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Search of human proteins with 7657683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 987 0.0
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 467 e-131
gi|115648063 solute carrier family 7 (cationic amino acid transp... 449 e-126
gi|115648022 solute carrier family 7 (cationic amino acid transp... 449 e-126
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 443 e-124
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 443 e-124
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 443 e-124
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 421 e-118
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 419 e-117
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 419 e-117
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 403 e-112
gi|33286430 solute carrier family 7 (cationic amino acid transpo... 255 7e-68
gi|71999149 solute carrier family 7, (cationic amino acid transp... 228 1e-59
gi|110347453 solute carrier family 7 (cationic amino acid transp... 103 4e-22
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 99 1e-20
gi|114326550 solute carrier family 7 (cationic amino acid transp... 98 2e-20
gi|114326544 solute carrier family 7 (cationic amino acid transp... 98 2e-20
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 94 2e-19
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 91 2e-18
gi|181337167 solute carrier family 7 (cationic amino acid transp... 81 3e-15
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 37 0.032
gi|134254459 sodium potassium chloride cotransporter 2 [Homo sap... 37 0.055
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ... 33 0.79
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ... 33 0.79
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ... 33 0.79
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 33 0.79
gi|52218842 olfactory receptor, family 10, subfamily R, member 2... 33 0.79
gi|52317261 olfactory receptor, family 5, subfamily M, member 10... 30 3.9
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 30 5.1
gi|52353949 olfactory receptor, family 4, subfamily C, member 46... 29 8.7
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 987 bits (2552), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MVRKPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGA 60
MVRKPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGA
Sbjct: 1 MVRKPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGA 60
Query: 61 GIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGP 120
GIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGP
Sbjct: 61 GIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGP 120
Query: 121 LPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLN 180
LPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLN
Sbjct: 121 LPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLN 180
Query: 181 SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFY 240
SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFY
Sbjct: 181 SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFY 240
Query: 241 YGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLS 300
YGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLS
Sbjct: 241 YGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLS 300
Query: 301 NAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHV 360
NAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHV
Sbjct: 301 NAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHV 360
Query: 361 RKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRP 420
RKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRP
Sbjct: 361 RKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRP 420
Query: 421 FKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIM 480
FKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIM
Sbjct: 421 FKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIM 480
Query: 481 SEKITRTLQIILEVVPEEDKL 501
SEKITRTLQIILEVVPEEDKL
Sbjct: 481 SEKITRTLQIILEVVPEEDKL 501
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 467 bits (1202), Expect = e-131
Identities = 229/476 (48%), Positives = 321/476 (67%), Gaps = 3/476 (0%)
Query: 26 SLGNKEPPGQ-EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWT 84
S P G+ E V L+R +TLL GV+II+GTIIG+GIF++P GVL+ GS G++L +W
Sbjct: 31 SADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWA 90
Query: 85 VCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISL 144
CGV S+ GAL YAELGTTI KSGG Y Y+LEV+G LPAF+++W+ELLIIRP++ +++L
Sbjct: 91 ACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVAL 150
Query: 145 AFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILI 204
F Y+L+P F C +PE A KL+ + + ++ +N SV + R+Q KL A+ +
Sbjct: 151 VFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALAL 210
Query: 205 IIVPGVMQLIKGQTQNFKDAFS--GRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENP 262
II+ G +Q+ KG N FS G + + LA Y G++AY GW YLNFVTEE+ NP
Sbjct: 211 IILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINP 270
Query: 263 EKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIF 322
+ +PLAI IS+ IVT+ YVLTN+AYFTT++ E++L S AVAV F LG S +P+F
Sbjct: 271 YRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVF 330
Query: 323 VALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFS 382
V LSCFGS+NG +F SRLF+V SREGHLP ILSMIH + TP+P+++ +T++ FS
Sbjct: 331 VGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFS 390
Query: 383 GDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALS 442
D+ S++NF SF WL + LA+ G+I+LR++ P++ RP KV L +P F CLF++A+S
Sbjct: 391 KDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVS 450
