BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|187423910 solute carrier family 7, member 9 [Homo sapiens] (487 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 964 0.0 gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 964 0.0 gi|7657683 solute carrier family 7, (cationic amino acid transpo... 419 e-117 gi|71979932 solute carrier family 7 (cationic amino acid transpo... 415 e-116 gi|115648063 solute carrier family 7 (cationic amino acid transp... 411 e-115 gi|115648022 solute carrier family 7 (cationic amino acid transp... 411 e-115 gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 410 e-114 gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 410 e-114 gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 410 e-114 gi|33286428 solute carrier family 7 (cationic amino acid transpo... 387 e-107 gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 369 e-102 gi|71999149 solute carrier family 7, (cationic amino acid transp... 254 1e-67 gi|33286430 solute carrier family 7 (cationic amino acid transpo... 222 7e-58 gi|110347453 solute carrier family 7 (cationic amino acid transp... 125 7e-29 gi|114326550 solute carrier family 7 (cationic amino acid transp... 103 5e-22 gi|114326544 solute carrier family 7 (cationic amino acid transp... 103 5e-22 gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 102 1e-21 gi|4507047 solute carrier family 7 (cationic amino acid transpor... 100 2e-21 gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 100 4e-21 gi|181337167 solute carrier family 7 (cationic amino acid transp... 86 8e-17 gi|198041678 solute carrier family 12 (potassium-chloride transp... 39 0.011 gi|11968148 solute carrier family 12 (potassium-chloride transpo... 39 0.011 gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 35 0.15 gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 35 0.15 gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 35 0.15 gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 35 0.15 gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 35 0.15 gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 35 0.15 gi|41327726 nicotinic acetylcholine receptor beta 1 subunit prec... 33 0.45 gi|31881740 solute carrier family 12 (potassium/chloride transpo... 33 0.45 >gi|187423910 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 964 bits (2491), Expect = 0.0 Identities = 487/487 (100%), Positives = 487/487 (100%) Query: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE Sbjct: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60 Query: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI Sbjct: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120 Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180 Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240 Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300 Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360 Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420 Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480 Query: 481 PPEEDPE 487 PPEEDPE Sbjct: 481 PPEEDPE 487 >gi|7657591 solute carrier family 7, member 9 [Homo sapiens] Length = 487 Score = 964 bits (2491), Expect = 0.0 Identities = 487/487 (100%), Positives = 487/487 (100%) Query: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE Sbjct: 1 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE 60 Query: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI Sbjct: 61 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI 120 Query: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF Sbjct: 121 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF 180 Query: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY Sbjct: 181 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240 Query: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP 300 Query: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI Sbjct: 301 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI 360 Query: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI Sbjct: 361 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI 420 Query: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV Sbjct: 421 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV 480 Query: 481 PPEEDPE 487 PPEEDPE Sbjct: 481 PPEEDPE 487 >gi|7657683 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 [Homo sapiens] Length = 501 Score = 419 bits (1076), Expect = e-117 Identities = 210/475 (44%), Positives = 312/475 (65%), Gaps = 6/475 (1%) Query: 15 SIQSQEP---KTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAA 71 S+ ++EP + L++++ L+ G+SII+GTIIG+GIF+SPK VL NT +VG L IW Sbjct: 26 SLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTV 85 Query: 72 CGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLS 131 CGVL+ GAL +AELGT I KSGG Y Y++E +GP+PA++ W L++I+P + A+I L+ Sbjct: 86 CGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLA 145 Query: 132 FSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAII 191 F Y+ PF++ C+ P++ +K + A I + +NS+SV + +Q T KL + II Sbjct: 146 FGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILII 205 Query: 192 IISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRN 251 I+ G++ L +G T+NF ++F G S+ + LAFY G++AY GW LN++TEE+ NP + Sbjct: 206 IVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265 Query: 252 LPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAF 