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Search of human proteins with 157364974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157364974 sucrase-isomaltase [Homo sapiens]
(1827 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157364974 sucrase-isomaltase [Homo sapiens] 3824 0.0
gi|221316699 maltase-glucoamylase [Homo sapiens] 2333 0.0
gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapi... 1645 0.0
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens] 714 0.0
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens] 714 0.0
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens] 714 0.0
gi|66346737 glucosidase, alpha; neutral C [Homo sapiens] 298 3e-80
gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens] 277 6e-74
gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens] 277 6e-74
gi|153791946 hypothetical protein LOC57462 [Homo sapiens] 64 1e-09
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 34 1.1
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 34 1.1
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 34 1.1
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 34 1.1
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens] 33 3.3
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] 33 3.3
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 32 4.3
gi|221307475 N-acylsphingosine amidohydrolase 2 isoform b [Homo ... 32 4.3
gi|221218981 N-acylsphingosine amidohydrolase 2 isoform a [Homo ... 32 4.3
>gi|157364974 sucrase-isomaltase [Homo sapiens]
Length = 1827
Score = 3824 bits (9916), Expect = 0.0
Identities = 1827/1827 (100%), Positives = 1827/1827 (100%)
Query: 1 MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDS 60
MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDS
Sbjct: 1 MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDS 60
Query: 61 GKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMT 120
GKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMT
Sbjct: 61 GKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMT 120
Query: 121 TTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEF 180
TTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEF
Sbjct: 121 TTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEF 180
Query: 181 TGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYG 240
TGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYG
Sbjct: 181 TGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYG 240
Query: 241 IGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSN 300
IGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSN
Sbjct: 241 IGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSN 300
Query: 301 AMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRW 360
AMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRW
Sbjct: 301 AMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRW 360
Query: 361 NYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQ 420
NYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQ
Sbjct: 361 NYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQ 420
Query: 421 KYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNP 480
KYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNP
Sbjct: 421 KYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNP 480
Query: 481 NCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMY 540
NCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMY
Sbjct: 481 NCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMY 540
Query: 541 SKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAH 600
SKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAH
Sbjct: 541 SKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAH 600
Query: 601 WLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSR 660
WLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSR
Sbjct: 601 WLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSR 660
Query: 661 NHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHE 720
NHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHE
Sbjct: 661 NHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHE 720
Query: 721 FYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDM 780
FYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDM
Sbjct: 721 FYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDM 780
Query: 781 YLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDT 840
YLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDT
Sbjct: 781 YLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDT 840
Query: 841 IQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN 900
IQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN
Sbjct: 841 IQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN 900
Query: 901 AHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGC 960
AHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGC
Sbjct: 901 AHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGC 960
Query: 961 VWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRV 1020
VWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRV
Sbjct: 961 VWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRV 1020
Query: 1021 EVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRS 1080
EVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRS
Sbjct: 1021 EVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRS 1080
Query: 1081 SGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPP 1140
SGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPP
Sbjct: 1081 SGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPP 1140
Query: 1141 GYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGP 1200
GYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGP
Sbjct: 1141 GYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGP 1200
Query: 1201 TPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDI 1260
TPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDI
Sbjct: 1201 TPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDI 1260
Query: 1261 DYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVF 1320
DYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVF
Sbjct: 1261 DYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVF 1320
Query: 1321 VKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVD 1380
VKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVD
Sbjct: 1321 VKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVD 1380
Query: 1381 FYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEA 1440
FYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEA
Sbjct: 1381 FYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEA 1440
Query: 1441 EQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGD 1500
EQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGD
Sbjct: 1441 EQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGD 1500
Query: 1501 NYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNI 1560
NYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNI
Sbjct: 1501 NYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNI 1560
Query: 1561 ANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKP 1620
ANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKP
Sbjct: 1561 ANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKP 1620
Query: 1621 TWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDT 1680
TWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDT
Sbjct: 1621 TWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDT 1680
Query: 1681 INLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLY 1740
INLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLY
Sbjct: 1681 INLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLY 1740
Query: 1741 LSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNE 1800
LSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNE
Sbjct: 1741 LSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNE 1800
Query: 1801 DTTNMILRIDLTTHNVTLEEPIEINWS 1827
DTTNMILRIDLTTHNVTLEEPIEINWS
Sbjct: 1801 DTTNMILRIDLTTHNVTLEEPIEINWS 1827
