Guide to the Human Genome
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Search of human proteins with 156071459

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156071459 solute carrier family 25, member 5 [Homo sapiens]        600   e-172
gi|156071462 solute carrier family 25, member A6 [Homo sapiens]       565   e-161
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade...   548   e-156
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade...   428   e-120
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ...   131   8e-31
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s...   131   8e-31
gi|48476342 solute carrier family 25, member 23 [Homo sapiens]        116   3e-26
gi|239755176 PREDICTED: similar to solute carrier family 25, mem...   115   4e-26
gi|239755174 PREDICTED: similar to solute carrier family 25, mem...   115   4e-26
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ...   115   4e-26
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ...   115   4e-26
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ...   115   4e-26
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ...   115   4e-26
gi|60460887 solute carrier family 25, member 42 [Homo sapiens]        111   7e-25
gi|21361103 solute carrier family 25, member 12 [Homo sapiens]        108   6e-24
gi|27544933 solute carrier family 25, member 16 [Homo sapiens]        105   4e-23
gi|58197562 solute carrier family 25, member 30 [Homo sapiens]        105   5e-23
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho...   104   8e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H...   104   8e-23
gi|149274607 solute carrier family 25, member 41 [Homo sapiens]       103   2e-22
gi|21687151 mitochondrial solute carrier protein [Homo sapiens]       102   3e-22
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s...   101   9e-22
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo...   101   9e-22
gi|21314739 solute carrier family 25, member 32 [Homo sapiens]         99   6e-21
gi|86198310 solute carrier family 25, member 29 [Homo sapiens]         96   5e-20
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]           94   1e-19
gi|13259541 uncoupling protein 2 [Homo sapiens]                        94   1e-19
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]           92   6e-19
gi|186928856 solute carrier family 25, member 19 [Homo sapiens]        91   2e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens]        91   2e-18

>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
          Length = 298

 Score =  600 bits (1547), Expect = e-172
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
           MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR
Sbjct: 1   MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60

Query: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120
           IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG
Sbjct: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120

Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS 180
           GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS 180

Query: 181 VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM 240
           VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM 240

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT 298
           QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
Sbjct: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT 298


>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
          Length = 298

 Score =  565 bits (1456), Expect = e-161
 Identities = 274/296 (92%), Positives = 287/296 (96%)

Query: 1   MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
           MT+ A+SFAKDFLAGG+AAAISKTAVAPIERVKLLLQVQHASKQI ADKQYKGI+DC+VR
Sbjct: 1   MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVR 60

Query: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120
           IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDK TQFW YFAGNLASG
Sbjct: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASG 120

Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS 180
           GAAGATSLCFVYPLDFARTRLAADVGK+G EREFRGLGDCLVKI KSDGI+GLYQGF+VS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVS 180

Query: 181 VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM 240
           VQGIIIYRAAYFG+YDTAKGMLPDPKNTHIV+SWMIAQTVTAVAG+ SYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMM 240

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKK 296
           QSGRKG DIMYTGT+DCWRKI RDEGGKAFFKGAWSNVLRGMGGAFVLVLYDE+KK
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKK 296


>gi|55749577 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 4 [Homo
           sapiens]
          Length = 298

 Score =  548 bits (1413), Expect = e-156
 Identities = 265/297 (89%), Positives = 281/297 (94%)

Query: 1   MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
           M D A SF KDFLAGGVAAA+SKTAVAPIERVKLLLQVQHASKQI+A+KQYKGIIDCVVR
Sbjct: 1   MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60

Query: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120
           IPKEQG LSFWRGNLANVIRYFPTQALNFAFKDKYKQ+FLGGVD+  QFW YFAGNLASG
Sbjct: 61  IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASG 120

Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVS 180
           GAAGATSLCFVYPLDFARTRLAADVGK  A+REF GLGDC++KI+KSDG++GLYQGFNVS
Sbjct: 121 GAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVS 180

Query: 181 VQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMM 240
           VQGIIIYRAAYFG+YDTAKGMLPDPKN HI +SWMIAQ+VTAVAGL SYPFDTVRRRMMM
Sbjct: 181 VQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
           QSGRKG DIMYTGT+DCWRKIA+DEG KAFFKGAWSNVLRGMGGAFVLVLYDEIKKY
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297


>gi|13775208 solute carrier family 25 (mitochondrial carrier;
           adenine nucleotide translocator), member 31 [Homo
           sapiens]
          Length = 315

 Score =  428 bits (1101), Expect = e-120
 Identities = 210/293 (71%), Positives = 244/293 (83%), Gaps = 2/293 (0%)

Query: 5   AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKE 64
           A SF KD LAGGVAAA+SKTAVAPIERVKLLLQVQ +SKQI+ + +YKG++DC+VRIP+E
Sbjct: 17  ASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPRE 76

Query: 65  QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAG 124
           QG  SFWRGNLANVIRYFPTQALNFAFKDKYKQ+F+ GV+K  QFW +F  NLASGGAAG
Sbjct: 77  QGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAG 136

Query: 125 ATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGI 184
           ATSLC VYPLDFARTRL  D+GK   ER+F+GLGDC++KI KSDGI GLYQGF VSVQGI
Sbjct: 137 ATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGI 196

Query: 185 IIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244
           I+YRA+YFG YDT KG+LP PK T  ++S+ IAQ VT  +G+ SYPFDTVRRRMMMQSG 
Sbjct: 197 IVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256

Query: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
                 Y GTLDC+ KI + EG  +FF+GA+SNVLRG GGA VLVLYD+IK++
Sbjct: 257 --AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEF 307


>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
           sapiens]
          Length = 477

 Score =  131 bits (329), Expect = 8e-31
 Identities = 90/293 (30%), Positives = 152/293 (51%), Gaps = 24/293 (8%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  LAGG+A A+S+T+ AP++R+K+++QV H SK   +DK    I     ++ KE G+ S
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 249

