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Search of human proteins with 91807119
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens]
(221 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens] 479 e-136
gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens] 465 e-131
gi|14042945 beta-amyloid binding protein precursor [Homo sapiens] 77 9e-15
gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens] 65 5e-11
gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens] 65 5e-11
gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens] 65 5e-11
gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens] 65 5e-11
gi|4504151 granulin precursor [Homo sapiens] 34 0.086
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 32 0.43
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 32 0.43
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 32 0.43
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 32 0.43
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 32 0.43
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 29 2.8
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 29 2.8
gi|31657140 insulin receptor-related receptor precursor [Homo sa... 28 4.7
gi|53828708 olfactory receptor, family 6, subfamily C, member 4 ... 28 8.1
gi|122937283 6720455I24Rik homolog [Homo sapiens] 28 8.1
>gi|91807119 TM2 domain containing 3 isoform b [Homo sapiens]
Length = 221
Score = 479 bits (1233), Expect = e-136
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MAGGVLPLRGLRALCRVLLFLSQFCILSGGESTEIPPYVMKCPSNGLCSRLPADCIDCTT 60
MAGGVLPLRGLRALCRVLLFLSQFCILSGGESTEIPPYVMKCPSNGLCSRLPADCIDCTT
Sbjct: 1 MAGGVLPLRGLRALCRVLLFLSQFCILSGGESTEIPPYVMKCPSNGLCSRLPADCIDCTT 60
Query: 61 NFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMT 120
NFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMT
Sbjct: 61 NFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMT 120
Query: 121 VSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYL 180
VSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYL
Sbjct: 121 VSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYL 180
Query: 181 GQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 221
GQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI
Sbjct: 181 GQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 221
>gi|91807117 TM2 domain containing 3 isoform a [Homo sapiens]
Length = 247
Score = 465 bits (1196), Expect = e-131
Identities = 221/247 (89%), Positives = 221/247 (89%), Gaps = 26/247 (10%)
Query: 1 MAGGVLPLRGLRALCRVLLFLSQFCILSGGE--------------------------STE 34
MAGGVLPLRGLRALCRVLLFLSQFCILSGGE STE
Sbjct: 1 MAGGVLPLRGLRALCRVLLFLSQFCILSGGEQSQALAQSIKDPGPTRTFTVVPRAAESTE 60
Query: 35 IPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFI 94
IPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFI
Sbjct: 61 IPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFI 120
Query: 95 INMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNW 154
INMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNW
Sbjct: 121 INMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNW 180
Query: 155 TGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGP 214
TGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGP
Sbjct: 181 TGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGP 240
Query: 215 ADGSLYI 221
ADGSLYI
Sbjct: 241 ADGSLYI 247
>gi|14042945 beta-amyloid binding protein precursor [Homo sapiens]
Length = 207
Score = 77.4 bits (189), Expect = 9e-15
Identities = 53/116 (45%), Positives = 65/116 (56%), Gaps = 12/116 (10%)
Query: 112 CTNSTSCMTVSCPRQRYPA-NCTVRD----HVHCLGNRT-FPKMLYCNWTGGYKWSTALA 165
CTN T+ VSC +PA N T +D H GN F K + C GY + A+A
Sbjct: 73 CTNYTA--HVSC----FPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVA 126
Query: 166 LSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 221
LS+ LG GADRFYLG GL K + G GI +LID +LI + VGP+DGS YI
Sbjct: 127 LSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYI 182
>gi|66932897 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 65.1 bits (157), Expect = 5e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 132 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 190
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 78 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 137
Query: 191 FSFGGLGIWTLIDVLLIGVGYVGPADGS 218
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 138 LTLGGLGIWWFVDLILLITGGLMPSDGS 165
>gi|66932895 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 65.1 bits (157), Expect = 5e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 132 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 190
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 78 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 137
Query: 191 FSFGGLGIWTLIDVLLIGVGYVGPADGS 218
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 138 LTLGGLGIWWFVDLILLITGGLMPSDGS 165
>gi|66932893 TM2 domain containing 2 isoform b [Homo sapiens]
Length = 171
Score = 65.1 bits (157), Expect = 5e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 132 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 190
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 78 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 137
Query: 191 FSFGGLGIWTLIDVLLIGVGYVGPADGS 218
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 138 LTLGGLGIWWFVDLILLITGGLMPSDGS 165
>gi|17865797 TM2 domain containing 2 isoform a [Homo sapiens]
Length = 214
Score = 65.1 bits (157), Expect = 5e-11
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 132 CTVRDHVHCLGNRTFPKMLY-CNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKL 190
C D + C RTF + C G+ + T L S LG FG DRF LG +GKL
Sbjct: 121 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 180
