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Search of human proteins with 7657457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657457 prostaglandin-D synthase [Homo sapiens]
(199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657457 prostaglandin-D synthase [Homo sapiens] 417 e-117
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens] 75 3e-14
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens] 74 1e-13
gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens] 73 2e-13
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens] 73 2e-13
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens] 72 4e-13
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 71 7e-13
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens] 70 9e-13
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi... 69 3e-12
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens] 69 3e-12
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens] 68 6e-12
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens] 65 5e-11
gi|4504183 glutathione transferase [Homo sapiens] 62 2e-10
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens] 59 2e-09
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens] 57 1e-08
gi|169169045 PREDICTED: similar to glutathione S-transferase alp... 41 8e-04
gi|113418092 PREDICTED: similar to glutathione S-transferase alp... 39 0.002
gi|113417526 PREDICTED: similar to glutathione S-transferase alp... 39 0.002
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom... 39 0.002
gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens] 37 0.011
gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens] 35 0.042
gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo sapi... 29 2.3
gi|26051235 nucleoporin 133kDa [Homo sapiens] 28 3.9
gi|153792230 hypothetical protein LOC57670 [Homo sapiens] 28 3.9
gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide ... 28 3.9
gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens] 27 8.8
gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens] 27 8.8
gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens] 27 8.8
gi|214010216 SMC6 protein [Homo sapiens] 27 8.8
gi|13375848 SMC6 protein [Homo sapiens] 27 8.8
>gi|7657457 prostaglandin-D synthase [Homo sapiens]
Length = 199
Score = 417 bits (1071), Expect = e-117
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT 60
MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
Sbjct: 1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT 60
Query: 61 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL 120
LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
Sbjct: 61 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL 120
Query: 121 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK 180
TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
Sbjct: 121 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK 180
Query: 181 VQAIPAVANWIKRRPQTKL 199
VQAIPAVANWIKRRPQTKL
Sbjct: 181 VQAIPAVANWIKRRPQTKL 199
>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
Length = 218
Score = 75.5 bits (184), Expect = 3e-14
Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 18/200 (9%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+++RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFP---WAEKKQDVK 112
+ QS AI Y+ + +L G TE E+ VD + + D + ++ + +K
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLK 124
Query: 113 EQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHP 172
+ EL P +MQ +LG R W +G+ +T+ DF +F+P+ LD P
Sbjct: 125 PEYLEEL-----PTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFP 179
Query: 173 RLVTLRKKVQAIPAVANWIK 192
L + + + ++ ++K
Sbjct: 180 NLKDFISRFEGLEKISAYMK 199
>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
Length = 225
Score = 73.6 bits (179), Expect = 1e-13
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 22/202 (10%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRI--------EQADWPEIKSTLP--FGKIPILE 55
L Y+++RG A IR + + D YE+ R +++ W ++K L F +P L
Sbjct: 9 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLL 68
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS-----CFPWAEKKQD 110
+ QS AI RY+ + ++ G TE E+ VD I + + DF + C+ + +
Sbjct: 69 DGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY--SSDHEK 126
Query: 111 VKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN 170
