Search of human proteins with 169194717

Search of human proteins with 169194717

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169194717 PREDICTED: similar to Na+/H+ exchanger domain
containing 1 [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169194717 PREDICTED: similar to Na+/H+ exchanger domain conta...   539   e-154
gi|154937338 Na+/H+ exchanger domain containing 1 isoform 2 [Hom...   473   e-133
gi|66793392 Na+/H+ exchanger domain containing 1 isoform 1 [Homo...   473   e-133
gi|47271479 Na+/H+ exchanger domain containing 2 [Homo sapiens]       313   1e-85
gi|169194736 PREDICTED: similar to hCG1988827 [Homo sapiens]           87   2e-17
gi|89030918 PREDICTED: similar to hCG1988827 [Homo sapiens]            87   2e-17
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    32   0.45 
gi|223278415 taste receptor, type 2, member 38 [Homo sapiens]          30   1.7  
gi|28178838 isocitrate dehydrogenase 3 (NAD+) gamma isoform b pr...    29   5.0  
gi|4758582 isocitrate dehydrogenase 3 (NAD+) gamma isoform a pre...    29   5.0  
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]              28   6.5  
gi|8394402 taste receptor T2R4 [Homo sapiens]                          28   6.5  

>gi|169194717 PREDICTED: similar to Na+/H+ exchanger domain
           containing 1 [Homo sapiens]
          Length = 271

 Score =  539 bits (1389), Expect = e-154
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV 60
           MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV
Sbjct: 1   MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV 60

Query: 61  PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA 120
           PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA
Sbjct: 61  PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA 120

Query: 121 AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD 180
           AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD
Sbjct: 121 AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD 180

Query: 181 ILAITGFNTCLSIVFFSGGMLNNAIASIRNKKLTLKRGFLVLTTCVSAVLSSQRIGLHGS 240
           ILAITGFNTCLSIVFFSGGMLNNAIASIRNKKLTLKRGFLVLTTCVSAVLSSQRIGLHGS
Sbjct: 181 ILAITGFNTCLSIVFFSGGMLNNAIASIRNKKLTLKRGFLVLTTCVSAVLSSQRIGLHGS 240

Query: 241 GGLCTLVLSFIAGTKWSQEKVNIFNMLYFKS 271
           GGLCTLVLSFIAGTKWSQEKVNIFNMLYFKS
Sbjct: 241 GGLCTLVLSFIAGTKWSQEKVNIFNMLYFKS 271


>gi|154937338 Na+/H+ exchanger domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 475

 Score =  473 bits (1216), Expect = e-133
 Identities = 246/286 (86%), Positives = 249/286 (87%), Gaps = 23/286 (8%)

Query: 1   MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV 60
           MTWSILGSEALPGGNLFGL IIFYSAIIGGK LQLIRIPLVPP PPLLGMLLAGFTIRNV
Sbjct: 80  MTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNV 139

Query: 61  PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA 120
           PFINEHVHVPN WSSILRSIAL IILIRAGLGLDPQA RHLKVVCFRLAVGPCLMEASAA
Sbjct: 140 PFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAA 199

Query: 121 AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD 180
           AVFSHFIMKFPWQWA LLGFVLGAVSP VVV YMMVLQENGYGVEE IPTLLMAASSMDD
Sbjct: 200 AVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDD 259

Query: 181 ILAITGFNTCLSIVFFSGGMLNNAIASIRN-----------------------KKLTLKR 217
           ILAITGFNTCLSIVF SGG+LNNAIASIRN                       KKLTLKR
Sbjct: 260 ILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKR 319

Query: 218 GFLVLTTCVSAVLSSQRIGLHGSGGLCTLVLSFIAGTKWSQEKVNI 263
           GFLVLT CVSAVL SQRIGLHGSGGLCTLVLSFIAGTKWSQEK+ +
Sbjct: 320 GFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQEKMKV 365


>gi|66793392 Na+/H+ exchanger domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 515