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NVI+  P  A+ F   ++YK++      K   F  + +G++     AGAT+  
Sbjct: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 304

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
           F+YP++  +TRLA  VGK G   ++ G+ DC  KI K +G+   Y+G+  ++ GII Y  
Sbjct: 305 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359

Query: 190 AYFGIYDTAK-----GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244
               +Y+  K         D  N  +++        +    L SYP   VR RM  Q+  
Sbjct: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419

Query: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
           +G+  +    +  +R+I   EG    ++G   N ++ +    +  V+Y+ +K+
Sbjct: 420 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 16/194 (8%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F++G +A A ++T + P+E +K  L V           QY GI DC  +I K +G+ +F+
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 344

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC-- 129
           +G + N++   P   ++ A  +  K  +L    K +       G +   G    +S C  
Sbjct: 345 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 400

Query: 130 -FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
              YPL   RTR+ A     G+ +    +     +I   +GI GLY+G   +   ++   
Sbjct: 401 LASYPLALVRTRMQAQAMLEGSPQ--LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAV 458

Query: 189 AAYFGIYDTAKGML 202
              + +Y+  K  L
Sbjct: 459 GISYVVYENMKQTL 472


>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
           sapiens]
          Length = 458

 Score =  131 bits (329), Expect = 8e-31
 Identities = 90/293 (30%), Positives = 152/293 (51%), Gaps = 24/293 (8%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  LAGG+A A+S+T+ AP++R+K+++QV H SK   +DK    I     ++ KE G+ S
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 230

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NVI+  P  A+ F   ++YK++      K   F  + +G++     AGAT+  
Sbjct: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 285

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
           F+YP++  +TRLA  VGK G   ++ G+ DC  KI K +G+   Y+G+  ++ GII Y  
Sbjct: 286 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 340

Query: 190 AYFGIYDTAK-----GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244
               +Y+  K         D  N  +++        +    L SYP   VR RM  Q+  
Sbjct: 341 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 400

Query: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
           +G+  +    +  +R+I   EG    ++G   N ++ +    +  V+Y+ +K+
Sbjct: 401 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 16/194 (8%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F++G +A A ++T + P+E +K  L V           QY GI DC  +I K +G+ +F+
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 325

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC-- 129
           +G + N++   P   ++ A  +  K  +L    K +       G +   G    +S C  
Sbjct: 326 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 381

Query: 130 -FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
              YPL   RTR+ A     G+ +    +     +I   +GI GLY+G   +   ++   
Sbjct: 382 LASYPLALVRTRMQAQAMLEGSPQ--LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAV 439

Query: 189 AAYFGIYDTAKGML 202
              + +Y+  K  L
Sbjct: 440 GISYVVYENMKQTL 453


>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
          Length = 468

 Score =  116 bits (290), Expect = 3e-26
 Identities = 86/294 (29%), Positives = 147/294 (50%), Gaps = 26/294 (8%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           K  +AG VA A+S+T  AP++R+K+ +QV HASK          I+  +  +  E G+ S
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQV-HASK-----TNRLNILGGLRSMVLEGGIRS 240

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  LG      Q  L+      +G  AGAT+  
Sbjct: 241 LWRGNGINVLKIAPESAIKFMAYEQIKRAILG-----QQETLHVQERFVAGSLAGATAQT 295

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TRL   + + G   +++GL DC  +I + +G +  Y+G+  +V GII Y  
Sbjct: 296 IIYPMEVLKTRLT--LRRTG---QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350

Query: 190 AYFGIYDTAKG-----MLPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMMQSG 243
               +Y+T K         D  +  I++  +   T+++  G + SYP   VR RM  Q+ 
Sbjct: 351 IDLAVYETLKNWWLQQYSHDSADPGILV-LLACGTISSTCGQIASYPLALVRTRMQAQAS 409

Query: 244 RKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
            +G   +    L   R I   EG +  ++G   N ++ +    +  V+Y+ +K+
Sbjct: 410 IEGGPQL--SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461



 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 55/194 (28%), Positives = 89/194 (45%), Gaps = 16/194 (8%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F+AG +A A ++T + P+E +K  L ++          QYKG++DC  RI + +G  +F+
Sbjct: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG-------QYKGLLDCARRILEREGPRAFY 335

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWLYFAGNLASGGAAGATSLC 129
           RG L NV+   P   ++ A  +  K  +L     D      L     LA G  +      
Sbjct: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVL---LACGTISSTCGQI 392

Query: 130 FVYPLDFARTRLAADVG-KAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
             YPL   RTR+ A    + G +    GL   L  I   +G++GLY+G   +   +I   
Sbjct: 393 ASYPLALVRTRMQAQASIEGGPQLSMLGL---LRHILSQEGMRGLYRGIAPNFMKVIPAV 449

Query: 189 AAYFGIYDTAKGML 202
           +  + +Y+  K  L
Sbjct: 450 SISYVVYENMKQAL 463


>gi|239755176 PREDICTED: similar to solute carrier family 25, member
           25 isoform 2 [Homo sapiens]
          Length = 469

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461


>gi|239755174 PREDICTED: similar to solute carrier family 25, member
           25 isoform 1 [Homo sapiens]
          Length = 503

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 275

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 330

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 331 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 441

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 442 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495


>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
           sapiens]
          Length = 489

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 261

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 262 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 316

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 317 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 371

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 372 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 427

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 428 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481


>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
           sapiens]
          Length = 469

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461


>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
           sapiens]
          Length = 366

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 85  RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 138

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 139 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 193

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 194 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 248

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 249 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 304

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 305 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358


>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
           sapiens]
          Length = 503

 Score =  115 bits (289), Expect = 4e-26
 Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           +  +AGG A A+S+T  AP++R+K+L+QV HAS+         GI+    ++ +E G  S
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 275

