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Search of human proteins with 14249704
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14249704 RAS-like, estrogen-regulated, growth inhibitor
[Homo sapiens]
(199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 396 e-111
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 152 2e-37
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 149 2e-36
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 147 4e-36
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 147 6e-36
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 147 6e-36
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 142 2e-34
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 142 2e-34
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 136 1e-32
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 134 5e-32
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 134 7e-32
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 133 1e-31
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 133 1e-31
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 132 1e-31
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 132 1e-31
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 132 1e-31
gi|7706095 RAS-like, family 12 protein [Homo sapiens] 132 2e-31
gi|45592963 RAS-like, family 11, member A [Homo sapiens] 131 3e-31
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 131 4e-31
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 129 2e-30
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 129 2e-30
gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 129 2e-30
gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 129 2e-30
gi|169161292 PREDICTED: similar to related RAS viral (r-ras) onc... 129 2e-30
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 128 3e-30
gi|13027612 RAS-like family 11 member B [Homo sapiens] 120 1e-27
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 119 2e-27
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 118 3e-27
gi|21703367 Di-Ras2 [Homo sapiens] 114 4e-26
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 107 7e-24
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 396 bits (1017), Expect = e-111
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MAKSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILD 60
MAKSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILD
Sbjct: 1 MAKSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILD 60
Query: 61 TAGQEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKA 120
TAGQEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKA
Sbjct: 61 TAGQEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKA 120
Query: 121 DLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRR 180
DLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRR
Sbjct: 121 DLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRR 180
Query: 181 SSTTHVKQAINKMLTKISS 199
SSTTHVKQAINKMLTKISS
Sbjct: 181 SSTTHVKQAINKMLTKISS 199
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 152 bits (384), Expect = 2e-37
Identities = 76/163 (46%), Positives = 108/163 (66%), Gaps = 2/163 (1%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDT 67
+L + G GVGKSAL ++F+ F+ +YDPT+E +Y Q IDD ++ILDTAGQE+
Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEF 75
Query: 68 -IQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
RE +MR GEGF+LV+ +TDRGSFEE+ + + +K +IL+GNKADLDH R
Sbjct: 76 GAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQR 135
Query: 127 QVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRR 169
QV+ EEG++LA +L + E SA N+ + F+EL R +R+
Sbjct: 136 QVTQEEGQQLARQLKVTYMEASAKI-RMNVDQAFHELVRVIRK 177
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 149 bits (376), Expect = 2e-36
Identities = 77/168 (45%), Positives = 112/168 (66%), Gaps = 2/168 (1%)
Query: 4 SAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAG 63
S E KL + G GVGKSA+ ++F++ RF ++DPT+E Y+ + IDDE +++ILDTAG
Sbjct: 19 SREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAG 78
Query: 64 Q-EDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADL 122
Q E T R+ +MR GEGF++ Y ITDR SF EV K ++ +++ + ++LVGNK+DL
Sbjct: 79 QAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDL 138
Query: 123 DHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRR 170
RQV+ EEG LA E +C F+E SA I ++F+ L RE+RR+
Sbjct: 139 KQLRQVTKEEGLALAREFSCPFFETSAAY-RYYIDDVFHALVREIRRK 185
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 147 bits (372), Expect = 4e-36
