Guide to the Human Genome
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Search of human proteins with 186928856

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|186928856 solute carrier family 25, member 19 [Homo sapiens]       649   0.0  
gi|186928860 solute carrier family 25, member 19 [Homo sapiens]       649   0.0  
gi|186928858 solute carrier family 25, member 19 [Homo sapiens]       649   0.0  
gi|27544933 solute carrier family 25, member 16 [Homo sapiens]        126   2e-29
gi|60460887 solute carrier family 25, member 42 [Homo sapiens]        118   8e-27
gi|239755176 PREDICTED: similar to solute carrier family 25, mem...   115   7e-26
gi|239755174 PREDICTED: similar to solute carrier family 25, mem...   115   7e-26
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ...   115   7e-26
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ...   115   7e-26
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ...   115   7e-26
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ...   115   7e-26
gi|48476342 solute carrier family 25, member 23 [Homo sapiens]        110   2e-24
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ...   109   3e-24
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s...   109   3e-24
gi|21687151 mitochondrial solute carrier protein [Homo sapiens]       105   7e-23
gi|116235462 solute carrier family 25, member 45 isoform a [Homo...    99   7e-21
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho...    96   3e-20
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H...    96   3e-20
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade...    94   2e-19
gi|46094065 mitochondrial carrier family protein [Homo sapiens]        93   3e-19
gi|13259541 uncoupling protein 2 [Homo sapiens]                        92   6e-19
gi|149274643 solute carrier family 25, member 28 [Homo sapiens]        92   6e-19
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit...    91   1e-18
gi|86198310 solute carrier family 25, member 29 [Homo sapiens]         91   1e-18
gi|58197562 solute carrier family 25, member 30 [Homo sapiens]         91   2e-18
gi|156071459 solute carrier family 25, member 5 [Homo sapiens]         91   2e-18
gi|6031192 solute carrier family 25 member 3 isoform a precursor...    89   5e-18
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]           89   5e-18
gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]        89   7e-18
gi|4505775 solute carrier family 25 member 3 isoform b precursor...    89   7e-18

>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  649 bits (1674), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60
           MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH
Sbjct: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60

Query: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120
           GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV
Sbjct: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
           TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240

Query: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300
           KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF
Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300

Query: 301 FSYEFFCNVFHCMNRTASQR 320
           FSYEFFCNVFHCMNRTASQR
Sbjct: 301 FSYEFFCNVFHCMNRTASQR 320


>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  649 bits (1674), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60
           MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH
Sbjct: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60

Query: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120
           GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV
Sbjct: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
           TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240

Query: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300
           KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF
Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300

Query: 301 FSYEFFCNVFHCMNRTASQR 320
           FSYEFFCNVFHCMNRTASQR
Sbjct: 301 FSYEFFCNVFHCMNRTASQR 320


>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score =  649 bits (1674), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60
           MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH
Sbjct: 1   MVGYDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYH 60

Query: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120
           GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV
Sbjct: 61  GILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV 120

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
           TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240

Query: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300
           KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF
Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300

Query: 301 FSYEFFCNVFHCMNRTASQR 320
           FSYEFFCNVFHCMNRTASQR
Sbjct: 301 FSYEFFCNVFHCMNRTASQR 320


>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
          Length = 332

 Score =  126 bits (317), Expect = 2e-29
 Identities = 91/311 (29%), Positives = 148/311 (47%), Gaps = 40/311 (12%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG ++G   +  ++P D +K+  Q  +          K+ G+  A R + Q+EG    +
Sbjct: 41  LAGGIAGCCAKTTVAPLDRVKVLLQAHNHHY-------KHLGVFSALRAVPQKEGFLGLY 93

Query: 80  KGHVPAQILSIGYGAVQFLSFE-----MLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
           KG+    I    YGA+QF++FE     + T+L   G V+         + G +A   A +
Sbjct: 94  KGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVH-------RLMAGSMAGMTAVI 146

Query: 135 TVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQV-FYKGLAPTLIAIFPYAGL 191
             +P+D++R R A Q  GE   Y  + HA  T+Y  EG    FY+GL PT++ + PYAG+
Sbjct: 147 CTYPLDMVRVRLAFQVKGEHS-YTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGV 205

Query: 192 QFSCYSSLKHLYKWAIPA----EGKKNENLQ------NLLCGSGAGVISKTLTYPLDLFK 241
            F  + +LK +     P         N N+       NLLCG  AG I++T++YP D+ +
Sbjct: 206 SFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTR 265

Query: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG-ALGFFKGLSPSLLKAALSTGFMF 300
           +R+Q+G          +  +   + D  K V    G   G ++GLS + ++   S    F
Sbjct: 266 RRMQLG------TVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAF 319

Query: 301 FSYEFFCNVFH 311
            +YE     FH
Sbjct: 320 TTYELMKQFFH 330



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 60/185 (32%), Positives = 91/185 (49%), Gaps = 17/185 (9%)

Query: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
           F+ GG+A C A  TV P+D ++    A      +  +  A+  + + EG    YKG    
Sbjct: 40  FLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAM 99

Query: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241
           +I IFPY  +QF  +   K L    +   G    ++  L+ GS AG+ +   TYPLD+ +
Sbjct: 100 MIRIFPYGAIQFMAFEHYKTLITTKLGISG----HVHRLMAGSMAGMTAVICTYPLDMVR 155

Query: 242 KRL--QVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGA-LGFFKGLSPSLLKAALSTGF 298
            RL  QV G EH+         Y G++   K +  KEG   GF++GL P++L  A   G 
Sbjct: 156 VRLAFQVKG-EHS---------YTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGV 205

Query: 299 MFFSY 303
            FF++
Sbjct: 206 SFFTF 210



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 9/90 (10%)

Query: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
           L++ L G  AG  +KT   PLD  K  LQ     +         ++ G+    + V QKE
Sbjct: 37  LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHY---------KHLGVFSALRAVPQKE 87

Query: 277 GALGFFKGLSPSLLKAALSTGFMFFSYEFF 306
           G LG +KG    +++        F ++E +
Sbjct: 88  GFLGLYKGNGAMMIRIFPYGAIQFMAFEHY 117


>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
          Length = 318

 Score =  118 bits (295), Expect = 8e-27
 Identities = 79/291 (27%), Positives = 148/291 (50%), Gaps = 31/291 (10%)

Query: 22  GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDP-SAKYHGILQASRQILQEEGPTAFWK 80
           G+++G + +  ++P D  KI FQ+  +R S  +     Y+  L         EG  + W+
Sbjct: 40  GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLN--------EGFLSLWR 91

Query: 81  GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSV----HFVCGGLAACMATLTV 136
           G+    +  + Y A+QF + E    ++  GS Y  R  ++        G LA   A    
Sbjct: 92  GNSATMVRVVPYAAIQFSAHEEYKRIL--GSYYGFRGEALPPWPRLFAGALAGTTAASLT 149

Query: 137 HPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY 196
           +P+D++R R A   + ++Y+ + H    + R EG +  Y G  PT++ + PYAGL F  Y
Sbjct: 150 YPLDLVRARMAVTPK-EMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTY 208

Query: 197 SSLKHLYKWAIPAEGKKNE-NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE-HARA 254
            +LK L++      G++     + ++ G+ AG+I ++ +YPLD+ ++R+Q  G   + RA
Sbjct: 209 ETLKSLHR---EYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRA 265

