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Search of human proteins with 148539558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148539558 dystrophin related protein 2 [Homo sapiens]
(957 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148539558 dystrophin related protein 2 [Homo sapiens] 1927 0.0
gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] 1006 0.0
gi|5032309 dystrophin Dp140b isoform [Homo sapiens] 997 0.0
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 996 0.0
gi|5032295 dystrophin Dp116 isoform [Homo sapiens] 996 0.0
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 996 0.0
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 996 0.0
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 996 0.0
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 996 0.0
gi|5032293 dystrophin Dp140 isoform [Homo sapiens] 996 0.0
gi|5032285 dystrophin Dp427l isoform [Homo sapiens] 996 0.0
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 996 0.0
gi|110611228 utrophin [Homo sapiens] 884 0.0
gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] 801 0.0
gi|5032307 dystrophin Dp140c isoform [Homo sapiens] 794 0.0
gi|5032303 dystrophin Dp71ab isoform [Homo sapiens] 707 0.0
gi|5032301 dystrophin Dp71a isoform [Homo sapiens] 706 0.0
gi|5032299 dystrophin Dp71b isoform [Homo sapiens] 698 0.0
gi|5032297 dystrophin Dp71 isoform [Homo sapiens] 697 0.0
gi|5032305 dystrophin Dp40 isoform [Homo sapiens] 491 e-138
gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] 186 9e-47
gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] 183 8e-46
gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens] 179 1e-44
gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens] 178 2e-44
gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens] 177 5e-44
gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens] 177 5e-44
gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens] 177 5e-44
gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] 170 5e-42
gi|157364926 dystrotelin [Homo sapiens] 155 2e-37
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] 152 1e-36
>gi|148539558 dystrophin related protein 2 [Homo sapiens]
Length = 957
Score = 1927 bits (4992), Expect = 0.0
Identities = 957/957 (100%), Positives = 957/957 (100%)
Query: 1 MQPMVMQGCPYTLPRCHDWQAADQFHHSSSLRSTCPHPQVRAAVTSPAPPQDGAGVPCLS 60
MQPMVMQGCPYTLPRCHDWQAADQFHHSSSLRSTCPHPQVRAAVTSPAPPQDGAGVPCLS
Sbjct: 1 MQPMVMQGCPYTLPRCHDWQAADQFHHSSSLRSTCPHPQVRAAVTSPAPPQDGAGVPCLS 60
Query: 61 LKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQ 120
LKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQ
Sbjct: 61 LKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQ 120
Query: 121 KDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEE 180
KDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEE
Sbjct: 121 KDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEE 180
Query: 181 PHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAM 240
PHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAM
Sbjct: 181 PHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAM 240
Query: 241 EELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLA 300
EELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLA
Sbjct: 241 EELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLA 300
Query: 301 ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWER 360
ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWER
Sbjct: 301 ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWER 360
Query: 361 AISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDL 420
AISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDL
Sbjct: 361 AISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDL 420
Query: 421 VTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLL 480
VTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLL
Sbjct: 421 VTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLL 480
Query: 481 NVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQ 540
NVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQ
Sbjct: 481 NVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQ 540
Query: 541 VPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTI 600
VPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTI
Sbjct: 541 VPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTI 600
Query: 601 AEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPT 660
AEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPT
Sbjct: 601 AEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPT 660
Query: 661 TSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSR 720
TSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSR
Sbjct: 661 TSSENMRDFATTLKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSR 720
Query: 721 IEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATE 780
IEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATE
Sbjct: 721 IEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATE 780
Query: 781 SKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEAR 840
SKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEAR
Sbjct: 781 SKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEAR 840
Query: 841 ILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEG 900
ILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEG
Sbjct: 841 ILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEG 900
Query: 901 SHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS 957
SHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS
Sbjct: 901 SHPREKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS 957
>gi|5032311 dystrophin Dp140ab isoform [Homo sapiens]
Length = 1230
Score = 1006 bits (2602), Expect = 0.0
Identities = 495/883 (56%), Positives = 653/883 (73%), Gaps = 14/883 (1%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSF 738
+K YF+KHP+ GYLPVQ+VLE D ETPASSP H DTHSRIEH+ASRLAEME+ N S+
Sbjct: 922 TKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 981
Query: 739 FNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVATESKGELQKILAH 791
NDS+SP++SID++ L++H SP++ +P Q S+ +E +GEL++ILA
Sbjct: 982 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLESEERGELERILAD 1039
Query: 792 LEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRL 849
LE+ENR LQ E RLK QHE + PS + + R+ EL+AEA++LRQHK RL
Sbjct: 1040 LEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRL 1099
Query: 850 ETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP---REK 906
E RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q+S+ S P R
Sbjct: 1100 EARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVV 1159
Query: 907 GQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDV 949
G T D+ +D+ S QD S LE++ME+L ++FPS R +V
Sbjct: 1160 GSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV 1202
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
>gi|5032309 dystrophin Dp140b isoform [Homo sapiens]
Length = 1243
Score = 997 bits (2578), Expect = 0.0
Identities = 495/896 (55%), Positives = 653/896 (72%), Gaps = 27/896 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 922 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 981
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 1039
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 1040 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 1099
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 1100 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 1159
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDV 949
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R +V
Sbjct: 1160 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV 1215
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 2774 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 2833
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 2834 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 2893
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 2894 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 2953
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 2954 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 3013
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 3014 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 3073
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 3074 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 3133
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 3134 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 3193
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 3194 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 3253
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 3254 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 3313
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 3314 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 3373
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 3374 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 3433
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 3434 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 3491
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 3492 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 3551
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 3552 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 3611
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 3612 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 3663
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 2473 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 2532
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 2533 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 2573
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 2574 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2632
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 2633 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 2681
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/238 (21%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 106 KLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLES 165
+ Q L+E++ WL ++ L AQ + DV +V+ + TH +M ++ + + ++L+
Sbjct: 335 RYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQL 394
Query: 166 AQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRH 225
+ E EE V +Q + + WE L +++ +
Sbjct: 395 GSKLIGTGKLSEDEETE------------------VQEQMNLLNSRWECLRVASMEKQSN 436
Query: 226 IERTLEQLLEIQGAMEELSTTLSQAE--GVRATWEPIGDLFIDSLPEHIQAIKLFKEEFS 283
+ R L L + ++EL+ L++ E + EP+G ++ L +Q K+ +E+
Sbjct: 437 LHRVLMDLQNQK--LKELNDWLTKTEERTRKMEEEPLGP-DLEDLKRQVQQHKVLQEDLE 493
Query: 284 PMKDGVKLVNDLAHQLAISDV----HLSMENSQALEQINVRWKQLQASVSERLKQLQD 337
++ V+ VN L H + + D H + + L+ + RW + +R LQD
Sbjct: 494 --QEQVR-VNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQD 548
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 48/257 (18%)
Query: 93 LRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVA----LVQQEKETHAAF 148
L+A LE GKL Q+++ L K + L LVQ+ +++ A
Sbjct: 598 LKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQI 657
Query: 149 MEEVKSRGPYIY--SVLESA------QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRF 200
+ V + P + +V+E+ + L +H EEL P + K
Sbjct: 658 SQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKK-------------- 703
Query: 201 VWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPI 260
+Q TV SE+ ++L + H I R+ + ++ + + EG
Sbjct: 704 --RQITVDSEIRKRLDVDITELHSWITRS-------EAVLQSPEFAIFRKEGN------- 747
Query: 261 GDLFIDSLPEHIQAIKLFK-EEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINV 319
L E + AI+ K E+F ++D + L Q+ V+ QA EQ+N
Sbjct: 748 ----FSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNAD-SIKQASEQLNS 802
Query: 320 RWKQLQASVSERLKQLQ 336
RW + +SERL L+
Sbjct: 803 RWIEFCQLLSERLNWLE 819
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 2179 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 2236
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 2237 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 2286
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 2287 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 2334
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 2335 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 2389
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 2390 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 2445
