Guide to the Human Genome
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Search of human proteins with 14702171

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14702171 DNA directed RNA polymerase II polypeptide C [Homo
sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14702171 DNA directed RNA polymerase II polypeptide C [Homo s...   561   e-160
gi|42560246 RNA polymerase I subunit isoform 1 [Homo sapiens]         100   1e-21
gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]          100   1e-21
gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i...    32   0.60 
gi|47933339 RNA binding motif protein 15 [Homo sapiens]                31   1.3  
gi|19482174 cullin 2 [Homo sapiens]                                    30   1.8  
gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide i...    28   6.7  
gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide iso...    28   6.7  
gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                         28   8.7  

>gi|14702171 DNA directed RNA polymerase II polypeptide C [Homo
           sapiens]
          Length = 275

 Score =  561 bits (1446), Expect = e-160
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH 60
           MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH
Sbjct: 1   MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH 60

Query: 61  DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL 120
           DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL
Sbjct: 61  DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL 120

Query: 121 ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA 180
           ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA
Sbjct: 121 ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA 180

Query: 181 GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR 240
           GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR
Sbjct: 181 GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR 240

Query: 241 PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN 275
           PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Sbjct: 241 PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN 275


>gi|42560246 RNA polymerase I subunit isoform 1 [Homo sapiens]
          Length = 346

 Score =  100 bits (250), Expect = 1e-21
 Identities = 64/199 (32%), Positives = 105/199 (52%), Gaps = 15/199 (7%)

Query: 9   VRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRL 68
           V +  + + +++F +   D A+AN+ RR+ +AEVP +A++ V +  N+S++ DE +AHRL
Sbjct: 51  VDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRL 110

Query: 69  GLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRC---------NEDQTRHVTSRD 119
           GLIP+ +D  + + +   D   EE     +++F L VRC         + D      +  
Sbjct: 111 GLIPIHADPRLFEYRNQGD---EEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHK 167

Query: 120 LISNSPRVIPVTSRNRDNDPNDYVE--QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWN 177
           + +     IP+     D  P   +    DDILI +LR GQE+ L  +  KG GK+HAK++
Sbjct: 168 VYTRHMTWIPL-GNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFS 226

Query: 178 PTAGVAFEYDPDNALRHTV 196
           P A  ++   PD  L   V
Sbjct: 227 PVATASYRLLPDITLLEPV 245


>gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]
          Length = 342

 Score =  100 bits (250), Expect = 1e-21
 Identities = 64/199 (32%), Positives = 105/199 (52%), Gaps = 15/199 (7%)

Query: 9   VRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRL 68
           V +  + + +++F +   D A+AN+ RR+ +AEVP +A++ V +  N+S++ DE +AHRL
Sbjct: 51  VDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRL 110

Query: 69  GLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRC---------NEDQTRHVTSRD 119
           GLIP+ +D  + + +   D   EE     +++F L VRC         + D      +  
Sbjct: 111 GLIPIHADPRLFEYRNQGD---EEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHK 167

Query: 120 LISNSPRVIPVTSRNRDNDPNDYVE--QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWN 177
           + +     IP+     D  P   +    DDILI +LR GQE+ L  +  KG GK+HAK++
Sbjct: 168 VYTRHMTWIPL-GNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFS 226

Query: 178 PTAGVAFEYDPDNALRHTV 196
           P A  ++   PD  L   V
Sbjct: 227 PVATASYRLLPDITLLEPV 245


>gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like
           isoform a [Homo sapiens]
          Length = 357

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 11/77 (14%)

Query: 191 ALRHTVYPKPEEWPKSEYSELDEDE---SQAPYDPNGKPERFYYNVESCGSLRPETIVLS 247
           ALRH      EEW   E+  L  +E   S+ P DP G  +          +  P T+ L 
Sbjct: 27  ALRHGELELKEEWQDEEFPRLLPEEAGTSEDPEDPKGDSQ--------AAAGTPSTLALC 78

Query: 248 ALSGLKKKLSDLQTQLS 264
               ++K+LS  + +LS
Sbjct: 79  GQRPMRKRLSAPELRLS 95


>gi|47933339 RNA binding motif protein 15 [Homo sapiens]
          Length = 977

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 10/71 (14%)

Query: 152 KLRKGQELRLRAYAKKGFGKEH----------AKWNPTAGVAFEYDPDNALRHTVYPKPE 201
           KL    ++ +R   K G+GK              W P A +A E+D    +R   Y K +
Sbjct: 431 KLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGD 490

Query: 202 EWPKSEYSELD 212
            W   +Y  LD
Sbjct: 491 SWAYIQYESLD 501


>gi|19482174 cullin 2 [Homo sapiens]
          Length = 745

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 4/102 (3%)

Query: 78  IVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDN 137
           ++D    + D   E+   E S  F+L++  +  +T+   +  +  ++P+ +  T    D 
Sbjct: 617 LLDVKMINHDSEKEDIDAESS--FSLNMNFSSKRTKFKITTSMQKDTPQEMEQTRSAVDE 674

Query: 138 DPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPT 179
           D   Y++   + I+K RK   LR  A  ++   +  A++NP+
Sbjct: 675 DRKMYLQAAIVRIMKARK--VLRHNALIQEVISQSRARFNPS 714


>gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
           isoform A [Homo sapiens]
          Length = 357

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)

Query: 185 EYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKP 226
           E + +   R TV PK EE  + E  E +E+E +   +  G+P
Sbjct: 36  EEEAEEEARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQP 77


>gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
           isoform B [Homo sapiens]
          Length = 353

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 14/42 (33%), Positives = 22/42 (52%)

Query: 185 EYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKP 226
           E + +   R TV PK EE  + E  E +E+E +   +  G+P
Sbjct: 36  EEEAEEEARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQP 77


>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 12/101 (11%)

Query: 125 PRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAF 184
           PR++      R+ D      Q++    +L+  ++ +L A  + G G     W    G   
Sbjct: 382 PRMVVTNLLTRNQDKQRQKRQEEQKQQQLK--EQKKLIAMLENGLGLPPGMWELLGGPK- 438

Query: 185 EYDPDNALRHTVYP------KPEEWPKSEYSELDEDESQAP 219
              PD+ ++    P       P+  P S+ SE+ +  SQAP
Sbjct: 439 ---PDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAP 476


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,715,154
Number of Sequences: 37866
Number of extensions: 498317
Number of successful extensions: 1329
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1321
Number of HSP's gapped (non-prelim): 9
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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