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Search of human proteins with 21361444
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361444 sialytransferase 7F [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361444 sialytransferase 7F [Homo sapiens] 697 0.0
gi|13569938 sialyltransferase 7E [Homo sapiens] 282 3e-76
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 219 3e-57
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 209 4e-54
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 194 1e-49
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens] 115 5e-26
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 73 3e-13
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 73 3e-13
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 72 7e-13
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 72 7e-13
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 69 8e-12
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 69 8e-12
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 63 4e-10
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 62 9e-10
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 60 4e-09
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 58 1e-08
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 52 6e-07
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 52 6e-07
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 52 6e-07
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 52 6e-07
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 52 6e-07
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 52 6e-07
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 52 6e-07
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 52 6e-07
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 52 6e-07
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 49 5e-06
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 49 6e-06
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 48 1e-05
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 47 2e-05
gi|192448440 sialyltransferase 7B [Homo sapiens] 44 2e-04
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 697 bits (1798), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MACSRPPSQCEPTSLPPGPPAGRRHLPLSRRRREMSSNKEQRSAVFVILFALITILILYS 60
MACSRPPSQCEPTSLPPGPPAGRRHLPLSRRRREMSSNKEQRSAVFVILFALITILILYS
Sbjct: 1 MACSRPPSQCEPTSLPPGPPAGRRHLPLSRRRREMSSNKEQRSAVFVILFALITILILYS 60
Query: 61 SNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGT 120
SNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGT
Sbjct: 61 SNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGT 120
Query: 121 KLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVF 180
KLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVF
Sbjct: 121 KLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVF 180
Query: 181 IFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKSHS 240
IFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKSHS
Sbjct: 181 IFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKSHS 240
Query: 241 WLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEH 300
WLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEH
Sbjct: 241 WLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEH 300
Query: 301 SRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT 333
SRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT
Sbjct: 301 SRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT 333
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 282 bits (721), Expect = 3e-76
Identities = 127/244 (52%), Positives = 174/244 (71%), Gaps = 2/244 (0%)
Query: 90 DGYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGN 149
DGY+ + +K L C C +V+SS HLL ++ G +I++ EC IRMNDAPT GY DVGN
Sbjct: 78 DGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGN 137
Query: 150 KTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKP-QGSLVRVIQRAGLVFP 208
+T+ RV+AHSS+ R+LR + +N + TVFIFWGP S M++ +G + + V P
Sbjct: 138 RTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLP 197
Query: 209 NMEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPN 268
++A+ ++ +M QFD+LF+ ETGKDR+ S++WLSTGWFTM IA+ELCD ++VYGMVPP+
Sbjct: 198 RLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPD 257
Query: 269 YCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFS 328
+C + P +PYHYYEP GPDEC Y+ +E RKG+HHRFITEKRVF +WA+ + I F
