's gapped (non-prelim): 21
length of query: 165
length of database: 18,247,518
effective HSP length: 94
effective length of query: 71
effective length of database: 14,688,114
effective search space: 1042856094
effective search space used: 1042856094
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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