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Search of human proteins with 110224465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110224465 phosphatidylinositol glycan, class B [Homo
sapiens]
(554 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110224465 phosphatidylinositol glycan, class B [Homo sapiens] 1160 0.0
gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens] 80 6e-15
gi|118026921 asparagine-linked glycosylation 9 protein isoform a... 67 3e-11
gi|118026933 asparagine-linked glycosylation 9 protein isoform b... 67 3e-11
gi|30581137 phosphatidylinositol glycan anchor biosynthesis, cla... 62 1e-09
gi|118026935 asparagine-linked glycosylation 9 protein isoform d... 44 4e-04
gi|118026937 asparagine-linked glycosylation 9 protein isoform c... 44 4e-04
gi|49533617 sterol O-acyltransferase 1 [Homo sapiens] 30 4.4
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 30 5.8
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 30 5.8
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 30 5.8
>gi|110224465 phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 1160 bits (3001), Expect = 0.0
Identities = 554/554 (100%), Positives = 554/554 (100%)
Query: 1 MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGEN 60
MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGEN
Sbjct: 1 MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGEN 60
Query: 61 IYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLI 120
IYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLI
Sbjct: 61 IYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLI 120
Query: 121 FASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLC 180
FASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLC
Sbjct: 121 FASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLC 180
Query: 181 SWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWT 240
SWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWT
Sbjct: 181 SWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWT 240
Query: 241 PLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWG 300
PLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWG
Sbjct: 241 PLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWG 300
Query: 301 TFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEF 360
TFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEF
Sbjct: 301 TFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEF 360
Query: 361 RFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQK 420
RFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQK
Sbjct: 361 RFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQK 420
Query: 421 VCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNP 480
VCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNP
Sbjct: 421 VCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNP 480
Query: 481 LNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVY 540
LNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVY
Sbjct: 481 LNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVY 540
Query: 541 ERKLKGKFNMKMKF 554
ERKLKGKFNMKMKF
Sbjct: 541 ERKLKGKFNMKMKF 554
>gi|13129114 alpha-1,6-mannosyltransferase ALG12 [Homo sapiens]
Length = 488
Score = 79.7 bits (195), Expect = 6e-15
Identities = 98/377 (25%), Positives = 160/377 (42%), Gaps = 58/377 (15%)
Query: 49 SARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDE------YWQSLEVSHHMVFNYG 102
S+ RR LLG + + + T+ L I V+ SF +WQ LE H+ F G
Sbjct: 6 SSGRRPLLLG--LLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFP-G 62
Query: 103 YLTWEWTERLRSYTYPLIFA-----SIYKILHL-LGKDSVQLLIWIPRLAQALLSAVADV 156
+ R++ P++ A ++Y + L + K QL++ + +L
Sbjct: 63 VVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIV------RGVLGLGVIF 109
Query: 157 RLYSLMKQLENQEVARWVFFCQLCSWFTW---------YCCTRTLTNTMETVLTIIALFY 207
L++L K++ F + + F W + CTRTL N + + ++AL
Sbjct: 110 GLWTLQKEVRRH------FGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAA 163
Query: 208 YPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHFLPVG 265
+ ++ L A A I+ + L+ LL RK+ ++ L H +P G
Sbjct: 164 WLRH-----EWARFIWLSAFAIIVFRVELCLFLGLLLL-LALGNRKVSVVRALRHAVPAG 217
Query: 266 FVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLP 325
+ L L++ +D F+ Q T + L +N + N + +G+ P WYF P LG L
