Guide to the Human Genome
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Search of human proteins with 14149981

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149981 transmembrane protein 117 [Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149981 transmembrane protein 117 [Homo sapiens]                 1068   0.0  
gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]            37   0.056
gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]            37   0.056
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    33   0.81 
gi|7706575 transmembrane 7 superfamily member 3 [Homo sapiens]         33   0.81 
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    32   1.4  
gi|19923572 SLAM family member 7 [Homo sapiens]                        31   2.4  
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             30   4.0  
gi|239746535 PREDICTED: hypothetical protein XP_002343755 [Homo ...    30   5.3  
gi|93204867 G protein-coupled receptor 158 [Homo sapiens]              30   5.3  
gi|112363092 RING1 and YY1 binding protein [Homo sapiens]              30   6.9  
gi|194239697 solute carrier family 1 (glutamate transporter), me...    29   9.0  
gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]        29   9.0  

>gi|14149981 transmembrane protein 117 [Homo sapiens]
          Length = 514

 Score = 1068 bits (2762), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPR 60
           MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPR
Sbjct: 1   MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPR 60

Query: 61  GVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLF 120
           GVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLF
Sbjct: 61  GVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLF 120

Query: 121 IFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKP 180
           IFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKP
Sbjct: 121 IFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKP 180

Query: 181 YPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA 240
           YPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA
Sbjct: 181 YPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA 240

Query: 241 FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITG 300
           FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITG
Sbjct: 241 FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITG 300

Query: 301 KWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWE 360
           KWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWE
Sbjct: 301 KWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWE 360

Query: 361 WRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKN 420
           WRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKN
Sbjct: 361 WRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKN 420

Query: 421 EPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKS 480
           EPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKS
Sbjct: 421 EPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKS 480

Query: 481 SHLTSENLSSQLNESTSATEADQDPTTSKSTPTN 514
           SHLTSENLSSQLNESTSATEADQDPTTSKSTPTN
Sbjct: 481 SHLTSENLSSQLNESTSATEADQDPTTSKSTPTN 514


>gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 11/105 (10%)

Query: 419 KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVY 478
           +++P    QD++    +R  P++  +D  I     Q+   D + D S+   +SD  +++ 
Sbjct: 275 QSDPTDVMQDQSIATAQRSDPTDVMQDQSIA--TAQSDPTDVMQDQSIATAQSDPTDVMQ 332

Query: 479 KSSHLTSENLSSQLNESTSATEADQDPT---------TSKSTPTN 514
             S  T+++  + + +  S   A  DPT         T++S PT+
Sbjct: 333 DRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 377



 Score = 29.3 bits (64), Expect = 9.0
 Identities = 23/105 (21%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 419 KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVY 478
           +++P    QD++    +   P++  +D  I     Q+   D + D S+   +SD  +++ 
Sbjct: 308 QSDPTDVMQDQSIATAQ-SDPTDVMQDRSIA--TAQSDPTDVMQDRSIATAQSDPTDVMQ 364

Query: 479 KSSHLTSENLSSQLNESTSATEADQDPT---------TSKSTPTN 514
             S  T+++  + + +  S   A  DPT         T++S PT+
Sbjct: 365 DRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 409


>gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 11/105 (10%)

Query: 419 KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVY 478
           +++P    QD++    +R  P++  +D  I     Q+   D + D S+   +SD  +++ 
Sbjct: 275 QSDPTDVMQDQSIATAQRSDPTDVMQDQSIA--TAQSDPTDVMQDQSIATAQSDPTDVMQ 332

Query: 479 KSSHLTSENLSSQLNESTSATEADQDPT---------TSKSTPTN 514
             S  T+++  + + +  S   A  DPT         T++S PT+
Sbjct: 333 DRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 377



 Score = 29.3 bits (64), Expect = 9.0
 Identities = 23/105 (21%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 419 KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVY 478
           +++P    QD++    +   P++  +D  I     Q+   D + D S+   +SD  +++ 
Sbjct: 308 QSDPTDVMQDQSIATAQ-SDPTDVMQDRSIA--TAQSDPTDVMQDRSIATAQSDPTDVMQ 364

Query: 479 KSSHLTSENLSSQLNESTSATEADQDPT---------TSKSTPTN 514
             S  T+++  + + +  S   A  DPT         T++S PT+
Sbjct: 365 DRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 409


>gi|4503647 coagulation factor VIII isoform a precursor [Homo
           sapiens]
          Length = 2351

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 32/138 (23%), Positives = 50/138 (36%), Gaps = 8/138 (5%)

Query: 341 YTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPS 400
           Y  +    L   +R  + W      T P  +  ++EG  FL      ASL++  + F+ +
Sbjct: 256 YVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTA 315

Query: 401 LIAFVWFGFFIWFFGRFLKNEPRMEN-------QDKTYTRMKRKSPSEHSKDMGITRENT 453
               +  G F+ F          ME         ++   RMK    +E   D  +T    
Sbjct: 316 QTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDYDD-DLTDSEM 374

Query: 454 QASVEDPLNDPSLVCIRS 471
                D  N PS + IRS
Sbjct: 375 DVVRFDDDNSPSFIQIRS 392


>gi|7706575 transmembrane 7 superfamily member 3 [Homo sapiens]
          Length = 570

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 7/119 (5%)

Query: 24  FFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILTGLIAG 83
           FF  LI    P+ +        V G+    V   +   V WR   + + +L +  GL+ G
Sbjct: 331 FFYILITRLTPIKYDVNLILTAVTGS----VGGMFLVAVWWRFGILSICMLCV--GLVLG 384

