Guide to the Human Genome
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Search of human proteins with 151101369

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]
         (200 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]        396   e-111
gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]        389   e-109
gi|21361661 COMM domain containing 4 [Homo sapiens]                    49   3e-06
gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]          39   0.004
gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]          33   0.16 
gi|239755822 PREDICTED: hypothetical protein [Homo sapiens]            31   0.80 
gi|239750319 PREDICTED: hypothetical protein [Homo sapiens]            31   0.80 
gi|239744623 PREDICTED: hypothetical protein [Homo sapiens]            31   0.80 
gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]         30   1.4  
gi|169208214 PREDICTED: similar to COMM domain containing 4 [Hom...    28   4.0  
gi|239735575 otoancorin isoform 3 [Homo sapiens]                       28   4.0  
gi|24638452 otoancorin isoform 2 [Homo sapiens]                        28   4.0  
gi|77404409 otoancorin isoform 1 [Homo sapiens]                        28   4.0  
gi|33342278 TraB domain containing [Homo sapiens]                      28   6.8  

>gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]
          Length = 200

 Score =  396 bits (1017), Expect = e-111
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MGRLHCTEDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATT 60
           MGRLHCTEDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATT
Sbjct: 1   MGRLHCTEDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATT 60

Query: 61  NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL 120
           NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL
Sbjct: 61  NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL 120

Query: 121 ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP 180
           ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP
Sbjct: 121 ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP 180

Query: 181 QFYSFLHEMERVRTSMECFC 200
           QFYSFLHEMERVRTSMECFC
Sbjct: 181 QFYSFLHEMERVRTSMECFC 200


>gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]
          Length = 199

 Score =  389 bits (1000), Expect = e-109
 Identities = 199/200 (99%), Positives = 199/200 (99%), Gaps = 1/200 (0%)

Query: 1   MGRLHCTEDPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATT 60
           MGRLHCTEDPVPEAVGGDMQQLNQLGAQ FSALTEVLFHFLTEPKEVERFLAQLSEFATT
Sbjct: 1   MGRLHCTEDPVPEAVGGDMQQLNQLGAQ-FSALTEVLFHFLTEPKEVERFLAQLSEFATT 59

Query: 61  NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL 120
           NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL
Sbjct: 60  NQISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTL 119

Query: 121 ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP 180
           ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP
Sbjct: 120 ARWAIGQTLMINQLIDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLP 179

Query: 181 QFYSFLHEMERVRTSMECFC 200
           QFYSFLHEMERVRTSMECFC
Sbjct: 180 QFYSFLHEMERVRTSMECFC 199


>gi|21361661 COMM domain containing 4 [Homo sapiens]
          Length = 199

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 7/194 (3%)

Query: 6   CTEDPVPEAVGGDMQQLNQLGAQQFSAL-TEVLFHFLTEPKEVERFLAQLSEFATTNQIS 64
           C +   P+ V  ++  L ++ + +   L ++VL   L +  + E+ L    +     +  
Sbjct: 6   CGDLDCPDWVLAEISTLAKMSSVKLRLLCSQVLKELLGQGIDYEKIL----KLTADAKFE 61

Query: 65  LGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTLARWA 124
            G +++ V  L  + + A K S+  + + ++   LGL +E A      +++    L +  
Sbjct: 62  SGDVKATVAVLSFILSSAAKHSVDGESLSSELQQLGLPKEHAASLCRCYEEKQSPLQKHL 121

Query: 125 IGQTLMINQLIDMEWKFGVTSGSSELEKVGS--IFLQLKLVVKKGNQTENVYIELTLPQF 182
              +L +N+L  + W+   T  SS L+ V    + L+L++    G   + V + L+  +F
Sbjct: 122 RVCSLRMNRLAGVGWRVDYTLSSSLLQSVEEPMVHLRLEVAAAPGTPAQPVAMSLSADKF 181

