BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like isoform 2 [Homo sapiens] (971 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i... 1967 0.0 gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like is... 1967 0.0 gi|190014623 DIS3 mitotic control isoform a [Homo sapiens] 509 e-144 gi|190014625 DIS3 mitotic control isoform b [Homo sapiens] 496 e-140 gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2... 284 2e-76 gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 130 8e-30 gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 130 8e-30 gi|224809295 xeroderma pigmentosum, complementation group C isof... 32 2.2 gi|239740946 PREDICTED: hypothetical protein XP_002344104 isofor... 32 2.9 gi|239740944 PREDICTED: hypothetical protein XP_002344105 isofor... 32 2.9 gi|239740942 PREDICTED: hypothetical protein XP_002344106 isofor... 32 2.9 gi|32698714 hypothetical protein LOC284058 [Homo sapiens] 32 2.9 gi|126032345 sterile alpha motif domain containing 3 isoform b [... 32 3.8 gi|126032305 sterile alpha motif domain containing 3 isoform a [... 32 3.8 gi|165905601 proline-serine-threonine phosphatase interacting pr... 31 4.9 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 31 6.4 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 31 6.4 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 30 8.4 gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 30 8.4 gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 30 8.4 >gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like isoform 1 [Homo sapiens] Length = 1054 Score = 1967 bits (5095), Expect = 0.0 Identities = 971/971 (100%), Positives = 971/971 (100%) Query: 1 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 60 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI Sbjct: 84 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 143 Query: 61 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 120 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC Sbjct: 144 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 203 Query: 121 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 180 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL Sbjct: 204 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 263 Query: 181 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 240 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE Sbjct: 264 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 323 Query: 241 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 300 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ Sbjct: 324 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 383 Query: 301 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 360 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM Sbjct: 384 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 443 Query: 361 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 420 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV Sbjct: 444 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 503 Query: 421 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 480 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW Sbjct: 504 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 563 Query: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE Sbjct: 564 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 623 Query: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE Sbjct: 624 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 683 Query: 601 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 660 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL Sbjct: 684 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 743 Query: 661 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 720 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS Sbjct: 744 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 803 Query: 721 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 780 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF Sbjct: 804 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 863 Query: 781 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 840 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP Sbjct: 864 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 923 Query: 841 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 900 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE Sbjct: 924 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 983 Query: 901 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 960 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL Sbjct: 984 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 1043 Query: 961 ALLDVSNNYGI 971 ALLDVSNNYGI Sbjct: 1044 ALLDVSNNYGI 1054 >gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like isoform 2 [Homo sapiens] Length = 971 Score = 1967 bits (5095), Expect = 0.0 Identities = 971/971 (100%), Positives = 971/971 (100%) Query: 1 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 60 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI Sbjct: 1 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 60 Query: 61 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 