Sbjct: 258 FC-RDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFF 316
Query: 329 HPSW 332
P W
Sbjct: 317 QPDW 320
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 219 bits (558), Expect = 3e-57
Identities = 106/244 (43%), Positives = 156/244 (63%), Gaps = 4/244 (1%)
Query: 91 GYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNK 150
GY+ + + L C C IVS+S ++G K+G EI+R+ C RMN+APT GY DVG
Sbjct: 63 GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
Query: 151 TTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKP-QGSLVRVIQRAGLVFPN 209
T RVV+H+SV +L+ P F T+++ WGP M+K G + ++++ ++PN
Sbjct: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
Query: 210 MEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNY 269
+ Y + RM D +F+ ETGKDR +S S+LSTGWFT ++A++ C +HVYGM+ Y
Sbjct: 183 AQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTY 242
Query: 270 CSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSH 329
C + +++PYHYYE +G DEC Y +EH+ G HRFITEK+VF+ WA+ + I F+H
Sbjct: 243 C-KTEGYRKVPYHYYE-QGRDECDEYFLHEHAPYGG-HRFITEKKVFAKWAKKHRIIFTH 299
Query: 330 PSWT 333
P+WT
Sbjct: 300 PNWT 303
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 209 bits (531), Expect = 4e-54
Identities = 104/244 (42%), Positives = 151/244 (61%), Gaps = 4/244 (1%)
Query: 91 GYVPILGNKTLPSR-CHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGN 149
GY + K L C C +VSSS +LG+ LG EI+ AEC RMN APT G+ ADVG
Sbjct: 58 GYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQ 117
Query: 150 KTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKPQGS-LVRVIQRAGLVFP 208
++T RVV+H+SV +LR + + +T+++ WG M + G R + + ++P
Sbjct: 118 RSTLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYP 177
Query: 209 NMEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPN 268
++ Y + M D +F+ ETGK+R +S S+LSTGWFTM++A+ELC+ + VYGMV +
Sbjct: 178 GLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDS 237
Query: 269 YCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSRKGNHHRFITEKRVFSSWAQLYGITFS 328
YC ++ +PYHY+E DEC Y+ +E + + + HRFITEK VFS WA+ I F+
Sbjct: 238 YCREKSH-PSVPYHYFEKGRLDECQMYLAHEQAPR-SAHRFITEKAVFSRWAKKRPIVFA 295
Query: 329 HPSW 332
HPSW
Sbjct: 296 HPSW 299
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 194 bits (492), Expect = 1e-49
Identities = 94/217 (43%), Positives = 139/217 (64%), Gaps = 3/217 (1%)
Query: 117 LLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTP 176
+LG+ LG EI+ AEC RMN APT G+ ADVG ++T RVV+H+SV +LR + +
Sbjct: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
Query: 177 ETVFIFWGPPSKMQKPQGSLV-RVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDR 235
+T+++ WG M + G R + + ++P ++ Y + M D +F+ ETGK+R
Sbjct: 61 DTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNR 120
Query: 236 EKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTY 295
+S S+LSTGWFTM++A+ELC+ + VYGMV +YC ++ +PYHY+E DEC Y
Sbjct: 121 RQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH-PSVPYHYFEKGRLDECQMY 179
Query: 296 IQNEHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSW 332
+ +E + + + HRFITEK VFS WA+ I F+HPSW
Sbjct: 180 LAHEQAPR-SAHRFITEKAVFSRWAKKRPIVFAHPSW 215
>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
Length = 210
Score = 115 bits (288), Expect = 5e-26
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Query: 91 GYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNK 150
GY+ + + L C C IVS+S ++G K+G EI+R+ C RMN+APT GY DVG
Sbjct: 63 GYINVKTQEPLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRM 122
Query: 151 TTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSKMQKP-QGSLVRVIQRAGLVFPN 209
T RVV+H+SV +L+ P F T+++ WGP M+K G + ++++ ++PN
Sbjct: 123 TMIRVVSHTSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPN 182
Query: 210 MEAYAVSPGRMRQFDDLFRGETGKD 234
+ Y + RM D +F+ ETGKD
Sbjct: 183 AQIYVTTEKRMSYCDGVFKKETGKD 207
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 73.2 bits (178), Expect = 3e-13
Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 14/194 (7%)
Query: 80 PVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAP 139
P N +W +GY+P +T +C +VSS+ L ++LG EI+ + +R N AP
Sbjct: 159 PFNTSEW---EGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP 215
Query: 140 TTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGP-------PSKMQKP 192
T + DVG KTT R++ V R ++ + E + I W P P Q P
Sbjct: 216 TANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYN--EGILIVWDPSVYHSDIPKWYQNP 273
Query: 193 QGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIA 252
