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Search of human proteins with 9790235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 1062 0.0
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 678 0.0
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 461 e-130
gi|115648063 solute carrier family 7 (cationic amino acid transp... 454 e-128
gi|115648022 solute carrier family 7 (cationic amino acid transp... 454 e-128
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 430 e-120
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 430 e-120
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 430 e-120
gi|33286430 solute carrier family 7 (cationic amino acid transpo... 418 e-117
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 403 e-112
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 369 e-102
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 369 e-102
gi|71999149 solute carrier family 7, (cationic amino acid transp... 233 4e-61
gi|110347453 solute carrier family 7 (cationic amino acid transp... 95 2e-19
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 84 2e-16
gi|114326550 solute carrier family 7 (cationic amino acid transp... 80 5e-15
gi|114326544 solute carrier family 7 (cationic amino acid transp... 80 5e-15
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 80 6e-15
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 79 1e-14
gi|181337167 solute carrier family 7 (cationic amino acid transp... 69 1e-11
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 41 0.002
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 37 0.034
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 37 0.034
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 37 0.034
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 37 0.034
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 37 0.034
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 37 0.034
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 37 0.057
gi|123701900 solute carrier family 12 (potassium/chloride transp... 35 0.17
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 34 0.37
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 1062 bits (2747), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFI 60
MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFI
Sbjct: 1 MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFI 60
Query: 61 SPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGF 120
SPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGF
Sbjct: 61 SPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGF 120
Query: 121 LLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSV 180
LLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSV
Sbjct: 121 LLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSV 180
Query: 181 RWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQ 240
RWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQ
Sbjct: 181 RWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQ 240
Query: 241 GSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSN 300
GSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSN
Sbjct: 241 GSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSN 300
Query: 301 AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR 360
AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR
Sbjct: 301 AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR 360
Query: 361 HCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPI 420
HCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPI
Sbjct: 361 HCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPI 420
Query: 421 KVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLT 480
KVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLT
Sbjct: 421 KVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLT 480
Query: 481 ESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ 523
ESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ
Sbjct: 481 ESMTHWGQELCFVVYPQDAPEEEENGPCPPSLLPATDKPSKPQ 523
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 678 bits (1750), Expect = 0.0
Identities = 325/477 (68%), Positives = 396/477 (83%), Gaps = 3/477 (0%)
Query: 21 SPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWV 80
SP G+ G VALKKEIGL+SAC II+GNIIGSGIF+SPKGVLE++GSVGLAL VW+
Sbjct: 24 SPEAGSGGGG---VALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWI 80
Query: 81 LGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISM 140
+ G +T +G+LCYAELGV IPKSGGDY+YV +IFGGLAGFL LW AVL++YPT+ AVI++
Sbjct: 81 VTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIAL 140
Query: 141 TFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSL 200
TFSNYVLQP+FP C PP + R+L+ CL+LLTWVN SSVRWATR+QD+FT GKLLAL+L
Sbjct: 141 TFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALAL 200
Query: 201 IIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVD 260
II +G++QI +G + L P NAF + P +G +ALAFLQGSFA+ GWNFLNYVTEE+VD
Sbjct: 201 IIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVD 260
Query: 261 ARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPV 320
KNLPRAIFISIPLVTFVY F N+AY TAMSPQELL+SNAVAVTFGEKLLG +W+MP+
Sbjct: 261 PYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPI 320
