Search of human proteins with 145386549

Search of human proteins with 145386549

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145386549 torsin family 2, member A isoform b [Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145386549 torsin family 2, member A isoform b [Homo sapiens]       535   e-152
gi|197313700 torsin family 2, member A isoform c [Homo sapiens]       419   e-117
gi|145386578 torsin family 2, member A isoform a [Homo sapiens]       412   e-115
gi|4557541 torsin A [Homo sapiens]                                    169   3e-42
gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]       159   2e-39
gi|115647957 torsin family 3, member A [Homo sapiens]                 126   2e-29
gi|197313702 torsin family 2, member A isoform d [Homo sapiens]       108   3e-24
gi|116063568 hypothetical protein LOC54863 [Homo sapiens]              52   4e-07
gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]                33   0.24 
gi|13540606 caseinolytic peptidase B [Homo sapiens]                    31   0.91 
gi|239746778 PREDICTED: hypothetical protein XP_002343847 [Homo ...    29   3.4  
gi|41872646 cullin 7 [Homo sapiens]                                    28   5.9  
gi|4507609 tumor necrosis factor (ligand) superfamily, member 9 ...    28   5.9  

>gi|145386549 torsin family 2, member A isoform b [Homo sapiens]
          Length = 253

 Score =  535 bits (1378), Expect = e-152
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60
           MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL
Sbjct: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60

Query: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120
           AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV
Sbjct: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120

Query: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180
           HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS
Sbjct: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180

Query: 181 SWVVYGTNYRKAIFIFIRWGPALQWAQWGGHFSEVQLYSLSLCSQQNPVPHGLSWAFPVP 240
           SWVVYGTNYRKAIFIFIRWGPALQWAQWGGHFSEVQLYSLSLCSQQNPVPHGLSWAFPVP
Sbjct: 181 SWVVYGTNYRKAIFIFIRWGPALQWAQWGGHFSEVQLYSLSLCSQQNPVPHGLSWAFPVP 240

Query: 241 SATLRDDIVIPPG 253
           SATLRDDIVIPPG
Sbjct: 241 SATLRDDIVIPPG 253


>gi|197313700 torsin family 2, member A isoform c [Homo sapiens]
          Length = 242

 Score =  419 bits (1076), Expect = e-117
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60
           MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL
Sbjct: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60

Query: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120
           AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV
Sbjct: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120

Query: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180
           HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS
Sbjct: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180

Query: 181 SWVVYGTNYRKAIFIFIRW 199
           SWVVYGTNYRKAIFIFIRW
Sbjct: 181 SWVVYGTNYRKAIFIFIRW 199


>gi|145386578 torsin family 2, member A isoform a [Homo sapiens]
          Length = 321

 Score =  412 bits (1060), Expect = e-115
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60
           MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL
Sbjct: 1   MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL 60

Query: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120
           AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV
Sbjct: 61  AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV 120

Query: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180
           HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS
Sbjct: 121 HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS 180

Query: 181 SWVVYGTNYRKAIFIFI 197
           SWVVYGTNYRKAIFIFI
Sbjct: 181 SWVVYGTNYRKAIFIFI 197


>gi|4557541 torsin A [Homo sapiens]
          Length = 332

 Score =  169 bits (427), Expect = 3e-42
 Identities = 76/146 (52%), Positives = 108/146 (73%)

Query: 52  LECDLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLF 111
           L+ DL  +L GQHLAK +++ A+  F+ +P P KPL LSLHGWTGTGK++VS ++A  ++
Sbjct: 61  LQKDLDDNLFGQHLAKKIILNAVFGFINNPKPKKPLTLSLHGWTGTGKNFVSKIIAENIY 120

Query: 112 QGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLM 171
           +GGL S  VH F   LHFPH S+I  YK  L+ W++GN++AC RS+F+FDEMDKM  GL+
Sbjct: 121 EGGLNSDYVHLFVATLHFPHASNITLYKDQLQLWIRGNVSACARSIFIFDEMDKMHAGLI 180

Query: 172 EVLRPFLGSSWVVYGTNYRKAIFIFI 197
           + ++PFL    +V G +Y+KA+FIF+
Sbjct: 181 DAIKPFLDYYDLVDGVSYQKAMFIFL 206


>gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]
          Length = 336

 Score =  159 bits (402), Expect = 2e-39
 Identities = 78/180 (43%), Positives = 109/180 (60%)

Query: 18  LGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAF 77
           +G  SA         + C     C  +   +   L+ DL + L GQHLA  ++ KAL  F
Sbjct: 34  IGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGF 93

Query: 78  VRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIER 137
             +  P KPL LSLHGW GTGK++VS ++A  L   GL+S  VH F   LHFPH   I+ 
Sbjct: 94  RNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKL 153

Query: 138 YKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFI 197
           Y+  L+ W++GN++AC  S+F+FDEMDK+ PG+++ ++PFL     V G +YRKAIFIF+
Sbjct: 154 YQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFL 213


>gi|115647957 torsin family 3, member A [Homo sapiens]
          Length = 397

 Score =  126 bits (317), Expect = 2e-29
 Identities = 58/137 (42%), Positives = 86/137 (62%)

Query: 42  ECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSY 101
           +C    +  GLE DL   L GQHL + LV++ ++ ++  P P K L LS HGW+GTGK++
Sbjct: 116 DCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLETPQPEKALALSFHGWSGTGKNF 175

