Search of human proteins with 195947365

Search of human proteins with 195947365

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195947365 hephaestin isoform c [Homo sapiens]
         (1160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195947365 hephaestin isoform c [Homo sapiens]                     2420   0.0  
gi|195963313 hephaestin isoform a [Homo sapiens]                     2415   0.0  
gi|7662254 hephaestin isoform b [Homo sapiens]                       1846   0.0  
gi|148886707 hephaestin-like 1 [Homo sapiens]                        1208   0.0  
gi|4557485 ceruloplasmin precursor [Homo sapiens]                    1071   0.0  
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...   417   e-116
gi|105990535 coagulation factor V precursor [Homo sapiens]            397   e-110
gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]           33   2.1  
gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens]           33   2.1  
gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens]           33   2.1  
gi|226053126 paternally expressed 3 isoform 1 [Homo sapiens]           33   2.1  
gi|33354285 paternally expressed 3 isoform 1 [Homo sapiens]            33   2.1  
gi|22212918 ciliary neurotrophic factor receptor preproprotein [...    32   2.7  
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H...    32   2.7  
gi|73760405 thymopoietin isoform beta [Homo sapiens]                   32   3.5  
gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo sap...    32   4.6  
gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo sap...    31   7.8  
gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo sap...    31   7.8  

>gi|195947365 hephaestin isoform c [Homo sapiens]
          Length = 1160

 Score = 2420 bits (6271), Expect = 0.0
 Identities = 1160/1160 (100%), Positives = 1160/1160 (100%)

Query: 1    MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV 60
            MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV
Sbjct: 1    MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV 60

Query: 61   ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN 120
            ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN
Sbjct: 61   ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN 120

Query: 121  FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD 180
            FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD
Sbjct: 121  FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD 180

Query: 181  PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL 240
            PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL
Sbjct: 181  PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL 240

Query: 241  SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM 300
            SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
Sbjct: 241  SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM 300

Query: 301  GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM 360
            GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
Sbjct: 301  GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM 360

Query: 361  QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF 420
            QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
Sbjct: 361  QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF 420

Query: 421  QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS 480
            QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
Sbjct: 421  QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS 480

Query: 481  QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW 540
            QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
Sbjct: 481  QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW 540

Query: 541  MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ 600
            MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
Sbjct: 541  MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ 600

Query: 601  AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG 660
            AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
Sbjct: 601  AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG 660

Query: 661  VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ 720
            VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
Sbjct: 661  VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ 720

Query: 721  CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL 780
            CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
Sbjct: 721  CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL 780

Query: 781  GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH 840
            GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
Sbjct: 781  GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH 840

Query: 841  AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV 900
            AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
Sbjct: 841  AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV 900

Query: 901  GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET 960
            GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
Sbjct: 901  GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET 960

Query: 961  FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY 1020
            FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
Sbjct: 961  FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY 1020

Query: 1021 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK 1080
            RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
Sbjct: 1021 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK 1080

Query: 1081 ETEKVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRK 1140
            ETEKVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRK
Sbjct: 1081 ETEKVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRK 1140

Query: 1141 LRRNRRSILDDSFKLLSFKQ 1160
            LRRNRRSILDDSFKLLSFKQ
Sbjct: 1141 LRRNRRSILDDSFKLLSFKQ 1160


>gi|195963313 hephaestin isoform a [Homo sapiens]
          Length = 1161

 Score = 2415 bits (6259), Expect = 0.0
 Identities = 1160/1161 (99%), Positives = 1160/1161 (99%), Gaps = 1/1161 (0%)

Query: 1    MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV 60
            MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV
Sbjct: 1    MWAMESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIV 60

Query: 61   ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN 120
            ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN
Sbjct: 61   ASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKN 120

Query: 121  FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD 180
            FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD
Sbjct: 121  FATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDAD 180

Query: 181  PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL 240
            PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL
Sbjct: 181  PACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENL 240

Query: 241  SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM 300
            SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
Sbjct: 241  SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM 300

Query: 301  GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM 360
            GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
Sbjct: 301  GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM 360

Query: 361  QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF 420
            QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
Sbjct: 361  QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF 420

Query: 421  QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS 480
            QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
Sbjct: 421  QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS 480

Query: 481  QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW 540
            QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
Sbjct: 481  QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW 540

Query: 541  MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ 600
            MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
Sbjct: 541  MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ 600

Query: 601  AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG 660
            AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
Sbjct: 601  AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG 660

Query: 661  VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ 720
            VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
Sbjct: 661  VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ 720

Query: 721  CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL 780
            CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
Sbjct: 721  CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL 780

Query: 781  GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH 840
            GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
Sbjct: 781  GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH 840

Query: 841  AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV 900
            AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
Sbjct: 841  AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV 900

Query: 901  GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET 960
            GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
Sbjct: 901  GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET 960

Query: 961  FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY 1020
            FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
Sbjct: 961  FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY 1020

Query: 1021 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK 1080
            RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
Sbjct: 1021 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK 1080

Query: 1081 ETEK-VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR 1139
            ETEK VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
Sbjct: 1081 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR 1140

Query: 1140 KLRRNRRSILDDSFKLLSFKQ 1160
            KLRRNRRSILDDSFKLLSFKQ
Sbjct: 1141 KLRRNRRSILDDSFKLLSFKQ 1161


>gi|7662254 hephaestin isoform b [Homo sapiens]
          Length = 891

 Score = 1846 bits (4782), Expect = 0.0
 Identities = 890/891 (99%), Positives = 890/891 (99%), Gaps = 1/891 (0%)

Query: 271  MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP 330
            MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP
Sbjct: 1    MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP 60

Query: 331  ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH 390
            ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH
Sbjct: 61   ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH 120

Query: 391  EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL 450
            EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL
Sbjct: 121  EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL 180

Query: 451  EEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGL 510
            EEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGL
Sbjct: 181  EEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGL 240

Query: 511  VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGA 570
            VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGA
Sbjct: 241  VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGA 300

Query: 571  DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFL 630
            DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFL
Sbjct: 301  DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFL 360

Query: 631  FSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIM 690
            FSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIM
Sbjct: 361  FSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIM 420

Query: 691  QPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYC 750
            QPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYC
Sbjct: 421  QPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYC 480

Query: 751  PDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHL 810
            PDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHL
Sbjct: 481  PDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHL 540