Query: 321 SVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIML 380
SVALSTFGG+NG LFT SRL F+GAREGHLPS+LAMIHV+ CTPIPALL C +T ++++
Sbjct: 321 SVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLV 380
Query: 381 VGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVF 440
D YTLINYV FINYL YGVT+ G ++LRW++P + RPIK+NLL P+ YL+FWAFLLVF
Sbjct: 381 TSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVF 440
Query: 441 SFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQ 497
S SEP+VCG+G+ I+LTGVP++FLGV+W+ KPKC E +T Q++C VVYP+
Sbjct: 441 SLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 497
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 461 bits (1187), Expect = e-130
Identities = 235/476 (49%), Positives = 330/476 (69%), Gaps = 5/476 (1%)
Query: 25 GTVP-GASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGG 83
G+ P G E V L++ I LL+ II+G IIGSGIF++P GVL+ +GS GLAL VW G
Sbjct: 34 GSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACG 93
Query: 84 GVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFS 143
+ +G+LCYAELG I KSGGDYAY+ E++G L FL LW +LI+ P+S ++++ F+
Sbjct: 94 VFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFA 153
Query: 144 NYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203
Y+L+P+FP C P A+++++ C++LLT VN SV+ ATR+QD F KLLAL+LII
Sbjct: 154 TYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIIL 213
Query: 204 VGLLQIFQGHFEELRPSNAFAFWMTP-SVGHLALAFLQGSFAFSGWNFLNYVTEEMVDAR 262
+G +QI +G L P+ F+F T VG++ LA G FA+ GWN+LN+VTEEM++
Sbjct: 214 LGFVQIGKGDVSNLDPN--FSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPY 271
Query: 263 KNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSV 322
+NLP AI IS+P+VT VY TN+AYFT +S +++LSS AVAV FG LG SW++PV V
Sbjct: 272 RNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFV 331
Query: 323 ALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVG 382
LS FG +NG LFT SRL F G+REGHLPS+L+MIH + TP+P+L+ C T +
Sbjct: 332 GLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSK 391
Query: 383 DTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSF 442
D +++IN+ SF N+LC + I+G++ LR R+P L RPIKVNL +PV +++ FL+ SF
Sbjct: 392 DIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSF 451
Query: 443 ISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 498
P+ CG+G IIL+G+P++F GV+W++KPK + + S T Q+L VV PQ+
Sbjct: 452 WKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVV-PQE 506
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 454 bits (1168), Expect = e-128
Identities = 222/506 (43%), Positives = 336/506 (66%), Gaps = 18/506 (3%)
Query: 15 RPAPSPSPVPGTVPG------------ASERVALKKEIGLLSACTIIIGNIIGSGIFISP 62
RP P+ VP T +SE + LKKEI LL+ ++++GN+IGSGIF+SP
Sbjct: 8 RPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSP 67
Query: 63 KGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLL 122
KGVL H+ S G++L VW +GG + +G+LCYAELG I KSG YAY+ E FGG F+
Sbjct: 68 KGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIR 127
Query: 123 LWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRW 182
LW ++L++ PT A+I++TF+NY++QP FP+C PP A R+L+ AC+ LLT+VN + V+W
Sbjct: 128 LWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKW 187
Query: 183 ATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGS 242
TR+QD FT K++AL II +GL+++ QGH E + + + W +G+L+LA
Sbjct: 188 GTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSW---DMGNLSLALYSAL 244
Query: 243 FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAV 302
F++SGW+ LN+VTEE+ + +NLP AI IS+P+VT +Y TN+AY+T ++ ++LSS+AV
Sbjct: 245 FSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAV 304
Query: 303 AVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHC 362
AVTF ++ G FSW +P++VALS FGG+N +F SRL F G+REGHLP LL+MIH+
Sbjct: 305 AVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERF 364
Query: 363 TPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKV 422
TPIPALL C + ++V D + LINY SF + G++++G L LRW+ P RP+K+
Sbjct: 365 TPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKL 424
Query: 423 NLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFW--RSKPKCVHRLT 480
++ P+ + + FL++ ++ + +G+ I L+GVP +F+GV+ +P + +
Sbjct: 425 SVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVL 484
Query: 481 ESMTHWGQELCFVVYPQ-DAPEEEEN 505
++T Q+LCF V + D EE+++
Sbjct: 485 AAITRGTQQLCFCVLTELDVAEEKKD 510
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 454 bits (1168), Expect = e-128
Identities = 222/506 (43%), Positives = 336/506 (66%), Gaps = 18/506 (3%)
Query: 15 RPAPSPSPVPGTVPG------------ASERVALKKEIGLLSACTIIIGNIIGSGIFISP 62
RP P+ VP T +SE + LKKEI LL+ ++++GN+IGSGIF+SP
Sbjct: 8 RPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSP 67
Query: 63 KGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLL 122
KGVL H+ S G++L VW +GG + +G+LCYAELG I KSG YAY+ E FGG F+
Sbjct: 68 KGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIR 127
Query: 123 LWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRW 182
LW ++L++ PT A+I++TF+NY++QP FP+C PP A R+L+ AC+ LLT+VN + V+W
Sbjct: 128 LWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKW 187
Query: 183 ATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGS 242
TR+QD FT K++AL II +GL+++ QGH E + + + W +G+L+LA