>gi|221316699 maltase-glucoamylase [Homo sapiens]
Length = 1857
Score = 2333 bits (6047), Expect = 0.0
Identities = 1085/1855 (58%), Positives = 1383/1855 (74%), Gaps = 40/1855 (2%)
Query: 4 KKFSGLEISLIVLFVIVTIIAIALIVVLAT---KTPAVDEISDSTSTPATTRV------- 53
KKF+ LEI L VL +++ II+I LIV+LA K+ A D + T P TT
Sbjct: 7 KKFTTLEIVLSVLLLVLFIISIVLIVLLAKESLKSTAPDPGTTGTPDPGTTGTPDPGTTG 66
Query: 54 -----TTNPSDSG---------KCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWN 99
TT P D G +CP V+N+ RINCIP+Q PT+ C QRGCCW P
Sbjct: 67 TTHARTTGPPDPGTTGTTPVSAECP-VVNELE--RINCIPDQPPTKATCDQRGCCWNPQG 123
Query: 100 DSLIPWCFFVDNHGYNVQ-DMTTTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRF 158
+PWC++ NH Y+V+ ++ T+ G A+L +PS +FG+++++VL T + QT NRF
Sbjct: 124 AVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGSNVDNVLLTAEYQTSNRF 183
Query: 159 RFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIG 218
FK+TD N R+EVPH++V+ F+G + Y V++++ PFSI+V R+SN + LFD+SIG
Sbjct: 184 HFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIG 243
Query: 219 PLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQ 278
PL+++DQ+LQ+STRLPS +YG+GE VH+++RHD++WKTWPIF RD P N NLYG Q
Sbjct: 244 PLLFADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQ 303
Query: 279 TFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQY 338
TFF+C+ED SG SFGVFLMNSNAME+ +QP P +TYR GGILDFY+ LG+TPEQVVQ+Y
Sbjct: 304 TFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEY 363
Query: 339 QQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDF 398
+L+G PA+P+YW LGF LSR+ Y +LD ++EVV RNR A +P+D Q DIDYM++++DF
Sbjct: 364 LELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDF 423
Query: 399 TYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHVWINESD 458
TYD V F G P+FV +LH++GQK VII+DPAIS ++ Y Y+RG+ +W+N SD
Sbjct: 424 TYDSVDFKGFPEFVNELHNNGQKLVIIVDPAIS-NNSSSSKPYGPYDRGSDMKIWVNSSD 482
Query: 459 GSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTK 518
G TP+IGEVWPG TV+PD+TNPNC WW E +FH +V++DG+WIDMNEVS+F+ GS
Sbjct: 483 GVTPLIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVS 542
Query: 519 GCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVF 578
GC+ N LN PPFTP ILD ++ KT+CMDAVQ+WGKQYD+H+LYGYSMA+AT +A + VF
Sbjct: 543 GCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVF 602
Query: 579 PNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFV 638
PNKRSFILTRSTFAGSG+ AAHWLGDNTA+W+ + WSI G+LEF+LFGIP+VG DICGF
Sbjct: 603 PNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFA 662
Query: 639 AETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPF 698
+T EELCRRWMQLGAFYPFSRNHN GY+ QDPA FG +SLL+ SSR YL IRYTLLP+
Sbjct: 663 LDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPY 722
Query: 699 LYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIP 758
LYTLF++AH G+TVARP+LHEFYED ++W +FLWGP LLITPVL +GA+ V AY+P
Sbjct: 723 LYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVP 782
Query: 759 DAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIV 818
DA+WYDYE+G++ WRKQ+V+M LP DKIGLHLRGGYI P Q+P+ TT ASRKNPLGLI+
Sbjct: 783 DAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLII 842
Query: 819 ALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTV 878
AL EN AKG+ FWD+GETKDT+ N Y+L FSV+ N L++ + S+Y++ LAF +
Sbjct: 843 ALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEI 902
Query: 879 KILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSEN 938
KILG T+ + V V N P TYD++ +V +I D+ L LG ++V+W+ +
Sbjct: 903 KILG-TEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIRDE 961
Query: 939 ERFNCYPDADLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITAD 998
E+ +CYPD + A+ + CT RGC+W +S S P CYF ++ YSV+ +Y+S G TAD
Sbjct: 962 EKIDCYPDENGASAENCTARGCIWEASNS-SGVPFCYF--VNDLYSVSDVQYNSHGATAD 1018
Query: 999 LQLNTANARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTY 1058
+ L ++ PS P++ LR++V YHKN+MLQFKIYDP K RYEVPVPLNIP+ P ST
Sbjct: 1019 ISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTP 1078
Query: 1059 EDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVE 1118
E +LYDV IK+NPFGI+IRR+S+G +IWDS L GF F+D FI+ISTRLPS+Y+YGFGE E
Sbjct: 1079 EGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETE 1138
Query: 1119 HTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQ 1178
H +++RDL W+TWGMF+RDQPPGYK NSYG HPYYM LEE+G+AHGV LLNSNAMDVTFQ
Sbjct: 1139 HRSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQ 1198
Query: 1179 PTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSE 1238
P PALTYRT GG+LDFY+FLGPTPE+ T+QY E+IG PVM YW+LGFQLCRYGY N SE
Sbjct: 1199 PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 1258
Query: 1239 VRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDP 1298
+ LYD MVAA IPYDVQY+DIDYMERQLDFT+ F P +++++ +GMR I+ILDP
Sbjct: 1259 IASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDP 1318
Query: 1299 AISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRA 1358
AISGNET+ YPAF RG ++DVF+K+PN DI W KVWPD P++ ++ +L D V RA
Sbjct: 1319 AISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRA 1378
Query: 1359 HVAFPDFFRTSTAEWWAREIVDFYN------EKMKFDGLWIDMNEPSSFVNGTTTNQCRN 1412
+VAFPDFFR STA+WW REI + YN +KFDG+WIDMNEPSSFVNG + CR+
Sbjct: 1379 YVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRD 1438
Query: 1413 DELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQ 1472
LN+PPY P L R GL +T+CME++QIL DG+ V HY+VHNLYGWSQ +PT++A+Q
Sbjct: 1439 ASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQ 1498
Query: 1473 KTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADICG 1532
+ TG+RG+VI+RST+P+SGRW GHWLGDN A WD + KSIIGMMEFSLFG+SYTGADICG
Sbjct: 1499 EVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICG 1558
Query: 1533 FFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPY 1592
FF ++EY +C RWMQLGAFYP+SRNHN TRRQDP SW+ F +SR +L RYTLLPY
Sbjct: 1559 FFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPY 1618
Query: 1593 FYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVP 1652
YT MH+ H G TV+RPLLHEF ++ TWDI QFL GPAF+V+PVLE + V AY P
Sbjct: 1619 LYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFP 1678
Query: 1653 NARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIV 1712
ARW+DY+TG DI RG+++T A D INLHVRGG+ILP QEPA NT SRQK M +
Sbjct: 1679 RARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKI 1738
Query: 1713 AADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYI-NKSETRLGS 1771
A DD A G LFWDDG+SIDTY + LY F+ +Q T+ S I+ YI + +LG
Sbjct: 1739 ALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGY 1798
Query: 1772 LHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEINW 1826
+ +WG G+ PV +V+++ +G + FN D T +L ID+T N++L + W
Sbjct: 1799 IEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTW 1853
>gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapiens]
Length = 1492
Score = 1645 bits (4260), Expect = 0.0
Identities = 802/1503 (53%), Positives = 1032/1503 (68%), Gaps = 38/1503 (2%)
Query: 347 MPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFN 406
M YW+LGFQL R+ Y++ + + A IP+D Q +DIDYME + DFT F
Sbjct: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFA 59
Query: 407 GLPQFVQDLHDHGQKYVIILDPAISIGRRANGTT-YATYERGNTQHVWINESDGSTPIIG 465
G P + + G + ++ILDPAIS N T Y + RG V+I + + G
Sbjct: 60 GFPALINRMKADGMRVILILDPAIS----GNETQPYPAFTRGVEDDVFIKYPNDGDIVWG 115
Query: 466 EVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQ-------YDGLWIDMNEVSSFIQGSTK 518
+++ +PDF + WW E + Q +DG+WIDMNE SSF+ G+
Sbjct: 116 KLYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVS 175
Query: 519 -GCNVNKLNYPPFTPDI--LDKLMYSKTICMDAVQ-----NWGKQYDVHSLYGYSMAIAT 570
GC LN+PP+ P + D+ + SKT+CM++ Q + + Y+VH+LYG+S T
Sbjct: 176 PGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPT 235
Query: 571 EQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLV 630
+AVQ+V +R ++TRSTF SGR A HWLGDNTA+W+Q++ SI G F LF
Sbjct: 236 YEAVQEV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQ---T 291
Query: 631 GADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLT 690
