Search of human proteins with 7661996

Search of human proteins with 7661996

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo
sapiens]
         (370 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo sapi...   767   0.0  
gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo sa...    68   1e-11
gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo sa...    68   1e-11
gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo...    65   1e-10
gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo ...    46   5e-05
gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo...    42   0.001
gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo ...    42   0.001
gi|5032099 smoothened [Homo sapiens]                                   31   1.6  
gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo...    31   1.6  
gi|189491763 cytochrome P450, family 1, subfamily B, polypeptide...    30   3.5  
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s...    29   5.9  
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s...    29   5.9  
gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens]         29   7.7  

>gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo
           sapiens]
          Length = 370

 Score =  767 bits (1980), Expect = 0.0
 Identities = 370/370 (100%), Positives = 370/370 (100%)

Query: 1   MAITLEEAPWLGWLLVKALMRFAFMVVNNLVAIPSYICYVIILQPLRVLDSKRFWYIEGI 60
           MAITLEEAPWLGWLLVKALMRFAFMVVNNLVAIPSYICYVIILQPLRVLDSKRFWYIEGI
Sbjct: 1   MAITLEEAPWLGWLLVKALMRFAFMVVNNLVAIPSYICYVIILQPLRVLDSKRFWYIEGI 60

Query: 61  MYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLV 120
           MYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLV
Sbjct: 61  MYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLV 120

Query: 121 VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV 180
           VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV
Sbjct: 121 VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV 180

Query: 181 LFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAK 240
           LFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAK
Sbjct: 181 LFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAK 240

Query: 241 ELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLT 300
           ELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLT
Sbjct: 241 ELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLT 300

Query: 301 TWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYN 360
           TWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYN
Sbjct: 301 TWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYN 360

Query: 361 IIQYFYHCLF 370
           IIQYFYHCLF
Sbjct: 361 IIQYFYHCLF 370


>gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo
           sapiens]
          Length = 414

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 79/326 (24%), Positives = 125/326 (38%), Gaps = 46/326 (14%)

Query: 55  WYIEGIMYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCL 114
           W    ++  WL   VA      G  V+  G+    V  + +V+++NH+   D   L  CL
Sbjct: 79  WINNRLVATWLTLPVALLETMFGVKVIITGDAF--VPGERSVIIMNHRTRMDWMFLWNCL 136

Query: 115 QDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRS- 173
                +  + + L   +     FG         FI   R ++D      K H E+     
Sbjct: 137 MRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIH--RKWKDD-----KSHFEDMIDYF 189

Query: 174 ---RDRKWIVLFPEGGFLRKRRET-SQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQ 229
               +   +++FPEG  L +  ++ S AFA+KN L     V  PR+     +++ L    
Sbjct: 190 CDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRL---- 245

Query: 230 KNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPI 289
                          + K L  + D T+AYP   P   +  +L    P   H H   +PI
Sbjct: 246 --------------REGKNLDAVHDITVAYPHNIP-QSEKHLLQGDFPREIHFHVHRYPI 290

Query: 290 KDVPLETDDLTTWLYQRFVEKEDLLSHFYE-------TG--AFPPSKGHKEAVSREMTLS 340
             +P   +DL  W ++R+ EKE+ L  FY+       TG    PP K     +  ++   
Sbjct: 291 DTLPTSKEDLQLWCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSI 350

Query: 341 NLWIFLIQSFAFL----SGYMWYNII 362
             W     +   L    S   WY II
Sbjct: 351 LYWTLFSPAMCLLIYLYSLVKWYFII 376


>gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo
           sapiens]
          Length = 376

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 79/326 (24%), Positives = 125/326 (38%), Gaps = 46/326 (14%)

Query: 55  WYIEGIMYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCL 114
           W    ++  WL   VA      G  V+  G+    V  + +V+++NH+   D   L  CL
Sbjct: 41  WINNRLVATWLTLPVALLETMFGVKVIITGDAF--VPGERSVIIMNHRTRMDWMFLWNCL 98

Query: 115 QDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRS- 173
                +  + + L   +     FG         FI   R ++D      K H E+     
Sbjct: 99  MRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIH--RKWKDD-----KSHFEDMIDYF 151

Query: 174 ---RDRKWIVLFPEGGFLRKRRET-SQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQ 229
               +   +++FPEG  L +  ++ S AFA+KN L     V  PR+     +++ L    
Sbjct: 152 CDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRL---- 207