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F   ++ K+  L G D+ T   L     L +G  AGA +  
Sbjct: 276 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 330

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            +YP++  +TR+A  + K G   ++ G+ DC  +I   +G+   Y+G+  ++ GII Y  
Sbjct: 331 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385

Query: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
               +Y+T K            DP     V   +   T+++  G L SYP   VR RM  
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 441

Query: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
           Q+  +G   +   +L  ++ I R EG    ++G   N ++ +    +  V+Y+ +K
Sbjct: 442 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495


>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
          Length = 318

 Score =  111 bits (278), Expect = 7e-25
 Identities = 84/276 (30%), Positives = 133/276 (48%), Gaps = 25/276 (9%)

Query: 13  LAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWR 72
           L G +A A++KTAVAP++R K++ QV  +SK+ +A + ++ +    +     +G LS WR
Sbjct: 38  LPGALAGALAKTAVAPLDRTKIIFQV--SSKRFSAKEAFRVLYYTYLN----EGFLSLWR 91

Query: 73  GNLANVIRYFPTQALNFAFKDKYKQI---FLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
           GN A ++R  P  A+ F+  ++YK+I   + G   +    W      L +G  AG T+  
Sbjct: 92  GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW----PRLFAGALAGTTAAS 147

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
             YPLD  R R+A        +  +  +    ++I + +G+K LY GF  +V G+I Y  
Sbjct: 148 LTYPLDLVRARMAVT-----PKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAG 202

Query: 190 AYFGIYDTAKGMLPD--PKNTHIVISWMIAQTVTAVAGLT-SYPFDTVRRRMMMQSGRKG 246
             F  Y+T K +  +   +        MI      + G + SYP D VRRRM        
Sbjct: 203 LSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGY 262

Query: 247 TDIMYTGTLDCWRKIARDEGG-KAFFKGAWSNVLRG 281
                  TL   R I R+EG  +  +KG   N ++G
Sbjct: 263 PRASIARTL---RTIVREEGAVRGLYKGLSMNWVKG 295



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 28/176 (15%)

Query: 116 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 175
           +L  G  AGA +   V PLD  +        +  A+  FR     L   Y ++G   L++
Sbjct: 36  SLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR----VLYYTYLNEGFLSLWR 91

Query: 176 GFNVSVQGIIIYRAAYFGIYDTAKGML------------PDPKNTHIVISWMIAQTVTAV 223
           G + ++  ++ Y A  F  ++  K +L            P P+       +  A   T  
Sbjct: 92  GNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPR------LFAGALAGTTA 145

Query: 224 AGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVL 279
           A LT YP D VR RM +         MY+     + +I+R+EG K  + G    VL
Sbjct: 146 ASLT-YPLDLVRARMAVTPKE-----MYSNIFHVFIRISREEGLKTLYHGFMPTVL 195


>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
          Length = 678

 Score =  108 bits (270), Expect = 6e-24
 Identities = 81/289 (28%), Positives = 131/289 (45%), Gaps = 17/289 (5%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F  G VA A+  TAV PI+ VK  +Q Q  S  +  +  YK   DC  ++ + +G    +
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFV 131
           RG +  +I   P +A+     D  +  F      R    +     + +GG AG + + F 
Sbjct: 390 RGLIPQLIGVAPEKAIKLTVNDFVRDKF-----TRRDGSVPLPAEVLAGGCAGGSQVIFT 444

Query: 132 YPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAY 191
            PL+  + RL        A     G     + + +  GI GLY+G        I + A Y
Sbjct: 445 NPLEIVKIRLQV------AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIY 498

Query: 192 FGIYDTAKGMLPDPKNTHI-VISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGTDI 249
           F +Y   K +L D +N H+  ++ + A  +  V A     P D ++ R  +Q   +    
Sbjct: 499 FPVYAHCKLLLAD-ENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTR--LQVAARAGQT 555

Query: 250 MYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGG-AFVLVLYDEIKKY 297
            Y+G +DC+RKI R+EG  AF+KG  + V R        LV Y+ ++++
Sbjct: 556 TYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRW 604



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 27/180 (15%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D +V    + LAGG A         P+E VK+ LQV   + +IT   +   +      + 
Sbjct: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----NVL 472

Query: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIF------LGGVDKRTQFWLYFAGN 116
           ++ G+   ++G  A  +R  P  A+ F      K +       +GG++            
Sbjct: 473 RDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL----------- 521

Query: 117 LASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQG 176
           LA+G  AG  +   V P D  +TRL   V     +  + G+ DC  KI + +G    ++G
Sbjct: 522 LAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPSAFWKG 579


>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
          Length = 332

 Score =  105 bits (263), Expect = 4e-23
 Identities = 76/250 (30%), Positives = 115/250 (46%), Gaps = 36/250 (14%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQV-QHASKQITADKQYKGIIDCVVRIPKEQGVL 68
           + FLAGG+A   +KT VAP++RVK+LLQ   H  K +       G+   +  +P+++G L
Sbjct: 38  RSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHL-------GVFSALRAVPQKEGFL 90

Query: 69  SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWLYFAGNLASGGAAGAT 126
             ++GN A +IR FP  A+ F   + YK +     G+             L +G  AG T
Sbjct: 91  GLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVH-------RLMAGSMAGMT 143

Query: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIY-KSDGIKGLYQGFNVSVQGII 185
           ++   YPLD  R RLA  V     E  + G+      IY K  G  G Y+G   ++ G+ 
Sbjct: 144 AVICTYPLDMVRVRLAFQV---KGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMA 200

Query: 186 IYRAAYFGIYDTAKGM----------LPDPKNTHIV-----ISWMIAQTVTAVAGLTSYP 230
            Y    F  + T K +           P   N +++     ++ +      A+A   SYP
Sbjct: 201 PYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYP 260