Query: 443 LYSDPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEE 498
+ P GIGF I L+G+P Y+ + W KP+W T Q +++VVP+E
Sbjct: 451 FWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQE 506
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 449 bits (1154), Expect = e-126
Identities = 220/473 (46%), Positives = 325/473 (68%), Gaps = 5/473 (1%)
Query: 32 PP--GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVL 89
PP E +QLK++++LL GVS+++G +IG+GIF+SPKGVL +T S GMSL +W + G+
Sbjct: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
Query: 90 SLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRY 149
S+ GAL YAELGTTI KSG Y YILE FG AF+R+WV LL++ P A+I++ F Y
Sbjct: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
Query: 150 ILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPG 209
I++P F C+ P LA +L+ A I ++ +N V W R+Q T+ K+ A++ IIV G
Sbjct: 151 IIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMG 210
Query: 210 VMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLA 269
+++L +G +++F+DAF G + L LA Y +++Y+GW LNFVTEE++NPE+ +PLA
Sbjct: 211 LVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 270
Query: 270 ICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFG 329
I ISM IVT+ Y+LTNVAY+T +N ++L S+AVAVTF+++ G FS +PI VALSCFG
Sbjct: 271 IGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFG 330
Query: 330 SMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLL 389
+N +FA SRLF+V SREGHLP++LSMIH+ + TP+PA++ + +I L D+ L+
Sbjct: 331 GLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLI 390
Query: 390 NFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFS 449
N+ SF+ W F+GL+V G +YLR+K P RP K+ +F P +F +F+V + L++D +
Sbjct: 391 NYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTIN 450
Query: 450 TGIGFVITLTGVPAYYL--FIIWDKKPRWFRIMSEKITR-TLQIILEVVPEED 499
+ IG I L+GVP Y++ ++ ++P + R + ITR T Q+ V+ E D
Sbjct: 451 SLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 449 bits (1154), Expect = e-126
Identities = 220/473 (46%), Positives = 325/473 (68%), Gaps = 5/473 (1%)
Query: 32 PP--GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVL 89
PP E +QLK++++LL GVS+++G +IG+GIF+SPKGVL +T S GMSL +W + G+
Sbjct: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
Query: 90 SLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRY 149
S+ GAL YAELGTTI KSG Y YILE FG AF+R+WV LL++ P A+I++ F Y
Sbjct: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
Query: 150 ILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPG 209
I++P F C+ P LA +L+ A I ++ +N V W R+Q T+ K+ A++ IIV G
Sbjct: 151 IIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMG 210
Query: 210 VMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLA 269
+++L +G +++F+DAF G + L LA Y +++Y+GW LNFVTEE++NPE+ +PLA
Sbjct: 211 LVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 270
Query: 270 ICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFG 329
I ISM IVT+ Y+LTNVAY+T +N ++L S+AVAVTF+++ G FS +PI VALSCFG
Sbjct: 271 IGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFG 330
Query: 330 SMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLL 389
+N +FA SRLF+V SREGHLP++LSMIH+ + TP+PA++ + +I L D+ L+
Sbjct: 331 GLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLI 390
Query: 390 NFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFS 449
N+ SF+ W F+GL+V G +YLR+K P RP K+ +F P +F +F+V + L++D +
Sbjct: 391 NYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTIN 450
Query: 450 TGIGFVITLTGVPAYYL--FIIWDKKPRWFRIMSEKITR-TLQIILEVVPEED 499
+ IG I L+GVP Y++ ++ ++P + R + ITR T Q+ V+ E D
Sbjct: 451 SLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 443 bits (1139), Expect = e-124
Identities = 214/474 (45%), Positives = 323/474 (68%), Gaps = 2/474 (0%)
Query: 27 LGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVC 86
LG+ PG E+V+LK++++LL GV +I+G +IG+GIF+SPKGVL + S G+SL IW V
Sbjct: 20 LGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVG 79
Query: 87 GVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 146
G+ S+FGAL YAELGTTIKKSG Y YILE FG AF+R+W LLII P + A+I++ F
Sbjct: 80 GLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITF 139
Query: 147 GRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIII 206
Y+++P F C P A +L+ A I ++ +N V W +Q T+ K+ A++ +I
Sbjct: 140 ANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVI 199
Query: 207 VPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTI 266
V G+++L +G + +F+++F G ++ + LA Y +++Y+GW LN+VTEE++NPE+ +
Sbjct: 200 VAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNL 259
Query: 267 PLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALS 326
PL+I ISM IVTI Y+LTNVAY+T ++ ++L S+AVAVTF++++ G F+ +P+ VALS
Sbjct: 260 PLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALS 319
Query: 327 CFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 386
CFG +N + A SRLF+V SREGHLP+ + MIHV + TP+P+++ + +I L D+
Sbjct: 320 CFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIF 379
Query: 387 SLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSD 446
L+N+ SF+ W F+GL++ G +YLR+K PD RP K+ +F P +F +F+VA+ LYSD
Sbjct: 380 QLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSD 439
Query: 447 PFSTGIGFVITLTGVPAYYLFI--IWDKKPRWFRIMSEKITRTLQIILEVVPEE 498
++ IG I L+G+P Y+L I K+P + R + TR LQ++ V E
Sbjct: 440 TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAE 493
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 443 bits (1139), Expect = e-124
Identities = 214/474 (45%), Positives = 323/474 (68%), Gaps = 2/474 (0%)
Query: 27 LGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVC 86
LG+ PG E+V+LK++++LL GV +I+G +IG+GIF+SPKGVL + S G+SL IW V