+K Q EL P ++ +LG W G +T+ DF +F P LD
Sbjct: 127 LKPQYLEEL-----PGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDE 181
Query: 171 HPRLVTLRKKVQAIPAVANWIK 192
P L + +A+ +A +++
Sbjct: 182 FPNLKAFMCRFEALEKIAAYLQ 203
>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
Length = 218
Score = 72.8 bits (177), Expect = 2e-13
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 24/203 (11%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+++RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 109
+ QS AI Y+ + +L G TE E+ VD + + T+D+ M C+ P EK
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK-- 122
Query: 110 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 169
+K + EL P ++ +LG R W GN +T+ DF +F+P LD
Sbjct: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176
Query: 170 NHPRLVTLRKKVQAIPAVANWIK 192
P L + + + ++ ++K
Sbjct: 177 AFPNLKDFISRFEGLEKISAYMK 199
>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
Length = 195
Score = 72.8 bits (177), Expect = 2e-13
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 18/182 (9%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+++RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFP---WAEKKQDVK 112
+ QS AI Y+ + +L G TE E+ VD + + D + ++ + +K
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLK 124
Query: 113 EQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHP 172
+ EL P +MQ +LG R W +G+ +T+ DF +F+P+ LD P
Sbjct: 125 PEYLEEL-----PTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFP 179
Query: 173 RL 174
L
Sbjct: 180 NL 181
>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
Length = 218
Score = 71.6 bits (174), Expect = 4e-13
Identities = 53/198 (26%), Positives = 87/198 (43%), Gaps = 14/198 (7%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+N+RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 56 VDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQ 114
+DG + QS AI RY+ + +L G +E EQ D + + D S A+ D +
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD--SRMQLAKLCYDPDFE 121
Query: 115 MFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRL 174
P +++ +LG + W +G+ +T+ DF VF+P LD P L
Sbjct: 122 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 181
Query: 175 VTLRKKVQAIPAVANWIK 192
+ + + ++ ++K
Sbjct: 182 KDFISRFEGLEKISAYMK 199
>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
Length = 222
Score = 70.9 bits (172), Expect = 7e-13
Identities = 52/197 (26%), Positives = 105/197 (53%), Gaps = 12/197 (6%)
Query: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDGLTL 61
KL Y N+RGR E IR++ A +++E+ I+ A D ++++ L F ++P++E+DG+ L
Sbjct: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD---TLDDFMSCFPWAE-KKQDVKEQMFN 117
Q+ AI Y+ +L G E+ +D ++ L + + P+++ ++QD K +
Sbjct: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQ 125
Query: 118 ELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLV 175
E T N P + L ++ G+++L+GN ++ AD + + L+ + P L
Sbjct: 126 E-KTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182
Query: 176 TLRKKVQAIPAVANWIK 192
L+ ++ +P V +++
Sbjct: 183 ALKTRISNLPTVKKFLQ 199
>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
Length = 222
Score = 70.5 bits (171), Expect = 9e-13
Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 10/202 (4%)
Query: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 61
KL Y N RG E IR++ A ++ E+ +E A D ++++ +L F ++P++E+DG+ L
Sbjct: 6 KLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEIDGMKL 65
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVD----AIVDTLDDFMSCFPWAEKKQDVKEQMFN 117
Q+ AI Y+ +L G E+ +D IVD + + +++D K +
Sbjct: 66 VQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAKTALVK 125
Query: 118 ELLTYN-APHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVT 176
E + P + L ++ +++L+GN ++WAD + + L+ + P L
Sbjct: 126 EKIKNRYFPAFEKVLKSH--RQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPLLKA 183
Query: 177 LRKKVQAIPAVANWIKRRPQTK 198
L+ ++ +P V +++ Q K
Sbjct: 184 LKTRISNLPTVKKFLQPGSQRK 205
>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
sapiens]
Length = 191
Score = 68.9 bits (167), Expect = 3e-12
Identities = 52/180 (28%), Positives = 79/180 (43%), Gaps = 14/180 (7%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+N+RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63
Query: 56 VDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQ 114