Query: 231 FDTVRRRMMM 240
           FD  RRRM +
Sbjct: 261 FDVTRRRMQL 270



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 51/198 (25%), Positives = 79/198 (39%), Gaps = 17/198 (8%)

Query: 13  LAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRI-PKEQGVLSFW 71
           +AG +A   +     P++ V++ L  Q     +  +  Y GII     I  KE G   F+
Sbjct: 135 MAGSMAGMTAVICTYPLDMVRVRLAFQ-----VKGEHSYTGIIHAFKTIYAKEGGFFGFY 189

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLGGV---------DKRTQFWLYFAGNLASGGA 122
           RG +  ++   P   ++F      K + L            D      L    NL  GG 
Sbjct: 190 RGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGV 249

Query: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGI-KGLYQGFNVSV 181
           AGA +    YP D  R R+         E+    + D +  +Y   GI KGLY+G +++ 
Sbjct: 250 AGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLT-MRDTMKYVYGHHGIRKGLYRGLSLNY 308

Query: 182 QGIIIYRAAYFGIYDTAK 199
              I  +A  F  Y+  K
Sbjct: 309 IRCIPSQAVAFTTYELMK 326



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 52/185 (28%), Positives = 84/185 (45%), Gaps = 19/185 (10%)

Query: 101 GGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDC 160
           GG   R  F  Y+  +  +GG AG  +   V PLD  +  L A         +  G+   
Sbjct: 26  GGPTTRRDF--YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAH----NHHYKHLGVFSA 79

Query: 161 LVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTV 220
           L  + + +G  GLY+G    +  I  Y A  F  ++  K ++     T + IS  + + +
Sbjct: 80  LRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLI----TTKLGISGHVHRLM 135

Query: 221 T-AVAGLT----SYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGG-KAFFKGA 274
             ++AG+T    +YP D VR R+  Q   KG +  YTG +  ++ I   EGG   F++G 
Sbjct: 136 AGSMAGMTAVICTYPLDMVRVRLAFQV--KG-EHSYTGIIHAFKTIYAKEGGFFGFYRGL 192

Query: 275 WSNVL 279
              +L
Sbjct: 193 MPTIL 197



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 11  DFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS- 69
           + L GGVA AI++T   P +  +  +Q+     +    ++   + D +  +    G+   
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEF---EKCLTMRDTMKYVYGHHGIRKG 299

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIF 99
            +RG   N IR  P+QA+ F   +  KQ F
Sbjct: 300 LYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329


>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
          Length = 291

 Score =  105 bits (262), Expect = 5e-23
 Identities = 82/296 (27%), Positives = 134/296 (45%), Gaps = 23/296 (7%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK-QYKGIIDCVVRIPKEQGVL 68
           K F+ GG+A+  ++    PI+  K  LQ+Q  +      + +Y+G++  +VRI +E+G+ 
Sbjct: 7   KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66

Query: 69  SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
           + + G    ++R      +        K++F+   +  T        N+  G  +G  S 
Sbjct: 67  ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-----LPINVICGILSGVISS 121

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
               P D  + R+ A            G+    + IY+ +G +GL++G +++ Q   I  
Sbjct: 122 TIANPTDVLKIRMQAQSNTIQG-----GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176

Query: 189 AAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
                +YD  K      G++ D   TH + S+    T      L S P D VR RMM Q 
Sbjct: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSF----TCGLAGALASNPVDVVRTRMMNQR 232

Query: 243 G-RKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
             R G    YTGTLDC  +  ++EG  A +KG W N LR G       V Y+++KK
Sbjct: 233 VLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 16  GVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNL 75
           G+A A++     P++ V+  +  Q   +       Y G +DC+++  K +G  + ++G  
Sbjct: 211 GLAGALASN---PVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLLQTWKNEGFFALYKGFW 266

Query: 76  ANVIRYFPTQALNFAFKDKYKQIFL 100
            N +R  P   + F   ++ K++ L
Sbjct: 267 PNWLRLGPWNIIFFVTYEQLKKLDL 291


>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
           sapiens]
          Length = 325

 Score =  104 bits (260), Expect = 8e-23
 Identities = 83/295 (28%), Positives = 134/295 (45%), Gaps = 22/295 (7%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK-QYKGIIDCVVRIPKEQGVL 68
           K F+ GG+A+ +++    P++  K  LQVQ  S      + +Y+G+   + RI KE+GVL
Sbjct: 42  KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101

Query: 69  SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
           + + G    ++R      +        K++F+  ++  T        N+  G  +G  S 
Sbjct: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 156

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
               P D  + R+ A     G+  +   +G   + IY+ +G +GL++G   + Q   I  
Sbjct: 157 TIANPTDVLKIRMQAQ----GSLFQGSMIGS-FIDIYQQEGTRGLWRGVVPTAQRAAIVV 211

Query: 189 AAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
                +YD  K      GM+ D   TH V S+    T      L S P D VR RMM Q 
Sbjct: 212 GVELPVYDITKKHLILSGMMGDTILTHFVSSF----TCGLAGALASNPVDVVRTRMMNQR 267

Query: 243 GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
              G   +Y GT+D   K+ + EG  A +KG W N LR G       + Y+++K+
Sbjct: 268 AIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322


>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
           sapiens]
          Length = 322

 Score =  104 bits (260), Expect = 8e-23
 Identities = 83/295 (28%), Positives = 134/295 (45%), Gaps = 22/295 (7%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK-QYKGIIDCVVRIPKEQGVL 68
           K F+ GG+A+ +++    P++  K  LQVQ  S      + +Y+G+   + RI KE+GVL
Sbjct: 39  KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 98

Query: 69  SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
           + + G    ++R      +        K++F+  ++  T        N+  G  +G  S 
Sbjct: 99  ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 153

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
               P D  + R+ A     G+  +   +G   + IY+ +G +GL++G   + Q   I  
Sbjct: 154 TIANPTDVLKIRMQAQ----GSLFQGSMIGS-FIDIYQQEGTRGLWRGVVPTAQRAAIVV 208