Sbjct: 20 LGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVG 79
Query: 87 GVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 146
G+ S+FGAL YAELGTTIKKSG Y YILE FG AF+R+W LLII P + A+I++ F
Sbjct: 80 GLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITF 139
Query: 147 GRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIII 206
Y+++P F C P A +L+ A I ++ +N V W +Q T+ K+ A++ +I
Sbjct: 140 ANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVI 199
Query: 207 VPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTI 266
V G+++L +G + +F+++F G ++ + LA Y +++Y+GW LN+VTEE++NPE+ +
Sbjct: 200 VAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNL 259
Query: 267 PLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALS 326
PL+I ISM IVTI Y+LTNVAY+T ++ ++L S+AVAVTF++++ G F+ +P+ VALS
Sbjct: 260 PLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALS 319
Query: 327 CFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 386
CFG +N + A SRLF+V SREGHLP+ + MIHV + TP+P+++ + +I L D+
Sbjct: 320 CFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIF 379
Query: 387 SLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSD 446
L+N+ SF+ W F+GL++ G +YLR+K PD RP K+ +F P +F +F+VA+ LYSD
Sbjct: 380 QLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSD 439
Query: 447 PFSTGIGFVITLTGVPAYYLFI--IWDKKPRWFRIMSEKITRTLQIILEVVPEE 498
++ IG I L+G+P Y+L I K+P + R + TR LQ++ V E
Sbjct: 440 TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAE 493
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 443 bits (1139), Expect = e-124
Identities = 214/474 (45%), Positives = 323/474 (68%), Gaps = 2/474 (0%)
Query: 27 LGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVC 86
LG+ PG E+V+LK++++LL GV +I+G +IG+GIF+SPKGVL + S G+SL IW V
Sbjct: 20 LGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVG 79
Query: 87 GVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF 146
G+ S+FGAL YAELGTTIKKSG Y YILE FG AF+R+W LLII P + A+I++ F
Sbjct: 80 GLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITF 139
Query: 147 GRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIII 206
Y+++P F C P A +L+ A I ++ +N V W +Q T+ K+ A++ +I
Sbjct: 140 ANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVI 199
Query: 207 VPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTI 266
V G+++L +G + +F+++F G ++ + LA Y +++Y+GW LN+VTEE++NPE+ +
Sbjct: 200 VAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNL 259
Query: 267 PLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALS 326
PL+I ISM IVTI Y+LTNVAY+T ++ ++L S+AVAVTF++++ G F+ +P+ VALS
Sbjct: 260 PLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALS 319
Query: 327 CFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLD 386
CFG +N + A SRLF+V SREGHLP+ + MIHV + TP+P+++ + +I L D+
Sbjct: 320 CFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIF 379
Query: 387 SLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSD 446
L+N+ SF+ W F+GL++ G +YLR+K PD RP K+ +F P +F +F+VA+ LYSD
Sbjct: 380 QLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSD 439
Query: 447 PFSTGIGFVITLTGVPAYYLFI--IWDKKPRWFRIMSEKITRTLQIILEVVPEE 498
++ IG I L+G+P Y+L I K+P + R + TR LQ++ V E
Sbjct: 440 TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAE 493
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 421 bits (1082), Expect = e-118
Identities = 213/467 (45%), Positives = 311/467 (66%), Gaps = 4/467 (0%)
Query: 38 VQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSY 97
V LK+++ L+ II+G IIG+GIF+SPKGVL+N GSVG++L +W V G +++ GAL Y
Sbjct: 34 VALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCY 93
Query: 98 AELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQ 157
AELG TI KSGG Y+Y+ ++FG L F+R+W+ +L+I P AVI+L F Y+L+P F
Sbjct: 94 AELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPT 153
Query: 158 CEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQ 217
C PE ++L+ A+ + ++ +N SV W+ R+Q T KL A+ +II+ G++Q+ KG+
Sbjct: 154 CFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGE 213
Query: 218 T--QNFKDAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISM 274
K+AF ++ I + LAF G +AY GW +LN+VTEE+ +P K +P AI IS+
Sbjct: 214 YFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISI 273
Query: 275 AIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGG 334
+VT YV NVAY T ++ +ELL SNAVAVTF E+LLG + +PI VALS FG +NG
Sbjct: 274 PLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGS 333
Query: 335 VFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSF 394
+F SRLF+ +REGHLP +L+MIHV++ TP+PA++ T++ML + D+ +L+N++ F
Sbjct: 334 LFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGF 393
Query: 395 ARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGF 454
+LF G+ VAG I LR+K PD+ RP K+ L P ++ F++ SL+S+P GIG
Sbjct: 394 INYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGL 453
Query: 455 VITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVV-PEEDK 500
I LTGVP Y+L + W KP+ F E +T Q + VV PE ++
Sbjct: 454 AIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVER 500
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 419 bits (1076), Expect = e-117
Identities = 210/475 (44%), Positives = 312/475 (65%), Gaps = 6/475 (1%)
Query: 26 SLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTV 85
S+ ++EP + L++++ L+ G+SII+GTIIG+GIF+SPK VL NT +VG L IW
Sbjct: 15 SIQSQEP---KTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAA 71
Query: 86 CGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLA 145
CGVL+ GAL +AELGT I KSGG Y Y++E +GP+PA++ W L++I+P + A+I L+
Sbjct: 72 CGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLS 131