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 2446 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 2484
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/256 (16%), Positives = 106/256 (41%), Gaps = 22/256 (8%)
Query: 83 WNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEK 142
W ++ + +LE + K+Q +Q + W+++ D L + P GD +++++
Sbjct: 1021 WKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQL 1080
Query: 143 ETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVW 202
+ + ++++ P + SV E Q ++ E +E K+ + +
Sbjct: 1081 KQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQ----------- 1129
Query: 203 KQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGD 262
W+ + + + ++ LE+ + +Q + E+ ++QAE
Sbjct: 1130 ---------WDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAE-EEYLERDFEY 1179
Query: 263 LFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN-SQALEQINVRW 321
D L + ++ +K KEE + VKL+ + + + ++ E + LE + +
Sbjct: 1180 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNY 1239
Query: 322 KQLQASVSERLKQLQD 337
+ L ++ + K L++
Sbjct: 1240 QWLCTRLNGKCKTLEE 1255
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 1539 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 1598
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 1599 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 1647
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 1648 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1698
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 39/267 (14%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEE-LSAQLPLQGDVAL 137
+N W+ + ++ + + L+ + + LQ L E+ +W++Q +EE L + L
Sbjct: 1126 LNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDEL 1185
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ +E A EE + + + + ES + ++Q P +++ K+
Sbjct: 1186 QKAVEEMKRA-KEEAQQKEAKVKLLTESVNSVIAQAP--------PVAQEALKKELETLT 1236
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLL----EIQGAMEELSTTLSQAEGV 253
+ + W L +L +C +TLE++ E+ +E+ + L++ E
Sbjct: 1237 TNYQW--------LCTRLNGKC--------KTLEEVWACWHELLSYLEKANKWLNEVEFK 1280
Query: 254 RATWE--PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENS 311
T E P G I + + ++ + E D + LA L V + N
Sbjct: 1281 LKTTENIPGGAEEISEVLDSLENLMRHSE------DNPNQIRILAQTLTDGGVMDELINE 1334
Query: 312 QALEQINVRWKQLQASVSERLKQLQDA 338
+ LE N RW++L R K L+ +
Sbjct: 1335 E-LETFNSRWRELHEEAVRRQKLLEQS 1360
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 2049 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 2108
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 2109 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 2157
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 2158 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 2200
>gi|5032295 dystrophin Dp116 isoform [Homo sapiens]
Length = 956
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 292
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 293 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 352
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 353 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 412
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 413 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 472
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 473 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 532
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 533 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 592
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 593 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 652
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 653 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 712
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 713 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 770
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 771 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 830
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 831 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 890
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 891 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 942
>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
Length = 2341
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 1438 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 1497
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 1498 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 1557
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 1558 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 1617
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 1618 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 1677
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 1678 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 1737
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 1738 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 1797
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 1798 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 1857
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 1858 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 1917
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 1918 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 1977
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 1978 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 2037
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 2038 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 2097
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 2098 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 2155
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 2156 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 2215
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 2216 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 2275
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 2276 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 2327
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 1137 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 1196
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 1197 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 1237
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 1238 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1296
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 1297 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 1345
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 843 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 900
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 901 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 950
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 951 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 998
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 999 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 1053
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 1054 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 1109
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 1110 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 1148
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 203 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 262
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 263 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 311
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 312 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 362
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 713 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 772
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 773 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 821
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 822 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 864
>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
Length = 2344
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 1441 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 1500
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 1501 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 1560
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 1561 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 1620
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 1621 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 1680
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 1681 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 1740
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 1741 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 1800
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 1801 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 1860
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 1861 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 1920
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 1921 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 1980
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 1981 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 2040
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 2041 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 2100
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 2101 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 2158
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 2159 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 2218
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 2219 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 2278
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 2279 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 2330
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 1140 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 1199
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 1200 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 1240
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 1241 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1299
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 1300 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 1348
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 846 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 903
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 904 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 953
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 954 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 1001
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 1002 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 1056
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 1057 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 1112
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 1113 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 1151
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 206 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 265
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 266 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 314
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 315 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 365
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 716 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 775
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 776 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 824
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 825 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 867
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 2659 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 2718
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 2719 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 2778
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 2779 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 2838
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 2839 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 2898
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 2899 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 2958