Query: 230 KNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPI 289
                          + K L  + D T+AYP   P   +  +L    P   H H   +PI
Sbjct: 208 --------------REGKNLDAVHDITVAYPHNIP-QSEKHLLQGDFPREIHFHVHRYPI 252

Query: 290 KDVPLETDDLTTWLYQRFVEKEDLLSHFYE-------TG--AFPPSKGHKEAVSREMTLS 340
             +P   +DL  W ++R+ EKE+ L  FY+       TG    PP K     +  ++   
Sbjct: 253 DTLPTSKEDLQLWCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSI 312

Query: 341 NLWIFLIQSFAFL----SGYMWYNII 362
             W     +   L    S   WY II
Sbjct: 313 LYWTLFSPAMCLLIYLYSLVKWYFII 338


>gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo
           sapiens]
          Length = 364

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/259 (23%), Positives = 109/259 (42%), Gaps = 42/259 (16%)

Query: 75  YAGYTVMEWGEDIKAVSKDEAVMLVNHQATGD--VCTLMMCLQDKGLVVAQMMWLMDHIF 132
           Y G  ++ +G+  K  +K+  + L NHQ+T D  V  ++   Q+    +  + +++    
Sbjct: 69  YTGVQILLYGDLPK--NKENIIYLANHQSTVDWIVADILAIRQN---ALGHVRYVLKEGL 123

Query: 133 KYTN-FGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKR 191
           K+   +G     HG  ++++   + ++++   +  L++   +    ++V+FPEG      
Sbjct: 124 KWLPLYGCYFAQHGGIYVKRSAKFNEKEM---RNKLQSYVDAGTPMYLVIFPEGTRYNPE 180

Query: 192 R----ETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKSK 247
           +      SQAFA +  L  L +V  PR  AT +                      D    
Sbjct: 181 QTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAF--------------------DCMKN 220

Query: 248 GLQWIIDTTIAYP------KAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLTT 301
            L  I D T+ Y       +       T  L    P + H+H      KDVP E + +  
Sbjct: 221 YLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKI-HIHIDRIDKKDVPEEQEHMRR 279

Query: 302 WLYQRFVEKEDLLSHFYET 320
           WL++RF  K+ +L  FYE+
Sbjct: 280 WLHERFEIKDKMLIEFYES 298


>gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo
           sapiens]
          Length = 378

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 25/159 (15%)

Query: 187 FLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAKELDSKS 246
           F  K+ E S   A+   LP L +  LPR+    I + +L    +N   A           
Sbjct: 180 FTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSL----RNVVSA----------- 224

Query: 247 KGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLTTWLYQR 306
                + D T+ +   E   +   + G  K     ++ R  P++D+P + D+ + WL++ 
Sbjct: 225 -----VYDCTLNFRNNENPTLLGVLNG--KKYHADLYVRRIPLEDIPEDDDECSAWLHKL 277

Query: 307 FVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIF 345
           + EK+     +Y TG FP +        R  TL N W+F
Sbjct: 278 YQEKDAFQEEYYRTGTFPETP--MVPPRRPWTLVN-WLF 313


>gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 68/302 (22%), Positives = 118/302 (39%), Gaps = 46/302 (15%)

Query: 66  LGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGD-VCTLMMC----LQDKGLV 120
           L M+  W      T+      ++   K+ AV+++NH    D +C   MC    +     V
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV 180
           +A+   L   +  +T + +  +    F  R+    RD  +  L++  +      +  W +
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIV----FCKRKWEEDRDTVVEGLRRLSDYP----EYMWFL 172

Query: 181 LFPEGG-FLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDA 239
           L+ EG  F   +   S   A    LP L    LPR+      +  L      G+ A    
Sbjct: 173 LYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCL-----RGTVAA--- 224

Query: 240 KELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILG--YRKPTVTHVHYRIFPIKDVPLETD 297
                       + D T+ +   +       +LG  Y K     +  R FP++D+PL+  
Sbjct: 225 ------------VYDVTLNFRGNK----NPSLLGILYGKKYEADMCVRRFPLEDIPLDEK 268

Query: 298 DLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNL--W--IFLIQSFAFL 353
           +   WL++ + EK+ L   + + G FP  +   +   R  TL N   W  I L   F+F+
Sbjct: 269 EAAQWLHKLYQEKDALQEIYNQKGMFPGEQ--FKPARRPWTLLNFLSWATILLSPLFSFV 326