120 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC Sbjct: 61 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 120 Query: 121 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 180 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL Sbjct: 121 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 180 Query: 181 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 240 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE Sbjct: 181 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 240 Query: 241 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 300 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ Sbjct: 241 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 300 Query: 301 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 360 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM Sbjct: 301 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 360 Query: 361 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 420 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV Sbjct: 361 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 420 Query: 421 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 480 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW Sbjct: 421 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 480 Query: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE Sbjct: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540 Query: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE Sbjct: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600 Query: 601 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 660 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL Sbjct: 601 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 660 Query: 661 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 720 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS Sbjct: 661 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 720 Query: 721 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 780 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF Sbjct: 721 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 780 Query: 781 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 840 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP Sbjct: 781 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 840 Query: 841 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 900 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE Sbjct: 841 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 900 Query: 901 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 960 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL Sbjct: 901 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 960 Query: 961 ALLDVSNNYGI 971 ALLDVSNNYGI Sbjct: 961 ALLDVSNNYGI 971 >gi|190014623 DIS3 mitotic control isoform a [Homo sapiens] Length = 958 Score = 509 bits (1310), Expect = e-144 Identities = 327/915 (35%), Positives = 499/915 (54%), Gaps = 103/915 (11%) Query: 1 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 60 +QT Q V++ R Y ++R++ + F NE + Y+ +E+GE+ R+I Sbjct: 91 LQTVLQEVRN-RSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAI 149 Query: 61 YNAAVWYYHHCQ-----DRMPIVMVTED----EEAIQQYGSETEGVFVITFKNYLDNFWP 111 AA WY H + +++ ++ +T D E+AI+ EG+ T + Y+ + Sbjct: 150 RVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIE------EGIPAFTCEEYVKS--- 200 Query: 112 DLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHR 171 L A EL D + + E ES + EHLPL L+ GIKSG Y+QG ++ Sbjct: 201 -LTANPELIDRL--ACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASREN 257 Query: 172 AQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCEN 231 +EA V + G D++ +I++ G+K NR++H D+V VELLPK++W + + + Sbjct: 258 -YLEATVWIHG----DNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHD 312 Query: 232 DCDDKASGESPSEP-------------MPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKN 278 + ++ E E PTGRVVGI+++NWR Y SK ++ K Sbjct: 313 EGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML-SKSDI----KE 367 Query: 279 AQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLE 338 +++ L TP D RIP+IRI T+QA TL+ R++V ID W S YPNGHFVR LG +G+ E Sbjct: 368 SRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKE 427 Query: 339 GEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHL-VFSIDPK 397 E +L+E+ + PFS+A + +P + PW ++ ++ + R+DLR HL + S+DP Sbjct: 428 TETEVLLLEHDVPHQPFSQAVLSFLP----KMPWSITEKDMKNREDLR--HLCICSVDPP 481 Query: 398 GCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLP 457 GC D+DD L R L NGNLE+GVHIADV+HF+ P + +D E+ R TT YL ++R DM+P Sbjct: 482 GCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVP 541 Query: 458 SVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGN 517 +LS++LCSL VDR A S +WE++ + EI K + +++I S L Y AQ +D + Sbjct: 542 ELLSSNLCSLKCDVDRLAFSCIWEMNH-NAEILKTKFTKSVINSKASLTYAEAQLRID-S 599 Query: 518 LSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQL 577 ++ DDI ++ L +A+ ++ +R GAL L EV + Sbjct: 600 ANMNDDI------------------TTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHM 641 Query: 578 DDKKNIHDLIPKQPLEVHET---VAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFF 634 D + HD