Guide to the Human Genome
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Search of human proteins with 195972894

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195972894 hypothetical protein LOC254528 [Homo sapiens]
         (442 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195972894 hypothetical protein LOC254528 [Homo sapiens]            883   0.0  
gi|110349719 titin isoform N2-A [Homo sapiens]                         31   2.0  
gi|4506583 replication protein A1, 70kDa [Homo sapiens]                31   2.0  
gi|93102364 SWAP-70 protein [Homo sapiens]                             30   3.4  
gi|4505487 occludin [Homo sapiens]                                     30   5.7  
gi|13654239 WW domain containing E3 ubiquitin protein ligase 1 [...    30   5.7  
gi|134142348 myotubularin related protein 6 [Homo sapiens]             29   7.5  

>gi|195972894 hypothetical protein LOC254528 [Homo sapiens]
          Length = 442

 Score =  883 bits (2282), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MANSFAARIFTTLSDLQTNMANLKVIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPA 60
           MANSFAARIFTTLSDLQTNMANLKVIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPA
Sbjct: 1   MANSFAARIFTTLSDLQTNMANLKVIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPA 60

Query: 61  HFVNAASWGNEDYIKSLSDSFRVGDCVIIENPLIQRKEIEREEKFSPATPSNCKLLLSEN 120
           HFVNAASWGNEDYIKSLSDSFRVGDCVIIENPLIQRKEIEREEKFSPATPSNCKLLLSEN
Sbjct: 61  HFVNAASWGNEDYIKSLSDSFRVGDCVIIENPLIQRKEIEREEKFSPATPSNCKLLLSEN 120

Query: 121 HSTVKVCSSYEVDTKLLSLIHLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEP 180
           HSTVKVCSSYEVDTKLLSLIHLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEP
Sbjct: 121 HSTVKVCSSYEVDTKLLSLIHLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEP 180

Query: 181 KYFTTSDRRKGQRCEVRLYDETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDK 240
           KYFTTSDRRKGQRCEVRLYDETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDK
Sbjct: 181 KYFTTSDRRKGQRCEVRLYDETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDK 240

Query: 241 FRNCMTATVISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDV 300
           FRNCMTATVISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDV
Sbjct: 241 FRNCMTATVISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDV 300

Query: 301 YTVEQLKGKALKNEGKADPSYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCT 360
           YTVEQLKGKALKNEGKADPSYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCT
Sbjct: 301 YTVEQLKGKALKNEGKADPSYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCT 360

Query: 361 TCNKNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTFVLSHRARSGLKIS 420
           TCNKNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTFVLSHRARSGLKIS
Sbjct: 361 TCNKNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTFVLSHRARSGLKIS 420

Query: 421 VLSCKLADPTEASRNLSGQKHV 442
           VLSCKLADPTEASRNLSGQKHV
Sbjct: 421 VLSCKLADPTEASRNLSGQKHV 442


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 1/79 (1%)

Query: 364  KNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTFVLSHRARSGLKISVLS 423
            K  +  K+   S H+L   T   G  H C     V  +T  CT  L    R   K++ L+
Sbjct: 5562 KYKIASKNFHTSIHILNVDTSDIGEYH-CKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLT 5620

Query: 424  CKLADPTEASRNLSGQKHV 442
                +P E   ++ G + +
Sbjct: 5621 VVAGEPAELQASIEGAQPI 5639


>gi|4506583 replication protein A1, 70kDa [Homo sapiens]
          Length = 616

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 53/231 (22%), Positives = 91/231 (39%), Gaps = 35/231 (15%)

Query: 141 HLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEPKYFTT-SDRRKGQRCEVRLY 199
           HLP  +  D+  + D+    +     +++++   KS  +    T  S+ R+  +  + L 
Sbjct: 294 HLPTVQ-FDFTGIDDLE---NKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLM 349

Query: 200 DETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDKFRNCMTATVISKTIITTNP 259
           D +      T W  ++     S   R+ V+     R++    R+    +V+S + I  NP
Sbjct: 350 DTSGKVVTATLWGEDADKFDGS---RQPVLAIKGARVSDFGGRSL---SVLSSSTIIANP 403

Query: 260 DIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDVYTVEQLKGKALKNEGKADP 319
           DIPEA  L  +   + E   LD    S  K      +  +  T+ ++K + L    K D 
Sbjct: 404 DIPEAYKLRGWF--DAEGQALDGVSISDLKSGGVGGSNTNWKTLYEVKSENLGQGDKPD- 460

Query: 320 SYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCTT--CNKNSLD 368
                  Y S++        VV  R  +C Y        C T  CNK  +D
Sbjct: 461 -------YFSSV------ATVVYLRKENCMY------QACPTQDCNKKVID 492


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 8/87 (9%)

Query: 212 DNESILLAQSWMPRETVIFASDVRINFDKFR-NCMTATVISKTIITTNP------DIPEA 264
           D+E  +  Q +MP         V+ NFDK   N M  T+  K  +T NP      D  + 
Sbjct: 59  DDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKI 118

Query: 265 NILLNFIRENK-ETNVLDDEIDSYFKE 290
            ++ NF+ E+K    ++ +EI+   K+
Sbjct: 119 WVIFNFLSEDKYPLIIVSEEIEYLLKK 145


>gi|4505487 occludin [Homo sapiens]
          Length = 522

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 274 NKETNVLDDEIDSYFKESINLSTIVDVYT-VEQLKGKA 310
           NKE + LD E+D Y +ES       D Y  ++Q+KG A
Sbjct: 454 NKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSA 491


>gi|13654239 WW domain containing E3 ubiquitin protein ligase 1
           [Homo sapiens]
          Length = 922

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 9/111 (8%)

Query: 250 ISKTIITTNPDIPEANILLNFIRENK----ETNVLDDEIDSYFKESINLSTIVDVYTVE- 304
           + + ++  N  +      L    ENK    +T  L   +D    E  N++      T+E 
Sbjct: 101 LKQALLIHNRKLERVKEQLKLSLENKNGIAQTGELTVVLDGLVIEQENITNCSSSPTIEI 160

Query: 305 QLKGKALKNEGKADPSYGILYAYISTLNIDDE--TTKVVRNRCSSCGYIVN 353
           Q  G AL   G+         A   T  ID+   T+ +V+N C  C Y+VN
Sbjct: 161 QENGDALHENGEPSARTTARLAVEGTNGIDNHVPTSTLVQNSC--CSYVVN 209


>gi|134142348 myotubularin related protein 6 [Homo sapiens]
          Length = 621

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 7/107 (6%)

Query: 192 QRCEVRLYDETESSFAMTCWDNESIL--LAQSWMPRETVIFASDVRINFDKFRNCMTATV 249
           +R E++L ++T S +     D +  L  L  S   R TV+  + V  NF  +RN     +
Sbjct: 444 EREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNFKFWRN-----M 498

Query: 250 ISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLST 296
             +   T +P     NI++N   +NK+      +++S  K+  N  T
Sbjct: 499 YHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQT 545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,238,557
Number of Sequences: 37866
Number of extensions: 637581
Number of successful extensions: 1655
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1650
Number of HSP's gapped (non-prelim): 11
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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