Search of human proteins with 166795283

Search of human proteins with 166795283

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
         (463 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          960   0.0  
gi|4503947 glucagon receptor [Homo sapiens]                           415   e-116
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   375   e-104
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     371   e-103
gi|114205383 secretin receptor precursor [Homo sapiens]               300   2e-81
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   284   1e-76
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    260   2e-69
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   244   1e-64
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   243   3e-64
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    236   2e-62
gi|58530851 growth hormone releasing hormone receptor isoform a ...   223   3e-58
gi|4502547 calcitonin receptor [Homo sapiens]                         195   8e-50
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   186   4e-47
gi|5031621 calcitonin receptor-like [Homo sapiens]                    184   1e-46
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   181   2e-45
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   168   8e-42
gi|58530853 growth hormone releasing hormone receptor isoform b ...   167   2e-41
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   165   7e-41
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   152   6e-37
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              85   2e-16
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]            75   1e-13
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]            75   1e-13
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]            75   1e-13
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           74   2e-13
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           74   2e-13
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      73   6e-13
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    72   1e-12
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             71   2e-12
gi|148806925 EGF, latrophilin and seven transmembrane domain con...    71   2e-12
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    70   3e-12

>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  960 bits (2481), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 1   MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL 60
           MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL
Sbjct: 1   MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL 60

Query: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120
           FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW
Sbjct: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120

Query: 121 RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180
           RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH
Sbjct: 121 RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180

Query: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN 240
           LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN
Sbjct: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN 240

Query: 241 YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN 300
           YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN
Sbjct: 241 YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN 300

Query: 301 SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL 360
           SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
Sbjct: 301 SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL 360

Query: 361 GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW 420
           GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW
Sbjct: 361 GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW 420

Query: 421 RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS 463
           RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
Sbjct: 421 RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS 463


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  415 bits (1066), Expect = e-116
 Identities = 214/426 (50%), Positives = 279/426 (65%), Gaps = 24/426 (5%)

Query: 7   PLRLALLLLGMVGRAGPRPQGATVSLWETV-QKWREYRRQCQRSLTEDPPPATDLFCNRT 65
           PL L LLLL        +PQ  +  + + + +KW+ Y  QC  +L+  PPP T+L CNRT
Sbjct: 9   PLLLLLLLLAC------QPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPP-TELVCNRT 61

Query: 66  FDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSE 125
           FD+Y+CWPD    +  N+SCPWYLPW   V    V++ C  +G W++      PWRD S+
Sbjct: 62  FDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQ-PWRDASQ 120

Query: 126 CEESKRGERSSPEEQLLFLY----IIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHL 181
           C+    GE    ++++  +Y    ++YTVGY+LS  AL++A AIL G   LHCTRN IH 
Sbjct: 121 CQMD--GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHA 178

Query: 182 NLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGL-----LSYQDSLSCRLVFLLMQYC 236
           NLFASF+L+A SV + D  L+  YS    Q   D L     LS      CR+  + MQY 
Sbjct: 179 NLFASFVLKASSVLVIDGLLRTRYS----QKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234

Query: 237 VAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGC 296
           + ANY WLLVEG+YL+ LL  + L E+  F LY+ IGWG P+LFVVPW +VK L+E+  C
Sbjct: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294

Query: 297 WTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTL 356
           WT N NM +W I+R P+  AI +NF IFVR++ ++V+KL+A  M  TD K RLAKSTLTL
Sbjct: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354

Query: 357 IPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 416
           IPLLG HEV+FAFV DEHA+GTLR  KLF +L  +SFQGL+VA+LYCF+N EVQ E R+ 
Sbjct: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRR 414

Query: 417 WERWRL 422
           W RWRL
Sbjct: 415 WHRWRL 420


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  375 bits (964), Expect = e-104
 Identities = 195/422 (46%), Positives = 267/422 (63%), Gaps = 15/422 (3%)

Query: 4   APGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCN 63
           APG   L L+LL  +       Q     L ET +KW +Y++ C R L ++P   + +FCN
Sbjct: 47  APGRPFLTLVLLVSI------KQVTGSLLEETTRKWAQYKQACLRDLLKEP---SGIFCN 97

Query: 64  RTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDL 123
            TFD+Y CWP   PG+ V+V CP YLPW S    G  YR C A+G W   +N++  W+D 
Sbjct: 98  GTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDD 156

Query: 124 SECEESKRGERSSPEEQLLF-LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLN 182
           SEC E+   +++     LL  L ++YTVGY+ S  +L +A  +LL  R LHCTRNYIH+N
Sbjct: 157 SECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMN 216

Query: 183 LFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSY--QDSLSCRLVFLLMQYCVAAN 240
           LFASFILR L+V +KD      YS        +G +SY  + S SCR V +L+ Y V AN
Sbjct: 217 LFASFILRTLAVLVKDVVFYNSYSKRPDNE--NGWMSYLSEMSTSCRSVQVLLHYFVGAN 274

Query: 241 YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN 300
           Y WLLVEG+YL+TLL  +VL E+ ++  Y+ +GW  P+LFVVPWG  +   E+ GCWT N
Sbjct: 275 YLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTN 334

Query: 301 SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL 360
            N   W IIR P++  + VNF IF++++ +++SKLKA+ MC  D K RLAKSTL LIPLL
Sbjct: 335 GNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLL 394

Query: 361 GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW 420
           G HE++F+F+ D+   G  + I+LF +L+ +SF G +VA+ Y F N EV+ E RK W R+
Sbjct: 395 GVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRF 454

Query: 421 RL 422
            L
Sbjct: 455 LL 456


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  371 bits (952), Expect = e-103
 Identities = 208/459 (45%), Positives = 270/459 (58%), Gaps = 32/459 (6%)

Query: 8   LRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFD 67
           LRL+L  L ++ RA    +G T    E  Q+W  YRR+CQ +L    PP+  L CN +FD
Sbjct: 11  LRLSLCGL-LLQRAETGSKGQTAG--ELYQRWERYRRECQETLAAAEPPS-GLACNGSFD 66