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 2959 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 3018
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 3019 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 3078
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 3079 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 3138
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 3139 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 3198
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 3199 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 3258
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 3259 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 3318
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 3319 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 3376
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 3377 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 3436
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 3437 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 3496
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 3497 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 3548
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 2358 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 2417
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 2418 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 2458
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 2459 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 2566
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/238 (21%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 106 KLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLES 165
+ Q L+E++ WL ++ L AQ + DV +V+ + TH +M ++ + + ++L+
Sbjct: 220 RYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQL 279
Query: 166 AQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRH 225
+ E EE V +Q + + WE L +++ +
Sbjct: 280 GSKLIGTGKLSEDEETE------------------VQEQMNLLNSRWECLRVASMEKQSN 321
Query: 226 IERTLEQLLEIQGAMEELSTTLSQAE--GVRATWEPIGDLFIDSLPEHIQAIKLFKEEFS 283
+ R L L + ++EL+ L++ E + EP+G ++ L +Q K+ +E+
Sbjct: 322 LHRVLMDLQNQK--LKELNDWLTKTEERTRKMEEEPLGP-DLEDLKRQVQQHKVLQEDLE 378
Query: 284 PMKDGVKLVNDLAHQLAISDV----HLSMENSQALEQINVRWKQLQASVSERLKQLQD 337
++ V+ VN L H + + D H + + L+ + RW + +R LQD
Sbjct: 379 --QEQVR-VNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQD 433
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 48/257 (18%)
Query: 93 LRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVA----LVQQEKETHAAF 148
L+A LE GKL Q+++ L K + L LVQ+ +++ A
Sbjct: 483 LKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQI 542
Query: 149 MEEVKSRGPYIY--SVLESA------QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRF 200
+ V + P + +V+E+ + L +H EEL P + K
Sbjct: 543 SQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKK-------------- 588
Query: 201 VWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPI 260
+Q TV SE+ ++L + H I R+ + ++ + + EG
Sbjct: 589 --RQITVDSEIRKRLDVDITELHSWITRS-------EAVLQSPEFAIFRKEGN------- 632
Query: 261 GDLFIDSLPEHIQAIKLFK-EEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINV 319
L E + AI+ K E+F ++D + L Q+ V+ QA EQ+N
Sbjct: 633 ----FSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNAD-SIKQASEQLNS 687
Query: 320 RWKQLQASVSERLKQLQ 336
RW + +SERL L+
Sbjct: 688 RWIEFCQLLSERLNWLE 704
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 2064 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 2121
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 2122 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 2171
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 2172 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 2219
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 2220 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 2274
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 2275 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 2330
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 2331 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 2369
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/256 (16%), Positives = 106/256 (41%), Gaps = 22/256 (8%)
Query: 83 WNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEK 142
W ++ + +LE + K+Q +Q + W+++ D L + P GD +++++
Sbjct: 906 WKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQL 965
Query: 143 ETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVW 202
+ + ++++ P + SV E Q ++ E +E K+ + +
Sbjct: 966 KQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQ----------- 1014
Query: 203 KQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGD 262
W+ + + + ++ LE+ + +Q + E+ ++QAE
Sbjct: 1015 ---------WDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAE-EEYLERDFEY 1064
Query: 263 LFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN-SQALEQINVRW 321
D L + ++ +K KEE + VKL+ + + + ++ E + LE + +
Sbjct: 1065 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNY 1124
Query: 322 KQLQASVSERLKQLQD 337
+ L ++ + K L++
Sbjct: 1125 QWLCTRLNGKCKTLEE 1140
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 1424 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 1483
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 1484 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 1532
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 1533 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1583
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 39/267 (14%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEE-LSAQLPLQGDVAL 137
+N W+ + ++ + + L+ + + LQ L E+ +W++Q +EE L + L
Sbjct: 1011 LNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDEL 1070
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ +E A EE + + + + ES + ++Q P +++ K+
Sbjct: 1071 QKAVEEMKRA-KEEAQQKEAKVKLLTESVNSVIAQAP--------PVAQEALKKELETLT 1121
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLL----EIQGAMEELSTTLSQAEGV 253
+ + W L +L +C +TLE++ E+ +E+ + L++ E
Sbjct: 1122 TNYQW--------LCTRLNGKC--------KTLEEVWACWHELLSYLEKANKWLNEVEFK 1165
Query: 254 RATWE--PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENS 311
T E P G I + + ++ + E D + LA L V + N
Sbjct: 1166 LKTTENIPGGAEEISEVLDSLENLMRHSE------DNPNQIRILAQTLTDGGVMDELINE 1219
Query: 312 QALEQINVRWKQLQASVSERLKQLQDA 338
+ LE N RW++L R K L+ +
Sbjct: 1220 E-LETFNSRWRELHEEAVRRQKLLEQS 1245
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 1934 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 1993
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 1994 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 2042
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 2043 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 2085
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 2778 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 2837
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 2838 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 2897
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 2898 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 2957
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 2958 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 3017
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 3018 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 3077
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 3078 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 3137
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 3138 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 3197
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 3198 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 3257
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 3258 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 3317
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 3318 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 3377
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 3378 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 3437
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 3438 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 3495
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 3496 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 3555
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 3556 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 3615
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 3616 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 3667
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 2477 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 2536
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 2537 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 2577
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 2578 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2636
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 2637 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 2685
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/238 (21%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 106 KLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLES 165
+ Q L+E++ WL ++ L AQ + DV +V+ + TH +M ++ + + ++L+
Sbjct: 339 RYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQL 398
Query: 166 AQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRH 225
+ E EE V +Q + + WE L +++ +
Sbjct: 399 GSKLIGTGKLSEDEETE------------------VQEQMNLLNSRWECLRVASMEKQSN 440
Query: 226 IERTLEQLLEIQGAMEELSTTLSQAE--GVRATWEPIGDLFIDSLPEHIQAIKLFKEEFS 283
+ R L L + ++EL+ L++ E + EP+G ++ L +Q K+ +E+
Sbjct: 441 LHRVLMDLQNQK--LKELNDWLTKTEERTRKMEEEPLGP-DLEDLKRQVQQHKVLQEDLE 497
Query: 284 PMKDGVKLVNDLAHQLAISDV----HLSMENSQALEQINVRWKQLQASVSERLKQLQD 337
++ V+ VN L H + + D H + + L+ + RW + +R LQD
Sbjct: 498 --QEQVR-VNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQD 552
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 48/257 (18%)
Query: 93 LRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVA----LVQQEKETHAAF 148
L+A LE GKL Q+++ L K + L LVQ+ +++ A
Sbjct: 602 LKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQI 661
Query: 149 MEEVKSRGPYIY--SVLESA------QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRF 200
+ V + P + +V+E+ + L +H EEL P + K
Sbjct: 662 SQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKK-------------- 707
Query: 201 VWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPI 260
+Q TV SE+ ++L + H I R+ + ++ + + EG
Sbjct: 708 --RQITVDSEIRKRLDVDITELHSWITRS-------EAVLQSPEFAIFRKEGN------- 751
Query: 261 GDLFIDSLPEHIQAIKLFK-EEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINV 319
L E + AI+ K E+F ++D + L Q+ V+ QA EQ+N
Sbjct: 752 ----FSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNAD-SIKQASEQLNS 806
Query: 320 RWKQLQASVSERLKQLQ 336
RW + +SERL L+
Sbjct: 807 RWIEFCQLLSERLNWLE 823
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 2183 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 2240
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 2241 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 2290
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 2291 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 2338
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 2339 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 2393
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 2394 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 2449
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 2450 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 2488
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/256 (16%), Positives = 106/256 (41%), Gaps = 22/256 (8%)
Query: 83 WNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEK 142
W ++ + +LE + K+Q +Q + W+++ D L + P GD +++++
Sbjct: 1025 WKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQL 1084
Query: 143 ETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVW 202
+ + ++++ P + SV E Q ++ E +E K+ + +
Sbjct: 1085 KQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQ----------- 1133
Query: 203 KQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGD 262
W+ + + + ++ LE+ + +Q + E+ ++QAE
Sbjct: 1134 ---------WDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAE-EEYLERDFEY 1183
Query: 263 LFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN-SQALEQINVRW 321
