Search of human proteins with 190360571

Search of human proteins with 190360571

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190360571 cytosolic beta-glucosidase isoform b [Homo
sapiens]
         (162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190360571 cytosolic beta-glucosidase isoform b [Homo sapiens]      350   2e-97
gi|13273313 cytosolic beta-glucosidase isoform a [Homo sapiens]       212   1e-55
gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapi...   119   1e-27
gi|110681710 lactase-like [Homo sapiens]                              115   2e-26
gi|24497614 klotho [Homo sapiens]                                     102   2e-22
gi|28376633 klotho beta [Homo sapiens]                                 84   4e-17
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]               27   5.9  
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           27   7.7  
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          27   7.7  

>gi|190360571 cytosolic beta-glucosidase isoform b [Homo sapiens]
          Length = 162

 Score =  350 bits (899), Expect = 2e-97
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 1   MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
           MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE
Sbjct: 1   MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60

Query: 61  EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQ 120
           EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQ
Sbjct: 61  EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQ 120

Query: 121 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 162
           GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
Sbjct: 121 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 162


>gi|13273313 cytosolic beta-glucosidase isoform a [Homo sapiens]
          Length = 469

 Score =  212 bits (540), Expect = 1e-55
 Identities = 96/97 (98%), Positives = 96/97 (98%)

Query: 1  MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
          MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE
Sbjct: 1  MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60

Query: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
          EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQK I
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGI 97



 Score =  146 bits (368), Expect = 9e-36
 Identities = 68/68 (100%), Positives = 68/68 (100%)

Query: 95  KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 154
           KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR
Sbjct: 402 KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 461

Query: 155 NNGLEAHL 162
           NNGLEAHL
Sbjct: 462 NNGLEAHL 469


>gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapiens]
          Length = 1927

 Score =  119 bits (297), Expect = 1e-27
 Identities = 55/95 (57%), Positives = 70/95 (73%), Gaps = 1/95 (1%)

Query: 3    FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
            FP GF W+AA+AAYQ+EG W ADGKG  +WDTF+H    RV  +  GDVAC SY    ED
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHTP-LRVENDAIGDVACDSYHKIAED 1435

Query: 63   LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
            L  ++ LG++HYRFS+SWSR+LPDGTT +IN+  +
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGL 1470



 Score =  106 bits (265), Expect = 8e-24
 Identities = 46/95 (48%), Positives = 59/95 (62%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
           F   F W  +++AYQ+EG WDADGKGP +WD FTH  G  V  N TGD+AC SY   + D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
           L  ++ L +  YRFS+SWSR+ P G    IN   +
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGV 997



 Score = 80.9 bits (198), Expect = 4e-16
 Identities = 36/70 (51%), Positives = 51/70 (72%), Gaps = 2/70 (2%)

Query: 91   FINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 148
            +IN+  KA +LD ++L+ Y AWSL+DNFEW  GY+ +FGL+HVDF +  RPR    SA+ 
Sbjct: 1295 YINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARY 1354

Query: 149  YAKIIRNNGL 158
            Y ++I NNG+
Sbjct: 1355 YTEVITNNGM 1364



 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 37/69 (53%), Positives = 50/69 (72%), Gaps = 3/69 (4%)

Query: 91   FINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 148
            +IN+  KA+Q DKV+L+ Y  WS +DNFEW  G+S RFGL  V++ DP+ PR+P  SAK 
Sbjct: 1772 YINEALKAVQ-DKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKF 1830

Query: 149  YAKIIRNNG 157
            YA ++R NG
Sbjct: 1831 YASVVRCNG 1839



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 33/69 (47%), Positives = 44/69 (63%), Gaps = 2/69 (2%)

Query: 91  FINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 148
           +IN+  KAI+ D V+++ Y A SL+D FE   GYS RFGL HV+F D ++ R P  SA  
Sbjct: 778 YINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYF 837

Query: 149 YAKIIRNNG 157
           +  II  NG
Sbjct: 838 FTSIIEKNG 846



 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
           FP GF W A+T A+ VEGGW   G+G  +WD    +         T +VA  SY     D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD--PRRPLNTTEGQATLEVASDSYHKVASD 439

Query: 63  LKCIKQLGLTHYRFSLSWSRLLPDG 87
           +  +  L    Y+FS+SWSR+ P G
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMG 464



 Score = 33.5 bits (75), Expect = 0.082
 Identities = 13/28 (46%), Positives = 21/28 (75%)

Query: 71  LTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
           +THY+  LSW++LLP G+T   ++K +Q
Sbjct: 84  ITHYKVFLSWAQLLPAGSTQNPDEKTVQ 111


>gi|110681710 lactase-like [Homo sapiens]
          Length = 567

 Score =  115 bits (287), Expect = 2e-26
 Identities = 51/105 (48%), Positives = 67/105 (63%), Gaps = 6/105 (5%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
           FP GF W   ++AYQ EG WD DGKGP +WD FTH G  +V  N+T DVAC  Y   +ED
Sbjct: 37  FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96

