Search of human proteins with 15619006

Search of human proteins with 15619006

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15619006 vasoactive intestinal peptide receptor 1 [Homo
sapiens]
         (457 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   947   0.0  
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   432   e-121
gi|114205383 secretin receptor precursor [Homo sapiens]               421   e-118
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   392   e-109
gi|58530851 growth hormone releasing hormone receptor isoform a ...   353   1e-97
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    305   7e-83
gi|4503947 glucagon receptor [Homo sapiens]                           286   4e-77
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          284   1e-76
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    282   4e-76
gi|58530853 growth hormone releasing hormone receptor isoform b ...   265   5e-71
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     265   6e-71
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   265   8e-71
gi|4502547 calcitonin receptor [Homo sapiens]                         210   2e-54
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   202   5e-52
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   197   1e-50
gi|5031621 calcitonin receptor-like [Homo sapiens]                    195   6e-50
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   187   1e-47
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   183   3e-46
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   171   1e-42
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             101   1e-21
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]            94   2e-19
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]            94   2e-19
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]            94   2e-19
gi|40807489 egf-like module containing, mucin-like, hormone rece...    93   6e-19
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    91   2e-18
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           81   2e-15
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           81   2e-15
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    79   1e-14
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...    77   2e-14
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      74   3e-13

>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  947 bits (2447), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET 60
           MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
Sbjct: 1   MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET 60

Query: 61  IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI 120
           IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
Sbjct: 61  IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI 120

Query: 121 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH 180
           ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
Sbjct: 121 ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH 180

Query: 181 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL 240
           LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
Sbjct: 181 LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL 240

Query: 241 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP 300
           YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
Sbjct: 241 YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP 300

Query: 301 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF 360
           ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
Sbjct: 301 ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF 360

Query: 361 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH 420
           PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
Sbjct: 361 PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH 420

Query: 421 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV 457
           PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
Sbjct: 421 PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV 457


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  432 bits (1110), Expect = e-121
 Identities = 224/464 (48%), Positives = 303/464 (65%), Gaps = 44/464 (9%)

Query: 15  LAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIG-------CSKMW 67
           LA  L   + PA      +  +C    + + +   CLE+ Q  NE +G       C  MW
Sbjct: 9   LAALLLLPMAPA------MHSDC----IFKKEQAMCLEKIQRANELMGFNDSSPGCPGMW 58

Query: 68  DNLTCWPATPRGQVVVLACPLIFKLFSSIQ-------GRN---------------VSRSC 105
           DN+TCW     G++V+++CP +F++F+  Q       G +               VSR+C
Sbjct: 59  DNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNC 118

Query: 106 TDEGWTHLEPGP-YPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAIL 164
           T++GW+  EP P Y  ACG D+  +   +Q   +Y SVK  YT+GY  SL TL  A  IL
Sbjct: 119 TEDGWS--EPFPHYFDACGFDEYESETGDQD-YYYLSVKALYTVGYSTSLVTLTTAMVIL 175

Query: 165 SLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQY 224
             FRKLHCTRN+IHM+LF+SF+LRA +VFIKD  L+   +S+ C   +V CKA MVFF Y
Sbjct: 176 CRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHY 235

Query: 225 CVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYG 284
           CV++N+FWL +EGLYL+TLL  +FF ER+YF+ Y +IGWG P+    VW   R++F+D G
Sbjct: 236 CVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTG 295

Query: 285 CWDTINS-SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARST 343
           CWD  +S +LWW+IKGP++ SI+VNF+LFI II IL+QKL+ PD+  ++SS Y RLARST
Sbjct: 296 CWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARST 355

Query: 344 LLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKW 403
           LLLIPLFG+HY +FAF P+N     ++VFEL +GSFQGFVVA+LYCFLNGEVQAE++RKW
Sbjct: 356 LLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKW 415

Query: 404 RRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRS 447
           R W +      + K+RHPS  S+G    TQ+S+L++ S   R S
Sbjct: 416 RSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMS 459


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  421 bits (1083), Expect = e-118
 Identities = 213/418 (50%), Positives = 284/418 (67%), Gaps = 18/418 (4%)

Query: 1   MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ----- 55
           MRP    P + L +L   LA A    G     L   CD +Q++  +  QCL+E       
Sbjct: 1   MRPHLSPPLQQL-LLPVLLACAAHSTGA----LPRLCDVLQVLWEEQDQCLQELSREQTG 55

Query: 56  ---LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTH 112
               E    GC  MWDN++CWP++  G++V + CP   ++ +S  G ++ R+CT +GW+ 
Sbjct: 56  DLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNG-SLFRNCTQDGWSE 114

Query: 113 LEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHC 172
             P P  +ACG++   +S +E++  +   +K  YT+GY  SL  LLVA  IL  FR+LHC
Sbjct: 115 TFPRPN-LACGVNVNDSS-NEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHC 172

Query: 173 TRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFW 232
           TRNYIHMHLF+SFILRA + FIKD  LF S +   C     GCK  MV FQYC+MAN+ W
Sbjct: 173 TRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSW 232

Query: 233 LLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-TINS 291
           LLVEGLYL+TLLA+SFFSERKY  G++  GWG P+ F  +W IAR   ED GCWD   N+
Sbjct: 233 LLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANA 292

Query: 292 SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFG 351
           S+WWII+GP++ SIL+NFILFI I+RIL++KLR  + R ++ S Y RLARSTLLLIPLFG
Sbjct: 293 SIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFG 352

Query: 352 VHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQ 409
           +HYI+FAF P++   E+++ FEL +GSFQG VVA+LYCFLNGEVQ E+++KW++WHL+
Sbjct: 353 IHYIVFAFSPED-AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  392 bits (1008), Expect = e-109
 Identities = 210/447 (46%), Positives = 278/447 (62%), Gaps = 31/447 (6%)

