Search of human proteins with 14249538

Search of human proteins with 14249538

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249538 ORAI calcium release-activated calcium modulator 2
[Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187607422 ORAI calcium release-activated calcium modulator 2 ...   513   e-146
gi|14249538 ORAI calcium release-activated calcium modulator 2 [...   513   e-146
gi|38016943 calcium release-activated calcium channel protein 1 ...   313   7e-86
gi|22748651 ORAI calcium release-activated calcium modulator 3 [...   296   9e-81
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    32   0.70 
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]         30   1.6  
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom...    30   2.7  
gi|20544172 bradykinin receptor B1 [Homo sapiens]                      30   2.7  
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom...    29   3.5  
gi|169215927 PREDICTED: hypothetical protein [Homo sapiens]            28   5.9  
gi|239752137 PREDICTED: hypothetical protein [Homo sapiens]            28   5.9  
gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo sap...    28   5.9  
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              28   5.9  
gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]              28   5.9  
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]    28   5.9  
gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]            28   7.7  

>gi|187607422 ORAI calcium release-activated calcium modulator 2
           [Homo sapiens]
          Length = 254

 Score =  513 bits (1322), Expect = e-146
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL 60
           MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL
Sbjct: 1   MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL 60

Query: 61  KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP 120
           KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP
Sbjct: 61  KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP 120

Query: 121 NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR 180
           NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR
Sbjct: 121 NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR 180

Query: 181 QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL 240
           QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL
Sbjct: 181 QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL 240

Query: 241 KVQLDGHERSLQVL 254
           KVQLDGHERSLQVL
Sbjct: 241 KVQLDGHERSLQVL 254


>gi|14249538 ORAI calcium release-activated calcium modulator 2
           [Homo sapiens]
          Length = 254

 Score =  513 bits (1322), Expect = e-146
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL 60
           MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL
Sbjct: 1   MSAELNVPIDPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKL 60

Query: 61  KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP 120
           KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP
Sbjct: 61  KASSRTSALLSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILP 120

Query: 121 NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR 180
           NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR
Sbjct: 121 NVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARR 180

Query: 181 QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL 240
           QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL
Sbjct: 181 QPGPPPGPGSHTGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKL 240

Query: 241 KVQLDGHERSLQVL 254
           KVQLDGHERSLQVL
Sbjct: 241 KVQLDGHERSLQVL 254


>gi|38016943 calcium release-activated calcium channel protein 1
           [Homo sapiens]
          Length = 301

 Score =  313 bits (803), Expect = 7e-86
 Identities = 164/254 (64%), Positives = 192/254 (75%), Gaps = 20/254 (7%)

Query: 10  DPSAPACPEPGHKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSAL 69
           D   P  P P    + Y DW+ +SY E+++ N HS+QALSWRKLYLSRAKLKASSRTSAL
Sbjct: 36  DGEPPGAPPPPPSAVTYPDWIGQSYSEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSAL 95

Query: 70  LSGFAMVAMVEVQLETQYQYPRPLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIH 129
           LSGFAMVAMVEVQL+  + YP  LLIAFSACTTVLVAVHLFAL+ISTCILPN+EAVSN+H
Sbjct: 96  LSGFAMVAMVEVQLDADHDYPPGLLIAFSACTTVLVAVHLFALMISTCILPNIEAVSNVH 155

Query: 130 NLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARRQPG------ 183
           NLNS+ ESPHERMH +IELAW FSTV+G LLFLAEVVLLCW+KFLP+  ++QPG      
Sbjct: 156 NLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPL--KKQPGQPRPTS 213

Query: 184 PPPGPGSHT---------GWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREI 234
            PP  G+           G  AA+ ST IMVP GLIF+VF +HFYRSLV HKT+R  +E+
Sbjct: 214 KPPASGAAANVSTSGITPGQAAAIASTTIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQEL 273

Query: 235 EEL---HKLKVQLD 245
            EL    +L+ QLD
Sbjct: 274 NELAEFARLQDQLD 287


>gi|22748651 ORAI calcium release-activated calcium modulator 3
           [Homo sapiens]
          Length = 295

 Score =  296 bits (759), Expect = 9e-81
 Identities = 152/266 (57%), Positives = 193/266 (72%), Gaps = 47/266 (17%)

Query: 26  YRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLET 85
           YR++V R YL+L+ ++ HS++ALSWR+LYLSRAKLKASSRTSALLSGFAMVAMVEVQLE+
Sbjct: 27  YREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLES 86

Query: 86  QYQYPRPLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPY 145
            ++YP  LL+AFSACTTVLVAVHLFAL++STC+LP++EAVSNIHNLNS+ +SPH+R+H Y
Sbjct: 87  DHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRY 146

Query: 146 IELAWGFSTVLGILLFLAEVVLLCWIKFLPVDA--------------------------- 178
           +ELAWGFST LG  LFLAEVVL+ W+KF+P+ A                           
Sbjct: 147 VELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLDTPTPMVPTSRVPGTLAPVATSLSP 206