Query: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVY 107
           +  +++L + HYRFSLSW RLLP G       +A Q++K  ++ Y
Sbjct: 97  IILLRELHVNHYRFSLSWPRLLPTGI------RAEQVNKKGIEFY 135



 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 35/70 (50%), Positives = 48/70 (68%), Gaps = 3/70 (4%)

Query: 90  GFINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAK 147
           G+IN+  KAI+ D  N++ Y +WSLLD FEW +GYS R+G ++V+F D  +PR P  S +
Sbjct: 434 GYINEMLKAIK-DGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQ 492

Query: 148 EYAKIIRNNG 157
            Y KII  NG
Sbjct: 493 YYKKIIIANG 502


>gi|24497614 klotho [Homo sapiens]
          Length = 1012

 Score =  102 bits (253), Expect = 2e-22
 Identities = 48/111 (43%), Positives = 65/111 (58%), Gaps = 15/111 (13%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQ---------------GGERVFKNQ 47
           FP GF WA  +AAYQ EGGW   GKG  +WDTFTH                G     +  
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 48  TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
           TGDVA  SY     D + +++LG+THYRFS+SW+R+LP+G+ G  N++ ++
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLR 171



 Score = 68.2 bits (165), Expect = 3e-12
 Identities = 33/63 (52%), Positives = 44/63 (69%)

Query: 95  KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIR 154
           KAI+LD V++  Y AWSL+D FEW++GYS R GLF+VDF    +  +P +SA  Y K+I 
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502

Query: 155 NNG 157
            NG
Sbjct: 503 KNG 505



 Score = 36.2 bits (82), Expect = 0.013
 Identities = 13/46 (28%), Positives = 26/46 (56%)

Query: 53  CGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
           C  +   +  +  ++++ +TH+RFSL W+ +LP G    +N   +Q
Sbjct: 572 CVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQ 617



 Score = 30.4 bits (67), Expect = 0.70
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 12/69 (17%)

Query: 91  FINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKE 148
           +IN+  KA  LD +NL  Y A+S      +N   + RFGL+       A    P  S K 
Sbjct: 894 YINEALKAHILDGINLCGYFAYS------FNDRTAPRFGLYRY----AADQFEPKASMKH 943

Query: 149 YAKIIRNNG 157
           Y KII +NG
Sbjct: 944 YRKIIDSNG 952


>gi|28376633 klotho beta [Homo sapiens]
          Length = 1044

 Score = 84.3 bits (207), Expect = 4e-17
 Identities = 40/96 (41%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
           FP  F W   T A QVEG W  DGKGP +WD F H   + V    + + +  SY   E+D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYIFLEKD 137

Query: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
           L  +  +G++ Y+FS+SW RL PDG     N K +Q
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQ 173



 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 8/85 (9%)

Query: 81  SRLLPDGTTG------FINQ--KAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVD 132
           SR+  + TT       F++Q  +AI+LD++ +  Y AWSLLD FEW   Y+ R GLF+VD
Sbjct: 423 SRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVD 482

Query: 133 FEDPARPRVPYTSAKEYAKIIRNNG 157
           F    + R P +SA  Y +IIR NG
Sbjct: 483 FNSKQKERKPKSSAHYYKQIIRENG 507



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 3   FPAGFGWAAATAAYQVEGGWDADGKGP---CVWDTFTHQGGERV--FKNQTGDVACGSYT 57
           FP  F W    +  + E    +         VW+   ++   RV   + +T    C  + 
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 580

Query: 58  LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
             ++ L+ + ++ +THYRF+L W+ +LP G    +N++A++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALR 621


>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
          Length = 848

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 18/82 (21%)

Query: 58  LWEEDLKCIKQLGLTHYRFSLSWSRLLPD------GTTGFINQKAIQLDKVNLQVYCAWS 111
           LW       K L ++    SL+W++  PD      G  GF  QK          + C WS
Sbjct: 475 LWSFSCDLTKGLNVS----SLAWNKTNPDLLAVGYGHFGFKEQKR--------GLACCWS 522

Query: 112 LLDNFEWNQGYSSRFGLFHVDF 133
           + +     + Y S +G+  VDF
Sbjct: 523 IKNPMWPERIYQSPYGVTAVDF 544


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 3/42 (7%)

Query: 8   GWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
           G+  +    +  GG+D DG+GP    +   +GG   FKN  G
Sbjct: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGG---FKNFGG 211


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 3/42 (7%)

Query: 8   GWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
           G+  +    +  GG+D DG+GP    +   +GG   FKN  G
Sbjct: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGG---FKNFGG 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.461 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,065,265
Number of Sequences: 37866
Number of extensions: 313308
Number of successful extensions: 559
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 536
Number of HSP's gapped (non-prelim): 22
length of query: 162
length of database: 18,247,518
effective HSP length: 94
effective length of query: 68
effective length of database: 14,688,114
effective search space: 998791752
effective search space used: 998791752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.