Query: 146 FGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILII 205
F Y+ PF++ C+ P++ +K + A I + +NS+SV + +Q T KL + II
Sbjct: 132 FSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAII 191
Query: 206 IVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
I+ G++ L +G T+NF ++F G S+ + LAFY G++AY GW LN++TEE+ NP +
Sbjct: 192 IISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRN 251
Query: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325
+PLAI I + +VT Y+L NV+YFT + A ELL S AVAVTF +R+L S VP+FVA
Sbjct: 252 LPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAF 311
Query: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385
S G+ NG F RL YVA REGH+ ++LS I VR+ TP PA+I + I + GD+
Sbjct: 312 STIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDI 371
Query: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445
+SL+N+ SFA WLF GL + GLI +R+ ++ RP KVP+ IP L + +F+V + S
Sbjct: 372 NSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIIS 431
Query: 446 DPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499
P + V+ L+G+ Y+LF+ + K W + +S+ IT LQ+++EVVP E+
Sbjct: 432 KPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEE 484
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 419 bits (1076), Expect = e-117
Identities = 210/475 (44%), Positives = 312/475 (65%), Gaps = 6/475 (1%)
Query: 26 SLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTV 85
S+ ++EP + L++++ L+ G+SII+GTIIG+GIF+SPK VL NT +VG L IW
Sbjct: 15 SIQSQEP---KTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAA 71
Query: 86 CGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLA 145
CGVL+ GAL +AELGT I KSGG Y Y++E +GP+PA++ W L++I+P + A+I L+
Sbjct: 72 CGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLS 131
Query: 146 FGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILII 205
F Y+ PF++ C+ P++ +K + A I + +NS+SV + +Q T KL + II
Sbjct: 132 FSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAII 191
Query: 206 IVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
I+ G++ L +G T+NF ++F G S+ + LAFY G++AY GW LN++TEE+ NP +
Sbjct: 192 IISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRN 251
Query: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325
+PLAI I + +VT Y+L NV+YFT + A ELL S AVAVTF +R+L S VP+FVA
Sbjct: 252 LPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAF 311
Query: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385
S G+ NG F RL YVA REGH+ ++LS I VR+ TP PA+I + I + GD+
Sbjct: 312 STIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDI 371
Query: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445
+SL+N+ SFA WLF GL + GLI +R+ ++ RP KVP+ IP L + +F+V + S
Sbjct: 372 NSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIIS 431
Query: 446 DPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499
P + V+ L+G+ Y+LF+ + K W + +S+ IT LQ+++EVVP E+
Sbjct: 432 KPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQKISKPITMHLQMLMEVVPPEE 484
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 403 bits (1036), Expect = e-112
Identities = 206/471 (43%), Positives = 307/471 (65%), Gaps = 3/471 (0%)
Query: 32 PPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSL 91
P E+V LK+++ LL +IIIG IIG+GIFISPKGVL+++GSVG++L +W + G ++
Sbjct: 28 PGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTA 87
Query: 92 FGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYIL 151
G+L YAELG I KSGG Y Y+ E+FG L F+ +W +LI+ P + AVIS+ F Y+L
Sbjct: 88 LGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVL 147
Query: 152 EPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVM 211
+P F C P A ++++ + ++ +NS SV W+ RIQ T KL A+ +II G++
Sbjct: 148 QPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLL 207
Query: 212 QLIKGQTQNFK--DAFS-GRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPL 268
Q+ +G + + +AF+ S+ L LAF G +A++GW +LN+VTEE+ + K +P
Sbjct: 208 QIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPR 267
Query: 269 AICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCF 328
AI IS+ +VT Y TN+AYFT ++ +ELL SNAVAVTF E+LLG FS +P+ VALS F
Sbjct: 268 AIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTF 327
Query: 329 GSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSL 388
G +NG +F SRL + +REGHLP +L+MIHVR TP+PA++V T +++ GD +L
Sbjct: 328 GGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTL 387
Query: 389 LNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPF 448
+N++SF +L G+ + GL+ LR++ P +HRP KV L IP + F++ S S+P
Sbjct: 388 INYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPM 447
Query: 449 STGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVVPEED 499
G+G +I LTGVP ++L + W KP+ ++E +T Q + VV +D
Sbjct: 448 VCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 498
>gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo
sapiens]
Length = 332
Score = 255 bits (651), Expect = 7e-68
Identities = 134/296 (45%), Positives = 193/296 (65%), Gaps = 4/296 (1%)
Query: 209 GVMQLIKGQT--QNFKDAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
G++Q+ KG+ K+AF ++ I + LAF G +AY GW +LN+VTEE+ +P K
Sbjct: 2 GIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKN 61
Query: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325
+P AI IS+ +VT YV NVAY T ++ +ELL SNAVAVTF E+LLG + +PI VAL
Sbjct: 62 LPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 121
Query: 326 SCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDL 385
S FG +NG +F SRLF+ +REGHLP +L+MIHV++ TP+PA++ T++ML + D+
Sbjct: 122 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDM 181
Query: 386 DSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYS 445
+L+N++ F +LF G+ VAG I LR+K PD+ RP K+ L P ++ F++ SL+S