+ + + PN Y + P + D+ + + ++ + + S+G ++I
Sbjct: 274 DYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPP--SSGMLGIIIM 331
Query: 253 VELCDHVHVYGMVP 266
+ LCD V +Y +P
Sbjct: 332 MTLCDQVDIYEFLP 345
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 73.2 bits (178), Expect = 3e-13
Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 14/194 (7%)
Query: 80 PVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAP 139
P N +W +GY+P +T +C +VSS+ L ++LG EI+ + +R N AP
Sbjct: 159 PFNTSEW---EGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP 215
Query: 140 TTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGP-------PSKMQKP 192
T + DVG KTT R++ V R ++ + E + I W P P Q P
Sbjct: 216 TANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYN--EGILIVWDPSVYHSDIPKWYQNP 273
Query: 193 QGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIA 252
+ + + PN Y + P + D+ + + ++ + + S+G ++I
Sbjct: 274 DYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPP--SSGMLGIIIM 331
Query: 253 VELCDHVHVYGMVP 266
+ LCD V +Y +P
Sbjct: 332 MTLCDQVDIYEFLP 345
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 72.0 bits (175), Expect = 7e-13
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
P C +V S+ +L + LG EI+ + +R N APT GY DVGNKTT R++
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINS--- 346
Query: 162 FRVLRRP-QEFVNRT--PETVFIFWGPPSK-------MQKPQGSLVRVIQRAGLVFPNME 211
++L P F++ + + + + W P +KP +L + PN
Sbjct: 347 -QILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQP 405
Query: 212 AYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVP 266
Y + P + Q D+ + T + + + S+G+ ++I + +C VHVY +P
Sbjct: 406 FYILHPKFIWQLWDIIQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIP 458
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 72.0 bits (175), Expect = 7e-13
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
P C +V S+ +L + LG EI+ + +R N APT GY DVGNKTT R++
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINS--- 346
Query: 162 FRVLRRP-QEFVNRT--PETVFIFWGPPSK-------MQKPQGSLVRVIQRAGLVFPNME 211
++L P F++ + + + + W P +KP +L + PN
Sbjct: 347 -QILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQP 405
Query: 212 AYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVP 266
Y + P + Q D+ + T + + + S+G+ ++I + +C VHVY +P
Sbjct: 406 FYILHPKFIWQLWDIIQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIP 458
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 68.6 bits (166), Expect = 8e-12
Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 33/202 (16%)
Query: 76 RSRRPVNLKK-----WSITDGYV-PILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERA 129
R ++P NL + + G V P+L +++ C +C +V +S +L + GPEI+
Sbjct: 106 REKKPNNLNDTIKELFRVVPGNVDPMLEKRSVG--CRRCAVVGNSGNLRESSYGPEIDSH 163
Query: 130 ECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFW------ 183
+ +RMN APT G+ ADVG KTT+ +V S FR L + +T+ + W
Sbjct: 164 DFVLRMNKAPTAGFEADVGTKTTHHLVYPES-FRELGDNVSMILVPFKTIDLEWVVSAIT 222
Query: 184 -GPPSKMQKPQGSLVRVIQRAGLVF-PNMEAYAVSPGRMRQFDDLFRGETGKDREKSHSW 241
G S P + +RV Q L++ P Y FD+ +G +
Sbjct: 223 TGTISHTYIPVPAKIRVKQDKILIYHPAFIKYV--------FDNWLQGH--------GRY 266
Query: 242 LSTGWFTMVIAVELCDHVHVYG 263
STG +++ ++ +CD V +YG
Sbjct: 267 PSTGILSVIFSMHVCDEVDLYG 288
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 68.6 bits (166), Expect = 8e-12
Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 33/202 (16%)
Query: 76 RSRRPVNLKK-----WSITDGYV-PILGNKTLPSRCHQCVIVSSSSHLLGTKLGPEIERA 129
R ++P NL + + G V P+L +++ C +C +V +S +L + GPEI+
Sbjct: 106 REKKPNNLNDTIKELFRVVPGNVDPMLEKRSVG--CRRCAVVGNSGNLRESSYGPEIDSH 163
Query: 130 ECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFW------ 183
+ +RMN APT G+ ADVG KTT+ +V S FR L + +T+ + W
Sbjct: 164 DFVLRMNKAPTAGFEADVGTKTTHHLVYPES-FRELGDNVSMILVPFKTIDLEWVVSAIT 222
Query: 184 -GPPSKMQKPQGSLVRVIQRAGLVF-PNMEAYAVSPGRMRQFDDLFRGETGKDREKSHSW 241
G S P + +RV Q L++ P Y FD+ +G +
Sbjct: 223 TGTISHTYIPVPAKIRVKQDKILIYHPAFIKYV--------FDNWLQGH--------GRY 266
Query: 242 LSTGWFTMVIAVELCDHVHVYG 263
STG +++ ++ +CD V +YG
Sbjct: 267 PSTGILSVIFSMHVCDEVDLYG 288
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 62.8 bits (151), Expect = 4e-10
Identities = 58/217 (26%), Positives = 94/217 (43%), Gaps = 31/217 (14%)
Query: 83 LKKWSITDGYVPILGNKTLPS-RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTT 141
L+ +IT +P K + S RC +CV+V + L + LG I + + IR+N+AP