Sbjct: 188 GTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSW---DMGNLSLALYSAL 244
Query: 243 FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAV 302
F++SGW+ LN+VTEE+ + +NLP AI IS+P+VT +Y TN+AY+T ++ ++LSS+AV
Sbjct: 245 FSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAV 304
Query: 303 AVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHC 362
AVTF ++ G FSW +P++VALS FGG+N +F SRL F G+REGHLP LL+MIH+
Sbjct: 305 AVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERF 364
Query: 363 TPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKV 422
TPIPALL C + ++V D + LINY SF + G++++G L LRW+ P RP+K+
Sbjct: 365 TPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKL 424
Query: 423 NLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFW--RSKPKCVHRLT 480
++ P+ + + FL++ ++ + +G+ I L+GVP +F+GV+ +P + +
Sbjct: 425 SVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVL 484
Query: 481 ESMTHWGQELCFVVYPQ-DAPEEEEN 505
++T Q+LCF V + D EE+++
Sbjct: 485 AAITRGTQQLCFCVLTELDVAEEKKD 510
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 430 bits (1106), Expect = e-120
Identities = 219/508 (43%), Positives = 328/508 (64%), Gaps = 13/508 (2%)
Query: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74
+P SP+ E+V LKKEI LL+ +I+GN+IGSGIF+SPKGVL +S S GL
Sbjct: 12 QPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGL 71
Query: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTS 134
+L +W +GG + G+LCYAELG I KSG YAY+ E FGG F+ LW+++LI+ PTS
Sbjct: 72 SLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 131
Query: 135 LAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGK 194
A+I++TF+NY++QP+FP+C P ASR+L+ AC+ LLT++N + V+W T +QD+FT K
Sbjct: 132 QAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
Query: 195 LLALSLIIGVGLLQIFQG---HFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251
+LAL +I G++++ QG HFE ++FA VG +ALA F++SGW+ L
Sbjct: 192 VLALIAVIVAGIVRLGQGASTHFENSFEGSSFA------VGDIALALYSALFSYSGWDTL 245
Query: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLL 311
NYVTEE+ + +NLP +I IS+P+VT +Y TN+AY+T + +++L+S+AVAVTF +++
Sbjct: 246 NYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIF 305
Query: 312 GYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVC 371
G F+W++P+SVALS FGG+N + SRL F G+REGHLP + MIHV TP+P+LL
Sbjct: 306 GIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYL 431
+ + V D + LINY SF + G++I+G L LRW+ P RP+K+++ P+ +
Sbjct: 366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFC 425
Query: 432 VFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFL--GVFWRSKPKCVHRLTESMTHWGQE 489
+ FL+ S+ + +G+ I L+G+P +FL V +P + R+ S T + Q
Sbjct: 426 LCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQV 485
Query: 490 LCFVVYPQDAPEEEENGPCPPSLLPATD 517
LC V + + E+ G P P ++
Sbjct: 486 LCMSVAAE--MDLEDGGEMPKQRDPKSN 511
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 430 bits (1106), Expect = e-120
Identities = 219/508 (43%), Positives = 328/508 (64%), Gaps = 13/508 (2%)
Query: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74
+P SP+ E+V LKKEI LL+ +I+GN+IGSGIF+SPKGVL +S S GL
Sbjct: 12 QPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGL 71
Query: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTS 134
+L +W +GG + G+LCYAELG I KSG YAY+ E FGG F+ LW+++LI+ PTS
Sbjct: 72 SLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 131
Query: 135 LAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGK 194
A+I++TF+NY++QP+FP+C P ASR+L+ AC+ LLT++N + V+W T +QD+FT K
Sbjct: 132 QAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
Query: 195 LLALSLIIGVGLLQIFQG---HFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251
+LAL +I G++++ QG HFE ++FA VG +ALA F++SGW+ L
Sbjct: 192 VLALIAVIVAGIVRLGQGASTHFENSFEGSSFA------VGDIALALYSALFSYSGWDTL 245
Query: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLL 311
NYVTEE+ + +NLP +I IS+P+VT +Y TN+AY+T + +++L+S+AVAVTF +++
Sbjct: 246 NYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIF 305
Query: 312 GYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVC 371
G F+W++P+SVALS FGG+N + SRL F G+REGHLP + MIHV TP+P+LL
Sbjct: 306 GIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYL 431
+ + V D + LINY SF + G++I+G L LRW+ P RP+K+++ P+ +
Sbjct: 366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFC 425
Query: 432 VFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFL--GVFWRSKPKCVHRLTESMTHWGQE 489
+ FL+ S+ + +G+ I L+G+P +FL V +P + R+ S T + Q
Sbjct: 426 LCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQV 485
Query: 490 LCFVVYPQDAPEEEENGPCPPSLLPATD 517
LC V + + E+ G P P ++
Sbjct: 486 LCMSVAAE--MDLEDGGEMPKQRDPKSN 511
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 430 bits (1106), Expect = e-120
Identities = 219/508 (43%), Positives = 328/508 (64%), Gaps = 13/508 (2%)
Query: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74
+P SP+ E+V LKKEI LL+ +I+GN+IGSGIF+SPKGVL +S S GL
Sbjct: 12 QPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGL 71
Query: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTS 134
+L +W +GG + G+LCYAELG I KSG YAY+ E FGG F+ LW+++LI+ PTS
Sbjct: 72 SLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 131
Query: 135 LAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGK 194
A+I++TF+NY++QP+FP+C P ASR+L+ AC+ LLT++N + V+W T +QD+FT K