I Q E+ ET V E M+LAN VAKKI E F ALLR+HP P + Sbjct: 642 DSE--THDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNY 699 Query: 635 SELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSC 694 L + A+++ I T + K+LA+SLD A P P +N LLR +AT+ M A+YF +G Sbjct: 700 EILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSG-- 757 Query: 695 AEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELC 754 + +FHHYGLA YTHFTSPIRRY+D++VHRLL AI D L L ++C Sbjct: 758 MDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYP---ELTDKHKLADIC 814 Query: 755 RHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGI 814 +++N R++ AQ++Q+ S ++FK K +EE I +R N +++ IP++G+ Sbjct: 815 KNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEE-----AYILFVRKNAIVVLIPKYGL 869 Query: 815 KGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISI 874 +G + + KD KP + ++I S E FH+FD V V+I + Sbjct: 870 EGTVFFEEKD--------------KPNPQLIYDDEIPSLKI--EDTVFHVFDKVKVKIML 913 Query: 875 QASRCHSDTIRLEII 889 +S IR+ ++ Sbjct: 914 DSSNLQHQKIRMSLV 928 >gi|190014625 DIS3 mitotic control isoform b [Homo sapiens] Length = 928 Score = 496 bits (1278), Expect = e-140 Identities = 317/873 (36%), Positives = 480/873 (54%), Gaps = 102/873 (11%) Query: 43 YLPRERGESMEKWQTRSIYNAAVWYYHHCQ-----DRMPIVMVTED----EEAIQQYGSE 93 Y+ +E+GE+ R+I AA WY H + +++ ++ +T D E+AI+ Sbjct: 102 YVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIE----- 156 Query: 94 TEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEA 153 EG+ T + Y+ + L A EL D + + E ES + EHLPL L+ Sbjct: 157 -EGIPAFTCEEYVKS----LTANPELIDRL--ACLSEEGNEIESGKIIFSEHLPLSKLQQ 209 Query: 154 GIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVV 213 GIKSG Y+QG ++ +EA V + G D++ +I++ G+K NR++H D+V V Sbjct: 210 GIKSGTYLQGTFRASREN-YLEATVWIHG----DNEENKEIILQGLKHLNRAVHEDIVAV 264 Query: 214 ELLPKNEWKGRTVALCENDCDDKASGESPSEP-------------MPTGRVVGILQKNWR 260 ELLPK++W + + ++ ++ E E PTGRVVGI+++NWR Sbjct: 265 ELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWR 324 Query: 261 DYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTS 320 Y SK ++ K +++ L TP D RIP+IRI T+QA TL+ R++V ID W S Sbjct: 325 PYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNS 379 Query: 321 VYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQ 380 YPNGHFVR LG +G+ E E +L+E+ + PFS+A + +P + PW ++ ++ + Sbjct: 380 RYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP----KMPWSITEKDMK 435 Query: 381 KRKDLRKSHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEA 439 R+DLR HL + S+DP GC D+DD L R L NGNLE+GVHIADV+HF+ P + +D E+ Sbjct: 436 NREDLR--HLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQES 493 Query: 440 RTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTII 499 R TT YL ++R DM+P +LS++LCSL VDR A S +WE++ + EI K + +++I Sbjct: 494 ARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNH-NAEILKTKFTKSVI 552 Query: 500 RSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAK 559 S L Y AQ +D + ++ DDI ++ L +A+ ++ + Sbjct: 553 NSKASLTYAEAQLRID-SANMNDDI------------------TTSLRGLNKLAKILKKR 593 Query: 560 RDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHET---VAECMILANHWVAKKIWES 616 R GAL L EV +D + HD I Q E+ ET V E M+LAN VAKKI E Sbjct: 594 RIEKGALTLSSPEVRFHMDSE--THDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEE 651 Query: 617 FPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLR 676 F ALLR+HP P + L + A+++ I T + K+LA+SLD A P P +N LLR Sbjct: 652 FSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLR 711 Query: 677 SMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDK 736 +AT+ M A+YF +G + +FHHYGLA YTHFTSPIRRY+D++VHRLL AI D Sbjct: 712 ILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADC 769 Query: 737 KMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGV 796 L L ++C+++N R++ AQ++Q+ S ++FK K +EE Sbjct: 770 TYP---ELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEE-----AY 821 Query: 797 IYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTD 856 I +R N +++ IP++G++G + + KD KP + ++I S Sbjct: 822 ILFVRKNAIVVLIPKYGLEGTVFFEEKD--------------KPNPQLIYDDEIPSLKI- 866 Query: 857 GESVTFHLFDHVTVRISIQASRCHSDTIRLEII 889 E FH+FD V V+I + +S IR+ ++ Sbjct: 867 -EDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 898 >gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2 [Homo sapiens] Length = 885 Score = 284 bits (727), Expect = 2e-76 Identities = 225/746 (30%), Positives = 362/746 (48%), Gaps = 79/746 (10%) Query: 131 ENESQESHGKEYPE-----HLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASS 185 + E++ ++ + PE HLP + L++ S I +EA + G+ S Sbjct: 130 DKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVI------------VEA--QFDGSDS 175 Query: 186 KDSD-LVSDILIHGMKARNRSIH------GDVVVVELLPKNEWKGRTVALCENDCDDKAS 238 +D + ++L+ G+K + + GD V K T + + D +A Sbjct: 176 EDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVT--------KDETTCISQ---DTRAL 224 Query: 239 GESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRIST 298 E + + +VV IL+K F ++ + L +P D+R+P+I + Sbjct: 225 SEKSLQR--SAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSPSDHRVPRIYVPL 282 Query: 299 QQAETLQDFRV----------VVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVEN 348 + QDF + RI W+ + G + LG+ G++E E IL E Sbjct: 283 KDCP--QDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEY 340 Query: 349 SISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSV 408 + FS + +P P W + PEE KR+DLRK +F+IDP D+DD LS Sbjct: 341 GVDFSDFSSEVLECLPQGLP---WTIPPEEFSKRRDLRKD-CIFTIDPSTARDLDDALSC 396 Query: 409 RTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLL 468 + L +GN ++GVHIADV++FV S +D A RAT+ YL + MLP +L +LCSL Sbjct: 397 KPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLN 456 Query: 469 GGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFK 528 D+ S++W L +I W+GRTIIRS KL YE AQ +++ S + IP K Sbjct: 457 PMSDKLTFSVIWTLTPEG-KILDEWFGRTIIRSCTKLSYEHAQSMIE---SPTEKIPA-K 511 Query: 529 DLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-HDLI 587 +L S + EE+ A+ L IA+ +R +R GAL L+ +++ LD + + Sbjct: 512 ELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCH 571 Query: 588 PKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFF 647 + E ++ V E M+LAN VA KI +FP QALLR+HPPP S+L E G Sbjct: 572 IYEYRESNKLVEEFMLLANMAVAHKIHRAFPEQALLRRHPPPQTRMLSDLVEFCDQMGLP 631 Query: 648 IDTRSNKTLADSLDN--ANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAE-EEFHHYGL 704 +D S L SL +D + +L +M ++ M ALYF +G + +F HY L Sbjct: 632 VDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSGLLQDPAQFRHYAL 691 Query: 705 ALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAA 764 + YTHFTSPIRR++D++VHRLL AA+ +++++ + L++ H N+R A+ Sbjct: 692 NVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDM-----APDTLQKQADHCNDRRMAS 746 Query: 765 QHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY----- 819 + Q+ ST LF + K+ P S+ ++ I + + R+G++ Y Sbjct: 747 KRVQELSTSLFFAVLVKESGPLE-----SEAMVMGILKQAFDVLVLRYGVQKRIYCNALA 801 Query: 820 LKNKDGLVISCGPDSCSEWKPGSLQR 845 L++ + P+ W+P +++ Sbjct: 802 LRSHHFQKVGKKPELTLVWEPEDMEQ 827 Score = 63.2 bits (152), Expect = 1e-09 Identities = 41/116 (35%), Positives = 69/116 (59%), Gaps = 13/116 (11%) Query: 129 ERENESQESHGKE---YPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASS 185 +++++++ + GK+ + ++ E + G+K G IQG+L +N + EAF+ S Sbjct: 34 DKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFH-EAFI-----PS 87 Query: 186 KDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGES 241 D D DI I G+ ARNR+++GD+VVV+LLP+ WK V ND + +A+ ES Sbjct: 88 PDGD--RDIFIDGVVARNRALNGDLVVVKLLPEEHWK--VVKPESNDKETEAAYES 139 >gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1 [Homo sapiens] Length = 2649 Score = 130 bits (326), Expect = 8e-30 Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%) Query: 194 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 243 I + G + GD V+V+LL P+ +GR + + + + A P Sbjct: 1155 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 1214 Query: 244 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 302 +P G V I +D PS+ + S K R+ ++ + AE Sbjct: 1215 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 1258 Query: 303 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 362 V+I W YP G VL E + + +E S+ V P +A + + Sbjct: 1259 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 1318 Query: 363 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 422 + +V+ E R + L F++DP+G ++DD LSVR L E+ VHI Sbjct: 1319 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 1372 Query: 423 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 481 DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+ Sbjct: 1373 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 1432 Query: 482 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 541 ++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++ Sbjct: 1433 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 1484 Query: 542 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 596 V A + + R R + D C Q D+ + H ++ + ++ + Sbjct: 1485 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534 Query: 597 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 631 VAE ++ V W+ P +AL +H PP Sbjct: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594 Query: 632 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 691 L K F T+ + + D L +D H P + R + +A Sbjct: 1595 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1647 Query: 692 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 748 G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S + Sbjct: 1648 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1701 Query: 749 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 781 D++ LC+ + ++ AQ Q+++ L + K Sbjct: 1702 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1734 >gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2 [Homo sapiens] Length = 2080 Score = 130 bits (326), Expect = 8e-30 Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%) Query: 194 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 243 I + G + GD V+V+LL P+ +GR + + + + A P Sbjct: 586 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 645 Query: 244 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 302 +P G V I +D PS+ + S K R+ ++ + AE Sbjct: 646 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 689 Query: 303 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 362 V+I W YP G VL E + + +E S+ V P +A + + Sbjct: 