GADICGF + E+C RWMQLGAFYPFSRNHN+ G QDP + ++ V SR L
Sbjct: 292 GADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DAAFVNISRNVLQ 349
Query: 691 IRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGA 750
RYTLLP+LYTL KAH G TV RP+LHEF D +W D++FL GPA L++PVL++ A
Sbjct: 350 TRYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNA 409
Query: 751 DTVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASR 810
V+AY P A WYDY +G R + + P D I LH+RGGYI+P QEP + T SR
Sbjct: 410 RNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSR 469
Query: 811 KNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEG 870
KNPLGLI+AL EN AKG+ FWDDG+TKDT+ Y+L FSV+ N L++ + S+Y++
Sbjct: 470 KNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDP 529
Query: 871 TTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQ 930
LAF +KILG+ + + V V N P TYD++ +V +I D+ L LG ++V+
Sbjct: 530 NNLAFNEIKILGMEEP-SNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVE 588
Query: 931 WNQIFSENERFNCYPDADLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARY 990
W+ + E+ +CYPD + + + CT RGC+W +S S P CYF ++ YSV+ +Y
Sbjct: 589 WSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNS-SGVPFCYFV--NDLYSVSDVQY 645
Query: 991 SSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNI 1050
+S G TAD+ L ++ PS P++ LR++V YHKN+MLQFKIYDP RYEVPVPLNI
Sbjct: 646 NSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNI 705
Query: 1051 PTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEY 1110
P+ P ST E +LYDV IK+NPFGI+IRR+S+G +IWDS L GF FND FI+ISTRLPS+Y
Sbjct: 706 PSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKY 765
Query: 1111 IYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNS 1170
+YGFGE EHT+++RDL W+TWGMF+RDQPPGYK NSYG HPYYM LEE+G+AHGV LLNS
Sbjct: 766 LYGFGETEHTSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNS 825
Query: 1171 NAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCR 1230
NAMDVTFQP PALTYRT GG+LDFY+FLGPTPE+ T+QY E+IG PVM YW+LGFQLCR
Sbjct: 826 NAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCR 885
Query: 1231 YGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGM 1290
YGY N SE+ LYD MVAA IPYDVQY+DIDYMERQLDFT+ F P +++++ +GM
Sbjct: 886 YGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGM 945
Query: 1291 RYIIILDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTED 1350
R I+ILDPAISGNET+ YPAF RG ++DVF+K+PN DI W KVWPD P++ ++ +L D
Sbjct: 946 RVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWD 1005
Query: 1351 EAVNASRAHVAFPDFFRTSTAEWWAREIVDFYN------EKMKFDGLWIDMNEPSSFVNG 1404
V RA+VAFPDFFR STA+WW REI + YN +KFDG+WIDMNEPSSFVNG
Sbjct: 1006 SQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNG 1065
Query: 1405 TTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQM 1464
+ CR+ LN+PPY P L R GL +T+CME++QIL DG+ V HY+VHNLYGWSQ
Sbjct: 1066 AVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQT 1125
Query: 1465 KPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMS 1524
+PT++A+Q+ TG+RG+VI+RST+P+SGRW GHWLGDN A WD + KSIIGMMEFSLFG+S
Sbjct: 1126 RPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGIS 1185
Query: 1525 YTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILN 1584
YTGADICGFF ++EY +C RWMQLGAFYP+SRNHN TRRQDP SW+ F +SR +L
Sbjct: 1186 YTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQ 1245
Query: 1585 IRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYV 1644
RYTLLPY YT MH+ H G TV+RPLLHEF ++ TWDI QFL GPAF+V+PVLE
Sbjct: 1246 TRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNA 1305
Query: 1645 QTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSR 1704
+ V AY P ARW+DY+TG DI RG+++T A D INLHVRGG+ILP QEPA NT SR
Sbjct: 1306 RNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSR 1365
Query: 1705 QKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYI-N 1763
QK M +A DD A G LFWDDG+SIDTY + LY F+ +Q T+ S I+ YI
Sbjct: 1366 QKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITG 1425
Query: 1764 KSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIE 1823
+ +LG + +WG G+ PV +V+++ +G + FN D T +L ID+T N++L
Sbjct: 1426 TNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTS 1485
Query: 1824 INW 1826
+ W
Sbjct: 1486 LTW 1488
Score = 657 bits (1696), Expect = 0.0
Identities = 372/903 (41%), Positives = 514/903 (56%), Gaps = 57/903 (6%)
Query: 74 RINCIP-EQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAKLN- 131
+I+C P E + C RGC W N S +P+C+FV N Y+V D+ S G A ++
Sbjct: 598 KIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFV-NDLYSVSDVQYNSHGATADISL 656
Query: 132 --RIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQY-VKEFTGPTVSDT 188
+ + +N + +FKI DPNN RYEVP + T
Sbjct: 657 KSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQ 716
Query: 189 LYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKR 248
LYDV + +NPF I++ RKS G ++D+ + ++D +++ISTRLPS Y+YG GE H
Sbjct: 717 LYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTS 776
Query: 249 FRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQP 308
+R DL W TW +F+RDQ PG N+ YG ++M +E+ G + GV L+NSNAM++ QP
Sbjct: 777 YRRDLEWHTWGMFSRDQPPGYKKNS-YGVHPYYMGLEE-DGSAHGVLLLNSNAMDVTFQP 834
Query: 309 TPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVV 368
P +TYR TGG+LDFY+ LG TPE V QQY +L+G P M YW+LGFQL R+ Y++ +
Sbjct: 835 LPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEI 894
Query: 369 KEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDP 428
+ A IP+D Q +DIDYME + DFT F G P + + G + ++ILDP
Sbjct: 895 SSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILDP 953
Query: 429 AISIGRRANGT-TYATYERGNTQHVWINESDGSTPIIGEVWP------------------ 469
AIS N T Y + RG V+I + + G+VWP
Sbjct: 954 AIS----GNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVE 1009
Query: 470 ---GLTVYPDFTNPNCIDWWANECSIFH-------QEVQYDGLWIDMNEVSSFIQGS-TK 518
+PDF + WW E + + +++DG+WIDMNE SSF+ G+ +
Sbjct: 1010 LYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSP 1069
Query: 519 GCNVNKLNYPPFTP--DILDKLMYSKTICMDAVQ-----NWGKQYDVHSLYGYSMAIATE 571
GC LN+PP+ P + D+ + SKT+CM++ Q + + Y+VH+LYG+S T
Sbjct: 1070 GCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTY 1129
Query: 572 QAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVG 631
+AVQ+V +R ++TRSTF SGR A HWLGDNTA+W+Q++ SI GM+EFSLFGI G
Sbjct: 1130 EAVQEV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTG 1188
Query: 632 ADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTI 691
ADICGF + E+C RWMQLGAFYPFSRNHN+ G QDP + + V SR L
Sbjct: 1189 ADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DVAFVNISRTVLQT 1246
Query: 692 RYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGAD 751
RYTLLP+LYTL +KAH G TV RP+LHEF D +W D++FL GPA L++PVL++ A
Sbjct: 1247 RYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNAR 1306
Query: 752 TVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRK 811
V+AY P A WYDY +G R + + P D I LH+RGGYI+P QEP + T SR+
Sbjct: 1307 NVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQ 1366
Query: 812 NPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGT 871
+G +AL + TA G FWDDG++ DT G Y L +FS S NT+ ++Y GT
Sbjct: 1367 KFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGT 1426
Query: 872 T-LAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLI--ADLKLNLGRNFS 928
L ++I G+ SV V+ + M +F D + QVL I D ++L S
Sbjct: 1427 NPLKLGYIEIWGV-GSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTS 1485
Query: 929 VQW 931
+ W
Sbjct: 1486 LTW 1488
>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 714 bits (1843), Expect = 0.0
Identities = 386/931 (41%), Positives = 547/931 (58%), Gaps = 51/931 (5%)
Query: 31 LATKTPAVDEI----SDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINCIPEQFPTEG 86
L+ +P ++E S P +P P + P N R +C P++ T+
Sbjct: 42 LSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQE 101
Query: 87 ICAQRGCCWRPWNDSLI------PWCFFVDNH-GYNVQDMTTTSIGVEAKLNRIPSPTLF 139
C RGCC+ P L PWCFF ++ Y +++++++ +G A L R +PT F
Sbjct: 102 QCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRT-TPTFF 160
Query: 140 GNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPF 199