Query: 189 AAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
                +YD  K      GM+ D   TH V S+    T      L S P D VR RMM Q 
Sbjct: 209 GVELPVYDITKKHLILSGMMGDTILTHFVSSF----TCGLAGALASNPVDVVRTRMMNQR 264

Query: 243 GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
              G   +Y GT+D   K+ + EG  A +KG W N LR G       + Y+++K+
Sbjct: 265 AIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319


>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
          Length = 370

 Score =  103 bits (257), Expect = 2e-22
 Identities = 79/295 (26%), Positives = 138/295 (46%), Gaps = 30/295 (10%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           K  L+G +A A+S+T  AP++R K+ +QV  +    T       ++  +  + +E G  S
Sbjct: 94  KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFT------NLLGGLQSMVQEGGFRS 147

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            WRGN  NV++  P  A+ F+  ++ K  F G      Q    F   L +G  A A S  
Sbjct: 148 LWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG-----IQGSPPFQERLLAGSLAVAISQT 202

Query: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
            + P++  +TRL   + + G   +++GL DC  +I + +G + LY+G+  ++ GII Y  
Sbjct: 203 LINPMEVLKTRLT--LRRTG---QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYAC 257

Query: 190 AYFGIYDTAKGM-------LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
               +Y+  +         + DP     ++S       T    + SYP   VR RM  Q 
Sbjct: 258 TDLAVYEMLQCFWVKSGRDMGDPSG---LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQD 314

Query: 243 GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGM-GGAFVLVLYDEIKK 296
             +G++    G L   ++I   +G    ++G    +L+ +  G    V+Y+ +KK
Sbjct: 315 TVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 51/196 (26%), Positives = 88/196 (44%), Gaps = 14/196 (7%)

Query: 8   FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGV 67
           F +  LAG +A AIS+T + P+E +K  L ++          QYKG++DC  +I + +G 
Sbjct: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTG-------QYKGLLDCARQILQREGT 238

Query: 68  LSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKRTQFWLYFAGNLASGGAAGAT 126
            + +RG L N++   P    + A  +  +  ++  G D      L    ++      G  
Sbjct: 239 RALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQM 298

Query: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIII 186
           +    YPL   RTR+ A     G+    RG+   L +I    G  GLY+G   ++  ++ 
Sbjct: 299 A---SYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRGMTPTLLKVLP 352

Query: 187 YRAAYFGIYDTAKGML 202
                + +Y+  K  L
Sbjct: 353 AGGISYVVYEAMKKTL 368


>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
          Length = 341

 Score =  102 bits (255), Expect = 3e-22
 Identities = 74/283 (26%), Positives = 133/283 (46%), Gaps = 19/283 (6%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D  ++  +  L  G+A  +S +  AP+E   +L QV             +G      R+ 
Sbjct: 7   DGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVG------VVRGHARGPWATGHRVW 60

Query: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122
           + +G+ + W+GN    +R FP  A+  A   K+  +F   +   +Q+    AG+L     
Sbjct: 61  RAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSL----- 115

Query: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQ 182
           AG  S    YP D  +TRL   + +   E  +RGL      IY+ +G   LY+G +++V 
Sbjct: 116 AGMVSTIVTYPTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVV 172

Query: 183 GIIIYRAAYFGIYDTAKGMLPDPKNT-HIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQ 241
           G + + A    +Y   + +   P++   +  ++       AV    S+PF+TV+R+M  Q
Sbjct: 173 GALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQ 232

Query: 242 S----GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
           S       G D+ ++G +DC+R+I + +G    + G  +N+L+
Sbjct: 233 SPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 14/198 (7%)

Query: 6   VSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQ 65
           +S     +AG +A  +S     P + +K  L +Q+       +  Y+G++     I +++
Sbjct: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNI-----LEPSYRGLLHAFSTIYQQE 158

Query: 66  GVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGA 125
           G L+ +RG    V+   P  A +       ++I+ G    R QF L    N A+   A A
Sbjct: 159 GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNG---PRDQFSL--PQNFANVCLAAA 213

Query: 126 TSLCFVYPLDFARTRLAADVG----KAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181
            +    +P +  + ++ A         G +  F G  DC  +I K+ G+ GL+ G   ++
Sbjct: 214 VTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273

Query: 182 QGIIIYRAAYFGIYDTAK 199
             I+ Y    F  ++  K
Sbjct: 274 LKIVPYFGIMFSTFEFCK 291



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 2/96 (2%)

Query: 7   SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ--HASKQITADKQYKGIIDCVVRIPKE 64
           S  ++F    +AAA+++T   P E VK  +Q Q  +       D  + G +DC  +I K 
Sbjct: 200 SLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKA 259

Query: 65  QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL 100
           QGVL  W G  AN+++  P   + F+  +  K+I L
Sbjct: 260 QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295


>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
           sapiens]
          Length = 675

 Score =  101 bits (251), Expect = 9e-22
 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 20/273 (7%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F  G VA A+  TAV PI+ VK  +Q Q ++     +  YK   DC  ++ + +G    +
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFL---GGVDKRTQFWLYFAGNLASGGAAGATSL 128
           RG L  ++   P +A+     D  +  F+   G V          A  + +GG AG + +
Sbjct: 392 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP--------LAAEILAGGCAGGSQV 443

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
            F  PL+  + RL        A     G     + + +  G  G+Y+G        I + 
Sbjct: 444 IFTNPLEIVKIRLQV------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFS 497

Query: 189 AAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGT 247
           A YF  Y   K    +        S ++A  +  + A     P D ++ R  +Q   +  
Sbjct: 498 AIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQVAARAG 555

Query: 248 DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
              Y+G +DC+RKI R+EG KA +KGA + V R
Sbjct: 556 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 588