Query: 255 AFGQVRRYKGLMDCAKQVLQKEGAL-GFFKGLSPSLLKAALSTGFMFFSYE 304
           +  +  R          ++++EGA+ G +KGLS + +K  ++ G  F +++
Sbjct: 266 SIARTLR---------TIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 28/195 (14%)

Query: 21  AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
           AG+++G    +L  P D+++ R  +         P   Y  I     +I +EEG    + 
Sbjct: 137 AGALAGTTAASLTYPLDLVRARMAV--------TPKEMYSNIFHVFIRISREEGLKTLYH 188

Query: 81  GHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF---VCGGLAACMATLTVH 137
           G +P  +  I Y  + F ++E L  L HR   Y  R     F   + G  A  +     +
Sbjct: 189 GFMPTVLGVIPYAGLSFFTYETLKSL-HR--EYSGRRQPYPFERMIFGACAGLIGQSASY 245

Query: 138 PVDVLRTRFAAQG-----EPKVYNTLRHAVGTMYRSEGP-QVFYKGLAPTLIAIFPYAGL 191
           P+DV+R R    G        +  TLR    T+ R EG  +  YKGL+   +      G+
Sbjct: 246 PLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVRGLYKGLSMNWVKGPIAVGI 301

Query: 192 QFSCYS----SLKHL 202
            F+ +      L+HL
Sbjct: 302 SFTTFDLMQIMLRHL 316



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
           L +LL G+ AG ++KT   PLD  K   QV     +     +V  Y  L          E
Sbjct: 34  LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL---------NE 84

Query: 277 GALGFFKGLSPSLLKAALSTGFMFFSYE 304
           G L  ++G S ++++        F ++E
Sbjct: 85  GFLSLWRGNSATMVRVVPYAAIQFSAHE 112


>gi|239755176 PREDICTED: similar to solute carrier family 25, member
           25 isoform 2 [Homo sapiens]
          Length = 469

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 455 VVYENLK 461



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 352 IDLAVYETLKNAW 364



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265


>gi|239755174 PREDICTED: similar to solute carrier family 25, member
           25 isoform 1 [Homo sapiens]
          Length = 503

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 277

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 278 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 336 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 395 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 448

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 449 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 370

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 371 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 430

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 431 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 489 VVYENLK 495



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 283 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 336 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 386 IDLAVYETLKNAW 398



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 272

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 273 ARSLWRGNGINVLKIAPESAIKFMAYE 299


>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
           sapiens]
          Length = 489

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 211 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 263

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 264 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 321

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 322 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 380

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 381 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 434

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 435 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 478



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 305 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 356

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 357 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 416

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 417 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 474

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 475 VVYENLK 481



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 268

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 269 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 321

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 322 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 371

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 372 IDLAVYETLKNAW 384



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 258

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 259 ARSLWRGNGINVLKIAPESAIKFMAYE 285


>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
           sapiens]
          Length = 469

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 455 VVYENLK 461



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 352 IDLAVYETLKNAW 364



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265


>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
           sapiens]
          Length = 366

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 88  VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 140

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 141 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 198

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 199 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 257

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 258 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 311

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 312 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 355



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 182 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 233

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 234 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 293

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 294 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 351

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 352 VVYENLK 358



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 86  HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 145

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 146 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 198

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 199 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 248

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 249 IDLAVYETLKNAW 261



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 85  RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 135

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 136 ARSLWRGNGINVLKIAPESAIKFMAYE 162


>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
           sapiens]
          Length = 503

 Score =  115 bits (287), Expect = 7e-26
 Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG  +G V+R   +P D +K+  Q+   R +         GI+    Q+++E G  + W
Sbjct: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 277

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +  LV  GS  +        V G LA  +A  +++P+
Sbjct: 278 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR A +   + Y+ +      +   EG   FYKG  P ++ I PYAG+  + Y +L
Sbjct: 336 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +                L CG+ +    +  +YPL L + R+Q      A+A+    
Sbjct: 395 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 448

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +    K +L+ EGA G ++GL+P+ +K   +    +  YE
Sbjct: 449 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492



 Score = 85.9 bits (211), Expect = 4e-17
 Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G + ++ I P +V+K R  L+         + +Y G+L  +R+IL  EG  AF+
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 370

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
           KG+VP  +  I Y  +    +E L    L H           V   CG +++    L  +
Sbjct: 371 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 430

Query: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
           P+ ++RTR  AQ    G P+V  T+      + R+EG    Y+GLAP  + + P   + +
Sbjct: 431 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488

Query: 194 SCYSSLK 200
             Y +LK
Sbjct: 489 VVYENLK 495



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)

Query: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
           H V GG A  ++     P+D L+              +      M R  G +  ++G   
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
            ++ I P + ++F  Y  +K L        G   E L   + L+ GS AG I+++  YP+
Sbjct: 283 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 335

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           ++ K R+          A  +  +Y G++DCA+++L +EG   F+KG  P++L      G
Sbjct: 336 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385

Query: 298 FMFFSYEFFCNVF 310
                YE   N +
Sbjct: 386 IDLAVYETLKNAW 398



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
           ++L+ G GAG +S+T T PLD  K  +QV    HA  +        G++    Q++++ G
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 272

Query: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
           A   ++G   ++LK A  +   F +YE
Sbjct: 273 ARSLWRGNGINVLKIAPESAIKFMAYE 299


>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
          Length = 468

 Score =  110 bits (274), Expect = 2e-24
 Identities = 73/285 (25%), Positives = 133/285 (46%), Gaps = 17/285 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG+V+G V+R   +P D +K+  Q+   + +R +       IL   R ++ E G  + W
Sbjct: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN-------ILGGLRSMVLEGGIRSLW 242

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G+    +      A++F+++E +   +      +       FV G LA   A   ++P+
Sbjct: 243 RGNGINVLKIAPESAIKFMAYEQIKRAIL--GQQETLHVQERFVAGSLAGATAQTIIYPM 300

Query: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
           +VL+TR   +   + Y  L      +   EGP+ FY+G  P ++ I PYAG+  + Y +L
Sbjct: 301 EVLKTRLTLRRTGQ-YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359

Query: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
           K+ +      +      L  L CG+ +    +  +YPL L + R+Q      A    G  
Sbjct: 360 KNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA----QASIEGGPQ 415

Query: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
               GL+   + +L +EG  G ++G++P+ +K   +    +  YE
Sbjct: 416 LSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457



 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 52/189 (27%), Positives = 96/189 (50%), Gaps = 20/189 (10%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAGS++G   + +I P +V+K R  L+         + +Y G+L  +R+IL+ EGP AF+
Sbjct: 284 VAGSLAGATAQTIIYPMEVLKTRLTLRR--------TGQYKGLLDCARRILEREGPRAFY 335

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDARE--FSVHFVCGGLAACMATLTVH 137
           +G++P  +  I Y  +    +E L     +   +D+ +    V   CG +++    +  +
Sbjct: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395

Query: 138 PVDVLRTRFAAQ----GEPKV--YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
           P+ ++RTR  AQ    G P++     LRH +      EG +  Y+G+AP  + + P   +
Sbjct: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILS----QEGMRGLYRGIAPNFMKVIPAVSI 451

Query: 192 QFSCYSSLK 200
            +  Y ++K
Sbjct: 452 SYVVYENMK 460



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 14/186 (7%)

Query: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
           V G +A  ++     P+D L+              +   + +M    G +  ++G    +
Sbjct: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249

Query: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKK 242
           + I P + ++F  Y  +K     AI  + +     +  + GS AG  ++T+ YP+++ K 
Sbjct: 250 LKIAPESAIKFMAYEQIKR----AILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKT 305

