Guide to the Human Genome
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Search of human proteins with 14550416

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
         (515 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]              1059   0.0  
gi|157694526 Fc receptor-like 5 [Homo sapiens]                        319   3e-87
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]               318   7e-87
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]               276   2e-74
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]    179   7e-45
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]    179   7e-45
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]     179   7e-45
gi|50878302 Fc receptor-like B [Homo sapiens]                         176   5e-44
gi|157057547 Fc receptor-like 6 [Homo sapiens]                        158   1e-38
gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64...   155   6e-38
gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]          124   2e-28
gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Hom...   107   3e-23
gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isofo...   107   3e-23
gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isofo...   107   3e-23
gi|4503675 Fc fragment of IgE, high affinity I, receptor for; al...   105   1e-22
gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isofo...   101   1e-21
gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isofo...   101   1e-21
gi|210031822 Fc fragment of IgG, low affinity IIa, receptor isof...    95   1e-19
gi|50511936 Fc fragment of IgG, low affinity IIa, receptor isofo...    90   4e-18
gi|63055063 Fc fragment of IgG, high affinity Ib, receptor (CD64...    89   1e-17
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s...    83   5e-16
gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor (CD...    80   6e-15
gi|132814489 low affinity immunoglobulin gamma Fc region recepto...    80   6e-15
gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor (CD...    79   8e-15
gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor (CD...    79   8e-15
gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor (CD...    79   8e-15
gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD1...    79   8e-15
gi|157168355 CD22 molecule [Homo sapiens]                              73   5e-13
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...    62   2e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    60   4e-09

>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
          Length = 515

 Score = 1059 bits (2739), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR
Sbjct: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60

Query: 61  HYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLV 120
           HYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLV
Sbjct: 61  HYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLV 120

Query: 121 LRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180
           LRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSN
Sbjct: 121 LRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180

Query: 181 FKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240
           FKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW
Sbjct: 181 FKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240

Query: 241 STYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQA 300
           STYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQA
Sbjct: 241 STYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQA 300

Query: 301 VEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCT 360
           VEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCT
Sbjct: 301 VEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCT 360

Query: 361 ADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGF 420
           ADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGF
Sbjct: 361 ADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGF 420

Query: 421 LGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTS 480
           LGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTS
Sbjct: 421 LGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTS 480

Query: 481 RTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES 515
           RTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES
Sbjct: 481 RTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES 515


>gi|157694526 Fc receptor-like 5 [Homo sapiens]
          Length = 977

 Score =  319 bits (818), Expect = 3e-87
 Identities = 177/379 (46%), Positives = 226/379 (59%), Gaps = 6/379 (1%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW  LL  APV GQ A   +P+I + PPWTT F+GERVTLTC GF+FY+ +KT WYHR
Sbjct: 1   MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60

Query: 61  HYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLV 120
           +   E L  TP N LEV+ESG YRCQA+GSP S+PV L FSS SLILQAP SVFEGD++V
Sbjct: 61  YLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVV 120

Query: 121 LRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180
           LRC  + +  L    Y  N N+L+  NK  D  IP A   +NG YRC GY +      SN
Sbjct: 121 LRCRAKAEVTLNNTIYK-NDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSN 179

Query: 181 FKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240
              I++QE F  P L+A+  QP  GN V L+CETQL  ERSD PL F FFRD + +   W
Sbjct: 180 TVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW 239

Query: 241 STYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQA 300
           S  P  Q+  +W ++SG YWC A T+  ++   SP   I VQ IP S  +L   P     
Sbjct: 240 SLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ-IPASHPVLTLSPEKALN 298

Query: 301 VEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCT 360
            EG  + L C   E +  T + ++ E +   L  K+ R  R      ++   ++G YYCT
Sbjct: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGV--PLRHKSVRCERGASISFSLTTENSGNYYCT 356

Query: 361 ADNSYG--PVQSMVLNVTV 377
           ADN  G  P +++ L+VTV
Sbjct: 357 ADNGLGAKPSKAVSLSVTV 375



 Score =  129 bits (324), Expect = 6e-30
 Identities = 142/508 (27%), Positives = 220/508 (43%), Gaps = 55/508 (10%)

Query: 23  PVISVHPPWTTFFKGERVTLTCNG--------FQFYATEKTTWYHRHYWGEKLTLTPGNT 74
           PV+++       F+G  VTL C          +QFY  +   W        +++ +   +
Sbjct: 473 PVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFS--FS 530

Query: 75  LEVRESGLYRCQAR---GSPRSNPVRLLF----SSDSLILQAPYS-VFEGDTLVLRCHRR 126
           L    SG Y C A    G  RS  V L      S   L L+ P +    GD L L C   
Sbjct: 531 LTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAP 590

Query: 127 RKEKLTAVKYTWNGNILSISNK------SWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180
           R        +      L  S+       S++L +   ++ ++GNY C      N +   +
Sbjct: 591 RGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSL---TAEHSGNYSCEA---NNGLVAQH 644

Query: 181 FKIIKIQELFP--HPEL--KATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI 236
              I +  + P   P L  +A  +Q   G+ + L CE      R  +P+ + F+ + +V 
Sbjct: 645 SDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEAL----RGSSPILYWFYHE-DVT 699

Query: 237 LSDWSTYP------ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVL 290
           L   S          L L T   E+SG Y C A+   G   + S  + + V  +PVS  +
Sbjct: 700 LGKISAPSGGGASFNLSLTT---EHSGIYSCEADN--GLEAQRSEMVTLKVA-VPVSRPV 753

Query: 291 LETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIR 350
           L  +  G  A  G++L L C    G+    + +  ED+  +LG ++  S  A L L ++ 
Sbjct: 754 LTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDV--TLGNRSSPSGGASLNL-SLT 810

Query: 351 QSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLS-ALLLAVALLFH 409
             H+G Y C ADN  G  +S  + + +     NR G  A G  GGLLS A L A ALL +
Sbjct: 811 AEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLY 870

Query: 410 CWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTT 469
           CW  RK+G     D  R P      E ++   PA  ELQ +Y + +P+  ++VYSE++  
Sbjct: 871 CWLSRKAGRKPASDPARSPSDSDSQEPTYHNVPAWEELQPVYTNANPRGENVVYSEVRII 930

Query: 470 QLGEEEEANTSRTLLEDKDVSVVYSEVK 497
           Q  ++    +    L +K   ++YSEVK
Sbjct: 931 QEKKKHAVASDPRHLRNKGSPIIYSEVK 958



 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 95/375 (25%), Positives = 156/375 (41%), Gaps = 53/375 (14%)

Query: 37  GERVTLTCNG------------FQFYATEKTTWYHRHYWGEKLTLTPGNTLEV---RESG 81
           G  VTLTC              F+F+  ++T        G   +L+P   +     ++SG
Sbjct: 204 GNPVTLTCETQLSLERSDVPLRFRFFRDDQTL-------GLGWSLSPNFQITAMWSKDSG 256

Query: 82  LYRCQAR--------GSPRSNPVRLLFSSDSLILQAPYSV--FEGDTLVLRCHRRRKEKL 131
            Y C+A          SPRS     + +S  ++  +P     FEG  + L C  +     
Sbjct: 257 FYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLR 316

Query: 132 TAVKYTWNGNIL---SISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQE 188
           T  ++   G  L   S+  +    +    ++ N+GNY C     +N +     K + +  
Sbjct: 317 TLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTA---DNGLGAKPSKAVSLSV 373

Query: 189 LFP--HPELKATDSQPT--EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI--LSDWST 242
             P  HP L  +  +    EG  V L CE Q    R   P+ + F  +G  +   S  S 
Sbjct: 374 TVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQ----RGSLPILYQFHHEGAALERRSANSA 429

Query: 243 YPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVE 302
                  ++  E+SG+Y+C A+   G     + SL + V   PVS  +L    +     E
Sbjct: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---PVSHPVLTLSSAEALTFE 486

Query: 303 GEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTAD 362
           G  + L C V  G+    + ++ EDM   L   +  S+       ++ + H+G YYCTAD
Sbjct: 487 GATVTLHCEVQRGSPQILYQFYHEDM--PLWSSSTPSVGRVSFSFSLTEGHSGNYYCTAD 544

Query: 363 NSYGPVQSMVLNVTV 377
           N +GP +S V+++ V
Sbjct: 545 NGFGPQRSEVVSLFV 559



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 95/389 (24%), Positives = 159/389 (40%), Gaps = 57/389 (14%)

Query: 23  PVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGN--------- 73
           PV+++  P    F+G +VTL C   +         Y  H+ G  L     N         
Sbjct: 380 PVLNLSSPEDLIFEGAKVTLHC---EAQRGSLPILYQFHHEGAALERRSANSAGGVAISF 436

Query: 74  TLEVRESGLYRCQARGS---------------PRSNPVRLLFSSDSLILQAPYSVFEGDT 118
           +L    SG Y C A                  P S+PV  L S+++L        FEG T
Sbjct: 437 SLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEAL-------TFEGAT 489

Query: 119 LVLRCHRRRKEKLTAVKY------TWNGNILSISNKSWDLLIPQASSNNNGNYRCI---G 169
           + L C  +R       ++       W+ +  S+   S+   + +  S   GNY C    G
Sbjct: 490 VTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHS---GNYYCTADNG 546

Query: 170 YGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNF 229
           +G +     S F  + +    P   L+   +Q   G+ + L CE    P  S   L++ +
Sbjct: 547 FGPQRSEVVSLFVTVPVSR--PILTLRVPRAQAVVGDLLELHCEA---PRGSPPILYWFY 601

Query: 230 FRDGEVILSDWSTYPELQLP-TVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSG 288
             D  +  S   +  E     ++  E+SG+Y C  E   G + +HS ++ + V  +PVS 
Sbjct: 602 HEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSC--EANNGLVAQHSDTISLSV-IVPVSR 658