D L + ++ +K KEE + VKL+ + + + ++ E + LE + +
Sbjct: 1184 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNY 1243
Query: 322 KQLQASVSERLKQLQD 337
+ L ++ + K L++
Sbjct: 1244 QWLCTRLNGKCKTLEE 1259
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 1543 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 1602
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 1603 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 1651
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 1652 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1702
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 39/267 (14%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEE-LSAQLPLQGDVAL 137
+N W+ + ++ + + L+ + + LQ L E+ +W++Q +EE L + L
Sbjct: 1130 LNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDEL 1189
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ +E A EE + + + + ES + ++Q P +++ K+
Sbjct: 1190 QKAVEEMKRA-KEEAQQKEAKVKLLTESVNSVIAQAP--------PVAQEALKKELETLT 1240
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLL----EIQGAMEELSTTLSQAEGV 253
+ + W L +L +C +TLE++ E+ +E+ + L++ E
Sbjct: 1241 TNYQW--------LCTRLNGKC--------KTLEEVWACWHELLSYLEKANKWLNEVEFK 1284
Query: 254 RATWE--PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENS 311
T E P G I + + ++ + E D + LA L V + N
Sbjct: 1285 LKTTENIPGGAEEISEVLDSLENLMRHSE------DNPNQIRILAQTLTDGGVMDELINE 1338
Query: 312 QALEQINVRWKQLQASVSERLKQLQDA 338
+ LE N RW++L R K L+ +
Sbjct: 1339 E-LETFNSRWRELHEEAVRRQKLLEQS 1364
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 2053 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 2112
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 2113 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 2161
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 2162 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 2204
>gi|5032293 dystrophin Dp140 isoform [Homo sapiens]
Length = 1225
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 922 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 981
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 1039
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 1040 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 1099
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 1100 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 1159
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 1160 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 1211
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
Length = 3562
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 2659 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 2718
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 2719 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 2778
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 2779 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 2838
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 2839 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 2898
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 2899 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 2958
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 2959 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 3018
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 3019 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 3078
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 3079 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 3138
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 3139 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 3198
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 3199 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 3258
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 3259 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 3318
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 3319 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 3376
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 3377 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 3436
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 3437 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 3496
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 3497 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 3548
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 2358 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 2417
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 2418 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 2458
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 2459 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 2566
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/238 (21%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 106 KLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLES 165
+ Q L+E++ WL ++ L AQ + DV +V+ + TH +M ++ + + ++L+
Sbjct: 220 RYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQL 279
Query: 166 AQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRH 225
+ E EE V +Q + + WE L +++ +
Sbjct: 280 GSKLIGTGKLSEDEETE------------------VQEQMNLLNSRWECLRVASMEKQSN 321
Query: 226 IERTLEQLLEIQGAMEELSTTLSQAE--GVRATWEPIGDLFIDSLPEHIQAIKLFKEEFS 283
+ R L L + ++EL+ L++ E + EP+G ++ L +Q K+ +E+
Sbjct: 322 LHRVLMDLQNQK--LKELNDWLTKTEERTRKMEEEPLGP-DLEDLKRQVQQHKVLQEDLE 378
Query: 284 PMKDGVKLVNDLAHQLAISDV----HLSMENSQALEQINVRWKQLQASVSERLKQLQD 337
++ V+ VN L H + + D H + + L+ + RW + +R LQD
Sbjct: 379 --QEQVR-VNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQD 433
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 48/257 (18%)
Query: 93 LRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVA----LVQQEKETHAAF 148
L+A LE GKL Q+++ L K + L LVQ+ +++ A
Sbjct: 483 LKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQI 542
Query: 149 MEEVKSRGPYIY--SVLESA------QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRF 200
+ V + P + +V+E+ + L +H EEL P + K
Sbjct: 543 SQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKK-------------- 588
Query: 201 VWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPI 260
+Q TV SE+ ++L + H I R+ + ++ + + EG
Sbjct: 589 --RQITVDSEIRKRLDVDITELHSWITRS-------EAVLQSPEFAIFRKEGN------- 632
Query: 261 GDLFIDSLPEHIQAIKLFK-EEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINV 319
L E + AI+ K E+F ++D + L Q+ V+ QA EQ+N
Sbjct: 633 ----FSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNAD-SIKQASEQLNS 687
Query: 320 RWKQLQASVSERLKQLQ 336
RW + +SERL L+
Sbjct: 688 RWIEFCQLLSERLNWLE 704
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 2064 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 2121
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 2122 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 2171
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 2172 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 2219
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 2220 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 2274
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 2275 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 2330
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 2331 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 2369
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/256 (16%), Positives = 106/256 (41%), Gaps = 22/256 (8%)
Query: 83 WNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEK 142
W ++ + +LE + K+Q +Q + W+++ D L + P GD +++++
Sbjct: 906 WKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQL 965
Query: 143 ETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVW 202
+ + ++++ P + SV E Q ++ E +E K+ + +
Sbjct: 966 KQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQ----------- 1014
Query: 203 KQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGD 262
W+ + + + ++ LE+ + +Q + E+ ++QAE
Sbjct: 1015 ---------WDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAE-EEYLERDFEY 1064
Query: 263 LFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN-SQALEQINVRW 321
D L + ++ +K KEE + VKL+ + + + ++ E + LE + +
Sbjct: 1065 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNY 1124
Query: 322 KQLQASVSERLKQLQD 337
+ L ++ + K L++
Sbjct: 1125 QWLCTRLNGKCKTLEE 1140
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 1424 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 1483
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 1484 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 1532
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 1533 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1583
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 39/267 (14%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEE-LSAQLPLQGDVAL 137
+N W+ + ++ + + L+ + + LQ L E+ +W++Q +EE L + L
Sbjct: 1011 LNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDEL 1070
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ +E A EE + + + + ES + ++Q P +++ K+
Sbjct: 1071 QKAVEEMKRA-KEEAQQKEAKVKLLTESVNSVIAQAP--------PVAQEALKKELETLT 1121
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLL----EIQGAMEELSTTLSQAEGV 253
+ + W L +L +C +TLE++ E+ +E+ + L++ E
Sbjct: 1122 TNYQW--------LCTRLNGKC--------KTLEEVWACWHELLSYLEKANKWLNEVEFK 1165
Query: 254 RATWE--PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENS 311
T E P G I + + ++ + E D + LA L V + N
Sbjct: 1166 LKTTENIPGGAEEISEVLDSLENLMRHSE------DNPNQIRILAQTLTDGGVMDELINE 1219
Query: 312 QALEQINVRWKQLQASVSERLKQLQDA 338
+ LE N RW++L R K L+ +
Sbjct: 1220 E-LETFNSRWRELHEEAVRRQKLLEQS 1245
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 1934 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 1993
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 1994 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 2042
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 2043 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 2085
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 996 bits (2574), Expect = 0.0
Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 2782 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 2841
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 2842 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 2901
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 2902 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 2961
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 2962 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 3021
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 3022 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 3081
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 3082 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 3141
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 3142 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 3201
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 3202 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 3261
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 3262 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 3321
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 3322 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 3381
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725
+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A
Sbjct: 3382 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 3441
Query: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778
SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+
Sbjct: 3442 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 3499
Query: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836
+E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+
Sbjct: 3500 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 3559
Query: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896
AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q
Sbjct: 3560 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 3619
Query: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 3620 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 3671
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 2481 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 2540
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 2541 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 2581
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 2582 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2640