+DG + QS AI RY+ + +L G +E EQ D + + D S A+ D +
Sbjct: 64 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD--SRMQLAKLCYDPDFE 121
Query: 115 MFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRL 174
P +++ +LG + W +G+ +T+ DF VF+P LD P L
Sbjct: 122 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 181
>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
Length = 222
Score = 68.6 bits (166), Expect = 3e-12
Identities = 51/200 (25%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDGLTL 61
KL YFN RGR E R++ A +++E+ I+ A D ++++ L F ++P++E+DG+ L
Sbjct: 6 KLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDD------FMSCFPWAEKKQD---VK 112
Q+ AI Y+ +L G E+ +D ++ + D + P EK +K
Sbjct: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIK 125
Query: 113 EQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHP 172
E++ N P + L ++ G+++L+GN ++ AD + + L+ + P
Sbjct: 126 EKIKNRYF----PAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179
Query: 173 RLVTLRKKVQAIPAVANWIK 192
L L+ ++ +P V +++
Sbjct: 180 LLKALKTRISNLPTVKKFLQ 199
>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
Length = 222
Score = 67.8 bits (164), Expect = 6e-12
Identities = 55/203 (27%), Positives = 103/203 (50%), Gaps = 24/203 (11%)
Query: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 61
KL YFN RGR E IR++ A +++E+ I A D ++++ +L F ++P++E+DG+ L
Sbjct: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS-------CFPWAEKKQDVKEQ 114
Q+ AI Y+ +L G E+ +D + + D C P +++D K
Sbjct: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP---EEKDAKIA 122
Query: 115 MFNE-LLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPD----LLD 169
+ E + P + L ++ G+++L+GN ++ AD I LL + + L+
Sbjct: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRAD----ISLVELLYYVEELDSSLIS 176
Query: 170 NHPRLVTLRKKVQAIPAVANWIK 192
N P L L+ ++ +P V +++
Sbjct: 177 NFPLLKALKTRISNLPTVKKFLQ 199
>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
Length = 218
Score = 64.7 bits (156), Expect = 5e-11
Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 24/203 (11%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+++RG A IR + Y D Y + + D P+ K L F +P L
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 109
+ QS AI RY+ + +L G TE E+ VD + + +D+ M C+ P EK
Sbjct: 65 DGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEK-- 122
Query: 110 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 169
+K + EL P ++ +LG R W G+ +T+ DF +F+P LD
Sbjct: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLD 176
Query: 170 NHPRLVTLRKKVQAIPAVANWIK 192
L + + + ++ ++K
Sbjct: 177 AFLNLKDFISRFEGLKKISAYMK 199
>gi|4504183 glutathione transferase [Homo sapiens]
Length = 210
Score = 62.4 bits (150), Expect = 2e-10
Identities = 47/193 (24%), Positives = 86/193 (44%), Gaps = 13/193 (6%)
Query: 1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE--IKSTLPFGKIPILEVDG 58
MP Y + YF +RGR +R + A +++ + W E +K++ +G++P +
Sbjct: 1 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGD 60
Query: 59 LTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCF------PWAEKKQDVK 112
LTL+QS I R+L + L G + E VD + D ++D + + K D
Sbjct: 61 LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV 120
Query: 113 EQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHP 172
+ + +L + L GG+ +++G+ +++AD+ V P LD P
Sbjct: 121 KALPGQLKPFETL-----LSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFP 175
Query: 173 RLVTLRKKVQAIP 185
L ++ A P
Sbjct: 176 LLSAYVGRLSARP 188
>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
Length = 222
Score = 59.3 bits (142), Expect = 2e-09
Identities = 51/199 (25%), Positives = 98/199 (49%), Gaps = 16/199 (8%)
Query: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWP---EIKSTLPFGKIPILEVDGLTL 61
KL Y N RGR E +R++ A +++++ +E + + + L F ++P++E+DG+ L
Sbjct: 6 KLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKL 65
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLD--DFMSCFPWAEKKQDVKE--QMF 116
Q+ +I Y+ +L G E+ +D V+ TLD + + P+ + KE M
Sbjct: 66 VQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMA 125
Query: 117 NELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFK---PDLLDNHPR 173
+ + P + L + G+ +L+GN ++ AD I T+L + P++L P
Sbjct: 126 QKAIIRYFPVFEKILRGH--GQSFLVGNQLSLADV---ILLQTILALEEKIPNILSAFPF 180
Query: 174 LVTLRKKVQAIPAVANWIK 192
L K+ IP + +++
Sbjct: 181 LQEYTVKLSNIPTIKRFLE 199