Query: 183 YSFLHEMERVRTSM 196
              L E+++ +T M
Sbjct: 182 QVLLAELKQAQTLM 195


>gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]
          Length = 85

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 132 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQFYSFLHEME 190
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF +F  + +
Sbjct: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFK 76

Query: 191 RVRTSME 197
            +   +E
Sbjct: 77  EIAAVIE 83


>gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]
          Length = 98

 Score = 33.1 bits (74), Expect = 0.16
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 132 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQF 182
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF
Sbjct: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQF 68


>gi|239755822 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 612

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 21/117 (17%)

Query: 14  AVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGSLRSIVK 73
           AV GD+    QLG  +   LT+   H L         L  L       Q+  G L   + 
Sbjct: 109 AVSGDLHVQGQLGVHELLVLTQQPGHVL---------LGLLQGLLQLGQLVPGILEGQLP 159

Query: 74  SLLLVPNGALK------------KSLTAKQVQADFITLGLSEEKATYFSEKWKQNAP 118
           +LL + NG L+            K + +     DFI +   E      SE  +Q AP
Sbjct: 160 TLLGIRNGVLQIGALQIERRRHHKLILSSGTLVDFILIPGGERDGKCLSEDEQQAAP 216


>gi|239750319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 612

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 21/117 (17%)

Query: 14  AVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGSLRSIVK 73
           AV GD+    QLG  +   LT+   H L         L  L       Q+  G L   + 
Sbjct: 109 AVSGDLHVQGQLGVHELLVLTQQPGHVL---------LGLLQGLLQLGQLVPGILEGQLP 159

Query: 74  SLLLVPNGALK------------KSLTAKQVQADFITLGLSEEKATYFSEKWKQNAP 118
           +LL + NG L+            K + +     DFI +   E      SE  +Q AP
Sbjct: 160 TLLGIRNGVLQIGALQIERRRHHKLILSSGTLVDFILIPGGERDGKCLSEDEQQAAP 216


>gi|239744623 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 612

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 21/117 (17%)

Query: 14  AVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGSLRSIVK 73
           AV GD+    QLG  +   LT+   H L         L  L       Q+  G L   + 
Sbjct: 109 AVSGDLHVQGQLGVHELLVLTQQPGHVL---------LGLLQGLLQLGQLVPGILEGQLP 159

Query: 74  SLLLVPNGALK------------KSLTAKQVQADFITLGLSEEKATYFSEKWKQNAP 118
           +LL + NG L+            K + +     DFI +   E      SE  +Q AP
Sbjct: 160 TLLGIRNGVLQIGALQIERRRHHKLILSSGTLVDFILIPGGERDGKCLSEDEQQAAP 216


>gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]
          Length = 198

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 22/155 (14%)

Query: 25  LGAQQFSALTEVLFHFLTEPKEVERFLAQLSEFATTNQISLGSLRSIVKSLLLVPNGALK 84
           L A+ F+AL  +L       K+V R L Q  E  +++ + L  L  +  S L V     +
Sbjct: 4   LTAEHFAALQSLL---KASSKDVVRQLCQ--ESFSSSALGLKKLLDVTCSSLSVTQEEAE 58

Query: 85  KSLTAKQVQADFIT---LGLSEEKATYFSEKWKQNAPTL---------ARW---AIGQTL 129
           + L A       +    L  +E     F E + QN   L         + W   A    +
Sbjct: 59  ELLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQI 118

Query: 130 MINQLIDMEWKFGVTSGSSELEK--VGSIFLQLKL 162
            + +L+D++W+  + + S  + +  V +  LQ+K+
Sbjct: 119 SLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKI 153


>gi|169208214 PREDICTED: similar to COMM domain containing 4 [Homo
           sapiens]
          Length = 422

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 22/102 (21%), Positives = 48/102 (47%), Gaps = 5/102 (4%)