Query: 68  EYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECE 127
            Y CW    P +    SCPWYLPW   V  G V R C ++G W         WRD ++CE
Sbjct: 67  MYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCE 119

Query: 128 ESKRGERSSPEEQLLF-LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFAS 186
             ++ E    +  +L  L ++YTVGY+LS + L++A  IL  FR LHCTRNYIH+NLF S
Sbjct: 120 NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTS 179

Query: 187 FILRALSVFIKDAALKWMYSTAAQQHQ--WDGLLSYQDSLSCRLVFLLMQYCVAANYYWL 244
           F+LRA ++  +D  L         Q    W+  L+     +CR   ++ QYCV ANY WL
Sbjct: 180 FMLRAAAILSRDRLLPRPGPYLGDQALALWNQALA-----ACRTAQIVTQYCVGANYTWL 234

Query: 245 LVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMN 304
           LVEGVYL++LL     SE+  FR Y+ +GWG P LFV+PW IV+YLYE+  CW RN    
Sbjct: 235 LVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKA 294

Query: 305 YWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHE 364
            W IIR PIL  I +NFLIF+R++ I++SKL+   M   D + RLA+STLTL+PLLG HE
Sbjct: 295 IWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHE 354

Query: 365 VIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRL-- 422
           V+FA V +E ARG LRF KL  E+  +SFQG +V++LYCF+N EVQ E R+ W   RL  
Sbjct: 355 VVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRR 414

Query: 423 ----------EHLHIQRDSSMKPLKCPTS-SLSSGATAG 450
                     E       S   P + PTS  LSSG   G
Sbjct: 415 SLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPG 453


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  300 bits (768), Expect = 2e-81
 Identities = 181/466 (38%), Positives = 255/466 (54%), Gaps = 50/466 (10%)

Query: 10  LALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSL---------TEDPPPATDL 60
           L  LLL ++        GA   L + +Q   E + QC + L         TE P P    
Sbjct: 9   LQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPG--- 65

Query: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120
            C   +D  +CWP   PG  V V CP +L   +S   G ++R CT +G W    + + P 
Sbjct: 66  -CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDG-W----SETFPR 118

Query: 121 RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180
            +L+                LL L ++YTVGY+ S   L++A  IL  FR LHCTRNYIH
Sbjct: 119 PNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIH 178

Query: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDS--LSCRLVFLLMQYCVA 238
           ++LF SFILRALS FIKDA L   +S+          ++Y D+    C+LV +L QYC+ 
Sbjct: 179 MHLFVSFILRALSNFIKDAVL---FSSDD--------VTYCDAHRAGCKLVMVLFQYCIM 227

Query: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWT 298
           ANY WLLVEG+YL+TLLA S  SE+   + +V+ GWG P +FV  W I ++  ED GCW 
Sbjct: 228 ANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWD 287

Query: 299 RNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLTL 356
            N+N + W IIR P++ +I +NF++F+ ++ I++ KL+       ++    RLA+STL L
Sbjct: 288 INANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLL 347

Query: 357 IPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 416
           IPL G H ++FAF  ++        I+LF EL+  SFQGL+VA+LYCF+N EVQLE +K 
Sbjct: 348 IPLFGIHYIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKK 402

Query: 417 WERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGS-SMYTATCQAS 461
           W++W L    +           P +S S+   A        TC+ S
Sbjct: 403 WQQWHLREFPLH----------PVASFSNSTKASHLEQSQGTCRTS 438


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  284 bits (726), Expect = 1e-76
 Identities = 180/459 (39%), Positives = 245/459 (53%), Gaps = 30/459 (6%)

Query: 4   APGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCN 63
           +P P R   +L G +  A     G    L E     +    Q ++ L E       + C+
Sbjct: 5   SPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCS 64

Query: 64  RTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDL 123
           + +D   CWP    G  V ++CP      SS+   +V R CT EG W   +    P    
Sbjct: 65  KMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG-WTHLEPGPYP---- 119

Query: 124 SECEESKRGERSSPEEQLLFLYII---YTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180
             C    +   S  E+Q +F   +   YT+GY LS + L++A+AIL  FR LHCTRNYIH
Sbjct: 120 IACGLDDKAA-SLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIH 178

Query: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN 240
           ++LF SFILRA +VFIKD AL   + +       +G      S+ C+   +  QYCV AN
Sbjct: 179 MHLFISFILRAAAVFIKDLAL---FDSGESDQCSEG------SVGCKAAMVFFQYCVMAN 229

Query: 241 YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN 300
           ++WLLVEG+YLYTLLA S  SE+  F  Y+ IGWGVP  F + W I +  +ED GCW   
Sbjct: 230 FFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-T 288

Query: 301 SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLTLIP 358
            N + W II+ PIL +I VNF++F+ +I I++ KL+   + K+D     RLA+STL LIP
Sbjct: 289 INSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIP 348

Query: 359 LLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWE 418
           L G H ++FAF  D         +K+  EL   SFQG +VAILYCF+N EVQ E R+ W 
Sbjct: 349 LFGVHYIMFAFFPDNFKPE----VKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWR 404

Query: 419 RWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTAT 457
           RW     H+Q      P     S  S+GAT  + +   T
Sbjct: 405 RW-----HLQGVLGWNPKYRHPSGGSNGATCSTQVSMLT 438


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  260 bits (665), Expect = 2e-69
 Identities = 146/379 (38%), Positives = 211/379 (55%), Gaps = 25/379 (6%)

Query: 62  CNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWR 121
           C   +D   CWP G PG  V V CP Y+   +   +GH YR C   G W      +  W 
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNH--KGHAYRRCDRNGSWELVPGHNRTWA 165

Query: 122 DLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHL 181
           + SEC +    E +   E    L +IYTVGY++S ++L +A  IL  FR LHCTRNYIH+
Sbjct: 166 NYSECVKFLTNE-TREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHM 224

