Search of human proteins with 100913189

Search of human proteins with 100913189

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|100913189 AMP-activated protein kinase gamma2 subunit
isoform b [Homo sapiens]
         (328 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|100913192 AMP-activated protein kinase gamma2 subunit isoform...   643   0.0  
gi|100913189 AMP-activated protein kinase gamma2 subunit isoform...   643   0.0  
gi|33186925 AMP-activated protein kinase gamma2 subunit isoform ...   643   0.0  
gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1 su...   473   e-134
gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3 ...   420   e-117
gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1 s...   370   e-103
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi...    30   2.9  
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]          30   3.8  

>gi|100913192 AMP-activated protein kinase gamma2 subunit isoform c
           [Homo sapiens]
          Length = 525

 Score =  643 bits (1659), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 60
           MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV
Sbjct: 198 MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 257

Query: 61  RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 120
           RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL
Sbjct: 258 RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 317

Query: 121 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 180
           VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM
Sbjct: 318 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 377

Query: 181 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 240
           KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL
Sbjct: 378 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 437

Query: 241 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 300
           AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI
Sbjct: 438 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 497

Query: 301 VGIISLSDILQALILTPAGAKQKETETE 328
           VGIISLSDILQALILTPAGAKQKETETE
Sbjct: 498 VGIISLSDILQALILTPAGAKQKETETE 525


>gi|100913189 AMP-activated protein kinase gamma2 subunit isoform b
           [Homo sapiens]
          Length = 328

 Score =  643 bits (1659), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 60
           MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV
Sbjct: 1   MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 60

Query: 61  RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 120
           RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL
Sbjct: 61  RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 120

Query: 121 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 180
           VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM
Sbjct: 121 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 180

Query: 181 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 240
           KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL
Sbjct: 181 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 240

Query: 241 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 300
           AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI
Sbjct: 241 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 300

Query: 301 VGIISLSDILQALILTPAGAKQKETETE 328
           VGIISLSDILQALILTPAGAKQKETETE
Sbjct: 301 VGIISLSDILQALILTPAGAKQKETETE 328


>gi|33186925 AMP-activated protein kinase gamma2 subunit isoform a
           [Homo sapiens]
          Length = 569

 Score =  643 bits (1659), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 60
           MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV
Sbjct: 242 MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 301

Query: 61  RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 120
           RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL
Sbjct: 302 RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 361

Query: 121 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 180
           VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM
Sbjct: 362 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 421

Query: 181 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 240
           KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL
Sbjct: 422 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 481

Query: 241 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 300
           AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI
Sbjct: 482 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 541

Query: 301 VGIISLSDILQALILTPAGAKQKETETE 328
           VGIISLSDILQALILTPAGAKQKETETE
Sbjct: 542 VGIISLSDILQALILTPAGAKQKETETE 569


>gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 1 [Homo sapiens]
          Length = 331

 Score =  473 bits (1218), Expect = e-134
 Identities = 233/303 (76%), Positives = 270/303 (89%)

Query: 14  DSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSF 73
           +S + VY  FM+SH+CYD++PTSSKLVVFDT+LQVKKAFFALV NGVRAAPLW+SKKQSF
Sbjct: 23  ESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSF 82

Query: 74  VGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAV 133
           VGMLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV
Sbjct: 83  VGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAV 142

Query: 134 YSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYH 193
            SLI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY 
Sbjct: 143 SSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202

Query: 194 NIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITV 253
           NIA +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++V
Sbjct: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262

Query: 254 TQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQAL 313
           T+ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL
Sbjct: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322

Query: 314 ILT 316
           +LT
Sbjct: 323 VLT 325


>gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3
           subunit [Homo sapiens]
          Length = 489

 Score =  420 bits (1079), Expect = e-117
 Identities = 200/316 (63%), Positives = 267/316 (84%), Gaps = 1/316 (0%)

Query: 4   KLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAA 63
           KL ++DE +    + +YMRFM+ H CYD + TSSKLV+FDT L++KKAFFALVANGVRAA
Sbjct: 169 KLGWDDE-LRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAA 227

Query: 64  PLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNI 123
           PLW+SKKQSFVGMLTITDFI +LHRYY+SP+VQIYE+E+HKIETWRE+YLQ  FKPLV+I
Sbjct: 228 PLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPLVSI 287

Query: 124 SPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQN 183
           SP+ SLF+AVY+LIKN+IHRLPV+DP+SGN L+ILTHKR+LKFL +F S +P+P+F+ + 
Sbjct: 288 SPNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRT 347

Query: 184 LDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAE 243
           + +LGIGT+ ++A +    PI+ AL+IFV+RR+SALPVV+E G+VV +YS+FDVI+LAA+
Sbjct: 348 IQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQ 407

Query: 244 KTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGI 303
           +TYN+LD++V +AL+ R+   EGV+ C   E L  ++DRI R +VHRLV+V+E   ++G+
Sbjct: 408 QTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGV 467

Query: 304 ISLSDILQALILTPAG 319
           +SLSDILQAL+L+PAG
Sbjct: 468 VSLSDILQALVLSPAG 483


>gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 2 [Homo sapiens]
          Length = 247

 Score =  370 bits (950), Expect = e-103
 Identities = 184/241 (76%), Positives = 213/241 (88%)

Query: 76  MLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYS 135
           MLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV S
Sbjct: 1   MLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSS 60

Query: 136 LIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNI 195
           LI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY NI
Sbjct: 61  LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANI 120

Query: 196 AFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQ 255
           A +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++VT+
Sbjct: 121 AMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTK 180

Query: 256 ALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALIL 315
           ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL+L
Sbjct: 181 ALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 240

Query: 316 T 316
           T
Sbjct: 241 T 241


>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
           sapiens]
          Length = 607

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 36/164 (21%)

Query: 4   KLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAA 63
           +L FE ++ E+ E     R  R+ +   + P S++L+  D    +++ +           
Sbjct: 82  RLHFERDSREEVE-----RRKRAAREQVLQPVSAELLELD----IREVYQPGSVLDFPRR 132

Query: 64  PLW--ESKKQSFVGM--LTITDFINILHRYYKSPMVQIYELEEHKIETWRELY------- 112
           P W  E  K+  +     +  D++  +H  Y S  +  +E   H +ETWR+L+       
Sbjct: 133 PPWSYEMSKEQLMSQEERSFQDYLGKIHGAYSSEKLSYFE---HNLETWRQLWRVLEMSD 189

Query: 113 ----LQETFKPLVNISPDASLFDAVYS-------LIKNKIHRLP 145
               + +   P+VN  P  +L++ V         L+ NK+   P
Sbjct: 190 IVLLITDIRHPVVNFPP--ALYEYVTGELGLALVLVLNKVDLAP 231


>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
          Length = 326

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 7/68 (10%)

Query: 80  TDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLI-- 137
           T  I  LH + K+ +V+   LE  K     ++ + +T +PL+NI  D +L D VY L+  
Sbjct: 29  TTIIECLHSFCKTCIVRY--LETSKYCPICDVQVHKT-RPLLNIRSDKTLQDIVYKLVPG 85

Query: 138 --KNKIHR 143
             KN++ R
Sbjct: 86  LFKNEMKR 93


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,809,328
Number of Sequences: 37866
Number of extensions: 433362
Number of successful extensions: 884
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 869
Number of HSP's gapped (non-prelim): 8
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.