Guide to the Human Genome
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Search of human proteins with 194440732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
sapiens]
         (174 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi...   351   2e-97
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]   331   2e-91
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]   220   6e-58
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          32   0.21 
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]           32   0.36 
gi|158631177 homeodomain leucine zipper protein [Homo sapiens]         30   0.81 
gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]            30   1.1  
gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]         30   1.1  
gi|7657457 prostaglandin-D synthase [Homo sapiens]                     29   1.8  
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]           29   2.3  
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]            29   2.3  
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]          29   2.3  
gi|15431318 keratin 38 [Homo sapiens]                                  28   5.2  
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]           28   5.2  
gi|139394648 DNA polymerase theta [Homo sapiens]                       27   6.8  
gi|157502171 sorting nexin 19 [Homo sapiens]                           27   6.8  
gi|40548328 nascent-polypeptide-associated complex alpha polypep...    27   6.8  
gi|190194384 spermatogenesis associated 16 [Homo sapiens]              27   6.8  
gi|222144237 fibroblast growth factor receptor 2 isoform 6 precu...    27   8.9  
gi|222144235 fibroblast growth factor receptor 2 isoform 5 precu...    27   8.9  
gi|221316639 fibroblast growth factor receptor 2 isoform 1 precu...    27   8.9  
gi|4758484 glutathione-S-transferase omega 1 [Homo sapiens]            27   8.9  

>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
           sapiens]
          Length = 174

 Score =  351 bits (901), Expect = 2e-97
 Identities = 174/174 (100%), Positives = 174/174 (100%)

Query: 1   MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP 60
           MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP
Sbjct: 1   MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP 60

Query: 61  TLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMA 120
           TLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMA
Sbjct: 61  TLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMA 120

Query: 121 DLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 174
           DLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
Sbjct: 121 DLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 174


>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
          Length = 216

 Score =  331 bits (848), Expect = 2e-91
 Identities = 174/216 (80%), Positives = 174/216 (80%), Gaps = 42/216 (19%)

Query: 1   MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP 60
           MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP
Sbjct: 1   MQAGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVP 60

Query: 61  TLKIDGITIHQS------------------------------------------NLSVLK 78
           TLKIDGITIHQS                                          NLSVLK
Sbjct: 61  TLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLK 120

Query: 79  QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 138
           QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL
Sbjct: 121 QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180

Query: 139 TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 174
           TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
Sbjct: 181 TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 216


>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
          Length = 161

 Score =  220 bits (560), Expect = 6e-58
 Identities = 119/161 (73%), Positives = 119/161 (73%), Gaps = 42/161 (26%)

Query: 56  MKQVPTLKIDGITIHQS------------------------------------------N 73
           MKQVPTLKIDGITIHQS                                          N
Sbjct: 1   MKQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQN 60

Query: 74  LSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 133
           LSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER
Sbjct: 61  LSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAER 120

Query: 134 FKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 174
           FKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
Sbjct: 121 FKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 161


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 32.3 bits (72), Expect = 0.21
 Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 2/44 (4%)

Query: 29 IDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQS 72
          I +E   ++LIK  GQ  S  F  +NP+K+VP LK    T+ +S
Sbjct: 26 IPFELRIVDLIK--GQHLSDAFAQVNPLKKVPALKDGDFTLTES 67


>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
          Length = 222

 Score = 31.6 bits (70), Expect = 0.36
 Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 44/190 (23%)

Query: 3   AGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTL 62
           AGKP L+ +        +R  LA  G+++E   I   +D G+    D   +   +QVP +
Sbjct: 2   AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGK-LRNDGSLM--FQQVPMV 58

Query: 63  KIDGITIHQSNL------SVLKQVGEEMQLTWAQNAITCG-------------------- 96
           +IDG+ + Q+        S     G++++     +  T G                    
Sbjct: 59  EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118

Query: 97  --------------FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPY 141
                         F A E++LQS    Y VG++++ AD+ LV  +   E     L + +
Sbjct: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178

Query: 142 PTISSINKRL 151
           P + ++  R+
Sbjct: 179 PLLKALKTRI 188


>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
          Length = 550

 Score = 30.4 bits (67), Expect = 0.81
 Identities = 14/47 (29%), Positives = 25/47 (53%)

Query: 60  PTLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQS 106
           P  +  G++   + L  L  + EE+QL W Q A T   ++ E +L++
Sbjct: 27  PNKEASGLSSSPAGLICLPPISEELQLVWTQAAQTSELDSNEHLLKT 73


>gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]
          Length = 244

 Score = 30.0 bits (66), Expect = 1.1
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 14 SSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSN 73
          S  S  V I     GI  E   ++L+K  GQ  SK+F  +N + ++PTLK DG  I   +
Sbjct: 11 SQPSRAVYIFAKKNGIPLELRTVDLVK--GQHKSKEFLQINSLGKLPTLK-DGDFILTES 67

Query: 74 LSVL 77
           ++L
Sbjct: 68 SAIL 71


>gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]
          Length = 244

 Score = 30.0 bits (66), Expect = 1.1
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 14 SSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSN 73
          S  S  V I     GI  E   ++L+K  GQ  SK+F  +N + ++PTLK DG  I   +
Sbjct: 11 SQPSRAVYIFAKKNGIPLELRTVDLVK--GQHKSKEFLQINSLGKLPTLK-DGDFILTES 67

Query: 74 LSVL 77
           ++L
Sbjct: 68 SAIL 71


>gi|7657457 prostaglandin-D synthase [Homo sapiens]
          Length = 199

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 55  PMKQVPTLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQIL 104
           P  ++P L++DG+T+HQS L++ + + +   L        C  +A+   L
Sbjct: 47  PFGKIPILEVDGLTLHQS-LAIARYLTKNTDLAGNTEMEQCHVDAIVDTL 95