Query: 182 NLFASFILRALSVFIKDAALKWMYSTA----AQQHQWDGLLSYQDS-----------LSC 226
           +LF SF+LRA+S+F+KDA L   YS A    A++   + L +   +             C
Sbjct: 225 HLFLSFMLRAVSIFVKDAVL---YSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGC 281

Query: 227 RLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGI 286
           R+      Y +A NYYW+LVEG+YL++L+  +  SE+     +   GWG+P +FV  W  
Sbjct: 282 RVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVS 341

Query: 287 VKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK 346
           V+    + GCW  +S    W II++PIL +I +NF++F+ ++ ++ +KL+     + D +
Sbjct: 342 VRATLANTGCWDLSSGNKKW-IIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTR 400

Query: 347 C---RLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYC 403
               +L KSTL L+PL G H ++F         GTL  +++  E+ F SFQG  VAI+YC
Sbjct: 401 QQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYC 460

Query: 404 FVNNEVQLEFRKSWERWRL 422
           F N EVQ E +KSW RW L
Sbjct: 461 FCNGEVQAEIKKSWSRWTL 479


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  244 bits (623), Expect = 1e-64
 Identities = 145/363 (39%), Positives = 205/363 (56%), Gaps = 31/363 (8%)

Query: 62  CNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWR 121
           C+  +D   CW     G  V V CP       S   G++ + CT++G           W 
Sbjct: 52  CSGVWDNITCWRPANVGETVTVPCPKVFSNFYS-KAGNISKNCTSDG-----------WS 99

Query: 122 DLSECEESKRGERSSPEEQLLFLYI----IYTVGYALSFSALVIASAILLGFRHLHCTRN 177
           +         G     +E  +  YI    IYT+GY++S  +L   S IL  FR LHCTRN
Sbjct: 100 ETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRN 159

Query: 178 YIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCV 237
           YIHLNLF SFILRA+SV +KD  L   YS++   H  D   S+   + C+L  + +QYC+
Sbjct: 160 YIHLNLFLSFILRAISVLVKDDVL---YSSSGTLHCPDQPSSW---VGCKLSLVFLQYCI 213

Query: 238 AANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW 297
            AN++WLLVEG+YL+TLL  ++L  +  F  Y+ IGWG+P + +  W   +   ED GCW
Sbjct: 214 MANFFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCW 272

Query: 298 TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLT 355
             N +   W +IR+PIL +I VNF++F+ +I I++ KL +  +   D     RLAKSTL 
Sbjct: 273 DTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLL 332

Query: 356 LIPLLGTHEVIFA-FVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFR 414
           LIPL G H ++FA F +   ++  + F     EL   SFQGL+VA+LYCF+N+EVQ E +
Sbjct: 333 LIPLFGVHYMVFAVFPISISSKYQILF-----ELCLGSFQGLVVAVLYCFLNSEVQCELK 387

Query: 415 KSW 417
           + W
Sbjct: 388 RKW 390


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  243 bits (620), Expect = 3e-64
 Identities = 146/416 (35%), Positives = 206/416 (49%), Gaps = 47/416 (11%)

Query: 62  CNRTFDEYACWPDGEPGSFVNVSCPWYLP-------WASSV---------------PQGH 99
           C   +D   CW     G  V VSCP           W +                   G 
Sbjct: 54  CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113

Query: 100 VYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSAL 159
           V R CT +G W +            E E     E    +   L +  +YTVGY+ S   L
Sbjct: 114 VSRNCTEDG-WSEPFPHYFDACGFDEYES----ETGDQDYYYLSVKALYTVGYSTSLVTL 168

Query: 160 VIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLS 219
             A  IL  FR LHCTRN+IH+NLF SF+LRA+SVFIKD  L   Y+     H       
Sbjct: 169 TTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL---YAEQDSNH------C 219

Query: 220 YQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLL 279
           +  ++ C+ V +   YCV +NY+WL +EG+YL+TLL  +   E+  F  Y  IGWG P +
Sbjct: 220 FISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTV 279

Query: 280 FVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANL 339
            V  W  ++  ++D GCW  N +   W +I+ P++ +I VNF++F+ +I I+V KL++  
Sbjct: 280 CVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPD 339

Query: 340 M--CKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLM 397
           M   ++ I  RLA+STL LIPL G H  +FAF  +  ++      +L  EL   SFQG +
Sbjct: 340 MGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRE----RLVFELGLGSFQGFV 395

Query: 398 VAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSM 453
           VA+LYCF+N EVQ E ++ W  W++            P     S  SSG   G+ +
Sbjct: 396 VAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHP-----SLASSGVNGGTQL 446


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  236 bits (603), Expect = 2e-62
 Identities = 144/439 (32%), Positives = 229/439 (52%), Gaps = 23/439 (5%)

Query: 1   MAGAPGPLRL-ALLLLG--MVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPA 57
           MAG    L +   L+LG  ++ RA     G T+++ E +    + + QC+ ++T      
Sbjct: 1   MAGLGASLHVWGWLMLGSCLLARAQLDSDG-TITIEEQIVLVLKAKVQCELNITAQLQEG 59

Query: 58  TDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSS 117
               C   +D   CWP G  G    V CP Y+   +   +G  +R C   G W    + +
Sbjct: 60  EGN-CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNH--KGVAFRHCNPNGTWDFMHSLN 116

Query: 118 LPWRDLSECEESKRGERSSPEEQLLF-LYIIYTVGYALSFSALVIASAILLGFRHLHCTR 176
             W + S+C    + + S  +++    LY++YTVGY++SF +L +A  I+  FR LHCTR
Sbjct: 117 KTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTR 176

Query: 177 NYIHLNLFASFILRALSVFIKD------AALKWMYSTAAQQHQWDGL----LSYQDSLSC 226
           NYIH++LF SF+LRA S+F+KD        +K + S   Q    + +    +     + C
Sbjct: 177 NYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGC 236

Query: 227 RLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGI 286
           ++  ++  Y +A NYYW+LVEG+YL+ L+  +  S+      ++ IGWG P  FV  W +
Sbjct: 237 KIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAV 296