Sbjct: 94 LRVLAITSSSIP----KNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVA 149
Query: 142 GYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETVFIFWGPPSK----MQKPQGSLV 197
GY DVG+KTT R+ S V P+T+ + + ++
Sbjct: 150 GYEGDVGSKTTMRLFYPESA-----HFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKK 204
Query: 198 RVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDR---------EKSHSWLSTGWFT 248
RV R G + V+P ++R + F E D+ K +TG
Sbjct: 205 RV--RKGFWKQPPLIWDVNPKQIRILNPFFM-EIAADKLLSLPMQQPRKIKQKPTTGLLA 261
Query: 249 MVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYE 285
+ +A+ LCD VH+ G P+ +++ + HYYE
Sbjct: 262 ITLALHLCDLVHIAGFGYPDAYNKKQTI-----HYYE 293
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 61.6 bits (148), Expect = 9e-10
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 23/193 (11%)
Query: 108 CVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVV-------AHSS 160
C +V +S L G++ G EI++++ R N APT + DVG KT +++
Sbjct: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
Query: 161 VFRVLRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRV-----IQRAGLVFPNMEAYAV 215
+ + R F++ I W P+ ++ R ++ G ++
Sbjct: 222 LLTIQDRNNFFLSLKKLDGAILW-IPAFFFHTSATVTRTLVDFFVEHRG----QLKVQLA 276
Query: 216 SPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPR 275
PG + Q + + K++ S LSTG +A +C+ +H+YG P +
Sbjct: 277 WPGNIMQHVNRY----WKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF--DPNT 330
Query: 276 LQRMPYHYYEPKG 288
+ +PYHYY+ KG
Sbjct: 331 REDLPYHYYDKKG 343
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 59.7 bits (143), Expect = 4e-09
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 9/162 (5%)
Query: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
P +C +C +V +S +L G+ G +++ +RMN APT G+ DVG++TT+ + S
Sbjct: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESA 205
Query: 162 FRVLRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMR 221
+ L FV + + + W S + Q ++ L + +P +
Sbjct: 206 -KNLPANVSFVLVPFKVLDLLW-IASALSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFK 263
Query: 222 QFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYG 263
D + G+ + STG + A+ +CD V+VYG
Sbjct: 264 YIHDRWTEHHGR-------YPSTGMLVLFFALHVCDEVNVYG 298
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 58.2 bits (139), Expect = 1e-08
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
P C +V S+ +L + LG EI+ + +R N APT GY DVGNKTT R++
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINS--- 346
Query: 162 FRVLRRP-QEFVNRT--PETVFIFWGPPSK-------MQKPQGSLVRVIQRAGLVFPNME 211
++L P F++ + + + + W P +KP +L + PN
Sbjct: 347 -QILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQP 405
Query: 212 AYAVSPGRMRQFDDLFRGET 231
Y + P + Q D+ + T
Sbjct: 406 FYILHPKFIWQLWDIIQENT 425
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/51 (45%), Positives = 32/51 (62%)
Query: 105 CHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRV 155
C +CV++ S L G +LG + + + IR+N AP GYS VGNKTT R+
Sbjct: 169 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRM 219
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/51 (45%), Positives = 32/51 (62%)
Query: 105 CHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRV 155
C +CV++ S L G +LG + + + IR+N AP GYS VGNKTT R+
Sbjct: 192 CRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRM 242
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 194 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 250
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 251 AMQRPEQY 258
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 140 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 196
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 197 AMQRPEQY 204
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 210 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 266
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 267 AMQRPEQY 274
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 156 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 212
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 213 AMQRPEQY 220
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 171 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 227
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 228 AMQRPEQY 235
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 225 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 281
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 282 AMQRPEQY 289