>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
          Length = 222

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 97  FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPYPTISSINKRL 151
           F A E++L+S    Y VG++++ AD+ LV  +   E     L + +P + ++  R+
Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRI 188


>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
          Length = 222

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 89  AQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQV-ANAERFKVDLTPYPTISSI 147
           AQ AI   F   E+IL+     + VG+++++AD+ L+  + A  E+    L+ +P +   
Sbjct: 125 AQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEY 184

Query: 148 NKRL 151
             +L
Sbjct: 185 TVKL 188


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 16/56 (28%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 97  FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPYPTISSINKRL 151
           F A E++L+S    Y VG++++ AD+ LV  +   E     L + +P + ++  R+
Sbjct: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRI 188


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 114 GDEVTMADLCLVPQVANAERFKVDLTP 140
           G E  +A +CL+  VA+A R +V  TP
Sbjct: 35  GAEANIAPMCLLANVAHANRVRVGSTP 61


>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
          Length = 222

 Score = 27.7 bits (60), Expect = 5.2
 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 97  FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL-TPYPTISSINKRL 151
           F A E++L+S    Y VG++++ AD+ LV      E     L + +P + ++  R+
Sbjct: 133 FPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKALKTRI 188


>gi|139394648 DNA polymerase theta [Homo sapiens]
          Length = 2590

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 110 IYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSI 147
           +  VG   T+ +L LV    NAE +  D  P P + S+
Sbjct: 259 VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESV 296


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 17/70 (24%), Positives = 35/70 (50%), Gaps = 15/70 (21%)

Query: 116 EVTMADLCLVPQVANAERFKVDLT------------PYPTISSINKRLL--VLEAFQVSH 161
           E  +  LC +P++AN+E  +  L             P+  +S I+K ++  +++  + + 
Sbjct: 634 ESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPF-MVSRIDKMVVSAIVDTLKTAF 692

Query: 162 PCRQPDTPTE 171
           P  +P +PTE
Sbjct: 693 PRSEPQSPTE 702


>gi|40548328 nascent-polypeptide-associated complex alpha
           polypeptide-like [Homo sapiens]
          Length = 215

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 18/65 (27%), Positives = 26/65 (40%)

Query: 72  SNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANA 131
           S L +L+  G      W    I      L+      +  Y V  E  + DL    Q+A A
Sbjct: 81  SKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQAQLAAA 140

Query: 132 ERFKV 136
           E+F+V
Sbjct: 141 EKFRV 145


>gi|190194384 spermatogenesis associated 16 [Homo sapiens]
          Length = 569

 Score = 27.3 bits (59), Expect = 6.8
 Identities = 16/47 (34%), Positives = 23/47 (48%)

Query: 128 VANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA 174
           +  AE F V  TP+ T    +K   V +AF  +HP       T+L+A
Sbjct: 318 ITRAESFSVMYTPFATKIRADKIEKVKDAFTKTHPAYAEYMYTDLQA 364


>gi|222144237 fibroblast growth factor receptor 2 isoform 6
           precursor [Homo sapiens]
          Length = 706

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 12/95 (12%)

Query: 66  GITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLV 125
           GI+ H + L+VL   G E ++T + + +        +I     G++ +   V    LC +
Sbjct: 234 GISFHSAWLTVLPAPGREKEITASPDYL--------EIAIYCIGVFLIACMVVTVILCRM 285

Query: 126 PQVANAERFKVDLTPYPTISSINKRLLVLEAFQVS 160
                    K D +  P +  + KR+ +     VS
Sbjct: 286 KNTTK----KPDFSSQPAVHKLTKRIPLRRQVTVS 316


>gi|222144235 fibroblast growth factor receptor 2 isoform 5
           precursor [Homo sapiens]
          Length = 707

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 12/95 (12%)

Query: 66  GITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLV 125
           GI+ H + L+VL   G E ++T + + +        +I     G++ +   V    LC +
Sbjct: 260 GISFHSAWLTVLPAPGREKEITASPDYL--------EIAIYCIGVFLIACMVVTVILCRM 311

Query: 126 PQVANAERFKVDLTPYPTISSINKRLLVLEAFQVS 160
                    K D +  P +  + KR+ +     VS
Sbjct: 312 KNTTK----KPDFSSQPAVHKLTKRIPLRRQVTVS 342


>gi|221316639 fibroblast growth factor receptor 2 isoform 1
           precursor [Homo sapiens]
          Length = 821

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 12/95 (12%)

Query: 66  GITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLV 125
           GI+ H + L+VL   G E ++T + + +        +I     G++ +   V    LC +
Sbjct: 349 GISFHSAWLTVLPAPGREKEITASPDYL--------EIAIYCIGVFLIACMVVTVILCRM 400

Query: 126 PQVANAERFKVDLTPYPTISSINKRLLVLEAFQVS 160
                    K D +  P +  + KR+ +     VS
Sbjct: 401 KNTTK----KPDFSSQPAVHKLTKRIPLRRQVTVS 431


>gi|4758484 glutathione-S-transferase omega 1 [Homo sapiens]
          Length = 241

 Score = 26.9 bits (58), Expect = 8.9
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)

Query: 19 RVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLK-IDGITIHQSNLS 75
          R R+ L  KGI +E + INL K+  + F K     NP   VP L+   G  I++S ++
Sbjct: 37 RTRLVLKAKGIRHEVININL-KNKPEWFFKK----NPFGLVPVLENSQGQLIYESAIT 89


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,321,964
Number of Sequences: 37866
Number of extensions: 235222
Number of successful extensions: 430
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 415
Number of HSP's gapped (non-prelim): 25
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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