Query: 287 VKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK 346
            +    D  CW  ++    W I + PIL AIG+NF++F+  + ++ +K+        D +
Sbjct: 297 ARATLADARCWELSAGDIKW-IYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTR 355

Query: 347 ---CRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYC 403
               +LAKSTL L+ + G H ++F   +     G    I++  EL F SFQG  V+I+YC
Sbjct: 356 KQYRKLAKSTLVLVLVFGVHYIVFV-CLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYC 414

Query: 404 FVNNEVQLEFRKSWERWRL 422
           + N EVQ E +K W RW L
Sbjct: 415 YCNGEVQAEVKKMWSRWNL 433


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  223 bits (568), Expect = 3e-58
 Identities = 145/385 (37%), Positives = 199/385 (51%), Gaps = 27/385 (7%)

Query: 36  VQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSV 95
           + + RE    C ++  E   P T L C  T+D   CWP    G +V + CP +    SS 
Sbjct: 31  ITQLREDESACLQAAEE--MPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSS- 87

Query: 96  PQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALS 155
             G V R CT  G W      S P+              +  E     + IIYTVG+++S
Sbjct: 88  ESGAVKRDCTITG-W------SEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSIS 140

Query: 156 FSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWD 215
             AL +A  IL+  R LHC RNY+H  LF +FIL+A +VF+KDAAL   +S       + 
Sbjct: 141 IVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAAL--FHSDDTDHCSFS 198

Query: 216 GLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWG 275
            +L       C++      +    N+ WLL E VYL  LLA +  S +  F   V  GWG
Sbjct: 199 TVL-------CKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWG 251

Query: 276 VPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKL 335
           +P+LF   W   K  +ED  CW  +    YW II+ PI+ ++GVNF +F+ +I I+V KL
Sbjct: 252 LPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL 311

Query: 336 ---KANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTS 392
              + +L  ++    RL+KSTL LIPL G H +IF F+ D    G    I+L  EL   S
Sbjct: 312 EPAQGSLHTQSQY-WRLSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGS 366

Query: 393 FQGLMVAILYCFVNNEVQLEFRKSW 417
           FQG +VAILYCF+N EV+ E  + W
Sbjct: 367 FQGFIVAILYCFLNQEVRTEISRKW 391


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  195 bits (495), Expect = 8e-50
 Identities = 109/365 (29%), Positives = 188/365 (51%), Gaps = 25/365 (6%)

Query: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120
           +CNRT+D + CW D   G      CP Y P     P   V ++C  +G+W +   ++  W
Sbjct: 71  YCNRTWDGWLCWDDTPAGVLSYQFCPDYFP--DFDPSEKVTKYCDEKGVWFKHPENNRTW 128

Query: 121 RDLSECEESKRGERSSPEE--QLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178
            + + C         +PE+      LY +  VG++LS   LVI+  I + FR L C R  
Sbjct: 129 SNYTMCNAF------TPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVT 182

Query: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVA 238
           +H N+F ++IL ++ + I    +             +G L  +D +SC+++    QY +A
Sbjct: 183 LHKNMFLTYILNSMIIIIHLVEVVP-----------NGELVRRDPVSCKILHFFHQYMMA 231

Query: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWT 298
            NY+W+L EG+YL+TL+  +V +E+   R Y  +GWG PL+      I + +Y ++ CW 
Sbjct: 232 CNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWL 291

Query: 299 RNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIP 358
            +   +   II  P++ A+ VNF   + ++ ++V+K++     ++ +  +  K+T+ L+P
Sbjct: 292 -SVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP 350

Query: 359 LLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWE 418
           LLG   V+F +       G    I  +   S   FQG  VA +YCF NNEVQ   ++ W 
Sbjct: 351 LLGIQFVVFPWRPSNKMLGK---IYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWA 407

Query: 419 RWRLE 423
           +++++
Sbjct: 408 QFKIQ 412


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  186 bits (472), Expect = 4e-47
 Identities = 116/385 (30%), Positives = 182/385 (47%), Gaps = 31/385 (8%)

Query: 61  FCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLP 119
           +CN T D+   CWP    G+ V   CP Y          + YR C   G W  K N    
Sbjct: 39  YCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKIN---- 94

Query: 120 WRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYI 179
               S+CE     ++   +       ++  +G+ +S +ALV A  + L  R + C RN I
Sbjct: 95  ---YSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVI 151

Query: 180 HLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAA 239
           H NL  +FILR +  F+                  D  +   + + CR +  +  Y V  
Sbjct: 152 HWNLITTFILRNVMWFLLQLV--------------DHEVHESNEVWCRCITTIFNYFVVT 197

Query: 240 NYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW-- 297
           N++W+ VEG YL+T +  +  +E+    L++ IGW +P   +V W I K  YE+E CW  
Sbjct: 198 NFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFG 257

Query: 298 -TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTL 356
                 ++Y  I + PI+  + +NF+    ++ I+++KL+A+   +T    +  K+TL L
Sbjct: 258 KEPGDLVDY--IYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVL 315

Query: 357 IPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 416
           +PLLG   ++F     E     + FI   + L   SFQG  V++ YCF N EV+   RK 
Sbjct: 316 LPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQ--SFQGFFVSVFYCFFNGEVRSAVRKR 373

Query: 417 WERWRLEHLHIQRDSSMKPLKCPTS 441
           W RW+ +H H  R    + +  PTS
Sbjct: 374 WHRWQ-DH-HSLRVPMARAMSIPTS 396


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  184 bits (468), Expect = 1e-46
 Identities = 116/421 (27%), Positives = 211/421 (50%), Gaps = 25/421 (5%)

Query: 29  TVSLWETVQKWREYRRQCQRSLTEDP-PPATDLFCNRTFDEYACWPDGEPGSFVNVSCPW 87
           ++ L  T  K    + +C + + +DP   A  ++CNRT+D + CW D   G+     CP 
Sbjct: 31  SIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPD 90