Query: 21  WALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETI-GCSKMWDNLTCWPATPRG 79
           W L P       +  EC +   I+ +  +C E  + + E    CS +WDN+TCW     G
Sbjct: 13  WLLAPVNS----IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVG 68

Query: 80  QVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFY 139
           + V + CP +F  F S  G N+S++CT +GW+   P  +  ACG  D     DE +  FY
Sbjct: 69  ETVTVPCPKVFSNFYSKAG-NISKNCTSDGWSETFPD-FVDACGYSDPE---DESKITFY 123

Query: 140 GSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLAL 199
             VK  YT+GY +SL +L   + IL LFRKLHCTRNYIH++LF+SFILRA +V +KD  L
Sbjct: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL 183

Query: 200 FDSGESDQCSEGS---VGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFW 256
           + S  +  C +     VGCK ++VF QYC+MANFFWLLVEGLYL+TLL V+    R+ F 
Sbjct: 184 YSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFL 242

Query: 257 GYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSL-WWIIKGPILTSILVNFILFICI 315
            Y+LIGWG+P+     WT AR++ ED GCWDT + S+ WW+I+ PIL SI+VNF+LFI I
Sbjct: 243 AYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISI 302

Query: 316 IRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELV 375
           IRILLQKL  PD+  +D S Y RLA+STLLLIPLFGVHY++FA FP +   + +++FEL 
Sbjct: 303 IRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELC 362

Query: 376 VGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVS 435
           +GSFQG VVA+LYCFLN EVQ EL+RKWR            +   PS   +   C +  S
Sbjct: 363 LGSFQGLVVAVLYCFLNSEVQCELKRKWR-----------SRCPTPSASRDYRVCGSSFS 411

Query: 436 M-----LTRVSPGARRSSSFQAEVSLV 457
                   +   G+R  S  Q E S++
Sbjct: 412 RNGSEGALQFHRGSRAQSFLQTETSVI 438


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  353 bits (907), Expect = 1e-97
 Identities = 181/414 (43%), Positives = 246/414 (59%), Gaps = 7/414 (1%)

Query: 23  LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-LENETIGCSKMWDNLTCWPATPRGQV 81
           L P       +  ECD++  +      CL+ A+ + N T+GC   WD L CWP    G+ 
Sbjct: 14  LSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEW 73

Query: 82  VVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGS 141
           V L CP  F  FSS  G  V R CT  GW+   P PYP+AC +  +  + +E    ++ +
Sbjct: 74  VTLPCPDFFSHFSSESGA-VKRDCTITGWSEPFP-PYPVACPVPLELLAEEES---YFST 128

Query: 142 VKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFD 201
           VK  YT+G+ +S+  L VA  IL   R+LHC RNY+H  LF +FIL+A AVF+KD ALF 
Sbjct: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188

Query: 202 SGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILI 261
           S ++D CS  +V CK ++    +  M NF WLL E +YL  LLA +  S R+ FW  +L 
Sbjct: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLA 248

Query: 262 GWGVPSTFTMVWTIARIHFEDYGCWDTINSS-LWWIIKGPILTSILVNFILFICIIRILL 320
           GWG+P  FT  W   ++ FED  CWD  ++S  WWIIKGPI+ S+ VNF LF+ IIRIL+
Sbjct: 249 GWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILV 308

Query: 321 QKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQ 380
           +KL P        S Y RL++STL LIPLFG+HYI+F F PDN    +++  EL +GSFQ
Sbjct: 309 RKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQ 368

Query: 381 GFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQV 434
           GF+VAILYCFLN EV+ E+ RKW     + +  W  + +  +   + A   T +
Sbjct: 369 GFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSM 422


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  305 bits (780), Expect = 7e-83
 Identities = 164/411 (39%), Positives = 235/411 (57%), Gaps = 35/411 (8%)

Query: 63  CSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIAC 122
           C   WD++ CWP    G+VV + CP     F+     +  R C   G   L PG      
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFN--HKGHAYRRCDRNGSWELVPGHNRTWA 165

Query: 123 GLDD--KAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH 180
              +  K  + + ++   +  +   YT+GY +SLA+L VA  IL+ FR+LHCTRNYIHMH
Sbjct: 166 NYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMH 225

Query: 181 LFISFILRAAAVFIKDLALFDSGESDQCSE---------------------GSVGCKAAM 219
           LF+SF+LRA ++F+KD  L+     D+                        G  GC+ A+
Sbjct: 226 LFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAV 285

Query: 220 VFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIH 279
            FF Y +  N++W+LVEGLYL++L+ ++FFSE+KY WG+ + GWG+P+ F  VW   R  
Sbjct: 286 TFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRAT 345

Query: 280 FEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDS-SPYSR 338
             + GCWD  + +  WII+ PIL SI++NFILFI I+R+L  KLR  +  + D+   Y +
Sbjct: 346 LANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405

Query: 339 LARSTLLLIPLFGVHYIMFAFFP----DNFKPEVKMVFELVVGSFQGFVVAILYCFLNGE 394
           L +STL+L+PLFGVHYI+F   P         +V+M +E++  SFQGF VAI+YCF NGE
Sbjct: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465

Query: 395 VQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGAR 445
           VQAE+++ W RW L   L +  K R    GS+  +    VS  +  + G R
Sbjct: 466 VQAEIKKSWSRWTL--ALDFKRKAR---SGSSSYSYGPMVSHTSVTNVGPR 511


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  286 bits (731), Expect = 4e-77
 Identities = 154/369 (41%), Positives = 216/369 (58%), Gaps = 21/369 (5%)

