Search of human proteins with 7661872

Search of human proteins with 7661872

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor
[Homo sapiens]
         (903 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho...  1858   0.0  
gi|5454158 valyl-tRNA synthetase [Homo sapiens]                        77   7e-14
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]      67   6e-11
gi|94721239 isoleucine tRNA synthetase [Homo sapiens]                  65   3e-10
gi|94721241 isoleucine tRNA synthetase [Homo sapiens]                  65   3e-10
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]    61   4e-09
gi|108773810 leucyl-tRNA synthetase [Homo sapiens]                     49   2e-05
gi|14043022 methionyl-tRNA synthetase [Homo sapiens]                   38   0.037
gi|239747673 PREDICTED: doublecortin domain-containing protein E...    36   0.18 
gi|239741542 PREDICTED: doublecortin domain-containing protein E...    36   0.18 
gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo sap...    32   2.0  
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]      32   2.7  
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    31   4.5  
gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]     31   5.9  
gi|197100773 arginyl-tRNA synthetase 2, mitochondrial precursor ...    30   7.8  

>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
           sapiens]
          Length = 903

 Score = 1858 bits (4813), Expect = 0.0
 Identities = 903/903 (100%), Positives = 903/903 (100%)

Query: 1   MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE 60
           MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE
Sbjct: 1   MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE 60

Query: 61  KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM 120
           KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM
Sbjct: 61  KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM 120

Query: 121 QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD 180
           QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD
Sbjct: 121 QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD 180

Query: 181 YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ 240
           YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ
Sbjct: 181 YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ 240

Query: 241 WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT 300
           WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT
Sbjct: 241 WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT 300

Query: 301 ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI 360
           ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI
Sbjct: 301 ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI 360

Query: 361 LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ 420
           LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ
Sbjct: 361 LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ 420

Query: 421 DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT 480
           DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT
Sbjct: 421 DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT 480

Query: 481 LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH 540
           LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH
Sbjct: 481 LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH 540

Query: 541 SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK 600
           SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK
Sbjct: 541 SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK 600

Query: 601 GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID 660
           GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID
Sbjct: 601 GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID 660

Query: 661 TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK 720
           TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK
Sbjct: 661 TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK 720

Query: 721 EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA 780
           EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA
Sbjct: 721 EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA 780

Query: 781 LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ 840
           LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ
Sbjct: 781 LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ 840

Query: 841 MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL 900
           MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL
Sbjct: 841 MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL 900

Query: 901 VQD 903
           VQD
Sbjct: 901 VQD 903


>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
          Length = 1264

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 96/453 (21%), Positives = 167/453 (36%), Gaps = 54/453 (11%)

Query: 62  WWHQR--IKEQASKISEADKSKPKFYVLSMFPYPS--GKLHMGHVRVYTISDTIARFQKM 117
           WW Q+   K +  +      + P+   +   P P+  G LH+GH     I D++ R+ +M
Sbjct: 312 WWEQQGFFKPEYGR-PNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRM 370

Query: 118 RGMQVINPMGWDAFGLPAENAAVERNLHPQS------------------WTQSNIKHMRK 159
           RG   +   G D  G+ A    VE+ L  +                   W +     +  
Sbjct: 371 RGETTLWNPGCDHAGI-ATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYH 429

Query: 160 QLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQ 219
           QL +LG    WDR   T  P         F++L+E G+ Y+   LVNW     + +++ +
Sbjct: 430 QLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIE 489

Query: 220 VDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD---------LPEWYGIKGMQA 270
           VD+   + R+   V     +  F    ++A  +Q + +D         +    G   +  
Sbjct: 490 VDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAV 549

Query: 271 HWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEA 330
           H   D    HL     +H   +      +    +  +GT  V I+P+H         +  
Sbjct: 550 H-PKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHG 608

Query: 331 LR-MALVPGKDCL----TPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTI 385
           L  ++++  +  L     P + +     ++  +V L +  L   +           ED  
Sbjct: 609 LEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGI-----------EDNP 657

Query: 386 LAQTLGLAYSEVIETL--PDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDK 443
           +   L     +V+E L  P    R    A+          L +  +A  +        D 
Sbjct: 658 MVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRT--WHAWMDN 715

Query: 444 LKDWLISRQRYWGTPIPIVHCPVCGPTPVPLED 476
           +++W ISRQ +WG  IP     V  P   P ED
Sbjct: 716 IREWCISRQLWWGHRIPAYFVTVSDPAVPPGED 748


>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 1063

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 44/149 (29%), Positives = 68/149 (45%), Gaps = 19/149 (12%)

Query: 91  PYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQ--- 147
           P  +G LH+GH     I D + R+ +MRG QV+   G D  G+ A  A VE+ L  +   
Sbjct: 146 PNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGI-ATQAVVEKQLWKERGV 204

Query: 148 ---------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKL 192
                           W ++    + +QL  LG    WDRE  T            F++L
Sbjct: 205 RRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAVTEAFVRL 264

