Search of human proteins with 71274132

Search of human proteins with 71274132

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]               525   e-149
gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]                498   e-141
gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]               414   e-116
gi|4502445 bisphosphoglycerate mutase [Homo sapiens]                  292   2e-79
gi|40353764 bisphosphoglycerate mutase [Homo sapiens]                 292   2e-79
gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4...    39   0.004
gi|9966849 TP53-induced glycolysis and apoptosis regulator [Homo...    33   0.31 
gi|24497612 ubiquitin associated and SH3 domain containing, B [H...    32   0.41 
gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 ...    29   4.5  
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]     28   7.7  
gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase...    28   7.7  
gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]            28   7.7  
gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]            28   7.7  
gi|20070384 phosphoglycerate mutase family member 5 [Homo sapiens]     28   7.7  

>gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]
          Length = 254

 Score =  525 bits (1351), Expect = e-149
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60
           MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
Sbjct: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60

Query: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
           KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
Sbjct: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120

Query: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR 180
           VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR
Sbjct: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR 180

Query: 181 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC 240
           VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC
Sbjct: 181 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC 240

Query: 241 KAIEAVAAQGKAKK 254
           KAIEAVAAQGKAKK
Sbjct: 241 KAIEAVAAQGKAKK 254


>gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]
          Length = 254

 Score =  498 bits (1281), Expect = e-141
 Identities = 243/254 (95%), Positives = 246/254 (96%)

Query: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60
           MAAYKLVLIRHGES WNLENRFS WYDADLSPAGHEEAKRGGQALRDAGYEFDIC TSVQ
Sbjct: 1   MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ 60

Query: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
           KR IRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
Sbjct: 61  KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120

Query: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR 180
           VPPPPMEPDHPFYSNISKDRRYADLTEDQLPS ES KDTIARALPFWNEEIVPQIKEGKR
Sbjct: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR 180

Query: 181 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC 240
           VLIAAHGNSL+GI KH+EGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETV 
Sbjct: 181 VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR 240

Query: 241 KAIEAVAAQGKAKK 254
           KA+EAVAAQGKAKK
Sbjct: 241 KAMEAVAAQGKAKK 254


>gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]
          Length = 253

 Score =  414 bits (1065), Expect = e-116
 Identities = 197/253 (77%), Positives = 223/253 (88%)

Query: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60
           MA ++LV++RHGESTWN ENRF  W+DA+LS  G EEAKRG +A++DA  EFDIC TSV 
Sbjct: 1   MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVL 60

Query: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
           KR IRTLW +LD  DQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGE QVKIWRRS+D
Sbjct: 61  KRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFD 120

Query: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR 180
           +PPPPM+  HP+Y++ISK+RRYA L   +LP+ ES KDTIARALPFWNEEIVPQIK GKR
Sbjct: 121 IPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKR 180

Query: 181 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC 240
           VLIAAHGNSL+GI KH+EG+S++AIMELNLPTGIPIVYEL+K LKP KPMQFLGDEETV 
Sbjct: 181 VLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVR 240

Query: 241 KAIEAVAAQGKAK 253
           KA+EAVAAQGKAK
Sbjct: 241 KAMEAVAAQGKAK 253


>gi|4502445 bisphosphoglycerate mutase [Homo sapiens]
          Length = 259

 Score =  292 bits (747), Expect = 2e-79
 Identities = 133/256 (51%), Positives = 178/256 (69%), Gaps = 2/256 (0%)

Query: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60
           M+ YKL+++RHGE  WN ENRF  W D  L+  G EEA+  G+ L+   +EFD+  TSV 
Sbjct: 1   MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL 60

Query: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
            R I T W +L+ + Q W+PV  +WRLNERHYG L GLN+ + A  HGE QV++WRRSY+
Sbjct: 61  NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN 120

Query: 121 VPPPPMEPDHPFYSNISKDRRY--ADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG 178
           V PPP+E  HP+Y  I  DRRY   D+  DQLP  ES KD + R LP+WNE I P++  G
Sbjct: 121 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG 180

Query: 179 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET 238
           K +LI+AHGNS + + KH+EG+S+E I+ + LPTG+PI+ ELD+NL+ + P QFLGD+E 
Sbjct: 181 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA 240

Query: 239 VCKAIEAVAAQGKAKK 254
           +  AI+ V  QGK K+
Sbjct: 241 IQAAIKKVEDQGKVKQ 256


>gi|40353764 bisphosphoglycerate mutase [Homo sapiens]
          Length = 259

 Score =  292 bits (747), Expect = 2e-79
 Identities = 133/256 (51%), Positives = 178/256 (69%), Gaps = 2/256 (0%)

Query: 1   MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ 60
           M+ YKL+++RHGE  WN ENRF  W D  L+  G EEA+  G+ L+   +EFD+  TSV 
Sbjct: 1   MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL 60

Query: 61  KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
            R I T W +L+ + Q W+PV  +WRLNERHYG L GLN+ + A  HGE QV++WRRSY+
Sbjct: 61  NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN 120

Query: 121 VPPPPMEPDHPFYSNISKDRRY--ADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG 178
           V PPP+E  HP+Y  I  DRRY   D+  DQLP  ES KD + R LP+WNE I P++  G
Sbjct: 121 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG 180