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 52.4 bits (124), Expect = 6e-07
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 104 RCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFR 163
RC +C+IV + L LG I+ + +R+N AP G+ DVG+KTT R+
Sbjct: 156 RCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEG--- 212
Query: 164 VLRRPQEF 171
++RP+++
Sbjct: 213 AMQRPEQY 220
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 49.3 bits (116), Expect = 5e-06
Identities = 22/58 (37%), Positives = 34/58 (58%)
Query: 105 CHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVF 162
C +CV+V + L LG +I+ + IRMN+ P G+ +VG +TT+R+ SVF
Sbjct: 115 CKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVF 172
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 48.9 bits (115), Expect = 6e-06
Identities = 68/258 (26%), Positives = 105/258 (40%), Gaps = 31/258 (12%)
Query: 40 EQRSAVFVILFALITILILYSSNSANEVFHYGSLRGRSRRPVNLKK--WSITDGYVPILG 97
E R + L A + ++ SS +V HY R RR +N+ S+ P+
Sbjct: 80 EIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDR---RRTLNISHDLHSLLPEVSPMKN 136
Query: 98 NKTLPSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVA 157
R C +V +S LL ++ G EI+ IR N AP ++ADVG K+ + +
Sbjct: 137 R-----RFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMN 191
Query: 158 HSSV------FRVLRRPQEFVNR-TPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNM 210
S V FR ++FV+R + + W P + +G V L+ N
Sbjct: 192 PSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMV---KGGEKHVEWVNALILKNK 248
Query: 211 EAYAVSPGRMRQFDDLFRGE--TGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVP-P 267
+ +R + RG T K K STG +A CD +H+YG P P
Sbjct: 249 LKVRTAYPSLRLIHAV-RGYWLTNKVPIKRP---STGLLMYTLATRFCDEIHLYGFWPFP 304
Query: 268 NYCSQRPRLQRMPYHYYE 285
+ + + YHYY+
Sbjct: 305 KDLNGK----AVKYHYYD 318
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/219 (24%), Positives = 86/219 (39%), Gaps = 46/219 (21%)
Query: 106 HQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTG-YSADVGNKTTYRVVAHSSVFRV 164
+QC +V + L + G EI++++ R N PTTG S DVG+KT
Sbjct: 184 NQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKT------------- 230
Query: 165 LRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFD 224
V P + + +G +++ + + I G F + A++ F
Sbjct: 231 -----NLVTINPSIITLKYG---NLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFK 282
Query: 225 DLFRGETGKDREK------------SHSW---------LSTGWFTMVIAVELCDHVHVYG 263
+ E K R+K + W LSTG +AVELC +V +YG
Sbjct: 283 VYYTLEESKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYG 342
Query: 264 MVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSR 302
P S+ + +HYY+ K P + E+S+
Sbjct: 343 FWP---FSKTVEDIPVSHHYYDNKLPKHGFHQMPKEYSQ 378
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 47.0 bits (110), Expect = 2e-05
Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 16/186 (8%)
Query: 107 QCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTG-YSADVGNKTTYRVVAHSSVFR-- 163
+C +V + L + G +I+ A +R N P + Y+ DVG+K+ V A+ S+ R
Sbjct: 137 KCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQL-VTANPSIIRQR 195
Query: 164 ---VLRRPQEFV-NRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGR 219
+L + FV N + P M+ +RV V N +P
Sbjct: 196 FQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNF 255
Query: 220 MRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRM 279
+R G+ K R LSTG F + A+ LC+ V +YG P S Q +
Sbjct: 256 LRSI-----GKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWP---FSVNMHEQPI 307
Query: 280 PYHYYE 285
+HYY+
Sbjct: 308 SHHYYD 313
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 44.3 bits (103), Expect = 2e-04
Identities = 18/52 (34%), Positives = 30/52 (57%)
Query: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTY 153
P +C +C +V + L G++ GP I+ + R+N A G+ DVG KT++
Sbjct: 145 PPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSF 196
Score = 30.0 bits (66), Expect = 3.0
Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 7/45 (15%)
Query: 243 STGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPK 287
STG ++ A+ CD V YG + NY + HY+E K
Sbjct: 304 STGALMLLTALHTCDQVSAYGFITSNY-------WKFSDHYFERK 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,281,367
Number of Sequences: 37866
Number of extensions: 707506
Number of successful extensions: 2493
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2417
Number of HSP's gapped (non-prelim): 56
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.