Query: 811  GILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPER 870
            GILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPER
Sbjct: 541  GILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPER 600

Query: 871  SGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLI 930
            SGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLI
Sbjct: 601  SGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLI 660

Query: 931  FDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVA 990
            FDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVA
Sbjct: 661  FDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVA 720

Query: 991  WYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCH 1050
            WYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCH
Sbjct: 721  WYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCH 780

Query: 1051 VTDHVHAGMETLFTVFSRTEHLSPLTVITKETEK-VPPRDIEEGNVKMLGMQIPIKNVEM 1109
            VTDHVHAGMETLFTVFSRTEHLSPLTVITKETEK VPPRDIEEGNVKMLGMQIPIKNVEM
Sbjct: 781  VTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEM 840

Query: 1110 LASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ 1160
            LASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ
Sbjct: 841  LASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ 891



 Score =  529 bits (1362), Expect = e-150
 Identities = 287/706 (40%), Positives = 401/706 (56%), Gaps = 27/706 (3%)

Query: 23  LTDGATRVYYLGIRDVQWNYAPKGRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIY 81
           L  G  R Y++   ++QW+Y P G +  T + L +   ++  F +   +RIGGTY K  Y
Sbjct: 107 LLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRY 166

Query: 82  KEYKDDSYTDEV--AQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDS 139
           + ++D+++ +++   +   LG LGPV++AEVGD I +   N A++P+++ PHGVFYEKD 
Sbjct: 167 EAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDY 226

Query: 140 EGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIA 199
           EG++Y DGSS P        P     Y WT+P    PT  DPACLTW+Y S  D  RD  
Sbjct: 227 EGTVYNDGSSYPGLV---AKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTN 283

Query: 200 TGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVD 259
           +GL+GPL+ C+ GAL  +   +++ VD +FFLLF+V+DEN SW+ N N A    D   + 
Sbjct: 284 SGLVGPLLVCRAGALGADG--KQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLS 341

Query: 260 KEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTR 319
           ++ E FQ+SNRMHAINGF+F NLP L+MC    VAWHL G+G E DVH   F G  +  +
Sbjct: 342 EDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQ 401

Query: 320 GHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSC--SMAPPVDL 377
           G     A +FP TFV A M P   GT+ I CQ  SH   GM+A+Y V  C    A P   
Sbjct: 402 GMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQR 461

Query: 378 LTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYE 437
                R Y+I A E++WDY P         N  E  S    F       +G  Y K  + 
Sbjct: 462 YQA-ARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFR 520

Query: 438 AFQDETFQ-EKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDY 496
            + D TF+  +     + HLGILGP+I+ EVGD + VVF N AS+P+S+  HGV      
Sbjct: 521 EYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVL----- 575

Query: 497 EGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGL 556
                 + ++   L A+P E VTY+W +P  +GP   D AC++W+Y+SA DPI+D  SGL
Sbjct: 576 ------ESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGL 629

Query: 557 VGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAA-AMLDFRLLSEDIE 615
           VGPL +C+ G L   G +  +D+EF LLF + DENKSWY   N A     D   ++   E
Sbjct: 630 VGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDE 689

Query: 616 GFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQL---QG 672
            F +SN+MHAING L++NL  L M +G+ VAW++L +G + D+H + F   +      + 
Sbjct: 690 TFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGEN 749

Query: 673 MRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNV 718
            R     LFP TF +  M   N GT+ ++C    H  AGM  ++ V
Sbjct: 750 YRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTV 795


>gi|148886707 hephaestin-like 1 [Homo sapiens]
          Length = 1159

 Score = 1208 bits (3126), Expect = 0.0
 Identities = 575/1117 (51%), Positives = 766/1117 (68%), Gaps = 15/1117 (1%)

Query: 23   LTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYK 82
            L    TR YY+GI +  WNY P+G+NVIT +    D +A+ FL+   NRIG  YKK +Y+
Sbjct: 21   LVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYR 80

Query: 83   EYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGS 142
             + D +Y+ E+ +P WLGFLGP+L+AEVGDVI+IHLKNFA+RPY++HPHGVFY KDSEG+
Sbjct: 81   RFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGA 140

Query: 143  LYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGL 202
            LYPDG+SG  K DD VPPG ++ Y W + E +APT AD  CLTW+YHSH+DAP+DI +GL
Sbjct: 141  LYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGL 200

Query: 203  IGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKED 262
            IGPL+ CK G L+  S   R DVD +F ++F++VDEN SW+LNENI  +C++P SVDK+D
Sbjct: 201  IGPLLVCKEGILNRYSGT-RNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKD 259

Query: 263  ETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHH 322
              FQ SN+MHA+NG++FGN PE +MC  + V+WHLFGMGNEID+H+ +F+G    +RGH 
Sbjct: 260  AVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHR 319

Query: 323  TDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKV 382
            TDV N+FPATF+T EM+   PG W+I+CQV+ H + GM   Y V +C        + G+ 
Sbjct: 320  TDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQ 379

Query: 383  RQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDE 442
            R+YFI A +I WDY P G++  +G  L   GS SD +F +  +RIGG YWKVRY  F D 
Sbjct: 380  RRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDA 439

Query: 443  TFQEKMHLE-EDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVY 501
            TF ++  L  E+ HLGILGPVI+AEVGDT+ V F N+A + +S+ PHGV Y+K  +    
Sbjct: 440  TFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPN 499

Query: 502  NDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLL 561
             DG   PG   KP E  TY+WTVP    PTA DP CLT++YFSA DPI+DT+SGLVGPLL
Sbjct: 500  LDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLL 559

Query: 562  VCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNAN-QAAAMLDFRLLSEDIEGFQDS 620
            VC+ G L ADG QKG+DKEF+LLFTV DEN S Y + N Q      F +  ED E F  S
Sbjct: 560  VCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE-FVKS 618

Query: 621  NRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAML 680
            NRMHA+NG+++ N P L+MCK D V+WHL+GLGT+TD+HG++FQGNT+ L+G  + +  L
Sbjct: 619  NRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLAL 678

Query: 681  FPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYI 740
            FPH    A MQPD+ G F ++C    H   GM  IY VS C     +  QRY   R +YI
Sbjct: 679  FPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPS-EQRYGMIRTFYI 737

Query: 741  MAEEVEWDYCPDRSWERE-WHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRI 799
             AEEVEWDY P+++WE E  H  +  + +G IF++  +  +GS+YKK V+REYTDG F  
Sbjct: 738  AAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVE 797