311 +PLAI I + +VT Y+L NV+YFT + A ELL S AVAVTF +R+L S VP+FVA Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325 Query: 312 STIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDI 371 S G+ NG F RL YVA REGH+ ++LS I VR+ TP PA+I + I + GD+ Sbjct: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385 Query: 372 NSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIIS 431 +SL+N+ SFA WLF GL + GLI +R+ ++ RP KVP+ IP L + +F+V + S Sbjct: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445 Query: 432 KPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEE 484 P + V+ L+G+ Y+LF+ + K W + +S+ IT LQ+++EVVP E+ Sbjct: 446 DPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499 >gi|71979932 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [Homo sapiens] Length = 507 Score = 415 bits (1066), Expect = e-116 Identities = 214/473 (45%), Positives = 306/473 (64%), Gaps = 5/473 (1%) Query: 15 SIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGV 74 S + E + +LQ+ + L++G++IIVGTIIGSGIFV+P VL + G L++WAACGV Sbjct: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94 Query: 75 LATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSE 134 + +GALC+AELGT I+KSGG+Y Y++E YG +PA+L W L++I+P+S I+ L F+ Sbjct: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154 Query: 135 YVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIIS 194 Y+ P + C P+ K +A +L ++ VN SV+ + VQ+ F AAKL+ +A+II+ Sbjct: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214 Query: 195 GLVLLAQGNTKNFDN--SFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNL 252 G V + +G+ N D SFEG +L VG I LA Y+GL+AY GWN LN++TEE+ NPYRNL Sbjct: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274 Query: 253 PLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFS 312 PLAIII +P+VT Y+L N++YFT ++ ++L S+AVAV FG+ L SWI+P+FV S Sbjct: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334 Query: 313 TIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDIN 372 G+ NG+ FT+ RL +V REGH+ +LS I + LTP P+++F ++ +Y DI Sbjct: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394 Query: 373 SLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISK 432 S++N+FSF WL L I+G+I +R + ELERPIKV + +PV L +FL+ Sbjct: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454 Query: 433 PTWEYLYCVLFILSGLLFYFLFVHYKF--GWAQKISKPITMHLQMLMEVVPPE 483 P E ILSGL YF V +K W + T+ Q LM+VVP E Sbjct: 455 PV-ECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506 >gi|115648063 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 411 bits (1057), Expect = e-115 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%) Query: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62 +T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + Sbjct: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77 Query: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122 G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P Sbjct: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137 Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182 T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197 Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242 AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257 Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302 EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317 Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362 W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377 Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422 IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437 Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456 FLV+ P+ + T L + LSG+ FYF+ V+ Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470 >gi|115648022 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 [Homo sapiens] Length = 515 Score = 411 bits (1057), Expect = e-115 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%) Query: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62 +T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + Sbjct: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77 Query: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122 G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P Sbjct: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137 Query: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182 T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT Sbjct: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197 Query: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242 AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T Sbjct: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257 Query: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302 EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S Sbjct: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317 Query: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362 W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A Sbjct: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377 Query: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422 IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV Sbjct: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437 Query: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456 FLV+ P+ + T L + LSG+ FYF+ V+ Sbjct: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470 >gi|186910308 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 