DI ++ +T NR F I DP NRRYEVP + LY V+ ++ PF
Sbjct: 161 PKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLE--TPHVHSRAPSPLYSVEFSEEPF 218
Query: 200 SIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWP 259
+ V R+ +G+ L +T++ PL ++DQ+LQ+ST LPS YI G+ E + SW
Sbjct: 219 GVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLML-STSWTRIT 277
Query: 260 IFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGG 319
++ RD P N LYG F++ +ED G + GVFL+NSNAM++ +QP+P +++R TGG
Sbjct: 278 LWNRDLAPTPGAN-LYGSHPFYLALED-GGSAHGVFLLNSNAMDVVLQPSPALSWRSTGG 335
Query: 320 ILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAG 379
ILD YI LG P+ VVQQY +VG P MP YW LGF L RW Y S + ++VV A
Sbjct: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395
Query: 380 IPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGT 439
P D Q D+DYM+ ++DFT+++ F P VQ+LH G++Y++I+DPAIS A
Sbjct: 396 FPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAG-- 453
Query: 440 TYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQY 499
+Y Y+ G + V+I G P+IG+VWPG T +PDFTNP + WW + + FH +V +
Sbjct: 454 SYRPYDEGLRRGVFITNETGQ-PLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPF 512
Query: 500 DGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVH 559
DG+WIDMNE S+FI+GS GC N+L PP+ P ++ + + TIC + Q Y++H
Sbjct: 513 DGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLH 572
Query: 560 SLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGM 619
+LYG + AIA+ +A+ K R F+++RSTFAG GR+A HW GD +SWEQ+ S+ +
Sbjct: 573 NLYGLTEAIASHRALVKA-RGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEI 631
Query: 620 LEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNS 679
L+F+L G+PLVGAD+CGF+ T+EELC RW QLGAFYPF RNHNS Q+P F + +
Sbjct: 632 LQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691
Query: 680 LLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPA 739
++ R+ LT+RY LLP LYTLF++AHV GETVARP+ EF +D+++W D + LWG A
Sbjct: 692 --QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEA 749
Query: 740 LLITPVLKQGADTVSAYIPDAIWYDYES------GAKRP-----------WRKQRVDMYL 782
LLITPVL+ G V+ Y P WYD ++ G+ P Q V +
Sbjct: 750 LLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPA 809
Query: 783 PADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQ 842
P D I +HLR GYIIP+Q P +TTT SR+ P+ L VAL + A+G+ FWDDGE+ + ++
Sbjct: 810 PLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLE 869
Query: 843 NGNYILYTFSVSNNTL--DIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN 900
G Y F NNT+ ++V S EG L Q V +LG+ + +V N P+
Sbjct: 870 RGAYTQVIFLARNNTIVNELVRVTS---EGAGLQLQKVTVLGV--ATAPQQVLSNGVPV- 923
Query: 901 AHSNFTYDASNQVLLIADLKLNLGRNFSVQW 931
SNFTY +VL I + L +G F V W
Sbjct: 924 --SNFTYSPDTKVLDIC-VSLLMGEQFLVSW 951
Score = 623 bits (1607), Expect = e-178
Identities = 354/925 (38%), Positives = 498/925 (53%), Gaps = 69/925 (7%)
Query: 862 CTHSSYQEGTTLAFQTVKILG---LTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIAD 918
C+H ++ T +LG L D + R + P+ ++ + D
Sbjct: 8 CSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRD 67
Query: 919 LKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCVW------RTGSSLSKAP 972
+ + GR +V N RF+C PD + T+++C RGC + G+ + + P
Sbjct: 68 AQAHPGRPRAVPTQCDVPPNSRFDCAPDKAI-TQEQCEARGCCYIPAKQGLQGAQMGQ-P 125
Query: 973 ECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQF 1032
C+FP SY + + S MG TA L T P D I TLR++V + L F
Sbjct: 126 WCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHF 181
Query: 1033 KIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPG 1092
I DP +RYEVP L P S LY VE E PFG+ +RR+ GRV+ ++ +
Sbjct: 182 TIKDPANRRYEVP--LETPHVH-SRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAP 238
Query: 1093 FAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPY 1152
F DQF+Q+ST LPS+YI G E + +W ++ RD P N YG HP+
Sbjct: 239 LFFADQFLQLSTSLPSQYITGLAE-HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPF 297
Query: 1153 YMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEV 1212
Y+ALE+ G+AHGVFLLNSNAMDV QP+PAL++R+ GGILD Y+FLGP P+ +QY +V
Sbjct: 298 YLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDV 357
Query: 1213 IGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIG 1272
+G+P MP YW LGF LCR+GY++T+ R++ + M A+ P DVQ+ D+DYM+ + DFT
Sbjct: 358 VGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFN 417
Query: 1273 -EAFQDLPQFVDKIRGEGMRYIIILDPAISGN-ETKTYPAFERGQQNDVFVKWPNTNDIC 1330
+ F+D P V ++ G RY++I+DPAIS + +Y ++ G + VF+ T
Sbjct: 418 KDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFIT-NETGQPL 476
Query: 1331 WAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDG 1390
KVWP AFPDF + WW + +F+++ + FDG
Sbjct: 477 IGKVWP---------------------GSTAFPDFTNPTALAWWEDMVAEFHDQ-VPFDG 514
Query: 1391 LWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSV 1450
+WIDMNEPS+F+ G+ C N+EL PPY P + T L TIC + Q LS
Sbjct: 515 MWIDMNEPSNFIRGSEDG-CPNNELENPPYVPGVVGGT--LQAATICASSHQFLST---- 567
Query: 1451 LHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDK 1510
HY++HNLYG ++ +H AL K G R VISRST+ GR+ GHW GD ++ W+ +
Sbjct: 568 -HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLAS 626
Query: 1511 SIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPAS 1570
S+ +++F+L G+ GAD+CGF N+ LC RW QLGAFYP+ RNHN + Q+P S
Sbjct: 627 SVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYS 686
Query: 1571 WNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLW 1630
++E + R L +RY LLP+ YT H+ H G TV RPL EF + TW + Q LW
Sbjct: 687 FSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLW 746
Query: 1631 GPAFMVTPVLEPYVQTVNAYVPNARWFDYHT-----------------GKDIGVRGQFQT 1673
G A ++TPVL+ V Y P W+D T I GQ+ T
Sbjct: 747 GEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVT 806
Query: 1674 FNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESID 1733
A DTIN+H+R G+I+P Q P T SRQ+ M L VA A+G LFWDDGES++
Sbjct: 807 LPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLE 866
Query: 1734 TYERDLYLSVQFNLNQTTLTSTILK 1758
ER Y V F T+ + +++
Sbjct: 867 VLERGAYTQVIFLARNNTIVNELVR 891
>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 714 bits (1843), Expect = 0.0
Identities = 386/931 (41%), Positives = 547/931 (58%), Gaps = 51/931 (5%)
Query: 31 LATKTPAVDEI----SDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINCIPEQFPTEG 86
L+ +P ++E S P +P P + P N R +C P++ T+
Sbjct: 42 LSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQE 101
Query: 87 ICAQRGCCWRPWNDSLI------PWCFFVDNH-GYNVQDMTTTSIGVEAKLNRIPSPTLF 139
C RGCC+ P L PWCFF ++ Y +++++++ +G A L R +PT F
Sbjct: 102 QCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRT-TPTFF 160
Query: 140 GNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPF 199
DI ++ +T NR F I DP NRRYEVP + LY V+ ++ PF
Sbjct: 161 PKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLE--TPHVHSRAPSPLYSVEFSEEPF 218
Query: 200 SIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWP 259
+ V R+ +G+ L +T++ PL ++DQ+LQ+ST LPS YI G+ E + SW
Sbjct: 219 GVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLML-STSWTRIT 277
Query: 260 IFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGG 319
++ RD P N LYG F++ +ED G + GVFL+NSNAM++ +QP+P +++R TGG
Sbjct: 278 LWNRDLAPTPGAN-LYGSHPFYLALED-GGSAHGVFLLNSNAMDVVLQPSPALSWRSTGG 335
Query: 320 ILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAG 379
ILD YI LG P+ VVQQY +VG P MP YW LGF L RW Y S + ++VV A
Sbjct: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395
Query: 380 IPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGT 439
P D Q D+DYM+ ++DFT+++ F P VQ+LH G++Y++I+DPAIS A
Sbjct: 396 FPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAG-- 453
Query: 440 TYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQY 499
+Y Y+ G + V+I G P+IG+VWPG T +PDFTNP + WW + + FH +V +
Sbjct: 454 SYRPYDEGLRRGVFITNETGQ-PLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPF 512
Query: 500 DGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVH 559
DG+WIDMNE S+FI+GS GC N+L PP+ P ++ + + TIC + Q Y++H
Sbjct: 513 DGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLH 572