Query: 800  PRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPL---AAE 856
             + R   EEHL +LGP+I  EVG+ + ++FKN ASRPYS+ A GV E  +         +
Sbjct: 798  IKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTK 857

Query: 857  PGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGG 916
            PGEV TY+WNIP+RSGPGP+D  C+ W+YYS V+ +KD YSGL+GPL  C+KG+L   G 
Sbjct: 858  PGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGR 917

Query: 917  RSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYA 976
            RSD+D EFALLFL+F+EN+SWYL++N+  + ++DP      D+ F ESN+MHAINGK++ 
Sbjct: 918  RSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD-FEESNRMHAINGKIFG 976

Query: 977  NLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVE 1036
            NL GL M +     WY+L +G +VD+HTIH+HAESFL++  ++YR DV DLFPGTF+ +E
Sbjct: 977  NLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIE 1036

Query: 1037 MVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKVP---PRDIEEG 1093
            + A +PGTWL+HCHV+DH+HAGMET +TV    ++  P +  +      P   P +   G
Sbjct: 1037 LFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSPGVASHPATVPSNERPG 1096

Query: 1094 NVKM--LGMQIPIKNVEMLASVLVAISVTLLLVVLAL 1128
              ++   G  +     +    +L  I + LL+  + L
Sbjct: 1097 KEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVIL 1133


>gi|4557485 ceruloplasmin precursor [Homo sapiens]
          Length = 1065

 Score = 1071 bits (2769), Expect = 0.0
 Identities = 517/1052 (49%), Positives = 702/1052 (66%), Gaps = 26/1052 (2%)

Query: 31   YYLGIRDVQWNYAPKG--RNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDS 88
            YY+GI +  W+YA     + +I+     S+I    +L++  +RIG  YKK +Y +Y D++
Sbjct: 24   YYIGIIETTWDYASDHGEKKLISVDTEHSNI----YLQNGPDRIGRLYKKALYLQYTDET 79

Query: 89   YTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGS 148
            +   + +P WLGFLGP+++AE GD + +HLKN A+RPYT H HG+ Y K+ EG++YPD +
Sbjct: 80   FRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNT 139

Query: 149  SGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLIT 208
            +   +ADD V PG  + Y     E  +P + D  C+T IYHSH+DAP+DIA+GLIGPLI 
Sbjct: 140  TDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLII 199

Query: 209  CKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQES 268
            CK+ +LD     + + +D +F ++FSVVDEN SW+L +NI TYCS+P  VDK++E FQES
Sbjct: 200  CKKDSLDKE---KEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQES 256

Query: 269  NRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANI 328
            NRM+++NG+ FG+LP L+MCA+ RV W+LFGMGNE+DVH AFFHGQ LT + +  D  N+
Sbjct: 257  NRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINL 316

Query: 329  FPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGK-VRQYFI 387
            FPAT   A MV   PG W++SCQ  +H + G+QA ++V+ C+ +   D + GK VR Y+I
Sbjct: 317  FPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKHVRHYYI 376

Query: 388  EAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETF-QE 446
             A EI W+Y P G D  T +NL  PGS S  FF++ ++RIGG+Y K+ Y  + D +F   
Sbjct: 377  AAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNR 436

Query: 447  KMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYN---- 502
            K    E+ HLGILGPVI AEVGDTI+V F+N+ + P S++P GV + K+ EGT Y+    
Sbjct: 437  KERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYN 496

Query: 503  -DGSSYPGLVA--KPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGP 559
                S P   +   P E  TY WTVP   GPT  DP CL  MY+SA DP +D  +GL+GP
Sbjct: 497  PQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGP 556

Query: 560  LLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQD 619
            + +C+ G+L A+G+QK VDKEF+L  TV DEN+S     N          + ++ E FQ+
Sbjct: 557  MKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQE 616

Query: 620  SNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAM 679
            SN+MH++NGF++ N P L MCKGD+V W+L   G E DVHG+ F GNT   +G R+  A 
Sbjct: 617  SNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTAN 676

Query: 680  LFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYY 739
            LFP T +   M PD  GTF + C    H   GM+  Y V+QC   Q+     Y   R YY
Sbjct: 677  LFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQC-RRQSEDSTFYLGERTYY 735

Query: 740  IMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRI 799
            I A EVEWDY P R WE+E H+  E+ +    FL   +  +GS+YKK V+R+YTD TFR+
Sbjct: 736  IAAVEVEWDYSPQREWEKELHHLQEQ-NVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRV 794

Query: 800  PRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGV-LESTTVWPLAAEPG 858
            P  R   EEHLGILGP +  +VGD + ++FKN A+RPYS+HAHGV  ES+TV P    PG
Sbjct: 795  PVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVTPTL--PG 852

Query: 859  EVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRS 918
            E +TY W IPERSG G  DSAC+ W YYS VD +KD+YSGL+GPL +C++  L+    R 
Sbjct: 853  ETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFNPRR 912

Query: 919  DMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANL 978
             +  EFALLFL+FDEN+SWYL++N+ T+ S  P  +N  DE F+ESNKMHAING+++ NL
Sbjct: 913  KL--EFALLFLVFDENESWYLDDNIKTY-SDHPEKVNKDDEEFIESNKMHAINGRMFGNL 969

Query: 979  RGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMV 1038
            +GLTM+ G+ V WY++ MG ++DLHT+HFH  SF Y++   Y +DV D+FPGT++ +EM 
Sbjct: 970  QGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMF 1029

Query: 1039 ASNPGTWLMHCHVTDHVHAGMETLFTVFSRTE 1070
               PG WL+HCHVTDH+HAGMET +TV    +
Sbjct: 1030 PRTPGIWLLHCHVTDHIHAGMETTYTVLQNED 1061



 Score =  500 bits (1287), Expect = e-141
 Identities = 279/707 (39%), Positives = 393/707 (55%), Gaps = 35/707 (4%)

Query: 29   RVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASS-FLKSDKNRIGGTYKKTIYKEYKDD 87
            R YY+   ++ WNYAP G ++ T + L +    S+ F +    RIGG+YKK +Y+EY D 
Sbjct: 372  RHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDA 431

Query: 88   SYT---DEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLY 144
            S+T   +   +   LG LGPV+ AEVGD I +   N    P +I P GV + K++EG+ Y
Sbjct: 432  SFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYY 491