Sbjct: 132 QAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAK 191
Query: 195 LLALSLIIGVGLLQIFQG---HFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251
+LAL +I G++++ QG HFE ++FA VG +ALA F++SGW+ L
Sbjct: 192 VLALIAVIVAGIVRLGQGASTHFENSFEGSSFA------VGDIALALYSALFSYSGWDTL 245
Query: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLL 311
NYVTEE+ + +NLP +I IS+P+VT +Y TN+AY+T + +++L+S+AVAVTF +++
Sbjct: 246 NYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIF 305
Query: 312 GYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVC 371
G F+W++P+SVALS FGG+N + SRL F G+REGHLP + MIHV TP+P+LL
Sbjct: 306 GIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFN 365
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYL 431
+ + V D + LINY SF + G++I+G L LRW+ P RP+K+++ P+ +
Sbjct: 366 GIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFC 425
Query: 432 VFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFL--GVFWRSKPKCVHRLTESMTHWGQE 489
+ FL+ S+ + +G+ I L+G+P +FL V +P + R+ S T + Q
Sbjct: 426 LCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQV 485
Query: 490 LCFVVYPQDAPEEEENGPCPPSLLPATD 517
LC V + + E+ G P P ++
Sbjct: 486 LCMSVAAE--MDLEDGGEMPKQRDPKSN 511
>gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo
sapiens]
Length = 332
Score = 418 bits (1075), Expect = e-117
Identities = 196/294 (66%), Positives = 241/294 (81%)
Query: 204 VGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARK 263
+G++QI +G + L P NAF + P +G +ALAFLQGSFA+ GWNFLNYVTEE+VD K
Sbjct: 1 MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYK 60
Query: 264 NLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVA 323
NLPRAIFISIPLVTFVY F N+AY TAMSPQELL+SNAVAVTFGEKLLG +W+MP+SVA
Sbjct: 61 NLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA 120
Query: 324 LSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGD 383
LSTFGG+NG LFT SRL F+GAREGHLPS+LAMIHV+ CTPIPALL C +T ++++ D
Sbjct: 121 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSD 180
Query: 384 TYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFI 443
YTLINYV FINYL YGVT+ G ++LRW++P + RPIK+NLL P+ YL+FWAFLLVFS
Sbjct: 181 MYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLW 240
Query: 444 SEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQ 497
SEP+VCG+G+ I+LTGVP++FLGV+W+ KPKC E +T Q++C VVYP+
Sbjct: 241 SEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPE 294
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 403 bits (1036), Expect = e-112
Identities = 206/471 (43%), Positives = 307/471 (65%), Gaps = 3/471 (0%)
Query: 28 PGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTA 87
P E+V LK+++ LL +IIIG IIG+GIFISPKGVL+++GSVG++L +W + G ++
Sbjct: 32 PPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSL 91
Query: 88 LGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVL 147
G+L YAELG I KSGG Y Y+ E+FG L F+ +W +LI+ P + AVIS+ F Y+L
Sbjct: 92 FGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYIL 151
Query: 148 QPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLL 207
+P F C P A ++++ + ++ +NS SV W+ RIQ T KL A+ +II G++
Sbjct: 152 EPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVM 211
Query: 208 QIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPR 267
Q+ +G + + +AF+ S+ L LAF G +A++GW +LN+VTEE+ + K +P
Sbjct: 212 QLIKGQTQNFK--DAFS-GRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPL 268
Query: 268 AIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTF 327
AI IS+ +VT Y TN+AYFT ++ +ELL SNAVAVTF E+LLG FS +P+ VALS F
Sbjct: 269 AICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCF 328
Query: 328 GGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTL 387
G +NG +F SRL + +REGHLP +L+MIHVR TP+PA++V T +++ GD +L
Sbjct: 329 GSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSL 388
Query: 388 INYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPM 447
+N++SF +L G+ + GL+ LR++ P +HRP KV L IP + F++ S S+P
Sbjct: 389 LNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPF 448
Query: 448 VCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 498
G+G +I LTGVP ++L + W KP+ ++E +T Q + VV +D
Sbjct: 449 STGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 369 bits (946), Expect = e-102
Identities = 199/471 (42%), Positives = 300/471 (63%), Gaps = 12/471 (2%)
Query: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94
+L+KE+GL+S +II+G IIGSGIF+SPK VL ++ +VG L +W G + LG+LC+A
Sbjct: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
Query: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
ELG I KSGG+Y Y+ E +G + +L W++++++ PTS A+I ++FS YV P + C
Sbjct: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
Query: 155 IPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHF 214
PP + L+ A ++ ++ VNS SVR + +Q++FT KL+ +++II GL+ + QG+
Sbjct: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
Query: 215 EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIP 274
+ N+F SVG ++LAF G +A+ GWN LNY+TEE+ + +NLP AI I IP
Sbjct: 205 KNF--DNSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
Query: 275 LVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYL 334
LVT Y N++YFT M+ ELL S AVAVTFG+++L SW++P+ VA ST G NG
Sbjct: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
