Search of human proteins with 189217847

Search of human proteins with 189217847

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189217847 spastic paraplegia 21 isoform b [Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189217847 spastic paraplegia 21 isoform b [Homo sapiens]           571   e-163
gi|189217845 spastic paraplegia 21 isoform a [Homo sapiens]           556   e-159
gi|7706174 spastic paraplegia 21 isoform a [Homo sapiens]             556   e-159
gi|49355818 plexin A1 [Homo sapiens]                                   30   3.1  
gi|32698730 nuclear fragile X mental retardation protein interac...    30   3.1  
gi|94721313 mesoderm induction early response 1, family member 3...    29   4.0  
gi|113722116 plexin A2 [Homo sapiens]                                  29   5.3  
gi|150010540 FERM domain containing 4B [Homo sapiens]                  29   5.3  
gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]         28   9.0  

>gi|189217847 spastic paraplegia 21 isoform b [Homo sapiens]
          Length = 281

 Score =  571 bits (1472), Expect = e-163
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIAVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTW 120
           RQILALTGWGYRVIAVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTW
Sbjct: 61  RQILALTGWGYRVIAVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTW 120

Query: 121 TANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNS 180
           TANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNS
Sbjct: 121 TANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNS 180

Query: 181 YVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNL 240
           YVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNL
Sbjct: 181 YVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNL 240

Query: 241 YVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ 281
           YVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ
Sbjct: 241 YVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ 281


>gi|189217845 spastic paraplegia 21 isoform a [Homo sapiens]
          Length = 308

 Score =  556 bits (1434), Expect = e-159
 Identities = 281/308 (91%), Positives = 281/308 (91%), Gaps = 27/308 (8%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIA---------------------------VHLFGASLGGFLAQKFAE 93
           RQILALTGWGYRVIA                           VHLFGASLGGFLAQKFAE
Sbjct: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120

Query: 94  YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 153
           YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA
Sbjct: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180

Query: 154 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 213
           IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK
Sbjct: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240

Query: 214 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 273
           LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS
Sbjct: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300

Query: 274 LGISQEEQ 281
           LGISQEEQ
Sbjct: 301 LGISQEEQ 308


>gi|7706174 spastic paraplegia 21 isoform a [Homo sapiens]
          Length = 308

 Score =  556 bits (1434), Expect = e-159
 Identities = 281/308 (91%), Positives = 281/308 (91%), Gaps = 27/308 (8%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIA---------------------------VHLFGASLGGFLAQKFAE 93
           RQILALTGWGYRVIA                           VHLFGASLGGFLAQKFAE
Sbjct: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120

Query: 94  YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 153
           YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA
Sbjct: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180

Query: 154 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 213
           IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK
Sbjct: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240

Query: 214 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 273
           LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS
Sbjct: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300

Query: 274 LGISQEEQ 281
           LGISQEEQ
Sbjct: 301 LGISQEEQ 308


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 129  PAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIR 188
            P FML   +      GP+D +  +A  + +   + + Q      LTLNC N   E     
Sbjct: 1437 PLFMLYCAIKQQMEKGPIDAITGEA-RYSLSEDKLIRQQIDYKTLTLNCVNP--ENENAP 1493

Query: 189  DIPVTIMDVFDQSALSTEAKEEMYKLYPNARR 220
            ++PV  +D    +    +  +  YK  P ++R
Sbjct: 1494 EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQR 1525


>gi|32698730 nuclear fragile X mental retardation protein
           interacting protein 2 [Homo sapiens]
          Length = 695

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 88  AQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWL--MPAFMLKKIVLGNFSSGP 145
           A K  E  +K+ +  S+   +S S +S   +T T +S  L  +P   LK +   NFS+GP
Sbjct: 359 ASKVKENLNKTIQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGP 418

Query: 146 V 146
           V
Sbjct: 419 V 419


>gi|94721313 mesoderm induction early response 1, family member 3
           [Homo sapiens]
          Length = 549

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 6/57 (10%)

Query: 148 PMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALS 204
           P + D +D +VD  E+LG +  AS LT N       P  I D  + I++ F  S L+
Sbjct: 347 PGVTDYMDRLVDETEALGGTVNASALTSN------RPEPIPDQQLNILNSFTASDLT 397


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 129  PAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIR 188
            P FML   +      GP+D +  +A  + +   + + Q      L LNC N   +     
Sbjct: 1457 PLFMLYCAIKQQMEKGPIDAITGEA-RYSLSEDKLIRQQIEYKTLILNCVNP--DNENSP 1513

Query: 189  DIPVTIMDVFDQSALSTEAKEEMYKLYPNARR 220
            +IPV +++    + +  +  + +YK  P ++R
Sbjct: 1514 EIPVKVLNCDTITQVKEKILDAVYKNVPYSQR 1545


>gi|150010540 FERM domain containing 4B [Homo sapiens]
          Length = 1034

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 86  FLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTAN-----SFWLMPAFMLKKIVLGN 140
           F  +KFA   H   R+   +   +F  + +F QTW AN     S W+M A    +  L  
Sbjct: 304 FREKKFAVEVHDPRRIS--VSRRTFGQSGLFVQTWYANSSLIKSIWVM-AISQHQFYLDR 360

Query: 141 FSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYV 182
             S    P  A ++D +   L   G    +  +TL  ++ ++
Sbjct: 361 KQSKAKIP-SARSLDEIAMDLTETGTQRASKLVTLEAKSQFI 401


>gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]
          Length = 488

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 13/40 (32%)

Query: 11  NWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLP 50
           NW  GT PL           +W  Y A PR + C L+F+P
Sbjct: 254 NW--GTSPL-----------LWYFYSALPRGLGCSLLFIP 280


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,326,539
Number of Sequences: 37866
Number of extensions: 407242
Number of successful extensions: 722
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 717
Number of HSP's gapped (non-prelim): 9
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.