Query: 63  CSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG-WTHLEPG-PYPI 120
           C++ +D  +CWP TP      ++CP        +Q R V + C  +G W     G P+  
Sbjct: 58  CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRD 117

Query: 121 A--CGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIH 178
           A  C +D +   + ++    Y S +  YT+GY LSL  LL+A AIL    KLHCTRN IH
Sbjct: 118 ASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIH 177

Query: 179 MHLFISFILRAAAVFIKDLALF---------DSGESDQCSEGSV-GCKAAMVFFQYCVMA 228
            +LF SF+L+A++V + D  L          D   S   S+G+V GC+ A VF QY ++A
Sbjct: 178 ANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVA 237

Query: 229 NFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCW-D 287
           N+ WLLVEGLYL+ LL ++   ER +F  Y+ IGWG P  F + W + +  FE+  CW  
Sbjct: 238 NYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTS 297

Query: 288 TINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLI 347
             N   WWI++ P+  +IL+NF +F+ I+++L+ KLR   +  +D     RLA+STL LI
Sbjct: 298 NDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYK--FRLAKSTLTLI 355

Query: 348 PLFGVHYIMFAFFPDNFKP----EVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKW 403
           PL GVH ++FAF  D          K+ F+L + SFQG +VA+LYCFLN EVQ+ELRR+W
Sbjct: 356 PLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRW 415

Query: 404 RRWHLQGVL 412
            RW L  VL
Sbjct: 416 HRWRLGKVL 424


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  284 bits (726), Expect = 1e-76
 Identities = 180/459 (39%), Positives = 245/459 (53%), Gaps = 30/459 (6%)

Query: 5   SPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCS 64
           +P P R   +L G +  A     G    L E     +    Q ++ L E       + C+
Sbjct: 4   APGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCN 63

Query: 65  KMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG-WTHLEPGPYP---- 119
           + +D   CWP    G  V ++CP      SS+   +V R CT EG W   +    P    
Sbjct: 64  RTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDL 123

Query: 120 IACGLDDKAA-SLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIH 178
             C    +   S  E+Q +F   +   YT+GY LS + L++A+AIL  FR LHCTRNYIH
Sbjct: 124 SECEESKRGERSSPEEQLLFLYII---YTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180

Query: 179 MHLFISFILRAAAVFIKDLAL---FDSGESDQCSEG------SVGCKAAMVFFQYCVMAN 229
           ++LF SFILRA +VFIKD AL   + +       +G      S+ C+   +  QYCV AN
Sbjct: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN 240

Query: 230 FFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-T 288
           ++WLLVEG+YLYTLLA S  SE+  F  Y+ IGWGVP  F + W I +  +ED GCW   
Sbjct: 241 YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN 300

Query: 289 INSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIP 348
            N + W II+ PIL +I VNF++F+ +I I++ KL+   + K+D     RLA+STL LIP
Sbjct: 301 SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLTLIP 358

Query: 349 LFGVHYIMFAFFPDNFKPE----VKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWR 404
           L G H ++FAF  D         +K+  EL   SFQG +VAILYCF+N EVQ E R+ W 
Sbjct: 359 LLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWE 418

Query: 405 RW-----HLQGVLGWNPKYRHPSGGSNGATCSTQVSMLT 438
           RW     H+Q      P     S  S+GAT  + +   T
Sbjct: 419 RWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTAT 457


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  282 bits (722), Expect = 4e-76
 Identities = 164/434 (37%), Positives = 235/434 (54%), Gaps = 45/434 (10%)

Query: 54  AQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVS-RSCTDEG-WT 111
           AQL+     C   WD L CWP    G++  + CP     F+    + V+ R C   G W 
Sbjct: 54  AQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNH---KGVAFRHCNPNGTWD 110

Query: 112 HLEP-----GPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSL 166
            +         Y           S+ +Q+  F+  +   YT+GY +S  +L VA  I+  
Sbjct: 111 FMHSLNKTWANYSDCLRFLQPDISIGKQE--FFERLYVMYTVGYSISFGSLAVAILIIGY 168

Query: 167 FRKLHCTRNYIHMHLFISFILRAAAVFIKDLALF------------------DSGESDQC 208
           FR+LHCTRNYIHMHLF+SF+LRA ++F+KD  +                   +S E+   
Sbjct: 169 FRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSV 228

Query: 209 SEGS-VGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
            +   +GCK A+V F Y +  N++W+LVEGLYL+ L+ V+FFS+ KY WG+ILIGWG P+
Sbjct: 229 DKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPA 288

Query: 268 TFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPD 327
            F   W +AR    D  CW+     + WI + PIL +I +NFILF+  +R+L  K+   +
Sbjct: 289 AFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348

Query: 328 IRKSDS-SPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKP---EVKMVFELVVGSFQGFV 383
               D+   Y +LA+STL+L+ +FGVHYI+F   P +F     E++M  EL   SFQGF 
Sbjct: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408

Query: 384 VAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPG 443
           V+I+YC+ NGEVQAE+++ W RW+L   + W    R P  GS    C    S+LT V+  
Sbjct: 409 VSIIYCYCNGEVQAEVKKMWSRWNLS--VDWK---RTPPCGSR--RCG---SVLTTVTHS 458

Query: 444 ARRSSSFQAEVSLV 457
               S   A   +V
Sbjct: 459 TSSQSQVAASTRMV 472


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  265 bits (678), Expect = 5e-71
 Identities = 134/305 (43%), Positives = 181/305 (59%), Gaps = 7/305 (2%)

Query: 23  LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-LENETIGCSKMWDNLTCWPATPRGQV 81
           L P       +  ECD++  +      CL+ A+ + N T+GC   WD L CWP    G+ 
Sbjct: 14  LSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEW 73