Query: 84  KFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTI-LLMDGNMGAYII 141
             +     F  L  LK+F +D   W+T     IL   +F      + +L  G +G+Y +
Sbjct: 385 FLISSVTFFTPLGNLKIFHDDGVFWVTFSCIAILIPVVFMGCLRILNILTCGVIGSYSV 443


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 419  KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRE-NTQASVEDPLNDPSLVCIRSDFNEIV 477
            K E +   +DK  ++ K KS  EHSK+   +R  + + S+ + L + +L   R D N+  
Sbjct: 1241 KAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSND-- 1298

Query: 478  YKSSHLTSENLSSQLNE 494
             K S ++S++ + +  E
Sbjct: 1299 -KISEVSSDSFTDRGQE 1314


>gi|19923572 SLAM family member 7 [Homo sapiens]
          Length = 335

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 11/82 (13%)

Query: 388 ASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEPRMEN-QDKTYTRMKRKSPS------ 440
           +S+ + CL  VP L++    G F+W    FLK E + E  ++K    + R++P+      
Sbjct: 224 SSMVLLCLLLVPLLLSLFVLGLFLW----FLKRERQEEYIEEKKRVDICRETPNICPHSG 279

Query: 441 EHSKDMGITRENTQASVEDPLN 462
           E+++   I   N     EDP N
Sbjct: 280 ENTEYDTIPHTNRTILKEDPAN 301


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 16/90 (17%)

Query: 421 EPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVE-------DPLNDPSLVCIRSDF 473
           E   E ++   + ++   PSE S +   +R NT+ +VE        P   PSL       
Sbjct: 715 EASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLA------ 768

Query: 474 NEIVYKSSHLTSENLSSQLNESTSATEADQ 503
              V  +     E++ +Q+N+S SA  A+Q
Sbjct: 769 ---VPSTKPAEDESVETQVNDSISAETAEQ 795


>gi|239746535 PREDICTED: hypothetical protein XP_002343755 [Homo
           sapiens]
          Length = 370

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 23/105 (21%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 419 KNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVY 478
           +++P    QD++    +   P++  +D  I     Q+   D + D S+   +SD  +++ 
Sbjct: 259 QSDPMDVMQDRSIATAQ-SDPTDVMQDRSIA--TAQSDPTDVMQDRSIATAQSDPTDVMQ 315

Query: 479 KSSHLTSENLSSQLNESTSATEADQDPT---------TSKSTPTN 514
             S  T+++  + + +  S   A  DPT         T++S PT+
Sbjct: 316 DQSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 360



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 11/95 (11%)

Query: 429 KTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENL 488
           KT     +  P +  +D  I     Q+   D + D S+   +SD  +++   S  T+++ 
Sbjct: 220 KTSIATAQSDPMDVMQDQSIA--TAQSDPTDVMQDQSIATAQSDPMDVMQDRSIATAQSD 277

Query: 489 SSQLNESTSATEADQDPT---------TSKSTPTN 514
            + + +  S   A  DPT         T++S PT+
Sbjct: 278 PTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTD 312


>gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
          Length = 1215

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 18/81 (22%)

Query: 432 TRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSSQ 491
           T + RK+P E S + G ++E T  +                      K SH T +++  Q
Sbjct: 785 TALIRKNPPESSGNTGKSKEETLKN-----------------RVFSLKKSHSTYDHVRDQ 827

Query: 492 LNESTS-ATEADQDPTTSKST 511
             ES+S  TE+ ++ TT  ST
Sbjct: 828 TEESSSLPTESQEEETTENST 848


>gi|112363092 RING1 and YY1 binding protein [Homo sapiens]
          Length = 228

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 418 LKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIV 477
           LK+ P   N  ++     + S + H+    +   +   + +  +   ++  I +DF E  
Sbjct: 118 LKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKT 177

Query: 478 YKSSH----LTSENLSSQLNESTSATEADQDPTTSKSTP 512
             SS     +TS   S Q N+S+S +E+    ++  STP
Sbjct: 178 RSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTP 216


>gi|194239697 solute carrier family 1 (glutamate transporter),
           member 7 [Homo sapiens]
          Length = 560

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 116 ILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMM 175
           +L +  FS     +L   G+ GA +++ +    NES MK+ AV  W   F   +++   +
Sbjct: 222 VLGIVFFSATMGIMLGRMGDSGAPLVS-FCQCLNESVMKIVAVAVWYFPFGIVFLIAGKI 280

Query: 176 LQ 177
           L+
Sbjct: 281 LE 282


>gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]
          Length = 502

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 15/130 (11%)

Query: 268 DVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKP 327
           D NL G    H    I FF   FK +Y+I+I G    Y + +L L+ D  + K    Y  
Sbjct: 343 DENLYGPIVKH----ISFFD-FFKHKYQINIDGTVAAYRLPYL-LVGDSVVLKQDSIYYE 396

Query: 328 HEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIG 387
           H Y + + P +    VK   +L DL   KL W   +   +    K    G  F  +  +G
Sbjct: 397 HFYNE-LQPWKHYIPVK--SNLSDL-LEKLKW---AKDHDEEAKKIAKAGQEFARNNLMG 449

Query: 388 ASLDVKCLAF 397
              D+ C  F
Sbjct: 450 D--DIFCYYF 457


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,956,719
Number of Sequences: 37866
Number of extensions: 790883
Number of successful extensions: 2462
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2438
Number of HSP's gapped (non-prelim): 26
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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