Query: 145  PDGSSGPLKADDSVPPGGSHI-------YNWTIPEGHAPTDADPACLTWIYHSHVDAPRD 197
                +   +   SVPP  SH+       Y WT+P+   PT+ADP CL  +Y+S VD  +D
Sbjct: 492  SPNYNPQSR---SVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKD 548

Query: 198  IATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPAS 257
            I TGLIGP+  CK+G+L  N   +++DVD +F+L  +V DEN S  L +NI  + + P  
Sbjct: 549  IFTGLIGPMKICKKGSLHANG--RQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQ 606

Query: 258  VDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLT 317
            VDKEDE FQESN+MH++NGF++GN P L MC    V W+LF  GNE DVH  +F G    
Sbjct: 607  VDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYL 666

Query: 318  TRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDL 377
             RG   D AN+FP T +T  M P   GT+ + C    H+  GM+  Y V  C        
Sbjct: 667  WRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDST 726

Query: 378  LTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYE 437
                 R Y+I A E++WDY P         +L+E  ++S+ F  K    IG  Y KV Y 
Sbjct: 727  FYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQ-NVSNAFLDKGEFYIGSKYKKVVYR 785

Query: 438  AFQDETFQEKMHLE-EDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDY 496
             + D TF+  +  + E+ HLGILGP + A+VGD ++++F N A++P+S+  HGV  E   
Sbjct: 786  QYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTE--- 842

Query: 497  EGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGL 556
                    +  P L   P E +TY W +P  +G   +D AC+ W Y+S  D ++D  SGL
Sbjct: 843  ------SSTVTPTL---PGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGL 893

Query: 557  VGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEG 616
            +GPL+VCR   L     ++ +  EF LLF V DEN+SWY + N          +++D E 
Sbjct: 894  IGPLIVCRRPYLKVFNPRRKL--EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEE 951

Query: 617  FQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQL--QGMR 674
            F +SN+MHAING +F NL  L M  GD V W+L+G+G E D+H V F G++ Q   +G+ 
Sbjct: 952  FIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVY 1011

Query: 675  KGAAM-LFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ 720
                  +FP T+    M P   G + ++C    H  AGM   Y V Q
Sbjct: 1012 SSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQ 1058


>gi|4503647 coagulation factor VIII isoform a precursor [Homo
           sapiens]
          Length = 2351

 Score =  417 bits (1071), Expect = e-116
 Identities = 251/735 (34%), Positives = 370/735 (50%), Gaps = 64/735 (8%)

Query: 27  ATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKD 86
           ATR YYLG  ++ W+Y    ++ +   P+D+        KS        YKKT++ E+ D
Sbjct: 20  ATRRYYLGAVELSWDYM---QSDLGELPVDARF-PPRVPKSFPFNTSVVYKKTLFVEFTD 75

Query: 87  DSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPD 146
             +     +P W+G LGP +QAEV D ++I LKN A+ P ++H  GV Y K SEG+ Y D
Sbjct: 76  HLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDD 135

Query: 147 GSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPL 206
            +S   K DD V PGGSH Y W + + + P  +DP CLT+ Y SHVD  +D+ +GLIG L
Sbjct: 136 QTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGAL 195

Query: 207 ITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQ 266
           + C+ G+L      ++    H F LLF+V DE  SWH      +   +    D++  + +
Sbjct: 196 LVCREGSL----AKEKTQTLHKFILLFAVFDEGKSWH------SETKNSLMQDRDAASAR 245

Query: 267 ESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVA 326
              +MH +NG+V  +LP L  C +K V WH+ GMG   +VH+ F  G     R H     
Sbjct: 246 AWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASL 305

Query: 327 NIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPV----------- 375
            I P TF+TA+ +  + G +L+ C ++SH  DGM+A  KV SC   P +           
Sbjct: 306 EISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDY 365

Query: 376 -DLLTG---------------------------KVRQYFIEAHEIQWDYGPMGHDGSTGK 407
            D LT                            K   ++I A E  WDY P+        
Sbjct: 366 DDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPL-------V 418

Query: 408 NLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEV 467
              +  S   ++      RIG  Y KVR+ A+ DETF+ +  ++ +   GILGP++  EV
Sbjct: 419 LAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHES--GILGPLLYGEV 476

Query: 468 GDTIQVVFYNRASQPFSMQPHGVFYEKD-YEGTVYNDGSSYPGLVAKPFEKVTYRWTVPP 526
           GDT+ ++F N+AS+P+++ PHG+   +  Y   +             P E   Y+WTV  
Sbjct: 477 GDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTV 536

Query: 527 HAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFT 586
             GPT  DP CLT  Y S  +  RD  SGL+GPLL+C   ++   G Q   DK   +LF+
Sbjct: 537 EDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFS 596

Query: 587 VLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVA 646
           V DEN+SWY   N    + +   +  +   FQ SN MH+ING++F +L +L +C  +   
Sbjct: 597 VFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSL-QLSVCLHEVAY 655

Query: 647 WHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGS 706
           W++L +G +TD   V F G T + + + +    LFP +     M  +N G + + C    
Sbjct: 656 WYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSD 715

Query: 707 HREAGMRAIYNVSQC 721
            R  GM A+  VS C
Sbjct: 716 FRNRGMTALLKVSSC 730



 Score =  387 bits (994), Expect = e-107
 Identities = 250/751 (33%), Positives = 366/751 (48%), Gaps = 109/751 (14%)

Query: 383  RQYFIEAHEIQWDYGPMGHD-GSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQD 441
            R+Y++ A E+ WDY  M  D G    + R P  +   F   +S      Y K  +  F D
Sbjct: 22   RRYYLGAVELSWDY--MQSDLGELPVDARFPPRVPKSFPFNTSV----VYKKTLFVEFTD 75

Query: 442  ETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVY 501
              F   +       +G+LGP I+AEV DT+ +   N AS P S+   GV Y K  EG  Y
Sbjct: 76   HLFN--IAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEY 133

Query: 502  NDGSSYPGLVAKPFEKV------TYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSG 555
            +D +S      K  +KV      TY W V    GP A DP CLT+ Y S  D ++D NSG
Sbjct: 134  DDQTSQR---EKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSG 190