Query: 243 RLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFS 302
           RL +           +  +YKGL+DCA+++L++EG   F++G  P++L      G     
Sbjct: 306 RLTLR----------RTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355

Query: 303 YEFFCN 308
           YE   N
Sbjct: 356 YETLKN 361



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 14/103 (13%)

Query: 207 IPAEGKKNENL-----QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
           +P E  K E L     + L+ G+ AG +S+T T PLD  K  +QV   +  R        
Sbjct: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL------- 223

Query: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
              ++   + ++ + G    ++G   ++LK A  +   F +YE
Sbjct: 224 --NILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYE 264


>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
           sapiens]
          Length = 477

 Score =  109 bits (273), Expect = 3e-24
 Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG ++G V+R   +P D +KI  Q+     S+SD    + G     RQ+++E G  + W
Sbjct: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 251

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
           +G+    I      AV+F ++E   +L+   G      E    F+ G +A   A   ++P
Sbjct: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 308

Query: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198
           ++V++TR A  G+   Y+ +      + + EG   FYKG  P L+ I PYAG+  + Y  
Sbjct: 309 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367

Query: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
           LK  Y     A+   N  +  LL CG+ +    +  +YPL L + R+Q            
Sbjct: 368 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426

Query: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
            V  +       ++++ KEG  G ++G++P+ +K   + G  +  YE
Sbjct: 427 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%)

Query: 9   DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
           +G+    F+  ++GS++G   +  I P +V+K R  +          + +Y GI   +++
Sbjct: 282 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 333

Query: 69  ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126
           IL+ EG  AF+KG+VP  +  I Y  +    +E+L          D+    V  +  CG 
Sbjct: 334 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 393

Query: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179
           L++    L  +P+ ++RTR  AQ    G P++     + VG   R    EG    Y+G+ 
Sbjct: 394 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 448

Query: 180 PTLIAIFPYAGLQFSCYSSLK 200
           P  + + P  G+ +  Y ++K
Sbjct: 449 PNFMKVLPAVGISYVVYENMK 469



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%)

Query: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268
           E K  +  + LL G  AG +S+T T PLD  K  +QV G +  +   FG  R        
Sbjct: 188 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 239

Query: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
             Q++++ G    ++G   +++K A  T   F++YE
Sbjct: 240 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 273


>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
           sapiens]
          Length = 458

 Score =  109 bits (273), Expect = 3e-24
 Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG ++G V+R   +P D +KI  Q+     S+SD    + G     RQ+++E G  + W
Sbjct: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 232

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
           +G+    I      AV+F ++E   +L+   G      E    F+ G +A   A   ++P
Sbjct: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 289

Query: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198
           ++V++TR A  G+   Y+ +      + + EG   FYKG  P L+ I PYAG+  + Y  
Sbjct: 290 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348

Query: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
           LK  Y     A+   N  +  LL CG+ +    +  +YPL L + R+Q            
Sbjct: 349 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407

Query: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
            V  +       ++++ KEG  G ++G++P+ +K   + G  +  YE
Sbjct: 408 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%)

Query: 9   DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
           +G+    F+  ++GS++G   +  I P +V+K R  +          + +Y GI   +++
Sbjct: 263 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 314

Query: 69  ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126
           IL+ EG  AF+KG+VP  +  I Y  +    +E+L          D+    V  +  CG 
Sbjct: 315 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 374

Query: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179
           L++    L  +P+ ++RTR  AQ    G P++     + VG   R    EG    Y+G+ 
Sbjct: 375 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 429

Query: 180 PTLIAIFPYAGLQFSCYSSLK 200
           P  + + P  G+ +  Y ++K
Sbjct: 430 PNFMKVLPAVGISYVVYENMK 450



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%)

Query: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268
           E K  +  + LL G  AG +S+T T PLD  K  +QV G +  +   FG  R        
Sbjct: 169 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 220

Query: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
             Q++++ G    ++G   +++K A  T   F++YE
Sbjct: 221 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 254


>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
          Length = 341

 Score =  105 bits (261), Expect = 7e-23
 Identities = 79/300 (26%), Positives = 147/300 (49%), Gaps = 20/300 (6%)

Query: 9   DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
           DGR     ++  AG ++G ++ +L +P ++  +  Q+   R     P A  H + +A   
Sbjct: 7   DGRLTGGQRLLCAG-LAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRA--- 62

Query: 69  ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLA 128
               EG  A WKG+  A +      AVQ  ++     L      + ++  S+  + G LA
Sbjct: 63  ----EGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSI--MAGSLA 116

Query: 129 ACMATLTVHPVDVLRTRFAAQG--EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIF 186
             ++T+  +P D+++TR   Q   EP  Y  L HA  T+Y+ EG    Y+G++ T++   
Sbjct: 117 GMVSTIVTYPTDLIKTRLIMQNILEPS-YRGLLHAFSTIYQQEGFLALYRGVSLTVVGAL 175

Query: 187 PYAGLQFSCYSSLKHLYKWAIPAEG-KKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQ 245
           P++      Y +L+ +  W  P +     +N  N+     A  +++TL++P +  K+++Q
Sbjct: 176 PFSAGSLLVYMNLEKI--WNGPRDQFSLPQNFANVCL---AAAVTQTLSFPFETVKRKMQ 230

Query: 246 VGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
                +   + G    + G +DC +Q+++ +G LG + GL+ +LLK     G MF ++EF
Sbjct: 231 AQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEF 289


>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
           sapiens]
          Length = 288

 Score = 98.6 bits (244), Expect = 7e-21
 Identities = 79/299 (26%), Positives = 128/299 (42%), Gaps = 36/299 (12%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           VAG +SG +   L  PFD +K+R Q Q            Y GI+    +I + E    F+
Sbjct: 7   VAGWISGALGLVLGHPFDTVKVRLQTQ----------TTYRGIVDCMVKIYRHESLLGFF 56

Query: 80  KG-HVP----AQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
           KG   P    A + S+ +G V   +  +LT   H+        +   F+ G     +   
Sbjct: 57  KGMSFPIASIAVVNSVLFG-VYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAY 115

Query: 135 TVHPVDVLRTRFAAQGEPKV--------YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIF 186
            + P D+++ R   Q EP+         Y    H   +++R EGP+  ++G     +   
Sbjct: 116 CLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDT 175

Query: 187 PYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQV 246
           P  G+ F  Y  L   Y      EG+   +   L+ G  AG+ S     PLD+ K R+Q+
Sbjct: 176 PTVGIYFITYEGLCRQYT----PEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQM 231

Query: 247 GGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
            G           R Y+G++DC    +++EG   FF+G++ +  +A       F SYE+
Sbjct: 232 DGLRR--------RVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEY 282



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 9/191 (4%)

Query: 18  VAVAGSVSGLVTRALISPFDVIKIRFQLQHE-RLSRSDPSAKYHGILQASRQILQEEGPT 76
           + +AG   G +    ++PFD+IK+R Q Q E R     P  +Y G +  +  I +EEGP 
Sbjct: 102 IFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPR 161

Query: 77  AFWKGHVPAQILSIGYGAVQFLSFE-MLTELVHRGSVYDAREFSVHFVCGGLAACMATLT 135
             ++G     +       + F+++E +  +    G    +   +   V GG A   + + 
Sbjct: 162 GLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSS---ATVLVAGGFAGIASWVA 218

Query: 136 VHPVDVLRTRFAAQG-EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
             P+D++++R    G   +VY  +   + +  R EG  VF++G+       FP   + F 
Sbjct: 219 ATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFL 278

