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Search of human proteins with 189571671
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189571671 sprouty-related protein with EVH-1 domain 2
isoform b [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform... 891 0.0
gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform... 882 0.0
gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa... 424 e-118
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 272 5e-73
gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b ... 134 1e-31
gi|27501452 sprouty homolog 3 [Homo sapiens] 70 3e-12
gi|56549694 enabled homolog isoform a [Homo sapiens] 68 1e-11
gi|39930375 enabled homolog isoform b [Homo sapiens] 68 1e-11
gi|7706687 Enah/Vasp-like [Homo sapiens] 63 4e-10
gi|5032115 sprouty 2 [Homo sapiens] 62 1e-09
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 60 4e-09
gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo... 60 5e-09
gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo... 60 5e-09
gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens] 59 1e-08
gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens] 59 1e-08
gi|14210518 PAR-6 gamma protein [Homo sapiens] 39 0.007
gi|7662022 lipin 2 [Homo sapiens] 33 0.62
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti... 32 0.81
gi|239750462 PREDICTED: similar to hCG2033802 [Homo sapiens] 32 1.1
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 31 2.4
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 31 2.4
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 31 2.4
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 31 2.4
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 31 2.4
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 31 2.4
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 31 2.4
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 31 2.4
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 30 3.1
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 30 3.1
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 30 4.0
>gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b
[Homo sapiens]
Length = 415
Score = 891 bits (2302), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MASPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGER 60
MASPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGER
Sbjct: 1 MASPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGER 60
Query: 61 QKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLI 120
QKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLI
Sbjct: 61 QKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLI 120
Query: 121 EGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHL 180
EGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHL
Sbjct: 121 EGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHL 180
Query: 181 HDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDP 240
HDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDP
Sbjct: 181 HDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDP 240
Query: 241 SEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKED 300
SEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKED
Sbjct: 241 SEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKED 300
Query: 301 GERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD 360
GERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD
Sbjct: 301 GERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD 360
Query: 361 PCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 415
PCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
Sbjct: 361 PCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 415
>gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a
[Homo sapiens]
Length = 418
Score = 882 bits (2278), Expect = 0.0
Identities = 410/412 (99%), Positives = 410/412 (99%)
Query: 4 PGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD 63
P DSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD
Sbjct: 7 PDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD 66
Query: 64 KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS 123
KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS
Sbjct: 67 KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS 126
Query: 124 TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS 183
TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS
Sbjct: 127 TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS 186
Query: 184 YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED 243
YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED
Sbjct: 187 YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED 246
Query: 244 ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER 303
ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER
Sbjct: 247 ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER 306
Query: 304 SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS 363
SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS
Sbjct: 307 SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS 366
Query: 364 CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 415
CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
Sbjct: 367 CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 418
>gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo
sapiens]
Length = 444
Score = 424 bits (1089), Expect = e-118
Identities = 233/452 (51%), Positives = 285/452 (63%), Gaps = 53/452 (11%)
Query: 2 ASPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQ 61
A+ +D+ RV+AVVMTRDDSSGGW P G G+S V V KV H E NG + F I GER
Sbjct: 6 ATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFIRGERL 65
Query: 62 KDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIE 121
+DK+VVLEC ++KDL+Y K PTFHHWK+D++KFGLTFQSPADARAFDRG+R+AIED+ +
Sbjct: 66 RDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISQ 125
Query: 122 GSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKR--EQPTRTISSPTSCEH-------- 171
G S NEAE G DD+ DSSS+ + +Q T S P +
Sbjct: 126 GCPESK----NEAE-GADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRPSPFED 180
Query: 172 ---RRIYTLGHLHD----------------------SYPTDHYHLDQPMP-RPYRQVSFP 205
RR+Y + S +P + R VSF
Sbjct: 181 LNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIRHVSFQ 240
Query: 206 DDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSEDADSSYVRFAKGEVPKHDYNYPY 265
D+DE IVRINPR+ I + Y DYRH P K +DADSS ++F+K + K DY Y
Sbjct: 241 DEDE-IVRINPRD-ILIRRYADYRH-PDMWKNDLERDDADSS-IQFSKPDSKKSDYLYSC 296
Query: 266 VDSSDFGLGEDPKGRGGSVIKTQPSR---GKSRRRKEDGERSRCVYCRDMFNHEENRRGH 322
D + +D V KTQPS KS+RRKEDGERSRCVYC++ FNHEEN RG
Sbjct: 297 GDETKLSSPKD-----SVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEENVRGK 351
Query: 323 CQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALS 382
CQDAPD ++ CI +VSCM CA+SMLYHCMSD EGD++DPCSCDTSD+KFCLRW+AL+ALS
Sbjct: 352 CQDAPDPIKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALS 411
Query: 383 FLAPCMCCYLPLRACYHCGVMCRCCGGKHKAA 414
F+ PCMCCY+PLR C+ CG C CCGGKHKAA
Sbjct: 412 FIVPCMCCYVPLRMCHRCGEACGCCGGKHKAA 443
>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
[Homo sapiens]
Length = 410
Score = 272 bits (695), Expect = 5e-73
Identities = 163/422 (38%), Positives = 220/422 (52%), Gaps = 29/422 (6%)
Query: 10 IVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVM--HPEGNGRSG-FLIHGERQKDKLV 66
+VRV+AVVM RDDSSGGW P GGG+S+V VC+V PEG R G ++IHGER +D+
Sbjct: 1 MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60
Query: 67 VLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTS 126
LEC ++ LVY K NP FHHW + + KFGLTFQSPA+A F + + A+ L GS T
Sbjct: 61 TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120
Query: 127 SSTIHNEAELGDDDV----FTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHD 182
SS+ + + D T+ DS S+SS R++ +P S I T+
Sbjct: 121 SSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQE------TPPSAAAAPIITMESASG 174
Query: 183 SYPTDHYHLDQPMPRPYRQV----SFPDDDEEIVRINPREKIWM-TGYEDYRHAPVRGKY 237
PT + + Y + P+ E + W GYEDYR +