 Score =  473 bits (1216), Expect = e-133
 Identities = 246/286 (86%), Positives = 249/286 (87%), Gaps = 23/286 (8%)

Query: 1   MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV 60
           MTWSILGSEALPGGNLFGL IIFYSAIIGGK LQLIRIPLVPP PPLLGMLLAGFTIRNV
Sbjct: 80  MTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNV 139

Query: 61  PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA 120
           PFINEHVHVPN WSSILRSIAL IILIRAGLGLDPQA RHLKVVCFRLAVGPCLMEASAA
Sbjct: 140 PFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAA 199

Query: 121 AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD 180
           AVFSHFIMKFPWQWA LLGFVLGAVSP VVV YMMVLQENGYGVEE IPTLLMAASSMDD
Sbjct: 200 AVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDD 259

Query: 181 ILAITGFNTCLSIVFFSGGMLNNAIASIRN-----------------------KKLTLKR 217
           ILAITGFNTCLSIVF SGG+LNNAIASIRN                       KKLTLKR
Sbjct: 260 ILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKR 319

Query: 218 GFLVLTTCVSAVLSSQRIGLHGSGGLCTLVLSFIAGTKWSQEKVNI 263
           GFLVLT CVSAVL SQRIGLHGSGGLCTLVLSFIAGTKWSQEK+ +
Sbjct: 320 GFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQEKMKV 365


>gi|47271479 Na+/H+ exchanger domain containing 2 [Homo sapiens]
          Length = 537

 Score =  313 bits (801), Expect = 1e-85
 Identities = 158/286 (55%), Positives = 198/286 (69%), Gaps = 23/286 (8%)

Query: 1   MTWSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNV 60
           + WSI GSE LPGGNLFG++I+FY AIIGGK L LI++P +PP P LLGMLLAGF IRN+
Sbjct: 100 VVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNI 159

Query: 61  PFINEHVHVPNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAA 120
           P IN++V + + WSS LRSIAL+IIL+RAGLGLD +A + LK VC RL++GPC++EA  +
Sbjct: 160 PVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTS 219

Query: 121 AVFSHFIMKFPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDD 180
           A+ +H+++  PWQW  +LGFVLGAVSP VVV  M++LQ  GYGVE+ +PTLLMAA S DD
Sbjct: 220 ALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDD 279

Query: 181 ILAITGFNTCLSIVFFSGGMLNNAIASI-----------------------RNKKLTLKR 217
           ILAITGFNTCL I F +G  + N +  +                          KL  KR
Sbjct: 280 ILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKR 339

Query: 218 GFLVLTTCVSAVLSSQRIGLHGSGGLCTLVLSFIAGTKWSQEKVNI 263
            FLVL   V AV SS   G  GSGGLCTLV++F+AG  W+ EK  +
Sbjct: 340 TFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAEV 385


>gi|169194736 PREDICTED: similar to hCG1988827 [Homo sapiens]
          Length = 92

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 43/44 (97%), Positives = 43/44 (97%)

Query: 155 MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVFFSG 198
           MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVF SG
Sbjct: 1   MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVFSSG 44


>gi|89030918 PREDICTED: similar to hCG1988827 [Homo sapiens]
          Length = 92

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 43/44 (97%), Positives = 43/44 (97%)

Query: 155 MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVFFSG 198
           MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVF SG
Sbjct: 1   MVLQENGYGVEEDIPTLLMAASSMDDILAITGFNTCLSIVFSSG 44


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
            exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 32.3 bits (72), Expect = 0.45
 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 26/146 (17%)

Query: 142  LGAVSPVVVVLYMMVLQENGYG----VEEDIP--TLLMAASSMDDILAITGFNTCLSIVF 195
            LG++  + +  Y+MV   +  G    + E+I   T+L A +S+ D++         S++ 
Sbjct: 942  LGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLIT--------SVIV 993

Query: 196  FSGGMLNNAIAS-IRNKKLTLKRGFLVLTTCVSAVLSSQRIGLHGSGGLCTLVLSF---- 250
               G+ + A++S + +    +  G  V     S +   Q + +  +G  C +VL F    
Sbjct: 994  ARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLL 1053