Query: 82  VVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGS 141
           V L CP  F  FSS  G  V R CT  GW+   P PYP+AC +  +  + +E    ++ +
Sbjct: 74  VTLPCPDFFSHFSSESGA-VKRDCTITGWSEPFP-PYPVACPVPLELLAEEES---YFST 128

Query: 142 VKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFD 201
           VK  YT+G+ +S+  L VA  IL   R+LHC RNY+H  LF +FIL+A AVF+KD ALF 
Sbjct: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188

Query: 202 SGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILI 261
           S ++D CS  +V CK ++    +  M NF WLL E +YL  LLA +  S R+ FW  +L 
Sbjct: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLA 248

Query: 262 GWGVPSTFTMVWTIARIHFEDYGCWDTINSS-LWWIIKGPILTSILVNFILFICIIRILL 320
           GWG+P  FT  W   ++ FED  CWD  ++S  WWIIKGPI+ S+ VNF LF+ IIRIL+
Sbjct: 249 GWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILV 308

Query: 321 QKLRP 325
           +KL P
Sbjct: 309 RKLEP 313


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  265 bits (677), Expect = 6e-71
 Identities = 160/414 (38%), Positives = 224/414 (54%), Gaps = 30/414 (7%)

Query: 61  IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG----WTHLEPG 116
           + C+  +D   CW           +CP        +    V R C  +G    W      
Sbjct: 59  LACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQC 118

Query: 117 PYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNY 176
             P     +   A LD  Q +    ++  YT+GY LSLATLL+A  ILSLFR+LHCTRNY
Sbjct: 119 ENP-----EKNEAFLD--QRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNY 171

Query: 177 IHMHLFISFILRAAAVFIKDLALFDSGE--SDQC----SEGSVGCKAAMVFFQYCVMANF 230
           IH++LF SF+LRAAA+  +D  L   G    DQ     ++    C+ A +  QYCV AN+
Sbjct: 172 IHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANY 231

Query: 231 FWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTIN 290
            WLLVEG+YL++LL +   SE  +F  Y+L+GWG P+ F + W I R  +E+  CW+   
Sbjct: 232 TWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNE 291

Query: 291 -SSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPL 349
             ++WWII+ PIL +IL+NF++FI I+ ILL KLR   +R  D     RLARSTL L+PL
Sbjct: 292 VKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR--LRLARSTLTLVPL 349

Query: 350 FGVHYIMFAFFPDNFKPE----VKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRR 405
            GVH ++FA   +          K+ FE+ + SFQGF+V++LYCF+N EVQ+E+RR W  
Sbjct: 350 LGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH 409

Query: 406 WHLQGVLGWNPK------YRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAE 453
             L+  LG   +      +R    GS      T   + +   PG    +S + E
Sbjct: 410 CRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELE 463


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  265 bits (676), Expect = 8e-71
 Identities = 155/385 (40%), Positives = 214/385 (55%), Gaps = 28/385 (7%)

Query: 46  QHKQ-CLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRS 104
           Q+KQ CL +   E   I C+  +D   CWP +  G V V  CP     +S        R 
Sbjct: 78  QYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSV-PCPSYLPWWSEESSGRAYRH 136

Query: 105 CTDEG-WTHLEPGPYPIACGLDDKAASLD---EQQTMFYGSVKT---GYTIGYGLSLATL 157
           C  +G W  +E          DD   S +   +Q    Y  + T    YT+GY  SL +L
Sbjct: 137 CLAQGTWQTIENAT---DIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISL 193

Query: 158 LVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDS---------GESDQC 208
            +A  +L   RKLHCTRNYIHM+LF SFILR  AV +KD+  ++S         G     
Sbjct: 194 FLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYL 253

Query: 209 SEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPST 268
           SE S  C++  V   Y V AN+ WLLVEGLYL+TLL  +   ER+ +  Y+L+GW  P  
Sbjct: 254 SEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVL 313

Query: 269 FTMVWTIARIHFEDYGCWDTI-NSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPD 327
           F + W  AR H E+ GCW T  N  +WWII+GP++  + VNF +F+ I+++L+ KL+   
Sbjct: 314 FVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQ 373

Query: 328 IRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDN----FKPEVKMVFELVVGSFQGFV 383
           +   D     RLA+STL+LIPL GVH I+F+F  D+    F   +++  +L + SF GF+
Sbjct: 374 MCFRDYK--YRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFL 431

Query: 384 VAILYCFLNGEVQAELRRKWRRWHL 408
           VA+ Y F NGEV+AELR+ W R+ L
Sbjct: 432 VALQYGFANGEVKAELRKYWVRFLL 456


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  210 bits (534), Expect = 2e-54
 Identities = 121/405 (29%), Positives = 217/405 (53%), Gaps = 34/405 (8%)

Query: 41  QMIEVQHKQCLEEAQ----LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSI 96
           +M++ Q+K C +  Q     + E   C++ WD   CW  TP G +    CP  F  F   
Sbjct: 47  KMMDAQYK-CYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPS 105

Query: 97  QGRNVSRSCTDEGWTHLEP------GPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGY 150
           +   V++ C ++G     P        Y +      +   L     ++Y ++     +G+
Sbjct: 106 E--KVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPE--KLKNAYVLYYLAI-----VGH 156

Query: 151 GLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSE 210
            LS+ TL+++  I   FR L C R  +H ++F+++IL +  + I  + +  +GE  +   
Sbjct: 157 SLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVR--R 214

Query: 211 GSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFT 270
             V CK    F QY +  N+FW+L EG+YL+TL+ V+ F+E++    Y L+GWG P   T
Sbjct: 215 DPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPT 274