Query: 195 CYSSLKHLYKW 205
            Y   ++L +W
Sbjct: 279 SY---EYLLRW 286



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 6/191 (3%)

Query: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
           FV G ++  +  +  HP D ++ R   Q     Y  +   +  +YR E    F+KG++  
Sbjct: 6   FVAGWISGALGLVLGHPFDTVKVRLQTQ---TTYRGIVDCMVKIYRHESLLGFFKGMSFP 62

Query: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKN--ENLQNLLCGSGAGVISKTLTYPLDL 239
           + +I     + F  YS+   +       E +      +   L G   G +      P DL
Sbjct: 63  IASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDL 122

Query: 240 FKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFM 299
            K RLQ      A+       RY+G + CA  + ++EG  G F+G     L+   + G  
Sbjct: 123 IKVRLQNQTEPRAQPG-SPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIY 181

Query: 300 FFSYEFFCNVF 310
           F +YE  C  +
Sbjct: 182 FITYEGLCRQY 192



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 8   PDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASR 67
           P+G+N +   V VAG  +G+ +    +P D+IK R Q+   R         Y G+L    
Sbjct: 194 PEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLR------RRVYQGMLDCMV 247

Query: 68  QILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEML 103
             +++EG   F++G       +    AV FLS+E L
Sbjct: 248 SSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 283



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 12/87 (13%)

Query: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
           ++  + G  +G +   L +P D  K RLQ                Y+G++DC  ++ + E
Sbjct: 3   VEEFVAGWISGALGLVLGHPFDTVKVRLQT------------QTTYRGIVDCMVKIYRHE 50

Query: 277 GALGFFKGLSPSLLKAALSTGFMFFSY 303
             LGFFKG+S  +   A+    +F  Y
Sbjct: 51  SLLGFFKGMSFPIASIAVVNSVLFGVY 77


>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
           sapiens]
          Length = 325

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 71/287 (24%), Positives = 128/287 (44%), Gaps = 15/287 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           V G ++ +V      P D+ K R Q+Q + +       KY G+  A  +I +EEG  A +
Sbjct: 45  VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTEL-VHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
            G  PA +    YG ++   ++ L  L V R    +     ++ +CG ++  +++   +P
Sbjct: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANP 161

Query: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS- 197
            DVL+ R  AQG      ++  +   +Y+ EG +  ++G+ PT        G++   Y  
Sbjct: 162 TDVLKIRMQAQGS-LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220

Query: 198 SLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
           + KHL    +  +      + +  CG    + S     P+D+ + R+      + RA  G
Sbjct: 221 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASN----PVDVVRTRMM-----NQRAIVG 271

Query: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
            V  YKG +D   ++ + EG    +KG  P+ L+        F +YE
Sbjct: 272 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318



 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 23/184 (12%)

Query: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
           FV GGLA+ +A     PVD+ +TR   QG+          Y  + HA+  + + EG    
Sbjct: 44  FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103

Query: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQ-NLLCGSGAGVISKTL 233
           Y G+AP L+    Y  ++   Y SLK L+      E  ++E L  N++CG  +GVIS T+
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLF-----VERLEDETLLINMICGVVSGVISSTI 158

Query: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
             P D+ K R+Q  G     +  G              + Q+EG  G ++G+ P+  +AA
Sbjct: 159 ANPTDVLKIRMQAQGSLFQGSMIGSF----------IDIYQQEGTRGLWRGVVPTAQRAA 208

Query: 294 LSTG 297
           +  G
Sbjct: 209 IVVG 212



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 25/78 (32%), Positives = 48/78 (61%), Gaps = 2/78 (2%)

Query: 216 NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQK 275
           N +  + G  A ++++  T+P+DL K RLQV G +   A F ++ +Y+G+     ++ ++
Sbjct: 40  NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQG-QSIDARFKEI-KYRGMFHALFRICKE 97

Query: 276 EGALGFFKGLSPSLLKAA 293
           EG L  + G++P+LL+ A
Sbjct: 98  EGVLALYSGIAPALLRQA 115



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           V+    GL      +P DV++ R   Q   +   D    Y G +    ++ + EG  A +
Sbjct: 240 VSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD---LYKGTVDGILKMWKHEGFFALY 296

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTEL 106
           KG  P  +    +  + F+++E L  L
Sbjct: 297 KGFWPNWLRLGPWNIIFFITYEQLKRL 323


>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
           sapiens]
          Length = 322

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 71/287 (24%), Positives = 128/287 (44%), Gaps = 15/287 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           V G ++ +V      P D+ K R Q+Q + +       KY G+  A  +I +EEG  A +
Sbjct: 42  VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 101

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTEL-VHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
            G  PA +    YG ++   ++ L  L V R    +     ++ +CG ++  +++   +P
Sbjct: 102 SGIAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANP 158

Query: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS- 197
            DVL+ R  AQG      ++  +   +Y+ EG +  ++G+ PT        G++   Y  
Sbjct: 159 TDVLKIRMQAQGS-LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 217

Query: 198 SLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
           + KHL    +  +      + +  CG    + S     P+D+ + R+      + RA  G
Sbjct: 218 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASN----PVDVVRTRMM-----NQRAIVG 268

Query: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
            V  YKG +D   ++ + EG    +KG  P+ L+        F +YE
Sbjct: 269 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 315



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 61/204 (29%), Positives = 96/204 (47%), Gaps = 27/204 (13%)

Query: 106 LVHRGSVYDAREFS----VHFVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKV 154
           ++H+ S   + E S      FV GGLA+ +A     PVD+ +TR   QG+          
Sbjct: 21  VIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIK 80

Query: 155 YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKN 214
           Y  + HA+  + + EG    Y G+AP L+    Y  ++   Y SLK L+      E  ++
Sbjct: 81  YRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLF-----VERLED 135

Query: 215 ENLQ-NLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVL 273
           E L  N++CG  +GVIS T+  P D+ K R+Q  G     +  G              + 
Sbjct: 136 ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSF----------IDIY 185

Query: 274 QKEGALGFFKGLSPSLLKAALSTG 297
           Q+EG  G ++G+ P+  +AA+  G
Sbjct: 186 QQEGTRGLWRGVVPTAQRAAIVVG 209



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           V+    GL      +P DV++ R   Q   +   D    Y G +    ++ + EG  A +
Sbjct: 237 VSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD---LYKGTVDGILKMWKHEGFFALY 293

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTEL 106
           KG  P  +    +  + F+++E L  L
Sbjct: 294 KGFWPNWLRLGPWNIIFFITYEQLKRL 320


>gi|13775208 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 31 [Homo
           sapiens]
          Length = 315

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 70/279 (25%), Positives = 124/279 (44%), Gaps = 20/279 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG V+  V++  ++P + +K+  Q+Q      S P A+Y G++    +I +E+G  +FW
Sbjct: 25  LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFFSFW 83

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDA---REFSVHFVCGGLAACMATLTV 136
           +G++   I      A+ F   +   +L   G   +    R F  +   GG A   +   V
Sbjct: 84  RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143

Query: 137 HPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
           +P+D  RTR         E + +  L   +  + +S+G    Y+G   ++  I  Y    
Sbjct: 144 YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203

Query: 193 FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
           F  Y ++K L       + KK   L +          S  L+YP D  ++R+ +   E  
Sbjct: 204 FGAYDTVKGLLP-----KPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAK 258