410 bits (1053), Expect = e-114 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%) Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77 S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ + Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84 Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137 GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+ Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144 Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197 P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204 Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257 L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317 I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377 N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384 Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437 +SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443 Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 L + LSGL FYFL + H + + ++I T +LQ+L V E D E Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497 >gi|186910306 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 410 bits (1053), Expect = e-114 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%) Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77 S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ + Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84 Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137 GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+ Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144 Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197 P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204 Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257 L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317 I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377 N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384 Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437 +SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443 Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 L + LSGL FYFL + H + + ++I T +LQ+L V E D E Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497 >gi|186910304 solute carrier family 7 member 7 [Homo sapiens] Length = 511 Score = 410 bits (1053), Expect = e-114 Identities = 208/474 (43%), Positives = 307/474 (64%), Gaps = 5/474 (1%) Query: 18 SQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT 77 S P+ L+KE+ L++G+ +IVG +IGSGIFVSPK VL + + G L+IWA G+ + Sbjct: 25 SPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSV 84 Query: 78 LGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVC 137 GALC+AELGT I KSG Y Y++EA+G A++ W SL++I+PTS AII ++F+ Y+ Sbjct: 85 FGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMV 144 Query: 138 APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197 P + C P + LAAA I ++ +N V+ G+ VQ+IFT AK++ + +I++G+V Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204 Query: 198 LLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAII 257 L QG + +F+NSFEG+ +VG I+LA Y+ L++Y GW+ LNY+TEE++NP RNLPL+I Sbjct: 205 RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIG 264 Query: 258 IGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAA 317 I +P+VT YIL NV+Y+TV+ ++L S AVAVTF D++ +WI+PL VA S G Sbjct: 265 ISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGL 324 Query: 318 NGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNY 377 N + A RL +V REGH+ + I V R TP P+++F GI+A IY+ DI L+NY Sbjct: 325 NASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINY 384 Query: 378 FSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEY 437 +SF+ W F GL+I+G + +R+ + RP+K+ V P++ L ++FLV P+ S T Sbjct: 385 YSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYS-DTINS 443 Query: 438 LYCVLFILSGLLFYFLFV----HYKFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 L + LSGL FYFL + H + + ++I T +LQ+L V E D E Sbjct: 444 LIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLE 497 >gi|33286428 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform a [Homo sapiens] Length = 535 Score = 387 bits (993), Expect = e-107 Identities = 199/440 (45%), Positives = 292/440 (66%), Gaps = 10/440 (2%) Query: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84 +L+KE+GL+S IIVG IIGSGIFVSPK VL N +VG LI+W G + +GALC+A Sbjct: 35 ALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYA 94 Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144 ELG I KSGG+Y Y+ + +G + +L W +++VI PT+ A+I L+FS YV P + C Sbjct: 95 ELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTC 154 Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204 PP+ ++ LAA +L ++ VN SVR + VQ+IFTA KL+ +A+III G+V + +G Sbjct: 155 FPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEY 214 Query: 205 KNFD--NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261 + N+FE Q +G ++LAF G +AY GWN LNY+TEEL +PY+NLP AI I IP Sbjct: 215 FWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIP 274 Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321 LVT Y+ NV+Y T M+ ELL S AVAVTFG+++L +WI+P+ VA ST G NG+ Sbjct: 275 LVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL 334 Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381 FT+ RL + REGH+ VL+ I V+R TP PA++F I + ++ D+ +L+NY F Sbjct: 335 FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFI 394 Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440 +LFYG+T+ G IV+R+ + ++ RPIK+ ++ P++ L FL++ + S+P + C Sbjct: 395 NYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCG 450 Query: 441 --VLFILSGLLFYFLFVHYK 458 + +L+G+ YFL V+++ Sbjct: 451 IGLAIMLTGVPVYFLGVYWQ 470 >gi|9790235 solute carrier family 7, member 10 [Homo sapiens] Length = 523 Score = 369 bits (946), Expect = e-102 Identities = 199/471 (42%), Positives = 300/471 (63%), Gaps = 12/471 (2%) Query: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84 +L+KE+GL+S +II+G IIGSGIF+SPK VL ++ +VG L +W G + LG+LC+A Sbjct: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94 Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144 ELG I KSGG+Y Y+ E +G + +L W++++++ PTS A+I ++FS YV P + C Sbjct: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154 Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204 PP + L+ A ++ ++ VNS SVR + +Q++FT KL+ +++II GL+ + QG+ Sbjct: 155 IPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHF 214 Query: 205 KNF--DNSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261 + N+F SVG ++LAF G +A+ GWN LNY+TEE+ + +NLP AI I IP Sbjct: 215 EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIP 274 Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321 LVT Y N++YFT M+ ELL S AVAVTFG+++L SW++P+ VA ST G NG Sbjct: 275 LVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYL 334 Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381 FT RL + REGH+ +L+ I VR TP PA++ + ++ GD +L+NY SF Sbjct: 335 FTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI 394 Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440 +L YG+TILGL+++R+ R L RPIKV ++IPV + FL++ IS+P + C Sbjct: 395 NYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP----MVCG 450 Query: 441 --VLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEEDPE 487 V+ IL+G+ +FL V + K ++++ +T Q L VV P++ PE Sbjct: 451 VGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPE 501 >gi|71999149 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 [Homo sapiens] Length = 470 Score = 254 bits (649), Expect = 1e-67 Identities = 151/468 (32%), Positives = 246/468 (52%), Gaps = 12/468 (2%) Query: 26 LQKELGLISGISIIVGTIIGSGIFVSPKSVLS-NTEAVGPCLIIWAACGVLATLGALCFA 84 L++ G G S ++ IIG+GIFVSPK VL+ + VG L +WA C +LA LC A Sbjct: 9 LKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSA 68 Query: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144 E+ SG +Y +L +G A+L W SL + A L +EY PF+ C Sbjct: 69 EISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGV-VAGQALLLAEYSIQPFFPSC 127 Query: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQG-- 202 P++ KCLA A + + + S V+ +++Q + K+ I++ I ++G+V L +G Sbjct: 128 SVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKK 187 Query: 203 -NTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261 N + F N+F+ + + A + G +AY G I EL+ P +P I +P Sbjct: 188 ENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALP 247 Query: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321 LVT Y+L+N+SY TV+T E+L S AVA+T+ DR +WI+P ++ S + Sbjct: 248 LVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISI 307 Query: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381 F + R IY+A +EG + + + ++ +P A++ + ++ II + L+NY F Sbjct: 308 FKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFT 366 Query: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCV 441 L+ L ++G++ R+ L P KV + P+ +I V LV+ P++ P Y+Y + Sbjct: 367 GSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVL 426 Query: 442 LFILSGLLFYFLFVHYK--FGWAQKISKPITMHLQMLMEVVPPEEDPE 487 L +LSGLLFY +H+K W +K +T +LQ+L + P+ E Sbjct: 427 LLVLSGLLFYIPLIHFKIRLAWFEK----MTCYLQLLFNICLPDVSEE 470 >gi|33286430 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform b [Homo sapiens] Length = 332 Score = 222 bits (565), Expect = 7e-58 Identities = 112/254 (44%), Positives = 168/254 (66%), Gaps = 8/254 (3%) Query: 209 NSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACY 267 N+FE Q +G ++LAF G +AY GWN LNY+TEEL +PY+NLP AI I IPLVT Y Sbjct: 18 NAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY 77 Query: 268 ILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRL 327 + NV+Y T M+ ELL S AVAVTFG+++L +WI+P+ VA ST G NG+ FT+ RL Sbjct: 78 VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRL 137 Query: 328 IYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYG 387 + REGH+ VL+ I V+R TP PA++F I + ++ D+ +L+NY F +LFYG Sbjct: 138 FFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYG 197 Query: 388 LTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC---VLFI 444 +T+ G IV+R+ + ++ RPIK+ ++ P++ L FL++ + S+P + C + + Sbjct: 198 VTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP----VVCGIGLAIM 253 Query: 445 LSGLLFYFLFVHYK 458 L+G+ YFL V+++ Sbjct: 254 LTGVPVYFLGVYWQ 267 >gi|110347453 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [Homo sapiens] Length = 635 Score = 125 bits (315), Expect = 7e-29 Identities = 99/395 (25%), Positives = 182/395 (46%), Gaps = 27/395 (6%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82 TSL++ L + + VG ++GSG++V +V E GP +++ + V + L ALC Sbjct: 31 TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAK--EVAGPAVLLSFGVAAVASLLAALC 88 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPF-- 140 +AE G + ++G Y + + G + A+L W ++++ A + ++S Y+ + F Sbjct: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGYLDSMFSH 147 Query: 141 --------YVGCKPPQIV---VKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVA 189 +VG ++ LAA IL S S R+ S++ + F+A L+++ Sbjct: 148 SIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVIL 207 Query: 190 IIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPY 249 I+I G +L N + F A + + +A+ G++ + +EE +NP Sbjct: 208 FIVILGFILAQPHNWSADEGGF--APFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPR 265 Query: 250 RNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFV 309 R++PLAI I + + YIL++ ++ L A+A F R A +IV Sbjct: 266 RSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV---- 321 Query: 310 AFSTIGAAN----GTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIY 365 A +I A N F+ R++Y +G +V +++ R P + +G++ Sbjct: 322 AAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFL 381 Query: 366 IIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTR 400 + D+ SLV + S L Y +IV+RF + Sbjct: 382 ALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416 >gi|114326550 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 103 bits (256), Expect = 5e-22 Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82 T L + L + +++ VG+ +G+G++V V + GP ++I L++ L LC Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140 +AE G + +SG Y Y G + A+ W ++ VI S A S + + Sbjct: 84 YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143 Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190 + P ++ + A +L ++ + +L + V +FT L+++ Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203 Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228 ++ISG V +G+ N+ + E +L++ ++ + G Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260 Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288 +A+ G++ + EE +NP R++P+ I+I + + Y ++ + +M +L Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320 Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348 + F PA ++V + + + G+ F R+IY +G + +VL+ I Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380 Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401 TP A + GIIA + LV+ S L Y L + ++++R+ T + Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440 Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449 E+E + +TL +F L I + + + +Y +L+ LL Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488 >gi|114326544 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Homo sapiens] Length = 619 Score = 103 bits (256), Expect = 5e-22 Identities = 100/468 (21%), Positives = 199/468 (42%), Gaps = 47/468 (10%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82 T L + L + +++ VG+ +G+G++V V + GP ++I L++ L LC Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DKAGPSIVICFLVAALSSVLAGLC 83 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAIICLSFSEYVCAPF 140 +AE G + +SG Y Y G + A+ W ++ VI S A S + + Sbjct: 84 YAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNH 143 Query: 141 Y-------VGCKPPQIVVKC---LAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190 + P ++ + A +L ++ + +L + V +FT L+++ Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203 Query: 191 IIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNG---------------------- 228 ++ISG V +G+ N+ + E +L++ ++ + G Sbjct: 204 VMISGFV---KGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATC 260 Query: 229 LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQA 288 +A+ G++ + EE +NP R++P+ I+I + + Y ++ + +M +L Sbjct: 261 FYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESP 320 Query: 289 VAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRR 348 + F PA ++V + + + G+ F R+IY +G + +VL+ I Sbjct: 321 LPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGT 380 Query: 349 LTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF-------TRK 401 TP A + GIIA + LV+ S L Y L + ++++R+ T + Sbjct: 381 RTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGE 440 Query: 402 ELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLL 449 E+E + +TL +F L I + + + +Y +L+ LL Sbjct: 441 EVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLL 488 >gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo sapiens] Length = 658 Score = 102 bits (253), Expect = 1e-21 Identities = 94/416 (22%), Positives = 183/416 (43%), Gaps = 50/416 (12%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82 T L + L + I++ VG+ +G+G++V V GP +++ LA++ A LC Sbjct: 28 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 85 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131 +AE G + K+G Y Y G + A++ W ++ VI +S A ++ Sbjct: 86 YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 145 Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187 +++ F Y G + P CL IL ++ + S V+ ++V +FTA +++ Sbjct: 146 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 201 Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228 + ++++G V +GN N+ S E + +S A NG Sbjct: 202 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 258 Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282 +A+ G++ + EE+RNP + +P+ I+ + + Y ++ + +M Sbjct: 259 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 318 Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342 L + + V F PA ++V + + G+ F R+IY +G + K L+ Sbjct: 319 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLA 378 Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398 I+ + TP A + G +A + D+ +LV+ S + Y L ++++R+ Sbjct: 379 QINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 434 >gi|4507047 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 [Homo