Guide to the Human Genome
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Search of human proteins with 93141226

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|93141226 X-prolyl aminopeptidase 2, membrane-bound [Homo
sapiens]
         (674 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|93141226 X-prolyl aminopeptidase 2, membrane-bound [Homo sapi...  1380   0.0  
gi|21359929 X-prolyl aminopeptidase (aminopeptidase P) 1, solubl...   492   e-139
gi|149589008 peptidase D [Homo sapiens]                                43   0.001
gi|11559925 X-prolyl aminopeptidase (aminopeptidase P) 3, putati...    43   0.001
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  34   0.50 
gi|62953127 polyhomeotic 1-like [Homo sapiens]                         31   3.3  
gi|157787091 UDP glucuronosyltransferase 2 family, polypeptide A...    31   4.3  
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]               30   9.5  

>gi|93141226 X-prolyl aminopeptidase 2, membrane-bound [Homo
           sapiens]
          Length = 674

 Score = 1380 bits (3572), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQ 60
           MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQ
Sbjct: 1   MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQ 60

Query: 61  MQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQ 120
           MQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQ
Sbjct: 61  MQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQ 120

Query: 121 AERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQL 180
           AERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQL
Sbjct: 121 AERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQL 180

Query: 181 VSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLS 240
           VSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLS
Sbjct: 181 VSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLS 240

Query: 241 ALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCV 300
           ALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCV
Sbjct: 241 ALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCV 300

Query: 301 QIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSK 360
           QIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSK
Sbjct: 301 QIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSK 360

Query: 361 EQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETIS 420
           EQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETIS
Sbjct: 361 EQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETIS 420

Query: 421 ASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYT 480
           ASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYT
Sbjct: 421 ASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYT 480

Query: 481 RVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQ 540
           RVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQ
Sbjct: 481 RVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQ 540

Query: 541 SNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNL 600
           SNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNL
Sbjct: 541 SNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNL 600

Query: 601 IDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWAS 660
           IDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWAS
Sbjct: 601 IDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWAS 660

Query: 661 VLVVSTLAILGWSV 674
           VLVVSTLAILGWSV
Sbjct: 661 VLVVSTLAILGWSV 674


>gi|21359929 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
           [Homo sapiens]
          Length = 623

 Score =  492 bits (1266), Expect = e-139
 Identities = 262/620 (42%), Positives = 384/620 (61%), Gaps = 25/620 (4%)

Query: 50  TTMSLTALRQQMQ-----TQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVV 104
           T+  L  LRQ M+     T+ + AYIIP  DAH +EYI   D RRA+++GF GSAGTA++
Sbjct: 6   TSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAII 65

Query: 105 TMKKAAVWTDSRYWTQAERQMDCNWELHKE-VGTTPIVT-WLLTEIPAGGRVGFDPFLLS 162
           T + AA+WTD RY+ QA +QMD NW L K  +  TP    WL++ +P G RVG DP ++ 
Sbjct: 66  TEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIP 125

Query: 163 IDTWESYDLALQGSNRQLVSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSG 222
            D W+     L+ +   L+ +  NLVD +W ++RP  P +P+  L   +TG +W++KV+ 
Sbjct: 126 TDYWKKMAKVLRSAGHHLIPVKENLVDKIW-TDRPERPCKPLLTLGLDYTGISWKDKVAD 184

Query: 223 VRSQMQKHQKVPTAVLLSALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRF 282
           +R +M +   +   V  +AL+E AWLFNLR SD+ +NP F+SY ++   +I LF +  R 
Sbjct: 185 LRLKMAERNVMWFVV--TALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRI 242

Query: 283 SSETLS---YLNSSCTGPMCVQIEDYSQVRDSIQAYSLG---DVRIWIGTSYTMYGIYEM 336
            + ++     L+        +Q+  Y  +   ++A         ++W+    + Y + E 
Sbjct: 243 DAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKAS-YAVSET 301

Query: 337 IPKEKLVTDTYSPVMMTKAVKNSKEQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFS 396
           IPK+      Y+P+ + KAVKNS E   ++ +H++DAVA+     WLEK VPKG V E S
Sbjct: 302 IPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEIS 361

Query: 397 GAEIVDKFRGEEQFSSGPSFETISASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYW 456
            A+  ++FR ++      SF TIS++G N A+ HY+P  E NR LS DE+YL+DSG QY 
Sbjct: 362 AADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYK 421

Query: 457 DGTTDITRTVHWGTPSAFQKEAYTRVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGL 516
           DGTTD+TRT+H+GTP+A++KE +T VL G+I +S  +FP  T G ++++FAR ALWD+GL
Sbjct: 422 DGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGL 481

Query: 517 NYGHGTGHGIGNFLCVHEWPVGFQSNNIA---MAKGMFTSIEPGYYKDGEFGIRLEDVAL 573
           +Y HGTGHG+G+FL VHE P G      +   +  GM  + EPGYY+DG FGIR+E+V L
Sbjct: 482 DYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVL 541

Query: 574 VVEAKTKY----PGSYLTFEVVSFVPYDRNLIDVSLLSPEHLQYLNRYYQTIREKVGPEL 629
           VV  KTKY     GS LTFE ++ VP    +IDV  L+ +   +LN Y+ T R+ +G EL
Sbjct: 542 VVPVKTKYNFNNRGS-LTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL 600

Query: 630 QRRQLLEEFEWLQQHTEPLA 649
           Q++   E  EWL + T+P++
Sbjct: 601 QKQGRQEALEWLIRETQPIS 620


>gi|149589008 peptidase D [Homo sapiens]
          Length = 493

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/224 (26%), Positives = 88/224 (39%), Gaps = 48/224 (21%)