Identities = 79/184 (42%), Positives = 117/184 (63%), Gaps = 6/184 (3%)
Query: 4 SAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAG 63
S E K+ + G GVGKSA+ ++F++ +F +DPT+E Y+ Q ID+E ++ILDTAG
Sbjct: 18 SREYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAG 77
Query: 64 Q-EDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADL 122
Q E T RE +MR GEGF++ Y +TDR SF+E K ++ +++ + L+LVGNK DL
Sbjct: 78 QAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDL 137
Query: 123 DHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRR----MVQGKTR 178
+ RQVSTEEG LA E C F+E SA I + F+ L RE+R++ +++ K +
Sbjct: 138 EQFRQVSTEEGLSLAQEYNCGFFETSAAL-RFCIDDAFHGLVREIRKKESMPSLMEKKLK 196
Query: 179 RRSS 182
R+ S
Sbjct: 197 RKDS 200
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 147 bits (371), Expect = 6e-36
Identities = 80/179 (44%), Positives = 115/179 (64%), Gaps = 3/179 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL V+F+ F+ +YDPT+E +YR Q +D + +EILDTAG E
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
T R+ +M+ G+GF LVY IT + +F ++ L+ + +K +V +ILVGNK DL+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLED 122
Query: 125 SRQVSTEEGEKLATEL-ACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSS 182
R V E+G+ LA + CAF E SA + N+ EIFY+L R++ R+ V GK R++SS
Sbjct: 123 ERVVGKEQGQNLARQWNNCAFLESSA-KSKINVNEIFYDLVRQINRKTPVPGKARKKSS 180
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 147 bits (371), Expect = 6e-36
Identities = 80/179 (44%), Positives = 115/179 (64%), Gaps = 3/179 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL V+F+ F+ +YDPT+E +YR Q +D + +EILDTAG E
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
T R+ +M+ G+GF LVY IT + +F ++ L+ + +K +V +ILVGNK DL+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLED 122
Query: 125 SRQVSTEEGEKLATEL-ACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSS 182
R V E+G+ LA + CAF E SA + N+ EIFY+L R++ R+ V GK R++SS
Sbjct: 123 ERVVGKEQGQNLARQWNNCAFLESSA-KSKINVNEIFYDLVRQINRKTPVPGKARKKSS 180
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 142 bits (357), Expect = 2e-34
Identities = 77/179 (43%), Positives = 114/179 (63%), Gaps = 3/179 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL V+F+ F+ +YDPT+E +YR Q +D + +EILDTAG E
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
T R+ +M+ G+GF LVY IT + +F ++ L+ + +K ++V +ILVGNK DL+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLED 122
Query: 125 SRQVSTEEGEKLATELA-CAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSS 182
R V E+G+ LA + CAF E SA + N+ EIFY+L R++ R+ V+ K ++ S
Sbjct: 123 ERVVGKEQGQNLARQWCNCAFLESSA-KSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 142 bits (357), Expect = 2e-34
Identities = 77/179 (43%), Positives = 114/179 (63%), Gaps = 3/179 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL V+F+ F+ +YDPT+E +YR Q +D + +EILDTAG E
Sbjct: 3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
T R+ +M+ G+GF LVY IT + +F ++ L+ + +K ++V +ILVGNK DL+
Sbjct: 63 QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLED 122
Query: 125 SRQVSTEEGEKLATELA-CAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSS 182
R V E+G+ LA + CAF E SA + N+ EIFY+L R++ R+ V+ K ++ S
Sbjct: 123 ERVVGKEQGQNLARQWCNCAFLESSA-KSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 136 bits (343), Expect = 1e-32
Identities = 75/183 (40%), Positives = 112/183 (61%), Gaps = 6/183 (3%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SFE++ + + +K ++V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP- 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRR---MVQGKTRRRS 181
SR V T++ + LA F E SA T +G + + FY L RE+R+ + GK +++
Sbjct: 122 SRTVDTKQAQDLARSYGIPFIETSAKTRQG-VDDAFYTLVREIRKHKEKMSKDGKKKKKK 180
Query: 182 STT 184
S T
Sbjct: 181 SKT 183
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 134 bits (337), Expect = 5e-32
Identities = 72/187 (38%), Positives = 113/187 (60%), Gaps = 7/187 (3%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQED- 66
K+ + G GVGKSAL ++F+ F+ +Y+PT +YR + +D E V ++ILDTAGQED
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 67 TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
R+ + R GEGF+ V+ IT+ SF + + +K+ +NV +LVGNK+DL+ R
Sbjct: 76 AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKR 135
Query: 127 QVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM-----VQGKTRRRS 181
QVS EE + A + + E SA T N+ ++F++L RE+R R+M GK +R+S
Sbjct: 136 QVSVEEAKNRAEQWNVNYVETSAKT-RANVDKVFFDLMREIRARKMEDSKEKNGKKKRKS 194
Query: 182 STTHVKQ 188