sapiens] Length = 629 Score = 100 bits (250), Expect = 2e-21 Identities = 91/412 (22%), Positives = 181/412 (43%), Gaps = 42/412 (10%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLAT-LGALC 82 T L + L +++ VG+ +G+G++V +V E GP ++I LA+ L LC Sbjct: 26 TRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLC 83 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFAII-CLSFSEYVCAP 139 + E G + K+G Y Y G + A++ W ++ +I +S A +F E + P Sbjct: 84 YGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRP 143 Query: 140 F------YVGCKPPQIVVK---CLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAI 190 ++ P ++ + A IL ++ + +L V+ + V IFT ++++ Sbjct: 144 IGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGF 203 Query: 191 IIISGLVLLAQGNTKNF----------------DNSFEGAQLSVGAISLAFYNGL----- 229 I++SG V +G+ KN+ +N + + VG ++G+ Sbjct: 204 IMVSGFV---KGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAA 260 Query: 230 ---WAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQS 286 +A+ G++ + EE++NP + +P+ I+ + + Y ++ + +M L + Sbjct: 261 TCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNN 320 Query: 287 QAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISV 346 + F A + V + + + G+ F R+IY +G + K L+ ++ Sbjct: 321 SPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVND 380 Query: 347 RRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398 R TP A + G +A + D+ LV+ S L Y L ++V+R+ Sbjct: 381 RTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY 432 >gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo sapiens] Length = 697 Score = 100 bits (248), Expect = 4e-21 Identities = 92/416 (22%), Positives = 186/416 (44%), Gaps = 51/416 (12%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGA-LC 82 T L + L + I++ VG+ +G+G++V V GP +++ LA++ A LC Sbjct: 68 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADS--GPSIVVSFLIAALASVMAGLC 125 Query: 83 FAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI--VIKPTSFA---------IICLS 131 +AE G + K+G Y Y G + A++ W ++ VI +S A ++ Sbjct: 126 YAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQ 185 Query: 132 FSEYVCAPF---YVG-CKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187 +++ F Y G + P CL IL ++ + S V+ ++V +FTA +++ Sbjct: 186 IGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNILV 241 Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQ-LSVGAISLAFYNG------------------ 228 + ++++G V +GN N+ S E + +S A NG Sbjct: 242 LLFVMVAGFV---KGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTL 298 Query: 229 ------LWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE 282 +A+ G++ + EE+RNP + +P+ I+ + + Y ++ + +M Sbjct: 299 AGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYL 358 Query: 283 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS 342 L + + V F PA ++V + + G+ F R+++ R+G + + L+ Sbjct: 359 LDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLA 418 Query: 343 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398 +S +R +P A + G+I+ + D+ +LV+ S + Y L ++++R+ Sbjct: 419 RVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRY 473 >gi|181337167 solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 [Homo sapiens] Length = 771 Score = 85.9 bits (211), Expect = 8e-17 Identities = 85/399 (21%), Positives = 166/399 (41%), Gaps = 38/399 (9%) Query: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82 T L + L + IS+ VG+ +G+G++V S L E GP +I+ + V + L +C Sbjct: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVV--SGLVAKEMAGPGVIVSFIIAAVASILSGVC 104 Query: 83 FAELGTMITKS-GGEYPYLMEAYGPIPAYLFSWASLI------VIKPTSFAIICLSFSEY 135 +AE G + K+ G Y Y G A+ W ++ ++ + + S + + Sbjct: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164 Query: 136 VCAPFYVGC--------KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187 + + K + LA + ++ + +L V+ N+ L + Sbjct: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224 Query: 188 VAIIIISGLVLLAQGNTKNFDNSFEGAQLSVG--AISLAFYNGLWAYDGWNQLNYITEEL 245 I+I+GL + N EG L G + +A+ G++ + EE Sbjct: 225 WVFIMIAGLFFI------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEA 278 Query: 246 RNPYRNLPLAIIIGIPLVTACYILMNV------SYFTVMTATELLQSQAVAVTFGDRVLY 299 +NP ++P AI + + Y+ ++V Y+T+ T + L++ F Y Sbjct: 279 KNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEM------FVAHGFY 332 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYG 359 A ++V + + G+ F R+IY +G + + L+++S TP A I G Sbjct: 333 AAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSG 392 Query: 360 IIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398 +A + + + L+ S L Y L + ++++R+ Sbjct: 393 FLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 431 >gi|198041678 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 1 [Homo sapiens] Length = 1139 Score = 38.9 bits (89), Expect = 0.011 Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +LR+ +++P I+ I +A YI V + + L AV G+ V+ + Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 504 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ R+G L+V + P A++ Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 563 Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417 I I I+ ++ + S + Y L V R RP + Sbjct: 564 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 623 Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453 +S+ L L I S W Y V +++GL++ ++ Sbjct: 624 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 655 >gi|11968148 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 