Query: 556  LVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIE 615
            L+G LLVCR G+L  +  Q     +F LLF V DE KSW+S    +       +   D  
Sbjct: 191  LIGALLVCREGSLAKEKTQ--TLHKFILLFAVFDEGKSWHSETKNSL------MQDRDAA 242

Query: 616  GFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRK 675
              +   +MH +NG++  +LP L  C   +V WH++G+GT  +VH +  +G+T  ++  R+
Sbjct: 243  SARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQ 302

Query: 676  GAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAA 735
             +  + P TF+ A     +LG F ++C   SH+  GM A   V  CP       +  + A
Sbjct: 303  ASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEA 362

Query: 736  R--------------------------------------IYYIMAEEVEWDYCP------ 751
                                                   ++YI AEE +WDY P      
Sbjct: 363  EDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPD 422

Query: 752  DRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHLG 811
            DRS++ +             +L+N    +G +YKK  F  YTD TF   + R   +   G
Sbjct: 423  DRSYKSQ-------------YLNNGPQRIGRKYKKVRFMAYTDETF---KTREAIQHESG 466

Query: 812  ILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAE--------------- 856
            ILGPL+ GEVGD L ++FKN ASRPY+++ HG+   T V PL +                
Sbjct: 467  ILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGI---TDVRPLYSRRLPKGVKHLKDFPIL 523

Query: 857  PGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGG 916
            PGE+  Y+W +    GP  +D  C++  Y S V+  +D+ SGL+GPL IC K  ++  G 
Sbjct: 524  PGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGN 583

Query: 917  RSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYA 976
            +   D+   +LF +FDEN+SWYL EN+      +P  + L+D  F  SN MH+ING ++ 
Sbjct: 584  QIMSDKRNVILFSVFDENRSWYLTENIQRF-LPNPAGVQLEDPEFQASNIMHSINGYVFD 642

Query: 977  NLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVE 1036
            +L+ L++   E   WY+L++G   D  ++ F   +F ++       D + LFP + E V 
Sbjct: 643  SLQ-LSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHK---MVYEDTLTLFPFSGETVF 698

Query: 1037 MVASNPGTWLMHCHVTDHVHAGMETLFTVFS 1067
            M   NPG W++ CH +D  + GM  L  V S
Sbjct: 699  MSMENPGLWILGCHNSDFRNRGMTALLKVSS 729



 Score =  254 bits (650), Expect = 3e-67
 Identities = 137/347 (39%), Positives = 193/347 (55%), Gaps = 21/347 (6%)

Query: 727  TPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKK 786
            +PR   +  R Y+I A E  WDY    S      N+++  S               ++KK
Sbjct: 1706 SPRSFQKKTRHYFIAAVERLWDYGMSSS-PHVLRNRAQSGSV-------------PQFKK 1751

Query: 787  AVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLE 846
             VF+E+TDG+F  P  R    EHLG+LGP I+ EV D + V F+N ASRPYS ++  +  
Sbjct: 1752 VVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISY 1811

Query: 847  STTVWPLA------AEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV 900
                   A       +P E  TY W +     P  ++  C +W Y+S VD  KD++SGL+
Sbjct: 1812 EEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLI 1871

Query: 901  GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET 960
            GPL +C    L P  GR    +EFAL F IFDE KSWY  EN+  +  + P +I ++D T
Sbjct: 1872 GPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERN-CRAPCNIQMEDPT 1930

Query: 961  FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY 1020
            F E+ + HAING +   L GL M Q +R+ WY+L+MG + ++H+IHF    F  R  E Y
Sbjct: 1931 FKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEY 1990

Query: 1021 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFS 1067
            +  + +L+PG FE VEM+ S  G W + C + +H+HAGM TLF V+S
Sbjct: 1991 KMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYS 2037



 Score =  206 bits (525), Expect = 8e-53
 Identities = 115/375 (30%), Positives = 180/375 (48%), Gaps = 29/375 (7%)

Query: 21   PQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTI 80
            P+     TR Y++   +  W+Y       +      S  V               +KK +
Sbjct: 1707 PRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSGSVPQ-------------FKKVV 1753

Query: 81   YKEYKDDSYTDEVAQPAW---LGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEK 137
            ++E+ D S+T  + +      LG LGP ++AEV D I++  +N A+RPY+ +   + YE+
Sbjct: 1754 FQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEE 1813

Query: 138  DSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRD 197
            D      P          + V P  +  Y W +    APT  +  C  W Y S VD  +D
Sbjct: 1814 DQRQGAEP--------RKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKD 1865

Query: 198  IATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPAS 257
            + +GLIGPL+ C    L  N    RQ    +F L F++ DE  SW+  EN+   C  P +
Sbjct: 1866 VHSGLIGPLLVCHTNTL--NPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCN 1923

Query: 258  VDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLT 317
            +  ED TF+E+ R HAING++   LP L M   +R+ W+L  MG+  ++H+  F G + T
Sbjct: 1924 IQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFT 1983

Query: 318  TR---GHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPP 374
             R    +   + N++P  F T EM+P + G W + C +  H   GM  L+ V S     P
Sbjct: 1984 VRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTP 2043

Query: 375  VDLLTGKVRQYFIEA 389
            + + +G +R + I A
Sbjct: 2044 LGMASGHIRDFQITA 2058



 Score =  195 bits (496), Expect = 2e-49
 Identities = 123/343 (35%), Positives = 171/343 (49%), Gaps = 25/343 (7%)

Query: 381  KVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQ 440
            K R YFI A E  WDYG M       +N  + GS+               + KV ++ F 
Sbjct: 1713 KTRHYFIAAVERLWDYG-MSSSPHVLRNRAQSGSVPQ-------------FKKVVFQEFT 1758

Query: 441  DETFQEKMHLEE-DRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGT 499
            D +F + ++  E + HLG+LGP IRAEV D I V F N+AS+P+S     + YE+D    
Sbjct: 1759 DGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQR-- 1816

Query: 500  VYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGP 559
                G+       KP E  TY W V  H  PT  +  C  W YFS  D  +D +SGL+GP
Sbjct: 1817 ---QGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGP 1873

Query: 560  LLVCRAGALG-ADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQ 618
            LLVC    L  A G+Q  V +EF L FT+ DE KSWY   N          +  +   F+
Sbjct: 1874 LLVCHTNTLNPAHGRQVTV-QEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFK 1932

Query: 619  DSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGN--TVQLQGMRKG 676
            ++ R HAING++   LP L M +   + W+LL +G+  ++H + F G+  TV+ +   K 
Sbjct: 1933 ENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKM 1992