Query: 415 SFETISASGLNAALAHYSPTKELN-RKLSSDEMYLLDSGGQYWDGTTDITRTVHW-GTPS 472
           S+  I  SG N+A+ HY      N R + + +M L D GG+Y+   +DIT +    G  +
Sbjct: 240 SYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFT 299

Query: 473 AFQKEAYTRVLIGNIDLSRLIFPAATSG-------RMVEAFARRALWDAGLNYGHGTG-- 523
           A QK  Y  VL      SR +  A   G       R+ +      L   G+  G      
Sbjct: 300 ADQKAVYEAVLRS----SRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMV 355

Query: 524 ----------HGIGNFLCVHEWPVGFQSNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVAL 573
                     HG+G+FL +    VG         +G+    EPG             +  
Sbjct: 356 QAHLGAVFMPHGLGHFLGIDVHDVG------GYPEGVERIDEPG-------------LRS 396

Query: 574 VVEAKTKYPGSYLTFEV-VSFVPYDRNLIDVSLLSPEHLQYLNR 616
           +  A+   PG  LT E  + F+ +   L+D +L  P    +LNR
Sbjct: 397 LRTARHLQPGMVLTVEPGIYFIDH---LLDEALADPARASFLNR 437


>gi|11559925 X-prolyl aminopeptidase (aminopeptidase P) 3, putative
           [Homo sapiens]
          Length = 507

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 40/193 (20%)

Query: 415 SFETISASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHW---GTP 471
           ++  + A G  +   HY    +L   +   EM LLD G +     +DITRT  W   G  
Sbjct: 299 AYPPVVAGGNRSNTLHYVKNNQL---IKDGEMVLLDGGCESSCYVSDITRT--WPVNGRF 353

Query: 472 SAFQKEAYTRVLIGNIDLSRLIFPAATSGR---MVEAFARRALWDAGLNYG--------- 519
           +A Q E Y  VL    D   L FP  +      M+     + L D G+            
Sbjct: 354 TAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKA 413

Query: 520 ------HGTGHGIGNFLCVHEWPVGFQSNNIAMAKGMFTSIEPGYY-----KDGE----- 563
                 H  GH +G  + VH+ P      ++ +  GM  +IEPG Y     KD       
Sbjct: 414 ARKYCPHHVGHYLG--MDVHDTP--DMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRG 469

Query: 564 FGIRLEDVALVVE 576
            G+R+ED  +V +
Sbjct: 470 LGVRIEDDVVVTQ 482


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 39   NPPYLPVTVVNTTMSLTALRQQMQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGS 98
            NP +LP    +  M+  AL Q  Q Q L  + IPGT+  +   +G        + G TG 
Sbjct: 1670 NPAFLP----HFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMTGM 1725

Query: 99   AGTAVVTMKK 108
            AG+ +  +K+
Sbjct: 1726 AGSLLEDLKQ 1735


>gi|62953127 polyhomeotic 1-like [Homo sapiens]
          Length = 1004

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 5/56 (8%)

Query: 24  KPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQMQTQNLSAYI-----IPGT 74
           KP  LG   +      PP++PV VV T    TA  Q +    L+A +     +PGT
Sbjct: 506 KPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGT 561


>gi|157787091 UDP glucuronosyltransferase 2 family, polypeptide A2
           [Homo sapiens]
          Length = 528

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 33/151 (21%), Positives = 66/151 (43%), Gaps = 13/151 (8%)

Query: 267 LLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCVQIEDYSQVRDSIQAYSLGDVRIWIG- 325
           ++ +  I+   N +  +S    ++NS+   P+  ++   S  + +I +     + +WI  
Sbjct: 39  IILEELIQRNHNVTVLASSATLFINSNPDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDH 98

Query: 326 --TSYTMYGIYEMIPKEKLVTDTYSPV---MMTKAVKNSKEQALLKASH----VRDAVAV 376
             T  T++  Y+ + K   + DT+  +   +    +KN K  A L+       V D V +
Sbjct: 99  RPTPLTIWAFYKELGK---LLDTFFQINIQLCDGVLKNPKLMARLQKGGFDVLVADPVTI 155

Query: 377 IRYLVWLEKNVPKGTVDEFSGAEIVDKFRGE 407
              LV L+  +P      FS A  V++  G+
Sbjct: 156 CGDLVALKLGIPFMYTLRFSPASTVERHCGK 186


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 29.6 bits (65), Expect = 9.5
 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 29/129 (22%)

Query: 372  DAVAVIRYLVWLEKNVPKGTVDEFSGAE-----IVDKFRGEEQFSSGPSFETISASGLNA 426
            D+   + +L+   +N+ K   DEF   +     ++D F      +S P    IS SG   
Sbjct: 1959 DSYMDVVFLIDNSRNIAK---DEFKAVKALVSSVIDNFN----IASDP---LISDSGDRI 2008

Query: 427  ALAHYSPTKELNRKLSS----------DEMYL----LDSGGQYWDGTTDITRTVHWGTPS 472
            AL  YSP +   RK+ +          D   L    + +  Q  +G   I R + W T +
Sbjct: 2009 ALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTEN 2068

Query: 473  AFQKEAYTR 481
             F +  Y R
Sbjct: 2069 LFPETPYLR 2077


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,003,414
Number of Sequences: 37866
Number of extensions: 1125670
Number of successful extensions: 2590
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2578
Number of HSP's gapped (non-prelim): 9
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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