Query: 289 VLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPA 348
            +L  +    QAV G++L L C    G+    + ++ ED+  +LG+ +  S        +
Sbjct: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDV--TLGKISAPSGGGASFNLS 716

Query: 349 IRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
           +   H+G Y C ADN     +S ++ + V
Sbjct: 717 LTTEHSGIYSCEADNGLEAQRSEMVTLKV 745



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 80/322 (24%), Positives = 136/322 (42%), Gaps = 34/322 (10%)

Query: 77  VRESGLYRCQARGSP----RSNPVRLLFSSD---SLILQAPYSVFEGDTLVLRCHRR--- 126
           ++++G YRC           SN V++         ++  + +    G+ + L C  +   
Sbjct: 158 LKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSL 217

Query: 127 -RKEKLTAVKYTWNGNILSIS-NKSWDLLIPQASSNNNGNYRC----IGYGDENDVFRSN 180
            R +     ++  +   L +  + S +  I    S ++G Y C    + Y   +D  RS 
Sbjct: 218 ERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRS- 276

Query: 181 FKIIKIQELFPHPELKATDSQPT--EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILS 238
              I++Q    HP L  +  +    EG  V L CETQ    R+     + F+ +G V L 
Sbjct: 277 --WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRT----LYRFYHEG-VPLR 329

Query: 239 DWSTYPELQLP---TVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQP 295
             S   E       ++  ENSG+Y+C A+   G     + SL + V   PVS  +L    
Sbjct: 330 HKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTV---PVSHPVLNLSS 386

Query: 296 SGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAG 355
                 EG  + L C    G+    + +H E    +L R++  S        ++   H+G
Sbjct: 387 PEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGA--ALERRSANSAGGVAISFSLTAEHSG 444

Query: 356 GYYCTADNSYGPVQSMVLNVTV 377
            YYCTADN +GP +S  ++++V
Sbjct: 445 NYYCTADNGFGPQRSKAVSLSV 466


>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
          Length = 734

 Score =  318 bits (815), Expect = 7e-87
 Identities = 172/382 (45%), Positives = 234/382 (61%), Gaps = 9/382 (2%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQF-YATEKTTWYH 59
           MLLW  LL   P   QS  A K V+ ++PPW+T FKGE+V L C+      A   T WYH
Sbjct: 1   MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60

Query: 60  RHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTL 119
                EKL     + +++ E G Y+C+ RGS  S+ V + FS D LILQA + VFEGD +
Sbjct: 61  ----DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNV 116

Query: 120 VLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDEN--DVF 177
           +LRC  +  +      Y  +G  L  ++ + + +   + S +N  Y C  Y      D+ 
Sbjct: 117 ILRCQGKDNKNTHQKVYYKDGKQLP-NSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIE 175

Query: 178 RSNFKI-IKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI 236
            ++  + I++QELF HP L+A+ S P EG+ + L+CETQL P+R D  L F+ FRD + +
Sbjct: 176 VTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL 235

Query: 237 LSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPS 296
              WS  P LQ+P +W E+SGSYWC  ETV  +I K S   QI VQR+PVS V LE +P+
Sbjct: 236 GLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPT 295

Query: 297 GGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGG 356
           GGQ +EGE +VL+CSVA+G+G  TFSWH+E    SLGRKTQRSL AEL +  +++S AG 
Sbjct: 296 GGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGR 355

Query: 357 YYCTADNSYGPVQSMVLNVTVR 378
           YYC ADN + P+ S  + VTVR
Sbjct: 356 YYCAADNVHSPILSTWIRVTVR 377



 Score =  150 bits (380), Expect = 2e-36
 Identities = 134/471 (28%), Positives = 215/471 (45%), Gaps = 52/471 (11%)

Query: 79  ESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS------------VFEGDTLVLRCHRR 126
           +SG Y C+      S   R L  S   + + P S            + EG+ +VL C   
Sbjct: 254 DSGSYWCEVETVTHSIKKRSL-RSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVA 312

Query: 127 RKEKLTAVKYTWNGNILSISNKSWDLLIPQ-----ASSNNNGNYRCIGYGDENDVFRSNF 181
           +        +   G + S+  K+   L+ +        ++ G Y C      + +  +  
Sbjct: 313 QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWI 372

Query: 182 KI-IKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240
           ++ ++I    P    +A  +    G+ + L CE+     R   P+ + F+ + +V L + 
Sbjct: 373 RVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESL----RGSPPILYRFYHE-DVTLGNS 427

Query: 241 STYP------ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQ 294
           S          L L     E+SG+Y C A+   G  H H  SL++ V   PVS  +L  +
Sbjct: 428 SAPSGGGASFNLSLTA---EHSGNYSCDADNGLGAQHSHGVSLRVTV---PVSRPVLTLR 481

Query: 295 PSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHA 354
             G QAV G++L L C    G+    + ++ ED  ++LG  +  S        ++   H+
Sbjct: 482 APGAQAVVGDLLELHCESLRGSFPILYWFYHED--DTLGNISAHSGGGASFNLSLTTEHS 539

Query: 355 GGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVA--LLFHCWR 412
           G Y C ADN  G   S V+ + V  T  NR GL AAG TG +LS L+LA A  LL +   
Sbjct: 540 GNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARA 599

Query: 413 RRK-SGVGFLGDETRLP-----PAPG------PGESSHSICPAQVELQSLYVDVHPKKGD 460
           RRK  G+   G  +  P     P+        P E +HS   A +EL+ +Y +V+P   +
Sbjct: 600 RRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSN 659

Query: 461 LVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSK 511
            +YS+I + Q  +E  AN      E ++++V+YSE+K  HPD+SAG+ SS+
Sbjct: 660 PIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSR 710


>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
          Length = 508

 Score =  276 bits (707), Expect = 2e-74
 Identities = 152/305 (49%), Positives = 195/305 (63%), Gaps = 13/305 (4%)

Query: 102 SDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNN 161
           +DSL L AP SVFEGD++VL+C   +  K+  + Y  +   LS+  K  D LI  A  ++
Sbjct: 17  ADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSD 76

Query: 162 NGNYRCIGYGDENDVF----RSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLP 217
           +GNY C   G    +F     SN   IK+QELF  P L A+  QP EG  V+L CET+L 
Sbjct: 77  SGNYFCSTKGQ---LFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLS 133

Query: 218 PERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSL 277
           P+R D  L F FFR+ +V+ S WS+ PELQ+  VW E++GSYWC AETV   I K S   
Sbjct: 134 PQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193

Query: 278 QIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQ 337
           QIHVQRIP+S V LE +  GGQ  EG+ L+L+CSVA GTG+ TFSW+RE    S+G+KTQ
Sbjct: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253

Query: 338 RSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLV-----AAGA 392
           RSL AELE+PA+++S AG YYC ADN + P+QS V+N+ VR  P +R  L      A  A
Sbjct: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVR-IPVSRPVLTLRSPGAQAA 312

Query: 393 TGGLL 397
            G LL
Sbjct: 313 VGDLL 317



 Score =  138 bits (347), Expect = 1e-32
 Identities = 143/527 (27%), Positives = 236/527 (44%), Gaps = 51/527 (9%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW+ L+ F  V  Q+ +     +++  P ++ F+G+ + L C G Q +  +K   YH+
Sbjct: 1   MLLWSLLVIFDAVTEQADS-----LTLVAP-SSVFEGDSIVLKCQGEQNWKIQKMA-YHK 53

Query: 61  HYWGEKLTLTPG------NTLEVRESGLYRCQARGS-----PRSNPVRL----LFSSDSL 105
               ++L++          +  + +SG Y C  +G        SN V++    LF    L
Sbjct: 54  D--NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVL 111

Query: 106 ILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTW-----NGNILSISNKSWDLLIPQASSN 160
              + +   EG  + L+C  R   +   V+  +     N  + S  + S +L I    S 
Sbjct: 112 TASS-FQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170

Query: 161 NNGNYRC----IGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQL 216
           + G+Y C    + +       +S   + +I       E++A   Q TEG  + L C    
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVA- 229

Query: 217 PPERSDTPLHFNFFRDGEVILSDWSTY----PELQLPTVWRENSGSYWCGAETVRGNIHK 272
                   + F+++R+         T      EL++P V   ++G Y+C A+   G++  
Sbjct: 230 ---GGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADN--GHVPI 284

Query: 273 HSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESL 332
            S  + I V RIPVS  +L  +  G QA  G++L L C    G+    + ++ ED+  +L
Sbjct: 285 QSKVVNIPV-RIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDV--TL 341

Query: 333 GRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGA 392
           G  +  S        ++   H+G Y C A+N  G   S  + V++    G R  L+ AG 
Sbjct: 342 GNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGV 401

Query: 393 TGGLLSAL-LLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSI-CPAQVELQSL 450
             GL   L    VALL +    + SG     +E R    P P E ++S   P   ELQ +
Sbjct: 402 LWGLFGVLGFTGVALLLYALFHKISGESSATNEPRGASRPNPQEFTYSSPTPDMEELQPV 461

Query: 451 YVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVK 497
           YV+V     D+VYS++ + Q  + E +   RTLLE+KD  V+YS VK
Sbjct: 462 YVNVGSVDVDVVYSQVWSMQ--QPESSANIRTLLENKDSQVIYSSVK 506


>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
          Length = 428

 Score =  179 bits (453), Expect = 7e-45
 Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)

Query: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254
           L A+ S PTEG+ V L+C+     + SD    F FFRD   +   WS+ P+LQ+  +W+E
Sbjct: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79

Query: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
           ++GSYWC A+T+   + +   S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA 
Sbjct: 80  DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138

Query: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
           GTGD TF W++  +  +L  KTQRSL AE E+P++R+S A  YYC A+N YGP  S +++
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198