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 48/179 (26%), Positives = 75/179 (41%), Gaps = 15/179 (8%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D +V  A + LAGG A         P+E VK+ LQV   + +IT   +   +      + 
Sbjct: 423 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVV 474

Query: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122
           ++ G    ++G  A  +R  P  A+ F      K  F     + +   L     L +G  
Sbjct: 475 RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-----LLAGAI 529

Query: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181
           AG  +   V P D  +TRL   V     +  + G+ DC  KI + +G K L++G    V
Sbjct: 530 AGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 586



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D  VS     LAG +A   + + V P + +K  LQV   + Q T    Y G+IDC  +I 
Sbjct: 515 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKIL 570

Query: 63  KEQGVLSFWRGNLANVIR---YFPTQALNFAFKDKYKQIFLGGV 103
           +E+G  + W+G  A V R    F    L +    ++  I  GGV
Sbjct: 571 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 614


>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
           sapiens]
          Length = 676

 Score =  101 bits (251), Expect = 9e-22
 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 20/273 (7%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           F  G VA A+  TAV PI+ VK  +Q Q ++     +  YK   DC  ++ + +G    +
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFL---GGVDKRTQFWLYFAGNLASGGAAGATSL 128
           RG L  ++   P +A+     D  +  F+   G V          A  + +GG AG + +
Sbjct: 393 RGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVP--------LAAEILAGGCAGGSQV 444

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
            F  PL+  + RL        A     G     + + +  G  G+Y+G        I + 
Sbjct: 445 IFTNPLEIVKIRLQV------AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFS 498

Query: 189 AAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAV-AGLTSYPFDTVRRRMMMQSGRKGT 247
           A YF  Y   K    +        S ++A  +  + A     P D ++ R  +Q   +  
Sbjct: 499 AIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR--LQVAARAG 556

Query: 248 DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
              Y+G +DC+RKI R+EG KA +KGA + V R
Sbjct: 557 QTTYSGVIDCFRKILREEGPKALWKGAGARVFR 589



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 48/179 (26%), Positives = 75/179 (41%), Gaps = 15/179 (8%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D +V  A + LAGG A         P+E VK+ LQV   + +IT   +   +      + 
Sbjct: 424 DGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQV---AGEITTGPRVSAL-----SVV 475

Query: 63  KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122
           ++ G    ++G  A  +R  P  A+ F      K  F     + +   L     L +G  
Sbjct: 476 RDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSL-----LLAGAI 530

Query: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181
           AG  +   V P D  +TRL   V     +  + G+ DC  KI + +G K L++G    V
Sbjct: 531 AGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARV 587



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 3   DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
           D  VS     LAG +A   + + V P + +K  LQV   + Q T    Y G+IDC  +I 
Sbjct: 516 DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT----YSGVIDCFRKIL 571

Query: 63  KEQGVLSFWRGNLANVIR---YFPTQALNFAFKDKYKQIFLGGV 103
           +E+G  + W+G  A V R    F    L +    ++  I  GGV
Sbjct: 572 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGV 615


>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
          Length = 315

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 86/299 (28%), Positives = 137/299 (45%), Gaps = 27/299 (9%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           ++ +AG     +S  A+ P++ VK+   V   S  +    +Y GI+ C+  I K  G+  
Sbjct: 24  ENLIAGVSGGVLSNLALHPLDLVKIRFAV---SDGLELRPKYNGILHCLTTIWKLDGLRG 80

Query: 70  FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
            ++G   N+     +  L F F +  K     G  +R +   Y    L S   AGA +LC
Sbjct: 81  LYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEY----LVSAAEAGAMTLC 136

Query: 130 FVYPLDFARTRLAA--DVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIY 187
              PL   +TRL    D       R+++G+ D LVKIYK +G++GLY+GF   + G   +
Sbjct: 137 ITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFG-TSH 195

Query: 188 RAAYFGIYDTAK-------GMLPDPK-NTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMM 239
            A  F  Y+  K         LP+ + +T   IS      + AVA   +YP+  VR R+ 
Sbjct: 196 GALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVA--ATYPYQVVRARLQ 253

Query: 240 MQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKKY 297
            Q       + Y+G +D   K  R EG   F+KG   N++R      +  V+Y+ +  +
Sbjct: 254 DQ------HMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHF 306



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 12/92 (13%)

Query: 19  AAISK----TAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGN 74
           AA+SK     A  P + V+  LQ QH          Y G+ID + +  +++GV  F++G 
Sbjct: 231 AALSKIFAVAATYPYQVVRARLQDQHMF--------YSGVIDVITKTWRKEGVGGFYKGI 282

Query: 75  LANVIRYFPTQALNFAFKDKYKQIFLGGVDKR 106
             N+IR  P   + F   +      L   +KR
Sbjct: 283 APNLIRVTPACCITFVVYENVSHFLLDLREKR 314


>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
          Length = 303

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 83/274 (30%), Positives = 126/274 (45%), Gaps = 20/274 (7%)

Query: 9   AKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVL 68
           A DFLAG            P + VK+ LQVQ   K      QY+G + C   I K++ VL
Sbjct: 2   ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKP-----QYRGTLHCFKSIIKQESVL 56

Query: 69  SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
             ++G  + ++      AL F  +    +  LG      QF         +G AAGA   
Sbjct: 57  GLYKGLGSPLMGLTFINALVFGVQGNTLRA-LGHDSPLNQF--------LAGAAAGAIQC 107

Query: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
               P++ A+TRL   +  AG  R ++G  DCL +IY  +G++G+ +G   ++       
Sbjct: 108 VICCPMELAKTRL--QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSF 165

Query: 189 AAYFGIYDTAKGMLP-DPKNTHIVISWMIAQ-TVTAVAGLTSYPFDTVRRRMMMQSGRKG 246
             YF  YD     L  +P +  +V   ++A  T   V+ L++YP D V+ R+    G +G
Sbjct: 166 GVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRG 224

