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Search of human proteins with 9966809
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966809 kappa B-ras 1 [Homo sapiens]
(192 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966809 kappa B-ras 1 [Homo sapiens] 382 e-107
gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a [Ho... 277 3e-75
gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 277 3e-75
gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 277 3e-75
gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b [Ho... 164 4e-41
gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c [Ho... 91 5e-19
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 86 1e-17
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 84 1e-16
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 84 1e-16
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 83 1e-16
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 81 5e-16
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 81 5e-16
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 81 5e-16
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 80 8e-16
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 80 1e-15
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 80 1e-15
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 77 9e-15
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 77 1e-14
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 76 2e-14
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 75 3e-14
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 75 4e-14
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 73 1e-13
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 73 1e-13
gi|38490537 RAB7B, member RAS oncogene family [Homo sapiens] 73 1e-13
gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 73 2e-13
gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 73 2e-13
gi|169161292 PREDICTED: similar to related RAS viral (r-ras) onc... 73 2e-13
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens] 72 3e-13
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 71 5e-13
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 70 8e-13
>gi|9966809 kappa B-ras 1 [Homo sapiens]
Length = 192
Score = 382 bits (982), Expect = e-107
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
Sbjct: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
Query: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
Sbjct: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
Query: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
Sbjct: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
Query: 181 GRKNKGNSNSEN 192
GRKNKGNSNSEN
Sbjct: 181 GRKNKGNSNSEN 192
>gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 277 bits (709), Expect = 3e-75
Identities = 135/189 (71%), Positives = 160/189 (84%), Gaps = 1/189 (0%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+ Y
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
DTRGL++G ELP+H FS DG+VLVYS ++ ESFQRVELLKKEIDK KDKKEV IVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
K DL EQR+VD +VAQ WAKSEKV+LWEV+V DR++L+EPF LASK++QPQSKS+FPL
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL- 179
Query: 181 GRKNKGNSN 189
RKNKG+ +
Sbjct: 180 SRKNKGSGS 188
>gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 277 bits (709), Expect = 3e-75
Identities = 135/189 (71%), Positives = 160/189 (84%), Gaps = 1/189 (0%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+ Y
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
DTRGL++G ELP+H FS DG+VLVYS ++ ESFQRVELLKKEIDK KDKKEV IVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
K DL EQR+VD +VAQ WAKSEKV+LWEV+V DR++L+EPF LASK++QPQSKS+FPL
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL- 179
Query: 181 GRKNKGNSN 189
RKNKG+ +
Sbjct: 180 SRKNKGSGS 188
>gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 277 bits (709), Expect = 3e-75
Identities = 135/189 (71%), Positives = 160/189 (84%), Gaps = 1/189 (0%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+ Y
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
DTRGL++G ELP+H FS DG+VLVYS ++ ESFQRVELLKKEIDK KDKKEV IVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
K DL EQR+VD +VAQ WAKSEKV+LWEV+V DR++L+EPF LASK++QPQSKS+FPL
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL- 179
Query: 181 GRKNKGNSN 189
RKNKG+ +
Sbjct: 180 SRKNKGSGS 188
>gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b [Homo
sapiens]
Length = 135
Score = 164 bits (415), Expect = 4e-41
Identities = 93/189 (49%), Positives = 113/189 (59%), Gaps = 57/189 (30%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETD
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD---------- 50
Query: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
RG++E +V IVVLGN
Sbjct: 51 --RGVRE--------------------------------------------QVTIVVLGN 64
Query: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
K DL EQR+VD +VAQ WAKSEKV+LWEV+V DR++L+EPF LASK++QPQSKS+FPL
Sbjct: 65 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL- 123
Query: 181 GRKNKGNSN 189
RKNKG+ +
Sbjct: 124 SRKNKGSGS 132
>gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c
[Homo sapiens]
Length = 97
Score = 91.3 bits (225), Expect = 5e-19
Identities = 41/57 (71%), Positives = 48/57 (84%)
Query: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQL 57