690 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 749 Query: 363 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 422 + +V+ E R + L F++DP+G ++DD LSVR L E+ VHI Sbjct: 750 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 803 Query: 423 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 481 DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+ Sbjct: 804 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 863 Query: 482 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 541 ++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++ Sbjct: 864 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 915 Query: 542 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 596 V A + + R R + D C Q D+ + H ++ + ++ + Sbjct: 916 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965 Query: 597 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 631 VAE ++ V W+ P +AL +H PP Sbjct: 966 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025 Query: 632 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 691 L K F T+ + + D L +D H P + R + +A Sbjct: 1026 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1078 Query: 692 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 748 G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S + Sbjct: 1079 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1132 Query: 749 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 781 D++ LC+ + ++ AQ Q+++ L + K Sbjct: 1133 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1165 >gi|224809295 xeroderma pigmentosum, complementation group C isoform 1 [Homo sapiens] Length = 940 Score = 32.3 bits (72), Expect = 2.2 Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 2/113 (1%) Query: 106 LDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGIL 165 L +F DLK AH L + E E + + E E L VL +S + + +L Sbjct: 99 LRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLL 158 Query: 166 NVNKHRAQIEA--FVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELL 216 V +IE + + S K L MK N+ +H D V LL Sbjct: 159 PVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLL 211 >gi|239740946 PREDICTED: hypothetical protein XP_002344104 isoform 1 [Homo sapiens] Length = 430 Score = 32.0 bits (71), Expect = 2.9 Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%) Query: 705 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 759 ALD T T+ +RR +DI + + L +K + I+ L LE+ + N Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334 Query: 760 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 819 SQ T + K A E S+G+ +++N + + RF G A Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390 Query: 820 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 859 L+ CSE Q F + +T +++ GES Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411 >gi|239740944 PREDICTED: hypothetical protein XP_002344105 isoform 2 [Homo sapiens] Length = 430 Score = 32.0 bits (71), Expect = 2.9 Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%) Query: 705 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 759 ALD T T+ +RR +DI + + L +K + I+ L LE+ + N Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334 Query: 760 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 819 SQ T + K A E S+G+ +++N + + RF G A Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390 Query: 820 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 859 L+ CSE Q F + +T +++ GES Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411 >gi|239740942 PREDICTED: hypothetical protein XP_002344106 isoform 3 [Homo sapiens] Length = 430 Score = 32.0 bits (71), Expect = 2.9 Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%) Query: 705 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 759 ALD T T+ +RR +DI + + L +K + I+ L LE+ + N Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334 Query: 760 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 819 SQ T + K A E S+G+ +++N + + RF G A Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390 Query: 820 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 859 L+ CSE Q F + +T +++ GES Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411 >gi|32698714 hypothetical protein LOC284058 [Homo sapiens] Length = 1105 Score = 32.0 bits (71), Expect = 2.9 Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%) Query: 705 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 759 ALD T T+ +RR +DI + + L +K + I+ L LE+ + N Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334 Query: 760 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 819 SQ T + K A E S+G+ +++N + + RF G A Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390 Query: 820 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 859 L+ CSE Q F + +T +++ GES Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411 >gi|126032345 sterile alpha motif domain containing 3 isoform b [Homo sapiens] Length = 221 Score = 31.6 bits (70), Expect = 3.8 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 19/145 (13%) Query: 39 QQCCYLPRER-GESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDE------EAIQQYG 91 Q C +L + GE + ++Q + AA+ + DRM +V + + I++Y Sbjct: 8 QVCSWLVEKNLGELVHRFQEEEVSGAALLALN---DRMVQQLVKKIGHQAVLMDLIKKYK 