Query: 247 TDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
               Y G LDC  +  R EG + F +G  S +LR
Sbjct: 225 AP-RYRGILDCVHQSYRAEGWRVFTRGLASTLLR 257



 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 10/181 (5%)

Query: 12  FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           FLAG  A AI      P+E  K  LQ+Q A    T    YKG +DC+ +I   +G+    
Sbjct: 96  FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPART----YKGSLDCLAQIYGHEGLRGVN 151

Query: 72  RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFV 131
           RG ++ ++R  P+  + F   D   +    G +   +  L     L +GG +G  S    
Sbjct: 152 RGMVSTLLRETPSFGVYFLTYDALTRAL--GCEPGDR--LLVPKLLLAGGTSGIVSWLST 207

Query: 132 YPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAY 191
           YP+D  ++RL AD G  GA R +RG+ DC+ + Y+++G +   +G   ++       AA 
Sbjct: 208 YPVDVVKSRLQAD-GLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAAT 265

Query: 192 F 192
           F
Sbjct: 266 F 266



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 10  KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
           K  LAGG +  +S  +  P++ VK  LQ       +    +Y+GI+DCV +  + +G   
Sbjct: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADG----LRGAPRYRGILDCVHQSYRAEGWRV 246

Query: 70  FWRGNLANVIRYFPTQALNFA 90
           F RG  + ++R FP  A  FA
Sbjct: 247 FTRGLASTLLRAFPVNAATFA 267


>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
          Length = 312

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 75/307 (24%), Positives = 133/307 (43%), Gaps = 26/307 (8%)

Query: 2   TDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK--QYKGIIDCVV 59
           +D   + A  FL  G AA  +     P++  K+ LQ+Q  ++ +   +  QY+G++  ++
Sbjct: 7   SDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTIL 66

Query: 60  RIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKRTQFWLYFAGNLA 118
            + + +G  S + G +A + R     ++     D  KQ++   G D  +         + 
Sbjct: 67  TMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-----LTTRIL 121

Query: 119 SGGAAGATSLCFVYPLDFARTRLAADV--GKAGAEREFRGLGDCLVKIYKSDGIKGLYQG 176
           +G   GA ++    P D  + R  A +  G + ++R++ G  D    I + +G++GL++G
Sbjct: 122 AGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKG 181

Query: 177 FNVSVQGIIIYRAAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYP 230
              ++    I   A    YD  K       +L D    H V ++      T VA     P
Sbjct: 182 TLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVAS----P 237

Query: 231 FDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLV 289
            D V+ R M           Y   LDC  K+   EG  AF+KG   + LR G     + V
Sbjct: 238 VDVVKTRYM-----NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFV 292

Query: 290 LYDEIKK 296
            Y+++K+
Sbjct: 293 TYEQLKR 299



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 9/196 (4%)

Query: 7   SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQG 66
           S     LAG    A++ T   P + VK+  Q         +D++Y G +D    I +E+G
Sbjct: 115 SLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEG 174

Query: 67  VLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGAT 126
           V   W+G L N++R            D  K+  L        F  +F     S   AG  
Sbjct: 175 VRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHF----VSAFGAGFC 230

Query: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIII 186
           +     P+D  +TR       +   + F  L DC++K+   +G    Y+GF  S   +  
Sbjct: 231 ATVVASPVDVVKTRYM----NSPPGQYFSPL-DCMIKMVAQEGPTAFYKGFTPSFLRLGS 285

Query: 187 YRAAYFGIYDTAKGML 202
           +    F  Y+  K  L
Sbjct: 286 WNVVMFVTYEQLKRAL 301



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 200 GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTD----IMYTGTL 255
           G+ P      + + ++ A T    A L ++P DT + R+ +Q   +       + Y G L
Sbjct: 3   GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVL 62

Query: 256 DCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLV-LYDEIKK 296
                + R EG  + + G  + + R M  A + + LYD +K+
Sbjct: 63  GTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQ 104


>gi|13259541 uncoupling protein 2 [Homo sapiens]
          Length = 309

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 25/305 (8%)

Query: 2   TDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASK---QITADKQYKGIIDCV 58
           TD   +    FL  G AA I+     P++  K+ LQ+Q  S+   + TA  QY+G++  +
Sbjct: 7   TDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTI 66

Query: 59  VRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLA 118
           + + + +G  S + G +A + R     ++     D  KQ +  G +  +         L 
Sbjct: 67  LTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAS-----IGSRLL 121

Query: 119 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFN 178
           +G   GA ++    P D  + R  A   +AG  R ++   +    I + +G +GL++G +
Sbjct: 122 AGSTTGALAVAVAQPTDVVKVRFQAQ-ARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTS 180

Query: 179 VSVQGIIIYRAAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFD 232
            +V    I   A    YD  K       ++ D    H   ++      T +A     P D
Sbjct: 181 PNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIAS----PVD 236

Query: 233 TVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLY 291
            V+ R M  +  +     Y+    C   + + EG +AF+KG   + LR G     + V Y
Sbjct: 237 VVKTRYMNSALGQ-----YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTY 291

Query: 292 DEIKK 296
           +++K+
Sbjct: 292 EQLKR 296



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 42/196 (21%), Positives = 70/196 (35%), Gaps = 12/196 (6%)

Query: 7   SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQG 66
           S     LAG    A++     P + VK+  Q Q    +    ++Y+  ++    I +E+G
Sbjct: 115 SIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQ---ARAGGGRRYQSTVNAYKTIAREEG 171

Query: 67  VLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGAT 126
               W+G   NV R            D  K   L           +F     S   AG  
Sbjct: 172 FRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFT----SAFGAGFC 227

Query: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIII 186
           +     P+D  +TR         A  ++   G C + + + +G +  Y+GF  S   +  
Sbjct: 228 TTVIASPVDVVKTRYMNS-----ALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGS 282

