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Search of human proteins with 14269580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14269580 transmembrane protein 60 [Homo sapiens]
(133 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14269580 transmembrane protein 60 [Homo sapiens] 273 4e-74
gi|22296884 transmembrane protein 185A [Homo sapiens] 44 5e-05
gi|16596686 transmembrane protein 203 [Homo sapiens] 36 0.008
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi... 28 2.2
gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s... 28 2.2
gi|193788730 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788728 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|120433602 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788548 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788542 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788536 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193794832 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788534 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788532 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788530 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788528 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|193788526 calcium channel, voltage-dependent, L type, alpha 1... 27 4.8
gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo s... 26 8.2
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 26 8.2
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 26 8.2
gi|110578657 LOST1 [Homo sapiens] 26 8.2
>gi|14269580 transmembrane protein 60 [Homo sapiens]
Length = 133
Score = 273 bits (697), Expect = 4e-74
Identities = 133/133 (100%), Positives = 133/133 (100%)
Query: 1 MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGR 60
MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGR
Sbjct: 1 MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGR 60
Query: 61 CKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGA 120
CKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGA
Sbjct: 61 CKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGA 120
Query: 121 LTELGYNVFFVRD 133
LTELGYNVFFVRD
Sbjct: 121 LTELGYNVFFVRD 133
>gi|22296884 transmembrane protein 185A [Homo sapiens]
Length = 350
Score = 43.5 bits (101), Expect = 5e-05
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 6/106 (5%)
Query: 17 LLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAG-----RCKSGFDPRHGS 71
+L I + L+LD+ W W ++ +P+WI + L ++++ + R + +
Sbjct: 150 ILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRT 209
Query: 72 HNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALL 117
H +W I + L L F + L KL+ + +F+PLW L
Sbjct: 210 HITMALSWMTIVVPL-LTFEILLVHKLDGHNAFSCIPIFVPLWLSL 254
Score = 41.2 bits (95), Expect = 2e-04
Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 11 LTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGRCKSGFDPRHG 70
L + LLF ++L L+LD W+++ +F P+W++ +++V V ++ G
Sbjct: 16 LIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEG 75
Query: 71 SHNIKKKAWYLIAM---LLKLAFCLALCAKLEQFTTMNLSYVFIPLW 114
++ KA LIA+ LL L F + +C ++E+ + L VF+PL+
Sbjct: 76 ETCVEFKA-MLIAVGIHLLLLMFEVLVCDRIERGSHFWL-LVFMPLF 120
>gi|16596686 transmembrane protein 203 [Homo sapiens]
Length = 136
Score = 36.2 bits (82), Expect = 0.008
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 12/109 (11%)
Query: 14 LFTLLFLIMLVLKLDEKAPW-NWFLIFIPVWIFD---TILLVLLIVKMAGRCKSGFDPRH 69
L L+F ++L L++D P +W+ +F+P + D T ++ V++ F
Sbjct: 24 LALLVFSVLLALRVDGLVPGLSWWNVFVPFFAADGLSTYFTTIVSVRL-------FQDGE 76
Query: 70 GSHNIKKKAWYLIAMLLKLAFCLALCAKL-EQFTTMNLSYVFIPLWALL 117
+ + W L + LK F + LC KL EQ + + PL+ LL
Sbjct: 77 KRLAVLRLFWVLTVLSLKFVFEMLLCQKLAEQTRELWFGLITSPLFILL 125
>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo
sapiens]
Length = 1836
Score = 28.1 bits (61), Expect = 2.2
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 14 LFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMAGRCKSGFDPRHGSH 72
+FT +F +VLKL P+ +F W IFD+I++ L +V++ G
Sbjct: 616 VFTGIFTAEMVLKLIAMDPYEYFQ---QGWNIFDSIIVTLSLVELGLANVQGLSVLRSFR 672
Query: 73 NIK----KKAWYLIAMLLKL 88
++ K+W + ML+K+
Sbjct: 673 LLRVFKLAKSWPTLNMLIKI 692
>gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo
sapiens]
Length = 1977
Score = 28.1 bits (61), Expect = 2.2
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 14 LFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMAGRCKSGFDPRHGSH 72
+FT +F +VLKL P+ +F + W IFD++++ L +V++ G
Sbjct: 771 VFTGIFAAEMVLKLIAMDPYEYFQV---GWNIFDSLIVTLSLVELFLADVEGLSVLRSFR 827
Query: 73 NIK----KKAWYLIAMLLKL 88
++ K+W + ML+K+
Sbjct: 828 LLRVFKLAKSWPTLNMLIKI 847
>gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 4 [Homo sapiens]
Length = 2173
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 3 [Homo sapiens]
Length = 2179
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 18 [Homo sapiens]
Length = 2138
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 20 [Homo sapiens]
Length = 2127
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 17 [Homo sapiens]
Length = 2138
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 14 [Homo sapiens]
Length = 2138
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoforom 13 [Homo sapiens]
Length = 2144
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 12 [Homo sapiens]
Length = 2146
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 11 [Homo sapiens]
Length = 2146
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 9 [Homo sapiens]
Length = 2157
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 8 [Homo sapiens]
Length = 2157
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1253 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1299
>gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C
subunit isoform 6 [Homo sapiens]
Length = 2158
Score = 26.9 bits (58), Expect = 4.8
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 10 LLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVW-IFDTILLVLLIVKMA 58
+L LFT LF + ++LKL P ++ F W FD +++V IV +A
Sbjct: 1273 ILNMLFTGLFTVEMILKLIAFKPKHY---FCDAWNTFDALIVVGSIVDIA 1319
>gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo
sapiens]
Length = 481
Score = 26.2 bits (56), Expect = 8.2
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 3 MSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTIL 49
MSLA LL LF + ++ ++ +A W L+ P W+F +L
Sbjct: 94 MSLAVADLLVGLFVMPIALLTIMF---EAMWPLPLVLCPAWLFLDVL 137
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 26.2 bits (56), Expect = 8.2
Identities = 12/34 (35%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 61 CKSGFDPRHGSHNIKKKAWYLIAMLLKLA--FCL 92
C DPR G ++ W ++A+LL +A FC+
Sbjct: 677 CTHRVDPRIGGGGVQLGKWAILAILLGIALLFCI 710
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 26.2 bits (56), Expect = 8.2
Identities = 12/34 (35%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 61 CKSGFDPRHGSHNIKKKAWYLIAMLLKLA--FCL 92
C DPR G ++ W ++A+LL +A FC+
Sbjct: 677 CTHRVDPRIGGGGVQLGKWAILAILLGIALLFCI 710
>gi|110578657 LOST1 [Homo sapiens]
Length = 177
Score = 26.2 bits (56), Expect = 8.2
Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 28 DEKAPWNWFLI-----FIPVWIFDTILLVLLIVKMAGRCKSGFDPRHGSHNIKKKAWYLI 82
D++AP ++ ++ F PVW + I L++ I+ + + D G+ + + A L
Sbjct: 97 DQEAPRDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVD---GARRLGRLARLLS 153
Query: 83 AMLLKLAFCLALCAKLEQFT 102
L+ + + + A FT
Sbjct: 154 ITLIIMGIVIIMVAVTVNFT 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.335 0.146 0.486
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,217,124
Number of Sequences: 37866
Number of extensions: 145605
Number of successful extensions: 605
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 597
Number of HSP's gapped (non-prelim): 23
length of query: 133
length of database: 18,247,518
effective HSP length: 91
effective length of query: 42
effective length of database: 14,801,712
effective search space: 621671904
effective search space used: 621671904
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.