Query: 677  AAM-LFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNV 718
            A   L+P  F    M P   G + + C  G H  AGM  ++ V
Sbjct: 1993 ALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLV 2035



 Score =  166 bits (421), Expect = 9e-41
 Identities = 114/357 (31%), Positives = 172/357 (48%), Gaps = 42/357 (11%)

Query: 732  YQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFRE 791
            + A R YY+ A E+ WDY      E     +         F  N   +    YKK +F E
Sbjct: 18   FSATRRYYLGAVELSWDYMQSDLGELPVDARFPP-RVPKSFPFNTSVV----YKKTLFVE 72

Query: 792  YTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVW 851
            +TD  F I +PR      +G+LGP I+ EV D + +  KN AS P S+HA GV    + W
Sbjct: 73   FTDHLFNIAKPRP---PWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGV----SYW 125

Query: 852  PLA--AE----------------PGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIK 893
              +  AE                PG   TY W + + +GP  +D  C+++ Y S VD +K
Sbjct: 126  KASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVK 185

Query: 894  DMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGS 953
            D+ SGL+G L +C++G L     ++    +F LLF +FDE KSW+ E   +    +D  S
Sbjct: 186  DLNSGLIGALLVCREGSLAKE--KTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAAS 243

Query: 954  INLQDETFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFL 1013
                        KMH +NG +  +L GL     + V W+++ MG   ++H+I     +FL
Sbjct: 244  ARAWP-------KMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFL 296

Query: 1014 YRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTE 1070
             RN   +R   +++ P TF   + +  + G +L+ CH++ H H GME    V S  E
Sbjct: 297  VRN---HRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPE 350


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score =  397 bits (1021), Expect = e-110
 Identities = 241/731 (32%), Positives = 360/731 (49%), Gaps = 73/731 (9%)

Query: 10  LWALLFMQSLW----PQLTDGAT-RVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSF 64
           LW L+ + + W     Q T+ A  R +Y+  + + W+Y P+  N   N  + S       
Sbjct: 8   LWVLVVLGTSWVGWGSQGTEAAQLRQFYVAAQGISWSYRPEPTNSSLNLSVTS------- 60

Query: 65  LKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATR 124
                      +KK +Y+EY +  +  E  Q    G LGP L AEVGD+I +H KN A +
Sbjct: 61  -----------FKKIVYREY-EPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADK 108

Query: 125 PYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACL 184
           P +IHP G+ Y K SEG+ Y D +    K DD+V PG  + Y W+I E   PT  DP CL
Sbjct: 109 PLSIHPQGIRYSKLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCL 168

Query: 185 TWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHL 244
           T IY+SH +   D  +GLIGPL+ CK+G L       ++  D    LLF+V DE+ SW  
Sbjct: 169 THIYYSHENLIEDFNSGLIGPLLICKKGTLTEGG--TQKTFDKQIVLLFAVFDESKSWS- 225

Query: 245 NENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEI 304
                                Q S+ M+ +NG+V G +P++ +CA   ++WHL GM +  
Sbjct: 226 ---------------------QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGP 264

Query: 305 DVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALY 364
           ++ +  F+GQ+L    H      +  AT  TA M     G W+IS     H + GMQA  
Sbjct: 265 ELFSIHFNGQVLEQNHHKVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYI 324

Query: 365 KVKSC-SMAPPVDLLTGKVR------QYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISD 417
            +K+C      +  +T + R      +YFI A E+ WDY P+            P ++  
Sbjct: 325 DIKNCPKKTRNLKKITREQRRHMKRWEYFIAAEEVIWDYAPV-----------IPANMDK 373

Query: 418 KF----FQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQV 473
           K+        S++IG  Y KV Y  ++DE+F +       +  GILGP+IRA+V DT+++
Sbjct: 374 KYRSQHLDNFSNQIGKHYKKVMYTQYEDESFTKHTVNPNMKEDGILGPIIRAQVRDTLKI 433

Query: 474 VFYNRASQPFSMQPHGVF---YEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGP 530
           VF N AS+P+S+ PHGV    YE +   +  +  ++      +P E  TY+W +     P
Sbjct: 434 VFKNMASRPYSIYPHGVTFSPYEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEP 493

Query: 531 TAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDE 590
           T  D  CLT  Y+S  D +RD  SGL+G LL+C++ +L   G Q+  D E   +F V DE
Sbjct: 494 TENDAQCLTRPYYSDVDIMRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDE 553

Query: 591 NKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLL 650
           NKSWY   N      +   +  D   F +SN M  ING++  ++  L  C  DTV WH  
Sbjct: 554 NKSWYLEDNINKFCENPDEVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFC 613

Query: 651 GLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREA 710
            +GT+ ++  + F G++       +    LFP       +  DN+GT+ +     S R  
Sbjct: 614 SVGTQNEILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSK 673

Query: 711 GMRAIYNVSQC 721
            +R  +   +C
Sbjct: 674 KLRLKFRDVKC 684



 Score =  367 bits (943), Expect = e-101
 Identities = 230/693 (33%), Positives = 344/693 (49%), Gaps = 85/693 (12%)

Query: 381  KVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQ 440
            ++RQ+++ A  I W Y P   + S   ++                    ++ K+ Y  ++
Sbjct: 30   QLRQFYVAAQGISWSYRPEPTNSSLNLSVT-------------------SFKKIVYREYE 70

Query: 441  DETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTV 500
                +EK    +    G+LGP + AEVGD I+V F N+A +P S+ P G+ Y K  EG  
Sbjct: 71   PYFKKEK---PQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGAS 127

Query: 501  YNDGSSYPGL----VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGL 556
            Y D  ++P         P  + TY W++   +GPT  DP CLT +Y+S  + I D NSGL
Sbjct: 128  YLD-HTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGL 186

Query: 557  VGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEG 616
            +GPLL+C+ G L   G QK  DK+  LLF V DE+KSW                      
Sbjct: 187  IGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWS--------------------- 225

Query: 617  FQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKG 676
             Q S+ M+ +NG++   +P + +C  D ++WHLLG+ +  ++  + F G  ++    +  
Sbjct: 226  -QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKVS 284

Query: 677  AAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGH-----QATPRQR 731
            A  L   T   A M     G + I      H +AGM+A  ++  CP       + T  QR
Sbjct: 285  AITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITREQR 344