Query: 193 YEAGLAYQKEALVNWDPVDQTVLANEQVD 221
           Y+AGL Y+   LVNW    ++ +++ +V+
Sbjct: 265 YKAGLLYRNHQLVNWSCALRSAISDIEVE 293


>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 22/185 (11%)

Query: 51  YTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDT 110
           +  +  K +E W      ++  K S   K KPKF      P+ +G  H GH+   TI D 
Sbjct: 11  FPAEEEKILEFWTEFNCFQECLKQS---KHKPKFTFYDGPPFATGLPHYGHILAGTIKDI 67

Query: 111 IARFQKMRGMQVINPMGWDAFGLPAENAAVERNL---HPQSWTQSNIKHMRKQ------- 160
           + R+    G  V    GWD  GLP E   +++ L    P+   +  I     Q       
Sbjct: 68  VTRYAHQSGFHVDRRFGWDCHGLPVE-YEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMR 126

Query: 161 --------LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQ 212
                   + RLG    +D +  T  P + +   ++F +LY+ GL Y+   ++ +     
Sbjct: 127 YSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACN 186

Query: 213 TVLAN 217
           T L+N
Sbjct: 187 TPLSN 191



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 55/229 (24%), Positives = 83/229 (36%), Gaps = 59/229 (25%)

Query: 445 KDWLISRQRYWGTPIPI-----VHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMAS 499
           +DW ISR RYWGTPIP+         VC  +   LE+L  +   I+    +    L + S
Sbjct: 453 RDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEEL--SGAKISDLHRESVDHLTIPS 510

Query: 500 EWVNCSCPRC-KGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYI 558
                   RC KG+  R ++  D + +S      Y   H P    N    +   P D   
Sbjct: 511 --------RCGKGSLHRISEVFDCWFESG--SMPYAQVHYPFE--NKREFEDAFPADFIA 558

Query: 559 GGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVD 618
            G +      +     +     Q       PF  ++  GL+                   
Sbjct: 559 EGIDQTRGWFYTLLVLATALFGQ------PPFKNVIVNGLV------------------- 593

Query: 619 LTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYIL 667
                         L    +KMSK K N  DP  ++++YG D +RLY++
Sbjct: 594 --------------LASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628


>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 22/185 (11%)

Query: 51  YTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDT 110
           +  +  K +E W      ++  K S   K KPKF      P+ +G  H GH+   TI D 
Sbjct: 11  FPAEEEKILEFWTEFNCFQECLKQS---KHKPKFTFYDGPPFATGLPHYGHILAGTIKDI 67

Query: 111 IARFQKMRGMQVINPMGWDAFGLPAENAAVERNL---HPQSWTQSNIKHMRKQ------- 160
           + R+    G  V    GWD  GLP E   +++ L    P+   +  I     Q       
Sbjct: 68  VTRYAHQSGFHVDRRFGWDCHGLPVE-YEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMR 126

Query: 161 --------LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQ 212
                   + RLG    +D +  T  P + +   ++F +LY+ GL Y+   ++ +     
Sbjct: 127 YSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACN 186

Query: 213 TVLAN 217
           T L+N
Sbjct: 187 TPLSN 191



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 55/229 (24%), Positives = 83/229 (36%), Gaps = 59/229 (25%)

Query: 445 KDWLISRQRYWGTPIPI-----VHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMAS 499
           +DW ISR RYWGTPIP+         VC  +   LE+L  +   I+    +    L + S
Sbjct: 453 RDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEEL--SGAKISDLHRESVDHLTIPS 510

Query: 500 EWVNCSCPRC-KGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYI 558
                   RC KG+  R ++  D + +S      Y   H P    N    +   P D   
Sbjct: 511 --------RCGKGSLHRISEVFDCWFESG--SMPYAQVHYPFE--NKREFEDAFPADFIA 558

Query: 559 GGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVD 618
            G +      +     +     Q       PF  ++  GL+                   
Sbjct: 559 EGIDQTRGWFYTLLVLATALFGQ------PPFKNVIVNGLV------------------- 593

Query: 619 LTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYIL 667
                         L    +KMSK K N  DP  ++++YG D +RLY++
Sbjct: 594 --------------LASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628


>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
          Length = 1012

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 13/156 (8%)

Query: 79  KSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAE-- 136
           K K +F +    PY +G  H+GH     + D   RF  M G ++    GWD  GLP E  
Sbjct: 104 KVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIK 163

Query: 137 -----------NAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWT 185
                       +A+E     +S+ ++ I+  +    R G+   W+    T    Y    
Sbjct: 164 VLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQ 223

Query: 186 QYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVD 221
              F ++Y+ GL Y+    V W P  +T LA  +++
Sbjct: 224 LRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELE 259



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 13/22 (59%), Positives = 15/22 (68%)

Query: 442 DKLKDWLISRQRYWGTPIPIVH 463
           D+   W ISRQR WG PIP+ H
Sbjct: 515 DRRPYWCISRQRVWGVPIPVFH 536


>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
          Length = 1176

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 23/80 (28%), Positives = 42/80 (52%)