Query: 560 SLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGM 619
+LYG + AIA+ +A+ K R F+++RSTFAG GR+A HW GD +SWEQ+ S+ +
Sbjct: 573 NLYGLTEAIASHRALVKA-RGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEI 631
Query: 620 LEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNS 679
L+F+L G+PLVGAD+CGF+ T+EELC RW QLGAFYPF RNHNS Q+P F + +
Sbjct: 632 LQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691
Query: 680 LLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPA 739
++ R+ LT+RY LLP LYTLF++AHV GETVARP+ EF +D+++W D + LWG A
Sbjct: 692 --QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEA 749
Query: 740 LLITPVLKQGADTVSAYIPDAIWYDYES------GAKRP-----------WRKQRVDMYL 782
LLITPVL+ G V+ Y P WYD ++ G+ P Q V +
Sbjct: 750 LLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPA 809
Query: 783 PADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQ 842
P D I +HLR GYIIP+Q P +TTT SR+ P+ L VAL + A+G+ FWDDGE+ + ++
Sbjct: 810 PLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLE 869
Query: 843 NGNYILYTFSVSNNTL--DIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN 900
G Y F NNT+ ++V S EG L Q V +LG+ + +V N P+
Sbjct: 870 RGAYTQVIFLARNNTIVNELVRVTS---EGAGLQLQKVTVLGV--ATAPQQVLSNGVPV- 923
Query: 901 AHSNFTYDASNQVLLIADLKLNLGRNFSVQW 931
SNFTY +VL I + L +G F V W
Sbjct: 924 --SNFTYSPDTKVLDIC-VSLLMGEQFLVSW 951
Score = 623 bits (1607), Expect = e-178
Identities = 354/925 (38%), Positives = 498/925 (53%), Gaps = 69/925 (7%)
Query: 862 CTHSSYQEGTTLAFQTVKILG---LTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIAD 918
C+H ++ T +LG L D + R + P+ ++ + D
Sbjct: 8 CSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRD 67
Query: 919 LKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCVW------RTGSSLSKAP 972
+ + GR +V N RF+C PD + T+++C RGC + G+ + + P
Sbjct: 68 AQAHPGRPRAVPTQCDVPPNSRFDCAPDKAI-TQEQCEARGCCYIPAKQGLQGAQMGQ-P 125
Query: 973 ECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQF 1032
C+FP SY + + S MG TA L T P D I TLR++V + L F
Sbjct: 126 WCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHF 181
Query: 1033 KIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPG 1092
I DP +RYEVP L P S LY VE E PFG+ +RR+ GRV+ ++ +
Sbjct: 182 TIKDPANRRYEVP--LETPHVH-SRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAP 238
Query: 1093 FAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPY 1152
F DQF+Q+ST LPS+YI G E + +W ++ RD P N YG HP+
Sbjct: 239 LFFADQFLQLSTSLPSQYITGLAE-HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPF 297
Query: 1153 YMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEV 1212
Y+ALE+ G+AHGVFLLNSNAMDV QP+PAL++R+ GGILD Y+FLGP P+ +QY +V
Sbjct: 298 YLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDV 357
Query: 1213 IGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIG 1272
+G+P MP YW LGF LCR+GY++T+ R++ + M A+ P DVQ+ D+DYM+ + DFT
Sbjct: 358 VGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFN 417
Query: 1273 -EAFQDLPQFVDKIRGEGMRYIIILDPAISGN-ETKTYPAFERGQQNDVFVKWPNTNDIC 1330
+ F+D P V ++ G RY++I+DPAIS + +Y ++ G + VF+ T
Sbjct: 418 KDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFIT-NETGQPL 476
Query: 1331 WAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDG 1390
KVWP AFPDF + WW + +F+++ + FDG
Sbjct: 477 IGKVWP---------------------GSTAFPDFTNPTALAWWEDMVAEFHDQ-VPFDG 514
Query: 1391 LWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSV 1450
+WIDMNEPS+F+ G+ C N+EL PPY P + T L TIC + Q LS
Sbjct: 515 MWIDMNEPSNFIRGSEDG-CPNNELENPPYVPGVVGGT--LQAATICASSHQFLST---- 567
Query: 1451 LHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDK 1510
HY++HNLYG ++ +H AL K G R VISRST+ GR+ GHW GD ++ W+ +
Sbjct: 568 -HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLAS 626
Query: 1511 SIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPAS 1570
S+ +++F+L G+ GAD+CGF N+ LC RW QLGAFYP+ RNHN + Q+P S
Sbjct: 627 SVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYS 686
Query: 1571 WNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLW 1630
++E + R L +RY LLP+ YT H+ H G TV RPL EF + TW + Q LW
Sbjct: 687 FSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLW 746
Query: 1631 GPAFMVTPVLEPYVQTVNAYVPNARWFDYHT-----------------GKDIGVRGQFQT 1673
G A ++TPVL+ V Y P W+D T I GQ+ T
Sbjct: 747 GEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVT 806
Query: 1674 FNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESID 1733
A DTIN+H+R G+I+P Q P T SRQ+ M L VA A+G LFWDDGES++
Sbjct: 807 LPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLE 866
Query: 1734 TYERDLYLSVQFNLNQTTLTSTILK 1758
ER Y V F T+ + +++
Sbjct: 867 VLERGAYTQVIFLARNNTIVNELVR 891
>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 714 bits (1843), Expect = 0.0
Identities = 386/931 (41%), Positives = 547/931 (58%), Gaps = 51/931 (5%)
Query: 31 LATKTPAVDEI----SDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINCIPEQFPTEG 86
L+ +P ++E S P +P P + P N R +C P++ T+
Sbjct: 42 LSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQE 101
Query: 87 ICAQRGCCWRPWNDSLI------PWCFFVDNH-GYNVQDMTTTSIGVEAKLNRIPSPTLF 139
C RGCC+ P L PWCFF ++ Y +++++++ +G A L R +PT F
Sbjct: 102 QCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRT-TPTFF 160
Query: 140 GNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPF 199
DI ++ +T NR F I DP NRRYEVP + LY V+ ++ PF
Sbjct: 161 PKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLE--TPHVHSRAPSPLYSVEFSEEPF 218
Query: 200 SIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWP 259
+ V R+ +G+ L +T++ PL ++DQ+LQ+ST LPS YI G+ E + SW
Sbjct: 219 GVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLML-STSWTRIT 277
Query: 260 IFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGG 319
++ RD P N LYG F++ +ED G + GVFL+NSNAM++ +QP+P +++R TGG
Sbjct: 278 LWNRDLAPTPGAN-LYGSHPFYLALED-GGSAHGVFLLNSNAMDVVLQPSPALSWRSTGG 335
Query: 320 ILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAG 379
ILD YI LG P+ VVQQY +VG P MP YW LGF L RW Y S + ++VV A
Sbjct: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395
Query: 380 IPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGT 439
P D Q D+DYM+ ++DFT+++ F P VQ+LH G++Y++I+DPAIS A
Sbjct: 396 FPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAG-- 453
Query: 440 TYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQY 499
+Y Y+ G + V+I G P+IG+VWPG T +PDFTNP + WW + + FH +V +
Sbjct: 454 SYRPYDEGLRRGVFITNETGQ-PLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPF 512
Query: 500 DGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVH 559
DG+WIDMNE S+FI+GS GC N+L PP+ P ++ + + TIC + Q Y++H
Sbjct: 513 DGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLH 572
Query: 560 SLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGM 619
+LYG + AIA+ +A+ K R F+++RSTFAG GR+A HW GD +SWEQ+ S+ +
Sbjct: 573 NLYGLTEAIASHRALVKA-RGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEI 631
Query: 620 LEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNS 679
L+F+L G+PLVGAD+CGF+ T+EELC RW QLGAFYPF RNHNS Q+P F + +
Sbjct: 632 LQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691
Query: 680 LLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPA 739
++ R+ LT+RY LLP LYTLF++AHV GETVARP+ EF +D+++W D + LWG A
Sbjct: 692 --QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEA 749
Query: 740 LLITPVLKQGADTVSAYIPDAIWYDYES------GAKRP-----------WRKQRVDMYL 782
LLITPVL+ G V+ Y P WYD ++ G+ P Q V +
Sbjct: 750 LLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPA 809
Query: 783 PADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQ 842
P D I +HLR GYIIP+Q P +TTT SR+ P+ L VAL + A+G+ FWDDGE+ + ++
Sbjct: 810 PLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLE 869
Query: 843 NGNYILYTFSVSNNTL--DIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN 900
G Y F NNT+ ++V S EG L Q V +LG+ + +V N P+
Sbjct: 870 RGAYTQVIFLARNNTIVNELVRVTS---EGAGLQLQKVTVLGV--ATAPQQVLSNGVPV- 923
Query: 901 AHSNFTYDASNQVLLIADLKLNLGRNFSVQW 931
SNFTY +VL I + L +G F V W
Sbjct: 924 --SNFTYSPDTKVLDIC-VSLLMGEQFLVSW 951