64 Query: 92 SETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVL 151 T+G L + KAA + + R+ E+ S HG++ P P E L Sbjct: 65 QNTQG---------LKSPENPKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENL 115 Query: 152 EAGIKSGRYIQGILNVNKHRAQIEA 176 + G+ R ++ NV + A+ +A Sbjct: 116 DNGLIDQRVLKQRRNVKQILARSKA 140 >gi|126032305 sterile alpha motif domain containing 3 isoform a [Homo sapiens] Length = 520 Score = 31.6 bits (70), Expect = 3.8 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 19/145 (13%) Query: 39 QQCCYLPRER-GESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDE------EAIQQYG 91 Q C +L + GE + ++Q + AA+ + DRM +V + + I++Y Sbjct: 8 QVCSWLVEKNLGELVHRFQEEEVSGAALLALN---DRMVQQLVKKIGHQAVLMDLIKKYK 64 Query: 92 SETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVL 151 T+G L + KAA + + R+ E+ S HG++ P P E L Sbjct: 65 QNTQG---------LKSPENPKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENL 115 Query: 152 EAGIKSGRYIQGILNVNKHRAQIEA 176 + G+ R ++ NV + A+ +A Sbjct: 116 DNGLIDQRVLKQRRNVKQILARSKA 140 >gi|165905601 proline-serine-threonine phosphatase interacting protein 2 [Homo sapiens] Length = 334 Score = 31.2 bits (69), Expect = 4.9 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 727 LLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHS-----QKQSTELF 775 L+M AI K K ++ K + + K+ E+ CR + QA S KQ +LF Sbjct: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLF 174 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 30.8 bits (68), Expect = 6.4 Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 20/154 (12%) Query: 821 KNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHL-----------FDHVT 869 K L I+C E + L+R K+ T +++TF L +++ Sbjct: 646 KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705 Query: 870 VRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKS-ELVKEVTKSVEEAQLAQ 928 +R ++++ +C S + ++ N EL + L K EL+K K E +++ Sbjct: 706 LRRNVESLKCAS-------MKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758 Query: 929 EVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLAL 962 + ++I + Q+ + + + L E++DL + Sbjct: 759 Q-GLDIENQRLQKTLENSNKKIQQLESELQDLEM 791 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 30.8 bits (68), Expect = 6.4 Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 20/154 (12%) Query: 821 KNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHL-----------FDHVT 869 K L I+C E + L+R K+ T +++TF L +++ Sbjct: 646 KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705 Query: 870 VRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKS-ELVKEVTKSVEEAQLAQ 928 +R ++++ +C S + ++ N EL + L K EL+K K E +++ Sbjct: 706 LRRNVESLKCAS-------MKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758 Query: 929 EVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLAL 962 + ++I + Q+ + + + L E++DL + Sbjct: 759 Q-GLDIENQRLQKTLENSNKKIQQLESELQDLEM 791 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 30.4 bits (67), Expect = 8.4 Identities = 18/78 (23%), Positives = 36/78 (46%) Query: 885 RLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQ 944 R + I + ++ + + + L + E + + EE +L QE K + QE+ Q Sbjct: 571 RRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQ 630 Query: 945 TKGRSLYTLLEEIRDLAL 962 K +++ LE+I+ L Sbjct: 631 IKKKTVRERLEQIKKTEL 648 >gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 isoform b [Homo sapiens] Length = 422 Score = 30.4 bits (67), Expect = 8.4 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%) Query: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540 E +K+ YE+ V G ++R+ ++ E+ D +IP D SR + Sbjct: 72 ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIP---DKGRFSRTNIIS 128 Query: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600 +L I +LT I + RD A +L E+ ++ + K + ++ E HE AE Sbjct: 129 DLEEQISELTAIIEQM--NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE--AE 184 Query: 601 CMILANHWVAKKIWESFPHQALLRQ 625 L N++ A E Q L + Sbjct: 185 LSELENNYKAALKAEKLAAQEKLEE 209 >gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 isoform a [Homo sapiens] Length = 445 Score = 30.4 bits (67), Expect = 8.4 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%) Query: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540 E +K+ YE+ V G ++R+ ++ E+ D +IP D SR + Sbjct: 72 ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIP---DKGRFSRTNIIS 128 Query: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600 +L I +LT I + RD A +L E+ ++ + K + ++ E HE AE Sbjct: 129 DLEEQISELTAIIEQM--NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE--AE 184 Query: 601 CMILANHWVAKKIWESFPHQALLRQ 625 L N++ A E Q L + Sbjct: 185 LSELENNYKAALKAEKLAAQEKLEE 209 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,491,174 Number of Sequences: 37866 Number of extensions: 1616326 Number of successful extensions: 4588 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 4533 Number of HSP's gapped (non-prelim): 31 length of query: 971 length of database: 18,247,518 effective HSP length: 112 effective length of query: 859 effective length of database: 14,006,526 effective search space: 12031605834 effective search space used: 12031605834 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.