Query: 375 VTVR 378
           +TVR
Sbjct: 199 ITVR 202



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 79/255 (30%), Positives = 123/255 (48%), Gaps = 8/255 (3%)

Query: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303
           E ++P+V   ++  Y+C AE    N +  SPS  + +  RIPVS  +L  +    QA   
Sbjct: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222

Query: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363
           ++L L C    G+    + ++ ED+  +LG ++  S        ++ + H+G Y C A+N
Sbjct: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280

Query: 364 SYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLA-VALLFHCWRRRKSGVGFLG 422
             G  +S  + +      G R   + +G   GLLS L  A VALLF    +RK G     
Sbjct: 281 GLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSAR 340

Query: 423 DETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRT 482
           D  R  P+P P E ++   P   +LQ +Y +V+   GD VYS     Q  +E  A T  T
Sbjct: 341 DPLRSLPSPLPQEFTYLNSPTPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAETLGT 400

Query: 483 LLEDKDVSVVYSEVK 497
            +EDK    +YS ++
Sbjct: 401 HMEDKVSLDIYSRLR 415


>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
          Length = 366

 Score =  179 bits (453), Expect = 7e-45
 Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)

Query: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254
           L A+ S PTEG+ V L+C+     + SD    F FFRD   +   WS+ P+LQ+  +W+E
Sbjct: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79

Query: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
           ++GSYWC A+T+   + +   S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA 
Sbjct: 80  DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138

Query: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
           GTGD TF W++  +  +L  KTQRSL AE E+P++R+S A  YYC A+N YGP  S +++
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198

Query: 375 VTVR 378
           +TVR
Sbjct: 199 ITVR 202



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 9/139 (6%)

Query: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303
           E ++P+V   ++  Y+C AE    N +  SPS  + +  RIPVS  +L  +    QA   
Sbjct: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222

Query: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363
           ++L L C    G+    + ++ ED+  +LG ++  S        ++ + H+G Y C A+N
Sbjct: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280

Query: 364 SYGPVQS--MVLNVTVRET 380
             G  +S  + LN T R +
Sbjct: 281 GLGAQRSEAVTLNFTGRRS 299


>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
          Length = 429

 Score =  179 bits (453), Expect = 7e-45
 Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)

Query: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254
           L A+ S PTEG+ V L+C+     + SD    F FFRD   +   WS+ P+LQ+  +W+E
Sbjct: 21  LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79

Query: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
           ++GSYWC A+T+   + +   S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA 
Sbjct: 80  DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138

Query: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
           GTGD TF W++  +  +L  KTQRSL AE E+P++R+S A  YYC A+N YGP  S +++
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198

Query: 375 VTVR 378
           +TVR
Sbjct: 199 ITVR 202



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 79/256 (30%), Positives = 123/256 (48%), Gaps = 9/256 (3%)

Query: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303
           E ++P+V   ++  Y+C AE    N +  SPS  + +  RIPVS  +L  +    QA   
Sbjct: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222

Query: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363
           ++L L C    G+    + ++ ED+  +LG ++  S        ++ + H+G Y C A+N
Sbjct: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280

Query: 364 SYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLA-VALLFHCWRRRKSGVGFLG 422
             G  +S  + +      G R   + +G   GLLS L  A VALLF    +RK G     
Sbjct: 281 GLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSAR 340

Query: 423 DETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEE-EANTSR 481
           D  R  P+P P E ++   P   +LQ +Y +V+   GD VYS     Q  +E   A T  
Sbjct: 341 DPLRSLPSPLPQEFTYLNSPTPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLG 400

Query: 482 TLLEDKDVSVVYSEVK 497
           T +EDK    +YS ++
Sbjct: 401 THMEDKVSLDIYSRLR 416


>gi|50878302 Fc receptor-like B [Homo sapiens]
          Length = 426

 Score =  176 bits (446), Expect = 5e-44
 Identities = 105/282 (37%), Positives = 152/282 (53%), Gaps = 10/282 (3%)

Query: 6   SLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGE 65
           +LL   P  GQ+A   KP++S+HPPWTT FKGERVTL C+G+     E        Y G 
Sbjct: 6   ALLLLVPSSGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTLWYLGH 65

Query: 66  KLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS-VFEGDTLVLRCH 124
            L  +   ++EV+  G+YRCQ RG+P S+P+ L  S+D LILQ PY+ VFEG+ LVLRC 
Sbjct: 66  LLLPSHKKSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPVFEGEPLVLRCR 125

Query: 125 RRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG---YGDENDVFRSNF 181
               + +  + Y  +G  +   + S +  + QA ++++G Y+C G      E+    S  
Sbjct: 126 GWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASDSGRYQCSGTMRIPVESAPMFSAK 185

Query: 182 KIIKIQELFPHPELKATDSQPTEG---NSVNLSCETQLPPERSDTPLHFNFFRDGEVILS 238
             + +QELF  P L+    +   G     V L C+T+L P++ DTPL F F++    +  
Sbjct: 186 VAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQFAFYKYSRAVRR 245

Query: 239 -DWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQI 279
            DW    E  +P    E   SYWC A T   ++ K SP LQ+
Sbjct: 246 FDWGA--EYTVPEPEVEELESYWCEAATATRSVRKRSPWLQL 285


>gi|157057547 Fc receptor-like 6 [Homo sapiens]
          Length = 434

 Score =  158 bits (400), Expect = 1e-38
 Identities = 127/410 (30%), Positives = 189/410 (46%), Gaps = 35/410 (8%)

Query: 105 LILQA-PYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNG 163
           L LQA P  VFEGD L LRC   +   L+ VK+  +G  L  S ++  L +  A+  + G
Sbjct: 20  LYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATVQSRG 79

Query: 164 NYRCIG---YGDENDVFRSNFKIIKIQELFPHPELKATDS-QPTEGNSVNLSCETQLPPE 219
            Y C G   Y  +     S   ++++QELFP P L A  S +P EG+ V L C+T+L P 
Sbjct: 80  QYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHPL 139

Query: 220 RSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQI 279
           RS   L F+F +DG   L D   +PEL +P     +SG YWC      G + K SP L++
Sbjct: 140 RSALRLLFSFHKDGHT-LQDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEV 198

Query: 280 HVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRS 339
            VQ  PVS  +L           G+M+ L+C    G+    +S++ ++            
Sbjct: 199 RVQ-APVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVG-NHSAPCG 256

Query: 340 LRAELELPAIRQSHAGGYYCTADNSYG-----PVQSMVLNVTVRETPGNRDGLVAAGATG 394
               L  P   +  AG Y C A+NS       P +  +    V  TP +    +      
Sbjct: 257 GTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPAS--NWLVPWLPA 314

Query: 395 GLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDV 454
            LL  +++A ALL +    RK+G       +++PP    GE     CP       LY +V
Sbjct: 315 SLLGLMVIAAALLVYVRSWRKAG----PLPSQIPPTAPGGEQ----CP-------LYANV 359

Query: 455 HPKKG---DLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHP 501
           H +KG    +VYS +  T   +  EA ++   +  KD S++ +EV+   P
Sbjct: 360 HHQKGKDEGVVYSVVHRT--SKRSEARSAEFTVGRKDSSIICAEVRCLQP 407



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 78/344 (22%), Positives = 139/344 (40%), Gaps = 45/344 (13%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYH- 59
           MLLW ++L F P  G++   +   +   P     F+G+ +TL C G++     +  +Y  
Sbjct: 1   MLLWTAVLLFVPCVGKTVWLY---LQAWP--NPVFEGDALTLRCQGWKNTPLSQVKFYRD 55

Query: 60  ---RHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQA----PYS 112
               H+  E  TL+ G    V+  G Y C   G     P     +S++ ++Q     P  
Sbjct: 56  GKFLHFSKENQTLSMG-AATVQSRGQYSCS--GQVMYIPQTFTQTSETAMVQVQELFPPP 112

Query: 113 VF---------EGDTLVLRCHRRRKEKLTAVKYTW----NGNILSISNKSWDLLIPQASS 159
           V          EG  + LRC  +     +A++  +    +G+ L       +L IP A  
Sbjct: 113 VLSAIPSPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTLQDRGPHPELCIPGAKE 172

Query: 160 NNNGNYRCIGYGDENDVFRSNFKI-IKIQELFPHP--ELKATDSQPTEGNSVNLSCETQL 216
            ++G Y C    +   V + + ++ +++Q     P   L    + P  G+ V L CE Q 
Sbjct: 173 GDSGLYWCEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQ- 231

Query: 217 PPERSDTPLHFNFFRDGEVI---LSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKH 273
              R   P+ ++F+ D +++    +       L  P    +++G+Y C AE         
Sbjct: 232 ---RGSPPILYSFYLDEKIVGNHSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSE 288

Query: 274 SPSLQIHVQRI---PVSGVLLETQPS---GGQAVEGEMLVLVCS 311
              L +   ++   P S  L+   P+   G   +   +LV V S
Sbjct: 289 PKKLSLKGSQVLFTPASNWLVPWLPASLLGLMVIAAALLVYVRS 332


>gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64)
           [Homo sapiens]
          Length = 374

 Score =  155 bits (393), Expect = 6e-38
 Identities = 105/286 (36%), Positives = 148/286 (51%), Gaps = 11/286 (3%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           M    +LL + PV GQ     K VI++ PPW + F+ E VTL C       +  T W+  
Sbjct: 1   MWFLTTLLLWVPVDGQVDTT-KAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN 59

Query: 61  HYWGEKLTLTPG---NTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF-EG 116
               +  T TP     +  V +SG YRCQ   S RS+P++L      L+LQ    VF EG
Sbjct: 60  GTATQ--TSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEG 117

Query: 117 DTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDV 176
           + L LRCH  + + +  V Y  NG      + + +L I + + ++NG Y C G G     
Sbjct: 118 EPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHR-- 175