Query: 271 MVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRK 330
            +  I R  + +  CW ++ + L +II GP++ +++VNF   + I+R+L+ K+R  +  +
Sbjct: 275 TIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR--ETHE 332

Query: 331 SDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGS---FQGFVVAIL 387
           ++S  Y +  ++T++L+PL G+ +++F + P N    +  +++ V+ S   FQGF VA +
Sbjct: 333 AESHMYLKAVKATMILVPLLGIQFVVFPWRPSN--KMLGKIYDYVMHSLIHFQGFFVATI 390

Query: 388 YCFLNGEVQAELRRKWRRWHLQGVLGWNPKY-RHPSGGSNGATCS 431
           YCF N EVQ  ++R+W ++ +Q    WN ++ R PS  S  A  +
Sbjct: 391 YCFCNNEVQTTVKRQWAQFKIQ----WNQRWGRRPSNRSARAAAA 431


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  202 bits (514), Expect = 5e-52
 Identities = 114/344 (33%), Positives = 184/344 (53%), Gaps = 23/344 (6%)

Query: 71  TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130
           TCWP +P GQ+VV  CP  F         N  R C       L  G +       +    
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105

Query: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFIL 187
           L+E++     ++ +V   Y +G+ +SL  LLVA  +    R + C RN IH +L  +FIL
Sbjct: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164

Query: 188 RAAAVFIKDLALFDSGESDQCSEGSVG-CKAAMVFFQYCVMANFFWLLVEGLYLYTLLAV 246
           R A  F+  L +     S +  + +VG C+     + Y  + NFFW+  EG YL+T + +
Sbjct: 165 RNATWFVVQLTM-----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 219

Query: 247 SFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLW--WIIKGPILTS 304
           ++ ++R   W +I IGWGVP    + W I ++++++  CW      ++  +I +GP++  
Sbjct: 220 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 279

Query: 305 ILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFP--D 362
           +L+NFI    I+RIL+ KLR      S++  Y +  ++TL+L+PL G+ Y++F   P  D
Sbjct: 280 LLINFIFLFNIVRILMTKLRAS--TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGED 337

Query: 363 NFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRW 406
                V + F   + SFQGF V++ YCFLN EV++ +R++W RW
Sbjct: 338 EVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  197 bits (502), Expect = 1e-50
 Identities = 112/349 (32%), Positives = 180/349 (51%), Gaps = 16/349 (4%)

Query: 63  CSKMWDNL-TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIA 121
           C+   D + TCWP +  G +V   CP  F        RN  R C + G    +       
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99

Query: 122 CGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHL 181
             LDDK    D    + Y        +G+ +S+A L+ A  +    R + C RN IH +L
Sbjct: 100 PILDDKQRKYD----LHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNL 155

Query: 182 FISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLY 241
             +FILR    F+  L   +  ES++     V C+     F Y V+ NFFW+ VEG YL+
Sbjct: 156 ITTFILRNVMWFLLQLVDHEVHESNE-----VWCRCITTIFNYFVVTNFFWMFVEGCYLH 210

Query: 242 TLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCW--DTINSSLWWIIKG 299
           T + +++ +ER     ++ IGW +P    + W I ++++E+  CW        + +I +G
Sbjct: 211 TAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQG 270

Query: 300 PILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAF 359
           PI+  +L+NF+    I+RIL+ KLR      S++  Y +  ++TL+L+PL G+ Y++F  
Sbjct: 271 PIILVLLINFVFLFNIVRILMTKLRAS--TTSETIQYRKAVKATLVLLPLLGITYMLFFV 328

Query: 360 FP--DNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRW 406
            P  D+    + + F   + SFQGF V++ YCF NGEV++ +R++W RW
Sbjct: 329 NPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRW 377


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  195 bits (496), Expect = 6e-50
 Identities = 108/368 (29%), Positives = 192/368 (52%), Gaps = 16/368 (4%)

Query: 47  HKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCT 106
           +++ +++   + E + C++ WD   CW     G   +  CP  F+ F   +   V++ C 
Sbjct: 49  YQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSE--KVTKICD 106

Query: 107 DEGWTHLEPGPYPIACGLDDKAASLDEQQ----TMFYGSVKTGYTIGYGLSLATLLVATA 162
            +G     P              +  E+      +FY ++     IG+GLS+A+LL++  
Sbjct: 107 QDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTI-----IGHGLSIASLLISLG 161

Query: 163 ILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFF 222
           I   F+ L C R  +H +LF SF+  +    I   A+  +      +   V CK +    
Sbjct: 162 IFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAV--ANNQALVATNPVSCKVSQFIH 219

Query: 223 QYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFED 282
            Y +  N+FW+L EG+YL+TL+ V+ F+E+++   Y  +GWG P     +  IAR  + +
Sbjct: 220 LYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYN 279

Query: 283 YGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARS 342
             CW + ++ L +II GPI  ++LVN    + I+R+L+ KL+     +++S+ Y +  R+
Sbjct: 280 DNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKV--THQAESNLYMKAVRA 337

Query: 343 TLLLIPLFGVHYIMFAFFPD-NFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRR 401
           TL+L+PL G+ +++  + P+     EV      ++  FQG +V+ ++CF NGEVQA LRR
Sbjct: 338 TLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRR 397

Query: 402 KWRRWHLQ 409
            W ++ +Q
Sbjct: 398 NWNQYKIQ 405


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  187 bits (476), Expect = 1e-47
 Identities = 114/373 (30%), Positives = 185/373 (49%), Gaps = 52/373 (13%)

Query: 71  TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130
           TCWP +P GQ+VV  CP  F         N  R C       L  G +       +    
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105