Sbjct: 175 FGPTTPPQRRRSSAQSYPPLLPFTGIPEPSEPLAGAGGLG--WGGRGYEDYRRSG----- 227
Query: 238 PDPSEDADSSYVRFAK-GEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRR 296
P + VRFAK G + P + P PS ++
Sbjct: 228 PPAPLALSTCVVRFAKTGALRGAALGPPAALPAPLTEAAPPAPPARPPPGPGPSSAPAKA 287
Query: 297 RKEDGERSRCVYCRDMFNHE-ENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPE 355
E E +RCV+CR +F + R G C +APD R +RR+SC+WCA+S+LYHC+SD E
Sbjct: 288 SPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAE 347
Query: 356 GDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRC--CGGKHKA 413
GD++DPC+C+ + RW AL ALS PC+CCY PLRAC+ C C CGG+H+
Sbjct: 348 GDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEE 407
Query: 414 AA 415
AA
Sbjct: 408 AA 409
>gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b
[Homo sapiens]
Length = 152
Score = 134 bits (338), Expect = 1e-31
Identities = 67/123 (54%), Positives = 85/123 (69%), Gaps = 3/123 (2%)
Query: 10 IVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVM--HPEGNGRSG-FLIHGERQKDKLV 66
+VRV+AVVM RDDSSGGW P GGG+S+V VC+V PEG R G ++IHGER +D+
Sbjct: 1 MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60
Query: 67 VLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTS 126
LEC ++ LVY K NP FHHW + + KFGLTFQSPA+A F + + A+ L GS T
Sbjct: 61 TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120
Query: 127 SST 129
SS+
Sbjct: 121 SSS 123
>gi|27501452 sprouty homolog 3 [Homo sapiens]
Length = 288
Score = 70.5 bits (171), Expect = 3e-12
Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 277 PKGRGGSVIKTQPSRGKSRRR----KEDGERSRCVYCRDMFNHEENRRGHC--------- 323
P G S+I+TQP G + K + E+S +F EE R C
Sbjct: 105 PSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPL 164
Query: 324 -------QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFC-LR 374
Q S + + +C+ C + YHC +D E + D PCSC S C +R
Sbjct: 165 PSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS---CFVR 221
Query: 375 WMALIALSFLAPCMCCYLPLRACYH 399
W A+ +S PC+CCYLP R C H
Sbjct: 222 WAAMSLISLFLPCLCCYLPTRGCLH 246
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 68.2 bits (165), Expect = 1e-11
Identities = 41/115 (35%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 6 SDSYIVRVKAVVMTRDDSSGGWFPQEGG-GISRVGVCKVMHPEGNGRSGFLIHGERQKDK 64
S+ I + +A VM DD++ W P G G SRV + H GN F + G + +D
Sbjct: 2 SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRV---HIYHHTGNNT--FRVVGRKIQDH 56
Query: 65 LVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 119
VV+ C + K L Y +A TFH W+ + +GL F S DA F + A+E L
Sbjct: 57 QVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 111
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 68.2 bits (165), Expect = 1e-11
Identities = 41/115 (35%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 6 SDSYIVRVKAVVMTRDDSSGGWFPQEGG-GISRVGVCKVMHPEGNGRSGFLIHGERQKDK 64
S+ I + +A VM DD++ W P G G SRV + H GN F + G + +D
Sbjct: 2 SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRV---HIYHHTGNNT--FRVVGRKIQDH 56
Query: 65 LVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 119
VV+ C + K L Y +A TFH W+ + +GL F S DA F + A+E L
Sbjct: 57 QVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 111
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 63.2 bits (152), Expect = 4e-10
Identities = 49/183 (26%), Positives = 78/183 (42%), Gaps = 24/183 (13%)
Query: 6 SDSYIVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGERQKD 63
S+ I + +A VM DD+S W P + G G SR+ + + F + G + +D
Sbjct: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIY-----HNTASNTFRVVGVKLQD 58
Query: 64 KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKA--IEDLIE 121
+ VV+ + K L Y +A PTFH W+ + +GL F S +A F + A I + E
Sbjct: 59 QQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQE 118
Query: 122 GSTTSSSTIHN-----EAELGDDDVFTTATDSSSNSSQKRE----------QPTRTISSP 166
G +S + N E ++ V S ++R P+ S+P
Sbjct: 119 GGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAP 178
Query: 167 TSC 169
SC
Sbjct: 179 VSC 181
>gi|5032115 sprouty 2 [Homo sapiens]
Length = 315