Score = 623 bits (1607), Expect = e-178
Identities = 354/925 (38%), Positives = 498/925 (53%), Gaps = 69/925 (7%)
Query: 862 CTHSSYQEGTTLAFQTVKILG---LTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIAD 918
C+H ++ T +LG L D + R + P+ ++ + D
Sbjct: 8 CSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRD 67
Query: 919 LKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCVW------RTGSSLSKAP 972
+ + GR +V N RF+C PD + T+++C RGC + G+ + + P
Sbjct: 68 AQAHPGRPRAVPTQCDVPPNSRFDCAPDKAI-TQEQCEARGCCYIPAKQGLQGAQMGQ-P 125
Query: 973 ECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQF 1032
C+FP SY + + S MG TA L T P D I TLR++V + L F
Sbjct: 126 WCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHF 181
Query: 1033 KIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPG 1092
I DP +RYEVP L P S LY VE E PFG+ +RR+ GRV+ ++ +
Sbjct: 182 TIKDPANRRYEVP--LETPHVH-SRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAP 238
Query: 1093 FAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPY 1152
F DQF+Q+ST LPS+YI G E + +W ++ RD P N YG HP+
Sbjct: 239 LFFADQFLQLSTSLPSQYITGLAE-HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPF 297
Query: 1153 YMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEV 1212
Y+ALE+ G+AHGVFLLNSNAMDV QP+PAL++R+ GGILD Y+FLGP P+ +QY +V
Sbjct: 298 YLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDV 357
Query: 1213 IGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIG 1272
+G+P MP YW LGF LCR+GY++T+ R++ + M A+ P DVQ+ D+DYM+ + DFT
Sbjct: 358 VGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFN 417
Query: 1273 -EAFQDLPQFVDKIRGEGMRYIIILDPAISGN-ETKTYPAFERGQQNDVFVKWPNTNDIC 1330
+ F+D P V ++ G RY++I+DPAIS + +Y ++ G + VF+ T
Sbjct: 418 KDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFIT-NETGQPL 476
Query: 1331 WAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDG 1390
KVWP AFPDF + WW + +F+++ + FDG
Sbjct: 477 IGKVWP---------------------GSTAFPDFTNPTALAWWEDMVAEFHDQ-VPFDG 514
Query: 1391 LWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSV 1450
+WIDMNEPS+F+ G+ C N+EL PPY P + T L TIC + Q LS
Sbjct: 515 MWIDMNEPSNFIRGSEDG-CPNNELENPPYVPGVVGGT--LQAATICASSHQFLST---- 567
Query: 1451 LHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDK 1510
HY++HNLYG ++ +H AL K G R VISRST+ GR+ GHW GD ++ W+ +
Sbjct: 568 -HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLAS 626
Query: 1511 SIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPAS 1570
S+ +++F+L G+ GAD+CGF N+ LC RW QLGAFYP+ RNHN + Q+P S
Sbjct: 627 SVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYS 686
Query: 1571 WNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLW 1630
++E + R L +RY LLP+ YT H+ H G TV RPL EF + TW + Q LW
Sbjct: 687 FSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLW 746
Query: 1631 GPAFMVTPVLEPYVQTVNAYVPNARWFDYHT-----------------GKDIGVRGQFQT 1673
G A ++TPVL+ V Y P W+D T I GQ+ T
Sbjct: 747 GEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVT 806
Query: 1674 FNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESID 1733
A DTIN+H+R G+I+P Q P T SRQ+ M L VA A+G LFWDDGES++
Sbjct: 807 LPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLE 866
Query: 1734 TYERDLYLSVQFNLNQTTLTSTILK 1758
ER Y V F T+ + +++
Sbjct: 867 VLERGAYTQVIFLARNNTIVNELVR 891
>gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
Length = 914
Score = 298 bits (763), Expect = 3e-80
Identities = 205/674 (30%), Positives = 324/674 (48%), Gaps = 70/674 (10%)
Query: 289 GKSFGVFLMNSNAMEIFIQPTPIVTYRVT----------------------GGILDFYIL 326
G++ G+F +N++ + I P V Y +T GI+D ++L
Sbjct: 277 GRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLL 336
Query: 327 LGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQV 386
G TP V +QY L G AMP ++LG+ RWNY+ VK V E IP+D
Sbjct: 337 TGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMW 396
Query: 387 TDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYER 446
DI++ E K+ FT+D+ F + + L +K V+I DP I I Y+ Y +
Sbjct: 397 LDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKID-----PDYSVYVK 451
Query: 447 GNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECS--IFHQEVQYDGLWI 504
Q ++ +G G WPGL+ Y DFTNP +W+++ + ++ LW
Sbjct: 452 AKDQGFFVKNQEGED-FEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWN 510
Query: 505 DMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGY 564
DMNE S F +G + N +++ NW + ++H++YG+
Sbjct: 511 DMNEPSVF-RGPEQTMQKNAIHHG----------------------NW-EHRELHNIYGF 546
Query: 565 SMAIATEQAVQKVFPNK-RSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFS 623
+AT + + K K R F+LTRS FAGS ++ A W GDNTA W ++ SI +L S
Sbjct: 547 YHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLS 606
Query: 624 LFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVK 683
+ GI GADI GF+ EL RW Q GA+ PF R H + + ++P FG+ +
Sbjct: 607 ITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEH--TR 664
Query: 684 SSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLIT 743
R+ + RY LLP+ Y+LFY AHV + V RP+ EF ++ ++ + E++ G ALL+
Sbjct: 665 LIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVH 724
Query: 744 PVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQ-RVDMYLPADKIGLHLRGGYIIPIQ 800
PV + A TV ++P + +WYDY++ A W V + + D I + RGG +IPI+
Sbjct: 725 PVTEPKATTVDVFLPGSNEVWYDYKTFAH--WEGGCTVKIPVALDTIPVFQRGGSVIPIK 782
Query: 801 EPDVTTTA-SRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLD 859
+T ++ GL VAL ++ G+ + DDG + + ++ FS ++ L
Sbjct: 783 TTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLI 842
Query: 860 IVCTHSSYQEGTTLAFQTVKILGL---TDSVTEVRVAENNQPMNAHSNFTYDASNQVLLI 916
+ + + +LG SVT +QP+ FTY A +L +
Sbjct: 843 NSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPV----AFTYCAKTSILSL 898
Query: 917 ADLKLNLGRNFSVQ 930
L LN+ ++ V+
Sbjct: 899 EKLSLNIATDWEVR 912
Score = 259 bits (663), Expect = 1e-68
Identities = 210/815 (25%), Positives = 347/815 (42%), Gaps = 116/815 (14%)
Query: 1049 NIPTTPISTYEDRLYDVEIKENPFG--IQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRL 1106
N T + T ++ D+ + E FG + I+ + D L GF
Sbjct: 176 NEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGF------------- 222
Query: 1107 PSEYIYGFGE-VEHTAFKRDLNWNTWGMFTRDQPPGY----KLNSYGFHPYYMALEEEGN 1161
E++YG + E K + + + ++ D GY K+ YG PY +A + G
Sbjct: 223 --EHLYGIPQHAESHQLKNTGDGDAYRLYNLDVY-GYQIYDKMGIYGSVPYLLA-HKLGR 278
Query: 1162 AHGVFLLNSNAMDVTFQPTPALTYRTV----------------------GGILDFYMFLG 1199
G+F LN++ V PA+ Y GI+D ++ G
Sbjct: 279 TIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTG 338
Query: 1200 PTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTD 1259
PTP KQY + G MP ++LG+ CR+ Y + +V+ + +IPYD + D
Sbjct: 339 PTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLD 398
Query: 1260 IDYMERQLDFTIGE-AFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQND 1318
I++ E + FT + F + + + +R + + ++I DP I + Y + + +
Sbjct: 399 IEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKID--PDYSVYVKAKDQG 456
Query: 1319 VFVKWPNTND---ICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWA 1375
FVK D +CW P ++ ++ DF EW++
Sbjct: 457 FFVKNQEGEDFEGVCW-------PGLS------------------SYLDFTNPKVREWYS 491
Query: 1376 REIV-DFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFR 1434
Y LW DMNEPS F PE T + + +H
Sbjct: 492 SLFAFPVYQGSTDILFLWNDMNEPSVFRG------------------PEQTMQKNAIHH- 532
Query: 1435 TICMEAEQILSDGTSVLHYDVHNLYG-WSQMKPTHDALQKTTGK-RGIVISRSTYPTSGR 1492
+ H ++HN+YG + QM ++++ GK R V++RS + S +
Sbjct: 533 -------------GNWEHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQK 579
Query: 1493 WGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFY 1552
+G W GDN A W N+ SI ++ S+ G+S+ GADI GF N E L RW Q GA+
Sbjct: 580 YGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQ 639
Query: 1553 PYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLL 1612
P+ R H NT+R++P + E + R + RY LLPY+Y+ + H V+RPL
Sbjct: 640 PFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLW 699
Query: 1613 HEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVP--NARWFDYHTGKDIGVRGQ 1670
EF DE T+D+ +++ G A +V PV EP TV+ ++P N W+DY T G