Query: 732  YQAARI-YYIMAEEVEWDYCP--DRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAV 788
                R  Y+I AEEV WDY P    + ++++ +Q          L N    +G  YKK +
Sbjct: 345  RHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQH---------LDNFSNQIGKHYKKVM 395

Query: 789  FREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLES- 847
            + +Y D +F         +E  GILGP+I+ +V D L +VFKN ASRPYS++ HGV  S 
Sbjct: 396  YTQYEDESFTKHTVNPNMKED-GILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSP 454

Query: 848  -------------TTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKD 894
                               A +PGE  TY+WNI E   P  ND+ C++  YYS VD ++D
Sbjct: 455  YEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRD 514

Query: 895  MYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSI 954
            + SGL+G L IC+   L+  G +   D E   +F +FDENKSWYLE+N+     ++P  +
Sbjct: 515  IASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNI-NKFCENPDEV 573

Query: 955  NLQDETFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLY 1014
               D  F ESN M  ING +  ++  L     + V W+  ++G   ++ TIHF   SF+Y
Sbjct: 574  KRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHSFIY 633

Query: 1015 RNGENYRADVVDLFPGTFEVVEMVASNPGTWLM 1047
              G+ +  D + LFP   E V +   N GTW++
Sbjct: 634  --GKRHE-DTLTLFPMRGESVTVTMDNVGTWML 663



 Score =  257 bits (657), Expect = 4e-68
 Identities = 144/347 (41%), Positives = 193/347 (55%), Gaps = 35/347 (10%)

Query: 736  RIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDG 795
            R YYI AEE+ WDY      E +  +  +                 + YKK VFR+Y D 
Sbjct: 1580 RNYYIAAEEISWDYSEFVQRETDIEDSDDIPE-------------DTTYKKVVFRKYLDS 1626

Query: 796  TFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVL---------- 845
            TF    PR   EEHLGILGP+I+ EV D++ V FKN ASRPYS+HAHG+           
Sbjct: 1627 TFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTY 1686

Query: 846  -ESTTVW---PLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVG 901
             + +  W     A +P    TY W+  ERSGP    SAC +W YYSAV+P KD++SGL+G
Sbjct: 1687 EDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIG 1746

Query: 902  PLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETF 961
            PL ICQKGIL          REF LLF+ FDE KSWY E+       +   S  L     
Sbjct: 1747 PLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEK-------KSRSSWRLTSSEM 1799

Query: 962  LESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYR 1021
             +S++ HAING +Y +L GL MY+ E V  ++L +G   D+H +HFH ++ L    + ++
Sbjct: 1800 KKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQHQ 1858

Query: 1022 ADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSR 1068
              V  L PG+F+ +EM AS PG WL++  V ++  AGM+T F +  R
Sbjct: 1859 LGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDR 1905



 Score =  220 bits (561), Expect = 5e-57
 Identities = 130/375 (34%), Positives = 192/375 (51%), Gaps = 31/375 (8%)

Query: 25   DGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEY 84
            +G  R YY+   ++ W+Y+   +        ++DI  S  +  D      TYKK ++++Y
Sbjct: 1576 NGNRRNYYIAAEEISWDYSEFVQR-------ETDIEDSDDIPEDT-----TYKKVVFRKY 1623

Query: 85   KDDSYTDEVAQPAW---LGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEG 141
             D ++T    +  +   LG LGP+++AEV DVI +  KN A+RPY++H HG+ YEK SEG
Sbjct: 1624 LDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEG 1683

Query: 142  SLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATG 201
              Y D S    K D++V P  S+ Y W   E   P     AC  W Y+S V+  +DI +G
Sbjct: 1684 KTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSG 1743

Query: 202  LIGPLITCKRGAL--DGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVD 259
            LIGPL+ C++G L  D N P   +    +F LLF   DE  SW+  +         +S  
Sbjct: 1744 LIGPLLICQKGILHKDSNMPMDMR----EFVLLFMTFDEKKSWYYEK------KSRSSWR 1793

Query: 260  KEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTR 319
                  ++S+  HAING ++ +LP L M  Q+ V  HL  +G   D+H   FHGQ L   
Sbjct: 1794 LTSSEMKKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLEN 1852

Query: 320  G---HHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVD 376
            G   H   V  + P +F T EM   +PG WL++ +V  + R GMQ  + +       P+ 
Sbjct: 1853 GNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMG 1912

Query: 377  LLTGKVRQYFIEAHE 391
            L TG +    I+A E
Sbjct: 1913 LSTGIISDSQIKASE 1927



 Score =  197 bits (500), Expect = 6e-50
 Identities = 124/341 (36%), Positives = 173/341 (50%), Gaps = 27/341 (7%)

Query: 380  GKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAF 439
            G  R Y+I A EI WDY            ++    I D       +    TY KV +  +
Sbjct: 1577 GNRRNYYIAAEEISWDYSEF---------VQRETDIEDSDDIPEDT----TYKKVVFRKY 1623

Query: 440  QDETFQEK-MHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEG 498
             D TF ++    E + HLGILGP+IRAEV D IQV F N AS+P+S+  HG+ YEK  EG
Sbjct: 1624 LDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEG 1683

Query: 499  TVYNDGSSY---PGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSG 555
              Y D S          +P    TY W     +GP +   AC  W Y+SA +P +D +SG
Sbjct: 1684 KTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSG 1743

Query: 556  LVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIE 615
            L+GPLL+C+ G L  D       +EF LLF   DE KSWY      ++   +RL S ++ 
Sbjct: 1744 LIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEKKSRSS---WRLTSSEM- 1799

Query: 616  GFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRK 675
              + S+  HAING ++S LP L M + + V  HLL +G   D+H V F G T+   G ++
Sbjct: 1800 --KKSHEFHAINGMIYS-LPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQ 1856

Query: 676  ---GAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMR 713
               G   L P +F    M+    G + +  + G ++ AGM+
Sbjct: 1857 HQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQ 1897



 Score =  161 bits (408), Expect = 3e-39
 Identities = 105/363 (28%), Positives = 172/363 (47%), Gaps = 63/363 (17%)

Query: 736  RIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDG 795
            R +Y+ A+ + W Y P+ +                   ++   L  + +KK V+REY + 
Sbjct: 32   RQFYVAAQGISWSYRPEPT-------------------NSSLNLSVTSFKKIVYREY-EP 71

