Search of human proteins with 156523253

Search of human proteins with 156523253

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156523253 RWD domain containing 2A [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156523253 RWD domain containing 2A [Homo sapiens]                  601   e-172
gi|8393018 RWD domain containing 2B [Homo sapiens]                    181   5e-46
gi|226246540 zinc finger, MYND-type containing 12 isoform 2 [Hom...    30   3.3  
gi|226246519 zinc finger, MYND-type containing 12 isoform 1 [Hom...    30   3.3  
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]                     29   4.3  
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]                     29   4.3  
gi|148839305 structural maintenance of chromosomes flexible hing...    29   4.3  
gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens]         28   7.3  
gi|116686106 diptheria toxin resistance protein required for dip...    28   7.3  
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         28   7.3  
gi|38176158 cyclin K isoform 2 [Homo sapiens]                          28   7.3  
gi|4557389 complement component 8, alpha polypeptide precursor [...    28   9.5  
gi|207452735 epiplakin 1 [Homo sapiens]                                28   9.5  
gi|65287717 eukaryotic translation initiation factor 2 alpha kin...    28   9.5  

>gi|156523253 RWD domain containing 2A [Homo sapiens]
          Length = 292

 Score =  601 bits (1550), Expect = e-172
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MSASVKESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVIT 60
           MSASVKESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVIT
Sbjct: 1   MSASVKESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVIT 60

Query: 61  LQIEEPKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCV 120
           LQIEEPKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCV
Sbjct: 61  LQIEEPKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCV 120

Query: 121 CAAIQWLQDNSASYFLNRKLVYEPSTQAKPVKNTFLRMWIYSHHIYQQDLRKKILDVGKR 180
           CAAIQWLQDNSASYFLNRKLVYEPSTQAKPVKNTFLRMWIYSHHIYQQDLRKKILDVGKR
Sbjct: 121 CAAIQWLQDNSASYFLNRKLVYEPSTQAKPVKNTFLRMWIYSHHIYQQDLRKKILDVGKR 180

Query: 181 LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAESVETEGNGEDLRLFH 240
           LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAESVETEGNGEDLRLFH
Sbjct: 181 LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAESVETEGNGEDLRLFH 240

Query: 241 SFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESKSSDS 292
           SFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESKSSDS
Sbjct: 241 SFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESKSSDS 292


>gi|8393018 RWD domain containing 2B [Homo sapiens]
          Length = 319

 Score =  181 bits (460), Expect = 5e-46
 Identities = 103/291 (35%), Positives = 159/291 (54%), Gaps = 14/291 (4%)

Query: 7   ESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEG-TREALPPKIEFVITLQIE- 64
           E  + QL E+++L SMFP + E+ + D  A+  +K  +E  T E    K+ F I + ++ 
Sbjct: 34  EQAEAQLAELDLLASMFPGENELIVNDQLAVAELKDCIEKKTMEGRSSKVYFTINMNLDV 93

Query: 65  --EPKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCVCA 122
             E      L   +P  YP V  ++  RS  L R QQ  LN  LT+++     G++C+  
Sbjct: 94  SDEKMAMFSLACILPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILN 153

Query: 123 AIQWLQDNSASYFLNRKLVYEPSTQA--KPVKNTFLRMWIYSHHIYQQDLRKKILDVGKR 180
           A +W++++++ Y ++R     P+T +  + V   F R+WIYSHHIY +  RK IL+  K 
Sbjct: 154 ATEWVREHASGY-VSRDTSSSPTTGSTVQSVDLIFTRLWIYSHHIYNKCKRKNILEWAKE 212

Query: 181 LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAESVETEGNGEDL---R 237
           L ++GF M GKPG++CVEG +  CEEFW  +R  NWK I  +H E +  +G  ++    R
Sbjct: 213 LSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDGTNDETERQR 272

Query: 238 LFHSFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESK 288
            F  FEE +   +G  G     HM+ GQ  +FL       VFQ+ FG+E +
Sbjct: 273 KFSIFEEKVFSVNGARG----NHMDFGQLYQFLNTKGCGDVFQMFFGVEGQ 319


>gi|226246540 zinc finger, MYND-type containing 12 isoform 2 [Homo
           sapiens]
          Length = 255

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 10  QLQLLEMEMLFSMFPNQGEV----KLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEE 65
           Q  + +M++L  +F N   +    + E +  LT+I    E T +  P K  FV  L+I  
Sbjct: 147 QAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFV--LKILV 204

Query: 66  PKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFD 114
               + +  +    Y   AL L  +  +LD H+Q  + + L S I T D
Sbjct: 205 MFYYLMMNSSKAQEYGMRALSL-AKEQQLDVHEQSTIQE-LLSLISTED 251


>gi|226246519 zinc finger, MYND-type containing 12 isoform 1 [Homo
           sapiens]
          Length = 365

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 10  QLQLLEMEMLFSMFPNQGEV----KLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEE 65
           Q  + +M++L  +F N   +    + E +  LT+I    E T +  P K  FV  L+I  
Sbjct: 257 QAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFV--LKILV 314

Query: 66  PKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFD 114
               + +  +    Y   AL L  +  +LD H+Q  + + L S I T D
Sbjct: 315 MFYYLMMNSSKAQEYGMRALSL-AKEQQLDVHEQSTIQE-LLSLISTED 361