Score = 61.6 bits (148), Expect = 1e-09
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 329 SVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFCLRWMALIALSFLAPC 387
S + I +C+ C + YHC +D E + D PCSC S C RW A+ +S PC
Sbjct: 208 SAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSC--SQSHCCTRWSAMGVMSLFLPC 265
Query: 388 MCCYLPLRACYHCGVMCRCC 407
+ CYLP + C +C+ C
Sbjct: 266 LWCYLPAKGCLK---LCQGC 282
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 60.1 bits (144), Expect = 4e-09
Identities = 40/120 (33%), Positives = 59/120 (49%), Gaps = 8/120 (6%)
Query: 6 SDSYIVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGER-QK 62
S++ I +A VM DD + W P G SRV + +P N F + G + Q
Sbjct: 2 SETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYH--NPTANS---FRVVGRKMQP 56
Query: 63 DKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEG 122
D+ VV+ C + + + Y +A P FH W+ + +GL F S DA F G+ A+E L G
Sbjct: 57 DQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGG 116
>gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo
sapiens]
Length = 319
Score = 59.7 bits (143), Expect = 5e-09
Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 329 SVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTD-PCSCDTSDEKFCLRWMALIALSFLAP 386
S + + +CM + YHC +D EGD Y+D PCSC S C R++ + A+S P
Sbjct: 211 SAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSC--SQSHCCSRYLCMGAMSLFLP 268
Query: 387 CMCCYLPLRACYHCGVMCRCC 407
C+ CY P + C +CR C
Sbjct: 269 CLLCYPPAKGCLK---LCRRC 286
>gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo
sapiens]
Length = 319
Score = 59.7 bits (143), Expect = 5e-09
Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 329 SVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTD-PCSCDTSDEKFCLRWMALIALSFLAP 386
S + + +CM + YHC +D EGD Y+D PCSC S C R++ + A+S P
Sbjct: 211 SAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSC--SQSHCCSRYLCMGAMSLFLP 268
Query: 387 CMCCYLPLRACYHCGVMCRCC 407
C+ CY P + C +CR C
Sbjct: 269 CLLCYPPAKGCLK---LCRRC 286
>gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]
Length = 299
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 324 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 381
Q+ S +T + +CM + YHC + D EG D PCSC S+ C RW + AL
Sbjct: 184 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 241
Query: 382 SFLAPCMCCYLPLRAC 397
S + PC+ CYLP C
Sbjct: 242 SVVLPCLLCYLPATGC 257
>gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]
Length = 322
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 324 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 381
Q+ S +T + +CM + YHC + D EG D PCSC S+ C RW + AL
Sbjct: 207 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 264
Query: 382 SFLAPCMCCYLPLRAC 397
S + PC+ CYLP C
Sbjct: 265 SVVLPCLLCYLPATGC 280
>gi|14210518 PAR-6 gamma protein [Homo sapiens]
Length = 376
Score = 39.3 bits (90), Expect = 0.007
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 8/140 (5%)
Query: 93 RKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEA-ELGDDDVFTTATDSSSN 151
R+F L P F + V T + +H + + +DD F A S++
Sbjct: 30 RRFSLDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANP 89
Query: 152 SS----QKREQPTR-TISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMPRPYRQVSFPD 206
QKRE+ R ++ + + C RR LG L D P HLD +PR +R VS
Sbjct: 90 LLRVFIQKREEAERGSLGAGSLCRRRR--ALGALRDEGPRRRAHLDIGLPRDFRPVSSII 147
Query: 207 DDEEIVRINPREKIWMTGYE 226
D + + + R ++ G E
Sbjct: 148 DVDLVPETHRRVRLHRHGCE 167
>gi|7662022 lipin 2 [Homo sapiens]
Length = 896
Score = 32.7 bits (73), Expect = 0.62
Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 26/130 (20%)
Query: 98 TFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELG---DDDVFTTATDSSSNSSQ 154
T +P+ + R +K +D + +S+ + ++G DDD A SSN+S
Sbjct: 145 TIFTPSSVKKKKRRRKKYKQDSKKEEQAASAAAEDTCDVGVSSDDDKGAQAARGSSNASL 204
Query: 155 KREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLD----QPMPRPYRQVSFPDDDEE 210
K E+ C+ ++ G DHY L P+ Y Q + P D E
Sbjct: 205 KEEE----------CKEPLLFHSG--------DHYPLSDGDWSPLETTYPQTACPKSDSE 246