Query: 335 FTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI 394
FT RL + REGH+ +L+ I VR TP PA++ + ++ GD +L+NY SF
Sbjct: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
Query: 395 NYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP----MVCG 450
+L YG+TILGL+++R+ R L RPIKV ++IPV + FL++ IS+P + C
Sbjct: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
Query: 451 VGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPE 501
V+ IL+G+ +FL V + K ++++ +T Q L VV P++ PE
Sbjct: 441 --VLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 369 bits (946), Expect = e-102
Identities = 199/471 (42%), Positives = 300/471 (63%), Gaps = 12/471 (2%)
Query: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94
+L+KE+GL+S +II+G IIGSGIF+SPK VL ++ +VG L +W G + LG+LC+A
Sbjct: 25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFA 84
Query: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
ELG I KSGG+Y Y+ E +G + +L W++++++ PTS A+I ++FS YV P + C
Sbjct: 85 ELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGC 144
Query: 155 IPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHF 214
PP + L+ A ++ ++ VNS SVR + +Q++FT KL+ +++II GL+ + QG+
Sbjct: 145 KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNT 204
Query: 215 EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIP 274
+ N+F SVG ++LAF G +A+ GWN LNY+TEE+ + +NLP AI I IP
Sbjct: 205 KNF--DNSFEGAQL-SVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIP 261
Query: 275 LVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYL 334
LVT Y N++YFT M+ ELL S AVAVTFG+++L SW++P+ VA ST G NG
Sbjct: 262 LVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTC 321
Query: 335 FTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI 394
FT RL + REGH+ +L+ I VR TP PA++ + ++ GD +L+NY SF
Sbjct: 322 FTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFA 381
Query: 395 NYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEP----MVCG 450
+L YG+TILGL+++R+ R L RPIKV ++IPV + FL++ IS+P + C
Sbjct: 382 AWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYC- 440
Query: 451 VGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPE 501
V+ IL+G+ +FL V + K ++++ +T Q L VV P++ PE
Sbjct: 441 --VLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEEDPE 487
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 233 bits (593), Expect = 4e-61
Identities = 144/457 (31%), Positives = 246/457 (53%), Gaps = 12/457 (2%)
Query: 32 ERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSG-SVGLALFVWVLGGGVTALGS 90
E++ LK+ G + ++ NIIG+GIF+SPKGVL +S +VG++L VW + +
Sbjct: 5 EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64
Query: 91 LCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPV 150
LC AE+ ++ P SG Y ++ FG FL LW++ L + +A ++ + Y +QP
Sbjct: 65 LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTS-LFLGSGVVAGQALLLAEYSIQPF 123
Query: 151 FPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIF 210
FP+C P + L++A L ++ + S V+ T +Q + K+ LS I G++ +
Sbjct: 124 FPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLI 183
Query: 211 QGHFEEL-RPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAI 269
+G E + R NAF + P + HL A QG FA+SG + E+ R +P+ I
Sbjct: 184 RGKKENVERFQNAFDAEL-PDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCI 242
Query: 270 FISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGG 329
F ++PLVT VY NI+Y T ++P+E+LSS+AVA+T+ ++ +W+MP +++ S F
Sbjct: 243 FTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSN 302
Query: 330 INGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLIN 389
+ +F SR + ++EG LP L ++ H +P A+L+ ++ +++ LIN
Sbjct: 303 LLISIFKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLIN 361
Query: 390 YVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVC 449
Y+ F L + ++G+L R++ P L P KV L P+A +V L+V + P V
Sbjct: 362 YIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVH 421
Query: 450 GVGVIIILTGVPIFFLGVF-------WRSKPKCVHRL 479
V V++++ +F++ + W K C +L
Sbjct: 422 YVYVLLLVLSGLLFYIPLIHFKIRLAWFEKMTCYLQL 458
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 94.7 bits (234), Expect = 2e-19
Identities = 85/393 (21%), Positives = 171/393 (43%), Gaps = 22/393 (5%)
Query: 35 ALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYA 94
+L++ + L + +G ++GSG+++ V + + L V + L +LCYA
Sbjct: 32 SLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGV-AAVASLLAALCYA 90
Query: 95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
E G +P++G Y + G L FL+ W+ VL+ Y A ++ +S Y L +F +
Sbjct: 91 EFGARVPRTGSAYLFTYVSMGELWAFLIGWN-VLLEYIIGGAAVARAWSGY-LDSMFSHS 148
Query: 155 IPPTTASRV--------------LSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSL 200
I T + V L+ ++L + S R ++ + F+ LL +
Sbjct: 149 IRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILF 208
Query: 201 IIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVD 260
I+ +G + + Q H F + + A F +AF G++ + +EE +
Sbjct: 209 IVILGFI-LAQPHNWSADEGGFAPFGFSGVMAGTASCF----YAFVGFDVIAASSEEAQN 263
Query: 261 ARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPV 320
R+++P AI IS+ + Y + + L +A+A F ++ + +++
Sbjct: 264 PRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAA 323
Query: 321 SVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIML 380
+ + LF+ R+ ++ A +G + A +H R P+ L TA + L