Query: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLK 291
           R       +YKG +DC  ++ Q EG   FF+G   ++L+
Sbjct: 259 R-------QYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 12/200 (6%)

Query: 112 VYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKV------YNTLRHAVGTM 165
           ++DA  F    + GG+AA ++   V P++ ++     Q   K       Y  +   +  +
Sbjct: 14  LFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRI 73

Query: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKK-NENLQNLLCGS 224
            R +G   F++G    +I  FP   L F+     K L+   +  E +     L NL  G 
Sbjct: 74  PREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGG 133

Query: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
            AG  S  + YPLD  + RL   G +  +    + R++KGL DC  ++ + +G  G ++G
Sbjct: 134 AAGATSLCVVYPLDFARTRL---GVDIGKGP--EERQFKGLGDCIMKIAKSDGIAGLYQG 188

Query: 285 LSPSLLKAALSTGFMFFSYE 304
              S+    +     F +Y+
Sbjct: 189 FGVSVQGIIVYRASYFGAYD 208


>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
          Length = 338

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 78/332 (23%), Positives = 137/332 (41%), Gaps = 41/332 (12%)

Query: 5   DPKPDGRNNTK---FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRS-------- 53
           DP+  G+   K    Q  +A     ++T  +++P DV+KIR Q Q+  L +         
Sbjct: 2   DPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNG 61

Query: 54  -----------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQ 96
                                 + G L A  +I++ EG  + W G  P  ++++    + 
Sbjct: 62  LMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIY 121

Query: 97  FLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYN 156
           F  ++ L+ L+   S     E  +  V G +A   A   + P++++RT+   Q +   Y 
Sbjct: 122 FTCYDQLSALLR--SKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM--QSKKFSYV 177

Query: 157 TLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
            L   V      +G    ++G APT++   P++ + +  Y  LK   KW     G     
Sbjct: 178 ELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILK---KWLCEKSGLYEPT 234

Query: 217 LQ-NLLCGSGAGVISKTLTYPLDLFK--KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVL 273
              N   G+ +G  +   T P D+ K  K+ Q+  +E  + +   +  +       K ++
Sbjct: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS---MPLHMSTWIIMKNIV 291

Query: 274 QKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
            K G  G F GL P L+K A +   M  +YEF
Sbjct: 292 AKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 20/204 (9%)

Query: 10  GRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
           G N T   + VAG V+      +ISP ++I+ + Q      S+     + H  +      
Sbjct: 137 GENETCIPI-VAGIVARFGAVTVISPLELIRTKMQ------SKKFSYVELHRFVSKK--- 186

Query: 70  LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVCGGLA 128
           + E+G  + W+G  P  +  + + A+ + ++E+L + L  +  +Y+   F ++F  G L+
Sbjct: 187 VSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-TFMINFTSGALS 245

Query: 129 ACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRS----EGPQVFYKGLAP 180
              A +   P DV++T+   Q       K+   L  +   + ++     G    + GL P
Sbjct: 246 GSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIP 305

Query: 181 TLIAIFPYAGLQFSCYSSLKHLYK 204
            LI I P   +  S Y   K  ++
Sbjct: 306 RLIKIAPACAIMISTYEFGKAFFQ 329


>gi|13259541 uncoupling protein 2 [Homo sapiens]
          Length = 309

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 77/293 (26%), Positives = 127/293 (43%), Gaps = 32/293 (10%)

Query: 21  AGSVSGLVTRALISPFDVIKIRFQLQHERLS--RSDPSAKYHGILQASRQILQEEGPTAF 78
           A  ++ L+T     P D  K+R Q+Q E     R+  SA+Y G++     +++ EGP + 
Sbjct: 23  AACIADLIT----FPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSL 78

Query: 79  WKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
           + G V      + + +V+   ++ + +   +GS + +       + G     +A     P
Sbjct: 79  YNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAS--IGSRLLAGSTTGALAVAVAQP 136

Query: 139 VDVLRTRFAAQ---GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
            DV++ RF AQ   G  + Y +  +A  T+ R EG +  +KG +P +         +   
Sbjct: 137 TDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVT 196

Query: 196 YSSLKHLYKWAIPAEGKKNENLQNLLC----GSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
           Y  +K        A  K N    +L C      GAG  +  +  P+D+ K R       +
Sbjct: 197 YDLIKD-------ALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTR-------Y 242

Query: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
             +A GQ   Y     CA  +LQKEG   F+KG  PS L+       MF +YE
Sbjct: 243 MNSALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 52/183 (28%), Positives = 93/183 (50%), Gaps = 10/183 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AGS +G +  A+  P DV+K+RFQ Q    +R+    +Y   + A + I +EEG    W
Sbjct: 121 LAGSTTGALAVAVAQPTDVVKVRFQAQ----ARAGGGRRYQSTVNAYKTIAREEGFRGLW 176

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           KG  P    +      + ++++++ + + + ++    +   HF     A    T+   PV
Sbjct: 177 KGTSPNVARNAIVNCAELVTYDLIKDALLKANLM-TDDLPCHFTSAFGAGFCTTVIASPV 235

Query: 140 DVLRTRF--AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197
           DV++TR+  +A G+   Y++  H   TM + EGP+ FYKG  P+ + +  +  + F  Y 
Sbjct: 236 DVVKTRYMNSALGQ---YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292

Query: 198 SLK 200
            LK
Sbjct: 293 QLK 295



 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 56/186 (30%), Positives = 91/186 (48%), Gaps = 21/186 (11%)

Query: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPK---------VYNTLRHAVGTMYRSE 169
           +V F+  G AAC+A L   P+D  + R   QGE +          Y  +   + TM R+E
Sbjct: 14  TVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTE 73

Query: 170 GPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGV 228
           GP+  Y GL   L     +A ++   Y S+K  Y      +G ++ ++   LL GS  G 
Sbjct: 74  GPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFY-----TKGSEHASIGSRLLAGSTTGA 128

Query: 229 ISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPS 288
           ++  +  P D+ K R Q      A+A  G  RRY+  ++  K + ++EG  G +KG SP+
Sbjct: 129 LAVAVAQPTDVVKVRFQ------AQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPN 182

Query: 289 LLKAAL 294
           + + A+
Sbjct: 183 VARNAI 188


>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
          Length = 364

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 76/315 (24%), Positives = 139/315 (44%), Gaps = 40/315 (12%)

Query: 4   YDPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGIL 63
           Y+  P G   T   VA  G+V+G++   ++ P D +K R Q       + DP+A+Y  +L
Sbjct: 63  YEALPAGATVTTHMVA--GAVAGILEHCVMYPIDCVKTRMQ-----SLQPDPAARYRNVL 115

Query: 64  QASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSF-------EMLTELVHRGSVYDAR 116
           +A  +I++ EG    W+      + + G G    L F       + L++++H G      
Sbjct: 116 EALWRIIRTEG---LWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGG----- 167

Query: 117 EFSVHFVCGGLAACMATL----TVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQ 172
             + H +  G A C+ATL     ++P +V++ R      P  Y+ +   V  ++++EG  
Sbjct: 168 --NSH-IANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSP--YHRVTDCVRAVWQNEGAG 222

Query: 173 VFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKT 232
            FY+     L    P+  + F  Y  L+  +        ++     ++L G+ AG ++  
Sbjct: 223 AFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFN-----PQRRYNPSSHVLSGACAGAVAAA 277

Query: 233 LTYPLDLFKKRLQVGGFEHARAAFGQVRRY-KGLMDCAKQVLQKEGALGFFKGLSPSLLK 291
            T PLD+ K  L     + + A    +  +  G+    + V Q  G   +F+G+   ++ 
Sbjct: 278 ATTPLDVCKTLLNT---QESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIY 334