Sbjct: 218 ILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLL 277
Query: 326 FFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVF----CGYSL-TH 380
F G L +R V L + +YS+L HKE RFI P + C Y L +
Sbjct: 278 FIPLG--LVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNY 335
Query: 381 LKTWKKPALSFLFLSNL 397
K+W A S L + +L
Sbjct: 336 KKSWLYKAGSLLVIGHL 352
>gi|118026921 asparagine-linked glycosylation 9 protein isoform a
[Homo sapiens]
Length = 618
Score = 67.4 bits (163), Expect = 3e-11
Identities = 68/309 (22%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 85 DEYWQSLEVSHHMVFNYGYLTWEWTER--LRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142
DE + E +H++++ G+ TWE++ +RSY Y L+ A + + + L+ +
Sbjct: 82 DETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYF 141
Query: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202
R A +S + ++ Y + + V+R + + S + + L ++ T+
Sbjct: 142 LRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTL 201
Query: 203 IALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFL 262
IA+ + ++ + S+ + A A + P + L P+ F + R H L
Sbjct: 202 IAMTGWYMDKT----SIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFF-HWSL 256
Query: 263 PVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGT-FYGSHPWHWYFSQGFP---- 317
+ L ++ID ++G+ + N + +NV G YG+ PW++Y GF
Sbjct: 257 MALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNV 316
Query: 318 -------VILGTHLPFFI----HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPV 366
V+ T L ++ H L + L +W +++ + HKE RF++PV
Sbjct: 317 AFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW-FIIFFIQPHKEERFLFPV 375
Query: 367 LPFCMVFCG 375
P + CG
Sbjct: 376 YPL-ICLCG 383
>gi|118026933 asparagine-linked glycosylation 9 protein isoform b
[Homo sapiens]
Length = 611
Score = 67.4 bits (163), Expect = 3e-11
Identities = 68/309 (22%), Positives = 133/309 (43%), Gaps = 25/309 (8%)
Query: 85 DEYWQSLEVSHHMVFNYGYLTWEWTER--LRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142
DE + E +H++++ G+ TWE++ +RSY Y L+ A + + + L+ +
Sbjct: 82 DETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYF 141
Query: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202
R A +S + ++ Y + + V+R + + S + + L ++ T+
Sbjct: 142 LRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTL 201
Query: 203 IALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFL 262
IA+ + ++ + S+ + A A + P + L P+ F + R H L
Sbjct: 202 IAMTGWYMDKT----SIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFF-HWSL 256
Query: 263 PVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGT-FYGSHPWHWYFSQGFP---- 317
+ L ++ID ++G+ + N + +NV G YG+ PW++Y GF
Sbjct: 257 MALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNV 316
Query: 318 -------VILGTHLPFFI----HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPV 366
V+ T L ++ H L + L +W +++ + HKE RF++PV
Sbjct: 317 AFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW-FIIFFIQPHKEERFLFPV 375
Query: 367 LPFCMVFCG 375
P + CG
Sbjct: 376 YPL-ICLCG 383
>gi|30581137 phosphatidylinositol glycan anchor biosynthesis, class
Z [Homo sapiens]
Length = 579
Score = 62.4 bits (150), Expect = 1e-09
Identities = 115/455 (25%), Positives = 175/455 (38%), Gaps = 86/455 (18%)
Query: 70 LRILNCFLVQTSFV-PDEYWQSLEVSHHMVFNY-GYLTWEW--TERLRSYTYPLIFA-SI 124
LR+L C L QT +V PDE++QS EV + WE+ + RS +PL+ + S
Sbjct: 44 LRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGST 103
Query: 125 YKILHLL-------GKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFC 177
+ +L L G S L+ PRL LS D +Y L + RW
Sbjct: 104 FWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGAD---RWNALA 160
Query: 178 QLC-SWFTWYCCTRTLTNTMETVLTIIALFYY------------PLEGSKSMNSVKYSSL 224
L S+ T TRT +NT+E +L L P G + S +
Sbjct: 161 LLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPR-WRSWLLGGI 219
Query: 225 VALAFIIRPT----AVI---LW-TPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMID 276
VA F RPT AV+ LW T + + L+L LP +T ++ + D
Sbjct: 220 VAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVL---LPGAALTAAVFVATD 276
Query: 277 RIFFGQ------WTLVQFNFLKFNVLQNWGTFYGSHPWHWYFS-QGFPVI---------- 319
+F L NFL +N+ +G+H + + GF +
Sbjct: 277 SWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQA 336
Query: 320 --------------LGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYP 365
+G +P+ Y +LL + LL S SH+E RF+ P