2 [Homo sapiens] Length = 1116 Score = 38.9 bits (89), Expect = 0.011 Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 12/216 (5%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +LR+ +++P I+ I +A YI V + + L AV G+ V+ + Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 481 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ R+G L+V + P A++ Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANG-EPTWALLL 540 Query: 358 YGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLM 417 I I I+ ++ + S + Y L V R RP + Sbjct: 541 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSF 600 Query: 418 TLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFL 453 +S+ L L I S W Y V +++GL++ ++ Sbjct: 601 LGMSLCLALMFICS---W-YYALVAMLIAGLIYKYI 632 >gi|110224458 solute carrier family 12, member 6 isoform e [Homo sapiens] Length = 1135 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 493 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 551 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 552 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 610 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 611 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 644 >gi|110224456 solute carrier family 12, member 6 isoform d [Homo sapiens] Length = 1141 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 499 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 557 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 558 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 616 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 617 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 650 >gi|110224454 solute carrier family 12, member 6 isoform c [Homo sapiens] Length = 1091 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600 >gi|110224452 solute carrier family 12, member 6 isoform c [Homo sapiens] Length = 1091 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 449 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 566 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 567 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600 >gi|4826780 solute carrier family 12, member 6 isoform b [Homo sapiens] Length = 1099 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 457 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 515 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 516 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 574 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 575 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 608 >gi|110224449 solute carrier family 12, member 6 isoform a [Homo sapiens] Length = 1150 Score = 35.0 bits (79), Expect = 0.15 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 11/154 (7%) Query: 244 ELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL----Y 299 +L++ +++P+ I+ I L T+ L NV F +L+ + G+ V+ + Sbjct: 508 DLKDAQKSIPIGTILAI-LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 566 Query: 300 PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG--HMLKVLSYISVRRLTPAPAIIF 357 P+ W++ + FST GA + A RL+ ++ L+V + S P A++ Sbjct: 567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH-SKANGEPTWALLL 625 Query: 358 YGIIATIYIIPGDIN---SLVNYFSFAAWLFYGL 388 IA + I+ ++ +++ F +LF L Sbjct: 626 TAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 659 >gi|41327726 nicotinic acetylcholine receptor beta 1 subunit precursor [Homo sapiens] Length = 501 Score = 33.5 bits (75), Expect = 0.45 Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 16/109 (14%) Query: 332 GREGHMLKVLSYISVRRL-------TPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWL 384 GREG +V+ Y+ +RR AP I+ + ++ +P D + FA Sbjct: 227 GREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFA--- 283 Query: 385 FYGLTILGLIVMRFTRKELERPIKVPVVIPVL---MTLISVFLVLAPII 430 L L + ++ K E + VP++I L M L++ ++L+ ++ Sbjct: 284 ---LLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVVV 329 >gi|31881740 solute carrier family 12 (potassium/chloride transporters), member 9 [Homo sapiens] Length = 914 Score = 33.5 bits (75), Expect = 0.45 Identities = 36/186 (19%), Positives = 79/186 (42%), Gaps = 13/186 (6%) Query: 213 GAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNV 272 GA ++ ++ +NG ++ EL++P R +PL I+ + Y+L+ Sbjct: 262 GAVMNFASVFAVLFNGCTGIMAGANMS---GELKDPSRAIPLGTIVAVAYTFFVYVLL-- 316 Query: 273 SYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAG 332 + + T L + F L+P ++ ++ + + A+ + A R+++ Sbjct: 317 FFLSSFTCDRTLLQEDYGF-FRAISLWPPLVLIGIYA--TALSASMSSLIGASRILHALA 373 Query: 333 REGHMLKVLSYISV--RRLTPAPAIIFYGIIATIYIIPGDINSL---VNYFSFAAWLFYG 387 R+ +L+ V R P A+++ + + ++ G +N+L V F A+ Sbjct: 374 RDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVD 433 Query: 388 LTILGL 393 L+ L L Sbjct: 434 LSCLSL 439 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.142 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,322,131 Number of Sequences: 37866 Number of extensions: 706808 Number of successful extensions: 2211 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2144 Number of HSP's gapped (non-prelim): 53 length of query: 487 length of database: 18,247,518 effective HSP length: 106 effective length of query: 381 effective length of database: 14,233,722 effective search space: 5423048082 effective search space used: 5423048082 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.