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 86.3 bits (212), Expect = 1e-17
Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 6/186 (3%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF+ + +++I + KD ++V +V++GNK DL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL- 120
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKNK 185
R VD + AQ A+S + E + R+ + + F L ++ + + K S G+K K
Sbjct: 121 PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMS--KDGKKKK 178
Query: 186 GNSNSE 191
S ++
Sbjct: 179 KKSKTK 184
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 83.6 bits (205), Expect = 1e-16
Identities = 56/169 (33%), Positives = 92/169 (54%), Gaps = 4/169 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF+ + +++I + KD ++V +V++GNK DL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL- 120
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSK 174
R VD + AQ A+S + E + R+ + + F L ++ Q + K
Sbjct: 121 PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLK 169
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 83.6 bits (205), Expect = 1e-16
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 4/169 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF + L +++I + KD +V +V++GNK DL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL- 120
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSK 174
R VD + A + AKS + E + R+ + + F L ++ Q + K
Sbjct: 121 PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMK 169
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 83.2 bits (204), Expect = 1e-16
Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 3/168 (1%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVV+ G VGKT++ Q + G + G + T+E+ Y V + + LHL DT G
Sbjct: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDP--TVENTYSKIVTLGKD-EFHLHLVDTAGQ 64
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
E LP + G+VLVYSV +L SFQ +E L +++ + K V +V++GNK DLS
Sbjct: 65 DEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLS 124
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQS 173
+R+V A ++ A+S E + + + FT + ++++ ++
Sbjct: 125 PEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVEN 172
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 81.3 bits (199), Expect = 5e-16
Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 4/173 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF+ + +++I + KD +V +V++GNK DL+
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA 121
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFP 178
R V++ AQ A+S + E + R+ + + F L ++ Q + + P
Sbjct: 122 -ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNP 173
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 81.3 bits (199), Expect = 5e-16
Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 4/173 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF+ + +++I + KD +V +V++GNK DL+
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA 121
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFP 178
R V++ AQ A+S + E + R+ + + F L ++ Q + + P
Sbjct: 122 -ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNP 173
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 81.3 bits (199), Expect = 5e-16
Identities = 59/183 (32%), Positives = 91/183 (49%), Gaps = 7/183 (3%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMAS-VETDRGVKEQLHLYDTRG 64
++VV G VGK+A+ Q + + T+ED Y V DR + L + DT G
Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYDP--TIEDSYTKQCVIDDRAAR--LDILDTAG 71
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDL 124
+E + + Y +GF+LV+SV + SF+ + +++I + KD+ E ++++GNK DL
Sbjct: 72 QEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADL 131
Query: 125 SEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLS--QPQSKSSFPLPGR 182
QRQV E QQ A+ KV E + R + + F L + Q Q P P R
Sbjct: 132 DHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTR 191
Query: 183 KNK 185
K K
Sbjct: 192 KEK 194
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 80.5 bits (197), Expect = 8e-16
Identities = 54/175 (30%), Positives = 86/175 (49%), Gaps = 3/175 (1%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ Q + + T+ED Y D G+ +L + DT G
Sbjct: 31 KLVVVGGGGVGKSALTIQFIQSYFVSDYDP--TIEDSYTKICSVD-GIPARLDILDTAGQ 87
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + + Y GF+LV+++N+ +SF V L +I + KD+ + +V++GNK DL
Sbjct: 88 EEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLE 147
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
QRQV A + S V +E + R + E F L + + Q + P P
Sbjct: 148 SQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSP 202
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 80.1 bits (196), Expect = 1e-15
Identities = 53/181 (29%), Positives = 93/181 (51%), Gaps = 5/181 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCE-TMEDVYMASVETDRGVKEQLHLYDTRG 64
KV++ G VGK+A+ Q +Y +ED E T D Y V D G + Q+ + DT G
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEF---VEDYEPTKADSYRKKVVLD-GEEVQIDILDTAG 71
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDL 124
++ + +YF +GF+ V+S+ +ESF +++I + K+ + V +++GNK DL
Sbjct: 72 QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
Query: 125 SEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKN 184
++RQV E A+ A+ V E + R + + F L ++ + + S G+K
Sbjct: 132 EDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKK 191
