Search of human proteins with 9966881

Search of human proteins with 9966881

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966881 nucleoporin 107kDa [Homo sapiens]
         (925 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966881 nucleoporin 107kDa [Homo sapiens]                         1852   0.0  
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]                34   0.55 
gi|27901803 protein serine kinase H1 [Homo sapiens]                    34   0.55 
gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Ho...    33   0.94 
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...    33   1.6  
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ...    32   2.1  
gi|19743886 regulatory factor X4 isoform a [Homo sapiens]              30   7.9  
gi|15011898 regulatory factor X4 isoform b [Homo sapiens]              30   7.9  
gi|47132527 regulatory factor X4 isoform c [Homo sapiens]              30   7.9  

>gi|9966881 nucleoporin 107kDa [Homo sapiens]
          Length = 925

 Score = 1852 bits (4796), Expect = 0.0
 Identities = 925/925 (100%), Positives = 925/925 (100%)

Query: 1   MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60
           MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR
Sbjct: 1   MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFR 60

Query: 61  QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120
           QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG
Sbjct: 61  QPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSG 120

Query: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180
           LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI
Sbjct: 121 LFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENI 180

Query: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240
           CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF
Sbjct: 181 CGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVF 240

Query: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300
           AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT
Sbjct: 241 AVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENT 300

Query: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360
           LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE
Sbjct: 301 LHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTE 360

Query: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420
           EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF
Sbjct: 361 EAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELF 420

Query: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480
           NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR
Sbjct: 421 NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPR 480

Query: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540
           EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN
Sbjct: 481 EYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540

Query: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600
           NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL
Sbjct: 541 NLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDL 600

Query: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660
           AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL
Sbjct: 601 AVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPAL 660

Query: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720
           DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI
Sbjct: 661 DTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSI 720

Query: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780
           AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP
Sbjct: 721 AEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQP 780

Query: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840
           TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH
Sbjct: 781 TFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDH 840

Query: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900
           ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL
Sbjct: 841 ERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKL 900

Query: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925
           LQKLRESSLMLLDQGLDPLGYEIQL
Sbjct: 901 LQKLRESSLMLLDQGLDPLGYEIQL 925


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 34.3 bits (77), Expect = 0.55
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)

Query: 424  ERAIYAALSGNLKQLLPVCDTWEDTV-------WAYFRVMVDSLVEQEIQTSVATLDETE 476
            ER ++  L+ N+  LL   D+   TV       W +F +++ S+ +  I T+   L   +
Sbjct: 960  ERTVHEELAKNVTGLLKSNDS--TTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQ 1017

Query: 477  ELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFL 519
              P  Y      L  V  +      K  LEE +   H V +FL
Sbjct: 1018 RFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFL 1060


>gi|27901803 protein serine kinase H1 [Homo sapiens]
          Length = 424

 Score = 34.3 bits (77), Expect = 0.55
 Identities = 39/186 (20%), Positives = 73/186 (39%), Gaps = 12/186 (6%)

Query: 562 LQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHC 621
           ++TK     EV ++ +++L R +H N+I        Q+    +  + +E  T  E     
Sbjct: 129 IETKYREGREVCESELRVLRRVRHANIIQLVEVFETQE----RVYMVMELATGGELFDRI 184

Query: 622 LELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFD 681
           +      + D   + + V++ +R       +H DL P            KI + D+ +  
Sbjct: 185 IAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGL-- 242

Query: 682 PAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIY--NQCEEQGMESPLPAE 739
               A A K+G+  + K         A EV V+ P  +  +++         +   +P E
Sbjct: 243 ----ASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298

Query: 740 DDNAIR 745
           DDN  R
Sbjct: 299 DDNRTR 304


>gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Homo
           sapiens]
          Length = 569

 Score = 33.5 bits (75), Expect = 0.94
 Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 18/180 (10%)