Query: 292 AALSTGFMFFSYEFF 306
              ST   +  YEFF
Sbjct: 335 QIPSTAIAWSVYEFF 349



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 21/198 (10%)

Query: 13  NTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQE 72
           N+      AG V+ L+  A ++P +V+K R Q+ +         + YH +    R + Q 
Sbjct: 168 NSHIANGAAGCVATLLHDAAMNPAEVVKQRMQMYN---------SPYHRVTDCVRAVWQN 218

Query: 73  EGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMA 132
           EG  AF++ +     +++ + A+ F+++E L E  +    Y+    S H + G  A  +A
Sbjct: 219 EGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNP---SSHVLSGACAGAVA 275

Query: 133 TLTVHPVDVLRTRFAAQGEPKVYNT--------LRHAVGTMYRSEGPQVFYKGLAPTLIA 184
                P+DV +T    Q E    N+        +  A  T+Y+  G   +++G+   +I 
Sbjct: 276 AAATTPLDVCKTLLNTQ-ESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIY 334

Query: 185 IFPYAGLQFSCYSSLKHL 202
             P   + +S Y   K+L
Sbjct: 335 QIPSTAIAWSVYEFFKYL 352



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 15/199 (7%)

Query: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAA-QGEPKV-YNTLRHAVGTMYRSEGPQVFYK 176
           + H V G +A  +    ++P+D ++TR  + Q +P   Y  +  A+  + R+EG     +
Sbjct: 73  TTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMR 132

Query: 177 GLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYP 236
           GL  T     P   L F+CY  LK      I   G  N ++ N   G  A ++      P
Sbjct: 133 GLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGG--NSHIANGAAGCVATLLHDAAMNP 190

Query: 237 LDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALST 296
            ++ K+R+Q+    + R             DC + V Q EGA  F++  +  L       
Sbjct: 191 AEVVKQRMQMYNSPYHRVT-----------DCVRAVWQNEGAGAFYRSYTTQLTMNVPFQ 239

Query: 297 GFMFFSYEFFCNVFHCMNR 315
              F +YEF    F+   R
Sbjct: 240 AIHFMTYEFLQEHFNPQRR 258


>gi|21389315 solute carrier family 25 (mitochondrial carrier;
           citrate transporter), member 1 precursor [Homo sapiens]
          Length = 311

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 79/289 (27%), Positives = 127/289 (43%), Gaps = 24/289 (8%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG ++G +   +  P + +K + QL      RS P  +Y GI    RQ ++  G    +
Sbjct: 30  LAGGLAGGIEICITFPTEYVKTQLQLDE----RSHPP-RYRGIGDCVRQTVRSHGVLGLY 84

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCG-GLAACMATLTVHP 138
           +G       SI   AV+F  FE L+   H        + +   +CG G     A + V P
Sbjct: 85  RGLSSLLYGSIPKAAVRFGMFEFLSN--HMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCP 142

Query: 139 VDVLRTRFA---AQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
           ++ ++ +F        PK Y    H V  + R +G +  Y+GL  T++       ++F  
Sbjct: 143 METIKVKFIHDQTSPNPK-YRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFV 201

Query: 196 YSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAA 255
            +SL++ Y+   P   K    L   + G+ AG  S     PLD+ K R+Q  G E     
Sbjct: 202 MTSLRNWYRGDNP--NKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQ--GLE----- 252

Query: 256 FGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                +Y+   DC  Q+L+KEG   F+KG  P L +  L    +F  Y+
Sbjct: 253 ---AHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 298



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 9/105 (8%)

Query: 206 AIPAEGKKNENLQN--LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYK 263
           A PA GK         +L G  AG I   +T+P +  K +LQ+    H         RY+
Sbjct: 13  AAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPP-------RYR 65

Query: 264 GLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCN 308
           G+ DC +Q ++  G LG ++GLS  L  +       F  +EF  N
Sbjct: 66  GIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSN 110



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 8/172 (4%)

Query: 32  LISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIG 91
           ++ P + IK++F   H++ S   P+ KY G     R+I++E+G    ++G + A +L  G
Sbjct: 139 VVCPMETIKVKFI--HDQTS---PNPKYRGFFHGVREIVREQGLKGTYQG-LTATVLKQG 192

Query: 92  YG-AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQG 150
              A++F     L       +        +  V G +A   +     P+DV++TR     
Sbjct: 193 SNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE 252

Query: 151 EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHL 202
             K  NT    +  + + EG + FYKG  P L  +     + F  Y  +  L
Sbjct: 253 AHKYRNTWDCGLQIL-KKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKL 303


>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
          Length = 303

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 78/281 (27%), Positives = 125/281 (44%), Gaps = 31/281 (11%)

Query: 16  FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGP 75
           F    AG V+G++      PFD +K+R Q+Q      S    +Y G L   + I+++E  
Sbjct: 5   FLAGCAGGVAGVLVG---HPFDTVKVRLQVQ------SVEKPQYRGTLHCFKSIIKQESV 55

Query: 76  TAFWKG-HVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
              +KG   P   L+     V  +    L  L H   +         F+ G  A  +  +
Sbjct: 56  LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQ-------FLAGAAAGAIQCV 108

Query: 135 TVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
              P+++ +TR   Q  G  + Y      +  +Y  EG +   +G+  TL+   P  G+ 
Sbjct: 109 ICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVY 168

Query: 193 FSCYSSLKHLYKWAIPAE-GKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
           F  Y +L      A+  E G +    + LL G  +G++S   TYP+D+ K RLQ  G   
Sbjct: 169 FLTYDALTR----ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRG 224

Query: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292
           A        RY+G++DC  Q  + EG   F +GL+ +LL+A
Sbjct: 225 A-------PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 10/178 (5%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG+ +G +   +  P ++ K R QLQ      + P+  Y G L    QI   EG     
Sbjct: 97  LAGAAAGAIQCVICCPMELAKTRLQLQD-----AGPARTYKGSLDCLAQIYGHEGLRGVN 151

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
           +G V   +       V FL+++ LT  +      D        + GG +  ++ L+ +PV
Sbjct: 152 RGMVSTLLRETPSFGVYFLTYDALTRALGC-EPGDRLLVPKLLLAGGTSGIVSWLSTYPV 210

Query: 140 DVLRTRFAA---QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
           DV+++R  A   +G P+ Y  +   V   YR+EG +VF +GLA TL+  FP     F+
Sbjct: 211 DVVKSRLQADGLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFA 267



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%)

Query: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQG-EPKVYNTLRHAVGTMYRSEGPQVFYKG 177
           ++ F+ G        L  HP D ++ R   Q  E   Y    H   ++ + E     YKG
Sbjct: 2   ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61

Query: 178 LAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPL 237
           L   L+ +     L F    +         P        L   L G+ AG I   +  P+
Sbjct: 62  LGSPLMGLTFINALVFGVQGNTLRALGHDSP--------LNQFLAGAAAGAIQCVICCPM 113

Query: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
           +L K RLQ+          G  R YKG +DC  Q+   EG  G  +G+  +LL+   S G
Sbjct: 114 ELAKTRLQLQDA-------GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFG 166

Query: 298 FMFFSYEFFCNVFHC 312
             F +Y+       C
Sbjct: 167 VYFLTYDALTRALGC 181


>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
          Length = 291

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 70/291 (24%), Positives = 125/291 (42%), Gaps = 22/291 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           V G ++ +       P D+ K R Q+Q +         +Y G+L A  +I +EEG  A +
Sbjct: 10  VYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALY 69