Query: 354 SG 355
            G
Sbjct: 327 LG 328


>gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 68/302 (22%), Positives = 118/302 (39%), Gaps = 46/302 (15%)

Query: 66  LGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGD-VCTLMMC----LQDKGLV 120
           L M+  W      T+      ++   K+ AV+++NH    D +C   MC    +     V
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV 180
           +A+   L   +  +T + +  +    F  R+    RD  +  L++  +      +  W +
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIV----FCKRKWEEDRDTVVEGLRRLSDYP----EYMWFL 172

Query: 181 LFPEGG-FLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDA 239
           L+ EG  F   +   S   A    LP L    LPR+      +  L      G+ A    
Sbjct: 173 LYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCL-----RGTVAA--- 224

Query: 240 KELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILG--YRKPTVTHVHYRIFPIKDVPLETD 297
                       + D T+ +   +       +LG  Y K     +  R FP++D+PL+  
Sbjct: 225 ------------VYDVTLNFRGNK----NPSLLGILYGKKYEADMCVRRFPLEDIPLDEK 268

Query: 298 DLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNL--W--IFLIQSFAFL 353
           +   WL++ + EK+ L   + + G FP  +   +   R  TL N   W  I L   F+F+
Sbjct: 269 EAAQWLHKLYQEKDALQEIYNQKGMFPGEQ--FKPARRPWTLLNFLSWATILLSPLFSFV 326

Query: 354 SG 355
            G
Sbjct: 327 LG 328


>gi|5032099 smoothened [Homo sapiens]
          Length = 787

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 331 EAVSREMTLSNLWIFLIQSFAFLSGYMWYNIIQYFYHCLF 370
           E  S E TLS + IF+I  +A ++G +W+ ++ Y +H  F
Sbjct: 305 EPTSNE-TLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF 343


>gi|155969714 nuclear protein,  ataxia-telangiectasia locus [Homo
           sapiens]
          Length = 1427

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 184 EGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSP 234
           +GG+++    TS AF   NN+   T VT P +  T +  + +V    N +P
Sbjct: 846 DGGYIQLMPATSTAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAP 896


>gi|189491763 cytochrome P450, family 1, subfamily B, polypeptide 1
           [Homo sapiens]
          Length = 543

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 18/78 (23%), Positives = 37/78 (47%)

Query: 269 TWILGYRKPTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKG 328
           T +LGY  P  T V    + +   PL+  +   +   RF++K+ L++    +     S G
Sbjct: 407 TSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVG 466

Query: 329 HKEAVSREMTLSNLWIFL 346
            +  +  E++   L++F+
Sbjct: 467 KRRCIGEELSKMQLFLFI 484


>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
           sapiens]
          Length = 970

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 115 QDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRS- 173
           QD+      MM     IF   + G++  V   FFI   RS+R + LLL +    N YRS 
Sbjct: 482 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSI 541

Query: 174 RDRKWIVLFP 183
            D + I+  P
Sbjct: 542 NDYREIITIP 551


>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
           sapiens]
          Length = 865

 Score = 29.3 bits (64), Expect = 5.9
 Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 115 QDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRS- 173
           QD+      MM     IF   + G++  V   FFI   RS+R + LLL +    N YRS 
Sbjct: 377 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSI 436

Query: 174 RDRKWIVLFP 183
            D + I+  P
Sbjct: 437 NDYREIITIP 446


>gi|4757962 cyclin-dependent kinase inhibitor 1B [Homo sapiens]
          Length = 198

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 15/123 (12%)

Query: 163 LKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLP-FLTNVTLPRSGATKII 221
           L+KH  +   +  RKW   F     L  + E  +   +K +LP F      P  GA K+ 
Sbjct: 45  LEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEV--EKGSLPEFYYRPPRPPKGACKV- 101

Query: 222 LNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWI----LGYRKP 277
             A  +Q  +GS          + S+      DT +  PK +P D QT +     G RK 
Sbjct: 102 -PAQESQDVSGSRPAAPLIGAPANSE------DTHLVDPKTDPSDSQTGLAEQCAGIRKR 154

Query: 278 TVT 280
             T
Sbjct: 155 PAT 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,902,916
Number of Sequences: 37866
Number of extensions: 591825
Number of successful extensions: 1539
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1524
Number of HSP's gapped (non-prelim): 14
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.