Query: 796  TFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTT------ 849
             F+  +P++      G+LGP +  EVGDI+ V FKN A +P S+H  G+  S        
Sbjct: 72   YFKKEKPQSTIS---GLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGASY 128

Query: 850  ---VWPL-----AAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVG 901
                +P      A  PG   TY+W+I E SGP  +D  C++ IYYS  + I+D  SGL+G
Sbjct: 129  LDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGLIG 188

Query: 902  PLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETF 961
            PL IC+KG L   G +   D++  LLF +FDE+KSW          SQ            
Sbjct: 189  PLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSW----------SQS----------- 227

Query: 962  LESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYR 1021
              S+ M+ +NG +   +  +T+   + ++W++L M    +L +IHF+ +  L +N  +++
Sbjct: 228  --SSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQ-VLEQN--HHK 282

Query: 1022 ADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKE 1081
               + L   T     M     G W++      H+ AGM+    + +  +    L  IT+E
Sbjct: 283  VSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITRE 342

Query: 1082 TEK 1084
              +
Sbjct: 343  QRR 345


>gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]
          Length = 1464

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 127 TIHPHGVFYEKDSEGSLYPDGS--SGPLKADDSVPPGGSHIYNWTIPEGHAPTD 178
           T  P G+ YE    G  +   S  +   K  D   P GS  Y W++    APTD
Sbjct: 837 TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTD 890


>gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens]
          Length = 1588

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 127  TIHPHGVFYEKDSEGSLYPDGS--SGPLKADDSVPPGGSHIYNWTIPEGHAPTD 178
            T  P G+ YE    G  +   S  +   K  D   P GS  Y W++    APTD
Sbjct: 961  TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTD 1014


>gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens]
          Length = 1462

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 127 TIHPHGVFYEKDSEGSLYPDGS--SGPLKADDSVPPGGSHIYNWTIPEGHAPTD 178
           T  P G+ YE    G  +   S  +   K  D   P GS  Y W++    APTD
Sbjct: 835 TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTD 888


>gi|226053126 paternally expressed 3 isoform 1 [Homo sapiens]
          Length = 1588

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 127  TIHPHGVFYEKDSEGSLYPDGS--SGPLKADDSVPPGGSHIYNWTIPEGHAPTD 178
            T  P G+ YE    G  +   S  +   K  D   P GS  Y W++    APTD
Sbjct: 961  TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTD 1014


>gi|33354285 paternally expressed 3 isoform 1 [Homo sapiens]
          Length = 1588

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 127  TIHPHGVFYEKDSEGSLYPDGS--SGPLKADDSVPPGGSHIYNWTIPEGHAPTD 178
            T  P G+ YE    G  +   S  +   K  D   P GS  Y W++    APTD
Sbjct: 961  TFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTD 1014


>gi|22212918 ciliary neurotrophic factor receptor preproprotein
           [Homo sapiens]
          Length = 372

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 10/85 (11%)

Query: 497 EGTVYNDGSSYPG------LVAKPFEKVTYR-WTVPPHAGPTAQDPACLTWMYFSAADPI 549
           +GT +    +Y G      + AK  E  T+  W+V  HA P  ++P  LT     AA+  
Sbjct: 261 DGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLT-TEAQAAETT 319

Query: 550 RDTNSGLVGP--LLVCRAGALGADG 572
             T S L  P    +C  G LG+ G
Sbjct: 320 TSTTSSLAPPPTTKICDPGELGSGG 344


>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
           sapiens]
          Length = 372

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 10/85 (11%)

Query: 497 EGTVYNDGSSYPG------LVAKPFEKVTYR-WTVPPHAGPTAQDPACLTWMYFSAADPI 549
           +GT +    +Y G      + AK  E  T+  W+V  HA P  ++P  LT     AA+  
Sbjct: 261 DGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLT-TEAQAAETT 319

Query: 550 RDTNSGLVGP--LLVCRAGALGADG 572
             T S L  P    +C  G LG+ G
Sbjct: 320 TSTTSSLAPPPTTKICDPGELGSGG 344


>gi|73760405 thymopoietin isoform beta [Homo sapiens]
          Length = 454

 Score = 32.0 bits (71), Expect = 3.5
 Identities = 18/49 (36%), Positives = 25/49 (51%)

Query: 786 KAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNAS 834
           +A+ RE T G+ R PR R    EH  I GP+I        T++  +N S
Sbjct: 244 QALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNES 292


>gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 31.6 bits (70), Expect = 4.6
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 15/99 (15%)

Query: 825 LTVVFKNNASRPYSVHAHGVLESTTV---WPLAAEPGEVVTYQWNIPERSGPGPNDSACV 881
           LT+ +        +VH     E+ T+   WP    P ++   QW  P+  GPGP   + V
Sbjct: 380 LTIYYPPEGQPSCAVHPSS--EAVTLLCAWPGGLPPAQL---QWEGPQ--GPGPTAPSNV 432

Query: 882 SWIYYSAVDPIKDMYS-----GLVGPLAICQKGILEPHG 915
           +W + +A  P   +++       + P A+C   + EP G
Sbjct: 433 TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLG 471


>gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 30.8 bits (68), Expect = 7.8
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 10/70 (14%)

Query: 851 WPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYS-----GLVGPLAI 905
           WP    P ++   QW  P+  GPGP   + V+W + +A  P   +++       + P A+
Sbjct: 407 WPGGLPPAQL---QWEGPQ--GPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPAL 461

Query: 906 CQKGILEPHG 915
           C   + EP G
Sbjct: 462 CTVMLWEPLG 471


>gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo
           sapiens]
          Length = 859

 Score = 30.8 bits (68), Expect = 7.8
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 10/70 (14%)

Query: 851 WPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYS-----GLVGPLAI 905
           WP    P ++   QW  P+  GPGP   + V+W + +A  P   +++       + P A+
Sbjct: 407 WPGGLPPAQL---QWEGPQ--GPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPAL 461

Query: 906 CQKGILEPHG 915
           C   + EP G
Sbjct: 462 CTVMLWEPLG 471


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,224,810
Number of Sequences: 37866
Number of extensions: 2383023
Number of successful extensions: 4494
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4216
Number of HSP's gapped (non-prelim): 35
length of query: 1160
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1047
effective length of database: 13,968,660
effective search space: 14625187020
effective search space used: 14625187020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.