Query: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAIL----------------------- 164
           L+E++     ++ +V   Y +G+ +SL  LLVA  +                        
Sbjct: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAP 164

Query: 165 ------SLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVG-CKA 217
                  + R + C RN IH +L  +FILR A  F+  L +     S +  + +VG C+ 
Sbjct: 165 WSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM-----SPEVHQSNVGWCRL 219

Query: 218 AMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIAR 277
               + Y  + NFFW+  EG YL+T + +++ ++R   W +I IGWGVP    + W I +
Sbjct: 220 VTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGK 279

Query: 278 IHFEDYGCWDTINSSLW--WIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSP 335
           +++++  CW      ++  +I +GP++  +L+NFI    I+RIL+ KLR      S++  
Sbjct: 280 LYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS--TTSETIQ 337

Query: 336 YSRLARSTLLLIPLFGVHYIMFAFFP--DNFKPEVKMVFELVVGSFQGFVVAILYCFLNG 393
           Y +  ++TL+L+PL G+ Y++F   P  D     V + F   + SFQGF V++ YCFLN 
Sbjct: 338 YRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNS 397

Query: 394 EVQAELRRKWRRW 406
           EV++ +R++W RW
Sbjct: 398 EVRSAIRKRWHRW 410


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  183 bits (464), Expect = 3e-46
 Identities = 93/264 (35%), Positives = 153/264 (57%), Gaps = 12/264 (4%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G+ +SL  LLVA  +    R + C RN IH +L  +FILR A  F+  L +     S +
Sbjct: 85  LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM-----SPE 139

Query: 208 CSEGSVG-CKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVP 266
             + +VG C+     + Y  + NFFW+  EG YL+T + +++ ++R   W +I IGWGVP
Sbjct: 140 VHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVP 199

Query: 267 STFTMVWTIARIHFEDYGCWDTINSSLW--WIIKGPILTSILVNFILFICIIRILLQKLR 324
               + W I ++++++  CW      ++  +I +GP++  +L+NFI    I+RIL+ KLR
Sbjct: 200 FPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR 259

Query: 325 PPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFP--DNFKPEVKMVFELVVGSFQGF 382
                 S++  Y +  ++TL+L+PL G+ Y++F   P  D     V + F   + SFQGF
Sbjct: 260 AS--TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGF 317

Query: 383 VVAILYCFLNGEVQAELRRKWRRW 406
            V++ YCFLN EV++ +R++W RW
Sbjct: 318 FVSVFYCFLNSEVRSAIRKRWHRW 341


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  171 bits (433), Expect = 1e-42
 Identities = 106/342 (30%), Positives = 176/342 (51%), Gaps = 33/342 (9%)

Query: 71  TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130
           TCWP +P GQ+VV  CP  F         N  R C       L  G +       +    
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105

Query: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFIL 187
           L+E++     ++ +V   Y +G+ +SL  LLVA  +    R + C RN IH +L  +FIL
Sbjct: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164

Query: 188 RAAAVFIKDLALFDSGESDQCSEGSVG-CKAAMVFFQYCVMANFFWLLVEGLYLYTLLAV 246
           R A  F+  L +     S +  + +VG C+     + Y  + NFFW+  EG YL+T + +
Sbjct: 165 RNATWFVVQLTM-----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 219

Query: 247 SFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLW--WIIKGPILTS 304
           ++ ++R   W +I IGWGVP    + W I ++++++  CW      ++  +I +GP++  
Sbjct: 220 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 279

Query: 305 ILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNF 364
           +L+NFI    I+RIL+ KLR      S++  Y +  ++TL+L+PL G+ Y++  FF +  
Sbjct: 280 LLINFIFLFNIVRILMTKLRAS--TTSETIQYRKAVKATLVLLPLLGITYML--FFVNPG 335

Query: 365 KPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRW 406
           + EV  V  +   SF       L  F   +V++ +R++W RW
Sbjct: 336 EDEVSRVVFIYFNSF-------LESF---QVRSAIRKRWHRW 367


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  101 bits (252), Expect = 1e-21
 Identities = 78/306 (25%), Positives = 130/306 (42%), Gaps = 27/306 (8%)

Query: 152 LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG 211
           L L   LV  A+LS    +   R +IH +L  + ++    + I          S +   G
Sbjct: 579 LCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLI----------SFRLEPG 628

Query: 212 SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE---RKYFWGYILIGWGVPST 268
           +  C+   V   Y  ++ F W+LVEGL+LY+++   F SE    +Y++G   +GWG P  
Sbjct: 629 TTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYG---MGWGFPLL 685

Query: 269 FTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLR 324
             ++        + YG    CW ++ S   W    P L  I+VN  + I + R++ Q   
Sbjct: 686 ICII--SLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISA 743

Query: 325 PPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVV 384
                  D S +   A++  +L+P+ G  ++ F     N    V       + S QG  +
Sbjct: 744 DNYKIHGDPSAFKLTAKAVAVLLPILGTSWV-FGVLAVNGCAVVFQYMFATLNSLQGLFI 802

Query: 385 AILYCFLNGEVQAELRRKWRRWHLQG----VLGWNPKYRHPSGGSNGATCSTQVSMLTRV 440
            + +C LN EV+A  + K + W L           P +     G+     ST++S   + 
Sbjct: 803 FLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNGTRPGMASTKLSPWDKS 862

Query: 441 SPGARR 446
           S  A R
Sbjct: 863 SHSAHR 868


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/262 (27%), Positives = 118/262 (45%), Gaps = 20/262 (7%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G  LSL  LL+      L R +  +R  IH+HL I   + +         +F +G  ++
Sbjct: 504 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST--------IFLAGIENE 555