Query: 187 YRAAYFGIYDTAKGML 202
           +    F  Y+  K  L
Sbjct: 283 WNVVMFVTYEQLKRAL 298


>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
          Length = 323

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 75/306 (24%), Positives = 128/306 (41%), Gaps = 40/306 (13%)

Query: 1   MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
           M D  +S     + GG+A  I  T V PI+  K  LQ Q   +++     Y  + DC+++
Sbjct: 1   MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRV-----YTSMSDCLIK 55

Query: 61  IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASG 120
             + +G    +RG   N+    P +A+  A  D ++        K T         + +G
Sbjct: 56  TVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLT-----LLKEMLAG 110

Query: 121 GAAGATSLCFVYPLDFARTRLAADVGKAGAEREF-----------------------RGL 157
             AG   +    P++  + +L  D G+  A+R+                        R  
Sbjct: 111 CGAGTCQVIVTTPMEMLKIQLQ-DAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPT 169

Query: 158 GDCLVK-IYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAK--GMLPDPKNTHIVISW 214
              L + + +S GI GLY+G   ++   + +   YF ++      G     + +   +S+
Sbjct: 170 ATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSF 229

Query: 215 MIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGT-DIMYTGTLDCWRKIARDEGGKAFFKG 273
           +      + A +   P D V+ R+  QS ++G  +  Y+G LDC RKI R EG  AF KG
Sbjct: 230 LAGCVAGSAAAVAVNPCDVVKTRL--QSLQRGVNEDTYSGILDCARKILRHEGPSAFLKG 287

Query: 274 AWSNVL 279
           A+   L
Sbjct: 288 AYCRAL 293


>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 67/293 (22%), Positives = 133/293 (45%), Gaps = 21/293 (7%)

Query: 13  LAGGVAAAISKTAVAPIERVKLLLQVQHAS-KQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           +AG V+  +++  ++P + +K+  Q+QH    +     +Y GI+    +I +E+G  +FW
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 72  RGNLANVIRYFPTQALNF-AFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCF 130
           +G++   I      A+ F +F+   + +  G V    +F ++F      GG A   +   
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV----CGGLAACMATLT 135

Query: 131 VYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAA 190
           V+P+D  RTR AA     G  + +  L   +  +Y+S+G +  Y+G   ++  I  Y   
Sbjct: 136 VHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191

Query: 191 YFGIYDTAKGMLP-----DPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRK 245
            F  Y + K +       + K    + + +       ++   +YP D  ++R+ +     
Sbjct: 192 QFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251

Query: 246 -----GTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYD 292
                G    Y G +DC +++ + EG   FFKG   ++L+  +   F+   Y+
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 46/185 (24%), Positives = 81/185 (43%), Gaps = 18/185 (9%)

Query: 5   AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKE 64
           A  F+  F+ GG+AA ++   V P++ ++     Q         K Y  +   V  + + 
Sbjct: 115 AREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ------GEPKVYNTLRHAVGTMYRS 168

Query: 65  QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGV---DKRTQFWLYFAGNLASGG 121
           +G   F++G    +I  FP   L F+     K ++   +    K+ +       NL  G 
Sbjct: 169 EGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNE----NLQNLLCGS 224

Query: 122 AAGATSLCFVYPLDFARTRLAA---DVGKA--GAEREFRGLGDCLVKIYKSDGIKGLYQG 176
            AG  S    YPLD  + RL     +  +A  G  R ++GL DC  ++ + +G  G ++G
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284

Query: 177 FNVSV 181
            + S+
Sbjct: 285 LSPSL 289


>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
          Length = 320

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 67/293 (22%), Positives = 133/293 (45%), Gaps = 21/293 (7%)

Query: 13  LAGGVAAAISKTAVAPIERVKLLLQVQHAS-KQITADKQYKGIIDCVVRIPKEQGVLSFW 71
           +AG V+  +++  ++P + +K+  Q+QH    +     +Y GI+    +I +E+G  +FW
Sbjct: 20  VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79

Query: 72  RGNLANVIRYFPTQALNF-AFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCF 130
           +G++   I      A+ F +F+   + +  G V    +F ++F      GG A   +   
Sbjct: 80  KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV----CGGLAACMATLT 135

Query: 131 VYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAA 190
           V+P+D  RTR AA     G  + +  L   +  +Y+S+G +  Y+G   ++  I  Y   
Sbjct: 136 VHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGL 191

Query: 191 YFGIYDTAKGMLP-----DPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRK 245
            F  Y + K +       + K    + + +       ++   +YP D  ++R+ +     
Sbjct: 192 QFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251

Query: 246 -----GTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYD 292
                G    Y G +DC +++ + EG   FFKG   ++L+  +   F+   Y+
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 46/185 (24%), Positives = 81/185 (43%), Gaps = 18/185 (9%)

Query: 5   AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKE 64
           A  F+  F+ GG+AA ++   V P++ ++     Q         K Y  +   V  + + 
Sbjct: 115 AREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ------GEPKVYNTLRHAVGTMYRS 168

Query: 65  QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGV---DKRTQFWLYFAGNLASGG 121
           +G   F++G    +I  FP   L F+     K ++   +    K+ +       NL  G 
Sbjct: 169 EGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNE----NLQNLLCGS 224

Query: 122 AAGATSLCFVYPLDFARTRLAA---DVGKA--GAEREFRGLGDCLVKIYKSDGIKGLYQG 176
            AG  S    YPLD  + RL     +  +A  G  R ++GL DC  ++ + +G  G ++G
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284

Query: 177 FNVSV 181
            + S+
Sbjct: 285 LSPSL 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,909,953
Number of Sequences: 37866
Number of extensions: 389646
Number of successful extensions: 1467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 924
Number of HSP's gapped (non-prelim): 181
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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