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 2641 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 2689
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/238 (21%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 106 KLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLES 165
+ Q L+E++ WL ++ L AQ + DV +V+ + TH +M ++ + + ++L+
Sbjct: 343 RYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQL 402
Query: 166 AQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRH 225
+ E EE V +Q + + WE L +++ +
Sbjct: 403 GSKLIGTGKLSEDEETE------------------VQEQMNLLNSRWECLRVASMEKQSN 444
Query: 226 IERTLEQLLEIQGAMEELSTTLSQAE--GVRATWEPIGDLFIDSLPEHIQAIKLFKEEFS 283
+ R L L + ++EL+ L++ E + EP+G ++ L +Q K+ +E+
Sbjct: 445 LHRVLMDLQNQK--LKELNDWLTKTEERTRKMEEEPLGP-DLEDLKRQVQQHKVLQEDLE 501
Query: 284 PMKDGVKLVNDLAHQLAISDV----HLSMENSQALEQINVRWKQLQASVSERLKQLQD 337
++ V+ VN L H + + D H + + L+ + RW + +R LQD
Sbjct: 502 --QEQVR-VNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQD 556
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 48/257 (18%)
Query: 93 LRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVA----LVQQEKETHAAF 148
L+A LE GKL Q+++ L K + L LVQ+ +++ A
Sbjct: 606 LKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQI 665
Query: 149 MEEVKSRGPYIY--SVLESA------QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRF 200
+ V + P + +V+E+ + L +H EEL P + K
Sbjct: 666 SQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKK-------------- 711
Query: 201 VWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPI 260
+Q TV SE+ ++L + H I R+ + ++ + + EG
Sbjct: 712 --RQITVDSEIRKRLDVDITELHSWITRS-------EAVLQSPEFAIFRKEGN------- 755
Query: 261 GDLFIDSLPEHIQAIKLFK-EEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINV 319
L E + AI+ K E+F ++D + L Q+ V+ QA EQ+N
Sbjct: 756 ----FSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNAD-SIKQASEQLNS 810
Query: 320 RWKQLQASVSERLKQLQ 336
RW + +SERL L+
Sbjct: 811 RWIEFCQLLSERLNWLE 827
Score = 43.5 bits (101), Expect = 0.001
Identities = 72/339 (21%), Positives = 132/339 (38%), Gaps = 51/339 (15%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQ-GDVA 136
++NL W E+ K+ + + RLE + + Q L E + WL + D A +PL+ G
Sbjct: 2187 SLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADN--IASIPLEPGKEQ 2244
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
++++ E +EE+ R + + E+ L P E+ E+K
Sbjct: 2245 QLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENK---------- 2294
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
KQ + W K++ ++ IE ++ L +++ +E+L L+
Sbjct: 2295 -----LKQTNLQ---WIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHL----LL 2342
Query: 257 W-EPI-GDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN---- 310
W PI L I + P + + E + V+ ++ HL E
Sbjct: 2343 WLSPIRNQLEIYNQPNQEGPFDVQETEIA-----VQAKQPDVEEILSKGQHLYKEKPATQ 2397
Query: 311 --SQALEQINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQ---------VPWE 359
+ LE ++ WK +V+ L++L+ D PG +S Q V E
Sbjct: 2398 PVKRKLEDLSSEWK----AVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKE 2453
Query: 360 RAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNI 398
AIS ++P + + + TEL L+ L+ +
Sbjct: 2454 TAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQV 2492
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/256 (16%), Positives = 106/256 (41%), Gaps = 22/256 (8%)
Query: 83 WNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEK 142
W ++ + +LE + K+Q +Q + W+++ D L + P GD +++++
Sbjct: 1029 WKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQL 1088
Query: 143 ETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVW 202
+ + ++++ P + SV E Q ++ E +E K+ + +
Sbjct: 1089 KQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQ----------- 1137
Query: 203 KQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGD 262
W+ + + + ++ LE+ + +Q + E+ ++QAE
Sbjct: 1138 ---------WDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAE-EEYLERDFEY 1187
Query: 263 LFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMEN-SQALEQINVRW 321
D L + ++ +K KEE + VKL+ + + + ++ E + LE + +
Sbjct: 1188 KTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNY 1247
Query: 322 KQLQASVSERLKQLQD 337
+ L ++ + K L++
Sbjct: 1248 QWLCTRLNGKCKTLEE 1263
Score = 37.0 bits (84), Expect = 0.088
Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 78 AMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVAL 137
A+ L +NE+ K + +LE S K++ + + +WL+ D EL+ + ++G +
Sbjct: 1547 ALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSN 1606
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ E A +E++ + ++ S+ E +A + K+T + ++ +L
Sbjct: 1607 LDSEVAWGKATQKEIEKQKVHLKSITEVGEAL----------KTVLGKKETLVEDKL-SL 1655
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAE 251
W T +E W L ++ +H+E + + I + + T L ++E
Sbjct: 1656 LNSNWIAVTSRAEEWLNL---LLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1706
Score = 35.4 bits (80), Expect = 0.26
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 39/267 (14%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEE-LSAQLPLQGDVAL 137
+N W+ + ++ + + L+ + + LQ L E+ +W++Q +EE L + L
Sbjct: 1134 LNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDEL 1193
Query: 138 VQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNL 197
+ +E A EE + + + + ES + ++Q P +++ K+
Sbjct: 1194 QKAVEEMKRA-KEEAQQKEAKVKLLTESVNSVIAQAP--------PVAQEALKKELETLT 1244
Query: 198 SRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLL----EIQGAMEELSTTLSQAEGV 253
+ + W L +L +C +TLE++ E+ +E+ + L++ E
Sbjct: 1245 TNYQW--------LCTRLNGKC--------KTLEEVWACWHELLSYLEKANKWLNEVEFK 1288
Query: 254 RATWE--PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENS 311
T E P G I + + ++ + E D + LA L V + N
Sbjct: 1289 LKTTENIPGGAEEISEVLDSLENLMRHSE------DNPNQIRILAQTLTDGGVMDELINE 1342
Query: 312 QALEQINVRWKQLQASVSERLKQLQDA 338
+ LE N RW++L R K L+ +
Sbjct: 1343 E-LETFNSRWRELHEEAVRRQKLLEQS 1368
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/163 (20%), Positives = 73/163 (44%), Gaps = 21/163 (12%)
Query: 185 SKDTSPKQRIQNLSRFVWKQATVASEL-WEKLTARCVDQHRHIERTLEQLLEIQGAMEEL 243
SK T+ Q + R ++A + WEK+ D+ +R++E+ ++
Sbjct: 2057 SKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIF 2116
Query: 244 STTLSQAEG-VRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAIS 302
+ L++AE +R T +PE+ + K +K ++DG+ + L +
Sbjct: 2117 NQWLTEAEQFLRKT----------QIPENWEHAK-YKWYLKELQDGIGQRQTVVRTLNAT 2165
Query: 303 DVHLSMENSQA--------LEQINVRWKQLQASVSERLKQLQD 337
+ ++S+ L +N+RW+++ +S+R K+L++
Sbjct: 2166 GEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEE 2208
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 884 bits (2284), Expect = 0.0
Identities = 458/890 (51%), Positives = 618/890 (69%), Gaps = 29/890 (3%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN WN++K KS ++RA LEA ++ +L + L+E+I WL+ KDEEL Q+P+ GDV +
Sbjct: 2536 MNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPAL 2595
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHS--ESK-DTSPKQRIQ 195
Q + + A E+K + + + ++ A+ FL+ P E EEP +SK + +P++R Q
Sbjct: 2596 QLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRNLQSKTELTPEERAQ 2655
Query: 196 NLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRA 255
+++ + KQ++ E WE L A + + +++ LE+L ++QGAM++L + +AE VR
Sbjct: 2656 KIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKEAESVRN 2715
Query: 256 TWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALE 315
W+P+GDL IDSL +HI+ I F+EE +P+ VK VNDL+ QL+ D+H S++ S+ L+
Sbjct: 2716 GWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSPLDLHPSLKMSRQLD 2775
Query: 316 QINVRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQA 375
+N+RWK LQ SV +RLKQLQ+AHRDFGP SQHFLS+SVQ+PW+R+IS NKVPYYINHQ
Sbjct: 2776 DLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVPYYINHQT 2835
Query: 376 QTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDL 435
QTTCWDHPKMTEL+Q+LADLNN++FSAYRTA+K+RR+QKAL LDL+ L+T EIF +H L
Sbjct: 2836 QTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNEIFKQHKL 2895
Query: 436 QASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALS 495
++ ++ V +VI+CLT Y+ LE+ LVNVPLCVDM LNWLLNV+D+GR+GK+R S
Sbjct: 2896 NQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQS 2955
Query: 496 FKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSN 555
K G+ L ++EK +YLF +VA CDQR LG+LLH+AIQ+PRQLGEVAAFGGSN
Sbjct: 2956 LKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQIPRQLGEVAAFGGSN 3015
Query: 556 VEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQ 615
+EPSVRSCF+ + KP I +F++W++LEPQSMVWL VLHRV AE KHQ KC+IC++
Sbjct: 3016 IEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKHQAKCNICKE 3075
Query: 616 CPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKN 675
CPI GFRYRSLK FN D+CQ+CF +GR +KG+KLHYP++EY PTTS E++RDF LKN
Sbjct: 3076 CPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKVLKN 3135
Query: 676 KFRSKHYFSKHPQRGYLPVQSVLEADYSETPAS-SPMWP------------HADTHSRIE 722
KFRSK YF+KHP+ GYLPVQ+VLE D ETP + MWP H DTHSRIE
Sbjct: 3136 KFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEHYDPSQSPQLFHDDTHSRIE 3195
Query: 723 HFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLL-RHSSPITDREPAFGQQAPC----SV 777
+A+RLA+ME N SF DS S S++++ L+ ++ + P Q+P SV
Sbjct: 3196 QYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQTLGGESPVSQPQSPAQILKSV 3255
Query: 778 ATESKGELQKILAHLEDENRILQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNE--EL 835
E +GEL++I+A LE+E R LQ E +LK QH P + + + H +E EL
Sbjct: 3256 EREERGELERIIADLEEEQRNLQVEYEQLKDQHLRRG-LPVGSPPESIISPHHTSEDSEL 3314
Query: 836 LAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSP 895
+AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP ESD S G S +SP
Sbjct: 3315 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP--ESD-SRINGVSPWASP 3371
Query: 896 QQSEGSHPREKGQTTPD--TEAADDVGSKSQDVSLCLEDIMEKLRHAFPS 943
Q S S+ + + P A +D+ + D S L ++ME++ FPS
Sbjct: 3372 QHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPS 3421
Score = 61.6 bits (148), Expect = 3e-09
Identities = 55/239 (23%), Positives = 106/239 (44%), Gaps = 36/239 (15%)
Query: 108 QLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQ 167
Q+ L+E++ WL ++ Q + DV V+ + TH AFM E+ + + SVL++
Sbjct: 315 QIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGN 374
Query: 168 AFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIE 227
++Q + EE + +Q T+ + WE L +D+ +
Sbjct: 375 QLITQGTLSDEEEFE------------------IQEQMTLLNARWEALRVESMDRQSRLH 416
Query: 228 RTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKD 287
L +L + Q +++LS L+ E E I + L + +++++ EE ++
Sbjct: 417 DVLMELQKKQ--LQQLSAWLTLTE------ERIQKMETCPLDDDVKSLQKLLEEHKSLQS 468
Query: 288 GVKL----VNDLAHQLAISDVHLSMENSQA-----LEQINVRWKQLQASVSERLKQLQD 337
++ VN L H + I D + S E++ A L+++ RW + ER +LQ+
Sbjct: 469 DLEAEQVKVNSLTHMVVIVDEN-SGESATAILEDQLQKLGERWTAVCRWTEERWNRLQE 526
Score = 37.7 bits (86), Expect = 0.052
Identities = 52/264 (19%), Positives = 108/264 (40%), Gaps = 33/264 (12%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQ--LPLQGDVA 136
+N W ++ +S + ++RL K QL Q++ WL+ +E + PL DV
Sbjct: 397 LNARWEALRVESMDRQSRLHDVLMELQKKQL--QQLSAWLTLTEERIQKMETCPLDDDVK 454
Query: 137 LVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQN 196
+Q+ E H + ++++ + S+ H ++E ES + ++Q
Sbjct: 455 SLQKLLEEHKSLQSDLEAEQVKVNSLT---------HMVVIVDENSGESATAILEDQLQK 505
Query: 197 LSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRAT 256
L E W +L + I ++LLE Q ++ T +A T
Sbjct: 506 LGERWTAVCRWTEERWNRL--------QEINILWQELLEEQCLLKAWLTEKEEALNKVQT 557
Query: 257 WEPIGDLFIDS--LPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQAL 314
F D L ++ + + KE+ + + ++++ DV ++NS+A
Sbjct: 558 SN-----FKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQ-----DVGQLLDNSKAS 607
Query: 315 EQINVRWKQLQASVSERLKQLQDA 338
++IN ++L +++L+D+
Sbjct: 608 KKINSDSEELTQRWDSLVQRLEDS 631
Score = 36.6 bits (83), Expect = 0.12
Identities = 32/152 (21%), Positives = 74/152 (48%), Gaps = 21/152 (13%)
Query: 194 IQNLSR----FVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQ 249
+Q LS+ F+ ++ ++ W+ + A D+ ++ +Q+++ + ++E+ L++
Sbjct: 2043 VQKLSQADGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTK 2102
Query: 250 AEGV---RATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHL 306
AE R+T E L E++Q ++ +E + +K +N ++ +SD L
Sbjct: 2103 AEHAMQKRSTTE---------LGENLQELRDLTQEMEVHAEKLKWLNRTELEM-LSDKSL 2152