Sbjct: 324 GSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLAL 383
Query: 381 VGDTYTLINYVSFINYLCYGVTILGLLLLRWRR 413
+ D +L+ ++S L Y +++LR+++
Sbjct: 384 LLDLESLVQFLSLGTLLAYTFVATSIIVLRFQK 416
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/417 (22%), Positives = 179/417 (42%), Gaps = 43/417 (10%)
Query: 32 ERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSL 91
E L + + + +G+ +G+G+++ V + + + +++ + L L
Sbjct: 24 EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVIS-FLIAALASVLAGL 82
Query: 92 CYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVL--IMYPTSLA-VISMTFSNYVLQ 148
CY E G +PK+G Y Y G L F+ W+ +L I+ +S+A S TF + +
Sbjct: 83 CYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGR 142
Query: 149 PV--FPNCIPPTTASRVL-------SMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALS 199
P+ F A VL ++ +++LT + + V+ + + +FT +L L
Sbjct: 143 PIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLG 202
Query: 200 LIIGVGLL-------QIFQGHF-------------EELRP--SNAFAFWMTPSVGHLALA 237
I+ G + Q+ + F +E +P F + + A
Sbjct: 203 FIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATC 262
Query: 238 FLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELL 297
F +AF G++ + EE+ + +K +P I S+ L+ F+ F A T M P L
Sbjct: 263 F----YAFVGFDCIATTGEEVKNPQKAIPVGIVASL-LICFIAYFGVSAALTLMMPYFCL 317
Query: 298 SSNAVAVTFGEKLLGY--FSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLA 355
+N+ + K +G+ + + V + + G +F R+ ++ A +G L LA
Sbjct: 318 DNNS-PLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLA 376
Query: 356 MIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR 412
++ R TPI A L AV+ + D L++ +S L Y + +L+LR++
Sbjct: 377 NVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQ 433
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 80.1 bits (196), Expect = 5e-15
Identities = 94/420 (22%), Positives = 178/420 (42%), Gaps = 39/420 (9%)
Query: 26 TVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGV 85
T+ L + + L + +G+ +G+G+++ V + + + +++
Sbjct: 18 TLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVI-CFLVAALS 76
Query: 86 TALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVL--IMYPTSLA-VISMTF 142
+ L LCYAE G +P+SG Y Y G L F W+ +L ++ S+A S F
Sbjct: 77 SVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAF 136
Query: 143 SNYV-------LQPVFPNCIPPTTAS--RVLSMACLMLLTWVNSSSVRWATRIQDMFTGG 193
N + LQ +P A ++ ++LLT + + + + +FTG
Sbjct: 137 DNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGV 196
Query: 194 KLLALSLIIGVGLL-------QIFQGHFE--ELRPSNAFAFWMTPSVGHLALAF---LQG 241
LL L ++ G + ++ + +E ++ ++ S G + F L+G
Sbjct: 197 NLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRG 256
Query: 242 S----FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELL 297
+ +AF G++ + EE + ++++P I IS+ V F+ F + T M P L
Sbjct: 257 AATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLS-VCFLAYFAVSSALTLMMPYYQL 315
Query: 298 SSNAVAVTFGEKLLGYFSW-----VMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPS 352
+ E L Y W V+ V + + G +F R+ ++ A +G L
Sbjct: 316 QPES---PLPEAFL-YIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFR 371
Query: 353 LLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR 412
+LA IH TPI A +V A + + L++ +S L Y + + +L+LR++
Sbjct: 372 VLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 80.1 bits (196), Expect = 5e-15
Identities = 94/420 (22%), Positives = 178/420 (42%), Gaps = 39/420 (9%)
Query: 26 TVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGV 85
T+ L + + L + +G+ +G+G+++ V + + + +++
Sbjct: 18 TLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVI-CFLVAALS 76
Query: 86 TALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVL--IMYPTSLA-VISMTF 142
+ L LCYAE G +P+SG Y Y G L F W+ +L ++ S+A S F
Sbjct: 77 SVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAF 136
Query: 143 SNYV-------LQPVFPNCIPPTTAS--RVLSMACLMLLTWVNSSSVRWATRIQDMFTGG 193
N + LQ +P A ++ ++LLT + + + + +FTG
Sbjct: 137 DNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGV 196
Query: 194 KLLALSLIIGVGLL-------QIFQGHFE--ELRPSNAFAFWMTPSVGHLALAF---LQG 241
LL L ++ G + ++ + +E ++ ++ S G + F L+G
Sbjct: 197 NLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRG 256
Query: 242 S----FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELL 297
+ +AF G++ + EE + ++++P I IS+ V F+ F + T M P L
Sbjct: 257 AATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLS-VCFLAYFAVSSALTLMMPYYQL 315
Query: 298 SSNAVAVTFGEKLLGYFSW-----VMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPS 352
+ E L Y W V+ V + + G +F R+ ++ A +G L
Sbjct: 316 QPES---PLPEAFL-YIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFR 371
Query: 353 LLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR 412
+LA IH TPI A +V A + + L++ +S L Y + + +L+LR++
Sbjct: 372 VLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 79.7 bits (195), Expect = 6e-15
Identities = 86/397 (21%), Positives = 169/397 (42%), Gaps = 39/397 (9%)
Query: 50 IGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAY 109
+G+ +G+G+++ V + + + +++ + + LCYAE G +PK+G Y Y
Sbjct: 44 VGSTLGAGVYVLAGEVAKADSGPSIVVS-FLIAALASVMAGLCYAEFGARVPKTGSAYLY 102
Query: 110 VTEIFGGLAGFLLLWSAVL--IMYPTSLA---------VISMTFSNYVLQPVFPNCIPPT 158
G L F+ W+ +L ++ +S+A ++S ++ N