+++
Sbjct: 195 LAKRIRE 201
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 134 bits (336), Expect = 7e-32
Identities = 68/163 (41%), Positives = 108/163 (66%), Gaps = 2/163 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E K+ + G GVGKSAL V+F+T FI +YDPT+E YR + +D +EILDTAG E
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
R+ +++ G+GF+LVY + ++ SF+++ P+++ + +K+ + V +ILVGNK DL+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEG 122
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREV 167
R+VS EG+ LA E +C F E SA + ++ E+F E+ R++
Sbjct: 123 EREVSYGEGKALAEEWSCPFMETSA-KNKASVDELFAEIVRQM 164
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 133 bits (334), Expect = 1e-31
Identities = 74/187 (39%), Positives = 112/187 (59%), Gaps = 4/187 (2%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SFE++ + + +K ++V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP- 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQ-GKTRRRSST 183
SR V T++ + LA F E SA T + + + FY L RE+R+ R+ + K +
Sbjct: 122 SRTVDTKQAQDLARSYGIPFIETSAKTRQ-RVEDAFYTLVREIRQYRLKKISKEEKTPGC 180
Query: 184 THVKQAI 190
+K+ I
Sbjct: 181 VKIKKCI 187
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 133 bits (334), Expect = 1e-31
Identities = 68/163 (41%), Positives = 106/163 (65%), Gaps = 2/163 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E K+ + G GVGKSAL V+F+T FI +YDPT+E YR + +D +EILDTAG E
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
R+ +++ G+GF+LVY + ++ SF+++ P+++ + +K+ + V +ILVGNK DL+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLES 122
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREV 167
R+VS+ EG LA E C F E SA + + E+F E+ R++
Sbjct: 123 EREVSSSEGRALAEEWGCPFMETSA-KSKTMVDELFAEIVRQM 164
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 132 bits (333), Expect = 1e-31
Identities = 67/178 (37%), Positives = 114/178 (64%), Gaps = 3/178 (1%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQED- 66
KL + G GVGKSAL ++F K F+ +YDPT+E +Y ID++ +++LDTAGQE+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 67 TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
+ RE +MR G+GF++VY +TD+ SFE V ++ +K ++ +ILV NK DL H R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 127 QVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSSTT 184
+++ E+G+++AT+ + E SA N+ + F++L R +R++ + K++++ T
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQ--IPEKSQKKKKKT 190
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 132 bits (333), Expect = 1e-31
Identities = 67/178 (37%), Positives = 114/178 (64%), Gaps = 3/178 (1%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQED- 66
KL + G GVGKSAL ++F K F+ +YDPT+E +Y ID++ +++LDTAGQE+
Sbjct: 15 KLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEF 74
Query: 67 TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
+ RE +MR G+GF++VY +TD+ SFE V ++ +K ++ +ILV NK DL H R
Sbjct: 75 SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLR 134
Query: 127 QVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSSTT 184
+++ E+G+++AT+ + E SA N+ + F++L R +R++ + K++++ T
Sbjct: 135 KITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQ--IPEKSQKKKKKT 190
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 132 bits (333), Expect = 1e-31
Identities = 68/163 (41%), Positives = 105/163 (64%), Gaps = 2/163 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E K+ + G GVGKSAL V+F+T FI +YDPT+E YR + +D +EILDTAG E
Sbjct: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
R+ +++ G+GF+LVY + ++ SF+++ P+++ + +K+ + V LILVGNK DL+
Sbjct: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEP 122
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREV 167
R+V + EG LA E C F E SA + + E+F E+ R++
Sbjct: 123 EREVMSSEGRALAQEWGCPFMETSA-KSKSMVDELFAEIVRQM 164
>gi|7706095 RAS-like, family 12 protein [Homo sapiens]
Length = 266
Score = 132 bits (332), Expect = 2e-31
Identities = 69/166 (41%), Positives = 96/166 (57%), Gaps = 2/166 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
EV LAI GR G GKSAL V+FLTKRFI EYDP LE TY + T+D + V + ++DTA +
Sbjct: 20 EVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLD 79
Query: 66 DTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKK--PKNVTLILVGNKADLD 123
E ++ W F++VY + R SF+ +L K +++ +L+GNK D+
Sbjct: 80 TPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMA 139
Query: 124 HSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRR 169
RQV+ EG LA C F+E SAC ++ +F+E RE RR
Sbjct: 140 QYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARR 185