Query: 224 SLYRDRIQSALEE-ESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIG 282
           S  R  +  AL E E++ AV  V+ S K    A  QR     Q Q  V  L++I KD I 
Sbjct: 41  SRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQR-----QCQEEVASLQAILKDSIS 95

Query: 283 EFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDRED 342
            +   I    +    +      K+R+L    G ++ L++   P   + ++M   +   ED
Sbjct: 96  SYEAQITALKQERQQQQQDCEEKEREL----GRLKQLLSRAYPLDSLEKQM---EKAHED 148

Query: 343 EVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNP 402
             +L + +       M +E + L  +  +A         +  H P+++G TEL P+  +P
Sbjct: 149 SEKLREIVLP-----MEKEIEELKAKLLRAEELIQEIQRRPRHAPSLHGSTELLPLSRDP 203


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 31/155 (20%)

Query: 800  GIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPM--- 856
            G+ K  +    A+    + +V+  +D G M + R DA +  E      + +   L     
Sbjct: 905  GVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGR 964

Query: 857  -------LCFLLHTILHSTGQY--------------QECLQLADMVSSERHKLYLVFSK- 894
                   +CF L T  H   Q               Q CL++  +     H L  VFS+ 
Sbjct: 965  AGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRL 1024

Query: 895  ------EELRKLLQKLRESSLMLLDQGLDPLGYEI 923
                  + LR    +LR+   +  D+ L PLGY +
Sbjct: 1025 IEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHL 1059


>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
           sapiens]
          Length = 473

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 565 KEEVSIEVLKTYIQLLIREKHTNLIAFYTC-HLPQDLAVAQYALFLESVTEFEQRHHCLE 623
           K+ V  ++++T I +L+R  H N+I        P ++     +L LE VT  E     +E
Sbjct: 78  KKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEI-----SLVLELVTGGELFDRIVE 132

Query: 624 LAKEADLDVATITKTVVENIRKKDNGEFSHHDLAP 658
               ++ D A   K ++E +         H DL P
Sbjct: 133 KGYYSERDAADAVKQILEAVAYLHENGIVHRDLKP 167


>gi|19743886 regulatory factor X4 isoform a [Homo sapiens]
          Length = 641

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHS---TGQYQECLQLADMVSSERHKLY-LVF 892
           K +  R    +L R+  L  LC    T++HS   T Q  E  +  D+ S  +  LY +  
Sbjct: 215 KFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMED 274

Query: 893 SKEELRKLLQKLRESSLMLLDQ 914
           S++E RKL+ +L +    LL++
Sbjct: 275 SRDEHRKLITQLYQEFDHLLEE 296


>gi|15011898 regulatory factor X4 isoform b [Homo sapiens]
          Length = 563

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHS---TGQYQECLQLADMVSSERHKLY-LVF 892
           K +  R    +L R+  L  LC    T++HS   T Q  E  +  D+ S  +  LY +  
Sbjct: 318 KFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMED 377

Query: 893 SKEELRKLLQKLRESSLMLLDQ 914
           S++E RKL+ +L +    LL++
Sbjct: 378 SRDEHRKLITQLYQEFDHLLEE 399


>gi|47132527 regulatory factor X4 isoform c [Homo sapiens]
          Length = 735

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 837 KEDHERTHQMVLLRKLCLPMLCFLLHTILHS---TGQYQECLQLADMVSSERHKLY-LVF 892
           K +  R    +L R+  L  LC    T++HS   T Q  E  +  D+ S  +  LY +  
Sbjct: 309 KFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMED 368

Query: 893 SKEELRKLLQKLRESSLMLLDQ 914
           S++E RKL+ +L +    LL++
Sbjct: 369 SRDEHRKLITQLYQEFDHLLEE 390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,087,078
Number of Sequences: 37866
Number of extensions: 1537334
Number of successful extensions: 4443
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 4441
Number of HSP's gapped (non-prelim): 9
length of query: 925
length of database: 18,247,518
effective HSP length: 112
effective length of query: 813
effective length of database: 14,006,526
effective search space: 11387305638
effective search space used: 11387305638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.