Query: 102 VSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFD 161
           V+ +L   L++ GL S  V  F    HFPHP +++ YK+ L S ++     C ++LF+FD
Sbjct: 176 VARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQQLCHQTLFIFD 235

Query: 162 EMDKMPPGLMEVLRPFL 178
           E +K+ PGL+EVL P L
Sbjct: 236 EAEKLHPGLLEVLGPHL 252


>gi|197313702 torsin family 2, member A isoform d [Homo sapiens]
          Length = 72

 Score =  108 bits (271), Expect = 3e-24
 Identities = 50/50 (100%), Positives = 50/50 (100%)

Query: 1  MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLP 50
          MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLP
Sbjct: 1  MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLP 50


>gi|116063568 hypothetical protein LOC54863 [Homo sapiens]
          Length = 423

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 4/137 (2%)

Query: 46  RPDLPGLECDLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSL 105
           R DL GLE  L + + GQ  A + +V  ++ ++     ++PL+L+LHG +G GKS+V  L
Sbjct: 147 RYDLDGLEKALQRAVFGQPAAVSRIVALMRDYLATHVHSRPLLLALHGPSGVGKSHVGRL 206

Query: 106 LAHYLFQGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRS----LFLFD 161
           LA +       S  V  +    H P     +  +++L   V   +          L + D
Sbjct: 207 LARHFRSVLEDSALVLQYHARHHCPEARAAQDCREELARRVADVVARAEAEEKTPLLVLD 266

Query: 162 EMDKMPPGLMEVLRPFL 178
           +++ MP  L++ L  FL
Sbjct: 267 DVELMPRPLLDELHGFL 283


>gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]
          Length = 388

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 12/154 (7%)

Query: 83  PTKPLVLSLHGWTGTGK-SYVSSLLAHYLFQGGLRSPRVHHFSPVLH-FPHPSHIE---- 136
           P  P+ L + G  G+GK ++V  L  H   QG    P V +  P +H  P P++I+    
Sbjct: 30  PRHPVCLLVLGMAGSGKTTFVQRLTGHLHAQG--TPPYVINLDPAVHEVPFPANIDIRDT 87

Query: 137 -RYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFI 195
            +YK+ +K +  G       SL LF          +E  +    S +V+  T  +  +F 
Sbjct: 88  VKYKEVMKQYGLGPNGGIVTSLNLFATRFDQVMKFIEKAQNM--SKYVLIDTPGQIEVFT 145

Query: 196 FIRWGPALQWAQWGGHFSEVQLYSLSLCSQQNPV 229
           +   G  +  A     F  V +Y +      NPV
Sbjct: 146 WSASGTIITEA-LASSFPTVVIYVMDTSRSTNPV 178


>gi|13540606 caseinolytic peptidase B [Homo sapiens]
          Length = 707

 Score = 31.2 bits (69), Expect = 0.91
 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 14/133 (10%)

Query: 52  LECDLAQHLAGQHLAKALVVKALKAFVRDPAPTK-PLVLSLHGWTGTGKSYVSSLLAHYL 110
           LE  L +H+ GQ  A A V  A++         + PLV    G +G GK+ ++   A Y+
Sbjct: 339 LEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKYM 398

Query: 111 FQGGLRS---------PRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFD 161
            +   +             H  +  +  P P ++   +      +   L  C  ++ LFD
Sbjct: 399 HKDAKKGFIRLDMSEFQERHEVAKFIGSP-PGYVGHEEG---GQLTKKLKQCPNAVVLFD 454

Query: 162 EMDKMPPGLMEVL 174
           E+DK  P ++ ++
Sbjct: 455 EVDKAHPDVLTIM 467


>gi|239746778 PREDICTED: hypothetical protein XP_002343847 [Homo
           sapiens]
          Length = 215

 Score = 29.3 bits (64), Expect = 3.4
 Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 2/46 (4%)

Query: 17  LLGLVSAAAAAWDLASLRCTLGA-FCECDFRPDLPGLEC-DLAQHL 60
           L GLV+ A   W    LRC  G   C   F P  P   C  L  HL
Sbjct: 156 LAGLVAGAGCRWRALRLRCRHGRHLCRSPFLPASPSTNCFSLLGHL 201


>gi|41872646 cullin 7 [Homo sapiens]
          Length = 1698

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 62   GQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLR 116
            G H+ + LV   L+A+ + P P + LV SL   +    + V S + H L +G LR
Sbjct: 1582 GLHIDQ-LVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLR 1635


>gi|4507609 tumor necrosis factor (ligand) superfamily, member 9
           [Homo sapiens]
          Length = 254

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 16/96 (16%)

Query: 2   AAATRGCR--PWGSLLGLLGLVSAAAAA-------WDLASLRCTLGAFCECDFR------ 46
           A   R CR  PW  + GLL L+  AAA        W ++  R + G+      R      
Sbjct: 18  APRARACRVLPWALVAGLLLLLLLAAACAVFLACPWAVSGARASPGSAASPRLREGPELS 77

Query: 47  PDLPGLECDLAQHLAGQHLAK-ALVVKALKAFVRDP 81
           PD P    DL Q +  Q +A+  L++    ++  DP
Sbjct: 78  PDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDP 113


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,737,145
Number of Sequences: 37866
Number of extensions: 571167
Number of successful extensions: 1422
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1412
Number of HSP's gapped (non-prelim): 13
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.