Query: 185 K 185
+
Sbjct: 192 R 192
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 79.7 bits (195), Expect = 1e-15
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 6/187 (3%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCE-TMEDVYMASVETDRGVKEQLHLYDTRG 64
KV++ G VGK+A+ Q +Y +ED E T D Y V D G + Q+ + DT G
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEF---VEDYEPTKADSYRKKVVLD-GEEVQIDILDTAG 71
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFK-DKKEVAIVVLGNKID 123
++ + +YF +GF+LV+S+ ESF +++I + K ++ ++ ++V+GNK D
Sbjct: 72 QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSD 131
Query: 124 LSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRK 183
L E+RQV E A+ A+ V+ E + R + + F L ++ + + G+K
Sbjct: 132 LEERRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKK 191
Query: 184 NKGNSNS 190
+ N S
Sbjct: 192 SSKNKKS 198
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 77.0 bits (188), Expect = 9e-15
Identities = 51/150 (34%), Positives = 83/150 (55%), Gaps = 4/150 (2%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+VV G VGK+A+ QL+ NH + D T+ED Y V D G L + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+E + Y +GF+ V+++NN +SF+ + +++I + KD +V +V++GNK DL+
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA 121
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRK 155
R V++ AQ A+S + E + R+
Sbjct: 122 -ARTVESRQAQDLARSYGIPYIETSAKTRQ 150
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 76.6 bits (187), Expect = 1e-14
Identities = 44/137 (32%), Positives = 76/137 (55%), Gaps = 7/137 (5%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVVV G VGK+A+ Q + G + T+ED Y +E D L + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDP--TIEDFYRKEIEVDSS-PSVLEILDTAGT 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
++ + Y GF+LVYS+ N +SFQ ++ ++ +I + K ++V ++++GNK+DL
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
Query: 126 EQRQVDAE----VAQQW 138
+R+V + +A++W
Sbjct: 122 SEREVSSSEGRALAEEW 138
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 75.9 bits (185), Expect = 2e-14
Identities = 45/137 (32%), Positives = 76/137 (55%), Gaps = 7/137 (5%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVVV G VGK+A+ Q + G + T+ED Y +E D L + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDP--TIEDFYRKEIEVDSS-PSVLEILDTAGT 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
++ + Y GF+LVYS+ N +SFQ ++ ++ +I + K ++V ++++GNK+DL
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLE 121
Query: 126 EQRQVDAE----VAQQW 138
+R+V + +AQ+W
Sbjct: 122 PEREVMSSEGRALAQEW 138
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 75.1 bits (183), Expect = 3e-14
Identities = 46/164 (28%), Positives = 85/164 (51%), Gaps = 3/164 (1%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVVV G VGK+A+ Q + G+ + T+ED Y +E D L + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGSFIEKYDP--TIEDFYRKEIEVDSS-PSVLEILDTAGT 61
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
++ + Y GF+LVYS+ N +SFQ ++ ++ +I + K + V ++++GNK+DL
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLE 121
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLS 169
+R+V + A+ E + ++ ++ E F + +++
Sbjct: 122 GEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMN 165
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 74.7 bits (182), Expect = 4e-14
Identities = 51/171 (29%), Positives = 82/171 (47%), Gaps = 3/171 (1%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVV+ G VGK+A+ Q + +H T+ED Y V D L + DT G
Sbjct: 22 KVVMLGAGGVGKSAMTMQFI--SHQFPDYHDPTIEDAYKTQVRIDNE-PAYLDILDTAGQ 78
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
E + + Y +GF++ YSV + +SFQ K+ I + + E+ +V++GNKIDL
Sbjct: 79 AEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLE 138
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSS 176
+ RQV E A+ +E + R + + F L ++ + +S S
Sbjct: 139 QFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPS 189
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 73.2 bits (178), Expect = 1e-13
Identities = 55/185 (29%), Positives = 93/185 (50%), Gaps = 11/185 (5%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCE-TMEDVYMASVETDRGVKEQLHLYDTRG 64
K+VV G VGK+A+ Q + G I +E + T+ED Y VE D + L + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQG---IFVEKYDPTIEDSYRKQVEVD-AQQCMLEILDTAG 60
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDL 124
++ + Y GF LVYS+ +F ++ L+++I + KD +V ++++GNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 125 SEQRQVDAEVAQQWAKS-EKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRK 183
++R V E Q A+ E + + + E F L ++++ P+PG+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-----KTPVPGKA 175
Query: 184 NKGNS 188
K +S
Sbjct: 176 RKKSS 180
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 73.2 bits (178), Expect = 1e-13
Identities = 55/185 (29%), Positives = 93/185 (50%), Gaps = 11/185 (5%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCE-TMEDVYMASVETDRGVKEQLHLYDTRG 64
K+VV G VGK+A+ Q + G I +E + T+ED Y VE D + L + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQG---IFVEKYDPTIEDSYRKQVEVD-AQQCMLEILDTAG 60
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDL 124
++ + Y GF LVYS+ +F ++ L+++I + KD +V ++++GNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 125 SEQRQVDAEVAQQWAKS-EKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRK 183
++R V E Q A+ E + + + E F L ++++ P+PG+