Query: 177 FRSNFKIIKIQELFPHPELKATDSQPT-EGNSVNLSCETQLPPERSDTPLHFNFFRDGEV 235
           + S    + ++ELFP P L A+ + P  EGN V LSCET+L  +R    L+F+F+  G  
Sbjct: 176 YTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYM-GSK 234

Query: 236 ILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHV 281
            L   +T  E Q+ T  RE+SG YWC A T  GN+ K SP L++ V
Sbjct: 235 TLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQV 280


>gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]
          Length = 376

 Score =  124 bits (311), Expect = 2e-28
 Identities = 82/224 (36%), Positives = 118/224 (52%), Gaps = 21/224 (9%)

Query: 70  TPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS-VFEGDTLVLRCHRRRK 128
           T  +  + RE+G    Q +    S P  L+ S D LILQ P   VFEGD LVLRC   + 
Sbjct: 65  TEDDLTDAREAGF---QVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQD 121

Query: 129 EKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRS--------- 179
             LT V +  +G+ L     + +  I      ++G+Y C G      +F+S         
Sbjct: 122 WPLTQVTFYRDGSALGPPGPNREFSITVVQKADSGHYHCSG------IFQSPGPGIPETA 175

Query: 180 NFKIIKIQELFPHPELKATDS-QPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILS 238
           +   I +QELFP P L+A  S +P  G+ + LSC+T+LP +RS   L F+F++DG ++ S
Sbjct: 176 SVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQS 235

Query: 239 DWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ 282
              +  E Q+PT   ++SGSYWC A T    + K SP L+I VQ
Sbjct: 236 RGLS-SEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQ 278



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 24/185 (12%)

Query: 204 EGNSVNLSCETQLPPERSDTPL-HFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCG 262
           EG+ + L C+        D PL    F+RDG   L       E  +  V + +SG Y C 
Sbjct: 108 EGDLLVLRCQAW-----QDWPLTQVTFYRDGSA-LGPPGPNREFSITVVQKADSGHYHCS 161

Query: 263 A--ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCS----VAEGT 316
              ++    I + +  + I VQ +  + +L     +  QA  G  + L C     +    
Sbjct: 162 GIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQA--GSPMTLSCQTKLPLQRSA 219

Query: 317 GDTTFSWHREDMQESLGRKTQ-RSLRAELELPAIRQSHAGGYYCTADNSYGPV--QSMVL 373
               FS++++      GR  Q R L +E ++P   + H+G Y+C A      V  QS  L
Sbjct: 220 ARLLFSFYKD------GRIVQSRGLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQL 273

Query: 374 NVTVR 378
            + V+
Sbjct: 274 EIRVQ 278



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 47/219 (21%), Positives = 87/219 (39%), Gaps = 33/219 (15%)

Query: 30  PWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPG-------NTLEVRESGL 82
           P    F+G+ + L C  +Q +   + T+Y     G  L   PG         ++  +SG 
Sbjct: 102 PAKPVFEGDLLVLRCQAWQDWPLTQVTFYRD---GSALG-PPGPNREFSITVVQKADSGH 157

Query: 83  YRCQ------ARGSPRSN-----PVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKL 131
           Y C         G P +       V+ LF +  L          G  + L C  +   + 
Sbjct: 158 YHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQR 217

Query: 132 TAVKYTW----NGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKI-IKI 186
           +A +  +    +G I+     S +  IP AS +++G+Y C    ++N V++ + ++ I++
Sbjct: 218 SAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRV 277

Query: 187 QELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPL 225
           Q         ++ + PT   +   S      PE +  PL
Sbjct: 278 Q------GASSSAAPPTLNPAPQKSAAPGTAPEEAPGPL 310


>gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Homo
           sapiens]
          Length = 323

 Score =  107 bits (266), Expect = 3e-23
 Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 14/177 (7%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW ++L  APV G  AA  K V+ + P W    + + VTLTC G     ++   W+H 
Sbjct: 28  MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHN 87

Query: 61  HYWGEKLTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV 113
                   L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  
Sbjct: 88  G------NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLE 141

Query: 114 F-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           F EG+T+VLRCH  + + L  V +  NG     S    +  IPQA+ +++G+Y C G
Sbjct: 142 FQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG 198



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 55/219 (25%), Positives = 89/219 (40%), Gaps = 38/219 (17%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C     PE    P    +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 65  DSVTLTCRGTHSPESDSIP----WFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 117

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE +VL C           SW
Sbjct: 118 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIVLRCH----------SW 155

Query: 324 HREDM------QESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
             + +      Q    +K  RS      +P    SH+G Y+CT +  Y    S  + +TV
Sbjct: 156 KDKPLVKVTFFQNGKSKKFSRS-DPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITV 214

Query: 378 RETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKS 416
           +    +  G++ A  TG  ++A++ AV  L +C ++R S
Sbjct: 215 QAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRIS 253


>gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isoform
           3 [Homo sapiens]
          Length = 291

 Score =  107 bits (266), Expect = 3e-23
 Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 14/177 (7%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW ++L  APV G  AA  K V+ + P W    + + VTLTC G     ++   W+H 
Sbjct: 28  MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87

Query: 61  HYWGEKLTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV 113
                   L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  
Sbjct: 88  G------NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLE 141

Query: 114 F-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           F EG+T+VLRCH  + + L  V +  NG     S    +  IPQA+ +++G+Y C G
Sbjct: 142 FQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG 198



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 56/219 (25%), Positives = 91/219 (41%), Gaps = 38/219 (17%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C     PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 65  DSVTLTCRGTHSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 117

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE +VL C           SW
Sbjct: 118 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIVLRCH----------SW 155

Query: 324 HREDM------QESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
             + +      Q    +K  RS      +P    SH+G Y+CT +  Y    S  + +TV
Sbjct: 156 KDKPLVKVTFFQNGKSKKFSRS-DPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITV 214

Query: 378 RETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKS 416
           +    +  G++ A  TG  ++A++ AV  L +C ++R S
Sbjct: 215 QAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRIS 253


>gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isoform
           1 [Homo sapiens]
          Length = 310

 Score =  107 bits (266), Expect = 3e-23
 Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 14/177 (7%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW ++L  APV G  AA  K V+ + P W    + + VTLTC G     ++   W+H 
Sbjct: 28  MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87

Query: 61  HYWGEKLTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV 113
                   L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  
Sbjct: 88  G------NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLE 141

Query: 114 F-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           F EG+T+VLRCH  + + L  V +  NG     S    +  IPQA+ +++G+Y C G
Sbjct: 142 FQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG 198



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 56/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C     PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 65  DSVTLTCRGTHSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 117

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE +VL C           SW
Sbjct: 118 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIVLRCH----------SW 155

Query: 324 HREDM------QESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
             + +      Q    +K  RS      +P    SH+G Y+CT +  Y    S  + +TV
Sbjct: 156 KDKPLVKVTFFQNGKSKKFSRS-DPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITV 214

Query: 378 RETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGV 418
           +    +  G++ A  TG  ++A++ AV  L +C ++R S +
Sbjct: 215 QAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISAL 255


>gi|4503675 Fc fragment of IgE, high affinity I, receptor for; alpha
           polypeptide precursor [Homo sapiens]
          Length = 257

 Score =  105 bits (261), Expect = 1e-22
 Identities = 67/171 (39%), Positives = 90/171 (52%), Gaps = 5/171 (2%)

Query: 2   LLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRH 61
           LL  +LL FAP  G  A   KP +S++PPW   FKGE VTLTCNG  F+    T W+H  
Sbjct: 10  LLCVALLFFAPD-GVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNG 68

Query: 62  YWGEKLTLTPGNTLEVR--ESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS-VFEGDT 118
              E+ T +  N +  +  +SG Y+CQ +    S PV L   SD L+LQA    V EG  
Sbjct: 69  SLSEE-TNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQP 127

Query: 119 LVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           L LRCH  R   +  V Y  +G  L    ++ ++ I  A+  ++G Y C G
Sbjct: 128 LFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTG 178



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 32/183 (17%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           +G +V L+C      E S T     +F +G   LS+  T   L +     E+SG Y C  
Sbjct: 43  KGENVTLTCNGNNFFEVSST----KWFHNGS--LSE-ETNSSLNIVNAKFEDSGEYKCQH 95

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
           + V       + S  ++++   V    L  Q S    +EG+ L L C            W
Sbjct: 96  QQV-------NESEPVYLE---VFSDWLLLQASAEVVMEGQPLFLRCH----------GW 135

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHA-----GGYYCTADNSYGPVQSMVLNVTVR 378
              D+ + +  K   +L+   E   I  ++A     G YYCT        +S  LN+TV 
Sbjct: 136 RNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVI 195

Query: 379 ETP 381
           + P
Sbjct: 196 KAP 198


>gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isoform
           4 [Homo sapiens]
          Length = 309

 Score =  101 bits (252), Expect = 1e-21
 Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 15/177 (8%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW ++L  APV G + A  K V+ + P W    + + VTLTC G     ++   W+H 
Sbjct: 28  MLLWTAVLFLAPVAG-TPAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86

Query: 61  HYWGEKLTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV 113
                   L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  
Sbjct: 87  G------NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLE 140

Query: 114 F-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           F EG+T+VLRCH  + + L  V +  NG     S    +  IPQA+ +++G+Y C G
Sbjct: 141 FQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG 197



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 56/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C     PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 64  DSVTLTCRGTHSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 116

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE +VL C           SW
Sbjct: 117 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIVLRCH----------SW 154

Query: 324 HREDM------QESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
             + +      Q    +K  RS      +P    SH+G Y+CT +  Y    S  + +TV
Sbjct: 155 KDKPLVKVTFFQNGKSKKFSRS-DPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITV 213