>gi|45592963 RAS-like, family 11, member A [Homo sapiens]
Length = 242
Score = 131 bits (330), Expect = 3e-31
Identities = 69/184 (37%), Positives = 108/184 (58%), Gaps = 8/184 (4%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQ- 64
++KLA+ G VGKSA++VRFLTKRFI +Y+P Y ++ + +S++I DT G
Sbjct: 27 DIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGV 86
Query: 65 --EDTIQR-----EGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVG 117
+D++ + ++W EGF+LVY ITD S+ + PL + ++ +I+VG
Sbjct: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVG 146
Query: 118 NKADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKT 177
NK DL H+RQV T++G +LA EL F E S ++ ++F LC+EV + + G+
Sbjct: 147 NKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGER 206
Query: 178 RRRS 181
RR S
Sbjct: 207 RRAS 210
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 131 bits (329), Expect = 4e-31
Identities = 71/168 (42%), Positives = 104/168 (61%), Gaps = 3/168 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SF ++ + + +K +V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLP- 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM 172
+R V T++ +LA F E SA T +G + + FY L RE+R+ RM
Sbjct: 122 TRTVDTKQAHELAKSYGIPFIETSAKTRQG-VEDAFYTLVREIRQYRM 168
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 129 bits (324), Expect = 2e-30
Identities = 68/168 (40%), Positives = 104/168 (61%), Gaps = 3/168 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SFE++ + + +K +V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-A 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM 172
+R V + + + LA + E SA T +G + + FY L RE+R+ ++
Sbjct: 122 ARTVESRQAQDLARSYGIPYIETSAKTRQG-VEDAFYTLVREIRQHKL 168
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 129 bits (324), Expect = 2e-30
Identities = 68/168 (40%), Positives = 104/168 (61%), Gaps = 3/168 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SFE++ + + +K +V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-A 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM 172
+R V + + + LA + E SA T +G + + FY L RE+R+ ++
Sbjct: 122 ARTVESRQAQDLARSYGIPYIETSAKTRQG-VEDAFYTLVREIRQHKL 168
>gi|169160721 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 2e-30
Identities = 66/140 (47%), Positives = 91/140 (65%), Gaps = 2/140 (1%)
Query: 31 FIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDT-IQREGHMRWGEGFVLVYDITDR 89
F+ +YDPT E +Y Q IDD ++ILDTAGQE+ RE +MR GEGF+LV+ +TDR
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 90 GSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSRQVSTEEGEKLATELACAFYECSA 149
GSFEE+ + + +K +IL+GNKADLDH RQV+ EEG +LA +L + E SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 150 CTGEGNITEIFYELCREVRR 169
N+ + F+EL R +R+
Sbjct: 140 KI-RMNVDQAFHELVRVIRK 158
>gi|169161589 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 2e-30
Identities = 66/140 (47%), Positives = 91/140 (65%), Gaps = 2/140 (1%)
Query: 31 FIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDT-IQREGHMRWGEGFVLVYDITDR 89
F+ +YDPT E +Y Q IDD ++ILDTAGQE+ RE +MR GEGF+LV+ +TDR
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 90 GSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSRQVSTEEGEKLATELACAFYECSA 149
GSFEE+ + + +K +IL+GNKADLDH RQV+ EEG +LA +L + E SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 150 CTGEGNITEIFYELCREVRR 169
N+ + F+EL R +R+
Sbjct: 140 KI-RMNVDQAFHELVRVIRK 158
>gi|169161292 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 2e-30
Identities = 66/140 (47%), Positives = 91/140 (65%), Gaps = 2/140 (1%)
Query: 31 FIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDT-IQREGHMRWGEGFVLVYDITDR 89
F+ +YDPT E +Y Q IDD ++ILDTAGQE+ RE +MR GEGF+LV+ +TDR
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 90 GSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSRQVSTEEGEKLATELACAFYECSA 149
GSFEE+ + + +K +IL+GNKADLDH RQV+ EEG +LA +L + E SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 150 CTGEGNITEIFYELCREVRR 169
N+ + F+EL R +R+
Sbjct: 140 KI-RMNVDQAFHELVRVIRK 158
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 128 bits (322), Expect = 3e-30
Identities = 68/187 (36%), Positives = 112/187 (59%), Gaps = 3/187 (1%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQED- 66
K+ + G GVGKSAL ++F+ F+ +Y+PT +YR + +D E V ++ILDTAGQED
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
Query: 67 TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKN-VTLILVGNKADLDHS 125
R+ + R GEGF+LV+ IT+ SF + + +K ++ + L++VGNK+DL+