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTEL-VHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
            G  PA +    YG ++  +++ L  L + R    +     ++ +CG L+  +++   +P
Sbjct: 70  SGIAPAMLRQASYGTIKIGTYQSLKRLFIERP---EDETLPINVICGILSGVISSTIANP 126

Query: 139 VDVLRTRFAAQGEPKVYNTLRHAV----GTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
            DVL+ R  AQ      NT++  +      +Y+ EG +  +KG++ T        G++  
Sbjct: 127 TDVLKIRMQAQS-----NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181

Query: 195 CYS-SLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHAR 253
            Y  + KHL    +  +      L +  CG    + S     P+D+ + R+         
Sbjct: 182 VYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASN----PVDVVRTRM----MNQRV 233

Query: 254 AAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
              G+   Y G +DC  Q  + EG    +KG  P+ L+        F +YE
Sbjct: 234 LRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYE 284



 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 23/184 (12%)

Query: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPK-------VYNTLRHAVGTMYRSEGPQVF 174
           FV GGLA+  A     P+D+ +TR   QG+          Y  + HA+  + R EG +  
Sbjct: 9   FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68

Query: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQ-NLLCGSGAGVISKTL 233
           Y G+AP ++    Y  ++   Y SLK L+      E  ++E L  N++CG  +GVIS T+
Sbjct: 69  YSGIAPAMLRQASYGTIKIGTYQSLKRLF-----IERPEDETLPINVICGILSGVISSTI 123

Query: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
             P D+ K R+Q      +    G      G++     + Q+EG  G +KG+S +  +AA
Sbjct: 124 ANPTDVLKIRMQA----QSNTIQG------GMIGNFMNIYQQEGTRGLWKGVSLTAQRAA 173

Query: 294 LSTG 297
           +  G
Sbjct: 174 IVVG 177



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 22/192 (11%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           + G +SG+++  + +P DV+KIR Q Q   +          G++     I Q+EG    W
Sbjct: 111 ICGILSGVISSTIANPTDVLKIRMQAQSNTIQG--------GMIGNFMNIYQQEGTRGLW 162

Query: 80  KG-HVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDA--REFSVHFVCGGLAACMATLT 135
           KG  + AQ  +I  G V+   +++  + L+  G + D     F   F CG LA  +A+  
Sbjct: 163 KGVSLTAQRAAIVVG-VELPVYDITKKHLILSGLMGDTVYTHFLSSFTCG-LAGALAS-- 218

Query: 136 VHPVDVLRTRFAAQ-----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAG 190
            +PVDV+RTR   Q     G    Y      +   +++EG    YKG  P  + + P+  
Sbjct: 219 -NPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNI 277

Query: 191 LQFSCYSSLKHL 202
           + F  Y  LK L
Sbjct: 278 IFFVTYEQLKKL 289



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 23/78 (29%), Positives = 47/78 (60%), Gaps = 2/78 (2%)

Query: 216 NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQK 275
           N +  + G  A + ++  T+P+DL K RLQ+ G +   A F ++ RY+G++    ++ ++
Sbjct: 5   NWKPFVYGGLASITAECGTFPIDLTKTRLQIQG-QTNDAKFKEI-RYRGMLHALVRIGRE 62

Query: 276 EGALGFFKGLSPSLLKAA 293
           EG    + G++P++L+ A
Sbjct: 63  EGLKALYSGIAPAMLRQA 80


>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
          Length = 298

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 67/293 (22%), Positives = 133/293 (45%), Gaps = 21/293 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           +AG V+  +++  ++P + +K+  Q+QH    +     +Y GI+    +I +E+G  +FW
Sbjct: 13  LAGGVAAAISKTAVAPIERVKLLLQVQHAS-KQITADKQYKGIIDCVVRIPKEQGVLSFW 71

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV----CGGLAACMATLT 135
           +G++   I      A+ F +F+   + +  G V    +F ++F      GG A   +   
Sbjct: 72  RGNLANVIRYFPTQALNF-AFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCF 130

Query: 136 VHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191
           V+P+D  RTR AA     G  + +  L   +  +Y+S+G +  Y+G   ++  I  Y   
Sbjct: 131 VYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAA 190

Query: 192 QFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
            F  Y + K +       + K    + + +       ++   +YP D  ++R+ +     
Sbjct: 191 YFGIYDTAKGMLP-----DPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRK 245

Query: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
                G    Y G +DC +++ + EG   FFKG   ++L+  +   F+   Y+
Sbjct: 246 -----GTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYD 292



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 46/185 (24%), Positives = 81/185 (43%), Gaps = 18/185 (9%)

Query: 115 AREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ------GEPKVYNTLRHAVGTMYRS 168
           A  F+  F+ GG+AA ++   V P++ ++     Q         K Y  +   V  + + 
Sbjct: 5   AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKE 64

Query: 169 EGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNE----NLQNLLCGS 224
           +G   F++G    +I  FP   L F+     K ++   +    K+ +       NL  G 
Sbjct: 65  QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGV---DKRTQFWLYFAGNLASGG 121

Query: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
            AG  S    YPLD  + RL     +  +A  G  R ++GL DC  ++ + +G  G ++G
Sbjct: 122 AAGATSLCFVYPLDFARTRLAA---DVGKA--GAEREFRGLGDCLVKIYKSDGIKGLYQG 176

Query: 285 LSPSL 289
            + S+
Sbjct: 177 FNVSV 181


>gi|6031192 solute carrier family 25 member 3 isoform a precursor
           [Homo sapiens]
          Length = 362

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 78/294 (26%), Positives = 130/294 (44%), Gaps = 38/294 (12%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           + G +S   T   + P D++K R Q+        DP  KY GI       L+E+G     
Sbjct: 70  LGGIISCGTTHTALVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLA 120

Query: 80  KGHVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLT 135
           KG  P  +     G  +F  +E+     + ++   + Y  R  S++      A   A + 
Sbjct: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIA 179

Query: 136 VHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSC 195
           + P++  + R   Q +P   NTLR A   MY+ EG + FYKG+AP  +   PY  ++F+C
Sbjct: 180 LAPMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237

Query: 196 YS-SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFE 250
           +  +++ LYK+ +P   +E  K E L    + G  AGV    +++P D            
Sbjct: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------------ 285

Query: 251 HARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
              +    + + KG    A  VL++ G  G +KGL   ++     T   +F Y+
Sbjct: 286 ---SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 334



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 14  TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
           T   +A + S       AL +P +  K+R Q Q             + +  A+ ++ +EE
Sbjct: 162 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 211

Query: 74  GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
           G  AF+KG  P  +  I Y  ++F  FE   E +++  V   R       +  V FV G 
Sbjct: 212 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 271

Query: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
           +A     +  HP D             V + L    G+    + +  G +  +KGL   +
Sbjct: 272 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 319

Query: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
           I I     LQ+  Y S+K  ++   P   +  E+L+  L
Sbjct: 320 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 358


>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
          Length = 312

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 63/196 (32%), Positives = 94/196 (47%), Gaps = 8/196 (4%)

Query: 8   PDGRNNTKFQVAV-AGSVSGLVTRALISPFDVIKIRFQLQ-HERLSRSDPSAKYHGILQA 65
           P G +N+     + AG  +G +      P DV+K+RFQ   H   SRSD   KY G + A
Sbjct: 108 PKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSD--RKYSGTMDA 165