Query: 378 RETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGV 418
           +    +  G++ A  TG  ++A++ AV  L +C ++R S +
Sbjct: 214 QAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISAL 254


>gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isoform
           2 [Homo sapiens]
          Length = 290

 Score =  101 bits (252), Expect = 1e-21
 Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 15/177 (8%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           MLLW ++L  APV G + A  K V+ + P W    + + VTLTC G     ++   W+H 
Sbjct: 28  MLLWTAVLFLAPVAG-TPAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86

Query: 61  HYWGEKLTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV 113
                   L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  
Sbjct: 87  G------NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLE 140

Query: 114 F-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           F EG+T+VLRCH  + + L  V +  NG     S    +  IPQA+ +++G+Y C G
Sbjct: 141 FQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG 197



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 56/219 (25%), Positives = 91/219 (41%), Gaps = 38/219 (17%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C     PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 64  DSVTLTCRGTHSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 116

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE +VL C           SW
Sbjct: 117 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIVLRCH----------SW 154

Query: 324 HREDM------QESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
             + +      Q    +K  RS      +P    SH+G Y+CT +  Y    S  + +TV
Sbjct: 155 KDKPLVKVTFFQNGKSKKFSRS-DPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITV 213

Query: 378 RETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKS 416
           +    +  G++ A  TG  ++A++ AV  L +C ++R S
Sbjct: 214 QAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRIS 252


>gi|210031822 Fc fragment of IgG, low affinity IIa, receptor isoform
           1 [Homo sapiens]
          Length = 317

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 57/171 (33%), Positives = 85/171 (49%), Gaps = 14/171 (8%)

Query: 7   LLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEK 66
           LL  A    Q+AA  K V+ + PPW    + + VTLTC G +   ++   W+H       
Sbjct: 25  LLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNG----- 79

Query: 67  LTLTPGNT-------LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF-EGDT 118
             L P +T           +SG Y CQ   +  S+PV L   S+ L+LQ P+  F EG+T
Sbjct: 80  -NLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGET 138

Query: 119 LVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
           ++LRCH  + + L  V +  NG     S+      IPQA+ +++G+Y C G
Sbjct: 139 IMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTG 189



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 31/246 (12%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C+    PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 56  DSVTLTCQGARSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 108

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE ++L C   +       ++
Sbjct: 109 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTF 156

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVR-ETPG 382
            +    +         L     +P    SH+G Y+CT +  Y    S  + +TV+  + G
Sbjct: 157 FQNGKSQKFSH-----LDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMG 211

Query: 383 NRD--GLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSI 440
           +    G++ A      ++A++ AV  L +C ++R S      D  +      PG    +I
Sbjct: 212 SSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANS--TDPVKAAQFEPPGRQMIAI 269

Query: 441 CPAQVE 446
              Q+E
Sbjct: 270 RKRQLE 275


>gi|50511936 Fc fragment of IgG, low affinity IIa, receptor isoform
           2 [Homo sapiens]
          Length = 316

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 53/160 (33%), Positives = 80/160 (50%), Gaps = 14/160 (8%)

Query: 18  AAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNT--- 74
           AA  K V+ + PPW    + + VTLTC G +   ++   W+H         L P +T   
Sbjct: 35  AAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNG------NLIPTHTQPS 88

Query: 75  ----LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF-EGDTLVLRCHRRRKE 129
                   +SG Y CQ   +  S+PV L   S+ L+LQ P+  F EG+T++LRCH  + +
Sbjct: 89  YRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDK 148

Query: 130 KLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG 169
            L  V +  NG     S+      IPQA+ +++G+Y C G
Sbjct: 149 PLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTG 188



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 31/246 (12%)

Query: 206 NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWC--GA 263
           +SV L+C+    PE SD+     +F +G +I +   T P  +       +SG Y C  G 
Sbjct: 55  DSVTLTCQGARSPE-SDS---IQWFHNGNLIPTH--TQPSYRFKAN-NNDSGEYTCQTGQ 107

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
            ++   +H            + V    L  Q    +  EGE ++L C   +       ++
Sbjct: 108 TSLSDPVH------------LTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTF 155

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVR-ETPG 382
            +    +         L     +P    SH+G Y+CT +  Y    S  + +TV+  + G
Sbjct: 156 FQNGKSQKFSH-----LDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMG 210

Query: 383 NRD--GLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSI 440
           +    G++ A      ++A++ AV  L +C ++R S      D  +      PG    +I
Sbjct: 211 SSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANS--TDPVKAAQFEPPGRQMIAI 268

Query: 441 CPAQVE 446
              Q+E
Sbjct: 269 RKRQLE 274


>gi|63055063 Fc fragment of IgG, high affinity Ib, receptor (CD64)
           isoform a [Homo sapiens]
          Length = 280

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 60/175 (34%), Positives = 86/175 (49%), Gaps = 7/175 (4%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           M    +LL + PV GQ     K VI++ PPW + F+ E VTL C       +  T W+  
Sbjct: 1   MWFLTTLLLWVPVDGQVDTT-KAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN 59

Query: 61  HYWGEKLTLTPG---NTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF-EG 116
               +  T TP     +  V +SG YRCQ   S RS+P++L      L+LQ    VF EG
Sbjct: 60  GTATQ--TSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFMEG 117

Query: 117 DTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYG 171
           + L LRCH  + + +  V Y  NG      + + +L I + + ++NG Y C G G
Sbjct: 118 EPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMG 172


>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
           sapiens]
          Length = 738

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 91/372 (24%), Positives = 155/372 (41%), Gaps = 51/372 (13%)

Query: 157 ASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKA-TDSQPTEGNSVNLSCETQ 215
           AS +++G Y C   G +  V +SN   I + E+   P +      +  +G ++ + CE+ 
Sbjct: 376 ASKSDSGTYICTA-GIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESI 434

Query: 216 LPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGS---YWCGAETVRGNIHK 272
                   P+ +   +  +V+ +      +   P V+++N      Y C A+    N H 
Sbjct: 435 ----SGTLPISYQLLKTSKVLENSTKNSND---PAVFKDNPTEDVEYQCVAD----NCHS 483

Query: 273 HSPSLQIHVQRIPVSGVLLETQPS--GGQAVE-GEMLVLVCSVAEGTGDTTFSWHREDMQ 329
           H+  L   V R+ V   + E Q S    + VE GE +VL C+V EG+G  T+ ++RE   
Sbjct: 484 HAKMLS-EVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEG 542

Query: 330 ESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSM----VLNVTVRETPGNRD 385
           +   + T  + +A        +   G YYCTA N      S+    +L V V   P  + 
Sbjct: 543 KPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKK- 601

Query: 386 GLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQV 445
           GL+A    G +++ L++A      C+  RK+    +  E   P  P    ++  +    +
Sbjct: 602 GLIAVVIIGVIIALLIIAA----KCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNM 657

Query: 446 ELQSLY---------------VDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVS 490
           E  S Y                +  P   D+ Y+E+Q +     ++       L  KD  
Sbjct: 658 EANSHYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKD-------LGKKDTE 710

Query: 491 VVYSEVKTQHPD 502
            VYSEV+   PD
Sbjct: 711 TVYSEVRKAVPD 722



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 54/227 (23%), Positives = 101/227 (44%), Gaps = 30/227 (13%)

Query: 157 ASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQL 216
           A   ++GNY C    + + + + +  ++ I ELF  PEL+++ +   +G  +NLSC    
Sbjct: 294 AMVEHSGNYTC--KVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPG 351

Query: 217 PPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPS 276
            P     P +F   ++ + I+S    + ++      + +SG+Y C A      + K S +
Sbjct: 352 AP-----PANFTIQKE-DTIVSQTQDFTKI----ASKSDSGTYICTAGI--DKVVKKSNT 399

Query: 277 LQIHV-QRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRK 335
           +QI V + +    +  + Q    + ++G+ + + C    GT     S+      + L   
Sbjct: 400 VQIVVCEMLSQPRISYDAQ---FEVIKGQTIEVRCESISGT--LPISYQLLKTSKVLENS 454

Query: 336 TQRSLRAELELPAIRQSHAG---GYYCTADN--SYGPVQSMVLNVTV 377
           T+ S       PA+ + +      Y C ADN  S+  + S VL V V
Sbjct: 455 TKNS-----NDPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKV 496


>gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor
           (CD16a) isoform b precursor [Homo sapiens]
          Length = 289

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 60/184 (32%), Positives = 86/184 (46%), Gaps = 15/184 (8%)

Query: 2   LLWASLLAFAPVCGQSAAAH----KPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTW 57
           ++W  LL  A +   SA       K V+ + P W    + + VTL C G        T W
Sbjct: 36  IMWQLLLPTALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQW 95

Query: 58  YHRHYWGEKLTLTPGNTL-----EVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS 112
           +H     E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP  
Sbjct: 96  FHN----ESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRW 151

Query: 113 VF-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG-Y 170
           VF E D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G +
Sbjct: 152 VFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLF 211

Query: 171 GDEN 174
           G +N
Sbjct: 212 GSKN 215



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV  ++SG Y C  
Sbjct: 74  EKDSVTLKCQGAYSPEDNST----QWFHNESLISSQASSY-FIDAATV--DDSGEYRC-- 124

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 125 ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 176

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q   GRK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 177 ----LQNGKGRKYFHH-NSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITI--TQGL 229

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++    G   +  L + LLF
Sbjct: 230 AVSTISSFFPPGYQVSFCLVMVLLF 254


>gi|132814489 low affinity immunoglobulin gamma Fc region receptor
           III-B precursor [Homo sapiens]
          Length = 233

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 60/195 (30%), Positives = 87/195 (44%), Gaps = 10/195 (5%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           +LL  +LL       ++    K V+ + P W +  + + VTL C G        T W+H 
Sbjct: 4   LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHN 63