Sbjct: 103 TYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLRTYFRMNYTGLA 162
Query: 159 TASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELR 218
++ ++LL + S V+ + + +FT +L L ++ G + +G+ +
Sbjct: 163 EYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFV---KGNVANWK 219
Query: 219 PSNAFAFWMTPSV---------------GHLALAF---LQGS----FAFSGWNFLNYVTE 256
S F ++ S G + F L G+ +AF G++ + E
Sbjct: 220 ISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGE 279
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNA-VAVTFGEKLLGYFS 315
E+ + +K +P I S+ LV F+ F A T M P LL + + V F G
Sbjct: 280 EVRNPQKAIPIGIVTSL-LVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAK 338
Query: 316 WVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGAT 375
+V+ + + G +F R+ ++ A +G L LA I+ + TPI A L
Sbjct: 339 YVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSKTKTPIIATLSSGAVA 398
Query: 376 AVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR 412
A++ + D L++ +S + Y + +L+LR++
Sbjct: 399 ALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 435
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 79.0 bits (193), Expect = 1e-14
Identities = 86/397 (21%), Positives = 170/397 (42%), Gaps = 40/397 (10%)
Query: 50 IGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAY 109
+G+ +G+G+++ V + + + +++ + + LCYAE G +PK+G Y Y
Sbjct: 84 VGSTLGAGVYVLAGEVAKADSGPSIVVS-FLIAALASVMAGLCYAEFGARVPKTGSAYLY 142
Query: 110 VTEIFGGLAGFLLLWSAVL--IMYPTSLA---------VISMTFSNYVLQPVFPNCIPPT 158
G L F+ W+ +L ++ +S+A ++S ++ N
Sbjct: 143 TYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLRTYFRMNYTGLA 202
Query: 159 TASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELR 218
++ ++LL + S V+ + + +FT +L L ++ G + +G+ +
Sbjct: 203 EYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFV---KGNVANWK 259
Query: 219 PSNAFAFWMTPSV---------------GHLALAF---LQGS----FAFSGWNFLNYVTE 256
S F ++ S G + F L G+ +AF G++ + E
Sbjct: 260 ISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGE 319
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNA-VAVTFGEKLLGYFS 315
E+ + +K +P I S+ LV F+ F A T M P LL + + V F G
Sbjct: 320 EVRNPQKAIPIGIVTSL-LVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAK 378
Query: 316 WVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGAT 375
+V+ + + G +F R+ F+ AR+G L LA + R +P+ A L +
Sbjct: 379 YVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQ-SPVAATLTAGVIS 437
Query: 376 AVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR 412
A++ + D L++ +S + Y + +L+LR++
Sbjct: 438 ALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ 474
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 68.9 bits (167), Expect = 1e-11
Identities = 87/423 (20%), Positives = 176/423 (41%), Gaps = 43/423 (10%)
Query: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74
R P S + GT + L + + + ++ +G+ +G+G+++ V + G+
Sbjct: 28 RTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV 87
Query: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGD---YAYVTEIFGGLAGFLLLWSAV---L 128
+ +++ + L +CYAE GV +PK+ G Y+YVT G F + W+ + L
Sbjct: 88 -IVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVT--VGEFVAFFIGWNLILEYL 144
Query: 129 IMYPTSLAVISMTF---SNYVLQPVFPNCIPPTTA--------SRVLSMACLMLLTWVNS 177
I + +S F +N+ + + + +L++ +++T + +
Sbjct: 145 IGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVA 204
Query: 178 SSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALA 237
V+ + ++ L I+ GL I ++ E + H
Sbjct: 205 LGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAE-----------GQFLPHGWSG 253
Query: 238 FLQGS----FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSP 293
LQG+ +AF G++ + EE + ++P AI S+ + Y ++ T M P
Sbjct: 254 VLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSV-ILTLMVP 312
Query: 294 QELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGIN----GYLFTYSRLCFSGAREGH 349
+ + + + E + + + VA+ + G+ G LF R+ ++ A +G
Sbjct: 313 YYTIDTESPLM---EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGL 369
Query: 350 LPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLL 409
L LA + TP+ A +V A++ L+ LI +S L Y + + +LLL
Sbjct: 370 LFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLL 429
Query: 410 RWR 412
R++
Sbjct: 430 RYQ 432
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 41.2 bits (95), Expect = 0.002
Identities = 80/384 (20%), Positives = 150/384 (39%), Gaps = 50/384 (13%)
Query: 41 GLLSACTIIIGNIIGSGIFISPKGVLEHSGSV-GLALFVWV-LGGGVTALGSLCYAELGV 98
G+ ++C I NI G +F+ ++ ++G + G+ L +V L VT L + E
Sbjct: 44 GVFTSCMI---NIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSS 100
Query: 99 AIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC-IPP 157
SGG Y+ ++ + GG G + ++Y V + + + +
Sbjct: 101 I--GSGGVYSMISSVLGGQTG-----GTIGLLYVFGQCVAGAMYITGFAESISDLLGLGN 153
Query: 158 TTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEEL 217
A R +S+A L+ L +N + V+W R+Q L L ++ V L G F L
Sbjct: 154 IWAVRGISVAVLLALLGINLAGVKWIIRLQ--------LLLLFLLAVSTLDFVVGSFTHL 205
Query: 218 RPSNAFAFWMTPSVGHLALA---------------FLQGSFAFSGWNFLNYVTEEMVDAR 262
P + F + + + L F + +G+N + E
Sbjct: 206 DPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIP 265
Query: 263 KNLPRAIFISIPL-VTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVS 321
