Guide to the Human Genome
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Search of human proteins with 157419142

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157419142 tumor necrosis factor (ligand) superfamily, member
18 [Homo sapiens]
         (199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157419142 tumor necrosis factor (ligand) superfamily, member ...   415   e-116
gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]           32   0.47 
gi|14589896 megalencephalic leukoencephalopathy with subcortical...    30   1.8  
gi|21237732 megalencephalic leukoencephalopathy with subcortical...    30   1.8  
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]                28   3.9  
gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens]              28   6.7  
gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens]               27   8.8  
gi|188528663 solute carrier organic anion transporter family, me...    27   8.8  

>gi|157419142 tumor necrosis factor (ligand) superfamily, member 18
           [Homo sapiens]
          Length = 199

 Score =  415 bits (1067), Expect = e-116
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MTLHPSPITCEFLFSTALISPKMCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFL 60
           MTLHPSPITCEFLFSTALISPKMCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFL
Sbjct: 1   MTLHPSPITCEFLFSTALISPKMCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFL 60

Query: 61  CSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIY 120
           CSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIY
Sbjct: 61  CSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIY 120

Query: 121 GQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQV 180
           GQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQV
Sbjct: 121 GQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQV 180

Query: 181 LKNNTYWGIILLANPQFIS 199
           LKNNTYWGIILLANPQFIS
Sbjct: 181 LKNNTYWGIILLANPQFIS 199


>gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]
          Length = 1888

 Score = 31.6 bits (70), Expect = 0.47
 Identities = 15/74 (20%), Positives = 38/74 (51%), Gaps = 13/74 (17%)

Query: 130 NDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDT-------------IDLIFNS 176
           N +    V+L+ N+++ + +T + ++ ++  T  L++ ++             + ++ N 
Sbjct: 441 NRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNC 500

Query: 177 EHQVLKNNTYWGII 190
              +LKNNTYW ++
Sbjct: 501 GEALLKNNTYWPLV 514


>gi|14589896 megalencephalic leukoencephalopathy with subcortical
           cysts 1 gene product [Homo sapiens]
          Length = 377

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 121 GQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTI 170
           G ++ +AN  D  PF  R+ K+  +++ +   S +  +GG   L+V D++
Sbjct: 176 GSMSDSANILDEVPFPARVLKSYSVVEVIAGISAV--LGGIIALNVDDSV 223


>gi|21237732 megalencephalic leukoencephalopathy with subcortical
           cysts 1 gene product [Homo sapiens]
          Length = 377

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 121 GQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTI 170
           G ++ +AN  D  PF  R+ K+  +++ +   S +  +GG   L+V D++
Sbjct: 176 GSMSDSANILDEVPFPARVLKSYSVVEVIAGISAV--LGGIIALNVDDSV 223


>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
          Length = 1454

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 12/46 (26%), Positives = 24/46 (52%)

Query: 82  AKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNA 127
           + F P+  K+ M   + P  N+++ W   + + G+  +  Q+AP A
Sbjct: 146 SNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSFQLAPEA 191


>gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens]
          Length = 389

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 14/30 (46%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query: 108 KLEILQNGLYLIYGQVAPNANYNDVAPFEV 137
           +LE+L +G Y IY QV    N+ D A +EV
Sbjct: 292 ELEVLVDGTYFIYSQVY-YINFTDFASYEV 320


>gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens]
          Length = 391

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 1/31 (3%)

Query: 108 KLEILQNGLYLIYGQV-APNANYNDVAPFEV 137
           +LE+L +G Y IY QV     N+ D A +EV
Sbjct: 292 ELEVLVDGTYFIYSQVEVYYINFTDFASYEV 322


>gi|188528663 solute carrier organic anion transporter family,
           member 2A1 [Homo sapiens]
          Length = 643

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 12/42 (28%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 19  ISPKMCLSHLENMPLS--HSRTQGAQRSSWKLWLFCSIVMLL 58
           +  ++C  H +++P S  HS TQ  Q+ +  +W    +  LL
Sbjct: 138 LQAELCQKHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLL 179


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,056,696
Number of Sequences: 37866
Number of extensions: 331368
Number of successful extensions: 776
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 774
Number of HSP's gapped (non-prelim): 8
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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