>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
Length = 181
Score = 56.6 bits (135), Expect = 1e-08
Identities = 47/155 (30%), Positives = 70/155 (45%), Gaps = 24/155 (15%)
Query: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55
L Y+++RG A IR + Y D YE+ + D P+ K L F +P L
Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
Query: 56 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 109
+ QS AI Y+ + +L G TE E+ VD + + T+D+ M C+ P EK
Sbjct: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK-- 122
Query: 110 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGN 144
+K + EL P ++ +LG R W GN
Sbjct: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGN 151
>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 227
Score = 40.8 bits (94), Expect = 8e-04
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 29/176 (16%)
Query: 48 FGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQC-------------HVDAIVDT 94
F ++P++E+DG+ L Q+ AI Y+ +L G E+ +++
Sbjct: 41 FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 100
Query: 95 LDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGRE--WLIGNSVTWADFY 152
+ + C +++D K + E T H +T L E +LIGN ++ AD +
Sbjct: 101 SEKLLHCSLHPPEEKDAKLALIKEGTT---SHYFPVFETVLKSHEQDYLIGNKLSQADIH 157
Query: 153 WEICSTTLLVFKPD--LLDNHP-------RLVTLRKKVQAIPAVANWIKRRPQTKL 199
+ V +PD L+ N P L L+ ++ +P V +++ KL
Sbjct: 158 --LVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKL 211
>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 39.3 bits (90), Expect = 0.002
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 29/176 (16%)
Query: 48 FGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQC-------------HVDAIVDT 94
F ++P++E+DG+ L Q+ AI Y+ +L G E+ +++
Sbjct: 30 FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 89
Query: 95 LDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGRE--WLIGNSVTWADFY 152
+ + C +++D K + E T H +T L E + IGN ++ AD +
Sbjct: 90 SEKLLHCSLHPPEEKDAKLALIKEGTT---SHYFPVFETVLKSHEQDYFIGNKLSQADIH 146
Query: 153 WEICSTTLLVFKPD--LLDNHP-------RLVTLRKKVQAIPAVANWIKRRPQTKL 199
+ V +PD L+ N P L L+ ++ +P V +++ KL
Sbjct: 147 --LVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKL 200
>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
3 [Homo sapiens]
Length = 216
Score = 39.3 bits (90), Expect = 0.002
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 29/176 (16%)
Query: 48 FGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQC-------------HVDAIVDT 94
F ++P++E+DG+ L Q+ AI Y+ +L G E+ +++
Sbjct: 30 FQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 89
Query: 95 LDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGRE--WLIGNSVTWADFY 152
+ + C +++D K + E T H +T L E + IGN ++ AD +
Sbjct: 90 SEKLLHCSLHPPEEKDAKLALIKEGTT---SHYFPVFETVLKSHEQDYFIGNKLSQADIH 146
Query: 153 WEICSTTLLVFKPD--LLDNHP-------RLVTLRKKVQAIPAVANWIKRRPQTKL 199
+ V +PD L+ N P L L+ ++ +P V +++ KL
Sbjct: 147 --LVKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKL 200
>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
sapiens]
Length = 437
Score = 39.3 bits (90), Expect = 0.002
Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 12/132 (9%)
Query: 40 PEIKSTLPFGKIPILEVD-GLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF 98
PE P GK+P E D G + +S AIA Y++ N +L G+T V V D
Sbjct: 47 PEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVS-NEELRGSTPEAAAQVVQWVSFADSD 105
Query: 99 M--SCFPWAEKKQDVKEQMFNELLTYNAPH----LMQDLDTYLGGREWLIGNSVTWADFY 152
+ W + N+ T NA ++ LD YL R +L+G VT AD
Sbjct: 106 IVPPASTWVFPTLGIMHH--NKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADI- 162
Query: 153 WEICSTTLLVFK 164
+ T L ++K
Sbjct: 163 -TVVCTLLWLYK 173
>gi|22202624 glutathione transferase zeta 1 isoform 1 [Homo sapiens]
Length = 216
Score = 37.0 bits (84), Expect = 0.011
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 10/147 (6%)
Query: 47 PFGKIPILEVDGLTLHQSLAIARYLTK---NTDLAGNTEMEQCHVDAIVDTLDDFMSCFP 103
P ++P L++DG+T+HQSLAI YL + L ++ V I D + +
Sbjct: 55 PMKQVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQ 114
Query: 104 WAEKKQDVKEQM----FNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTT 159
+ V E+M +T L Q L + G + +G+ VT AD
Sbjct: 115 NLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAG--IYCVGDEVTMADLCLVPQVAN 172
Query: 160 LLVFKPDLLDNHPRLVTLRKKVQAIPA 186
FK DL +P + ++ K++ + A