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-----KTPVPGKA 175
Query: 184 NKGNS 188
K +S
Sbjct: 176 RKKSS 180
>gi|38490537 RAB7B, member RAS oncogene family [Homo sapiens]
Length = 199
Score = 73.2 bits (178), Expect = 1e-13
Identities = 48/171 (28%), Positives = 96/171 (56%), Gaps = 6/171 (3%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+++ G + VGKT++ Q Y + T E T+ ++ + +L ++DT G
Sbjct: 10 KLIIVGAIGVGKTSLPHQ--YVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTGGQ 67
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEI--DKFKDKKEVAIVVLGNKID 123
+ + ++ +DG +L + V +LESF+ +++ + ++ ++ +V+LGNKID
Sbjct: 68 ERFRSMVSTFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPMEQSYPMVLLGNKID 127
Query: 124 LSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASK-LSQPQS 173
L++ R+V EVAQ W + + + +EV+ + +++ F +LAS+ LS+ QS
Sbjct: 128 LAD-RKVPQEVAQGWCREKDIPYFEVSAKNDINVVQAFEMLASRALSRYQS 177
>gi|169160721 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 5/151 (3%)
Query: 38 TMEDVYMAS-VETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQR 96
T ED Y V DR + L + DT G +E + + Y +GF+LV+SV + SF+
Sbjct: 27 TNEDSYTKQCVIDDRAAR--LDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDRGSFEE 84
Query: 97 VELLKKEIDKFKDKKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKT 156
+ +++I + KD+ E ++++GNK DL QRQV E +Q A+ KV E + R
Sbjct: 85 IYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASAKIRMN 144
Query: 157 LIEPFTLLASKLS--QPQSKSSFPLPGRKNK 185
+ + F L + Q Q P P RK K
Sbjct: 145 VDQAFHELVRVIRKFQEQECPPSPEPTRKEK 175
>gi|169161589 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 5/151 (3%)
Query: 38 TMEDVYMAS-VETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQR 96
T ED Y V DR + L + DT G +E + + Y +GF+LV+SV + SF+
Sbjct: 27 TNEDSYTKQCVIDDRAAR--LDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDRGSFEE 84
Query: 97 VELLKKEIDKFKDKKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKT 156
+ +++I + KD+ E ++++GNK DL QRQV E +Q A+ KV E + R
Sbjct: 85 IYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASAKIRMN 144
Query: 157 LIEPFTLLASKLS--QPQSKSSFPLPGRKNK 185
+ + F L + Q Q P P RK K
Sbjct: 145 VDQAFHELVRVIRKFQEQECPPSPEPTRKEK 175
>gi|169161292 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 5/151 (3%)
Query: 38 TMEDVYMAS-VETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQR 96
T ED Y V DR + L + DT G +E + + Y +GF+LV+SV + SF+
Sbjct: 27 TNEDSYTKQCVIDDRAAR--LDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDRGSFEE 84
Query: 97 VELLKKEIDKFKDKKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKT 156
+ +++I + KD+ E ++++GNK DL QRQV E +Q A+ KV E + R
Sbjct: 85 IYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASAKIRMN 144
Query: 157 LIEPFTLLASKLS--QPQSKSSFPLPGRKNK 185
+ + F L + Q Q P P RK K
Sbjct: 145 VDQAFHELVRVIRKFQEQECPPSPEPTRKEK 175
>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 72.0 bits (175), Expect = 3e-13
Identities = 49/182 (26%), Positives = 96/182 (52%), Gaps = 9/182 (4%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
K+V+ G VGKT ++ + G G + D + +VE + G K +L ++DT G
Sbjct: 11 KIVLIGNAGVGKTCLVRRFTQGLFPPG-QGATIGVDFMIKTVEIN-GEKVKLQIWDTAGQ 68
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+ + + Y+ A+ +L Y + ESF+ + +EI+++ K + ++V GNKIDL+
Sbjct: 69 ERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLV-GNKIDLA 127
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKS------SFPL 179
E+R+V + A+++++++ + E + + + + F LA +L ++ S PL
Sbjct: 128 ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPL 187
Query: 180 PG 181
PG
Sbjct: 188 PG 189
>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
Length = 225
Score = 71.2 bits (173), Expect = 5e-13
Identities = 49/186 (26%), Positives = 93/186 (50%), Gaps = 9/186 (4%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGL 65
KVV+ G VGKT+++ L Y + + T++ ++ G + L ++DT G
Sbjct: 21 KVVLLGEGCVGKTSLV--LRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 78
Query: 66 QEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLS 125
+ L Y+ ++G +LVY + + +SFQ+V+ KE+ K E+ + ++GNKIDL
Sbjct: 79 ERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGN-EICLCIVGNKIDLE 137
Query: 126 EQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKNK 185
++R V + A+ +A+S + + + K + E F L ++ + + K
Sbjct: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVD------ERAK 191
Query: 186 GNSNSE 191
GN +S+
Sbjct: 192 GNGSSQ 197
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 70.5 bits (171), Expect = 8e-13
Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 9/138 (6%)
Query: 6 KVVVCGLLSVGKTAILEQLLYGNHTIGMEDCE-TMEDVYMASVETDRGVKEQLHLYDTRG 64
K+VV G VGK+A+ Q + G I +E + T+ED Y VE D + L + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQG---IFVEKYDPTIEDSYRKQVEVDCQ-QCMLEILDTAG 60
Query: 65 LQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDL 124
++ + Y GF LVYS+ +F ++ L+++I + KD ++V ++++GNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 125 SEQRQVDAE----VAQQW 138
++R V E +A+QW
Sbjct: 121 EDERVVGKEQGQNLARQW 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,623,082
Number of Sequences: 37866
Number of extensions: 252735
Number of successful extensions: 914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 687
Number of HSP's gapped (non-prelim): 209
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.