Sbjct: 182 YTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWS 241
Query: 446 DPFSTGIGFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEVV-PEEDK 500
+P GIG I LTGVP Y+L + W KP+ F E +T Q + VV PE ++
Sbjct: 242 EPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVER 297
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 228 bits (581), Expect = 1e-59
Identities = 142/464 (30%), Positives = 246/464 (53%), Gaps = 11/464 (2%)
Query: 36 EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQ-NTGSVGMSLTIWTVCGVLSLFGA 94
EK+QLKR G S ++ IIGAGIF+SPKGVL + +VG+SL +W C +L++
Sbjct: 5 EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64
Query: 95 LSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPF 154
L AE+ + SG Y ++ FG AF+ +W L + A +L Y ++PF
Sbjct: 65 LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL-GSGVVAGQALLLAEYSIQPF 123
Query: 155 FIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLI 214
F C +P+L K + + +V +L S V +QI + K++ + I + GV+ LI
Sbjct: 124 FPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLI 183
Query: 215 KGQTQN---FKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAIC 271
+G+ +N F++AF I+ L A + G +AY+G + E++ P TIP I
Sbjct: 184 RGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIF 243
Query: 272 ISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSM 331
++ +VT+ Y+L N++Y T + E+L S+AVA+T+++R + + +P ++ S F ++
Sbjct: 244 TALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNL 303
Query: 332 NGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNF 391
+F SR Y+AS+EG LP + + ++ +P AV++L L + + L L+N+
Sbjct: 304 LISIFKSSRPIYLASQEGQLPLLFNTLNSHS-SPFTAVLLLVTLGSLAIILTSLIDLINY 362
Query: 392 LSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFSTG 451
+ F L+ L + G++ RY+ P++ P+KV L P + +V + L P
Sbjct: 363 IFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHY 422
Query: 452 I-GFVITLTGVPAYYLFIIWDKKPRWFRIMSEKITRTLQIILEV 494
+ ++ L+G+ Y I + + WF EK+T LQ++ +
Sbjct: 423 VYVLLLVLSGLLFYIPLIHFKIRLAWF----EKMTCYLQLLFNI 462
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 103 bits (257), Expect = 4e-22
Identities = 99/396 (25%), Positives = 178/396 (44%), Gaps = 29/396 (7%)
Query: 37 KVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALS 96
+ L+R ++ L + +G ++G+G+++ V + + L+ + V V SL AL
Sbjct: 30 ETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLS-FGVAAVASLLAALC 88
Query: 97 YAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATAVISLAFGRYILEPF 154
YAE G + ++G Y + G L AF+ W LL II AA A A+ Y+ F
Sbjct: 89 YAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVA---RAWSGYLDSMF 145
Query: 155 ------FIQCEIPELAIKLI------TAVGITVVMVLNSMSVSWSARIQIFL--TFCKLT 200
F + + + L+ A GI ++L S VS AR+ +L TF ++
Sbjct: 146 SHSIRNFTETHVGSWQVPLLGHYPDFLAAGI---ILLASAFVSCGARVSSWLNHTFSAIS 202
Query: 201 AILIIIVPGVMQLIKGQTQNFKDAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEV 259
++I+ + ++ I Q N+ G + + YA+ G+ + +EE
Sbjct: 203 LLVILFIV-ILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEA 261
Query: 260 ENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSER--LLGNFSL 317
+NP +++PLAI IS+AI Y+L + + L +A+A F +R F +
Sbjct: 262 QNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIV 321
Query: 318 AVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTM 377
A A++ + +F++ R+ Y + +G ++ + +H R P+ + LT
Sbjct: 322 AAGSICAMNTV--LLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTA 379
Query: 378 IMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYK 413
+ DL+SL+ FLS L +I LR++
Sbjct: 380 FLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ 415
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 98.6 bits (244), Expect = 1e-20
Identities = 97/419 (23%), Positives = 180/419 (42%), Gaps = 48/419 (11%)
Query: 35 QEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGA 94
+E+ +L R + V++ +G+ +GAG+++ V + + ++ + + + S+
Sbjct: 23 REETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVIS-FLIAALASVLAG 81
Query: 95 LSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATA-VISLAFGRYIL 151
L Y E G + K+G Y Y G L AF+ W +L II ++ A S F I
Sbjct: 82 LCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIG 141
Query: 152 EPF------FIQCEIPELAIKLITAVGITVVMVLN---SMSVSWSARIQIFLTFCKLTAI 202
P + P + + + ++++L ++ V SA + T + +
Sbjct: 142 RPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVL 201
Query: 203 LIIIVPGVMQLIKGQTQNFK-----------------DAFSGRDSSITRLPLAFYYGM-- 243
I+V G +KG +N++ D G+ +P F +
Sbjct: 202 GFIMVSG---FVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSG 258
Query: 244 -----YAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELL 298
YA+ G+ + EEV+NP+K IP+ I S+ I I Y V+ T+
Sbjct: 259 AATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYF--GVSAALTLMMPYFC 316
Query: 299 LSNAVAVTFSERLLG----NFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEI 354
L N + + + +G +++AV ALS S+ G +F + R+ Y + +G L +
Sbjct: 317 LDNNSPLPDAFKHVGWEGAKYAVAVGSLCALS--ASLLGSMFPMPRVIYAMAEDGLLFKF 374
Query: 355 LSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYK 413
L+ ++ R TP+ A + + +M F DL L++ +S L L A ++ LRY+
Sbjct: 375 LANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQ 433
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 98.2 bits (243), Expect = 2e-20
Identities = 98/421 (23%), Positives = 182/421 (43%), Gaps = 47/421 (11%)
Query: 34 GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTI-WTVCGVLSLF 92
G + +L R ++ L V++ +G+ +GAG+++ V ++ G S+ I + V + S+
Sbjct: 22 GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKD--KAGPSIVICFLVAALSSVL 79
Query: 93 GALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF------ 146
L YAE G + +SG Y Y G L AF W L++ TA ++ A+