Query: 88  YLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYII 147
           Y  +    P   V + C  +G W +   S+  W + ++C  +   E+      L +L II
Sbjct: 91  Y--FQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTH-EKVKTALNLFYLTII 147

Query: 148 YTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYST 207
              G+ LS ++L+I+  I   F+ L C R  +H NLF SF+  ++   I        + T
Sbjct: 148 ---GHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTII--------HLT 196

Query: 208 AAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFR 267
           A   +Q    L   + +SC++   +  Y +  NY+W+L EG+YL+TL+  +V +E+    
Sbjct: 197 AVANNQ---ALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLM 253

Query: 268 LYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRV 327
            Y  +GWG PL+      I + LY ++ CW  +S+ +   II  PI  A+ VN    + +
Sbjct: 254 WYYFLGWGFPLIPACIHAIARSLYYNDNCWI-SSDTHLLYIIHGPICAALLVNLFFLLNI 312

Query: 328 ICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMD-EHARGTLRFIKLFT 386
           + ++++KLK     ++++  +  ++TL L+PLLG   V+  +  + + A     +I    
Sbjct: 313 VRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHI- 371

Query: 387 ELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLH-IQRDSSMKPLKCPTSSLSS 445
                 FQGL+V+ ++CF N EVQ   R++W +++++  +      +++      S++S 
Sbjct: 372 ---LMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISD 428

Query: 446 G 446
           G
Sbjct: 429 G 429


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  181 bits (458), Expect = 2e-45
 Identities = 115/370 (31%), Positives = 183/370 (49%), Gaps = 31/370 (8%)

Query: 60  LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118
           L CN + D    CWP    G  V   CP +          + YR C A G W  + N   
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98

Query: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178
                SEC+E    E+ S     + + I Y +G+ +S  AL++A  + L  R + C RN 
Sbjct: 99  ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNI 153

Query: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVA 238
           IH NL ++FILR  + F+    +      + + HQ        +   CRLV     Y   
Sbjct: 154 IHWNLISAFILRNATWFVVQLTM------SPEVHQ-------SNVGWCRLVTAAYNYFHV 200

Query: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW- 297
            N++W+  EG YL+T +  +  +++    +++ IGWGVP   +V W I K  Y++E CW 
Sbjct: 201 TNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWF 260

Query: 298 TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLI 357
            +   +    I + P++  + +NF+    ++ I+++KL+A+   +T    +  K+TL L+
Sbjct: 261 GKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLL 320

Query: 358 PLLGTHEVIFAFV---MDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFR 414
           PLLG   ++F FV    DE +R    +   F E    SFQG  V++ YCF+N+EV+   R
Sbjct: 321 PLLGITYMLF-FVNPGEDEVSRVVFIYFNSFLE----SFQGFFVSVFYCFLNSEVRSAIR 375

Query: 415 KSWERWRLEH 424
           K W RW+ +H
Sbjct: 376 KRWHRWQDKH 385


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  168 bits (426), Expect = 8e-42
 Identities = 104/328 (31%), Positives = 169/328 (51%), Gaps = 30/328 (9%)

Query: 101 YRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALV 160
           YR C A G W  + N        SEC+E    E+ S     + + I Y +G+ +S  AL+
Sbjct: 44  YRECLANGSWAARVN-------YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALL 95

Query: 161 IASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSY 220
           +A  + L  R + C RN IH NL ++FILR  + F+    +      + + HQ       
Sbjct: 96  VAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------SPEVHQ------- 142

Query: 221 QDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLF 280
            +   CRLV     Y    N++W+  EG YL+T +  +  +++    +++ IGWGVP   
Sbjct: 143 SNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPI 202

Query: 281 VVPWGIVKYLYEDEGCW-TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANL 339
           +V W I K  Y++E CW  +   +    I + P++  + +NF+    ++ I+++KL+A+ 
Sbjct: 203 IVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAST 262

Query: 340 MCKTDIKCRLAKSTLTLIPLLGTHEVIFAFV---MDEHARGTLRFIKLFTELSFTSFQGL 396
             +T    +  K+TL L+PLLG   ++F FV    DE +R    +   F E    SFQG 
Sbjct: 263 TSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDEVSRVVFIYFNSFLE----SFQGF 317

Query: 397 MVAILYCFVNNEVQLEFRKSWERWRLEH 424
            V++ YCF+N+EV+   RK W RW+ +H
Sbjct: 318 FVSVFYCFLNSEVRSAIRKRWHRWQDKH 345


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  167 bits (423), Expect = 2e-41
 Identities = 107/301 (35%), Positives = 150/301 (49%), Gaps = 19/301 (6%)

Query: 36  VQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSV 95
           + + RE    C ++  E   P T L C  T+D   CWP    G +V + CP +    SS 
Sbjct: 31  ITQLREDESACLQAAEE--MPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSS- 87

Query: 96  PQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALS 155
             G V R CT  G W      S P+              +  E     + IIYTVG+++S
Sbjct: 88  ESGAVKRDCTITG-W------SEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSIS 140

Query: 156 FSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWD 215
             AL +A  IL+  R LHC RNY+H  LF +FIL+A +VF+KDAAL   +S       + 
Sbjct: 141 IVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAAL--FHSDDTDHCSFS 198

Query: 216 GLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWG 275
            +L       C++      +    N+ WLL E VYL  LLA +  S +  F   V  GWG
Sbjct: 199 TVL-------CKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWG 251

Query: 276 VPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKL 335
           +P+LF   W   K  +ED  CW  +    YW II+ PI+ ++GVNF +F+ +I I+V KL
Sbjct: 252 LPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL 311

Query: 336 K 336
           +
Sbjct: 312 E 312


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  165 bits (418), Expect = 7e-41
 Identities = 115/399 (28%), Positives = 183/399 (45%), Gaps = 60/399 (15%)

Query: 60  LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118
           L CN + D    CWP    G  V   CP +          + YR C A G W  + N   
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98

Query: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFR-------- 170
                SEC+E    E+ S     + + I Y +G+ +S  AL++A  + L  R        
Sbjct: 99  ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGD 153