Query: 251  -----IAGTKWSQEKVNIFNM--LYF 269
                 IA  KW   K+  F M  LYF
Sbjct: 1054 FVISSIASCKWRMNKILGFTMFLLYF 1079


>gi|223278415 taste receptor, type 2, member 38 [Homo sapiens]
          Length = 333

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 191 LSIVFFSGGMLNNAIASIRNKKLTLKRGFLVLTTCVSAVLSSQRIGLHG 239
           +S++ F+ G L NA   + N    +KR  L  + CV   LS  R+ LHG
Sbjct: 21  ISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHG 69


>gi|28178838 isocitrate dehydrogenase 3 (NAD+) gamma isoform b
           precursor [Homo sapiens]
          Length = 380

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 2/90 (2%)

Query: 3   WSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNVPF 62
           W +LG+  +P  N+F    I  SA  GG++  +  IP     P L+  + + F    VP 
Sbjct: 26  WEVLGAHEVPSRNIFSEQTIPPSAKYGGRH-TVTMIPGDGIGPELMLHVKSVFRHACVPV 84

Query: 63  INEHVHV-PNAWSSILRSIALNIILIRAGL 91
             E VHV  NA    +R+  + I   R  L
Sbjct: 85  DFEEVHVSSNADEEDIRNAIMAIRRNRVAL 114


>gi|4758582 isocitrate dehydrogenase 3 (NAD+) gamma isoform a
           precursor [Homo sapiens]
          Length = 393

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 2/90 (2%)

Query: 3   WSILGSEALPGGNLFGLLIIFYSAIIGGKNLQLIRIPLVPPFPPLLGMLLAGFTIRNVPF 62
           W +LG+  +P  N+F    I  SA  GG++  +  IP     P L+  + + F    VP 
Sbjct: 26  WEVLGAHEVPSRNIFSEQTIPPSAKYGGRH-TVTMIPGDGIGPELMLHVKSVFRHACVPV 84

Query: 63  INEHVHV-PNAWSSILRSIALNIILIRAGL 91
             E VHV  NA    +R+  + I   R  L
Sbjct: 85  DFEEVHVSSNADEEDIRNAIMAIRRNRVAL 114


>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
          Length = 2459

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 26/116 (22%), Positives = 46/116 (39%), Gaps = 21/116 (18%)

Query: 70   PNAWSSILRSIALNIILIRAGLGLDPQAWRHLKVVCFRLAVGPCLMEASAAAVFSHFIMK 129
            P++ +  LR +      ++ GLG+ P  W        +++  P                 
Sbjct: 1776 PHSHAQALRQLQT----LKGGLGVQPGTWAPAHASALQVSKPP---------------QG 1816

Query: 130  FPWQWAILLGFVLGAVSPVVVVLYMMVLQENGYGVEEDIPTLLMAASSMDDILAIT 185
             PW W IL+G++L A +  V   + M L    YG    +  L+  A S  + + +T
Sbjct: 1817 LPW-WCILVGWLLVAATSGVAAFFTM-LYGLHYGRASSLRWLISMAVSFVESMFVT 1870


>gi|8394402 taste receptor T2R4 [Homo sapiens]
          Length = 299

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 8/69 (11%)

Query: 164 VEEDIPTLLMAASSMDDILAITGFNTCLSIVFFSGGMLNNAIASIRNKKLTLKRGFLVLT 223
           +   IP LL+A       + I+ F TCL I           + +  N    +  G  +L+
Sbjct: 125 ISPKIPRLLLAC------VLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEG--ILS 176

Query: 224 TCVSAVLSS 232
             VS VLSS
Sbjct: 177 LVVSLVLSS 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.142    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,003,999
Number of Sequences: 37866
Number of extensions: 405003
Number of successful extensions: 963
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 952
Number of HSP's gapped (non-prelim): 12
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.