Sbjct: 80 AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDN 138
Query: 147 --GRYILEPF--FIQCEIPELAIKLITAVGITVVMVLN---SMSVSWSARIQIFLTFCKL 199
G +I + I +P + + + +V++L ++ S SA + T L
Sbjct: 139 LIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNL 198
Query: 200 TAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYG----------------- 242
+ +++ G +KG N+K + ++ L + G
Sbjct: 199 LVLGFVMISG---FVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILR 255
Query: 243 -----MYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEEL 297
YA+ G+ + EE +NP+++IP+ I IS+++ + Y + A + +L
Sbjct: 256 GAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQL 315
Query: 298 LLSNAV--AVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEIL 355
+ + A + + +AV ALS S+ G +F + R+ Y + +G L +L
Sbjct: 316 QPESPLPEAFLYIGWAPARYVVAVGSLCALST--SLLGSMFPMPRVIYAMAEDGLLFRVL 373
Query: 356 SMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCP 415
+ IH TP+ A +V + M F L L++ +S L L ++ LRY+ P
Sbjct: 374 ARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ-P 432
Query: 416 D 416
D
Sbjct: 433 D 433
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 98.2 bits (243), Expect = 2e-20
Identities = 98/421 (23%), Positives = 182/421 (43%), Gaps = 47/421 (11%)
Query: 34 GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTI-WTVCGVLSLF 92
G + +L R ++ L V++ +G+ +GAG+++ V ++ G S+ I + V + S+
Sbjct: 22 GMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKD--KAGPSIVICFLVAALSSVL 79
Query: 93 GALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAF------ 146
L YAE G + +SG Y Y G L AF W L++ TA ++ A+
Sbjct: 80 AGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDN 138
Query: 147 --GRYILEPF--FIQCEIPELAIKLITAVGITVVMVLN---SMSVSWSARIQIFLTFCKL 199
G +I + I +P + + + +V++L ++ S SA + T L
Sbjct: 139 LIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNL 198
Query: 200 TAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYG----------------- 242
+ +++ G +KG N+K + ++ L + G
Sbjct: 199 LVLGFVMISG---FVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILR 255
Query: 243 -----MYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEEL 297
YA+ G+ + EE +NP+++IP+ I IS+++ + Y + A + +L
Sbjct: 256 GAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQL 315
Query: 298 LLSNAV--AVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEIL 355
+ + A + + +AV ALS S+ G +F + R+ Y + +G L +L
Sbjct: 316 QPESPLPEAFLYIGWAPARYVVAVGSLCALST--SLLGSMFPMPRVIYAMAEDGLLFRVL 373
Query: 356 SMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCP 415
+ IH TP+ A +V + M F L L++ +S L L ++ LRY+ P
Sbjct: 374 ARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ-P 432
Query: 416 D 416
D
Sbjct: 433 D 433
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 94.4 bits (233), Expect = 2e-19
Identities = 100/423 (23%), Positives = 184/423 (43%), Gaps = 58/423 (13%)
Query: 36 EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTI-WTVCGVLSLFGA 94
E +L R ++ + +++ +G+ +GAG+++ V + G S+ + + + + S+
Sbjct: 26 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAK--ADSGPSIVVSFLIAALASVMAG 83
Query: 95 LSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATA---------VIS 143
L YAE G + K+G Y Y G L AF+ W +L +I ++ A ++S
Sbjct: 84 LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 143
Query: 144 LAFGRYILEPFFIQ----CEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKL 199
G+++ F + E P+ + I ++ L S V SA + T +
Sbjct: 144 KQIGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNI 199
Query: 200 TAILIIIVPGVMQLIKGQTQNFK--DAFSGRDSSITRLP-----LAFY-------YG--- 242
+L ++V G +KG N+K + F S+ R P + Y YG
Sbjct: 200 LVLLFVMVAG---FVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTG 256
Query: 243 --------MYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINA 294
YA+ G+ + EEV NP+K IP+ I S+ + + Y V+ T+
Sbjct: 257 TLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYF--GVSAALTLMM 314
Query: 295 EELLLSNAVAVTFSERLLG----NFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGH 350
LL + + +G + +A ALS S+ G +F + R+ Y + +G
Sbjct: 315 PYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALST--SLLGSIFPMPRVIYAMAEDGL 372
Query: 351 LPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYL 410
L + L+ I+ + TP+ A + + +M F DL +L++ +S + L A ++ L
Sbjct: 373 LFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 432
Query: 411 RYK 413
RY+
Sbjct: 433 RYQ 435
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 90.9 bits (224), Expect = 2e-18
Identities = 98/423 (23%), Positives = 185/423 (43%), Gaps = 59/423 (13%)
Query: 36 EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTI-WTVCGVLSLFGA 94
E +L R ++ + +++ +G+ +GAG+++ V + G S+ + + + + S+
Sbjct: 66 EDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAK--ADSGPSIVVSFLIAALASVMAG 123
Query: 95 LSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELL--IIRPAATA---------VIS 143
L YAE G + K+G Y Y G L AF+ W +L +I ++ A ++S
Sbjct: 124 LCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLS 183
Query: 144 LAFGRYILEPFFIQ----CEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKL 199
G+++ F + E P+ + I ++ L S V SA + T +
Sbjct: 184 KQIGQFLRTYFRMNYTGLAEYPDFFAVCL----ILLLAGLLSFGVKESAWVNKVFTAVNI 239
Query: 200 TAILIIIVPGVMQLIKGQTQNFK--DAFSGRDSSITRLP-----LAFY-------YG--- 242
+L ++V G +KG N+K + F S+ R P + Y YG
Sbjct: 240 LVLLFVMVAG---FVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTG 296
Query: 243 --------MYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINA 294
YA+ G+ + EEV NP+K IP+ I S+ + + Y V+ T+
Sbjct: 297 TLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYF--GVSAALTLMM 354