Query: 171 ---------------------HLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAA 209
                                 + C RN IH NL ++FILR  + F+    +      + 
Sbjct: 154 QADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------SP 207

Query: 210 QQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLY 269
           + HQ        +   CRLV     Y    N++W+  EG YL+T +  +  +++    ++
Sbjct: 208 EVHQ-------SNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMF 260

Query: 270 VSIGWGVPLLFVVPWGIVKYLYEDEGCW-TRNSNMNYWLIIRLPILFAIGVNFLIFVRVI 328
           + IGWGVP   +V W I K  Y++E CW  +   +    I + P++  + +NF+    ++
Sbjct: 261 ICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIV 320

Query: 329 CIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFV---MDEHARGTLRFIKLF 385
            I+++KL+A+   +T    +  K+TL L+PLLG   ++F FV    DE +R    +   F
Sbjct: 321 RILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDEVSRVVFIYFNSF 379

Query: 386 TELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEH 424
            E    SFQG  V++ YCF+N+EV+   RK W RW+ +H
Sbjct: 380 LE----SFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKH 414


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  152 bits (384), Expect = 6e-37
 Identities = 108/370 (29%), Positives = 172/370 (46%), Gaps = 45/370 (12%)

Query: 60  LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118
           L CN + D    CWP    G  V   CP +          + YR C A G W  + N   
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98

Query: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178
                SEC+E    E+ S     + + I Y +G+ +S  AL++A  + L  R + C RN 
Sbjct: 99  ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNI 153

Query: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVA 238
           IH NL ++FILR  + F+    +      + + HQ        +   CRLV     Y   
Sbjct: 154 IHWNLISAFILRNATWFVVQLTM------SPEVHQ-------SNVGWCRLVTAAYNYFHV 200

Query: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW- 297
            N++W+  EG YL+T +  +  +++    +++ IGWGVP   +V W I K  Y++E CW 
Sbjct: 201 TNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWF 260

Query: 298 TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLI 357
            +   +    I + P++  + +NF+    ++ I+++KL+A+   +T    +  K+TL L+
Sbjct: 261 GKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLL 320

Query: 358 PLLGTHEVIFAFV---MDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFR 414
           PLLG   ++F FV    DE +R    +   F E    SFQ              V+   R
Sbjct: 321 PLLGITYMLF-FVNPGEDEVSRVVFIYFNSFLE----SFQ--------------VRSAIR 361

Query: 415 KSWERWRLEH 424
           K W RW+ +H
Sbjct: 362 KRWHRWQDKH 371


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 83/311 (26%), Positives = 134/311 (43%), Gaps = 42/311 (13%)

Query: 150 VGYALSFSALV---IASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYS 206
           VG +LS   LV   +  A+L     +   R +IH NL  SF +    V +          
Sbjct: 572 VGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANL--SFAVLVAQVLL---------- 619

Query: 207 TAAQQHQWDGLLSYQ---DSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQ 263
                     L+S++    +  C+++ +L+ Y   + + W+LVEG++LY+++     SE 
Sbjct: 620 ----------LISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSED 669

Query: 264 WIFRLYVSIGWGVPLLF-VVPWGIVKYLY-EDEGCWTRNSNMNYWLIIRLPILFAIGVNF 321
              R Y  +GWG PLL  ++        Y     CW   ++   W  +  P LF I VN 
Sbjct: 670 SKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFV-APALFVIVVNI 728

Query: 322 LIFVRVICIVVSKLKANLMCKTDIKC--RLAKSTLTLIPLLGTHEVIFAFVMDEHARGTL 379
            I + V  ++      N     D       AK+   L+P+LGT  V     ++  A   +
Sbjct: 729 GILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCA---V 785

Query: 380 RFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCP 439
            F  +F  L+  S QGL + + +C +N+EV+  F+   + W L      R S+ KP    
Sbjct: 786 VFQYMFATLN--SLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTS-SSARTSNAKPFH-- 840

Query: 440 TSSLSSGATAG 450
            S L +G   G
Sbjct: 841 -SDLMNGTRPG 850


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 79/279 (28%), Positives = 124/279 (44%), Gaps = 33/279 (11%)

Query: 144 LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKW 203
           L +I  VG ALS   L++     L  R +  +R  IHL+L     + + ++F+       
Sbjct: 498 LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGS-TIFL------- 549

Query: 204 MYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQ 263
               A  +++       Q  L CRLV  L+ YC  A + W+ +EG+ LY L+      + 
Sbjct: 550 ----AGIENEGG-----QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 600

Query: 264 WIFRLYVSIGWGVPLLFVVPWGIVKYLY-----EDEGCWTRNSNMNYWLIIRLPILFAIG 318
              R    IG+GVPLL V   G+   +Y         CW        W  +  P+ F I 
Sbjct: 601 LSTRWLCLIGYGVPLLIV---GVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIIL 656

Query: 319 VNFLIFVRVICIVVSKL-KANLMCKTDIKCR-LAKSTLTLIPLLGTHEVIFAFVMDEHAR 376
            N +IFV  +  +  K  + N   K   K R L  + +  + LLG   V   F+ D+   
Sbjct: 657 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDR-- 714

Query: 377 GTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRK 415
            +L    +FT L+    QG  + +L+C +N +V+ E+RK
Sbjct: 715 -SLVLTYVFTILN--CLQGAFLYLLHCLLNKKVREEYRK 750


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 79/279 (28%), Positives = 124/279 (44%), Gaps = 33/279 (11%)

Query: 144 LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKW 203
           L +I  VG ALS   L++     L  R +  +R  IHL+L     + + ++F+       
Sbjct: 454 LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGS-TIFL------- 505

Query: 204 MYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQ 263
               A  +++       Q  L CRLV  L+ YC  A + W+ +EG+ LY L+      + 
Sbjct: 506 ----AGIENEGG-----QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 556

Query: 264 WIFRLYVSIGWGVPLLFVVPWGIVKYLY-----EDEGCWTRNSNMNYWLIIRLPILFAIG 318
              R    IG+GVPLL V   G+   +Y         CW        W  +  P+ F I 
Sbjct: 557 LSTRWLCLIGYGVPLLIV---GVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIIL 612