Query: 208 CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             +  + C+       YC +A F W+ +EGL LY L+   F  +        LIG+GVP 
Sbjct: 556 GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVP- 614

Query: 268 TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
              +V   A I+ + YG    CW        W   GP+   IL N ++F+  +  L QK 
Sbjct: 615 -LLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKF 673

Query: 324 RP--PDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQG 381
               PD++K   +    L  + +  + L G  ++   F  D+    +  VF  ++   QG
Sbjct: 674 SEINPDMKKLKKA--RALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVF-TILNCLQG 730

Query: 382 FVVAILYCFLNGEVQAELRRKW 403
             + +L+C LN +V+ E  RKW
Sbjct: 731 AFLYLLHCLLNKKVREEY-RKW 751


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/262 (27%), Positives = 118/262 (45%), Gaps = 20/262 (7%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G  LSL  LL+      L R +  +R  IH+HL I   + +         +F +G  ++
Sbjct: 460 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST--------IFLAGIENE 511

Query: 208 CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             +  + C+       YC +A F W+ +EGL LY L+   F  +        LIG+GVP 
Sbjct: 512 GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVP- 570

Query: 268 TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
              +V   A I+ + YG    CW        W   GP+   IL N ++F+  +  L QK 
Sbjct: 571 -LLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKF 629

Query: 324 RP--PDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQG 381
               PD++K   +    L  + +  + L G  ++   F  D+    +  VF  ++   QG
Sbjct: 630 SEINPDMKKLKKA--RALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVF-TILNCLQG 686

Query: 382 FVVAILYCFLNGEVQAELRRKW 403
             + +L+C LN +V+ E  RKW
Sbjct: 687 AFLYLLHCLLNKKVREEY-RKW 707


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/262 (27%), Positives = 118/262 (45%), Gaps = 20/262 (7%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G  LSL  LL+      L R +  +R  IH+HL I   + +         +F +G  ++
Sbjct: 553 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST--------IFLAGIENE 604

Query: 208 CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             +  + C+       YC +A F W+ +EGL LY L+   F  +        LIG+GVP 
Sbjct: 605 GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVP- 663

Query: 268 TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
              +V   A I+ + YG    CW        W   GP+   IL N ++F+  +  L QK 
Sbjct: 664 -LLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKF 722

Query: 324 RP--PDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQG 381
               PD++K   +    L  + +  + L G  ++   F  D+    +  VF  ++   QG
Sbjct: 723 SEINPDMKKLKKA--RALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVF-TILNCLQG 779

Query: 382 FVVAILYCFLNGEVQAELRRKW 403
             + +L+C LN +V+ E  RKW
Sbjct: 780 AFLYLLHCLLNKKVREEY-RKW 800


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 22/263 (8%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G  +SL  L++A A   L R +     Y+H+HL +  +L A  +F+  +   D+     
Sbjct: 608 VGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL-AKTLFLAGIHKTDN----- 661

Query: 208 CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLY----TLLAVSFFSERKYFWGYI-LIG 262
                +GC     F  Y  +A FFW+LVE + L+     L  V++FS R     +I   G
Sbjct: 662 ----KMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFG 717

Query: 263 WGVPSTFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRI 318
           +G+P    ++   A +  + YG    CW    +   W   GP+ T I++N +L    + I
Sbjct: 718 YGLPMLVVVI--SASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWI 775

Query: 319 LLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGS 378
           L Q+L   +   S       L       + + G  +++  F        +  +F  ++ S
Sbjct: 776 LRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLF-TIINS 834

Query: 379 FQGFVVAILYCFLNGEVQAELRR 401
            QG  + +++C LNG+V+ E +R
Sbjct: 835 LQGAFIFLIHCLLNGQVREEYKR 857


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 82/292 (28%), Positives = 129/292 (44%), Gaps = 37/292 (12%)

Query: 152  LSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEG 211
            LSLA LLVA  +LSL R L    + IH HL       A A+F+  L +F  G +   +E 
Sbjct: 2478 LSLAALLVAFVLLSLVRMLRSNLHSIHKHL-------AVALFLSQL-VFVIGINQ--TEN 2527

Query: 212  SVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTM 271
               C    +   Y  M+ F W LVE L++Y +L      +      Y ++GWG+P+  T 
Sbjct: 2528 PFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIVTG 2587

Query: 272  VWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPD 327
            +     +  + YG    CW ++  +L W   GPI   I++N +  +   ++  Q+     
Sbjct: 2588 L--AVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLSAKVSCQRKHHYY 2645

Query: 328  IRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAIL 387
             +K   S    L R+  LL+ L    +++     +        +F +  G  QG  V + 
Sbjct: 2646 GKKGIVS----LLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAIFSG-LQGPFVLLF 2700

Query: 388  YCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTR 439
            +C LN EV         R HL+GVLG    +   S        +T+ ++LTR
Sbjct: 2701 HCVLNQEV---------RKHLKGVLGGRKLHLEDS-------ATTRATLLTR 2736


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 76/306 (24%), Positives = 128/306 (41%), Gaps = 33/306 (10%)

Query: 148  IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
            +G  +SL  L +  +     R L   RN IH +L I+  L A  +F+  +          
Sbjct: 866  VGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL-AELLFLVGI---------D 915

Query: 208  CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             ++  + C        Y  +A F WL +EG++LY LL   F SE      Y L G+  P+
Sbjct: 916  KTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 975

Query: 268  TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
               +V   A I +  YG    CW  +++   W   GP+   I+VN +  +  +    + +
Sbjct: 976  --LVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLH---KMI 1030

Query: 324  RPPDIRKSDSSPYSRL---ARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVV-GSF 379
            R   + K DSS    +   A   + L+ L G+ +     F +  K  V M +      +F
Sbjct: 1031 RSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN--KESVVMAYLFTTFNAF 1088