Query: 211 IVRINPREKI 220
+ + P E +
Sbjct: 247 L-EVKPAESL 255
>gi|4757886 pituitary tumor-transforming gene 1 protein-interacting
protein precursor [Homo sapiens]
Length = 180
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 6/88 (6%)
Query: 324 QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS-CDTSDEKFCLRWMALIALS 382
Q+ + C++ VSC+WC + C+ P P S C S ++ + W+ AL
Sbjct: 42 QNTNKTCEECLKNVSCLWCNTNKA--CLDYPVTSVLPPASLCKLSSARWGVCWVNFEALI 99
Query: 383 FLAPCMCCYLPLRACYHCGVMCRCCGGK 410
+ L L C C CC K
Sbjct: 100 ITMSVVGGTLLLGIAICC---CCCCRRK 124
>gi|239750462 PREDICTED: similar to hCG2033802 [Homo sapiens]
Length = 188
Score = 32.0 bits (71), Expect = 1.1
Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 16/104 (15%)
Query: 323 CQDAPDSVRTCIRRVSCMWCADSM--LYHCMSDPEGDYT-------DPCSCDTSDEKFCL 373
C D + T ++ ++C CA + + CM YT D C C + C+
Sbjct: 20 CMDVCVCLYTMLKEITCDVCARACACVCECMDVCMCLYTMLKDVTCDVCMCTCTCMCVCV 79
Query: 374 R-WMALIALSFLAPCMCCYLP-LRACYH-----CGVMCRCCGGK 410
WM + + L C RAC C +C CCGG+
Sbjct: 80 SAWMCVCMYTMLKEVTCDVCARARACVRECMDVCAPVCVCCGGQ 123
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)
Query: 341 WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 397
W AD +HC S P G P SC +E C + + S C C R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 30.8 bits (68), Expect = 2.4
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 236 KYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSR 295
K+ SE + F++ E P + P +S +G G+ +P + S+
Sbjct: 470 KHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAA-GLEPRKLSSK 528
Query: 296 RRKEDGERSRCVYCRDMFNHEENRRGHCQ 324
R+ D E+ C C + FN RR HC+
Sbjct: 529 TRR-DKEKQSCKSCGETFNSITKRRHHCK 556
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 30.8 bits (68), Expect = 2.4
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 236 KYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSR 295
K+ SE + F++ E P + P +S +G G+ +P + S+
Sbjct: 470 KHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAA-GLEPRKLSSK 528
Query: 296 RRKEDGERSRCVYCRDMFNHEENRRGHCQ 324
R+ D E+ C C + FN RR HC+
Sbjct: 529 TRR-DKEKQSCKSCGETFNSITKRRHHCK 556
>gi|148806908 fibronectin type III domain containing 1 [Homo
sapiens]
Length = 1894
Score = 30.4 bits (67), Expect = 3.1
Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 19/85 (22%)
Query: 234 RGKYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGED----------------- 276
RG PS S+ A VP H ++P + S G ED
Sbjct: 839 RGPRLQPSSSPQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSS 898
Query: 277 --PKGRGGSVIKTQPSRGKSRRRKE 299
P RG ++ P RG S RKE
Sbjct: 899 RQPISRGWEDLRRSPQRGASLHRKE 923
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 30.4 bits (67), Expect = 3.1
Identities = 35/155 (22%), Positives = 61/155 (39%), Gaps = 19/155 (12%)
Query: 3 SPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMH-PEGNGRSGF----LIH 57
+P S + + + V R +PQ G +G C + H E G S F L
Sbjct: 61 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEG---LLGECMIRHGKELGGESNFGDALLDA 117
Query: 58 GERQKDKLVV---LECYVRKDLVYTKAN-------PTFHHWK-VDNRKFGLTFQSPADAR 106
GE K V L+ V+++ + N HH K ++ R+ ++ +
Sbjct: 118 GESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGK 177
Query: 107 AFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDV 141
D +R+A+E E + +++HN E + V
Sbjct: 178 IPDEELRQALEKFEESKEVAETSMHNLLETDIEQV 212
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 30.0 bits (66), Expect = 4.0
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 121 EGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGH 179
+ S +SSS+ + +E D + ++DSSS SS + E + +ISS +S + GH
Sbjct: 665 KSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSE-ESDSSSISSHSSASANDVRKKGH 722
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,709,601
Number of Sequences: 37866
Number of extensions: 953209
Number of successful extensions: 2659
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2586
Number of HSP's gapped (non-prelim): 81
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.