Query: 179 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET 238
           K +LI+AHGNS + + KH+EG+S+E I+ + LPTG+PI+ ELD+NL+ + P QFLGD+E 
Sbjct: 181 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA 240

Query: 239 VCKAIEAVAAQGKAKK 254
           +  AI+ V  QGK K+
Sbjct: 241 IQAAIKKVEDQGKVKQ 256


>gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           [Homo sapiens]
          Length = 469

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 11/79 (13%)

Query: 6   LVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIR 65
           + L RHGES  NL+ R     D  LSP G E AK   Q + D   +     TS  KR I+
Sbjct: 252 IYLCRHGESELNLKGRIGG--DPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQ 309

Query: 66  TL---------WTVLDAID 75
           T          W VL+ ID
Sbjct: 310 TAEALGVPYEQWKVLNEID 328


>gi|9966849 TP53-induced glycolysis and apoptosis regulator [Homo
           sapiens]
          Length = 270

 Score = 32.7 bits (73), Expect = 0.31
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 9/127 (7%)

Query: 1   MAAYKLVLIRHGESTWNLENRF-SCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSV 59
           MA + L ++RHGE+ +N E        D  LS  G ++A   G  L +   +F    +S 
Sbjct: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNV--KFTHAFSSD 58

Query: 60  QKRVIRTLWTVLDAIDQMW-LPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRS 118
             R  +T+  +L+       + V    RL ER YG + G   +E       A  K  R  
Sbjct: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSEL-----RAMAKAAREE 113

Query: 119 YDVPPPP 125
             V  PP
Sbjct: 114 CPVFTPP 120


>gi|24497612 ubiquitin associated and SH3 domain containing, B [Homo
           sapiens]
          Length = 649

 Score = 32.3 bits (72), Expect = 0.41
 Identities = 39/178 (21%), Positives = 68/178 (38%), Gaps = 23/178 (12%)

Query: 27  DADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIRTLWTVLDAIDQMWLPVVRTWR 86
           DA ++  G  +A+  G+AL ++    D    S   R ++T   +L  + Q          
Sbjct: 438 DAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQE--------- 488

Query: 87  LNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD-L 145
                       N  +   + G  +   W     +P   + P     +N+S D  Y   +
Sbjct: 489 ------------NHLKIRVEPGLFEWTKWVAGSTLPAW-IPPSELAAANLSVDTTYRPHI 535

Query: 146 TEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLQGIAKHVEGLSEE 203
              +L   ES    I+R+     E I     +G  +LI AH +SL+     ++GLS +
Sbjct: 536 PISKLVVSESYDTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQ 593


>gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1
           [Homo sapiens]
          Length = 740

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 16/41 (39%), Positives = 20/41 (48%)

Query: 92  YGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPF 132
           YGG+    KA  AAKHG A V ++    D+      PD  F
Sbjct: 193 YGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETF 233


>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
          Length = 1280

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 4/52 (7%)

Query: 111 QVKIWRRSYDVPPPPME----PDHPFYSNISKDRRYADLTEDQLPSYESPKD 158
           Q + W R YDV  PP         P+    + +R+Y  LT+ QL      K+
Sbjct: 59  QQQSWVRVYDVKGPPTHRLSCGQSPYTETTTWERKYCILTDSQLVLLNKEKE 110


>gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
           [Homo sapiens]
          Length = 471

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 11/79 (13%)

Query: 6   LVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIR 65
           + L RHGES  N+  R     D+ LS  G + A      ++  G       TS  KR I+
Sbjct: 254 IYLCRHGESELNIRGRIG--GDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311

Query: 66  TL---------WTVLDAID 75
           T          W  L+ ID
Sbjct: 312 TAEALGVPYEQWKALNEID 330


>gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]
          Length = 796

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 17/92 (18%)

Query: 147 EDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLI-----------AAHGNSLQGIAK 195
           E Q   ++ P +     LPFW +  +P I+E  R +                NS QG+ K
Sbjct: 356 EIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDQGLEK 415

Query: 196 HVEGLSEEAIMELNLPTGIPIVYELDKNLKPI 227
               L  E    L LP G+ +       LKP+
Sbjct: 416 DNSELGSETRYPLLLPKGVVL------KLKPV 441


>gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]
          Length = 750

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 17/92 (18%)

Query: 147 EDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLI-----------AAHGNSLQGIAK 195
           E Q   ++ P +     LPFW +  +P I+E  R +                NS QG+ K
Sbjct: 310 EIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDQGLEK 369

Query: 196 HVEGLSEEAIMELNLPTGIPIVYELDKNLKPI 227
               L  E    L LP G+ +       LKP+
Sbjct: 370 DNSELGSETRYPLLLPKGVVL------KLKPV 395


>gi|20070384 phosphoglycerate mutase family member 5 [Homo sapiens]
          Length = 255

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 2   AAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQK 61
           A   + LIRH  S ++++   S   D  L+P G E+A+  G  L   G +F+  + S   
Sbjct: 96  ATRHIFLIRH--SQYHVDG--SLEKDRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMT 151

Query: 62  RVIRT 66
           R I T
Sbjct: 152 RAIET 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,491,912
Number of Sequences: 37866
Number of extensions: 470046
Number of successful extensions: 1355
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1343
Number of HSP's gapped (non-prelim): 14
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.