Search of human proteins with 16753215

Search of human proteins with 16753215

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16753215 profilin 2 isoform a [Homo sapiens]
         (140 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16753215 profilin 2 isoform a [Homo sapiens]                       293   3e-80
gi|4505751 profilin 2 isoform b [Homo sapiens]                        273   3e-74
gi|4826898 profilin 1 [Homo sapiens]                                  185   1e-47
gi|71274140 profilin 3 [Homo sapiens]                                 112   1e-25
gi|239741295 PREDICTED: similar to PDE4DIP protein [Homo sapiens]      69   1e-12
gi|14591902 RecQ protein-like [Homo sapiens]                           32   0.22 
gi|14591904 RecQ protein-like [Homo sapiens]                           32   0.22 
gi|7661728 roadblock domain-containing protein 3 isoform 1 [Homo...    26   9.3  
gi|110349792 growth differentiation factor 1 [Homo sapiens]            26   9.3  
gi|139394648 DNA polymerase theta [Homo sapiens]                       26   9.3  

>gi|16753215 profilin 2 isoform a [Homo sapiens]
          Length = 140

 Score =  293 bits (750), Expect = 3e-80
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
           MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
Sbjct: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60

Query: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120
           TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
Sbjct: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120

Query: 121 GGGLNKKAYSMAKYLRDSGF 140
           GGGLNKKAYSMAKYLRDSGF
Sbjct: 121 GGGLNKKAYSMAKYLRDSGF 140


>gi|4505751 profilin 2 isoform b [Homo sapiens]
          Length = 140

 Score =  273 bits (698), Expect = 3e-74
 Identities = 131/138 (94%), Positives = 132/138 (95%)

Query: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
           MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
Sbjct: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60

Query: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120
           TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGR LV VMGKEGVH
Sbjct: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRALVIVMGKEGVH 120

Query: 121 GGGLNKKAYSMAKYLRDS 138
           GG LNKKAY +A YLR S
Sbjct: 121 GGTLNKKAYELALYLRRS 138


>gi|4826898 profilin 1 [Homo sapiens]
          Length = 140

 Score =  185 bits (469), Expect = 1e-47
 Identities = 86/140 (61%), Positives = 106/140 (75%)

Query: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
           MAGW +Y+DNLM DG CQ+AAIVGY D+  VWAA  G  F +ITP E+ ++VGKDR  F+
Sbjct: 1   MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY 60

Query: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120
            NGLTLG +KCSVIRDSL  DG+ +MD+RTKS GG PT+NV V +  + LV +MGKEGVH
Sbjct: 61  VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH 120

Query: 121 GGGLNKKAYSMAKYLRDSGF 140
           GG +NKK Y MA +LR S +
Sbjct: 121 GGLINKKCYEMASHLRRSQY 140


>gi|71274140 profilin 3 [Homo sapiens]
          Length = 137

 Score =  112 bits (279), Expect = 1e-25
 Identities = 57/139 (41%), Positives = 82/139 (58%), Gaps = 3/139 (2%)

Query: 1   MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF 60
           M  W+ Y+  ++ D    + AIVG+ D   VWA+  GG+  +I+P E+ ++ G DR  F 
Sbjct: 1   MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL 60

Query: 61  TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH 120
             GL++G ++C VIRD L  +GD  +D RTK   G     V VGRA R L+ +MG+ GVH
Sbjct: 61  QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH 117

Query: 121 GGGLNKKAYSMAKYLRDSG 139
           GG LNK  + + + LR  G
Sbjct: 118 GGILNKTVHELIRGLRMQG 136


>gi|239741295 PREDICTED: similar to PDE4DIP protein [Homo sapiens]
          Length = 66

 Score = 68.9 bits (167), Expect = 1e-12
 Identities = 33/65 (50%), Positives = 43/65 (66%)

Query: 62  NGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHG 121
           NGLTLG +K +V+ DSL  DG+ T D+  KS  G PT+NV V    + L  +MGKEG+HG
Sbjct: 2   NGLTLGGQKYTVVLDSLLQDGELTTDLCMKSISGAPTFNVIVTMTAKTLGLLMGKEGIHG 61

Query: 122 GGLNK 126
             +NK
Sbjct: 62  NFINK 66


>gi|14591902 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 31.6 bits (70), Expect = 0.22
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 4   WQSYVDNLMCDGCCQEAA-----IVGYCDAKYVWAATAGGVFQSITPIE-IDMIVGK 54
           W S   N MCD CC+++A     I  YC         A  + + +TP++ ID  +GK
Sbjct: 466 WNSEACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGK 522


>gi|14591904 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 31.6 bits (70), Expect = 0.22
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 4   WQSYVDNLMCDGCCQEAA-----IVGYCDAKYVWAATAGGVFQSITPIE-IDMIVGK 54
           W S   N MCD CC+++A     I  YC         A  + + +TP++ ID  +GK
Sbjct: 466 WNSEACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGK 522


>gi|7661728 roadblock domain-containing protein 3 isoform 1 [Homo
           sapiens]
          Length = 125

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 101 VAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRD 137
           VA+ R   +L+ +  KE V  G L  KA ++ +YL +
Sbjct: 81  VAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEE 117


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 11/28 (39%), Positives = 13/28 (46%)

Query: 79  YVDGDCTMDIRTKSQGGEPTYNVAVGRA 106
           Y  G C + +     GG P  N AV RA
Sbjct: 295 YCQGQCALPVALSGSGGPPALNHAVLRA 322


>gi|139394648 DNA polymerase theta [Homo sapiens]
          Length = 2590

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 57  EGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEP----TYNVAVGRAGRVLVF 112
           EG F  GL       S +   + +     + IRT   GG P    TY   VGRAGR  V 
Sbjct: 429 EGAFRQGLIRVLAATSTLSSGVNLPARRVI-IRTPIFGGRPLDILTYKQMVGRAGRKGVD 487

Query: 113 VMGK 116
            +G+
Sbjct: 488 TVGE 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,237,360
Number of Sequences: 37866
Number of extensions: 209709
Number of successful extensions: 293
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 283
Number of HSP's gapped (non-prelim): 10
length of query: 140
length of database: 18,247,518
effective HSP length: 92
effective length of query: 48
effective length of database: 14,763,846
effective search space: 708664608
effective search space used: 708664608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.