Query: 61  HYWGEKLTLTPGNTL-----EVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF- 114
               E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP  VF 
Sbjct: 64  ----ENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFK 119

Query: 115 EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDEN 174
           E D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G     
Sbjct: 120 EEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSK 179

Query: 175 DVFRSNFKIIKIQEL 189
           +V      I   Q L
Sbjct: 180 NVSSETVNITITQGL 194



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 48/205 (23%), Positives = 83/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV   +SG Y C  
Sbjct: 39  EKDSVTLKCQGAYSPEDNST----QWFHNENLISSQASSY-FIDAATV--NDSGEYRC-- 89

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 90  ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 141

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q    RK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 142 ----LQNGKDRKYFHH-NSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITI--TQGL 194

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++ +  G   +  L + LLF
Sbjct: 195 AVSTISSFSPPGYQVSFCLVMVLLF 219


>gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor
           (CD16a) isoform d precursor [Homo sapiens]
          Length = 253

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 58/180 (32%), Positives = 82/180 (45%), Gaps = 11/180 (6%)

Query: 2   LLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRH 61
           LL  + L      G      K V+ + P W    + + VTL C G        T W+H  
Sbjct: 4   LLLPTALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHN- 62

Query: 62  YWGEKLTLTPGNTL-----EVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF-E 115
              E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP  VF E
Sbjct: 63  ---ESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKE 119

Query: 116 GDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG-YGDEN 174
            D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G +G +N
Sbjct: 120 EDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKN 179



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV  ++SG Y C  
Sbjct: 38  EKDSVTLKCQGAYSPEDNST----QWFHNESLISSQASSY-FIDAATV--DDSGEYRC-- 88

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 89  ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 140

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q   GRK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 141 ----LQNGKGRKYFHH-NSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITI--TQGL 193

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++    G   +  L + LLF
Sbjct: 194 AVSTISSFFPPGYQVSFCLVMVLLF 218


>gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor
           (CD16a) isoform c precursor [Homo sapiens]
          Length = 254

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 58/181 (32%), Positives = 85/181 (46%), Gaps = 11/181 (6%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           +LL  +LL       ++    K V+ + P W    + + VTL C G        T W+H 
Sbjct: 4   LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHN 63

Query: 61  HYWGEKLTLTPGNTL-----EVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF- 114
               E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP  VF 
Sbjct: 64  ----ESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFK 119

Query: 115 EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG-YGDE 173
           E D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G +G +
Sbjct: 120 EEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSK 179

Query: 174 N 174
           N
Sbjct: 180 N 180



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV  ++SG Y C  
Sbjct: 39  EKDSVTLKCQGAYSPEDNST----QWFHNESLISSQASSY-FIDAATV--DDSGEYRC-- 89

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 90  ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 141

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q   GRK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 142 ----LQNGKGRKYFHH-NSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITI--TQGL 194

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++    G   +  L + LLF
Sbjct: 195 AVSTISSFFPPGYQVSFCLVMVLLF 219


>gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor
           (CD16a) isoform c precursor [Homo sapiens]
          Length = 254

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 58/181 (32%), Positives = 85/181 (46%), Gaps = 11/181 (6%)

Query: 1   MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
           +LL  +LL       ++    K V+ + P W    + + VTL C G        T W+H 
Sbjct: 4   LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHN 63

Query: 61  HYWGEKLTLTPGNTL-----EVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVF- 114
               E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP  VF 
Sbjct: 64  ----ESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFK 119

Query: 115 EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG-YGDE 173
           E D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G +G +
Sbjct: 120 EEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSK 179

Query: 174 N 174
           N
Sbjct: 180 N 180



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV  ++SG Y C  
Sbjct: 39  EKDSVTLKCQGAYSPEDNST----QWFHNESLISSQASSY-FIDAATV--DDSGEYRC-- 89

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 90  ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 141

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q   GRK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 142 ----LQNGKGRKYFHH-NSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITI--TQGL 194

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++    G   +  L + LLF
Sbjct: 195 AVSTISSFFPPGYQVSFCLVMVLLF 219


>gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
           isoform a precursor [Homo sapiens]
          Length = 290

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 60/185 (32%), Positives = 86/185 (46%), Gaps = 16/185 (8%)

Query: 2   LLWASLLAFAPVCGQSAAAH-----KPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTT 56
           ++W  LL  A +   SA        K V+ + P W    + + VTL C G        T 
Sbjct: 36  IMWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQ 95

Query: 57  WYHRHYWGEKLTLTPGNT-----LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPY 111
           W+H     E L  +  ++       V +SG YRCQ   S  S+PV+L      L+LQAP 
Sbjct: 96  WFH----NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPR 151

Query: 112 SVF-EGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIG- 169
            VF E D + LRCH  +   L  V Y  NG      + + D  IP+A+  ++G+Y C G 
Sbjct: 152 WVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGL 211

Query: 170 YGDEN 174
           +G +N
Sbjct: 212 FGSKN 216



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 24/205 (11%)

Query: 204 EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGA 263
           E +SV L C+    PE + T     +F +  +I S  S+Y  +   TV  ++SG Y C  
Sbjct: 75  EKDSVTLKCQGAYSPEDNST----QWFHNESLISSQASSY-FIDAATV--DDSGEYRC-- 125

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSW 323
              + N+   S  +Q+ V    +  +LL  Q       E + + L C   + T     ++
Sbjct: 126 ---QTNLSTLSDPVQLEVH---IGWLLL--QAPRWVFKEEDPIHLRCHSWKNTALHKVTY 177

Query: 324 HREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGN 383
               +Q   GRK      ++  +P      +G Y+C        V S  +N+T+  T G 
Sbjct: 178 ----LQNGKGRKYFHH-NSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITI--TQGL 230

Query: 384 RDGLVAAGATGGLLSALLLAVALLF 408
               +++    G   +  L + LLF
Sbjct: 231 AVSTISSFFPPGYQVSFCLVMVLLF 255


>gi|157168355 CD22 molecule [Homo sapiens]
          Length = 847

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 94/412 (22%), Positives = 161/412 (39%), Gaps = 64/412 (15%)

Query: 36  KGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRE-----SGLYRCQA--- 87
           +G +V   C           TWYH    G+++       + + +     +G Y C A   
Sbjct: 345 EGSQVEFLCMSLANPLPTNYTWYHN---GKEMQGRTEEKVHIPKILPWHAGTYSCVAENI 401

Query: 88  -----RGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGN- 141
                RG      V+      + ++Q P  + EGDT+ L C+       +  +Y W  + 
Sbjct: 402 LGTGQRGPGAELDVQYPPKKVTTVIQNPMPIREGDTVTLSCNYNSSNP-SVTRYEWKPHG 460

Query: 142 --------ILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHP 193
                   +L I N  WD      ++ N+                 + ++ KI+ L    
Sbjct: 461 AWEEPSLGVLKIQNVGWDNTTIACAACNSWCSWASPVALNVQYAPRDVRVRKIKPL---- 516

Query: 194 ELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFF--RDGEVILSDWSTYPELQLPTV 251
                 S+   GNSV+L C+       S  P    FF  ++G ++  +     +L   ++
Sbjct: 517 ------SEIHSGNSVSLQCDFS-----SSHPKEVQFFWEKNGRLLGKE----SQLNFDSI 561

Query: 252 WRENSGSYWCGAETVRGNIHKHSPSLQIHV--QRIPVSGVLLETQPSGGQAVEGEMLVLV 309
             E++GSY C      G     + +L++    +R+ VS         G Q +EG+   L 
Sbjct: 562 SPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVS------MSPGDQVMEGKSATLT 615

Query: 310 CSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQ 369
           C        + ++W   + Q SL   +Q+     L L  ++  H+G Y+C   NS G  +
Sbjct: 616 CESDANPPVSHYTWFDWNNQ-SLPYHSQK-----LRLEPVKVQHSGAYWCQGTNSVGKGR 669

Query: 370 SMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVA--LLFHCWRRRKSGVG 419
           S +  +TV  +P      VA G  G  L+ L+LA+    L   W+R +S  G
Sbjct: 670 SPLSTLTVYYSPETIGRRVAVG-LGSCLAILILAICGLKLQRRWKRTQSQQG 720



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 52/200 (26%), Positives = 81/200 (40%), Gaps = 18/200 (9%)

Query: 172 DENDVFRSNFKIIKIQELFPHPELKATDSQPT--EGNSVNLSCETQLPPERSDTPLHFNF 229
           D +  F SN  +    +  P  E+K T S     EG+SV ++CE         T    ++
Sbjct: 223 DADGKFLSNDTVQLNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTT---VSW 279

Query: 230 FRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGV 289
            +DG   L   +T+  L L  V ++ SG Y C      G        LQ+     P +  
Sbjct: 280 LKDG-TSLKKQNTFT-LNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQ 337

Query: 290 LLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAI 349
           +L +      AVEG  +  +C        T ++W+        G++ Q     ++ +P I
Sbjct: 338 ILHS-----PAVEGSQVEFLCMSLANPLPTNYTWYHN------GKEMQGRTEEKVHIPKI 386

Query: 350 RQSHAGGYYCTADNSYGPVQ 369
              HAG Y C A+N  G  Q
Sbjct: 387 LPWHAGTYSCVAENILGTGQ 406



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 20/119 (16%)

Query: 264 ETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGD-TTFS 322
           +TV+ N+ KH+P L+I V             PS     EG+ + + C V+    + TT S
Sbjct: 232 DTVQLNV-KHTPKLEIKVT------------PSDAIVREGDSVTMTCEVSSSNPEYTTVS 278

Query: 323 WHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETP 381
           W ++      G   ++     L L  + +  +G Y C   N  GP +S  + + V+  P
Sbjct: 279 WLKD------GTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAP 331