Sbjct: 173 AERFKVDLTP-YPTISSINKRLLVLEA 198
>gi|22202622 glutathione transferase zeta 1 isoform 3 [Homo sapiens]
Length = 161
Score = 35.0 bits (79), Expect = 0.042
Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 10/144 (6%)
Query: 50 KIPILEVDGLTLHQSLAIARYLTK---NTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAE 106
++P L++DG+T+HQSLAI YL + L ++ V I D + +
Sbjct: 3 QVPTLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLS 62
Query: 107 KKQDVKEQM----FNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLV 162
+ V E+M +T L Q L + G + +G+ VT AD
Sbjct: 63 VLKQVGEEMQLTWAQNAITCGFNALEQILQSTAG--IYCVGDEVTMADLCLVPQVANAER 120
Query: 163 FKPDLLDNHPRLVTLRKKVQAIPA 186
FK DL +P + ++ K++ + A
Sbjct: 121 FKVDLTP-YPTISSINKRLLVLEA 143
>gi|194440732 glutathione transferase zeta 1 isoform 2 [Homo
sapiens]
Length = 174
Score = 29.3 bits (64), Expect = 2.3
Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 47 PFGKIPILEVDGLTLHQS-LAIARYLTKNTDLAGNTEMEQCHVDAIVDTL 95
P ++P L++DG+T+HQS L++ + + + L C +A+ L
Sbjct: 55 PMKQVPTLKIDGITIHQSNLSVLKQVGEEMQLTWAQNAITCGFNALEQIL 104
>gi|26051235 nucleoporin 133kDa [Homo sapiens]
Length = 1156
Score = 28.5 bits (62), Expect = 3.9
Identities = 12/46 (26%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 62 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFP-WAE 106
H + + + ++DL ++E+++ VD +DD+ + P WAE
Sbjct: 536 HAQMVVDELFSSHSDLDSDSELDRAVTQISVDLMDDYPASDPRWAE 581
>gi|153792230 hypothetical protein LOC57670 [Homo sapiens]
Length = 1884
Score = 28.5 bits (62), Expect = 3.9
Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 5/36 (13%)
Query: 152 YWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAV 187
YW++C T L F+PD + N + R+K+Q IP+V
Sbjct: 1270 YWKLCRTDKLDFQPDTVAN----IQQRQKLQ-IPSV 1300
>gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide 1
[Homo sapiens]
Length = 544
Score = 28.5 bits (62), Expect = 3.9
Identities = 15/39 (38%), Positives = 23/39 (58%)
Query: 43 KSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNT 81
K+ +P+ + I+EV LT+ LAI ++NT L G T
Sbjct: 397 KAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYT 435
>gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 27.3 bits (59), Expect = 8.8
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 82 EMEQCHVDAIVDTLDDFMSCFPWAEKKQ--DVKEQM 115
E E VD +VD DF F W +K Q D +EQ+
Sbjct: 59 EQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQL 94
>gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 27.3 bits (59), Expect = 8.8
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 82 EMEQCHVDAIVDTLDDFMSCFPWAEKKQ--DVKEQM 115
E E VD +VD DF F W +K Q D +EQ+
Sbjct: 59 EQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQL 94
>gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 27.3 bits (59), Expect = 8.8
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 82 EMEQCHVDAIVDTLDDFMSCFPWAEKKQ--DVKEQM 115
E E VD +VD DF F W +K Q D +EQ+
Sbjct: 59 EQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQL 94
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 27.3 bits (59), Expect = 8.8
Identities = 21/96 (21%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 26 DIQYEDHRIE--QADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEM 83
DI++ + ++ Q + E+K + I E++ + HQS+ IA + + +M
Sbjct: 695 DIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKM 754
Query: 84 EQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNEL 119
+ H++ + ++ S AE K D + N+L
Sbjct: 755 VEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQL 790
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 27.3 bits (59), Expect = 8.8
Identities = 21/96 (21%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 26 DIQYEDHRIE--QADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEM 83
DI++ + ++ Q + E+K + I E++ + HQS+ IA + + +M
Sbjct: 695 DIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKM 754
Query: 84 EQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNEL 119
+ H++ + ++ S AE K D + N+L
Sbjct: 755 VEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQL 790
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,469,029
Number of Sequences: 37866
Number of extensions: 305817
Number of successful extensions: 584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 541
Number of HSP's gapped (non-prelim): 30
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.