Query: 380  QGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTR 439
            QG  + + +C L  +V  E  +  R  +           R P GG++G+  ++ +   TR
Sbjct: 1089 QGVFIFVFHCALQKKVHKEYSKCLRHSYC--------CIRSPPGGTHGSLKTSAMRSNTR 1140

Query: 440  VSPGAR 445
               G +
Sbjct: 1141 YYTGTQ 1146


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 76/306 (24%), Positives = 128/306 (41%), Gaps = 33/306 (10%)

Query: 148  IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
            +G  +SL  L +  +     R L   RN IH +L I+  L A  +F+  +          
Sbjct: 861  VGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL-AELLFLVGI---------D 910

Query: 208  CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             ++  + C        Y  +A F WL +EG++LY LL   F SE      Y L G+  P+
Sbjct: 911  KTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 970

Query: 268  TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
               +V   A I +  YG    CW  +++   W   GP+   I+VN +  +  +    + +
Sbjct: 971  --LVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLH---KMI 1025

Query: 324  RPPDIRKSDSSPYSRL---ARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVV-GSF 379
            R   + K DSS    +   A   + L+ L G+ +     F +  K  V M +      +F
Sbjct: 1026 RSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN--KESVVMAYLFTTFNAF 1083

Query: 380  QGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTR 439
            QG  + + +C L  +V  E  +  R  +           R P GG++G+  ++ +   TR
Sbjct: 1084 QGVFIFVFHCALQKKVHKEYSKCLRHSYC--------CIRSPPGGTHGSLKTSAMRSNTR 1135

Query: 440  VSPGAR 445
               G +
Sbjct: 1136 YYTGTQ 1141


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 73/268 (27%), Positives = 117/268 (43%), Gaps = 34/268 (12%)

Query: 148  IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLA-LFDSGESD 206
            +G  LSL  LL+       FR L   RN IH +L IS       +F+ +L  L     +D
Sbjct: 883  VGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCIS-------LFVAELLFLIGINRTD 935

Query: 207  QCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSE---RKYFWGYILIGW 263
            Q     + C        +  +A F W+ +EG+ LY +L   F SE   RKYF+   L+G+
Sbjct: 936  Q----PIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFY---LVGY 988

Query: 264  GVPSTFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFI-LFICIIRI 318
            G+P+    V   A + +  YG    CW  +++   W   GP    I++N I L I + ++
Sbjct: 989  GMPALIVAV--SAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKM 1046

Query: 319  LLQK--LRP-----PDIRKSDSSPYSR-LARSTLLLIPLFGVHYIMFAFFPDNFKPEVKM 370
                  L+P      +I   D+ P+ +      + L+ L G+ +  F     N    +  
Sbjct: 1047 FHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTW-AFGLMYINESTVIMA 1105

Query: 371  VFELVVGSFQGFVVAILYCFLNGEVQAE 398
                +  S QG  + I +C L  +V+ E
Sbjct: 1106 YLFTIFNSLQGMFIFIFHCVLQKKVRKE 1133


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 66/267 (24%), Positives = 112/267 (41%), Gaps = 23/267 (8%)

Query: 148 IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
           +G  +SL  LL+A     L + +  T   +H+ L +   L A  +F+  +          
Sbjct: 362 VGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL-AHLLFLVGI---------D 411

Query: 208 CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLY----TLLAVSFFS-ERKYFWGYILIG 262
            +E  V C        Y  +A F W+L+EG++L+     L  V++ S  R   W    +G
Sbjct: 412 RTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVG 471

Query: 263 WGVPSTFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRI 318
           +GVP+    +   +  H   YG    CW  ++    W   GP+      N +LFI +  I
Sbjct: 472 YGVPAVTVAISAASWPHL--YGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWI 529

Query: 319 LLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGS 378
           L +KL   +   S       LA      + + G  + +          +V      ++ S
Sbjct: 530 LKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCL-GLLQVGPAAQVMAYLFTIINS 588

Query: 379 FQGFVVAILYCFLNGEVQAELRRKWRR 405
            QGF + ++YC L+ +VQ +  +KW R
Sbjct: 589 LQGFFIFLVYCLLSQQVQKQY-QKWFR 614


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 68/272 (25%), Positives = 118/272 (43%), Gaps = 23/272 (8%)

Query: 148  IGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQ 207
            +G  +SL  L +       FR L   RN IH +L I+  + A  +F+  +          
Sbjct: 840  VGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFI-AEFIFLIGI---------D 889

Query: 208  CSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
             ++ ++ C        +  +A F W+ +EG+ LY +L   F SE      Y + G+  P+
Sbjct: 890  KTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPA 949

Query: 268  TFTMVWTIARIHFEDYG----CWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKL 323
              T+V   A I ++ YG    CW  +++   W   GP+   IL+N I    ++  L + +
Sbjct: 950  --TVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIF---LVITLCKMV 1004

Query: 324  RPPDIRKSDSSPYSRLARSTL---LLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQ 380
            +  +  K DSS    +    L    L+ L G+ +  F     N +  V      +  +FQ
Sbjct: 1005 KHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTW-SFGLLFINEETIVMAYLFTIFNAFQ 1063

Query: 381  GFVVAILYCFLNGEVQAELRRKWRRWHLQGVL 412
            G  + I +C L  +V+ E  + +R  +  G L
Sbjct: 1064 GVFIFIFHCALQKKVRKEYGKCFRHSYCCGGL 1095


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.461 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,185,179
Number of Sequences: 37866
Number of extensions: 794865
Number of successful extensions: 2589
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 2360
Number of HSP's gapped (non-prelim): 108
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.