Query: 307 SMEN----SQALEQINVRWKQLQASVSERLKQ 334
S+ S++L +N+ W ++ V LK+
Sbjct: 2153 SLPERDKISESLRTVNMTWNKICREVPTTLKE 2184
Score = 32.0 bits (71), Expect = 2.8
Identities = 26/127 (20%), Positives = 56/127 (44%), Gaps = 5/127 (3%)
Query: 212 WEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRA-TWEPIGDLFIDSLPE 270
W+++ D+ +R +E+ + + +L+ +++AE + T P G L ++
Sbjct: 1957 WDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARI 2016
Query: 271 HIQAIKLFKEEFSPMKDGVKLVND-LAHQLAISDVHLSMENSQALEQINVRWKQLQASVS 329
H Q +++ P + D + +L+ +D E L +N RW + A V
Sbjct: 2017 HQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEK---LAGLNQRWDAIVAEVK 2073
Query: 330 ERLKQLQ 336
+R +L+
Sbjct: 2074 DRQPRLK 2080
Score = 31.6 bits (70), Expect = 3.7
Identities = 36/160 (22%), Positives = 61/160 (38%), Gaps = 7/160 (4%)
Query: 204 QATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWEPIGDL 263
Q+T E E A ++ L+ Q A+EE+ T L AE + I D
Sbjct: 285 QSTAPEEEHESPRAETPSTVTEVDMDLDSY---QIALEEVLTWLLSAEDTFQEQDDISD- 340
Query: 264 FIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQ---INVR 320
++ + + + F E + + V V +QL E + EQ +N R
Sbjct: 341 DVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNAR 400
Query: 321 WKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWER 360
W+ L+ +R +L D + LS+ + + ER
Sbjct: 401 WEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTEER 440
Score = 30.4 bits (67), Expect = 8.3
Identities = 50/241 (20%), Positives = 92/241 (38%), Gaps = 18/241 (7%)
Query: 107 LQLPLQEIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESA 166
L + E+ DWL D+ L + + GDV + + +++ R P + V A
Sbjct: 2231 LDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQLDYVFTLA 2290
Query: 167 QAFLSQHPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHR-- 224
Q ++ ++ +E + Q +Q + + + L D HR
Sbjct: 2291 QNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQ---WDDHREE 2347
Query: 225 --HIERTLEQLLEI--QGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKE 280
+ R E L I Q + L+ +S + + P GD + + +Q KL +E
Sbjct: 2348 TEELMRKYEARLYILQQARRDPLTKQISDNQILLQELGP-GDGIVMAFDNVLQ--KLLEE 2404
Query: 281 EFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQINVRWKQLQAS---VSERLKQLQD 337
S D + V + L S ++L + + W+ +QAS + LK +Q+
Sbjct: 2405 YGS---DDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQE 2461
Query: 338 A 338
A
Sbjct: 2462 A 2462
>gi|5032313 dystrophin Dp140bc isoform [Homo sapiens]
Length = 1133
Score = 801 bits (2070), Expect = 0.0
Identities = 412/855 (48%), Positives = 566/855 (66%), Gaps = 49/855 (5%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSF 738
+K YF+KHP+ GYLPVQ+VLE D ET + AE +
Sbjct: 922 TKRYFAKHPRMGYLPVQTVLEGDNMET--------------------NLQAEYDRLKQQH 961
Query: 739 FNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGELQKILAHLEDENRI 798
+ LSP S E + +SP + R+ +A + + KG L+ + LED N+
Sbjct: 962 EHKGLSPLPSPPE----MMPTSPQSPRDAELIAEA--KLLRQHKGRLEARMQILEDHNKQ 1015
Query: 799 LQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILED 858
L+ +L RL+ Q E +A + +G+T + + + L++ S ++++
Sbjct: 1016 LESQLHRLR-QLLEQPQAEAKVNGTT----------VSSPSTSLQRSDSSQPMLLRVVGS 1064
Query: 859 HNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPREKGQTTPDT-EAAD 917
+ E LL PP ++ + L +Q S P +G AD
Sbjct: 1065 QTSDSMGE-----EDLLSPPQDT------STGLEEVMEQLNNSFPSSRGHNVGSLFHMAD 1113
Query: 918 DVGSKSQDVSLCLED 932
D+G + + + D
Sbjct: 1114 DLGRAMESLVSVMTD 1128
Score = 129 bits (323), Expect = 2e-29
Identities = 76/156 (48%), Positives = 100/156 (64%), Gaps = 5/156 (3%)
Query: 799 LQGELRRLKWQHEEA--AEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQIL 856
LQ E RLK QHE + PS + + R+ EL+AEA++LRQHK RLE RMQIL
Sbjct: 950 LQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQIL 1009
Query: 857 EDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP---REKGQTTPDT 913
EDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q+S+ S P R G T D+
Sbjct: 1010 EDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDS 1069
Query: 914 EAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDV 949
+D+ S QD S LE++ME+L ++FPS R +V
Sbjct: 1070 MGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV 1105
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
>gi|5032307 dystrophin Dp140c isoform [Homo sapiens]
Length = 1105
Score = 794 bits (2051), Expect = 0.0
Identities = 407/840 (48%), Positives = 560/840 (66%), Gaps = 58/840 (6%)
Query: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138
MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V
Sbjct: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381
Query: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198
Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++
Sbjct: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441
Query: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258
R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+
Sbjct: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501
Query: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318
P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N
Sbjct: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561
Query: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378
RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT
Sbjct: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621
Query: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438
CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ +
Sbjct: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681
Query: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498
+ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT
Sbjct: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741
Query: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558
GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP
Sbjct: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801
Query: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618
SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI
Sbjct: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861
Query: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678
GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR
Sbjct: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921
Query: 679 SKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSF 738
+K YF+KHP+ GYLPVQ+ L+A+Y RL +
Sbjct: 922 TKRYFAKHPRMGYLPVQN-LQAEY-----------------------DRLKQQHE----- 952
Query: 739 FNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGELQKILAHLEDENRI 798
+ LSP S E + +SP + R+ +A + + KG L+ + LED N+
Sbjct: 953 -HKGLSPLPSPPE----MMPTSPQSPRDAELIAEA--KLLRQHKGRLEARMQILEDHNKQ 1005
Query: 799 LQGELRRLKWQHEEAAEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILED 858
L+ +L RL+ Q E +A + +G+T + + + L++ S ++++
Sbjct: 1006 LESQLHRLR-QLLEQPQAEAKVNGTT----------VSSPSTSLQRSDSSQPMLLRVVGS 1054
Query: 859 HNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPREKGQTTPDTEAADD 918
+ E LL PP ++ + L +Q S P +G+ TP +D
Sbjct: 1055 QTSDSMGE-----EDLLSPPQDT------STGLEEVMEQLNNSFPSSRGRNTPGKPMRED 1103
Score = 127 bits (319), Expect = 5e-29
Identities = 75/152 (49%), Positives = 98/152 (64%), Gaps = 5/152 (3%)
Query: 799 LQGELRRLKWQHEEA--AEAPSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQIL 856
LQ E RLK QHE + PS + + R+ EL+AEA++LRQHK RLE RMQIL
Sbjct: 940 LQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQIL 999
Query: 857 EDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP---REKGQTTPDT 913
EDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q+S+ S P R G T D+
Sbjct: 1000 EDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDS 1059
Query: 914 EAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
+D+ S QD S LE++ME+L ++FPS R
Sbjct: 1060 MGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 1091
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172
E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++
Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80
Query: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232
+E + + T +RIQN W+++ ++ + + L+
Sbjct: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121
Query: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292
+ A EE L QA +W+ G +D++ + I K ++ + V +
Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180
Query: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340
NDLA +L VH+ EN IN W+ + VSER L++ HR
Sbjct: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229
>gi|5032303 dystrophin Dp71ab isoform [Homo sapiens]
Length = 622
Score = 707 bits (1826), Expect = 0.0
Identities = 349/589 (59%), Positives = 452/589 (76%), Gaps = 14/589 (2%)
Query: 373 HQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNE 432
H+ QTTCWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++
Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67
Query: 433 HDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMR 492
H+L+ ++ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R
Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127
Query: 493 ALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFG 552
LSFKTGI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187
Query: 553 GSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSI 612
GSN+EPSVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+I
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247
Query: 613 CRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATT 672
C++CPI GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307
Query: 673 LKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEME 732
LKNKFR+K YF+KHP+ GYLPVQ+VLE D ETPASSP H DTHSRIEH+ASRLAEME
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEME 367
Query: 733 SQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVATESKGEL 785
+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+ +E +GEL
Sbjct: 368 NSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLESEERGEL 425
Query: 786 QKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELLAEARILR 843
++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+AEA++LR
Sbjct: 426 ERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLR 485
Query: 844 QHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP 903
QHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q+S+ S P
Sbjct: 486 QHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQP 545
Query: 904 ---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDV 949
R G T D+ +D+ S QD S LE++ME+L ++FPS R +V
Sbjct: 546 MLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNV 594
>gi|5032301 dystrophin Dp71a isoform [Homo sapiens]
Length = 604
Score = 706 bits (1822), Expect = 0.0
Identities = 348/585 (59%), Positives = 450/585 (76%), Gaps = 14/585 (2%)
Query: 373 HQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNE 432
H+ QTTCWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++
Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67
Query: 433 HDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMR 492
H+L+ ++ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R
Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127
Query: 493 ALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFG 552
LSFKTGI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187
Query: 553 GSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSI 612
GSN+EPSVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+I
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247
Query: 613 CRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATT 672
C++CPI GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307
Query: 673 LKNKFRSKHYFSKHPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEME 732
LKNKFR+K YF+KHP+ GYLPVQ+VLE D ETPASSP H DTHSRIEH+ASRLAEME
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQLSHDDTHSRIEHYASRLAEME 367
Query: 733 SQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVATESKGEL 785
+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+ +E +GEL
Sbjct: 368 NSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLESEERGEL 425
Query: 786 QKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELLAEARILR 843
++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+AEA++LR
Sbjct: 426 ERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLR 485
Query: 844 QHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHP 903
QHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q+S+ S P
Sbjct: 486 QHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQP 545
Query: 904 ---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 546 MLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 590
>gi|5032299 dystrophin Dp71b isoform [Homo sapiens]
Length = 635
Score = 698 bits (1802), Expect = 0.0
Identities = 349/602 (57%), Positives = 452/602 (75%), Gaps = 27/602 (4%)
Query: 373 HQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNE 432
H+ QTTCWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++
Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67
Query: 433 HDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMR 492
H+L+ ++ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R
Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127
Query: 493 ALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFG 552
LSFKTGI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187
Query: 553 GSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSI 612
GSN+EPSVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+I
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247
Query: 613 CRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATT 672
C++CPI GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307
Query: 673 LKNKFRSKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHS 719
LKNKFR+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHS
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367
Query: 720 RIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQ 772
RIEH+ASRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q
Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQ 425
Query: 773 APCSVATESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDH 830
S+ +E +GEL++ILA LE+ENR LQ E RLK QHE + PS + +
Sbjct: 426 ILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSP 485
Query: 831 RNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSS 890
R+ EL+AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS
Sbjct: 486 RDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSS 545
Query: 891 LASSPQQSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSS 947
++S Q+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 546 PSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGH 605
Query: 948 DV 949
+V
Sbjct: 606 NV 607
>gi|5032297 dystrophin Dp71 isoform [Homo sapiens]
Length = 617
Score = 697 bits (1798), Expect = 0.0
Identities = 348/598 (58%), Positives = 450/598 (75%), Gaps = 27/598 (4%)
Query: 373 HQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNE 432
H+ QTTCWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++
Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67
Query: 433 HDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMR 492
H+L+ ++ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R
Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127
Query: 493 ALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFG 552
LSFKTGI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187
Query: 553 GSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSI 612
GSN+EPSVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+I
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247
Query: 613 CRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATT 672
C++CPI GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307
Query: 673 LKNKFRSKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHS 719
LKNKFR+K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHS
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367
Query: 720 RIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQ 772
RIEH+ASRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q
Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQ 425
Query: 773 APCSVATESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDH 830
S+ +E +GEL++ILA LE+ENR LQ E RLK QHE + PS + +
Sbjct: 426 ILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSP 485
Query: 831 RNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSS 890
R+ EL+AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS
Sbjct: 486 RDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSS 545
Query: 891 LASSPQQSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945
++S Q+S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R
Sbjct: 546 PSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 603
>gi|5032305 dystrophin Dp40 isoform [Homo sapiens]
Length = 340
Score = 491 bits (1263), Expect = e-138
Identities = 222/333 (66%), Positives = 282/333 (84%)
Query: 373 HQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNE 432
H+ QTTCWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++
Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67
Query: 433 HDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMR 492
H+L+ ++ MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R
Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127
Query: 493 ALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFG 552
LSFKTGI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FG
Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187
Query: 553 GSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSI 612
GSN+EPSVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+I
Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247
Query: 613 CRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATT 672
C++CPI GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA
Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307
Query: 673 LKNKFRSKHYFSKHPQRGYLPVQSVLEADYSET 705
LKNKFR+K YF+KHP+ GYLPVQ+VLE D ET
Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 340
>gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens]
Length = 686
Score = 186 bits (472), Expect = 9e-47
Identities = 146/511 (28%), Positives = 250/511 (48%), Gaps = 43/511 (8%)
Query: 394 DLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEH--VMDVVEVIHCL 451
DL+ I+ S YRTA KLR VQK L LV + +E E+ L + ++V + L
Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85
Query: 452 TALYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVK 509
+ ++ +L + ++V + + LN+LL FD GK+ + K +A LCG ++
Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145
Query: 510 EKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTG 569
+KL+Y+FS +++S L E +++P + E +FG + E S RSCF +
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200
Query: 570 KPVIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLK 627
+ + + FL+ + +P Q +VWL +LHR+ E V H +CS C + GFRYR +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260
Query: 628 QFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHP 687
N +CQ CF G A + + + EY + + ++ + + + + S+ HP
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSRE--PLHP 318
Query: 688 QRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFNDS-LSPD 746
P + + A +T WP S + S + S F S L
Sbjct: 319 MFPDQPEKPLNLAHIVDT------WPPRPVTSMNDTLFSH--SVPSSGSPFITRSMLESS 370
Query: 747 DSIDED-----QYLLRHSSPITDREPAFGQQAP-CSVATESKGELQKILAHLEDENRILQ 800
+ +DE+ +Y R ++ + +P + AP S ++ + ++++A LE++NR +
Sbjct: 371 NRLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAELENKNREIL 430
Query: 801 GELRRLKWQHEEAAE-APSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILEDH 859
E++RL+ +HE+A++ P A +N LLAE R+LRQ K LE RM L++
Sbjct: 431 QEIQRLRLEHEQASQPTPEKA---------QQNPTLLAELRLLRQRKDELEQRMSALQES 481
Query: 860 NKQLESQLQRLRELLLQPPTESDGSGSAGSS 890
++L QL+ L +LL ++ G+GS SS
Sbjct: 482 RRELMVQLEGLMKLL-----KTQGAGSPRSS 507
>gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens]
Length = 513
Score = 183 bits (464), Expect = 8e-46
Identities = 141/495 (28%), Positives = 242/495 (48%), Gaps = 38/495 (7%)
Query: 394 DLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEH--VMDVVEVIHCL 451
DL+ I+ S YRTA KLR VQK L LV + +E E+ L + ++V + L
Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85
Query: 452 TALYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVK 509
+ ++ +L + ++V + + LN+LL FD GK+ + K +A LCG ++
Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145
Query: 510 EKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTG 569
+KL+Y+FS +++S L E +++P + E +FG + E S RSCF +
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200
Query: 570 KPVIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLK 627
+ + + FL+ + +P Q +VWL +LHR+ E V H +CS C + GFRYR +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260
Query: 628 QFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHP 687
N +CQ CF G A + + + EY + + ++ + + + + S+ HP
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSRE--PLHP 318
Query: 688 QRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFNDS-LSPD 746
P + + A +T WP S + S + S F S L
Sbjct: 319 MFPDQPEKPLNLAHIVDT------WPPRPVTSMNDTLFSH--SVPSSGSPFITRSMLESS 370
Query: 747 DSIDED-----QYLLRHSSPITDREPAFGQQAP-CSVATESKGELQKILAHLEDENRILQ 800
+ +DE+ +Y R ++ + +P + AP S ++ + ++++A LE++NR +
Sbjct: 371 NRLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAELENKNREIL 430
Query: 801 GELRRLKWQHEEAAE-APSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILEDH 859
E++RL+ +HE+A++ P A +N LLAE R+LRQ K LE RM L++
Sbjct: 431 QEIQRLRLEHEQASQPTPEKA---------QQNPTLLAELRLLRQRKDELEQRMSALQES 481
Query: 860 NKQLESQLQRLRELL 874
++L QL+ L +LL
Sbjct: 482 RRELMVQLEGLMKLL 496
>gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens]
Length = 560
Score = 179 bits (453), Expect = 1e-44
Identities = 147/536 (27%), Positives = 247/536 (46%), Gaps = 73/536 (13%)
Query: 398 IKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDV----VEVIHCLTA 453
I+ S YRTA KLR VQK L LV + +E F ++ L +H ++ +E + +++
Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETV--ISS 87
Query: 454 LYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEK 511
+Y +L + ++V + + LN+++ +DS GK+ S K +A +CG ++ +K
Sbjct: 88 IYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDK 147
Query: 512 LQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKP 571
L+Y+FSQ+++S L E +++P + E +FG + E SVR+CF +
Sbjct: 148 LRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCF---PQQR 202
Query: 572 VIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQF 629
I + FL+ + +P Q +VWL ++HR+ E V H +CS CR + GFRYR +
Sbjct: 203 KIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCH 262
Query: 630 NVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSK---- 685
N +CQ CF G A P ++ M++ ++ + H SK
Sbjct: 263 NYQLCQNCFWRGHAG-------------GPHSNQHQMKEHSSWKSPAKKLSHAISKSLGC 309
Query: 686 ----HPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFND 741
P P Q D + P+ DT + H +S +
Sbjct: 310 VPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDT--MVSHMSSGVPTPT-------KS 360
Query: 742 SLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVA--TESKGELQKILAHLEDENRIL 799
L +DE+ L+ + E + P ++ ++ + ++++A LE++NR +
Sbjct: 361 VLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREI 420
Query: 800 QGELRRLKWQHEEAAE-APSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILED 858
E++RL+ +HE+A++ P A +N LLAE R+LRQ K LE RM L++
Sbjct: 421 LQEIQRLRLEHEQASQPTPEKA---------QQNPTLLAELRLLRQRKDELEQRMSALQE 471
Query: 859 HNKQLESQLQRLRELLL--------QPPTESDG--------SGSAGSSLASSPQQS 898
++L QL+ L +LL PT G S SAGS+ PQ S
Sbjct: 472 SRRELMVQLEELMKLLKAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDS 527
>gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]
Length = 567
Score = 178 bits (451), Expect = 2e-44
Identities = 142/522 (27%), Positives = 244/522 (46%), Gaps = 59/522 (11%)
Query: 398 IKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDV----VEVIHCLTA 453
I+ S YRTA KLR VQK L LV + +E F ++ L +H ++ +E + +++
Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETV--ISS 87
Query: 454 LYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEK 511
+Y +L + ++V + + LN+++ +DS GK+ S K +A +CG ++ +K
Sbjct: 88 IYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDK 147
Query: 512 LQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKP 571
L+Y+FSQ+++S L E +++P + E +FG + E SVR+CF +
Sbjct: 148 LRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCF---PQQR 202
Query: 572 VIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQF 629
I + FL+ + +P Q +VWL ++HR+ E V H +CS CR + GFRYR +
Sbjct: 203 KIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCH 262
Query: 630 NVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSK---- 685