Query: 66  SRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVC 124
            R I +EEG    WKG +P  + +      + +++++L E L+    + D   F  HFV 
Sbjct: 166 YRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTD--NFPCHFVS 223

Query: 125 GGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
              A   AT+   PVDV++TR+     P  Y +    +  M   EGP  FYKG  P+ + 
Sbjct: 224 AFGAGFCATVVASPVDVVKTRYM-NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLR 282

Query: 185 IFPYAGLQFSCYSSLK 200
           +  +  + F  Y  LK
Sbjct: 283 LGSWNVVMFVTYEQLK 298



 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 56/185 (30%), Positives = 86/185 (46%), Gaps = 16/185 (8%)

Query: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLR--------HAVGTMYRSEG 170
           +V F+  G AAC A L   P+D  + R   QGE +   T R          + TM R+EG
Sbjct: 14  AVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEG 73

Query: 171 PQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVI 229
           P   Y GL   L     +A ++   Y S+K +Y      +G  N +L   +L G   G +
Sbjct: 74  PCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVY----TPKGADNSSLTTRILAGCTTGAM 129

Query: 230 SKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSL 289
           + T   P D+ K R Q     H   +    R+Y G MD  + + ++EG  G +KG  P++
Sbjct: 130 AVTCAQPTDVVKVRFQAS--IHLGPSRSD-RKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186

Query: 290 LKAAL 294
           ++ A+
Sbjct: 187 MRNAI 191



 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 33/283 (11%)

Query: 35  PFDVIKIRFQLQHERLS-RSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
           P D  K+R Q+Q E  + ++    +Y G+L     +++ EGP + + G V      + + 
Sbjct: 33  PLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFA 92

Query: 94  AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ---- 149
           +++   ++ + + V+     D    +   + G     MA     P DV++ RF A     
Sbjct: 93  SIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLG 151

Query: 150 --GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLK------H 201
                + Y+    A  T+ R EG +  +KG  P ++        +   Y  LK      H
Sbjct: 152 PSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYH 211

Query: 202 LYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
           L     P          + +   GAG  +  +  P+D+ K R       +  +  GQ   
Sbjct: 212 LLTDNFPC---------HFVSAFGAGFCATVVASPVDVVKTR-------YMNSPPGQ--- 252

Query: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
           Y   +DC  +++ +EG   F+KG +PS L+       MF +YE
Sbjct: 253 YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYE 295


>gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]
          Length = 301

 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 74/311 (23%), Positives = 131/311 (42%), Gaps = 39/311 (12%)

Query: 11  RNNTKFQVAV---AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASR 67
           ++N   Q A+   AG+  G        PFD +K++ Q   +          Y G+     
Sbjct: 2   KSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDL---------YRGLTDCCL 52

Query: 68  QILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR---EFSVHFVC 124
           +   + G   F+KG  PA I +I   +V F+ +    ++V + +  D +       +   
Sbjct: 53  KTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAA 112

Query: 125 GGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVFYKG 177
           G  A+  A L + P ++++ R     E        K  NT+   + ++ R +GP  FY G
Sbjct: 113 GSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHG 172

Query: 178 LAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQN---LLCGSGAGVISKTLT 234
           L+ TL+   P     F  Y   +  +     A G+  + L     +L G   G+      
Sbjct: 173 LSSTLLREVPGYFFFFGGYELSRSFF-----ASGRSKDELGPVPLMLSGGVGGICLWLAV 227

Query: 235 YPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAAL 294
           YP+D  K R+QV      +A F  +R +         V++ EG    + GL P++++A  
Sbjct: 228 YPVDCIKSRIQVLSMSGKQAGF--IRTFIN-------VVKNEGITALYSGLKPTMIRAFP 278

Query: 295 STGFMFFSYEF 305
           + G +F +YE+
Sbjct: 279 ANGALFLAYEY 289



 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 54/198 (27%), Positives = 86/198 (43%), Gaps = 7/198 (3%)

Query: 115 AREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVF 174
           A + ++    G        LT  P D ++ +   Q  P +Y  L       Y   G + F
Sbjct: 6   AIQAAIDLTAGAAGGTACVLTGQPFDTMKVKM--QTFPDLYRGLTDCCLKTYSQVGFRGF 63

Query: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGK-KNENLQNLLCGSGAGVISKTL 233
           YKG +P LIA      + F CY   + + +     + + K  +LQN   GS A   +  +
Sbjct: 64  YKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALV 123

Query: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLM-DCAKQVLQKEGALGFFKGLSPSLLKA 292
             P +L K RLQ     +     G++ + +  +    K +L+K+G LGF+ GLS +LL+ 
Sbjct: 124 LCPTELVKCRLQT---MYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLRE 180

Query: 293 ALSTGFMFFSYEFFCNVF 310
                F F  YE   + F
Sbjct: 181 VPGYFFFFGGYELSRSFF 198



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 42/186 (22%), Positives = 73/186 (39%)

Query: 17  QVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPT 76
           Q A AGS +      ++ P +++K R Q  +E  +    +   + +    + IL+++GP 
Sbjct: 108 QNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPL 167

Query: 77  AFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTV 136
            F+ G     +  +      F  +E+       G   D        + GG+      L V
Sbjct: 168 GFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAV 227

Query: 137 HPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY 196
           +PVD +++R                   + ++EG    Y GL PT+I  FP  G  F  Y
Sbjct: 228 YPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAY 287

Query: 197 SSLKHL 202
              + L
Sbjct: 288 EYSRKL 293



 Score = 35.8 bits (81), Expect = 0.052
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 7/88 (7%)

Query: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
           ++G V G+     + P D IK R Q+          S K  G ++    +++ EG TA +
Sbjct: 214 LSGGVGGICLWLAVYPVDCIKSRIQVL-------SMSGKQAGFIRTFINVVKNEGITALY 266

Query: 80  KGHVPAQILSIGYGAVQFLSFEMLTELV 107
            G  P  I +       FL++E   +L+
Sbjct: 267 SGLKPTMIRAFPANGALFLAYEYSRKLM 294


>gi|4505775 solute carrier family 25 member 3 isoform b precursor
           [Homo sapiens]
          Length = 361

 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)

Query: 22  GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81
           G +S  +T   + P D++K R Q+        DP  KY GI       L+E+G     KG
Sbjct: 71  GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121

Query: 82  HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
             P  +     G  +F  +E+     + ++   + Y  R  S++      A   A + + 
Sbjct: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180

Query: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197
           P++  + R   Q +P   NTLR A   MY+ EG + FYKG+AP  +   PY  ++F+C+ 
Sbjct: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238

Query: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
            +++ LYK+ +P   +E  K E L    + G  AGV    +++P D              
Sbjct: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284

Query: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
            +    + + KG    A  VL++ G  G +KGL   ++     T   +F Y+
Sbjct: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)

Query: 14  TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
           T   +A + S       AL +P +  K+R Q Q             + +  A+ ++ +EE
Sbjct: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210

Query: 74  GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
           G  AF+KG  P  +  I Y  ++F  FE   E +++  V   R       +  V FV G 
Sbjct: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270

Query: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
           +A     +  HP D             V + L    G+    + +  G +  +KGL   +
Sbjct: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318

Query: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
           I I     LQ+  Y S+K  ++   P   +  E+L+  L
Sbjct: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,797,645
Number of Sequences: 37866
Number of extensions: 485990
Number of successful extensions: 1731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 993
Number of HSP's gapped (non-prelim): 256
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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