Query: 295 EELLLSNAVAVTFSERLLG----NFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGH 350
LL + + +G + +A ALS S+ G +F + R+ + +R+G
Sbjct: 355 PYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALST--SLLGSMFPLPRILFAMARDGL 412
Query: 351 LPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYL 410
L L+ + ++ +P+ A + ++ +M F DL +L++ +S + L A ++ L
Sbjct: 413 LFRFLARVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 471
Query: 411 RYK 413
RY+
Sbjct: 472 RYQ 474
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 80.9 bits (198), Expect = 3e-15
Identities = 101/422 (23%), Positives = 173/422 (40%), Gaps = 49/422 (11%)
Query: 20 VNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMS 79
V L G G + Q+ V L +S+ +G+ +G G+++ V + G+
Sbjct: 32 VESMLEGTGTTTAHGTKLAQVLTTVDL---ISLGVGSCVGTGMYVVSGLVAKEMAGPGVI 88
Query: 80 LTIWTVCGVLSLFGALSYAELGTTIKKS-GGHYTYILEVFGPLPAFVRVW---VELLIIR 135
++ + + V S+ + YAE G + K+ G YTY G AF W +E LI
Sbjct: 89 VS-FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGT 147
Query: 136 PAATAVISLAF--------GRYILEPFFI-------QCEIPELAIKLITAVGITVVMVLN 180
A + +S F R++ + + P+L + L+ AV +T+++ L
Sbjct: 148 AAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDL-LALLIAVIVTIIVALG 206
Query: 181 SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKG----QTQNFKDAFSGRDSSITRLP 236
V S L L + I++ G+ I G + Q +SG
Sbjct: 207 ---VKNSIGFNNVLNVLNLAVWVFIMIAGLF-FINGKYWAEGQFLPHGWSGVLQGAATC- 261
Query: 237 LAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAI-----VTIGYVLTNVAYFTT 291
YA+ G+ + EE +NP +IP AI S+ I V++ +LT + + T
Sbjct: 262 ------FYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYT 315
Query: 292 INAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHL 351
I+ E L+ VA F F +A+ L+ S+ G +F + R+ Y + +G L
Sbjct: 316 IDTESPLMEMFVAHGF---YAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLL 370
Query: 352 PEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLR 411
L+ + TP+ A IV L ++ L L+ +S L L ++ LR
Sbjct: 371 FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLR 430
Query: 412 YK 413
Y+
Sbjct: 431 YQ 432
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 37.4 bits (85), Expect = 0.032
Identities = 74/359 (20%), Positives = 134/359 (37%), Gaps = 55/359 (15%)
Query: 57 IIGAGIFISPKGVLQNTGSV-GMSLTIWTVC----GVLSLFGALSYAELGTTIKKSGGHY 111
I G +F+ ++ NTG + GM L + + VLS G + +G SGG Y
Sbjct: 53 IFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIG-----SGGVY 107
Query: 112 TYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQC---EIPEL----- 163
+ I V G + T + FG+ + +I I +L
Sbjct: 108 SMISSVLGG--------------QTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGN 153
Query: 164 --AIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQ---- 217
A++ I+ + ++ +N V W R+Q+ L F + L +V L
Sbjct: 154 IWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIG 213
Query: 218 ------TQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAIC 271
N +S +S T + F AG+ + ++ P +IPL
Sbjct: 214 YSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGF----NMGGDLREPAASIPLGSL 269
Query: 272 ISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSM 331
++ I Y++ E L +A S L+G L + + +S S
Sbjct: 270 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVS--LMGFLFL---LGLYISSLASC 324
Query: 332 NGGVFAVSRLFYVASREGHLPEILSMIHVR--KHTPLPAVIVLHPLTMIMLFSGDLDSL 388
GG++ R+ ++E +P + + + TP+ A+ + +TM +F G ++ L
Sbjct: 325 MGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVL 383
>gi|134254459 sodium potassium chloride cotransporter 2 [Homo
sapiens]
Length = 1099
Score = 36.6 bits (83), Expect = 0.055
Identities = 54/276 (19%), Positives = 106/276 (38%), Gaps = 33/276 (11%)
Query: 33 PGQEKVQLKR-------KVTLLRGVSI-IIGTIIGAGIFISPKGVLQNTGSVGMSLTIWT 84
PG E+ + K K ++GV + + I G +FI ++ G +G+ + I
Sbjct: 159 PGDEQAENKEDDQAGVVKFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAG-IGLGVLIIL 217
Query: 85 VCGVLSLFGALSYAELGTT-IKKSGGHYTYILEVFGP--------LPAFVRVWVELLIIR 135
+ +++ LS + + T + GG Y I GP + AF + +
Sbjct: 218 LSTMVTSITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVV 277
Query: 136 PAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLT 195
A V+ L L+ P I++I ++ + +++ ++ + W A+ Q+ L
Sbjct: 278 GFAETVVDL------LKESDSMMVDPTNDIRIIGSITVVILLGISVAGMEWEAKAQVILL 331
Query: 196 FCKLTAILIIIVPGVMQ---------LIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAY 246
L AI + V+ Q F + F R + F A
Sbjct: 332 VILLIAIANFFIGTVIPSNNEKKSRGFFNYQASIFAENFGPRFTKGEGFFSVFAIFFPAA 391
Query: 247 AGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYV 282
G ++ ++E+P+ IP +++ I T+ Y+
Sbjct: 392 TGILAGANISGDLEDPQDAIPRGTMLAIFITTVAYL 427
>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
sapiens]
Length = 1021
Score = 32.7 bits (73), Expect = 0.79
Identities = 44/219 (20%), Positives = 89/219 (40%), Gaps = 22/219 (10%)
Query: 78 MSLTIWTVCGVLSLFGALSYAELGTTIK-KSGGHYTYILEVFGPLPAFVRVWVELLIIRP 136
+S+T+ ++ G LS + + T K KSGG Y I GP + +
Sbjct: 177 LSVTVTSITG-------LSISAISTNGKVKSGGTYFLISRSLGP-ELGGSIGLIFAFANA 228
Query: 137 AATAVISLAFG---RYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIF 193
A+ ++ F R +L+ + P I++I V +TV++ ++ + W ++ Q+
Sbjct: 229 VGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKAQVL 288
Query: 194 LTFCKLTA-----ILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAY-- 246
+ + + +I P + KG D F R P ++GM++
Sbjct: 289 FFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFF 348
Query: 247 ---AGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYV 282
G ++ ++++P IP +++ TI Y+
Sbjct: 349 PSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYL 387
>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
sapiens]
Length = 1029