Sbjct: 700 VEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAH-WEGGC 758
Query: 1671 FQTFNASYDTINLHVRGGHILPCQEP-AQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDG 1729
+ DTI + RGG ++P + ++T + + L VA + G L+ DDG
Sbjct: 759 TVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDG 818
Query: 1730 ESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTY 1789
S + +L +F+ + L ++ + S+ + + V G P + T +
Sbjct: 819 HSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSS 878
Query: 1790 NGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEI 1824
+G + F IL ++ + N+ + + I
Sbjct: 879 DGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRI 913
>gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens]
Length = 966
Score = 277 bits (709), Expect = 6e-74
Identities = 205/635 (32%), Positives = 305/635 (48%), Gaps = 55/635 (8%)
Query: 308 PTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDV 367
P V + GI+D ++LLG + V +QY L G A+P ++LG+ SRWNY+
Sbjct: 371 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 430
Query: 368 VKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILD 427
V EV + + +P D DI++ + K+ FT+D F ++ L +K V I+D
Sbjct: 431 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 490
Query: 428 PAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWA 487
P I + + Y +E +++ DGS G WPG YPDFTNP WWA
Sbjct: 491 PHIKVD-----SGYRVHEELRNLGLYVKTRDGSD-YEGWCWPGSAGYPDFTNPTMRAWWA 544
Query: 488 NECSIFHQEVQYDGL--WIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTIC 545
N S + E L W DMNE S F N P T +
Sbjct: 545 NMFSYDNYEGSAPNLFVWNDMNEPSVF-------------NGPEVT------------ML 579
Query: 546 MDAVQNWGKQY-DVHSLYGYSMAIATEQAV-QKVFPNKRSFILTRSTFAGSGRHAAHWLG 603
DA G ++ DVH++YG + +AT + Q+ +R F+L R+ FAGS R A W G
Sbjct: 580 KDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTG 639
Query: 604 DNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHN 663
DNTA W+ ++ SI L L G+ GAD+ GF EL RW Q+GA+ PF R H
Sbjct: 640 DNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHA 699
Query: 664 SDGYEHQDPAFF-GQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFY 722
++P Q++ ++ R L RY+LLPF YTL Y+AH G V RP+ ++
Sbjct: 700 HLDTGRREPWLLPSQHNDII---RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYP 756
Query: 723 EDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQRVDM 780
+D ++ D ++L G ALL+ PV GA V Y+P +WYD +S K + +
Sbjct: 757 QDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQ---TL 813
Query: 781 YLPA--DKIGLHLRGGYIIP-IQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGET 837
YLP I + RGG I+P ++ + +P+ L VAL TA+G+ F DDG T
Sbjct: 814 YLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHT 873
Query: 838 KDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEG---TTLAFQTVKILGLTDSVTEVRVAE 894
+ ++L FS S NTL + S+ EG T + + V I+G V +
Sbjct: 874 FNYQTRQEFLLRRFSFSGNTL---VSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTK 930
Query: 895 NNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSV 929
+ + +F +D VL++ +N+ ++S+
Sbjct: 931 GSP--ESRLSFQHDPETSVLVLRKPGINVASDWSI 963
Score = 221 bits (563), Expect = 5e-57
Identities = 176/657 (26%), Positives = 292/657 (44%), Gaps = 73/657 (11%)
Query: 1179 PTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSE 1238
P + + + GI+D ++ LGP+ +QY + G +P ++LG+ R+ Y + ++
Sbjct: 371 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 430
Query: 1239 VRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQ-FVDKIRGEGMRYIIILD 1297
V E+ N+P DV + DI++ + + FT + P+ ++++ + + + I+D
Sbjct: 431 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 490
Query: 1298 PAISGNETKTYPAFERGQQNDVFVKWPNTNDI---CWAKVWPDLPNITIDKTLTEDEAVN 1354
P I + Y E + ++VK + +D CW
Sbjct: 491 PHIKVDSG--YRVHEELRNLGLYVKTRDGSDYEGWCWP---------------------- 526
Query: 1355 ASRAHVAFPDFFRTSTAEWWAREI-VDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRND 1413
+PDF + WWA D Y +W DMNEPS F NG
Sbjct: 527 ---GSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVF-NG--------- 573
Query: 1414 ELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQK 1473
PE+T D H+ H DVHN+YG T D L++
Sbjct: 574 --------PEVTMLKDAQHYG--------------GWEHRDVHNIYGLYVHMATADGLRQ 611
Query: 1474 TTG--KRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADIC 1531
+G +R V++R+ + S R+G W GDN A WD++ SI + L G+S+ GAD+
Sbjct: 612 RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 671
Query: 1532 GFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLP 1591
GFF N E L RW Q+GA+ P+ R H +T R++P ++ R+ L RY+LLP
Sbjct: 672 GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 731
Query: 1592 YFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYV 1651
++YT +++ H G V+RPL ++ + T++I Q+L G A +V PV + V Y+
Sbjct: 732 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 791
Query: 1652 PNAR--WFDYHT-GKDIGVRGQFQTFNASYDTINLHVRGGHILP-CQEPAQNTFYSRQKH 1707
P W+D + K G + + S +I + RGG I+P +++ +
Sbjct: 792 PGQGEVWYDIQSYQKHHGPQTLYLPVTLS--SIPVFQRGGTIVPRWMRVRRSSECMKDDP 849
Query: 1708 MKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSET 1767
+ L VA AQG LF DDG + + R +L +F+ + TL S+ ++
Sbjct: 850 ITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPI 909
Query: 1768 RLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEI 1824
+ + + G G P V T ++ L F D +L + NV + I +
Sbjct: 910 WIERVVIIGAG-KPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHL 965
>gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens]
Length = 944
Score = 277 bits (709), Expect = 6e-74
Identities = 205/635 (32%), Positives = 305/635 (48%), Gaps = 55/635 (8%)
Query: 308 PTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDV 367
P V + GI+D ++LLG + V +QY L G A+P ++LG+ SRWNY+
Sbjct: 349 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
Query: 368 VKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILD 427
V EV + + +P D DI++ + K+ FT+D F ++ L +K V I+D
Sbjct: 409 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
Query: 428 PAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWA 487
P I + + Y +E +++ DGS G WPG YPDFTNP WWA
Sbjct: 469 PHIKVD-----SGYRVHEELRNLGLYVKTRDGSD-YEGWCWPGSAGYPDFTNPTMRAWWA 522
Query: 488 NECSIFHQEVQYDGL--WIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTIC 545
N S + E L W DMNE S F N P T +
Sbjct: 523 NMFSYDNYEGSAPNLFVWNDMNEPSVF-------------NGPEVT------------ML 557
Query: 546 MDAVQNWGKQY-DVHSLYGYSMAIATEQAV-QKVFPNKRSFILTRSTFAGSGRHAAHWLG 603
DA G ++ DVH++YG + +AT + Q+ +R F+L R+ FAGS R A W G
Sbjct: 558 KDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTG 617
Query: 604 DNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHN 663
DNTA W+ ++ SI L L G+ GAD+ GF EL RW Q+GA+ PF R H
Sbjct: 618 DNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHA 677
Query: 664 SDGYEHQDPAFF-GQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFY 722
++P Q++ ++ R L RY+LLPF YTL Y+AH G V RP+ ++
Sbjct: 678 HLDTGRREPWLLPSQHNDII---RDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYP 734
Query: 723 EDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQRVDM 780
+D ++ D ++L G ALL+ PV GA V Y+P +WYD +S K + +
Sbjct: 735 QDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQ---TL 791
Query: 781 YLPA--DKIGLHLRGGYIIP-IQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGET 837
YLP I + RGG I+P ++ + +P+ L VAL TA+G+ F DDG T
Sbjct: 792 YLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHT 851
Query: 838 KDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEG---TTLAFQTVKILGLTDSVTEVRVAE 894
+ ++L FS S NTL + S+ EG T + + V I+G V +
Sbjct: 852 FNYQTRQEFLLRRFSFSGNTL---VSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTK 908
Query: 895 NNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSV 929
+ + +F +D VL++ +N+ ++S+
Sbjct: 909 GSP--ESRLSFQHDPETSVLVLRKPGINVASDWSI 941
Score = 221 bits (563), Expect = 5e-57
Identities = 176/657 (26%), Positives = 292/657 (44%), Gaps = 73/657 (11%)
Query: 1179 PTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSE 1238
P + + + GI+D ++ LGP+ +QY + G +P ++LG+ R+ Y + ++