>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
          Length = 981

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 23  FPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEEPKVKI 70
           FP  G  +L+     + IK + E T  ++PP   +V+ LQ EEPK+ +
Sbjct: 613 FPTPGIRRLK---ITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISL 657


>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
          Length = 971

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 23  FPNQGEVKLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEEPKVKI 70
           FP  G  +L+     + IK + E T  ++PP   +V+ LQ EEPK+ +
Sbjct: 603 FPTPGIRRLK---ITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISL 647


>gi|148839305 structural maintenance of chromosomes flexible hinge
           domain containing 1 [Homo sapiens]
          Length = 2005

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 13/94 (13%)

Query: 158 MWIYSHHIYQQDLRKKILDVGKRLDVTGF--CMTGKPGIICVEGFKEHCEEFWHTIRYPN 215
           ++++     + +L  + L VG+R D  GF  C+    GI   E F          I   +
Sbjct: 28  VYLFDRREKESELGDRPLQVGERSDYAGFRACVCQTLGISPEEKF---------VITTTS 78

Query: 216 WKHISCKHAESVETEGNGEDLRLFHSFEELLLEA 249
            K I+C + +  ET  +G  L L  S  +LLL A
Sbjct: 79  RKEITCDNFD--ETVKDGVTLYLLQSVNQLLLTA 110


>gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens]
          Length = 2286

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 14/98 (14%)

Query: 131  SASYFLNRKLVYEPST---------QAKP-VKNTFLRMWIYSHHIYQQDLRKKILDVGKR 180
            S  Y ++RK    P T         QA+P V+  FLR W+ S  +   D+R  ILD    
Sbjct: 1075 SCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIR-AILDWDYY 1133

Query: 181  LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKH 218
            ++  G  +     II +    +  +     +++P+W H
Sbjct: 1134 IERLGSAI---QKIITIPAALQQVKNPVPRVKHPDWLH 1168


>gi|116686106 diptheria toxin resistance protein required for
           diphthamide biosynthesis-like 1 [Homo sapiens]
          Length = 443

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 16/66 (24%), Positives = 36/66 (54%), Gaps = 1/66 (1%)

Query: 28  EVKLEDVNALTNIK-RYLEGTREALPPKIEFVITLQIEEPKVKIDLQVTMPHSYPYVALQ 86
           +++++  + L +++  +   T  AL   I+FV TLQ    ++K + +V++P   P    +
Sbjct: 156 DIRIDTTHLLDSLRLTFPPATALALVSTIQFVSTLQAAAQELKAEYRVSVPQCKPLSPGE 215

Query: 87  LFGRSS 92
           + G +S
Sbjct: 216 ILGCTS 221


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 10/75 (13%)

Query: 53  PKIEFVITLQIEEPKVKIDLQVTMPHSYPY-VALQLFGRSSELDRHQQLLLNKGLTSYIG 111
           PK E ++  +I    +K DLQV  P+ +    A QL G  +++ +         L     
Sbjct: 136 PKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK---------LVQMAW 186

Query: 112 TFDPGELCVCAAIQW 126
           TF    LC   ++QW
Sbjct: 187 TFVNDSLCTTLSLQW 201


>gi|38176158 cyclin K isoform 2 [Homo sapiens]
          Length = 354

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 10/75 (13%)

Query: 53  PKIEFVITLQIEEPKVKIDLQVTMPHSYPY-VALQLFGRSSELDRHQQLLLNKGLTSYIG 111
           PK E ++  +I    +K DLQV  P+ +    A QL G  +++ +         L     
Sbjct: 136 PKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK---------LVQMAW 186

Query: 112 TFDPGELCVCAAIQW 126
           TF    LC   ++QW
Sbjct: 187 TFVNDSLCTTLSLQW 201


>gi|4557389 complement component 8, alpha polypeptide precursor
           [Homo sapiens]
          Length = 584

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 210 TIRYPNWKHISCKHAESVETEGNGEDLRLF---HSFEELLLEAHGDYGLRNDYHMNLGQF 266
           T+    W+ +  ++  + E    G+D + F   ++F +   EA  D G+ ++++ N    
Sbjct: 179 TVYNGEWREL--RYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDL 236

Query: 267 LEFLKKHKSEHVFQILFGI 285
           L  +KK KS+  F +  GI
Sbjct: 237 LSKVKKDKSDS-FGVTIGI 254


>gi|207452735 epiplakin 1 [Homo sapiens]
          Length = 5090

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 14/46 (30%), Positives = 27/46 (58%), Gaps = 2/46 (4%)

Query: 2   SASVKESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEGT 47
           + S  E L++ +L+ + +  +   +G +   DV+A   ++RYLEGT
Sbjct: 241 AVSAAELLEVGILDEQAVQGL--REGRLAAVDVSARAEVRRYLEGT 284


>gi|65287717 eukaryotic translation initiation factor 2 alpha
          kinase 4 [Homo sapiens]
          Length = 1649

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 3/39 (7%)

Query: 52 PPKIEFVIT---LQIEEPKVKIDLQVTMPHSYPYVALQL 87
          PP+I  V+    L  EE  VK+DL+V  P +YP V  ++
Sbjct: 52 PPEINLVLYPQGLTGEEVYVKVDLRVKCPPTYPDVVPEI 90


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,971,520
Number of Sequences: 37866
Number of extensions: 489850
Number of successful extensions: 1093
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1083
Number of HSP's gapped (non-prelim): 23
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.