Sbjct: 337 AWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALL--SAFSHQEARFLIP 394
Query: 366 VLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNN 425
+L ++ C T WK + F N AL G +HQ G + + ++++V +
Sbjct: 395 LLVPLVLLCS-PQTQPVPWKGTVVLF----NALGALLFGCLHQGGLVPGLEYLEQVVH-- 447
Query: 426 PNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCP 460
A + P H T ++H + P P L P
Sbjct: 448 -----APVLPSTPTHYTLLFTHTYMP-PRHLLHLP 476
>gi|118026935 asparagine-linked glycosylation 9 protein isoform d
[Homo sapiens]
Length = 440
Score = 43.9 bits (102), Expect = 4e-04
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 19/174 (10%)
Query: 218 SVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDR 277
S+ + A A + P + L P+ F + R H L + L ++ID
Sbjct: 42 SIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFF-HWSLMALILFLVPVVVIDS 100
Query: 278 IFFGQWTLVQFNFLKFNVLQNWGT-FYGSHPWHWYFSQGFP-----------VILGTHLP 325
++G+ + N + +NV G YG+ PW++Y GF V+ T L
Sbjct: 101 YYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLM 160
Query: 326 FFI----HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCG 375
++ H L + L +W +++ + HKE RF++PV P + CG
Sbjct: 161 EYLLQRFHVQNLGHPYWLTLAPMYIW-FIIFFIQPHKEERFLFPVYPL-ICLCG 212
>gi|118026937 asparagine-linked glycosylation 9 protein isoform c
[Homo sapiens]
Length = 447
Score = 43.9 bits (102), Expect = 4e-04
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 19/174 (10%)
Query: 218 SVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDR 277
S+ + A A + P + L P+ F + R H L + L ++ID
Sbjct: 42 SIAVLGVAAGAILGWPFSAALGLPIAFDLLVMKHRWKSFF-HWSLMALILFLVPVVVIDS 100
Query: 278 IFFGQWTLVQFNFLKFNVLQNWGT-FYGSHPWHWYFSQGFP-----------VILGTHLP 325
++G+ + N + +NV G YG+ PW++Y GF V+ T L
Sbjct: 101 YYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLM 160
Query: 326 FFI----HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCG 375
++ H L + L +W +++ + HKE RF++PV P + CG
Sbjct: 161 EYLLQRFHVQNLGHPYWLTLAPMYIW-FIIFFIQPHKEERFLFPVYPL-ICLCG 212
>gi|49533617 sterol O-acyltransferase 1 [Homo sapiens]
Length = 550
Score = 30.4 bits (67), Expect = 4.4
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 45/182 (24%)
Query: 243 LFRHFCQEP---RKLDLILHHFLPVGFVTLSLSLMI----------------DRIFFGQW 283
LFR+ QEP R L L + + + G + L L+ DR+F+ W
Sbjct: 348 LFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDW 407
Query: 284 ---TLVQFNFLKFNVL-QNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYR 339
T + +NV+ +W +Y + W+FS+ F +
Sbjct: 408 WNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRF--------------------KSA 447
Query: 340 ILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHL--KTWKKPALSFLFLSNL 397
+L + +V+ F YPVL +F G + + + KKP + L ++L
Sbjct: 448 AMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSL 507
Query: 398 FL 399
FL
Sbjct: 508 FL 509
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 30.0 bits (66), Expect = 5.8
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 143 PRLAQALLSAVADVRL----YSLMKQLENQE----VARWVFFCQLCSWFTWYCCTR 190
PR QALLSA + L Y + + L NQE + RW + W TW C+R
Sbjct: 9 PRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSR 64
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 30.0 bits (66), Expect = 5.8
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 143 PRLAQALLSAVADVRL----YSLMKQLENQE----VARWVFFCQLCSWFTWYCCTR 190
PR QALLSA + L Y + + L NQE + RW + W TW C+R
Sbjct: 9 PRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSR 64
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 30.0 bits (66), Expect = 5.8
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 8/56 (14%)
Query: 143 PRLAQALLSAVADVRL----YSLMKQLENQE----VARWVFFCQLCSWFTWYCCTR 190
PR QALLSA + L Y + + L NQE + RW + W TW C+R
Sbjct: 9 PRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSR 64
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,161,504
Number of Sequences: 37866
Number of extensions: 922352
Number of successful extensions: 2305
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2290
Number of HSP's gapped (non-prelim): 14
length of query: 554
length of database: 18,247,518
effective HSP length: 107
effective length of query: 447
effective length of database: 14,195,856
effective search space: 6345547632
effective search space used: 6345547632
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.