Sbjct: 349 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
Query: 1239 VRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQ-FVDKIRGEGMRYIIILD 1297
V E+ N+P DV + DI++ + + FT + P+ ++++ + + + I+D
Sbjct: 409 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
Query: 1298 PAISGNETKTYPAFERGQQNDVFVKWPNTNDI---CWAKVWPDLPNITIDKTLTEDEAVN 1354
P I + Y E + ++VK + +D CW
Sbjct: 469 PHIKVDSG--YRVHEELRNLGLYVKTRDGSDYEGWCWP---------------------- 504
Query: 1355 ASRAHVAFPDFFRTSTAEWWAREI-VDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRND 1413
+PDF + WWA D Y +W DMNEPS F NG
Sbjct: 505 ---GSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVF-NG--------- 551
Query: 1414 ELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQK 1473
PE+T D H+ H DVHN+YG T D L++
Sbjct: 552 --------PEVTMLKDAQHYG--------------GWEHRDVHNIYGLYVHMATADGLRQ 589
Query: 1474 TTG--KRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADIC 1531
+G +R V++R+ + S R+G W GDN A WD++ SI + L G+S+ GAD+
Sbjct: 590 RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 649
Query: 1532 GFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLP 1591
GFF N E L RW Q+GA+ P+ R H +T R++P ++ R+ L RY+LLP
Sbjct: 650 GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 709
Query: 1592 YFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYV 1651
++YT +++ H G V+RPL ++ + T++I Q+L G A +V PV + V Y+
Sbjct: 710 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 769
Query: 1652 PNAR--WFDYHT-GKDIGVRGQFQTFNASYDTINLHVRGGHILP-CQEPAQNTFYSRQKH 1707
P W+D + K G + + S +I + RGG I+P +++ +
Sbjct: 770 PGQGEVWYDIQSYQKHHGPQTLYLPVTLS--SIPVFQRGGTIVPRWMRVRRSSECMKDDP 827
Query: 1708 MKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSET 1767
+ L VA AQG LF DDG + + R +L +F+ + TL S+ ++
Sbjct: 828 ITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPI 887
Query: 1768 RLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEI 1824
+ + + G G P V T ++ L F D +L + NV + I +
Sbjct: 888 WIERVVIIGAG-KPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHL 943
>gi|153791946 hypothetical protein LOC57462 [Homo sapiens]
Length = 714
Score = 64.3 bits (155), Expect = 1e-09
Identities = 87/400 (21%), Positives = 146/400 (36%), Gaps = 73/400 (18%)
Query: 382 FDTQVTDID--YMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGT 439
F++ +ID Y DF +D+V F + L D G + + + P ++ G
Sbjct: 345 FNSSHLEIDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVNYNSSRFG- 403
Query: 440 TYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQY 499
G + +++ E G P + W G+ DFT+P DW+
Sbjct: 404 ------EGVERELFVREPTGRLPALVRWWNGIGAVLDFTHPKARDWFQGHLRRLRSRYSV 457
Query: 500 DGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVH 559
D EVS + + Y P PD W ++Y
Sbjct: 458 ASFKFDAGEVSYLPRDFS--------TYRPL-PD---------------PSVWSRRYTEM 493
Query: 560 SLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQ---MEWSI 616
+L +S+A E V N F L D + W + I
Sbjct: 494 ALPFFSLA---EVRVGYQSQNISCFFR---------------LVDRDSVWGYDLGLRSLI 535
Query: 617 TGMLEFSLFGIPLVGADICG--FVAETT-------EELCRRWMQLGAFYPFSRNHNSDGY 667
+L S+ G P + D+ G V + T EL RW+++ AF P
Sbjct: 536 PAVLTVSMLGYPFILPDMVGGNAVPQRTAGGDVPERELYIRWLEVAAFMP--------AM 587
Query: 668 EHQDPAFFGQNSLLVKSSRQYLTIRYTLL-PFLYTLFYKAHVFGETVARPVLHEFYEDTN 726
+ P + ++ +V ++++ +R +L+ P L L + G+ + RP+ D
Sbjct: 588 QFSIPPW-RYDAEVVAIAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDET 646
Query: 727 SWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYE 766
+ D++FL G LL+ PVL+ G Y+P W Y+
Sbjct: 647 AHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYK 686
Score = 46.2 bits (108), Expect = 3e-04
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 1538 EYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLL-PYFYTQ 1596
E L RW+++ AF P A P ++ +++ +R +L+ P
Sbjct: 570 ERELYIRWLEVAAFMP-------AMQFSIPPWRYDAEVVAIAQKFAALRASLVAPLLLEL 622
Query: 1597 MHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARW 1656
E+ G ++RPL ++ I QFL G +V PVLEP Q + Y+P +W
Sbjct: 623 AGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKW 682
Query: 1657 FDY 1659
Y
Sbjct: 683 RSY 685
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/47 (36%), Positives = 31/47 (65%)
Query: 3 RKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPA 49
+++++ LEISL VL +++TIIA+ +I + AT + + SD + A
Sbjct: 21 KQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAA 67
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/47 (36%), Positives = 31/47 (65%)
Query: 3 RKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPA 49
+++++ LEISL VL +++TIIA+ +I + AT + + SD + A
Sbjct: 21 KQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAA 67
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/47 (36%), Positives = 31/47 (65%)
Query: 3 RKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPA 49
+++++ LEISL VL +++TIIA+ +I + AT + + SD + A
Sbjct: 21 KQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAA 67
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 1.1
Identities = 17/47 (36%), Positives = 31/47 (65%)
Query: 3 RKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPA 49
+++++ LEISL VL +++TIIA+ +I + AT + + SD + A
Sbjct: 21 KQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAA 67
>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
Length = 742
Score = 32.7 bits (73), Expect = 3.3
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 794 GYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSV 853
G+++P E D+ + S K LGLIV LG G F W G D + +L + SV
Sbjct: 187 GFVLPSAEKDMCLSDSNKGMLGLIVYLG---MMVGAFLW--GGLADRLGRRQCLLISLSV 241
Query: 854 SNNTLDIVCTHSSYQEG 870
++ + SS+ +G
Sbjct: 242 NS----VFAFFSSFVQG 254
>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
Length = 334
Score = 32.7 bits (73), Expect = 3.3
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 615 SITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYE 668
S+ G + L PL A G +A +EL R++ AF P+SR +N +G E
Sbjct: 279 SLLGSVASRLSSAPLTMA---GSLAGNLQELSARYLSSSAFEPYSRTNNKEGAE 329
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 32.3 bits (72), Expect = 4.3
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 29/154 (18%)
Query: 551 NWGKQYDVHSLYGYSMAIATE-------QAVQKVFPNKRSFILTRSTFAG---------S 594
N+G + + ++Y IA + + F N+ ++L ST G +
Sbjct: 119 NYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNA 178
Query: 595 GRHAAHWLGDNTASWE--------QMEWSITGMLE-FSLFGIPLVGADICGFVAETTEEL 645
G H+ W+ TA W Q + +IT +LE +F +P+ D G+V T+
Sbjct: 179 GIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPD--GYVYTQTQN- 235
Query: 646 CRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNS 679
R W + + P S +D + + +F G+ +
Sbjct: 236 -RLWRKTRSRNPGSSCIGADPNRNWNASFAGKGA 268
>gi|221307475 N-acylsphingosine amidohydrolase 2 isoform b [Homo
sapiens]
Length = 745
Score = 32.3 bits (72), Expect = 4.3
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 1 MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISD-------STSTPATTRV 53
MA++ FS LE LI L V+++ I +AL+ +L + ++ D +T +P T+
Sbjct: 1 MAKRTFSNLETFLIFLLVMMSAITVALLSLLFITSGTIENHKDLGGHFFSTTQSPPATQG 60
Query: 54 TT 55
+T
Sbjct: 61 ST 62
>gi|221218981 N-acylsphingosine amidohydrolase 2 isoform a [Homo
sapiens]
Length = 780
Score = 32.3 bits (72), Expect = 4.3
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 1 MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISD-------STSTPATTRV 53
MA++ FS LE LI L V+++ I +AL+ +L + ++ D +T +P T+
Sbjct: 1 MAKRTFSNLETFLIFLLVMMSAITVALLSLLFITSGTIENHKDLGGHFFSTTQSPPATQG 60
Query: 54 TT 55
+T
Sbjct: 61 ST 62
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,886,022
Number of Sequences: 37866
Number of extensions: 3347913
Number of successful extensions: 6353
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 6155
Number of HSP's gapped (non-prelim): 37
length of query: 1827
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1710
effective length of database: 13,817,196
effective search space: 23627405160
effective search space used: 23627405160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.