Query: 319 VNFLIFVRVICIVVSKL-KANLMCKTDIKCR-LAKSTLTLIPLLGTHEVIFAFVMDEHAR 376
            N +IFV  +  +  K  + N   K   K R L  + +  + LLG   V   F+ D+   
Sbjct: 613 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDR-- 670

Query: 377 GTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRK 415
            +L    +FT L+    QG  + +L+C +N +V+ E+RK
Sbjct: 671 -SLVLTYVFTILN--CLQGAFLYLLHCLLNKKVREEYRK 706


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 79/279 (28%), Positives = 124/279 (44%), Gaps = 33/279 (11%)

Query: 144 LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKW 203
           L +I  VG ALS   L++     L  R +  +R  IHL+L     + + ++F+       
Sbjct: 547 LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGS-TIFL------- 598

Query: 204 MYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQ 263
               A  +++       Q  L CRLV  L+ YC  A + W+ +EG+ LY L+      + 
Sbjct: 599 ----AGIENEGG-----QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 649

Query: 264 WIFRLYVSIGWGVPLLFVVPWGIVKYLY-----EDEGCWTRNSNMNYWLIIRLPILFAIG 318
              R    IG+GVPLL V   G+   +Y         CW        W  +  P+ F I 
Sbjct: 650 LSTRWLCLIGYGVPLLIV---GVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIIL 705

Query: 319 VNFLIFVRVICIVVSKL-KANLMCKTDIKCR-LAKSTLTLIPLLGTHEVIFAFVMDEHAR 376
            N +IFV  +  +  K  + N   K   K R L  + +  + LLG   V   F+ D+   
Sbjct: 706 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDR-- 763

Query: 377 GTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRK 415
            +L    +FT L+    QG  + +L+C +N +V+ E+RK
Sbjct: 764 -SLVLTYVFTILN--CLQGAFLYLLHCLLNKKVREEYRK 799


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 73/276 (26%), Positives = 114/276 (41%), Gaps = 25/276 (9%)

Query: 142  LFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAAL 201
            L L +I  VG  +S   L I  +     R L   RN IH NL  +  L  L   +     
Sbjct: 858  LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLV----- 912

Query: 202  KWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLS 261
                          G+   Q  ++C +   L+ Y   A + WL +EGV+LY LL     S
Sbjct: 913  --------------GIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFES 958

Query: 262  EQWIFRLYVSIGWGVPLLFVVPWGIVKY--LYEDEGCWTRNSNMNYWLIIRLPILFAIGV 319
            E    + Y   G+  P L V     + Y     ++ CW R  N   W  I  P+ F I V
Sbjct: 959  EYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG-PVSFVIVV 1017

Query: 320  NFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTL 379
            N L+F+ V    + +  + L   +     +    L  I LL    + +AF +    + ++
Sbjct: 1018 N-LVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESV 1076

Query: 380  RFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRK 415
                LFT  +F +FQG+ + + +C +  +V  E+ K
Sbjct: 1077 VMAYLFT--TFNAFQGVFIFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 73/276 (26%), Positives = 114/276 (41%), Gaps = 25/276 (9%)

Query: 142  LFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAAL 201
            L L +I  VG  +S   L I  +     R L   RN IH NL  +  L  L   +     
Sbjct: 853  LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLV----- 907

Query: 202  KWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLS 261
                          G+   Q  ++C +   L+ Y   A + WL +EGV+LY LL     S
Sbjct: 908  --------------GIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFES 953

Query: 262  EQWIFRLYVSIGWGVPLLFVVPWGIVKY--LYEDEGCWTRNSNMNYWLIIRLPILFAIGV 319
            E    + Y   G+  P L V     + Y     ++ CW R  N   W  I  P+ F I V
Sbjct: 954  EYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG-PVSFVIVV 1012

Query: 320  NFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTL 379
            N L+F+ V    + +  + L   +     +    L  I LL    + +AF +    + ++
Sbjct: 1013 N-LVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESV 1071

Query: 380  RFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRK 415
                LFT  +F +FQG+ + + +C +  +V  E+ K
Sbjct: 1072 VMAYLFT--TFNAFQGVFIFVFHCALQKKVHKEYSK 1105


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 81/325 (24%), Positives = 132/325 (40%), Gaps = 41/325 (12%)

Query: 142  LFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAAL 201
            L L +I  VG  +S   L I       FR L   RN IH NL  +  +      I     
Sbjct: 832  LLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLI----- 886

Query: 202  KWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLS 261
                          G+   + +++C +   L+ +   A + W+ +EGV LY +L     S
Sbjct: 887  --------------GIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFES 932

Query: 262  EQWIFRLYVSIGWGVPLLFVVPWGIVKY--LYEDEGCWTRNSNMNYWLIIRLPILFAIGV 319
            E    + Y   G+  P   V     + Y     ++ CW    N   W  I  P+ F I +
Sbjct: 933  EYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIG-PVTFIILL 991

Query: 320  NFLIFVRVICIVV---SKLKANLMCKTDIKCRLAKSTLTLIPLLG-THEVIFAFVMDEHA 375
            N +  V  +C +V   + LK +     +IK  +      L+ LLG T      F+ +E  
Sbjct: 992  NIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVL-GAFALLCLLGLTWSFGLLFINEE-- 1048

Query: 376  RGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKP 435
              T+    LFT   F +FQG+ + I +C +  +V+ E+ K +      H +        P
Sbjct: 1049 --TIVMAYLFT--IFNAFQGVFIFIFHCALQKKVRKEYGKCF-----RHSYC---CGGLP 1096

Query: 436  LKCPTSSLSSGATAGSSMYTATCQA 460
             + P SS+ +  T  S+ Y++  Q+
Sbjct: 1097 TESPHSSVKASTTRTSARYSSGTQS 1121


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 81/319 (25%), Positives = 123/319 (38%), Gaps = 42/319 (13%)