A+ IS L + FV+ I A+ L++ L+G+ + +
Sbjct: 266 LGSLAAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKV-------SLMGF---LFLLG 315
Query: 322 VALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVR--HCTPIPALLVCCGATAVIM 379
+ +S+ G L+ R+ A+E +P+L + + + TP+ A+ + T +
Sbjct: 316 LYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFV 375
Query: 380 LVGDTYTLINYVSFINYLCYGVTI 403
VG L V+ IN++ V +
Sbjct: 376 FVGQVNVLAPIVT-INFMLTYVAV 398
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 493 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 551
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 552 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 611
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 612 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 659
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 499 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 557
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 558 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 617
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 618 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 665
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 449 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 567
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 568 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 615
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 449 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 567
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 568 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 615
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 457 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 515
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 516 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 575
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 576 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 623
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 37.4 bits (85), Expect = 0.034
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 508 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 566
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 567 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 626
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
+ +L+ + +S +CY L L R RP
Sbjct: 627 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 674
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 36.6 bits (83), Expect = 0.057
Identities = 56/269 (20%), Positives = 107/269 (39%), Gaps = 54/269 (20%)
Query: 41 GLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGV-A 99
G+L C + NI G +FI ++ +G +GL++ V ++ VT + L + +
Sbjct: 290 GVLVRCML---NIWGVMLFIRLSWIVGQAG-IGLSVLVIMMATVVTTITGLSTSAIATNG 345
Query: 100 IPKSGGDYAYVTEI----FGGLAGFLLLWS--AVLIMYPTSLA--VISMTFSNYVLQPVF 151
+ GG Y ++ FGG G + ++ + MY A V+ + + +L
Sbjct: 346 FVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILM--- 402
Query: 152 PNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALS-LIIGVGL---- 206
I R++ +++L ++ + + W + Q + LLA+ +IG +
Sbjct: 403 ---IDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLES 459
Query: 207 ----------LQIFQGHF-----EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFL 251
+IF +F EE + FA + + G LA A + G A
Sbjct: 460 KKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLA------- 512
Query: 252 NYVTEEMVDARKNLPRAIFISIPLVTFVY 280
D + +P+ ++I + T VY
Sbjct: 513 --------DPQSAIPKGTLLAILITTLVY 533
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 35.0 bits (79), Expect = 0.17
Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 6/148 (4%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
++ DA+K++P ++I +F+Y + I F A +L G ++G +W
Sbjct: 443 DLKDAQKSIPTGTILAIVTTSFIY-LSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAW 501
Query: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
P + + +F G L RL + AR+G +P L H + + P ALL+
Sbjct: 502 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLT 561
Query: 372 CGATAVIMLVGDTYTLINYVSFINYLCY 399
+L+ ++ +S +CY
Sbjct: 562 VLICETGILIASLDSVAPILSMFFLMCY 589
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 33.9 bits (76), Expect = 0.37
Identities = 46/208 (22%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFS- 315
E+ D + +P +++ FVY + +F LSS T ++ G+F
Sbjct: 290 ELKDPSRAIPLGTIVAVAYTFFVYV---LLFF--------LSSFTCDRTLLQEDYGFFRA 338
Query: 316 ---W--VMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHV--RHCTPIPAL 368
W ++ + + + L SR+ + AR+ +LA V R P A+
Sbjct: 339 ISLWPPLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAV 398
Query: 369 LVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPV 428
L G +++L G TL V+ + Y L L L W RP +L
Sbjct: 399 LYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRP-TFSLFSWH 457
Query: 429 AYLVFWAFLLVFSFISEPMVCGVGVIII 456
L+ A L+ F+ P G ++++
Sbjct: 458 TCLLGVASCLLMMFLISPGAAGGSLLLM 485
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,777,396
Number of Sequences: 37866
Number of extensions: 1057305
Number of successful extensions: 7394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 7285
Number of HSP's gapped (non-prelim): 83
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.