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 88/347 (25%), Positives = 146/347 (42%), Gaps = 53/347 (15%)

Query: 81  GLYRCQARGS---PRSNPVRL--LFSSDSLILQAPYSVFE-GDTLVLRCHRRRKEKLTAV 134
           G Y C  +       S+PV L  L+  D   +   Y+ +  G  L L CH          
Sbjct: 389 GPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPP---A 445

Query: 135 KYTW--NGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPH 192
           +Y+W  +GNI      + +L I   +  N+G Y C      +   R+  K I +    P 
Sbjct: 446 QYSWLIDGNI---QQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPK 502

Query: 193 PELKATDSQPTEG-NSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLP-- 249
           P + + +S+P E  ++V  +CE    PE  +T   + ++ +G+ +       P LQL   
Sbjct: 503 PSISSNNSKPVEDKDAVAFTCE----PEAQNTT--YLWWVNGQSL----PVSPRLQLSNG 552

Query: 250 -------TVWRENSGSYWCGAE-TVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAV 301
                   V R ++ +Y CG + +V  N    S  + + V   P + ++    P     +
Sbjct: 553 NRTLTLFNVTRNDARAYVCGIQNSVSAN---RSDPVTLDVLYGPDTPII---SPPDSSYL 606

Query: 302 EGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTA 361
            G  L L C  A       +SW    + +   + TQ      L +  I  ++ G Y C  
Sbjct: 607 SGANLNLSCHSASNP-SPQYSWRINGIPQ---QHTQ-----VLFIAKITPNNNGTYACFV 657

Query: 362 DN-SYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALL 407
            N + G   S+V ++TV    G   GL +AGAT G++  +L+ VAL+
Sbjct: 658 SNLATGRNNSIVKSITV-SASGTSPGL-SAGATVGIMIGVLVGVALI 702



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 86/335 (25%), Positives = 138/335 (41%), Gaps = 62/335 (18%)

Query: 68  TLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPY------------SVFE 115
           TLT  N     ++  Y+C+ +     NPV     SDS+IL   Y            S   
Sbjct: 199 TLTLFNVTR-NDTASYKCETQ-----NPVSAR-RSDSVILNVLYGPDAPTISPLNTSYRS 251

Query: 116 GDTLVLRCHRRRKEKLTAVKYTW--NGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDE 173
           G+ L L CH          +Y+W  NG   +    + +L IP  + NN+G+Y C  +  +
Sbjct: 252 GENLNLSCHAASNPP---AQYSWFVNG---TFQQSTQELFIPNITVNNSGSYTCQAHNSD 305

Query: 174 NDVFRSNFKIIKIQELFPHPELKATDSQPTEG-NSVNLSCETQLPPERSDTPLHFNFFRD 232
             + R+    I +    P P + + +S P E  ++V L+CE    PE  +T  +  +  +
Sbjct: 306 TGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCE----PEIQNT-TYLWWVNN 360

Query: 233 GEVILSDWSTYPELQLP---------TVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQR 283
             + +S     P LQL          +V R + G Y CG +        HS  + ++V  
Sbjct: 361 QSLPVS-----PRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS--VDHSDPVILNVLY 413

Query: 284 IPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAE 343
            P    +    PS      G  L L C  A       +SW    +  ++ + TQ     E
Sbjct: 414 GPDDPTI---SPSYTYYRPGVNLSLSCHAASNP-PAQYSWL---IDGNIQQHTQ-----E 461

Query: 344 LELPAIRQSHAGGYYCTADNS-YGPVQSMVLNVTV 377
           L +  I + ++G Y C A+NS  G  ++ V  +TV
Sbjct: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITV 496


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 91/380 (23%), Positives = 148/380 (38%), Gaps = 41/380 (10%)

Query: 40   VTLTCNGFQFYATEKTTWYHRHY---WGEKLTLTPG-NTLEV-----RESGLYRCQARGS 90
            V+L C+    +   + TWY        GE++ L PG +TL++      +SG+Y C+A  +
Sbjct: 1764 VSLPCD-VHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 1822

Query: 91   PRSNP--VRLLFSSDSLILQAPYS------VFEGDTLVLRCHRRRKEKLTAVKYTWNGNI 142
               +   V+L         QAP        V  GD  VL C      + T   Y  +G  
Sbjct: 1823 AGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK-DGQP 1881

Query: 143  LSISNKSWDLL------IPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELK 196
            L ++ ++  L       I +A  ++ G Y C       +  R+    +++   F +P+ +
Sbjct: 1882 LVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE 1941

Query: 197  ATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENS 256
                    G+ + L+C+    P  + T L      +   +    S    LQL  +    +
Sbjct: 1942 TVSQ--VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQA 1999

Query: 257  GSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGT 316
            G+Y C AE  +    K      +   RI  SGV  E        +EG+ + L C  A+G 
Sbjct: 2000 GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVARE-----HHVLEGQEVRLDCE-ADGQ 2053

Query: 317  GDTTFSWHREDMQESLGRKTQRSLR-----AELELPAIRQSHAGGYYCTADNSYGPVQSM 371
                 +W ++     LG+     LR       L L  +R S AG Y C A N  G   + 
Sbjct: 2054 PPPDVAWLKDG--SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE-DAR 2110

Query: 372  VLNVTVRETPGNRDGLVAAG 391
            +  V V   P  + G   +G
Sbjct: 2111 LHTVNVLVPPTIKQGADGSG 2130



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 85/334 (25%), Positives = 146/334 (43%), Gaps = 51/334 (15%)

Query: 75   LEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSV----FEGDTLVLRCH------ 124
            +++ ++G++ C A     ++P  +   + +L +Q P  +    F+ D +V+R        
Sbjct: 2183 VQLADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPC 2237

Query: 125  RRRKEKLTAVKYTWNGN-ILSIS-NKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFK 182
              R   L  V +  +G  +LS S  +   L +    + ++G Y C+   +  +  R +F+
Sbjct: 2238 EARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA-RRHFQ 2296

Query: 183  IIKIQELFPHPELKATDSQPTE-----GNSVNLSCETQLPPERSDTPLHFNFFRDGEVIL 237
            +  ++   PH E      QPTE     G  + L C+ Q  P+ + T     + +DG+ + 
Sbjct: 2297 LTVMEP--PHIE---DSGQPTELSLTPGAPMELLCDAQGTPQPNIT-----WHKDGQALT 2346

Query: 238  SDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIP-VSGVLLETQPS 296
               +     ++  V   ++G Y C AE+  G I K   S ++ VQ  P + G      P 
Sbjct: 2347 RLENNSRATRVLRV--RDAGLYTCLAESPAGAIEK---SFRVRVQAPPNIVG------PR 2395

Query: 297  GGQAVEG---EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAE-LELPAIRQS 352
            G + V G     LVL CSV E       +WHR+ +       TQ   R   L+L A+  +
Sbjct: 2396 GPRFVVGLAPGQLVLECSV-EAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 2454

Query: 353  HAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDG 386
             +G Y CTA N+ G   S+   V +   P  R G
Sbjct: 2455 DSGDYSCTARNAAGST-SVAFRVEIHTVPTIRSG 2487



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 42/141 (29%), Positives = 60/141 (42%), Gaps = 9/141 (6%)

Query: 255  NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
            ++G Y C A    G  HKH   + + VQ  PV    ++  PS  +AV  E ++L C  A 
Sbjct: 2730 HAGRYTCSARNSAGVAHKH---VFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-AS 2781

Query: 315  GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
            G    T +W +E +  + G  TQ     +L +       AG Y C A NS G        
Sbjct: 2782 GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKT-R 2840

Query: 375  VTVRETPGNRDGLVAAGATGG 395
            + V+  P   +GL     T G
Sbjct: 2841 LVVQVPPVIENGLPDLSTTEG 2861



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 78/339 (23%), Positives = 117/339 (34%), Gaps = 52/339 (15%)

Query: 64   GEKLTLTPGNTLEV-----RESGLYRCQARGSPRSNPVRLLFSSDSLILQAP-------- 110
            G    + PG  L +      ++G Y C A+ S  S           L++Q P        
Sbjct: 2800 GVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS-----AMGKTRLVVQVPPVIENGLP 2854

Query: 111  -YSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNK--------SWDLLIPQASSNN 161
              S  EG    L C  R   +      TW+ +   +S          S +LL+      +
Sbjct: 2855 DLSTTEGSHAFLPCKARGSPE---PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQD 2911

Query: 162  NGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERS 221
             G Y C     EN V R+  ++     + P       D     G+ + L C  +  P   
Sbjct: 2912 AGTYTCTA---ENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSP--- 2965

Query: 222  DTPLHFNFFRDGEVI--LSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQI 279
             TP       D  V   +S+      LQ   V RE+SG+Y C AE   G     S    +
Sbjct: 2966 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVS---FV 3021

Query: 280  HVQRIPV---SGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKT 336
            HV+  PV          +P GG       + L C V  G       W ++ +        
Sbjct: 3022 HVKEAPVLQGEAFSYLVEPVGGS------IQLDC-VVRGDPVPDIHWIKDGLPLRGSHLR 3074

Query: 337  QRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNV 375
             +     L +    +  AG Y C A+N  G  + +V+ V
Sbjct: 3075 HQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILV 3113



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 54/238 (22%), Positives = 88/238 (36%), Gaps = 29/238 (12%)

Query: 152  LLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELF----PHPELKATDSQPTEGNS 207
            L I  A   + G Y C+   +  +  ++    + I        P  E+   + +    ++
Sbjct: 1406 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNST 1465

Query: 208  VNLSCETQLPPERSDTPLHFNFFRDGEVIL--SDWSTYPE---LQLPTVWRENSGSYWCG 262
            + L CE+   P     P    +++DG+ +   S      E   LQ+      +SG Y C 
Sbjct: 1466 LTLECESWAVP-----PPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1520