N +CQ CF G A P ++ M++ ++ + H SK
Sbjct: 263 NYQLCQNCFWRGHAG-------------GPHSNQHQMKEHSSWKSPAKKLSHAISKSLGC 309
Query: 686 ----HPQRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFND 741
P P Q D + P+ DT + H +S +
Sbjct: 310 VPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDT--MVSHMSSGVPTPT-------KS 360
Query: 742 SLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSVA--TESKGELQKILAHLEDENRIL 799
L +DE+ L+ + E + P ++ ++ + ++++A LE++NR +
Sbjct: 361 VLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREI 420
Query: 800 QGELRRLKWQHEEAAE-APSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILED 858
E++RL+ +HE+A++ P A +N LLAE R+LRQ K LE RM L++
Sbjct: 421 LQEIQRLRLEHEQASQPTPEKA---------QQNPTLLAELRLLRQRKDELEQRMSALQE 471
Query: 859 HNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEG 900
++L QL+ L +LL + E + A S +SP G
Sbjct: 472 SRRELMVQLEELMKLLKE--EEQKQAAQATGSPHTSPTHGGG 511
>gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens]
Length = 627
Score = 177 bits (448), Expect = 5e-44
Identities = 150/551 (27%), Positives = 254/551 (46%), Gaps = 87/551 (15%)
Query: 398 IKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDV----VEVIHCLTA 453
I+ S YRTA KLR VQK L LV + +E F ++ L +H ++ +E + +++
Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETV--ISS 87
Query: 454 LYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEK 511
+Y +L + ++V + + LN+++ +DS GK+ S K +A +CG ++ +K
Sbjct: 88 IYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDK 147
Query: 512 LQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKP 571
L+Y+FSQ+++S L E +++P + E +FG + E SVR+CF +
Sbjct: 148 LRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCF---PQQR 202
Query: 572 VIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQF 629
I + FL+ + +P Q +VWL ++HR+ E V H +CS CR + GFRYR +
Sbjct: 203 KIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCH 262
Query: 630 NVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSK---- 685
N +CQ CF G A P ++ M++ ++ + H SK
Sbjct: 263 NYQLCQNCFWRGHAG-------------GPHSNQHQMKEHSSWKSPAKKLSHAISKSLGC 309
Query: 686 ----HPQRGYLPVQSVLEADYSE-------TPASSPMWPH-------------------- 714
P P Q D + T + M H
Sbjct: 310 VPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPS 369
Query: 715 --ADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQ 772
AD H+ I + +RL Q+C+ DS S +DE+ L+ + E +
Sbjct: 370 HLADEHALIASYVARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAGNVTR 421
Query: 773 APCSVA--TESKGELQKILAHLEDENRILQGELRRLKWQHEEAAE-APSLADGSTEAATD 829
P ++ ++ + ++++A LE++NR + E++RL+ +HE+A++ P A
Sbjct: 422 PPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKA--------- 472
Query: 830 HRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGS 889
+N LLAE R+LRQ K LE RM L++ ++L QL+ L +LL + E + A
Sbjct: 473 QQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKE--EEQKQAAQATG 530
Query: 890 SLASSPQQSEG 900
S +SP G
Sbjct: 531 SPHTSPTHGGG 541
>gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]
Length = 597
Score = 177 bits (448), Expect = 5e-44
Identities = 150/551 (27%), Positives = 254/551 (46%), Gaps = 87/551 (15%)
Query: 398 IKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDV----VEVIHCLTA 453
I+ S YRTA KLR VQK L LV + +E F ++ L +H ++ +E + +++
Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETV--ISS 87
Query: 454 LYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEK 511
+Y +L + ++V + + LN+++ +DS GK+ S K +A +CG ++ +K
Sbjct: 88 IYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDK 147
Query: 512 LQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKP 571
L+Y+FSQ+++S L E +++P + E +FG + E SVR+CF +
Sbjct: 148 LRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCF---PQQR 202
Query: 572 VIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQF 629
I + FL+ + +P Q +VWL ++HR+ E V H +CS CR + GFRYR +
Sbjct: 203 KIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCH 262
Query: 630 NVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSK---- 685
N +CQ CF G A P ++ M++ ++ + H SK
Sbjct: 263 NYQLCQNCFWRGHAG-------------GPHSNQHQMKEHSSWKSPAKKLSHAISKSLGC 309
Query: 686 ----HPQRGYLPVQSVLEADYSE-------TPASSPMWPH-------------------- 714
P P Q D + T + M H
Sbjct: 310 VPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPS 369
Query: 715 --ADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQ 772
AD H+ I + +RL Q+C+ DS S +DE+ L+ + E +
Sbjct: 370 HLADEHALIASYVARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAGNVTR 421
Query: 773 APCSVA--TESKGELQKILAHLEDENRILQGELRRLKWQHEEAAE-APSLADGSTEAATD 829
P ++ ++ + ++++A LE++NR + E++RL+ +HE+A++ P A
Sbjct: 422 PPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKA--------- 472
Query: 830 HRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGS 889
+N LLAE R+LRQ K LE RM L++ ++L QL+ L +LL + E + A
Sbjct: 473 QQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKE--EEQKQAAQATG 530
Query: 890 SLASSPQQSEG 900
S +SP G
Sbjct: 531 SPHTSPTHGGG 541
>gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens]
Length = 609
Score = 177 bits (448), Expect = 5e-44
Identities = 150/551 (27%), Positives = 254/551 (46%), Gaps = 87/551 (15%)
Query: 398 IKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDV----VEVIHCLTA 453
I+ S YRTA KLR VQK L LV + +E F ++ L +H ++ +E + +++
Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETV--ISS 87
Query: 454 LYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEK 511
+Y +L + ++V + + LN+++ +DS GK+ S K +A +CG ++ +K
Sbjct: 88 IYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDK 147
Query: 512 LQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKP 571
L+Y+FSQ+++S L E +++P + E +FG + E SVR+CF +
Sbjct: 148 LRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCF---PQQR 202
Query: 572 VIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQF 629
I + FL+ + +P Q +VWL ++HR+ E V H +CS CR + GFRYR +
Sbjct: 203 KIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCH 262
Query: 630 NVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSK---- 685
N +CQ CF G A P ++ M++ ++ + H SK
Sbjct: 263 NYQLCQNCFWRGHAG-------------GPHSNQHQMKEHSSWKSPAKKLSHAISKSLGC 309
Query: 686 ----HPQRGYLPVQSVLEADYSE-------TPASSPMWPH-------------------- 714
P P Q D + T + M H
Sbjct: 310 VPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPS 369
Query: 715 --ADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQ 772
AD H+ I + +RL Q+C+ DS S +DE+ L+ + E +
Sbjct: 370 HLADEHALIASYVARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAGNVTR 421
Query: 773 APCSVA--TESKGELQKILAHLEDENRILQGELRRLKWQHEEAAE-APSLADGSTEAATD 829
P ++ ++ + ++++A LE++NR + E++RL+ +HE+A++ P A
Sbjct: 422 PPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKA--------- 472
Query: 830 HRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGS 889
+N LLAE R+LRQ K LE RM L++ ++L QL+ L +LL + E + A
Sbjct: 473 QQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKE--EEQKQAAQATG 530
Query: 890 SLASSPQQSEG 900
S +SP G
Sbjct: 531 SPHTSPTHGGG 541
>gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens]
Length = 567
Score = 170 bits (431), Expect = 5e-42
Identities = 147/539 (27%), Positives = 249/539 (46%), Gaps = 72/539 (13%)
Query: 394 DLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEH--VMDVVEVIHCL 451
DL+ I+ S YRTA KLR VQK L LV + +E E+ L + ++V + L
Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85
Query: 452 TALYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVK 509
+ ++ +L + ++V + + LN+LL FD GK+ + K +A LCG ++
Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145
Query: 510 EKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTG 569
+KL+Y+FS +++S L E +++P + E +FG + E S RSCF +
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200
Query: 570 KPVIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLK 627
+ + + FL+ + +P Q +VWL +LHR+ E V H +CS C + GFRYR +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260
Query: 628 QFNVDICQTCFLTGRASKGNKLHYPIMEY---YTPTTSSENMRDFATTLKNKFRSKH-YF 683
N +CQ CF G A + + + EY +P N + + + H F
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMF 320
Query: 684 SKHPQRGY--------LPVQSVLEADYSETPAS--SPMWPHAD--THSRIE--------- 722
P++ PV S+ + +S + S SP + S +E
Sbjct: 321 PDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEVEQNKLLARAA 380
Query: 723 -------------HFASRLAEMESQNCSFFN-------DSLSPDDSIDED-----QYLLR 757
+ A RLA+ + N L + +DE+ +Y R
Sbjct: 381 PAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEEHRLIARYAAR 440
Query: 758 HSSPITDREPAFGQQAP-CSVATESKGELQKILAHLEDENRILQGELRRLKWQHEEAAE- 815
++ + +P + AP S ++ + ++++A LE++NR + E++RL+ +HE+A++
Sbjct: 441 LAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQP 500
Query: 816 APSLADGSTEAATDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELL 874
P A +N LLAE R+LRQ K LE RM L++ ++L QL+ L +LL
Sbjct: 501 TPEKA---------QQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLL 550
>gi|157364926 dystrotelin [Homo sapiens]
Length = 578
Score = 155 bits (391), Expect = 2e-37
Identities = 95/289 (32%), Positives = 155/289 (53%), Gaps = 12/289 (4%)
Query: 395 LNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDL-QASEHVMDVVEVIHCLTA 453
LN+I+ S YRTA KL+ VQ +LDL+ + ++ +A +H + V ++ L
Sbjct: 9 LNSIENSIYRTAFKLQSVQTLCQLDLIDSSLIQQVLLRPSFWEARKHSLSVQQLSQALQE 68
Query: 454 LYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQ 513
L+++ EE V+ P +++L+ L +++S +G ++ + + L G K +
Sbjct: 69 LFQKAREENPGQVH-PRAPELTLSLLTTMYNSKGTGFLQLMPAAAALITLSGDSPLSKYR 127
Query: 514 YLFSQVA-------NSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRF 566
LF A +SG + +R L LL + Q+P +GE A VE + RSCF+
Sbjct: 128 ALFQLYAENSRGGYDSGPRMTRRVLRKLLTDLQQIPTFVGESRAL--CPVESATRSCFQ- 184
Query: 567 STGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSL 626
P I+ +FL WV EP ++WL HR++ AE+V H +C++CR PI G RYR L
Sbjct: 185 GVLSPAIKEEKFLSWVQSEPPILLWLPTCHRLSAAERVTHPARCTLCRTFPITGLRYRCL 244
Query: 627 KQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKN 675
K N DICQ CFL+G SK ++ +P++E+ ++ +N + TL+N
Sbjct: 245 KCLNFDICQMCFLSGLHSKSHQKSHPVIEHCIQMSAMQNTKLLFRTLRN 293
>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
Length = 743
Score = 152 bits (384), Expect = 1e-36
Identities = 147/561 (26%), Positives = 243/561 (43%), Gaps = 86/561 (15%)
Query: 394 DLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEH--VMDVVEVIHCL 451
DL+ I+ S YRTA KLR VQK L LV + +E E+ L + ++V + L
Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85
Query: 452 TALYERLEEERGIL--VNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVK 509
+ ++ +L + ++V + + LN+LL FD GK+ + K +A LCG ++
Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145
Query: 510 EKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTG 569
+KL+Y+FS +++S L E +++P + E +FG + E S RSCF +
Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200
Query: 570 KPVIEASQFLEWVNLEP--QSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLK 627
+ + + FL+ + +P Q +VWL +LHR+ E V H +CS C + GFRYR +
Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260
Query: 628 QFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKHYFSKHP 687
N +CQ CF G A + + + EY + + ++ + + + + S+ HP
Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSRE--PLHP 318
Query: 688 QRGYLPVQSVLEADYSETPASSPMWPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDD 747
P + + A +T WP S + S + S F S P D
Sbjct: 319 MFPDQPEKPLNLAHIVDT------WPPRPVTSMNDTLFSH--SVPSSGSPFITRSSPPKD 370
Query: 748 SIDEDQYLLRHSSPITDREPAFGQQAPCSVATESKGE-----------------LQKILA 790
S E LL ++P + G Q +VA E + +
Sbjct: 371 SEVEQNKLLARAAPAFLK--GKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSN 428
Query: 791 HLEDENRILQGELRRL-----KWQHEEAAEAPSLA---DGSTE-----AATDHRNEE--- 834
L++E+R++ RL Q + AP ++ D + + A +++N E
Sbjct: 429 RLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANKQQRQLIAELENKNREILQ 488
Query: 835 -------------------------LLAEARILRQHKSRLETRMQILEDHNKQLESQLQR 869
LLAE R+LRQ K LE RM L++ ++L QL+
Sbjct: 489 EIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEG 548
Query: 870 LRELLLQPPTESDGSGSAGSS 890
L +LL ++ G+GS SS
Sbjct: 549 LMKLL-----KTQGAGSPRSS 564
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,086,932
Number of Sequences: 37866
Number of extensions: 1709440
Number of successful extensions: 9257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 7809
Number of HSP's gapped (non-prelim): 1476
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.