Sbjct: 76 AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEER 135
Query: 126 RQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRRSSTTH 185
RQV EE A E + E SA T N+ ++F++L RE+R ++M + K + ++
Sbjct: 136 RQVPVEEARSKAEEWGVQYVETSAKT-RANVDKVFFDLMREIRTKKMSENKDKNGKKSSK 194
Query: 186 VKQAINK 192
K++ +
Sbjct: 195 NKKSFKE 201
>gi|13027612 RAS-like family 11 member B [Homo sapiens]
Length = 248
Score = 120 bits (300), Expect = 1e-27
Identities = 64/184 (34%), Positives = 107/184 (58%), Gaps = 7/184 (3%)
Query: 7 VKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAG--- 63
VK+A+ G +GVGK+ALVVRFLTKRFI +Y+ + Y Q I+ E +++++ DT G
Sbjct: 34 VKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIEGETLALQVQDTPGIQV 93
Query: 64 QEDTI----QREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNK 119
E+++ Q +RW + V+V+ ITD S+E + L + ++ + +++V NK
Sbjct: 94 HENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQLHQHVQQLHLGTRLPVVVVANK 153
Query: 120 ADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRR 179
ADL H +QV + G +LA+ L C+FYE S ++ F+ LC+EV ++ +
Sbjct: 154 ADLLHIKQVDPQLGLQLASMLGCSFYEVSVSENYNDVYSAFHVLCKEVSHKQQPSSTPEK 213
Query: 180 RSST 183
R ++
Sbjct: 214 RRTS 217
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 119 bits (297), Expect = 2e-27
Identities = 68/163 (41%), Positives = 95/163 (58%), Gaps = 2/163 (1%)
Query: 8 KLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDT 67
KL + G GVGKSAL ++F+ F+ +YDPT+E +Y ++D ++ILDTAGQE+
Sbjct: 31 KLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEF 90
Query: 68 -IQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSR 126
RE +MR G GF+LV+ I DR SF EV L + +K + ++LVGNKADL+ R
Sbjct: 91 GAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQR 150
Query: 127 QVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRR 169
QV E A++E SA N+ E F +L R VR+
Sbjct: 151 QVPRSEASAFGASHHVAYFEASAKL-RLNVDEAFEQLVRAVRK 192
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 118 bits (296), Expect = 3e-27
Identities = 62/151 (41%), Positives = 93/151 (61%), Gaps = 2/151 (1%)
Query: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
E KL + G GVGKSAL ++ + F+ EYDPT+E +YR Q ID E ++ILDTAGQE
Sbjct: 3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQE 62
Query: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
+ + R+ +MR GEGF+ V+ I + SFE++ + + +K +V ++LVGNK DL
Sbjct: 63 EYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-A 121
Query: 125 SRQVSTEEGEKLATELACAFYECSACTGEGN 155
+R V + + + LA + E SA T +G+
Sbjct: 122 ARTVESRQAQDLARSYGIPYIETSAKTRQGS 152
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 114 bits (286), Expect = 4e-26
Identities = 72/184 (39%), Positives = 106/184 (57%), Gaps = 8/184 (4%)
Query: 3 KSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTA 62
+S + ++A+FG GVGKS+LV+RF+ F Y PT+E TYR + D + +++I DT
Sbjct: 4 QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTT 63
Query: 63 G--QEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIK-KPKNVTLILVGNK 119
G Q +QR + G F+LVY IT R S EE+ P+ + EIK +++ ++LVGNK
Sbjct: 64 GSHQFPAMQRLSISK-GHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNK 122
Query: 120 ADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM---VQGK 176
D SR+V + E E LA CAF E SA N+ E+F EL +RR + + GK
Sbjct: 123 CDESPSREVQSSEAEALARTWKCAFMETSAKLNH-NVKELFQELLNLEKRRTVSLQIDGK 181
Query: 177 TRRR 180
++
Sbjct: 182 KSKQ 185
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 107 bits (267), Expect = 7e-24
Identities = 69/188 (36%), Positives = 106/188 (56%), Gaps = 9/188 (4%)
Query: 3 KSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTA 62
+S + ++ +FG GVGKS+LV+RF+ F Y PT+E TYR + D V +++I DT
Sbjct: 4 QSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTT 63
Query: 63 G--QEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIK-KPKNVTLILVGNK 119
G Q +QR + G F+LV+ +T + S EE+ P+ ++ +IK +++ ++LVGNK
Sbjct: 64 GSHQFPAMQRLSISK-GHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNK 122
Query: 120 ADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRM---VQGK 176
D + R+V T E + +A E CAF E SA N+ E+F EL RR M + GK
Sbjct: 123 CD-ETQREVDTREAQAVAQEWKCAFMETSAKMNY-NVKELFQELLTLETRRNMSLNIDGK 180
Query: 177 TRRRSSTT 184
+ T
Sbjct: 181 RSGKQKRT 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,505,733
Number of Sequences: 37866
Number of extensions: 264195
Number of successful extensions: 1098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 688
Number of HSP's gapped (non-prelim): 215
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.