Query: 263  AETVRG------NIHKHSPSLQIHVQRIPVSGVLL--ETQPSGG-----QAVEGEMLVLV 309
            A  V G      N+    P +   V     +  +L  E +  GG     + VE     L 
Sbjct: 1521 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1580

Query: 310  CSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAE-LELPAIRQSHAGGYYCTADNSYG 366
            C           +W+RED   S G +         L++P +R  +AG Y C A N  G
Sbjct: 1581 CDT-NAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 87/387 (22%), Positives = 139/387 (35%), Gaps = 48/387 (12%)

Query: 66   KLTLTPGN-----TLEVRESGLYRCQARGSP----RSNPVRLLFSSDSLILQAPYSVFEG 116
            K T+ P        LE +++G Y C A  +     R   + +L       L    S+  G
Sbjct: 2893 KFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLG 2952

Query: 117  DTLVLRCHRRRKEKLTAVKYTWNGNILS--ISNKSWDLLIPQA--SSNNNGNYRCIGYGD 172
            D L LRC   R      + +T N   ++  +S +     + +A  S  ++G Y C     
Sbjct: 2953 DRLWLRC-AARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA--- 3008

Query: 173  ENDVFRSN-FKIIKIQELFPHPELKATDSQ---PTEGNSVNLSCETQLPPERSDTPLHFN 228
            EN V R+     + ++E    P L+           G S+ L C       R D     +
Sbjct: 3009 ENRVGRTQAVSFVHVKEA---PVLQGEAFSYLVEPVGGSIQLDCVV-----RGDPVPDIH 3060

Query: 229  FFRDGEVILSDWSTYP----ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRI 284
            + +DG  +      +      L +    R+++G Y C AE   G   K    + + +Q  
Sbjct: 3061 WIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKK---VVILVLQSA 3117

Query: 285  PVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAEL 344
            PV     + +P       G+ + L C  A G    T  W +        R+ +      L
Sbjct: 3118 PV----FQVEPQDMTVRSGDDVALRCQ-ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSL 3172

Query: 345  ELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAV 404
             L  +    AG Y C A N  G   +    V   E  G      + G+  G+++     V
Sbjct: 3173 WLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG------SWGSMTGVINGRKFGV 3226

Query: 405  ALL-FHCWRRRKSGVGFLGDETRLPPA 430
            A L     +   SGV  +    R  PA
Sbjct: 3227 ATLNTSVMQEAHSGVSSIHSSIRHVPA 3253



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 29/239 (12%)

Query: 140 GNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATD 199
           G  L +      L I  +   + G Y+C+ +       R         +L  H       
Sbjct: 262 GPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDF-------QLRVHAPPTIWG 314

Query: 200 SQPT------EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTY-----PELQL 248
           S  T      E + V L CE +  P    TP +  +F+DG ++ +           +LQL
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARGVP----TP-NITWFKDGALLPTSTKVVYTRGGRQLQL 369

Query: 249 PTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVL 308
                 ++G Y C A    G   K +  L ++V   P +      +P   +AV G  + L
Sbjct: 370 GRAQSSDAGVYTCKASNAVGAAEK-ATRLDVYV---PPTIEGAGGRPYVVKAVAGRPVAL 425

Query: 309 VCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAE-LELPAIRQSHAGGYYCTADNSYG 366
            C VA G    T SWH E +  +   +++       L L +  ++ +G Y C A +  G
Sbjct: 426 EC-VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG 483



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 62/244 (25%), Positives = 93/244 (38%), Gaps = 37/244 (15%)

Query: 204  EGNSVNLSCETQL--PPE----RSDTPL----HFNFFRDGEVILSDWSTYPELQLPTVWR 253
            E N   L C+T    PP+    R D PL      +  + G V          LQ+P V  
Sbjct: 1573 ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRV----------LQIPLVRA 1622

Query: 254  ENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQ-AVEGEMLVLVCSV 312
            EN+G Y C A    G    H    ++ V   PV  +L +T+    +  V     V +   
Sbjct: 1623 ENAGRYSCKASNEVGEDWLH---YELLVLTPPV--ILGDTEELVEEVTVNASSTVSLQCP 1677

Query: 313  AEGTGDTTFSWHREDMQESLGRKTQRSLRAE-LELPAIRQSHAGGYYCTADNSYGPVQSM 371
            A G    T SW +  +  S   + Q     + L++     + A  Y C A+N  G  + +
Sbjct: 1678 ALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKL 1737

Query: 372  VLNVTVR-ETPGNRDGLVAAGATGGLLSALLLAVALLFH-----CWRRRKSGVGFLGDET 425
                T+R + P    GL     T  L S++ L   +  H      W +    +  LG+E 
Sbjct: 1738 ---FTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALS-LGEEV 1793

Query: 426  RLPP 429
             L P
Sbjct: 1794 FLLP 1797



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 53/237 (22%), Positives = 91/237 (38%), Gaps = 31/237 (13%)

Query: 143  LSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPEL-----KA 197
            L + N+   L + +A + + G Y C+    EN   R+  K  ++  L P PEL       
Sbjct: 1114 LQLQNQGQSLHVERAQAAHTGRYSCVA---ENLAGRAERK-FELSVLVP-PELIGDLDPL 1168

Query: 198  TDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYP-----ELQLPTVW 252
            T+      + + L CE    P     P    +FR  E +     TY       L++    
Sbjct: 1169 TNITAALHSPLTLLCEAMGIP-----PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQ 1223

Query: 253  RENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSV 312
             ++SG Y C A    G   ++       V+ +    +  E      + ++G+   L+C+V
Sbjct: 1224 EQDSGLYSCLASNEAGEARRN-----FSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 1278

Query: 313  AEGTGDTTFSWHREDMQESLGRKTQRSLRAE---LELPAIRQSHAGGYYCTADNSYG 366
              G      +W ++     L R     +  +   L++     S AG Y C A N+ G
Sbjct: 1279 T-GHPQPKLTWFKDG--RPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVG 1332



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 54/245 (22%), Positives = 98/245 (40%), Gaps = 32/245 (13%)

Query: 152  LLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPT----EGNS 207
            L++    +++ G Y C+ +    +    + ++  +  L P    +  D   T     G  
Sbjct: 2084 LVLKGLRASDAGAYTCVAHNPAGE----DARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 2139

Query: 208  VNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTY-----PELQLPTVWRENSGSYWCG 262
            V + C     P R   P+H ++ +DG  +     T        L++  V   ++G + C 
Sbjct: 2140 VTMVC-----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCV 2194

Query: 263  AETVRGNIHKHSPSLQIHVQRI--PVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTT 320
            A +  G +   + +LQ+ V  +  PV     E Q +    V G ++ L C  A G     
Sbjct: 2195 AASPAG-VADRNFTLQVQVPPVLEPV-----EFQ-NDVVVVRGSLVELPCE-ARGVPLPL 2246

Query: 321  FSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRET 380
             SW  +D +  L +  ++     L+L A+    +G Y C A +  G  +     +TV E 
Sbjct: 2247 VSW-MKDGEPLLSQSLEQG--PSLQLEAVGAGDSGTYSCVAVSEAGEARRH-FQLTVMEP 2302

Query: 381  PGNRD 385
            P   D
Sbjct: 2303 PHIED 2307



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 9/131 (6%)

Query: 240 WSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQ 299
           +S  P LQ+  V   + G Y C A  + G   K   +L++    +P +   +E  P    
Sbjct: 653 YSLPPPLQIEKVDLRDEGIYTCAATNLAGE-SKREVALKV---LVPPN---IEPGPVNKA 705

Query: 300 AVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAE-LELPAIRQSHAGGYY 358
            +E   + L C +A G      SW +     S       S+    L +   + S AG Y 
Sbjct: 706 VLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYR 764

Query: 359 CTADNSYGPVQ 369
           C A N  G  +
Sbjct: 765 CVASNVAGSTE 775



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 70/331 (21%), Positives = 129/331 (38%), Gaps = 48/331 (14%)

Query: 75   LEVRESGLYRCQARGSPRSNPV--RLLFSSDSLILQAP--YSVFEGDTLVLRCHRRRKEK 130
            L   +SG Y C AR +  S  V  R+   +   I   P   +V    T +L C   + + 
Sbjct: 2451 LSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPC---QADG 2507

Query: 131  LTAVKYTWNGNILSISNKSWDL-LIPQAS-------SNNNGNYRCIGYGDE-NDVFRSNF 181
            + A   +W  + + +  +S    ++P+ S       + + G+Y C+      +D    + 
Sbjct: 2508 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 2567

Query: 182  KIIKIQELFPHPELKATDSQPTEGNSVNLSCETQ--LPPERSDTPLHFN-FFRDGEVI-- 236
            ++++   + P P            +++ L+  T   LP E S +P     +++DG+ +  
Sbjct: 2568 RVLEPPAIAPSP------------SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDF 2615

Query: 237  ---LSDWSTYPE--LQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLL 291
                  +   P   L L     ++S  + C      G  H+      ++   + V   + 
Sbjct: 2616 RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHR------LYQVTVHVPPTIA 2669

Query: 292  ETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQ-ESLGRKTQRSLRAELELPAIR 350
            + Q      +   + VL C  + G    T SW +   Q  + G   + S    LE+    
Sbjct: 2670 DDQTDFTVTMMAPV-VLTCH-STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQAL 2727

Query: 351  QSHAGGYYCTADNSYGPVQSMVLNVTVRETP 381
              HAG Y C+A NS G     V  +TV+ +P
Sbjct: 2728 PIHAGRYTCSARNSAGVAHKHVF-LTVQASP 2757


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,215,332
Number of Sequences: 37866
Number of extensions: 1080116
Number of successful extensions: 4366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 3351
Number of HSP's gapped (non-prelim): 899
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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