Query: 179 --------------RRQPGPPP-----GPGSH-TGWQAALVSTIIMVPVGLIFVVFTIHF 218
                         + +P  PP     G G+H  GWQAA+ ST IMVPVGL+FV F +HF
Sbjct: 207 ASNLPRSSASAAPSQAEPACPPRQACGGGGAHGPGWQAAMASTAIMVPVGLVFVAFALHF 266

Query: 219 YRSLVRHKTERHNREIEELHKLKVQL 244
           YRSLV HKT+R+ +E+EEL++L+ +L
Sbjct: 267 YRSLVAHKTDRYKQELEELNRLQGEL 292


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
           sapiens]
          Length = 349

 Score = 31.6 bits (70), Expect = 0.70
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 207 VGLIFVVFTIHFYRSLVRHKTER--HNREIEELHKLKVQLDGHE 248
           +GL+ VV +  FY  L RH +ER   NR  EE H+ +   D  E
Sbjct: 203 MGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEE 246


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 141 RMHPYIELAWGFSTVLGILLFLAEVVLLCW--IKFLPVDARRQPGPPPGPGSHTGWQAAL 198
           R  PY  L W   + L + +F+A ++LL W  +++   + + +  P      + GW  A 
Sbjct: 511 RPSPYWRLTWRVVSPLLLTIFVAYIILLFWKPLRYKAWNPKYELFPSRQEKLYPGWARAA 570

Query: 199 VSTIIMVPV 207
              + ++PV
Sbjct: 571 CVLLSLLPV 579


>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
           sapiens]
          Length = 358

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 17/61 (27%), Positives = 28/61 (45%)

Query: 103 VLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFL 162
           VLV   +F  L+ TC++  V   S   N   ++ +P  R   Y   A  F ++  +L+  
Sbjct: 69  VLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLF 128

Query: 163 A 163
           A
Sbjct: 129 A 129


>gi|20544172 bradykinin receptor B1 [Homo sapiens]
          Length = 353

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 101 TTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMH--PYIELAWGFSTVLGI 158
           T VL+ V    L I T +L +++AV +++    I   PHE  H    +EL      +LG 
Sbjct: 157 TCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVEL-----NILGF 211

Query: 159 LLFLAEVVLLCWIKFLPVDARRQPGPPPGPGSHTGWQAALVSTIIM 204
           LL LA +V   +     +  R +       G       AL+ T+++
Sbjct: 212 LLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVV 257


>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
           sapiens]
          Length = 1352

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 140 ERMHPY-IELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARRQPGPP-PGPGSHTGWQAA 197
           E+  PY +E  +G+   L  L ++ ++     IK L +  RR+P  P P P + +G Q  
Sbjct: 26  EQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKRLNIQKRRKPSVPCPEPRTTSGQQGI 85

Query: 198 LVST 201
             ST
Sbjct: 86  WTST 89


>gi|169215927 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 357

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 220 RSLVRHKTERHNREIEELHKLKVQLDGHERSLQ 252
           R   R + ER  R +EE  + K  L+ H R LQ
Sbjct: 116 REAARERAERVRRRLEEAERHKEDLEQHSRQLQ 148


>gi|239752137 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 357

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 220 RSLVRHKTERHNREIEELHKLKVQLDGHERSLQ 252
           R   R + ER  R +EE  + K  L+ H R LQ
Sbjct: 116 REAARERAERVRRRLEEAERHKEDLEQHSRQLQ 148


>gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 356

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 220 RSLVRHKTERHNREIEELHKLKVQLDGHERSLQ 252
           R   R + ER  R +EE  + K  L+ H R LQ
Sbjct: 116 REAARERAERVRRRLEEAERHKEDLEQHSRQLQ 148


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 10/19 (52%), Positives = 13/19 (68%)

Query: 175 PVDARRQPGPPPGPGSHTG 193
           P +  RQPGP P PG ++G
Sbjct: 888 PQEGTRQPGPTPSPGPNSG 906


>gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]
          Length = 827

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 141 RMHPYIELAWGFSTVLGILLFL-AEVVLLCWIKFLPVDARRQPGPPPGPG 189
           R+HP  EL     TVL +L  L  E  +L    + P       GP PGPG
Sbjct: 178 RLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPG 227


>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
          Length = 1603

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 1/34 (2%)

Query: 175  PVDARRQPGPPPGP-GSHTGWQAALVSTIIMVPV 207
            P++  R PGPP GP  +  G+   L+S + + PV
Sbjct: 1518 PLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPV 1551


>gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 357

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 220 RSLVRHKTERHNREIEELHKLKVQLDGHERSLQ 252
           R   R + ER  R +EE  + K  L+ H R LQ
Sbjct: 116 REAARERAERVRRRLEEAERHKEYLEQHSRQLQ 148


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,430,971
Number of Sequences: 37866
Number of extensions: 456203
Number of successful extensions: 2944
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2930
Number of HSP's gapped (non-prelim): 19
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.