Query: 191 FSFGGLGIWTLIDVLLIGVGYVGPADGS 218
+ GGLGIW +D++L+ G + P+DGS
Sbjct: 181 LTLGGLGIWWFVDLILLITGGLMPSDGS 208
>gi|4504151 granulin precursor [Homo sapiens]
Length = 593
Score = 34.3 bits (77), Expect = 0.086
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 26/149 (17%)
Query: 25 CILSGGESTEI-PPYVMKCPSNGLCSRLPADC---IDCTTNFSCTYGKPVTFDCAVKP-S 79
C+ GG S P + K P+ L L C C+ SC + T C P +
Sbjct: 31 CLDPGGASYSCCRPLLDKWPTT-LSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEA 89
Query: 80 VTCVDQDFKSQKNFIINMTCRFCWQ-----------LPETDYECTN-STSCMTVS----- 122
V C D + F + R C+Q P++ +EC + ST C+ V
Sbjct: 90 VACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGC 149
Query: 123 CPRQRYPANCTVRDHVHCLGNRTFPKMLY 151
CP + A+C D VHC + F +++
Sbjct: 150 CPMPQ--ASC-CEDRVHCCPHGAFCDLVH 175
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 32.0 bits (71), Expect = 0.43
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 47 LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQD----FKSQKNFIIN-MTCRF 101
+C R+ DC + T + C +C + S C+ Q+ + S ++ N CR
Sbjct: 694 MCRRMVCDCENPTVDLFCCP------ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC 747
Query: 102 ------CWQLPETDYECTNSTSCMTVSCPR 125
CW LP D EC S CPR
Sbjct: 748 LQGEVDCWPLPCPDVECEFSILPENECCPR 777
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 32.0 bits (71), Expect = 0.43
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 47 LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQD----FKSQKNFIIN-MTCRF 101
+C R+ DC + T + C +C + S C+ Q+ + S ++ N CR
Sbjct: 670 MCRRMVCDCENPTVDLFCCP------ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC 723
Query: 102 ------CWQLPETDYECTNSTSCMTVSCPR 125
CW LP D EC S CPR
Sbjct: 724 LQGEVDCWPLPCPDVECEFSILPENECCPR 753
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 32.0 bits (71), Expect = 0.43
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 47 LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQD----FKSQKNFIIN-MTCRF 101
+C R+ DC + T + C +C + S C+ Q+ + S ++ N CR
Sbjct: 671 MCRRMVCDCENPTVDLFCCP------ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC 724
Query: 102 ------CWQLPETDYECTNSTSCMTVSCPR 125
CW LP D EC S CPR
Sbjct: 725 LQGEVDCWPLPCPDVECEFSILPENECCPR 754
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 32.0 bits (71), Expect = 0.43
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 47 LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQD----FKSQKNFIIN-MTCRF 101
+C R+ DC + T + C +C + S C+ Q+ + S ++ N CR
Sbjct: 721 MCRRMVCDCENPTVDLFCCP------ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC 774
Query: 102 ------CWQLPETDYECTNSTSCMTVSCPR 125
CW LP D EC S CPR
Sbjct: 775 LQGEVDCWPLPCPDVECEFSILPENECCPR 804
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 32.0 bits (71), Expect = 0.43
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 47 LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQD----FKSQKNFIIN-MTCRF 101
+C R+ DC + T + C +C + S C+ Q+ + S ++ N CR
Sbjct: 671 MCRRMVCDCENPTVDLFCCP------ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC 724
Query: 102 ------CWQLPETDYECTNSTSCMTVSCPR 125
CW LP D EC S CPR
Sbjct: 725 LQGEVDCWPLPCPDVECEFSILPENECCPR 754
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 29.3 bits (64), Expect = 2.8
Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 21/98 (21%)
Query: 31 ESTEIPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPS----VTCVD-- 84
E++E P ++CP + L S A +C F P + C PS +T V
Sbjct: 284 EASESP--CLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMG 341
Query: 85 ----------QDFKSQKNFIINMTCRFCWQLPETDYEC 112
QD +++ + ++TC CW PE+ EC
Sbjct: 342 AKVELRWTPPQDSGGREDIVYSVTCEQCW--PESG-EC 376
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 29.3 bits (64), Expect = 2.8
Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 22/112 (19%)
Query: 41 KCPSNGLCSRLPADCIDCTTNFSCTYG---KPVTFDCAV-------KPSVT--------C 82
+CP+ S C CT T +P F C V K S T C
Sbjct: 52 ECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQC 111
Query: 83 VDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTV 134
+ F+++ + CR C + P + + +N TS + C + + AN TV
Sbjct: 112 KEGTFRNENS---PEMCRKCSRCPSGEVQVSNCTSWDDIQCV-EEFGANATV 159
>gi|31657140 insulin receptor-related receptor precursor [Homo
sapiens]
Length = 1297
Score = 28.5 bits (62), Expect = 4.7
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 108 TDYECTNSTSCMTVSCPRQRYPANCTVRD---HVHCLGNRTFPK 148
TDY C S+ C V CP A CT R H CLG + P+
Sbjct: 200 TDYRCWTSSHCQRV-CPCPHGMA-CTARGECCHTECLGGCSQPE 241
>gi|53828708 olfactory receptor, family 6, subfamily C, member 4
[Homo sapiens]
Length = 309
Score = 27.7 bits (60), Expect = 8.1
Identities = 10/40 (25%), Positives = 21/40 (52%)
Query: 119 MTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGY 158
+ S RY A C ++ + +R ++++C+W GG+
Sbjct: 112 LLASMSYDRYVAICKPLHYLTIMSSRVCIQLVFCSWLGGF 151
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 27.7 bits (60), Expect = 8.1
Identities = 27/106 (25%), Positives = 34/106 (32%), Gaps = 37/106 (34%)
Query: 55 CIDCTTNFSC------------TYGKPVTFDCAVKP---SVTCVDQDFKSQKNFIINMTC 99
C+D N++C T PV C P TCVD D
Sbjct: 402 CVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD------------- 448
Query: 100 RFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRT 145
Y C M + C R+R P +C R+ CLG T
Sbjct: 449 --------QGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANT 485
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.143 0.491
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,777,231
Number of Sequences: 37866
Number of extensions: 464751
Number of successful extensions: 1086
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1067
Number of HSP's gapped (non-prelim): 25
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.