Query: 142  LFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAAL 201
            L L +I  VG  LS   L+I       FR L   RN IH NL  S  +  L   I     
Sbjct: 875  LLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLI----- 929

Query: 202  KWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLS 261
                          G+      ++C +   L+ +   A + W+ +EGV LY +L     S
Sbjct: 930  --------------GINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFES 975

Query: 262  EQWIFRLYVSIGWGVPLLFVVPWGIVKY--LYEDEGCWTRNSNMNYW-------LIIRLP 312
            E    + +  +G+G+P L V     V Y     D+ CW R      W       LII L 
Sbjct: 976  EHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLN 1035

Query: 313  ILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMD 372
            ++F     + +F     +       + +   D +  +    +  I LL    + +AF + 
Sbjct: 1036 VIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLM 1095

Query: 373  EHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSS 432
                 T+    LFT   F S QG+ + I +C +  +V+ E+ K         L     S 
Sbjct: 1096 YINESTVIMAYLFT--IFNSLQGMFIFIFHCVLQKKVRKEYGKC--------LRTHCCSG 1145

Query: 433  MKPLKCPTSSLSSGATAGS 451
                K   SS+ SG T+GS
Sbjct: 1146 ----KSTESSIGSGKTSGS 1160


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 79/332 (23%), Positives = 131/332 (39%), Gaps = 48/332 (14%)

Query: 104 CTAEGLWLQKD----NSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSAL 159
           C+   L+L       N S  +  L +  E +RG    PEE+ L   + + VG  +SF AL
Sbjct: 619 CSVAALYLDSTACFCNHSTSFAILLQIYEVQRG----PEEESLLRTLSF-VGCGVSFCAL 673

Query: 160 VIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLS 219
                + L        R  +H NL  +F L +   F+  +             +W    +
Sbjct: 674 TTTFLLFLVAGVPKSERTTVHKNL--TFSLASAEGFLMTS-------------EW----A 714

Query: 220 YQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPL- 278
             + ++C  V + M +     + W+LVEG+ L+  +    +      RLY + GWGVP+ 
Sbjct: 715 KANEVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGMRLYHATGWGVPVG 774

Query: 279 LFVVPWGIVKYLYEDEG-CWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKA 337
           +  V   ++ + Y   G CW        W  +  P+LF +  N  I  RV+ I VS  + 
Sbjct: 775 IVAVTLAMLPHDYVAPGHCWLNVHTNAIWAFVG-PVLFVLTANTCILARVVMITVSSARR 833

Query: 338 NLMCKTDIKC----------RLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTE 387
                +   C             K  L L+P+LG   +    V    A         +  
Sbjct: 834 RARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLTWLAGILVHLSPAWA-------YAA 886

Query: 388 LSFTSFQGLMVAILYCFVNNEVQLEFRKSWER 419
           +   S QGL + ++Y   N EV+   ++  E+
Sbjct: 887 VGLNSIQGLYIFLVYAACNEEVRSALQRMAEK 918


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 68/272 (25%), Positives = 115/272 (42%), Gaps = 31/272 (11%)

Query: 147 IYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYS 206
           I  +G  +S   L I       F  +  TR  IH NL  S  L  L   +          
Sbjct: 430 ITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLV---------- 479

Query: 207 TAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIF 266
                    G+ +  + L C ++  L+ Y   A + W+ +EG++LY ++   + ++ ++ 
Sbjct: 480 ---------GINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLH 530

Query: 267 RLYVSIGWGVPLLFVVPWGIVKYLY--EDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIF 324
           + +   G+  P + V     + Y Y    + CW    N   W  I  P    I VN L F
Sbjct: 531 KNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIG-PACLIILVNLLAF 589

Query: 325 VRVICIV---VSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRF 381
             +I  V    + LK  + C  +I+   A+  L L+ LLGT   IF  +   HA     +
Sbjct: 590 GVIIYKVFRHTAGLKPEVSCFENIR-SCARGALALLFLLGT-TWIFGVLHVVHASVVTAY 647

Query: 382 IKLFTELSFTSFQGLMVAILYCFVNNEVQLEF 413
             LFT  +  +FQG+ + +  C ++ ++Q E+
Sbjct: 648 --LFTVSN--AFQGMFIFLFLCVLSRKIQEEY 675


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 81/321 (25%), Positives = 129/321 (40%), Gaps = 52/321 (16%)

Query: 108  GLWLQKDNSSLPWRDLSE--CEESKRGE-----RSSPEEQL---LFLYIIYT-VGYALSF 156
            G+W  +D   L  R+ S   C  S+ G       +SP E+L   L L  ++T V  A+S 
Sbjct: 2493 GVWTARD-CELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSV 2551

Query: 157  SALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDG 216
            +ALV+ +AILL  R L      IH N+ A+  +  L   +                   G
Sbjct: 2552 AALVLTAAILLSLRSLKSNVRGIHANVAAALGVAELLFLL-------------------G 2592

Query: 217  LLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGV 276
            +    + L C  V +L+ Y   + + WL V+G++LY +       ++   R Y ++GWGV
Sbjct: 2593 IHRTHNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHALGWGV 2652

Query: 277  P-LLFVVPWGIVKYLY-EDEGCWTRNSNMNYWLIIRLPILFAI--GVNFLIFVRVICIV- 331
            P +L  +  G+    Y   + CW        W      +L  +  G  FL+  R  C   
Sbjct: 2653 PAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMFLLAARTSCSTG 2712

Query: 332  --VSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELS 389
               +K  + L  ++     L  S   L  LL  +  I AF               +    
Sbjct: 2713 QREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAF--------------HYLHAG 2758

Query: 390  FTSFQGLMVAILYCFVNNEVQ 410
                QGL V +L+C +N + +
Sbjct: 2759 LCGLQGLAVLLLFCVLNADAR 2779


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,193,684
Number of Sequences: 37866
Number of extensions: 832117
Number of successful extensions: 2867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 2673
Number of HSP's gapped (non-prelim): 96
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.