Score = 32.7 bits (73), Expect = 0.79
Identities = 44/219 (20%), Positives = 89/219 (40%), Gaps = 22/219 (10%)
Query: 78 MSLTIWTVCGVLSLFGALSYAELGTTIK-KSGGHYTYILEVFGPLPAFVRVWVELLIIRP 136
+S+T+ ++ G LS + + T K KSGG Y I GP + +
Sbjct: 176 LSVTVTSITG-------LSISAISTNGKVKSGGTYFLISRSLGP-ELGGSIGLIFAFANA 227
Query: 137 AATAVISLAFG---RYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIF 193
A+ ++ F R +L+ + P I++I V +TV++ ++ + W ++ Q+
Sbjct: 228 VGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKAQVL 287
Query: 194 LTFCKLTA-----ILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAY-- 246
+ + + +I P + KG D F R P ++GM++
Sbjct: 288 FFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFF 347
Query: 247 ---AGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYV 282
G ++ ++++P IP +++ TI Y+
Sbjct: 348 PSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYL 386
>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
sapiens]
Length = 1030
Score = 32.7 bits (73), Expect = 0.79
Identities = 44/219 (20%), Positives = 89/219 (40%), Gaps = 22/219 (10%)
Query: 78 MSLTIWTVCGVLSLFGALSYAELGTTIK-KSGGHYTYILEVFGPLPAFVRVWVELLIIRP 136
+S+T+ ++ G LS + + T K KSGG Y I GP + +
Sbjct: 177 LSVTVTSITG-------LSISAISTNGKVKSGGTYFLISRSLGP-ELGGSIGLIFAFANA 228
Query: 137 AATAVISLAFG---RYILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIF 193
A+ ++ F R +L+ + P I++I V +TV++ ++ + W ++ Q+
Sbjct: 229 VGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKAQVL 288
Query: 194 LTFCKLTA-----ILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAY-- 246
+ + + +I P + KG D F R P ++GM++
Sbjct: 289 FFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFF 348
Query: 247 ---AGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYV 282
G ++ ++++P IP +++ TI Y+
Sbjct: 349 PSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYL 387
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 32.7 bits (73), Expect = 0.79
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 18/191 (9%)
Query: 258 EVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSL 317
E+++P + IPL +++A YVL + + ++ + LL R + +
Sbjct: 290 ELKDPSRAIPLGTIVAVAYTFFVYVL--LFFLSSFTCDRTLLQEDYGFF---RAISLWPP 344
Query: 318 AVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHV--RKHTPLPAVIVLHPL 375
V I + + + + SR+ + +R+ IL+ V R P AV+ L
Sbjct: 345 LVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGL 404
Query: 376 TMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIP--ALFSF 433
++L +G L++L ++ + + A L L + P F P +LFS+
Sbjct: 405 VQLVLLAGKLNTLAAVVTV--FYLVAYAAVDLSCLSLEWA------SAPNFRPTFSLFSW 456
Query: 434 -TCLFMVALSL 443
TCL VA L
Sbjct: 457 HTCLLGVASCL 467
>gi|52218842 olfactory receptor, family 10, subfamily R, member 2
[Homo sapiens]
Length = 335
Score = 32.7 bits (73), Expect = 0.79
Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 15/127 (11%)
Query: 321 IFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRK--HTPLPAVI-------- 370
+ + S G + +F V Y+ G++ I+S+IH+ K HTP+ +
Sbjct: 33 LLLGFSSLGEIQLALFVVFLFLYLVILSGNVT-IISVIHLDKSLHTPMYFFLGILSTSET 91
Query: 371 ----VLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLF 426
V+ P +I L S N + + F+G A+ + L D + PL
Sbjct: 92 FYTFVILPKMLINLLSVARTISFNCCALQMFFFLGFAITNCLLLGVMGYDRYAAICHPLH 151
Query: 427 IPALFSF 433
P L S+
Sbjct: 152 YPTLMSW 158
>gi|52317261 olfactory receptor, family 5, subfamily M, member 10
[Homo sapiens]
Length = 315
Score = 30.4 bits (67), Expect = 3.9
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 228 RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVEN----PEKTIPLAICISMAIVTIGYVL 283
R +S + P+ F+ G ++ Y + VT + + +KTI A C + ++ I V+
Sbjct: 50 RTNSQLQTPMYFFLGHLSFVDICYSSNVTPNMLHNFLSEQKTISYAGCFTQCLLFIALVI 109
Query: 284 TNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNG 333
T YF A + ++ + +S R+ N + + + +G +NG
Sbjct: 110 TEF-YFLASMALDRYVAICSPLHYSSRMSKN--ICISLVTVPYMYGFLNG 156
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 30.0 bits (66), Expect = 5.1
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 17 QGNVNGRLPSLGNKEPP-GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGS 75
+G NG L + +K G +K +L+R+ L+G+ + G + + P G L T
Sbjct: 37 RGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKD 96
Query: 76 VGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGP 120
+ T++ + V A+ + G I +G Y Y E+F P
Sbjct: 97 DSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 141
>gi|52353949 olfactory receptor, family 4, subfamily C, member 46
[Homo sapiens]
Length = 309
Score = 29.3 bits (64), Expect = 8.7
Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 23/204 (11%)
Query: 260 ENP--EKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSL 317
ENP +K I + + I +GYVL V + + + + ++F + S+
Sbjct: 17 ENPKMQKIIFVVFFVIYIITVVGYVLIVVTITASPSLGSPMYLSLAYLSFIDACYS--SV 74
Query: 318 AVPIFVALSCFGS----MNGGVFAVSRLFYVASREGHLPEILSMIH-VRKHTPLPAVIVL 372
P + S +G NG + V + EG L +++ H V PL + ++
Sbjct: 75 NTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIM 134
Query: 373 HPLTMIMLFS-----GDLDSLLNFLSFARWLFIGLAVAGLIY------LRYKCPDMHRPF 421
+ +L G L + + L + F G V L C D H
Sbjct: 135 NQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHM-- 192
Query: 422 KVPLFIPALFSFTCLFMVALSLYS 445
+ LFI A F CL AL L S
Sbjct: 193 -LELFIAANSGFICLLNFALLLVS 215
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.143 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,543,895
Number of Sequences: 37866
Number of extensions: 740190
Number of successful extensions: 1928
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1882
Number of HSP's gapped (non-prelim): 33
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.