Query: 6   CTEDPVPEAVGGDMQQLNQLGAQQFSAL-TEVLFHFLTEPKEVERFLAQLSEFATTNQIS 64
           C +   P+ V  ++  L ++ + +   L ++VL   L +  + ++ L    +     +  
Sbjct: 51  CGDLDCPDRVLAEISTLAKMSSVKLQLLCSQVLKELLGQGIDYKKIL----KLTADAKFE 106

Query: 65  LGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKA 106
            G +++ V  L  + +GA K S+  K + ++   LGL +E A
Sbjct: 107 SGDVKATVAVLSFILSGAAKHSVDGKSLASELQQLGLPKEHA 148


>gi|239735575 otoancorin isoform 3 [Homo sapiens]
          Length = 1060

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 12  PEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPK-----EVERFLAQLSEFATTNQISLG 66
           PEAV G +  LNQ+     S +  +   +L   K      V +  A L+  +T    S+ 
Sbjct: 328 PEAVHGAISTLNQVSGWAKSQVIILSAKYLAHEKVLSFYNVSQMGALLAGVSTQAFCSMK 387

Query: 67  S------LRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSE 111
                  LRS V   +   + A ++ + +K VQA+    G+ E +  +F E
Sbjct: 388 RKDISQVLRSAVSQYVSDLSPAQQQGILSKMVQAEDTAPGIVEIQGAFFKE 438


>gi|24638452 otoancorin isoform 2 [Homo sapiens]
          Length = 815

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 12  PEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPK-----EVERFLAQLSEFATTNQISLG 66
           PEAV G +  LNQ+     S +  +   +L   K      V +  A L+  +T    S+ 
Sbjct: 83  PEAVHGAISTLNQVSGWAKSQVIILSAKYLAHEKVLSFYNVSQMGALLAGVSTQAFCSMK 142

Query: 67  S------LRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSE 111
                  LRS V   +   + A ++ + +K VQA+    G+ E +  +F E
Sbjct: 143 RKDISQVLRSAVSQYVSDLSPAQQQGILSKMVQAEDTAPGIVEIQGAFFKE 193


>gi|77404409 otoancorin isoform 1 [Homo sapiens]
          Length = 1139

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 12  PEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPK-----EVERFLAQLSEFATTNQISLG 66
           PEAV G +  LNQ+     S +  +   +L   K      V +  A L+  +T    S+ 
Sbjct: 407 PEAVHGAISTLNQVSGWAKSQVIILSAKYLAHEKVLSFYNVSQMGALLAGVSTQAFCSMK 466

Query: 67  S------LRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSE 111
                  LRS V   +   + A ++ + +K VQA+    G+ E +  +F E
Sbjct: 467 RKDISQVLRSAVSQYVSDLSPAQQQGILSKMVQAEDTAPGIVEIQGAFFKE 517


>gi|33342278 TraB domain containing [Homo sapiens]
          Length = 376

 Score = 27.7 bits (60), Expect = 6.8
 Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 29/149 (19%)

Query: 9   DPVPEAVGGDMQQLNQLGAQQFSALTEVLFHFLTEPKEVERFLAQLSE-------FATTN 61
           +PVP  + GD Q L+ + A  F+ L E+      +   + R + QL            T 
Sbjct: 24  EPVPRVLSGDPQNLSDVDA--FNLLLEMKLKRRRQRPNLPRTVTQLVAEDGSRVYVVGTA 81

Query: 62  QISLGSLRSIVKSLLLVPNGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTLA 121
             S  S R +VK              T ++VQ D + + L + + +      K +  TL 
Sbjct: 82  HFSDDSKRDVVK--------------TIREVQPDVVVVELCQYRVSML----KMDESTLL 123

Query: 122 RWAIGQTLMINQLIDMEWKFGVTSGSSEL 150
           R A  Q L + +L     + G+ SG  ++
Sbjct: 124 REA--QELSLEKLQQAVRQNGLMSGLMQM 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,546,012
Number of Sequences: 37866
Number of extensions: 237808
Number of successful extensions: 597
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 592
Number of HSP's gapped (non-prelim): 14
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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