Query: 60  EKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRG 119
           +KW  +R+ E  +   E   SK K++V   +PY +G+LH+GH    +  +    +Q+++G
Sbjct: 22  QKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKG 81

Query: 120 MQVINPMGWDAFGLPAENAA 139
              + P G    G+P +  A
Sbjct: 82  KCCLFPFGLHCTGMPIKACA 101


>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
          Length = 900

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 3/116 (2%)

Query: 86  VLSMFPYPSGKLHMGHVRVYTIS-DTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNL 144
           + S  PY +   H+G++    +S D  AR+ ++R    +   G D +G   E  A+E  L
Sbjct: 268 ITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEGL 327

Query: 145 HPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQ 200
            PQ        H+           S+D    T  P   K TQ +F +L + G   Q
Sbjct: 328 TPQEICDK--YHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQ 381


>gi|239747673 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 714

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 465 PVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNC---SCPRCK 510
           P   P P P    PV +P+ +  +G  GPP+  A  W       CPRC+
Sbjct: 115 PPGSPVPSPSSPRPVPVPSPSCASGWSGPPVGGARAWARLCRRRCPRCR 163


>gi|239741542 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 510

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 465 PVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNC---SCPRCK 510
           P   P P P    PV +P+ +  +G  GPP+  A  W       CPRC+
Sbjct: 115 PPGSPVPSPSSPRPVPVPSPSCASGWSGPPVGGARAWARLCRRRCPRCR 163


>gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 564

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 36/137 (26%), Positives = 57/137 (41%), Gaps = 17/137 (12%)

Query: 625 VHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDA 684
           +HAK KE      EKMSKS  N +  ++ ++ +  D  R + L ++        D     
Sbjct: 309 LHAKGKE------EKMSKSLKNYITIKDFLKTFSPDVFRFFCLRSSYRSAIDYSD----- 357

Query: 685 LPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFT 744
              +L+ QQ L  L +   +ARA  K    QL           LWE  +S    V     
Sbjct: 358 -SAMLQAQQLLLGLGSFLEDARAYMKG---QLACG--SVREAMLWERLSSTKRAVKAALA 411

Query: 745 EDFSLNSAISQLMGLSN 761
           +DF     +  ++GL++
Sbjct: 412 DDFDTPRVVDAILGLAH 428


>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
          Length = 593

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 635 VTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKD 675
           V  +KMSKS  N VDP   + +Y +D  R ++L    P  D
Sbjct: 343 VCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWD 383


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 31.2 bits (69), Expect = 4.5
 Identities = 42/199 (21%), Positives = 68/199 (34%), Gaps = 6/199 (3%)

Query: 325  SSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDT 384
            SS  E+    ++P   CLTP +  N++T       I  KA + G+  SK    S+   D 
Sbjct: 996  SSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK---ESSRISDG 1052

Query: 385  ILAQTLGLAYSEVIETLP-DGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDK 443
               +         + TLP    +  S  A+ T   R+     + Q  +      D  S+ 
Sbjct: 1053 KKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD--SED 1110

Query: 444  LKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVN 503
              D     +     P         GPTP   E L       +S      P  ++ S ++ 
Sbjct: 1111 SSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1170

Query: 504  CSCPRCKGAAKRETDTMDT 522
                     A + T  +D+
Sbjct: 1171 PGLTPANSQASKATPKLDS 1189


>gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]
          Length = 817

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 351 LTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSS 410
           L + E   V L K D+    D+++ +P  +  D     +  ++ S  +E+LP G E   S
Sbjct: 517 LMKSESMPVQLNKGDVVTGSDAQVSVPVQTLTDLQGLSSKNISSSPSVESLPGGREFTGS 576

Query: 411 SAEFTGMTRQDAFLALTQKAR--GKRVGGDVTSDKLK 445
               +  T++D+F +   ++R   K +G   + ++L+
Sbjct: 577 PP--SSATKKDSFFSNISRSRSHSKTMGRKESEEELE 611


>gi|197100773 arginyl-tRNA synthetase 2, mitochondrial precursor
           [Homo sapiens]
          Length = 578

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 6/86 (6%)

Query: 43  ATGKWTKEYTLQTRKDVEKWWHQRIKEQASKI---SEADKSKPKFYVLSMFPYPS--GKL 97
           +TG+ T  + +  R+ + K   Q++ E  SK    SE     P+  ++  F  P+   K 
Sbjct: 82  STGQRTVNFKIN-RELLTKTVLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKF 140

Query: 98  HMGHVRVYTISDTIARFQKMRGMQVI 123
           H+GH+R   I + IA  ++  G QVI
Sbjct: 141 HVGHLRSTIIGNFIANLKEALGHQVI 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,633,024
Number of Sequences: 37866
Number of extensions: 1658300
Number of successful extensions: 3796
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3758
Number of HSP's gapped (non-prelim): 34
length of query: 903
length of database: 18,247,518
effective HSP length: 111
effective length of query: 792
effective length of database: 14,044,392
effective search space: 11123158464
effective search space used: 11123158464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.