Guide to the Human Genome
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Search of human proteins with 187960073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187960073 MAD2 homolog [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187960079 MAD2 homolog [Homo sapiens]                              426   e-120
gi|187960073 MAD2 homolog [Homo sapiens]                              426   e-120
gi|4505067 MAD2-like 1 [Homo sapiens]                                  55   4e-08
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom...    38   0.005
gi|188497683 FAST kinase domains 1 [Homo sapiens]                      30   2.0  
gi|122937476 lipase, family member K [Homo sapiens]                    30   2.0  
gi|19549331 cytoglobin [Homo sapiens]                                  28   4.4  
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]                28   4.4  
gi|164420681 methionyl aminopeptidase 1 [Homo sapiens]                 28   4.4  
gi|169167993 PREDICTED: hypothetical protein [Homo sapiens]            28   5.7  
gi|169167430 PREDICTED: hypothetical protein [Homo sapiens]            28   5.7  
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho...    28   5.7  
gi|4502769 CCAAT/enhancer binding protein gamma [Homo sapiens]         28   7.4  

>gi|187960079 MAD2 homolog [Homo sapiens]
          Length = 211

 Score =  426 bits (1095), Expect = e-120
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL 60
           MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL
Sbjct: 1   MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL 60

Query: 61  NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE 120
           NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE
Sbjct: 61  NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE 120

Query: 121 QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH 180
           QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH
Sbjct: 121 QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH 180

Query: 181 MHDPRLIPLKTMTSDILKMQLYVEERAHKGS 211
           MHDPRLIPLKTMTSDILKMQLYVEERAHKGS
Sbjct: 181 MHDPRLIPLKTMTSDILKMQLYVEERAHKGS 211


>gi|187960073 MAD2 homolog [Homo sapiens]
          Length = 211

 Score =  426 bits (1095), Expect = e-120
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL 60
           MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL
Sbjct: 1   MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPEL 60

Query: 61  NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE 120
           NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE
Sbjct: 61  NQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPPLLSISSDSLLSHVE 120

Query: 121 QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH 180
           QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH
Sbjct: 121 QLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVH 180

Query: 181 MHDPRLIPLKTMTSDILKMQLYVEERAHKGS 211
           MHDPRLIPLKTMTSDILKMQLYVEERAHKGS
Sbjct: 181 MHDPRLIPLKTMTSDILKMQLYVEERAHKGS 211


>gi|4505067 MAD2-like 1 [Homo sapiens]
          Length = 205

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 4/141 (2%)

Query: 16  ADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLL 75
           A+++ EF    ++ ILY R +YP   F + +KY + + ++   EL +Y+ + +  +K  L
Sbjct: 17  AEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWL 76

Query: 76  EKNDVEKVVVVILDKEHRPV-EKFVFEITQPPLL---SISSDSLLSHVEQLLRAFILKIS 131
            K  V+K+VVVI + E   V E++ F+I         S   +     ++  +R+ I +I+
Sbjct: 77  YKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQIT 136

Query: 132 VCDAVLDHNPPGCTFTVLVHT 152
                L      C+F +L++T
Sbjct: 137 ATVTFLPLLEVSCSFDLLIYT 157


>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
           sapiens]
          Length = 802

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 14/107 (13%)

Query: 106 PLLSISSDSLLSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQV 165
           P +  +S+  L  +EQ L A +L+ SVCD VLDH P      +   T +A      +  +
Sbjct: 425 PEVKSTSERFLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLL 484

Query: 166 IKD--FPWILA--DEQDVHMHDP----------RLIPLKTMTSDILK 198
           +++  FP ILA  +E  V    P          R+  LK +  +ILK
Sbjct: 485 LENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILK 531


>gi|188497683 FAST kinase domains 1 [Homo sapiens]
          Length = 847

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 6/72 (8%)

Query: 135 AVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTS 194
           A+L     GC F +L   ++  T  ++  + ++D P  L       +H+      K M  
Sbjct: 61  AILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLT------LHNLATNKFKLMND 114

Query: 195 DILKMQLYVEER 206
           D L   LYV ++
Sbjct: 115 DTLVNVLYVTQQ 126


>gi|122937476 lipase, family member K [Homo sapiens]
          Length = 399

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 128 LKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMH 182
           L +S  D  L HNP G +   ++H  +A          ++ F W  +D+  +H H
Sbjct: 270 LNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQ-----LQAFDWGNSDQNMMHFH 319


>gi|19549331 cytoglobin [Homo sapiens]
          Length = 190

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 20  CEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEK-N 78
           CE + VA+ +  +V        F + K    P++M   P+L ++    +  +  ++E  +
Sbjct: 38  CEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLH 97

Query: 79  DVEKV--VVVILDKEH---RPVEKFVFEITQPPLLSISSDSLLS 117
           D +KV  V+ ++ K H     VE   F+I    +L + ++   S
Sbjct: 98  DPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEEFAS 141


>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
          Length = 2073

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 16/72 (22%)

Query: 74   LLEKNDVEKVVVVILDK----------------EHRPVEKFVFEITQPPLLSISSDSLLS 117
            LLE N   +V + +LD                  H P+ K VF+I    L +  S+  L 
Sbjct: 1395 LLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLK 1454

Query: 118  HVEQLLRAFILK 129
            HV   LRAFI K
Sbjct: 1455 HVFASLRAFISK 1466


>gi|164420681 methionyl aminopeptidase 1 [Homo sapiens]
          Length = 386

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 8   DLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDT 67
           D+  G +   V  E ++ AVHL    R  YP  +      YN P   SC   +N+ I   
Sbjct: 151 DVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPL----NYYNFP--KSCCTSVNEVICHG 204

Query: 68  LHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVF 100
           +   +PL E + V   + +  +  H  + +  F
Sbjct: 205 IPDRRPLQEGDIVNVDITLYRNGYHGDLNETFF 237


>gi|169167993 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 136 VLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSD 195
           +L     GCTF +L   ++      +KI ++K+  ++    Q + +H+      K M  +
Sbjct: 102 ILSEKQVGCTFNILWKLQK------QKISLLKNVEYVRDHSQFLTLHNLATNKFKLMNGN 155

Query: 196 ILKMQLYVEER 206
            L   LY+ ++
Sbjct: 156 TLVNVLYITQQ 166


>gi|169167430 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 136 VLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSD 195
           +L     GCTF +L   ++      +KI ++K+  ++    Q + +H+      K M  +
Sbjct: 102 ILSEKQVGCTFNILWKLQK------QKISLLKNVEYVRDHSQFLTLHNLATNKFKLMNGN 155

Query: 196 ILKMQLYVEER 206
            L   LY+ ++
Sbjct: 156 TLVNVLYITQQ 166


>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
            sapiens]
          Length = 3526

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 146  FTVLVHTREAATRNMEKIQVIKDFPWILA--DEQDVHMHDPR 185
            F  L+H    A R+   +     FPWILA  D ++V + +P+
Sbjct: 2706 FQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPK 2747


>gi|4502769 CCAAT/enhancer binding protein gamma [Homo sapiens]
          Length = 150

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 43  QKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEI 102
           Q+R++ N+ V+ S   +  Q  QDTL  V  L E+N+  +  + +L KE           
Sbjct: 67  QRRERNNMAVKKS-RLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKE----------- 114

Query: 103 TQPPLLSISSDSLLSHVEQL 122
                LS+  D  L H   L
Sbjct: 115 -----LSVLKDLFLEHAHNL 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,839,119
Number of Sequences: 37866
Number of extensions: 322970
Number of successful extensions: 718
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 710
Number of HSP's gapped (non-prelim): 13
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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